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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins IPPK, MUC2 (from a repository: Fri Dec 7 04:06:29 2018)

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)5
The number (and %) of the onco-proteins1 (20.00 %)
The number (and %) of the tumor suppressors1 (20.00 %)
Total number of binary PPIs (saturation %)3 (30.00 %)
The number (and %) of affected PPIs3 (100.00 %)
The number of possible different fusions1
PPI diameter2
PPI radiusinf
The average degree of PPI1.200
Assortativity coefficient0
The network average Clustering coefficient0.000
The number (and %) of a zero Clustering coefficients5 (100.00 %)
The number (and %) of a zero Betweenness Centrality4 (80.00 %)


List of the fusions

PPI for parental proteins: IPPK,MUC2 All fusions
Proteins found in more fusions

List of active interactors

# Name Type Number of PPI (degree) Clustering
Domains (Pfam, InterPro, SMART): description
1 IPPKparental protein100Ins_P5_2-kin (PF06090, IPR009286): Inositol-pentakisphosphate 2-kinase
2 MUC2parental protein202.000C8 (PF08742, IPR014853, SM00832): C8 domain
MGC-24 (PF05283, IPR007947): Multi-glycosylated core protein 24 (MGC-24), sialomucin
Mucin (PF01456, IPR000458): Mucin-like glycoprotein
TIL (PF01826, IPR002919): Trypsin Inhibitor like cysteine rich domain
VWC (PF00093, IPR001007, SM00214): von Willebrand factor type C domain
VWD (PF00094, IPR001846, SM00216): von Willebrand factor type D domain
TILa (PF12714, IPR025615): TILa domain
Mucin2_WxxW (PF13330, IPR025155): Mucin-2 protein WxxW repeating region
3 CDK12oncoprotein100Lamp (PF01299, IPR002000): Lysosome-associated membrane glycoprotein (Lamp)
Mem_trans (PF03547, IPR004776): Membrane transport protein
Pkinase (PF00069, IPR000719): Protein kinase domain
SOBP (PF15279, IPR026092): Sine oculis-binding protein
CCDC106 (PF15794, IPR031591): Coiled-coil domain-containing protein 106
4 GALNT14interactor100Glyco_transf_7C (PF02709, IPR027791): N-terminal domain of galactosyltransferase
Glycos_transf_2 (PF00535, IPR001173): Glycosyl transferase family 2
Ricin_B_lectin (PF00652, IPR000772, SM00458): Ricin-type beta-trefoil lectin domain
DUF4519 (PF15012, IPR027960): Domain of unknown function (DUF4519)
5 MLH1suppressor100DNA_mis_repair (PF01119, IPR013507): DNA mismatch repair protein, C-terminal domain
HATPase_c_3 (PF13589): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
Mlh1_C (PF16413, IPR032189): DNA mismatch repair protein Mlh1 C-terminus

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