| 1 |
NDUFB7 | parental protein | 33 | 0.239 | 862.703 | DUF106 (PF01956, IPR002809): Integral membrane protein DUF106
NDUF_B7 (PF05676, IPR008698): NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7)
OrfB_IS605 (PF01385, IPR001959): Probable transposase |
| 2 |
DRG1 | parental protein | 43 | 0.099 | 2126.030 | MMR_HSR1 (PF01926, IPR006073): 50S ribosome-binding GTPase
TGS (PF02824, IPR004095): TGS domain
MMR_HSR1_Xtn (PF16897, IPR031662): C-terminal region of MMR_HSR1 domain |
| 3 |
ABL1 | oncoprotein | 9 | 0.393 | 29.945 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
F_actin_bind (PF08919, IPR015015, SM00808): F-actin binding
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
FRG2 (PF15315, IPR026245): Facioscapulohumeral muscular dystrophy candidate 2 |
| 4 |
ATP1B3 | interactor | 14 | 0.341 | 196.197 | Na_K-ATPase (PF00287, IPR000402): Sodium / potassium ATPase beta chain |
| 5 |
ATP5F1 | interactor | 12 | 0.424 | 53.088 | Mt_ATP-synt_B (PF05405, IPR008688): Mitochondrial ATP synthase B chain precursor (ATP-synt_B)
DUF2105 (PF09878, IPR019212): Predicted membrane protein (DUF2105) |
| 6 |
ATP6V0D1 | interactor | 9 | 0.417 | 19.873 | vATP-synt_AC39 (PF01992, IPR002843): ATP synthase (C/AC39) subunit |
| 7 |
BARD1 | suppressor | 6 | 0.400 | 25.726 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
zf-RING_6 (PF14835): zf-RING of BARD1-type protein
BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain |
| 8 |
BRCA1 | suppressor | 8 | 0.238 | 72.194 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT |
| 9 |
CAND1 | interactor | 11 | 0.444 | 31.163 | Adaptin_N (PF01602, IPR002553): Adaptin N terminal region
DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981)
HEAT (PF02985, IPR000357): HEAT repeat
TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20)
RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1
DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385)
MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II |
| 10 |
CAND2 | interactor | 2 | 1.000 | 0 | Adaptin_N (PF01602, IPR002553): Adaptin N terminal region
RIX1 (PF08167, IPR012583): rRNA processing/ribosome biogenesis
TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20)
HEAT_PBS (PF03130, IPR004155, SM00567): PBS lyase HEAT-like repeat
CAF1A (PF12253, IPR022043): Chromatin assembly factor 1 subunit A
MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal
TFCD_C (PF12612, IPR022577): Tubulin folding cofactor D C terminal
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats |
| 11 |
CAPN1 | interactor | 6 | 0.333 | 37.085 | Calpain_III (PF01067, IPR022682, SM00720): Calpain large subunit, domain III
Peptidase_C2 (PF00648, IPR001300, SM00230): Calpain family cysteine protease
EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_8 (PF13833, IPR002048): EF-hand domain pair |
| 12 |
CAPNS1 | interactor | 5 | 0.800 | 8.042 | EF-hand_1 (PF00036, IPR002048, SM00054): EF hand
EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_8 (PF13833, IPR002048): EF-hand domain pair |
| 13 |
CCDC8 | interactor | 10 | 0.361 | 92.852 | Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
PNMA (PF14893, IPR026523): PNMA |
| 14 |
CD55 | oncoprotein | 4 | 0.667 | 1.000 | Sushi (PF00084, IPR000436, SM00032): Sushi repeat (SCR repeat)
MAGE_N (PF12440, IPR021072): Melanoma associated antigen family N terminal
HYLS1_C (PF15311, IPR027918): Hydrolethalus syndrome protein 1 C-terminus |
| 15 |
CDC5L | interactor | 12 | 0.436 | 65.114 | OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat
Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component
Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain |
| 16 |
CKAP4 | protein found in more fusions | 12 | 0.255 | 170.336 | DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180)
FPP (PF05911, IPR008587): Filament-like plant protein, long coiled-coil
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200) |
| 17 |
CLDN1 | suppressor | 1 | 0 | 0 | PMP22_Claudin (PF00822, IPR004031): PMP-22/EMP/MP20/Claudin family
DUF4131 (PF13567, IPR025405): Domain of unknown function (DUF4131) |
| 18 |
COIL | interactor | 4 | 0.667 | 1.000 | CDC45 (PF02724, IPR003874): CDC45-like protein
Macoilin (PF09726, IPR019130): Transmembrane protein
Coilin_N (PF15862, IPR031722): Coilin N-terminus |
| 19 |
COX4I1 | interactor | 9 | 0.583 | 7.195 | COX4 (PF02936, IPR004203): Cytochrome c oxidase subunit IV |
| 20 |
CUL7 | protein found in more fusions | 12 | 0.309 | 136.008 | ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10)
Cullin (PF00888, IPR001373, SM00182): Cullin family
DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918)
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7 |
| 21 |
FEN1 | oncoprotein | 6 | 0.600 | 4.598 | 5_3_exonuc (PF01367, IPR020045, SM00475): 5'-3' exonuclease, C-terminal SAM fold
XPG_I (PF00867, IPR006086, SM00484): XPG I-region
XPG_N (PF00752, IPR006085, SM00485): XPG N-terminal domain |
| 22 |
FN1 | oncoprotein | 16 | 0.225 | 269.440 | fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain
fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) |
| 23 |
GOLT1B | interactor | 16 | 0.458 | 42.353 | Got1 (PF04178, IPR007305): Got1/Sft2-like family |
| 24 |
GRB2 | oncoprotein | 9 | 0.321 | 53.174 | SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
DUF5093 (PF17011, IPR031533): Domain of unknown function (DUF5093) |
| 25 |
HAO1 | interactor | 1 | 0 | 0 | FMN_dh (PF01070, IPR000262): FMN-dependent dehydrogenase |
| 26 |
HDGF | interactor | 6 | 0.667 | 11.849 | PWWP (PF00855, IPR000313, SM00293): PWWP domain |
| 27 |
HECW2 | interactor | 4 | 0.667 | 2.000 | C2 (PF00168, IPR000008, SM00239): C2 domain
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
Cep57_CLD (PF14073, IPR025913): Centrosome localisation domain of Cep57
RFXA_RFXANK_bdg (PF15289, IPR029316): Regulatory factor X-associated C-terminal binding domain
HECW_N (PF16562, IPR032348): N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 |
| 28 |
HSPA1L | interactor | 7 | 0.238 | 143.778 | HSP70 (PF00012, IPR013126): Hsp70 protein |
| 29 |
IFRD2 | oncoprotein | 1 | 0 | 0 | IFRD (PF05004, IPR007701): Interferon-related developmental regulator (IFRD)
IFRD_C (PF04836, IPR006921): Interferon-related protein conserved region |
| 30 |
ITGA4 | interactor | 14 | 0.385 | 139.152 | FG-GAP (PF01839, IPR013517): FG-GAP repeat
Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region
Integrin_alpha2 (PF08441, IPR013649): Integrin alpha |
| 31 |
KIF23 | interactor | 2 | 1.000 | 0 | DUF730 (PF05325, IPR007989): Protein of unknown function (DUF730)
Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
MKLP1_Arf_bdg (PF16540, IPR032384): Arf6-interacting domain of mitotic kinesin-like protein 1 |
| 32 |
LAMTOR3 | interactor | 7 | 0.429 | 8.465 | MAPKK1_Int (PF08923, IPR015019): Mitogen-activated protein kinase kinase 1 interacting |
| 33 |
LRRC41 | interactor | 3 | 0.667 | 1.788 | LRR_6 (PF13516, IPR001611): Leucine Rich repeat |
| 34 |
MAK | interactor | 2 | 0 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain
DUF4106 (PF13388, IPR025179): Protein of unknown function (DUF4106) |
| 35 |
MAST3 | interactor | 2 | 0 | 8.650 | DUF1908 (PF08926, IPR015022): Domain of unknown function (DUF1908)
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
Pkinase (PF00069, IPR000719): Protein kinase domain
ACTL7A_N (PF16840, IPR031769): Actin-like protein 7A N-terminus |
| 36 |
MLKL | interactor | 2 | 0 | 30.310 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Kinase-like (PF14531, IPR027916): Kinase-like |
| 37 |
MMGT1 | interactor | 8 | 0.607 | 15.548 | MMgT (PF10270, IPR018937): Membrane magnesium transporter |
| 38 |
MPV17 | interactor | 8 | 0.500 | 13.453 | Mpv17_PMP22 (PF04117, IPR007248): Mpv17 / PMP22 family |
| 39 |
MRPL58 | interactor | 9 | 0.639 | 5.571 | RF-1 (PF00472, IPR000352): RF-1 domain |
| 40 |
NAA15 | interactor | 6 | 0.467 | 25.320 | NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
TPR_7 (PF13176, IPR019734): Tetratricopeptide repeat
TPR_8 (PF13181, IPR019734): Tetratricopeptide repeat
TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat |
| 41 |
NDUFA10 | interactor | 10 | 0.556 | 74.840 | dNK (PF01712, IPR002624): Deoxynucleoside kinase |
| 42 |
NDUFA12 | interactor | 15 | 0.600 | 29.001 | NDUFA12 (PF05071, IPR007763): NADH ubiquinone oxidoreductase subunit NDUFA12 |
| 43 |
NDUFA2 | interactor | 20 | 0.368 | 234.505 | L51_S25_CI-B8 (PF05047, IPR007741, SM00916): Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain |
| 44 |
NDUFA4 | interactor | 16 | 0.524 | 97.318 | B12D (PF06522, IPR010530): NADH-ubiquinone reductase complex 1 MLRQ subunit |
| 45 |
NDUFA8 | interactor | 10 | 0.711 | 9.187 | CHCH (PF06747, IPR010625): CHCH domain
Pet191_N (PF10203, IPR018793): Cytochrome c oxidase assembly protein PET191
Cdd1 (PF11731, IPR021725): Pathogenicity locus |
| 46 |
NDUFA9 | interactor | 18 | 0.490 | 127.467 | Epimerase (PF01370, IPR001509): NAD dependent epimerase/dehydratase family |
| 47 |
NDUFB10 | interactor | 7 | 1.000 | 0 | NDUFB10 (PF10249, IPR019377): NADH-ubiquinone oxidoreductase subunit 10 |
| 48 |
NDUFB9 | interactor | 13 | 0.564 | 37.049 | Complex1_LYR (PF05347, IPR008011): Complex 1 protein (LYR family) |
| 49 |
NDUFS3 | protein found in more fusions | 22 | 0.386 | 269.352 | Complex1_30kDa (PF00329, IPR001268): Respiratory-chain NADH dehydrogenase, 30 Kd subunit |
| 50 |
NDUFS5 | interactor | 11 | 0.709 | 11.360 | Ndufs5 (PF10200, IPR019342): NADH:ubiquinone oxidoreductase, NDUFS5-15kDa |
| 51 |
NTMT1 | interactor | 1 | 0 | 0 | Methyltransf_PK (PF05891, IPR008576): AdoMet dependent proline di-methyltransferase |
| 52 |
NTRK1 | oncoprotein | 26 | 0.167 | 775.427 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain |
| 53 |
PAXIP1 | interactor | 7 | 0.381 | 42.755 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
IPT (PF01745, IPR002648, SM00429): Isopentenyl transferase
SURF6 (PF04935, IPR007019): Surfeit locus protein 6
DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052)
CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance
PTCB-BRCT (PF12738, IPR001357): twin BRCT domain
BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain
LIG3_BRCT (PF16759, IPR031916): DNA ligase 3 BRCT domain
RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain |
| 54 |
PHB2 | interactor | 16 | 0.275 | 221.312 | DUF2605 (PF10792, IPR019728): Protein of unknown function (DUF2605)
Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family |
| 55 |
PHC2 | interactor | 5 | 0.500 | 3.327 | SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
zf-CGNR (PF11706, IPR021005): CGNR zinc finger
DUF4692 (PF15763, IPR031517): Domain of unknown function (DUF4692)
PHC2_SAM_assoc (PF16616): Unstructured region on Polyhomeotic-like protein 1 and 2 |
| 56 |
PHKG2 | interactor | 3 | 0.333 | 64.974 | APH (PF01636, IPR002575): Phosphotransferase enzyme family
Pkinase (PF00069, IPR000719): Protein kinase domain |
| 57 |
RAB5C | oncoprotein | 17 | 0.265 | 249.796 | Ras (PF00071, IPR001806, SM00173): Ras family |
| 58 |
RAB7A | suppressor | 9 | 0.361 | 35.507 | Ras (PF00071, IPR001806, SM00173): Ras family |
| 59 |
RPL10 | suppressor | 11 | 0.345 | 48.734 | Ribosomal_L16 (PF00252, IPR016180): Ribosomal protein L16p/L10e |
| 60 |
RWDD1 | interactor | 2 | 1.000 | 0 | RWD (PF05773, IPR006575, SM00591): RWD domain
Folliculin (PF11704, IPR021713): Vesicle coat protein involved in Golgi to plasma membrane transport
DFRP_C (PF16543, IPR032378): DRG Family Regulatory Proteins, Tma46 |
| 61 |
SFN | suppressor | 6 | 0.600 | 15.099 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |
| 62 |
SKIL | suppressor | 5 | 0.500 | 6.708 | c-SKI_SMAD_bind (PF08782, IPR014890, SM01046): c-SKI Smad4 binding domain
DUF489 (PF04356, IPR007451): Protein of unknown function (DUF489)
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
Ski_Sno (PF02437, IPR003380): SKI/SNO/DAC family
DUF2115 (PF09888, IPR019215): Uncharacterized protein conserved in archaea (DUF2115) |
| 63 |
SNW1 | protein found in more fusions | 10 | 0.361 | 119.128 | SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
SIR4_SID (PF16991, IPR031556): Sir4 SID domain |
| 64 |
SRPK2 | oncoprotein | 6 | 0.600 | 4.589 | DUF1387 (PF07139, IPR009816): Protein of unknown function (DUF1387)
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
Pkinase (PF00069, IPR000719): Protein kinase domain
S-antigen (PF05756, IPR008825): S-antigen protein
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) |
| 65 |
SSX2IP | protein found in more fusions | 5 | 0.500 | 3.666 | ZapB (PF06005, IPR009252): Cell division protein ZapB
ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
Surfac_D-trimer (PF09006, IPR015097): Lung surfactant protein D coiled-coil trimerisation
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
YqzH (PF14164, IPR025546): YqzH-like protein |
| 66 |
STAU1 | protein found in more fusions | 16 | 0.362 | 143.420 | dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
Staufen_C (PF16482, IPR032478): Staufen C-terminal domain |
| 67 |
STK16 | interactor | 3 | 1.000 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain |
| 68 |
TAL1 | oncoprotein | 2 | 0 | 0 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
SelK_SelG (PF10961, IPR024491): Selenoprotein SelK_SelG |
| 69 |
TOMM7 | interactor | 1 | 0 | 0 | Tom7 (PF08038, IPR012621): TOM7 family |
| 70 |
UBE2I | interactor | 6 | 0.300 | 67.511 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
| 71 |
UQCRC2 | oncoprotein | 12 | 0.455 | 72.805 | Peptidase_M16 (PF00675, IPR011765): Insulinase (Peptidase family M16)
Peptidase_M16_C (PF05193, IPR007863): Peptidase M16 inactive domain |
| 72 |
UQCRQ | interactor | 10 | 0.511 | 11.925 | UcrQ (PF02939, IPR004205): UcrQ family |
| 73 |
VCAM1 | interactor | 11 | 0.309 | 92.728 | C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain |
| 74 |
VDAC3 | interactor | 10 | 0.444 | 47.217 | Porin_3 (PF01459, IPR027246): Eukaryotic porin |
| 75 |
WWOX | suppressor | 3 | 0.667 | 1.000 | adh_short (PF00106, IPR002198): short chain dehydrogenase
WW (PF00397, IPR001202, SM00456): WW domain |
| 76 |
XPO1 | interactor | 15 | 0.210 | 173.218 | CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region |
| 77 |
ZC3H15 | interactor | 5 | 0.700 | 5.695 | zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
Torus (PF16131, IPR032297): Torus domain
DFRP_C (PF16543, IPR032378): DRG Family Regulatory Proteins, Tma46 |
| 78 |
ZMPSTE24 | interactor | 3 | 0.667 | 6.379 | Peptidase_M48 (PF01435, IPR001915): Peptidase family M48
Peptidase_M48_N (PF16491, IPR032456): CAAX prenyl protease N-terminal, five membrane helices |