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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins ND2, MT-ND4L (from a repository: Sun Apr 16 17:32:02 2017)

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)9
The number (and %) of the onco-proteins1 (11.11 %)
The number (and %) of the tumor suppressors2 (22.22 %)
Total number of binary PPIs (saturation %)12 (33.33 %)
The number (and %) of affected PPIs7 (58.33 %)
The number of possible different fusions2
PPI diameter4
PPI radius2
The average degree of PPI2.222
Assortativity coefficient-0.1458
The network average Clustering coefficient0.311
The number (and %) of a zero Clustering coefficients5 (55.56 %)
The number (and %) of a zero Betweenness Centrality5 (55.56 %)


List of the fusions

PPI for parental proteins: MT-ND4L,MT-ND2 All fusions
Proteins found in more fusions STAT1 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Domains (Pfam, InterPro, SMART): description
1 MT-ND4Lparental protein100Oxidored_q2 (PF00420, IPR001133): NADH-ubiquinone/plastoquinone oxidoreductase chain 4L
2 ND2parental protein60.13345.000NA
3 GRIN1interactor100ANF_receptor (PF01094, IPR001828): Receptor family ligand binding region
Lig_chan (PF00060, IPR001320): Ligand-gated ion channel
CaM_bdg_C0 (PF10562, IPR018882): Calmodulin-binding domain C0 of NMDA receptor NR1 subunit
Lig_chan-Glu_bd (PF10613, IPR019594, SM00918): Ligated ion channel L-glutamate- and glycine-binding site
4 NDUFA11interactor21.00007kD_coat (PF02495, IPR003411): 7kD viral coat protein
Tim17 (PF02466, IPR003397): Tim17/Tim22/Tim23/Pmp24 family
5 SRConcoprotein3024.000Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
6 STAT1suppressor3014.000SH2 (PF00017, IPR000980, SM00252): SH2 domain
STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain
STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain
STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain
STAT1_TAZ2bind (PF12162, IPR022752): STAT1 TAZ2 binding domain
7 STK11suppressor100Pkinase (PF00069, IPR000719): Protein kinase domain
8 TIMMDC1interactor21.0000Tim17 (PF02466, IPR003397): Tim17/Tim22/Tim23/Pmp24 family
9 YME1L1interactor30.6671.000AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
Peptidase_M41 (PF01434, IPR000642): Peptidase family M41

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