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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)106
The number (and %) of the onco-proteins24 (22.64 %)
The number (and %) of the tumor suppressors9 (8.49 %)
Total number of binary PPIs (saturation %)444 (7.98 %)
The number (and %) of affected PPIs105 (23.65 %)
The number of possible different fusions19
PPI diameter5
PPI radius3
The average degree of PPI7.849
Assortativity coefficient-0.4214
The network average Clustering coefficient0.293
The number (and %) of a zero Clustering coefficients33 (31.13 %)
The number (and %) of a zero Betweenness Centrality23 (21.70 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: RIOK1,MME All fusions
Proteins found in more fusions IMPDH2 (see 1 fusions); RBFOX2 (see 3 fusions); MME (see 1 fusions); APP (see 5 fusions); LMNA (see 4 fusions); RUVBL1 (see 1 fusions); PRMT5 (see 1 fusions); LYN (see 2 fusions); GAN (see 1 fusions); EEF1A1 (see 6 fusions); EGFR (see 2 fusions); HSPB1 (see 1 fusions); CSNK2A1 (see 2 fusions); PCNA (see 1 fusions); SLC9A3R1 (see 2 fusions); FECH (see 2 fusions); SNW1 (see 1 fusions); UTRN (see 4 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 RIOK1parental protein290.1871077.797RIO1 (PF01163, IPR018934): RIO1 family
2 MMEparental protein760.0235997.348Peptidase_M13 (PF01431, IPR018497): Peptidase family M13
Peptidase_M13_N (PF05649, IPR008753): Peptidase family M13
3 AGTinteractor100Nuc_rec_co-act (PF08815, IPR014920): Nuclear receptor coactivator
Serpin (PF00079, IPR023796, SM00093): Serpin (serine protease inhibitor)
4 ALDH3A2interactor30.3333.961Aldedh (PF00171, IPR015590): Aldehyde dehydrogenase family
5 APPprotein found in more fusions180.162170.189APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding
Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP)
BUD22 (PF09073, IPR015158): BUD22
IncA (PF04156, IPR007285): IncA protein
Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus
APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
6 ARL1interactor30.3334.162Arf (PF00025, IPR006689, SM00177): ADP-ribosylation factor family
7 ARMC10suppressor100Arm_2 (PF04826, IPR006911): Armadillo-like
8 ATP12Ainteractor203.645Cation_ATPase_C (PF00689, IPR006068): Cation transporting ATPase, C-terminus
Cation_ATPase_N (PF00690, IPR004014, SM00831): Cation transporter/ATPase, N-terminus
E1-E2_ATPase (PF00122, IPR008250): E1-E2 ATPase
FA_desaturase (PF00487, IPR005804): Fatty acid desaturase
Hydrolase (PF00702, IPR023214): haloacid dehalogenase-like hydrolase
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
HAD (PF12710): haloacid dehalogenase-like hydrolase
Cation_ATPase (PF13246): Cation transport ATPase (P-type)
9 ATP5J2interactor100WRW (PF10206, IPR019344): Mitochondrial F1F0-ATP synthase, subunit f
10 CD4suppressor60.4005.469ATP1G1_PLM_MAT8 (PF02038, IPR000272): ATP1G1/PLM/MAT8 family
C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain
CD4-extracel (PF09191, IPR015274): CD4, extracellular
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
Tcell_CD4_C (PF12104, IPR021963): T cell CD4 receptor C terminal region
11 CDK5RAP3interactor50.7003.816DUF773 (PF05600, IPR008491): Protein of unknown function (DUF773)
12 CLEC4Minteractor200Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
Lectin_C (PF00059, IPR001304, SM00034): Lectin C-type domain
DUF2730 (PF10805, IPR020269): Protein of unknown function (DUF2730)
13 CPSF6interactor70.42933.686RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
PRIMA1 (PF16101): Proline-rich membrane anchor 1
14 CSNK2A1oncoprotein150.33086.848Pkinase (PF00069, IPR000719): Protein kinase domain
15 DNAJB12interactor30.6673.244DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DUF1977 (PF09320, IPR015399): Domain of unknown function (DUF1977)
TPR_19 (PF14559): Tetratricopeptide repeat
16 EEF1A1suppressor220.338197.878GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain
17 EGFRoncoprotein260.183372.153Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT)
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
18 EIF4A3interactor160.429110.489DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
19 ELAVL1oncoprotein240.130465.072RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
20 EMC2interactor60.46741.286TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
TPR_8 (PF13181, IPR019734): Tetratricopeptide repeat
TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_19 (PF14559): Tetratricopeptide repeat
Alkyl_sulf_dimr (PF14863, IPR029228): Alkyl sulfatase dimerisation
21 FAAHinteractor100Amidase (PF01425, IPR000120): Amidase
22 FAHD1interactor100FAA_hydrolase (PF01557, IPR002529): Fumarylacetoacetate (FAA) hydrolase family
23 FAM177A1interactor100Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
Connexin (PF00029, IPR013092, SM00037): Connexin
FAM177 (PF14774, IPR028260): FAM177 family
24 FAM234Ainteractor205.160FG-GAP (PF01839, IPR013517): FG-GAP repeat
PQQ_2 (PF13360, IPR002372): PQQ-like domain
VCBS (PF13517): Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella
25 FAM83Finteractor205.277DUF1669 (PF07894, IPR012461): Protein of unknown function (DUF1669)
26 FBLinteractor140.44060.120Fibrillarin (PF01269, IPR000692): Fibrillarin
27 FBXO6interactor210.143282.732FBA (PF04300, IPR007397): F-box associated region
F-box-like (PF12937, IPR001810): F-box-like
28 FBXW7suppressor60.7003.884Mem_trans (PF03547, IPR004776): Membrane transport protein
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
F-box-like (PF12937, IPR001810): F-box-like
29 FECHprotein found in more fusions4011.420Ferrochelatase (PF00762, IPR001015): Ferrochelatase
30 FLOT2interactor40.5009.464YjbH (PF06082, IPR010344): Exopolysaccharide biosynthesis protein YbjH
Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family
Flot (PF15975, IPR031905): Flotillin
31 FOLH1interactor100PA (PF02225, IPR003137): PA domain
Peptidase_M28 (PF04389, IPR007484): Peptidase family M28
TFR_dimer (PF04253, IPR007365): Transferrin receptor-like dimerisation domain
UNC-79 (PF14776): Cation-channel complex subunit UNC-79
32 GANprotein found in more fusions110.13350.720BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
Kelch_3 (PF13415): Galactose oxidase, central domain
Kelch_5 (PF13854): Kelch motif
33 GAR1interactor40.5009.301Gar1 (PF04410, IPR007504): Gar1/Naf1 RNA binding region
34 HDAC8interactor21.0000DNase-RNase (PF02577, IPR003729): Bifunctional nuclease
Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
35 HIST1H2AGinteractor208.740Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
36 HSPA1Ainteractor130.372115.623HSP70 (PF00012, IPR013126): Hsp70 protein
37 HSPA4interactor130.38593.620Herpes_ICP4_N (PF03584, IPR005206): Herpesvirus ICP4-like protein N-terminal region
HSP70 (PF00012, IPR013126): Hsp70 protein
TP53IP5 (PF15331, IPR029290): Cellular tumour antigen p53-inducible 5
38 HSPA8oncoprotein210.271365.676HSP70 (PF00012, IPR013126): Hsp70 protein
39 HSPB1oncoprotein140.43673.523HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family
40 IMPDH2protein found in more fusions50.33336.753IMPDH (PF00478, IPR001093): IMP dehydrogenase / GMP reductase domain
41 INPP5Dinteractor21.0000Exo_endo_phos (PF03372, IPR005135): Endonuclease/Exonuclease/phosphatase family
SH2 (PF00017, IPR000980, SM00252): SH2 domain
42 IRAK2oncoprotein100Death (PF00531, IPR000488, SM00005): Death domain
Pkinase (PF00069, IPR000719): Protein kinase domain
43 KBTBD3interactor100BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
Kelch_6 (PF13964): Kelch motif
44 KRT10interactor60.13362.290Filament (PF00038, IPR001664): Intermediate filament protein
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
45 LAMTOR1interactor40.3337.453LAMTOR (PF15454, IPR028209): Late endosomal/lysosomal adaptor and MAPK and MTOR activator
46 LMNAprotein found in more fusions90.39333.740Filament (PF00038, IPR001664): Intermediate filament protein
LTD (PF00932, IPR001322): Lamin Tail Domain
Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
47 LONP1interactor30.3336.889AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
AAA_PrkA (PF08298, IPR013153, SM00763): PrkA AAA domain
LON_substr_bdg (PF02190, IPR003111, SM00464): ATP-dependent protease La (LON) substrate-binding domain
Lon_C (PF05362, IPR008269): Lon protease (S16) C-terminal proteolytic domain
RuvB_N (PF05496, IPR008824): Holliday junction DNA helicase ruvB N-terminus
AAA_23 (PF13476): AAA domain
48 LYNoncoprotein80.33355.715Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
49 MAGOHinteractor130.38545.063Mago_nashi (PF02792, IPR004023): Mago nashi protein
50 MED20interactor60.60020.695Med20 (PF08612, IPR013921): TATA-binding related factor (TRF) of subunit 20 of Mediator complex
51 MED23interactor70.61944.167Med23 (PF11573, IPR021629): Mediator complex subunit 23
52 MED4interactor60.60039.007Med4 (PF10018, IPR019258): Vitamin-D-receptor interacting Mediator subunit 4
53 METTL7Ainteractor205.277Methyltransf_11 (PF08241, IPR013216): Methyltransferase domain
54 MRPL44interactor203.645dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
Ribonuclease_3 (PF00636, IPR000999, SM00535): Ribonuclease III domain
55 MRPS25interactor21.0000L51_S25_CI-B8 (PF05047, IPR007741, SM00916): Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain
56 MRVI1suppressor100MRVI1 (PF05781, IPR008677): MRVI1 protein
57 MTDHinteractor40.6674.195NST1 (PF13945, IPR025279): Salt tolerance down-regulator
NAM-associated (PF14303, IPR029466): No apical meristem-associated C-terminal domain
LYRIC (PF15686, IPR031402): Lysine-rich CEACAM1 co-isolated protein family
58 MTHFD1interactor4026.650FTHFS (PF01268, IPR000559): Formate--tetrahydrofolate ligase
THF_DHG_CYH (PF00763, IPR020630): Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain
THF_DHG_CYH_C (PF02882, IPR020631): Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain
59 MYH9suppressor90.41759.503IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain
Myosin_tail_1 (PF01576, IPR002928): Myosin tail
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
60 NDRG1suppressor40.5006.146Ndr (PF03096, IPR004142): Ndr family
61 NDUFA10interactor30.6673.645dNK (PF01712, IPR002624): Deoxynucleoside kinase
62 NDUFA9interactor100.35670.468Epimerase (PF01370, IPR001509): NAD dependent epimerase/dehydratase family
63 NDUFB4interactor21.0000NDUF_B4 (PF07225, IPR009866): NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4)
64 NNTinteractor30.6673.645AlaDh_PNT_C (PF01262, IPR007698, SM01002): Alanine dehydrogenase/PNT, C-terminal domain
AlaDh_PNT_N (PF05222, IPR007886, SM01003): Alanine dehydrogenase/PNT, N-terminal domain
PNTB (PF02233, IPR012136): NAD(P) transhydrogenase beta subunit
PNTB_4TM (PF12769, IPR024605): 4TM region of pyridine nucleotide transhydrogenase, mitoch
65 NOLC1interactor70.38134.475DTHCT (PF08070, IPR012542): DTHCT (NUC029) region
SRP40_C (PF05022, IPR007718): SRP40, C-terminal domain
Stm1_N (PF09598, IPR019084): Stm1
stn_TNFRSF12A (PF12191, IPR022316): Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain
NST1 (PF13945, IPR025279): Salt tolerance down-regulator
SEEEED (PF14797, IPR029394): Serine-rich region of AP3B1, clathrin-adaptor complex
DUF4611 (PF15387, IPR027893): Domain of unknown function (DUF4611)
PAF (PF15715, IPR031444): PCNA-associated factor
IMUP (PF15761, IPR026621): Immortalisation up-regulated protein
NuDC (PF16273, IPR032572): Nuclear distribution C domain
PHC2_SAM_assoc (PF16616): Unstructured region on Polyhomeotic-like protein 1 and 2
66 NPPAinteractor100ANP (PF00212, IPR000663, SM00183): Atrial natriuretic peptide
67 NTRK1oncoprotein450.1271270.103I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
68 NUCKS1interactor205.277FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid)
XRCC4 (PF06632, IPR010585): DNA double-strand break repair and V(D)J recombination protein XRCC4
PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
CCSAP (PF15748, IPR029774): Centriole, cilia and spindle-associated
69 OPA1interactor60.46722.061DUF1593 (PF07632, IPR011483): Protein of unknown function (DUF1593)
Ephrin_rec_like (PF07699, IPR011641): Putative ephrin-receptor like
IncA (PF04156, IPR007285): IncA protein
Ras (PF00071, IPR001806, SM00173): Ras family
Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family
DUF4061 (PF13270, IPR025271): Domain of unknown function (DUF4061)
70 PAN2interactor170.199135.628RNase_T (PF00929, IPR013520): Exonuclease
UCH_1 (PF13423, IPR001394): Ubiquitin carboxyl-terminal hydrolase
WD40_like (PF17005, IPR031544): WD40-like domain
71 PCNAoncoprotein90.50046.277PCNA_C (PF02747, IPR022649): Proliferating cell nuclear antigen, C-terminal domain
PCNA_N (PF00705, IPR022648): Proliferating cell nuclear antigen, N-terminal domain
72 PDIA5interactor100Thioredoxin (PF00085, IPR013766): Thioredoxin
Thioredoxin_6 (PF13848): Thioredoxin-like domain
73 PLPPR1interactor100PAP2 (PF01569, IPR000326, SM00014): PAP2 superfamily
74 POC1Ainteractor202.130WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
75 POTEIinteractor100Actin (PF00022, IPR004000, SM00268): Actin
PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID)
DUF3641 (PF12345, IPR024521): Protein of unknown function (DUF3641)
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
CCDC144C (PF14915): CCDC144C protein coiled-coil region
76 PRMT5protein found in more fusions150.330112.708PRMT5 (PF05185, IPR025799): PRMT5 arginine-N-methyltransferase
77 RAP2Boncoprotein100Ras (PF00071, IPR001806, SM00173): Ras family
78 RBFOX2protein found in more fusions50.8332.654RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Fox-1_C (PF12414, IPR025670): Calcitonin gene-related peptide regulator C terminal
79 RBM39oncoprotein90.36150.388RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
RBM39linker (PF15519, IPR029123): linker between RRM2 and RRM3 domains in RBM39 protein
80 RGPD6interactor100GRIP (PF01465, IPR000237, SM00755): GRIP domain
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
Ran_BP1 (PF00638, IPR000156, SM00160): RanBP1 domain
TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_12 (PF13424): Tetratricopeptide repeat
FlxA (PF14282, IPR025577): FlxA-like protein
TPR_19 (PF14559): Tetratricopeptide repeat
Rab_bind (PF16704, IPR032023): Rab binding domain
81 RPL30interactor80.57134.186NCBP3 (PF10309, IPR019416): Nuclear cap-binding protein subunit 3
82 RPS10interactor130.231191.970S10_plectin (PF03501, IPR005326): Plectin/S10 domain
83 RPS2interactor160.342115.696Ribosomal_S5 (PF00333, IPR013810): Ribosomal protein S5, N-terminal domain
Ribosomal_S5_C (PF03719, IPR005324): Ribosomal protein S5, C-terminal domain
84 RPS23interactor80.57125.296Ribosom_S12_S23 (PF00164, IPR006032): Ribosomal protein S12/S23
85 RUVBL1oncoprotein150.42975.544TIP49 (PF06068, IPR010339): TIP49 C-terminus
86 RUVBL2oncoprotein140.37289.415TIP49 (PF06068, IPR010339): TIP49 C-terminus
87 SDF4interactor205.820Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region
EF-hand_1 (PF00036, IPR002048, SM00054): EF hand
EF-hand_5 (PF13202, IPR002048): EF hand
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
88 SLC16A1oncoprotein203.645MFS_1 (PF07690, IPR011701): Major Facilitator Superfamily
89 SLC9A3R1suppressor40.33319.325EBP50_C (PF09007, IPR015098): EBP50, C-terminal
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
90 SMURF1interactor120.21849.437C2 (PF00168, IPR000008, SM00239): C2 domain
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
91 SNW1protein found in more fusions170.35085.014SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
SIR4_SID (PF16991, IPR031556): Sir4 SID domain
92 SRSF11interactor70.61911.853Rtf2 (PF04641, IPR027799): Rtf2 RING-finger
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
TP2 (PF01254, IPR000678): Nuclear transition protein 2
Transformer (PF06495, IPR010519): Fruit fly transformer protein
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
93 SSR4interactor40.16718.451TRAP-delta (PF05404, IPR008855): Translocon-associated protein, delta subunit precursor (TRAP-delta)
OppC_N (PF12911, IPR025966): N-terminal TM domain of oligopeptide transport permease C
94 TINAGL1interactor21.0000Pacifastin_I (PF05375, IPR008037): Pacifastin inhibitor (LCMII)
Peptidase_C1 (PF00112, IPR000668, SM00645): Papain family cysteine protease
Propeptide_C1 (PF08127, IPR012599): Peptidase family C1 propeptide
Somatomedin_B (PF01033, IPR001212, SM00201): Somatomedin B domain
95 TM9SF1interactor100EMP70 (PF02990, IPR004240): Endomembrane protein 70
96 TNPO1interactor50.20092.808Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
HEAT (PF02985, IPR000357): HEAT repeat
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
DUF3437 (PF11919, IPR021843): Domain of unknown function (DUF3437)
MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
97 TUBB8interactor50.10041.626Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
98 UBAC2interactor2027.513Rhomboid (PF01694, IPR022764): Rhomboid family
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
99 UBL4Ainteractor150.238106.217ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
100 UTRNprotein found in more fusions3064.652bZIP_1 (PF00170, IPR004827): bZIP transcription factor
CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1
EF-hand_2 (PF09068, IPR015153): EF hand
EF-hand_3 (PF09069, IPR015154): EF-hand
Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
Spectrin (PF00435, IPR002017): Spectrin repeat
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
WW (PF00397, IPR001202, SM00456): WW domain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion
CCDC-167 (PF15188, IPR028194): Coiled-coil domain-containing protein 167
ABC_tran_CTD (PF16326, IPR032524): ABC transporter C-terminal domain
101 VDAC2interactor90.278104.888Porin_3 (PF01459, IPR027246): Eukaryotic porin
102 WDR77oncoprotein140.34659.663LT-IIB (PF06453, IPR010503): Type II heat-labile enterotoxin , B subunit (LT-IIB)
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
103 XPO1interactor170.265131.300CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
104 XRCC5suppressor110.42237.410Ku (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain
Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm
Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain
Ku_PK_bind (PF08785, IPR014893): Ku C terminal domain like
105 YWHABinteractor90.44434.04214-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
Virulence_fact (PF13769, IPR025989): Virulence factor
106 ZMPSTE24interactor205.277Peptidase_M48 (PF01435, IPR001915): Peptidase family M48
Peptidase_M48_N (PF16491, IPR032456): CAAX prenyl protease N-terminal, five membrane helices

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