Find Fusion Network

Visualization interactions

Powered by Cytoscape Web for: parental proteins FAF2, BCAR4 (from a repository: Sun Jul 28 21:11:54 2019)

Examples AFF1 MLL ACTN4 + MLLAFF1 + MLLALK + MSNALK + TFGALK + TPM3ALK + TPM4ASXL2 + KAT6AATF1 + FUSBCR + ABL1BCR + FGFR1CCND1 + TACSTD2CD74 + ROS1CDK6 + MLLCOL1A1 + PDGFBCREB3L2 + PPARGCREB3L2 + FUSCREBBP + KAT6ADAZAP1 + MEF2DELL + MLLEPS15 + MLLERG + EWSR1ERG + FUSERG + TMPRSS2ETV5 + TMPRSS2ETV6 + ABL1ETV6 + NTRK3ETV6 + PAX5EWSR1 + FLI1EWSR1 + WT1FOXO1 + PAX3FOXP1 + PAX5FRYL + MLLGAS7 + MLLGMPS + MLLGOLGA5 + RETHOOK3 + RETHOXC13 + NUP98HOXD13 + NUP98MECOM + RUNX1MKL1 + RBM15MLL + MLLT1MLL + MLLT4MLL + MLLT10MLL + PICALMMLLT10 + PICALMNCOA1 + PAX3NIN + PDGFRBNPM1 + RARANRG1 + ODZ4NTRK1 + TFGNUMA1 + RARANUP98 + PHF23PAX5 + ZNF521PBX1 + TCF3RET + TRIM27ROS1 + SLC34A2PML + RARAPRKAR1A + RARAPRKAR1A + RETRUNX1 + RUNX1T1RUNX1 + SH3D19	Cytoscape Web will replace the contents your graph	PPI Properties: Click on nodes or edges
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Statistics and Network structure information

Statistic of PPI Value(s) The number of interactors (fusion and proteins) 236 The number (and %) of the onco-proteins 53 (22.46 %) The number (and %) of the tumor suppressors 12 (5.08 %) Total number of binary PPIs (saturation %) 1253 (4.52 %) The number (and %) of affected PPIs 235 (18.75 %) The number of possible different fusions 36 PPI diameter 2 PPI radius inf The average degree of PPI 10.136 Assortativity coefficient -0.2859 The network average Clustering coefficient 0.507 The number (and %) of a zero Clustering coefficients 22 (9.32 %) The number (and %) of a zero Betweenness Centrality 55 (23.31 %)

ACTIVE INTERACTORS

List of the fusions
PPI for parental proteins: BCAR4,FAF2	All fusions
Proteins found in more fusions	TUBG1 (see 1 fusions); HLA-B (see 4 fusions); FAF2/SARAF (see 1 fusions); CUL1 (see 3 fusions); CUL3 (see 1 fusions); S100A10 (see 1 fusions); LGALS3BP (see 2 fusions); MAP3K1 (see 1 fusions); UBE3A (see 1 fusions); OXA1L (see 1 fusions); PRKDC (see 2 fusions); UBE3C (see 1 fusions); ACTG1 (see 5 fusions); PJA2 (see 1 fusions); OS9 (see 2 fusions); UBC (see 7 fusions); MSH2 (see 1 fusions); MAGED1 (see 1 fusions); SYVN1 (see 1 fusions); VCP (see 4 fusions); PFKL (see 2 fusions); ACTN1 (see 3 fusions); HUWE1 (see 4 fusions); HLA-B/HLA-C (see 4 fusions); STOM (see 1 fusions); INSIG1 (see 1 fusions); EGFR (see 2 fusions); MCM2 (see 1 fusions); UBR5 (see 4 fusions); UBQLN2 (see 3 fusions); TUBA1B/TUBA1A (see 2 fusions); HLA-C (see 1 fusions); TUBA1B/TUBA1C (see 11 fusions); DDB1 (see 4 fusions); RPTOR (see 3 fusions);

List of active interactors

#	Name	Type	Number of PPI (degree)	Clustering Coefficient	Betweenness Centrality	Domains (Pfam, InterPro, SMART): description
1	BCAR4	oncoprotein	0	0	0	NA
2	FAF2	parental protein	235	0.035	42812.294	DUF1682 (PF07946, IPR012879): Protein of unknown function (DUF1682) UBX (PF00789, IPR001012, SM00166): UBX domain Thioredoxin_7 (PF13899): Thioredoxin-like UBA_4 (PF14555): UBA-like domain
3	ABCB7	interactor	2	1.000	0	ABC_membrane (PF00664, IPR001140): ABC transporter transmembrane region ABC_tran (PF00005, IPR003439): ABC transporter SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain AAA_23 (PF13476): AAA domain
4	ABCD3	interactor	9	0.278	16.752	ABC_membrane_2 (PF06472, IPR010509): ABC transporter transmembrane region 2 ABC_tran (PF00005, IPR003439): ABC transporter
5	ABCF2	interactor	5	0.600	3.000	ABC_tran (PF00005, IPR003439): ABC transporter VIT1 (PF01988, IPR008217): VIT family Rop (PF01815, IPR000769): Rop protein ABC_tran_Xtn (PF12848, IPR032781): ABC transporter AAA_21 (PF13304, IPR003959): AAA domain, putative AbiEii toxin, Type IV TA system
6	ABHD17B	interactor	1	0	0	Peptidase_S9 (PF00326, IPR001375): Prolyl oligopeptidase family Hydrolase_4 (PF12146, IPR022742): Serine aminopeptidase, S33
7	ACAD9	interactor	7	0.619	6.333	Acyl-CoA_dh_1 (PF00441, IPR009075): Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M (PF02770, IPR006091): Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N (PF02771, IPR013786): Acyl-CoA dehydrogenase, N-terminal domain
8	ACADM	oncoprotein	9	0.444	13.983	Acyl-CoA_dh_1 (PF00441, IPR009075): Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M (PF02770, IPR006091): Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N (PF02771, IPR013786): Acyl-CoA dehydrogenase, N-terminal domain
9	ACADSB	interactor	3	0.667	0.250	Acyl-CoA_dh_1 (PF00441, IPR009075): Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M (PF02770, IPR006091): Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N (PF02771, IPR013786): Acyl-CoA dehydrogenase, N-terminal domain
10	ACTG1	protein found in more fusions	8	0.429	5.400	Actin (PF00022, IPR004000, SM00268): Actin
11	ACTG2	interactor	4	0.667	0.633	Actin (PF00022, IPR004000, SM00268): Actin
12	ACTN1	protein found in more fusions	7	0.533	5.167	CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain Dak2 (PF02734, IPR004007, SM01120): DAK2 domain EFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand Spectrin (PF00435, IPR002017): Spectrin repeat EF-hand_7 (PF13499, IPR011992): EF-hand domain pair Uds1 (PF15456, IPR029191): Up-regulated During Septation
13	ACTR5	interactor	4	0.500	3.000	Actin (PF00022, IPR004000, SM00268): Actin DUF1542 (PF07564, IPR011439): Domain of Unknown Function (DUF1542) UPF0449 (PF15136, IPR028227): Uncharacterised protein family UPF0449
14	AHCTF1	interactor	2	1.000	0	AT_hook (PF02178, IPR017956, SM00384): AT hook motif DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) DUF702 (PF05142, IPR007818): Domain of unknown function (DUF702) ELYS (PF13934, IPR025151): Nuclear pore complex assembly ELYS-bb (PF16687, IPR032040): beta-propeller of ELYS nucleoporin
15	ALDH1B1	interactor	7	0.476	5.318	Aldedh (PF00171, IPR015590): Aldehyde dehydrogenase family
16	ALDH3A2	interactor	9	0.389	12.710	Aldedh (PF00171, IPR015590): Aldehyde dehydrogenase family
17	ALPP	interactor	5	0.500	1.738	Alk_phosphatase (PF00245, IPR001952, SM00098): Alkaline phosphatase
18	AMFR	oncoprotein	32	0.331	151.812	CUE (PF02845, IPR003892, SM00546): CUE domain UbiA (PF01040, IPR000537): UbiA prenyltransferase family zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
19	APOB	interactor	10	0.667	3.516	DUF1081 (PF06448, IPR009454): Domain of Unknown Function (DUF1081) DUF1943 (PF09172, IPR015255, SM01169): Domain of unknown function (DUF1943) Phage_holin_6_1 (PF09682, IPR010026): Bacteriophage holin of superfamily 6 (Holin_LLH) Vitellogenin_N (PF01347, IPR001747, SM00638): Lipoprotein amino terminal region DUF2807 (PF10988, IPR021255): Putative auto-transporter adhesin, head GIN domain ApoB100_C (PF12491, IPR022176): Apolipoprotein B100 C terminal
20	ARAF	oncoprotein	10	0.400	13.009	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase RBD (PF02196, IPR003116, SM00455): Raf-like Ras-binding domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
21	ARF3	interactor	2	1.000	0	Arf (PF00025, IPR006689, SM00177): ADP-ribosylation factor family
22	ARF5	interactor	6	0.533	5.067	Arf (PF00025, IPR006689, SM00177): ADP-ribosylation factor family
23	ARL14EP	interactor	1	0	0	ARF7EP_C (PF14949, IPR029264): ARF7 effector protein C-terminus
24	ARL6IP1	interactor	4	0.667	1.000	Reticulon (PF02453, IPR003388): Reticulon TraG_N (PF07916, IPR012931): TraG-like protein, N-terminal region
25	ATAD1	interactor	4	0.500	1.139	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) PhoH (PF02562, IPR003714): PhoH-like protein DUF3240 (PF11582, IPR021634): Protein of unknown function (DUF3240) AAA_18 (PF13238): AAA domain
26	ATG9A	interactor	2	1.000	0	APG9 (PF04109, IPR007241): Autophagy protein Apg9 PRRSV_2b (PF07069, IPR009775): Porcine reproductive and respiratory syndrome virus 2b
27	ATP2B3	interactor	2	1.000	0	Cation_ATPase_C (PF00689, IPR006068): Cation transporting ATPase, C-terminus Cation_ATPase_N (PF00690, IPR004014, SM00831): Cation transporter/ATPase, N-terminus E1-E2_ATPase (PF00122, IPR008250): E1-E2 ATPase Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase ATP_Ca_trans_C (PF12424, IPR022141): Plasma membrane calcium transporter ATPase C terminal Cation_ATPase (PF13246): Cation transport ATPase (P-type)
28	ATP2C1	interactor	4	0.667	1.400	Cation_ATPase_C (PF00689, IPR006068): Cation transporting ATPase, C-terminus Cation_ATPase_N (PF00690, IPR004014, SM00831): Cation transporter/ATPase, N-terminus E1-E2_ATPase (PF00122, IPR008250): E1-E2 ATPase Hydrolase (PF00702, IPR023214): haloacid dehalogenase-like hydrolase Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase YoqO (PF14037, IPR025621): YoqO-like protein
29	ATP4A	interactor	5	0.667	2.000	Cation_ATPase_C (PF00689, IPR006068): Cation transporting ATPase, C-terminus Cation_ATPase_N (PF00690, IPR004014, SM00831): Cation transporter/ATPase, N-terminus E1-E2_ATPase (PF00122, IPR008250): E1-E2 ATPase H-K_ATPase_N (PF09040, IPR015127): Gastric H+/K+-ATPase, N terminal domain Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase HAD (PF12710): haloacid dehalogenase-like hydrolase Cation_ATPase (PF13246): Cation transport ATPase (P-type)
30	ATP5B	interactor	18	0.301	66.338	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain NACHT (PF05729): NACHT domain
31	ATP6V1H	interactor	4	0.667	0.619	V-ATPase_H_N (PF03224, IPR004908): V-ATPase subunit H V-ATPase_H_C (PF11698, IPR011987): V-ATPase subunit H
32	AUP1	interactor	17	0.375	44.339	CUE (PF02845, IPR003892, SM00546): CUE domain
33	BAG6	interactor	25	0.236	157.344	DUF1179 (PF06678, IPR009564): Protein of unknown function (DUF1179) Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family DUF2939 (PF11159, IPR021330): Protein of unknown function (DUF2939) DUF3538 (PF12057, IPR021925): Domain of unknown function (DUF3538) PRIMA1 (PF16101): Proline-rich membrane anchor 1
34	BCKDHB	interactor	2	1.000	0	Transket_pyr (PF02779, IPR005475, SM00861): Transketolase, pyrimidine binding domain Transketolase_C (PF02780, IPR005476): Transketolase, C-terminal domain
35	C19orf52	interactor	2	1.000	0	DUF2366 (PF10171, IPR019322): Uncharacterised conserved protein (DUF2366)
36	CALU	interactor	12	0.424	23.013	EF-hand_6 (PF13405, IPR002048): EF-hand domain EF-hand_7 (PF13499, IPR011992): EF-hand domain pair EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
37	CAND1	interactor	25	0.301	106.767	Adaptin_N (PF01602, IPR002553): Adaptin N terminal region DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981) HEAT (PF02985, IPR000357): HEAT repeat TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20) RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II
38	CAV1	suppressor	15	0.305	58.317	Caveolin (PF01146, IPR001612): Caveolin
39	CBR1	interactor	4	0.833	0.286	adh_short (PF00106, IPR002198): short chain dehydrogenase
40	CDKAL1	interactor	3	1.000	0	Radical_SAM (PF04055, IPR007197): Radical SAM superfamily TRAM (PF01938, IPR002792): TRAM domain UPF0004 (PF00919, IPR013848): Uncharacterized protein family UPF0004
41	CDKN2AIP	interactor	4	1.000	0	XTBD (PF11952, IPR021859): XRN-Two Binding Domain, XTBD
42	CLEC11A	interactor	1	0	0	ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) HBS1_N (PF08938, IPR015033): HBS1 N-terminus Lectin_C (PF00059, IPR001304, SM00034): Lectin C-type domain
43	COX4I1	interactor	7	0.619	4.650	COX4 (PF02936, IPR004203): Cytochrome c oxidase subunit IV
44	CSE1L	oncoprotein	14	0.385	26.706	CAS_CSE1 (PF03378, IPR005043): CAS/CSE protein, C-terminus Cse1 (PF08506, IPR013713): Cse1 IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain Xpo1 (PF08389, IPR013598): Exportin 1-like protein
45	CUL1	suppressor	20	0.415	44.717	Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
46	CUL2	suppressor	24	0.304	104.757	Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
47	CUL3	protein found in more fusions	52	0.140	807.860	Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
48	DAGLB	interactor	1	0	0	Lipase_3 (PF01764, IPR002921): Lipase (class 3)
49	DCAF7	interactor	5	0.500	2.472	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
50	DDB1	protein found in more fusions	14	0.423	32.853	CPSF_A (PF03178, IPR004871): CPSF A subunit region MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term
51	DERL1	interactor	24	0.285	114.054	DER1 (PF04511, IPR007599): Der1-like family
52	DERL2	interactor	15	0.438	34.808	DER1 (PF04511, IPR007599): Der1-like family
53	DMXL2	interactor	1	0	0	eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Rav1p_C (PF12234, IPR022033): RAVE protein 1 C terminal ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
54	DNAJB1	suppressor	10	0.400	18.721	DnaJ (PF00226, IPR001623, SM00271): DnaJ domain DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
55	ECE1	interactor	2	1.000	0	Peptidase_M13 (PF01431, IPR018497): Peptidase family M13 Peptidase_M13_N (PF05649, IPR008753): Peptidase family M13
56	ECSIT	interactor	14	0.269	52.500	ECSIT (PF06239, IPR010418): Evolutionarily conserved signalling intermediate in Toll pathway ECSIT_C (PF14784, IPR029342): C-terminal domain of the ECSIT protein
57	EGFR	oncoprotein	50	0.105	818.360	Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT) GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
58	ELAVL1	oncoprotein	50	0.081	941.686	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
59	EMC1	interactor	10	0.333	14.829	DUF1620 (PF07774, IPR011678): Protein of unknown function (DUF1620) PQQ (PF01011, IPR002372, SM00564): PQQ enzyme repeat PQQ_2 (PF13360, IPR002372): PQQ-like domain
60	EMD	interactor	17	0.342	42.435	LEM (PF03020, IPR003887, SM00540): LEM domain SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
61	ENO1	oncoprotein	12	0.379	17.613	Enolase_C (PF00113, IPR020810): Enolase, C-terminal TIM barrel domain Enolase_N (PF03952, IPR020811): Enolase, N-terminal domain
62	EPB41L3	suppressor	6	0.467	4.248	4_1_CTD (PF05902, IPR008379): 4.1 protein C-terminal domain (CTD) FA (PF08736, IPR014847): FERM adjacent (FA) FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain FERM_M (PF00373, IPR019748): FERM central domain FERM_N (PF09379, IPR018979): FERM N-terminal domain RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 SAB (PF04382, IPR007477): SAB domain
63	ERGIC1	interactor	2	1.000	0	COPIIcoated_ERV (PF07970, IPR012936): Endoplasmic reticulum vesicle transporter ERGIC_N (PF13850): Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC)
64	ERLIN1	interactor	9	0.611	4.117	Ribosomal_L33 (PF00471, IPR001705): Ribosomal protein L33 Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family DUF4346 (PF14251, IPR025595): Domain of unknown function (DUF4346)
65	ERLIN2	interactor	19	0.392	40.780	Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family DUF4346 (PF14251, IPR025595): Domain of unknown function (DUF4346)
66	ESYT1	interactor	5	0.600	2.567	C2 (PF00168, IPR000008, SM00239): C2 domain SMP_LBD (PF17047, IPR031468): Synaptotagmin-like mitochondrial-lipid-binding domain
67	ESYT2	interactor	4	0.667	1.400	C2 (PF00168, IPR000008, SM00239): C2 domain DUF3720 (PF12517, IPR022195): Protein of unknown function (DUF3720) SMP_LBD (PF17047, IPR031468): Synaptotagmin-like mitochondrial-lipid-binding domain
68	EVI5L	interactor	2	1.000	0	DivIC (PF04977, IPR007060): Septum formation initiator Nnf1 (PF03980, IPR007128): Nnf1 PAP_central (PF04928, IPR007012): Poly(A) polymerase central domain RabGAP-TBC (PF00566, IPR000195, SM00164): Rab-GTPase-TBC domain bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding
69	FAM46A	interactor	3	0.667	0.286	NTP_transf_7 (PF07984, IPR012937, SM01153): Nucleotidyltransferase
70	FAS	suppressor	10	0.333	22.500	Death (PF00531, IPR000488, SM00005): Death domain TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region Stn1_C (PF12659, IPR024263): Telomere capping C-terminal wHTH
71	FBXO6	interactor	56	0.114	1009.808	FBA (PF04300, IPR007397): F-box associated region F-box-like (PF12937, IPR001810): F-box-like
72	FUNDC2	interactor	3	1.000	0	FUN14 (PF04930, IPR007014): FUN14 family
73	GCAT	interactor	4	0.500	1.091	Aminotran_1_2 (PF00155, IPR004839): Aminotransferase class I and II
74	GCDH	interactor	5	0.600	3.167	Acyl-CoA_dh_1 (PF00441, IPR009075): Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M (PF02770, IPR006091): Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N (PF02771, IPR013786): Acyl-CoA dehydrogenase, N-terminal domain
75	GCN1	interactor	11	0.309	21.899	Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat HEAT (PF02985, IPR000357): HEAT repeat CLASP_N (PF12348, IPR024395): CLASP N terminal MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal TFCD_C (PF12612, IPR022577): Tubulin folding cofactor D C terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II
76	GDAP1	interactor	1	0	0	SyrA (PF11089, IPR024239): Exopolysaccharide production repressor GST_C_2 (PF13410): Glutathione S-transferase, C-terminal domain GST_N_3 (PF13417, IPR004045): Glutathione S-transferase, N-terminal domain DUF4296 (PF14129, IPR025381): Domain of unknown function (DUF4296)
77	GET4	interactor	11	0.745	3.983	DUF410 (PF04190, IPR007317): Protein of unknown function (DUF410) Vps39_1 (PF10366, IPR019452): Vacuolar sorting protein 39 domain 1
78	GPD2	interactor	3	0.667	0.500	DAO (PF01266, IPR006076): FAD dependent oxidoreductase EF-hand_7 (PF13499, IPR011992): EF-hand domain pair DAO_C (PF16901, IPR031656): C-terminal domain of alpha-glycerophosphate oxidase
79	HACD3	interactor	6	0.400	3.637	PTPLA (PF04387, IPR007482): Protein tyrosine phosphatase-like protein, PTPLA
80	HAUS2	interactor	8	0.429	10.058	DpnII (PF04556, IPR007637): DpnII restriction endonuclease HAUS2 (PF15003, IPR028346): HAUS augmin-like complex subunit 2
81	HIF1A	suppressor	11	0.382	20.787	Dicty_REP (PF05086, IPR007778): Dictyostelium (Slime Mold) REP protein HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1
82	HLA-B	oncoprotein	7	0.533	5.200	MHC_I (PF00129, IPR001039): Class I Histocompatibility antigen, domains alpha 1 and 2 MHC_I_C (PF06623, IPR010579): MHC_I C-terminus C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
83	HLA-C	protein found in more fusions	9	0.500	10.425	Marek_A (PF02124, IPR001038): Marek's disease glycoprotein A MHC_I (PF00129, IPR001039): Class I Histocompatibility antigen, domains alpha 1 and 2 MHC_I_C (PF06623, IPR010579): MHC_I C-terminus C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
84	HLA-G	interactor	3	1.000	0	MHC_I (PF00129, IPR001039): Class I Histocompatibility antigen, domains alpha 1 and 2 SNO (PF01174, IPR002161): SNO glutamine amidotransferase family C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
85	HMGCR	oncoprotein	9	0.722	3.296	HMG-CoA_red (PF00368, IPR002202): Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing (PF12349, IPR000731): Sterol-sensing domain of SREBP cleavage-activation
86	HSP90B1	suppressor	26	0.311	122.408	CobT (PF06213, IPR006538): Cobalamin biosynthesis protein CobT HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein Sigma70_ner (PF04546, IPR007631): Sigma-70, non-essential region
87	HSPA5	oncoprotein	39	0.250	305.209	HSP70 (PF00012, IPR013126): Hsp70 protein
88	HUWE1	oncoprotein	30	0.291	160.704	BUD22 (PF09073, IPR015158): BUD22 DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908) DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913) FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM) Mucin (PF01456, IPR000458): Mucin-like glycoprotein Nop14 (PF04147, IPR007276): Nop14-like family PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32 RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain WWE (PF02825, IPR004170, SM00678): WWE domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54 U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414)
89	ILVBL	interactor	7	0.381	5.453	TPP_enzyme_C (PF02775, IPR011766): Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M (PF00205, IPR012000): Thiamine pyrophosphate enzyme, central domain TPP_enzyme_N (PF02776, IPR012001): Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
90	INSIG1	protein found in more fusions	10	0.611	5.881	INSIG (PF07281, IPR025929): Insulin-induced protein (INSIG)
91	INSIG2	interactor	9	0.528	9.330	INSIG (PF07281, IPR025929): Insulin-induced protein (INSIG)
92	INTS3	interactor	5	0.400	5.400	SKA1 (PF07160, IPR009829): Spindle and kinetochore-associated protein 1 Fn_bind (PF02986, IPR004237): Fibronectin binding repeat Ints3 (PF10189, IPR019333): Integrator complex subunit 3
93	INTS4	interactor	3	0.667	1.000	Adaptin_N (PF01602, IPR002553): Adaptin N terminal region HEAT (PF02985, IPR000357): HEAT repeat Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats
94	INTS7	interactor	3	0.667	1.000	DUF3453 (PF11935, IPR021850): Domain of unknown function (DUF3453) TPR_6 (PF13174, IPR019734): Tetratricopeptide repeat HEAT_2 (PF13646): HEAT repeats FANCI_S2 (PF14676, IPR026171): FANCI solenoid 2 SPG48 (PF14764, IPR028222): AP-5 complex subunit, vesicle trafficking
95	IPO9	interactor	6	0.533	4.571	IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain RIX1 (PF08167, IPR012583): rRNA processing/ribosome biogenesis Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein Xpo1 (PF08389, IPR013598): Exportin 1-like protein UNC45-central (PF11701, IPR024660): Myosin-binding striated muscle assembly central HEAT_EZ (PF13513): HEAT-like repeat
96	KIDINS220	interactor	3	1.000	0	KAP_NTPase (PF07693, IPR011646): KAP family P-loop domain SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif) Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_5 (PF13857): Ankyrin repeats (many copies)
97	KRT18	interactor	4	0.667	0.667	Filament (PF00038, IPR001664): Intermediate filament protein Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
98	KRT8	interactor	4	0.500	2.067	Filament (PF00038, IPR001664): Intermediate filament protein Keratin_2_head (PF16208, IPR032444): Keratin type II head
99	LARS	interactor	4	0.500	2.000	Anticodon_1 (PF08264, IPR013155): Anticodon-binding domain of tRNA tRNA-synt_1 (PF00133, IPR002300): tRNA synthetases class I (I, L, M and V)
100	LGALS3BP	oncoprotein	14	0.487	20.124	BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch SRCR (PF00530, IPR001190): Scavenger receptor cysteine-rich domain SRCR_2 (PF15494, IPR017448): Scavenger receptor cysteine-rich domain
101	LPCAT1	interactor	4	0.500	1.952	JmjN (PF02375, IPR003349, SM00545): jmjN domain Acyltransferase (PF01553, IPR002123, SM00563): Acyltransferase EF-hand_6 (PF13405, IPR002048): EF-hand domain EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
102	MAGED1	protein found in more fusions	10	0.444	13.633	MAGE (PF01454, IPR002190): MAGE family
103	MAP3K1	oncoprotein	10	0.472	9.677	zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding Pkinase (PF00069, IPR000719): Protein kinase domain zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain Phostensin_N (PF13916, IPR025903): PP1-regulatory protein, Phostensin N-terminal
104	MCM2	oncoprotein	39	0.168	357.198	AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA) MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2 MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain
105	MCM9	suppressor	2	1.000	0	MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM_OB (PF17207): MCM OB domain
106	MCUB	interactor	2	1.000	0	MCU (PF04678, IPR006769): Mitochondrial calcium uniporter UPF0449 (PF15136, IPR028227): Uncharacterised protein family UPF0449
107	MCUR1	interactor	1	0	0	DUF1640 (PF07798, IPR024461): Protein of unknown function (DUF1640) DUF3708 (PF12501, IPR022182): Phosphate ATP-binding cassette transporter
108	MFN1	interactor	1	0	0	Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus Fzo_mitofusin (PF04799, IPR006884): fzo-like conserved region Tup_N (PF08581, IPR013890): Tup N-terminal Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family YlqD (PF11068, IPR021297): YlqD protein
109	MRPL21	interactor	2	1.000	0	Ribosomal_L21p (PF00829, IPR028909): Ribosomal prokaryotic L21 protein
110	MRPL37	interactor	5	0.600	1.258	PDCD9 (PF07147, IPR010793): Mitochondrial 28S ribosomal protein S30 (PDCD9)
111	MSH2	suppressor	5	0.667	1.067	MutS_I (PF01624, IPR007695): MutS domain I MutS_II (PF05188, IPR007860): MutS domain II MutS_V (PF00488, IPR000432, SM00534): MutS domain V MutS_III (PF05192, IPR007696, SM00533): MutS domain III AAA_27 (PF13514): AAA domain
112	MSH6	oncoprotein	5	0.600	2.500	MutS_I (PF01624, IPR007695): MutS domain I MutS_II (PF05188, IPR007860): MutS domain II PWWP (PF00855, IPR000313, SM00293): PWWP domain MutS_V (PF00488, IPR000432, SM00534): MutS domain V MutS_III (PF05192, IPR007696, SM00533): MutS domain III UPF0524 (PF15823, IPR029670): UPF0524 of C3orf70
113	MT-CO2	interactor	9	0.444	15.369	COX2 (PF00116, IPR002429): Cytochrome C oxidase subunit II, periplasmic domain COX2_TM (PF02790, IPR011759): Cytochrome C oxidase subunit II, transmembrane domain
114	MTHFD1	interactor	10	0.467	11.407	FTHFS (PF01268, IPR000559): Formate--tetrahydrofolate ligase THF_DHG_CYH (PF00763, IPR020630): Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C (PF02882, IPR020631): Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain
115	NDUFAF1	interactor	5	0.900	0.500	CIA30 (PF08547, IPR013857): Complex I intermediate-associated protein 30 (CIA30)
116	NDUFS2	interactor	6	0.533	4.424	Complex1_49kDa (PF00346, IPR001135): Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases (PF00374, IPR001501): Nickel-dependent hydrogenase
117	NF1	suppressor	3	1.000	0	MIF4G_like_2 (PF09090, IPR015174): MIF4G like RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 (PF13716, IPR001251): Divergent CRAL/TRIO domain MOR2-PAG1_C (PF14225, IPR025481): Cell morphogenesis C-terminal
118	NNT	interactor	5	0.500	3.333	AlaDh_PNT_C (PF01262, IPR007698, SM01002): Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N (PF05222, IPR007886, SM01003): Alanine dehydrogenase/PNT, N-terminal domain PNTB (PF02233, IPR012136): NAD(P) transhydrogenase beta subunit PNTB_4TM (PF12769, IPR024605): 4TM region of pyridine nucleotide transhydrogenase, mitoch
119	NOCT	interactor	1	0	0	Exo_endo_phos (PF03372, IPR005135): Endonuclease/Exonuclease/phosphatase family
120	NPEPPS	interactor	4	0.667	0.491	Peptidase_M1 (PF01433, IPR014782): Peptidase family M1 ERAP1_C (PF11838, IPR024571): ERAP1-like C-terminal domain
121	NPLOC4	interactor	23	0.340	96.648	NPL4 (PF05021, IPR007717): NPL4 family zf-NPL4 (PF05020, IPR007716): NPL4 family, putative zinc binding region UN_NPL4 (PF11543, IPR024682): Nuclear pore localisation protein NPL4
122	NUP85	interactor	5	0.700	2.000	Nucleopor_Nup85 (PF07575, IPR011502): Nup85 Nucleoporin
123	OAT	interactor	5	0.800	0.733	Aminotran_3 (PF00202, IPR005814): Aminotransferase class-III
124	ORAI1	interactor	1	0	0	Orai-1 (PF07856, IPR012446): Mediator of CRAC channel activity
125	OS9	protein found in more fusions	16	0.524	22.701	DNA_pol_phi (PF04931, IPR007015): DNA polymerase phi Nucleo_P87 (PF07267, IPR009893): Nucleopolyhedrovirus capsid protein P87 PRKCSH (PF07915, IPR012913): Glucosidase II beta subunit-like protein Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein PRKCSH_1 (PF13015, IPR009011): Glucosidase II beta subunit-like protein
126	OXA1L	protein found in more fusions	4	0.667	0.400	60KD_IMP (PF02096, IPR001708): 60Kd inner membrane protein
127	PCK1	interactor	11	0.273	31.567	PEPCK (PF00821, IPR008209): Phosphoenolpyruvate carboxykinase
128	PEX11B	interactor	3	1.000	0	PEX11 (PF05648, IPR008733): Peroxisomal biogenesis factor 11 (PEX11)
129	PEX19	interactor	8	0.321	11.675	Pex19 (PF04614, IPR006708): Pex19 protein family Rod-binding (PF10135, IPR019301): Rod binding protein
130	PFKL	protein found in more fusions	8	0.619	3.729	PFK (PF00365, IPR000023): Phosphofructokinase
131	PFKP	interactor	8	0.571	3.749	PFK (PF00365, IPR000023): Phosphofructokinase Hrs_helical (PF12210, IPR024641): Hepatocyte growth factor-regulated tyrosine kinase substrate
132	PJA1	interactor	5	0.667	1.000	zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
133	PJA2	protein found in more fusions	9	0.571	5.971	zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding Rad50_zn_hook (PF04423, IPR007517): Rad50 zinc hook motif zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
134	PNPLA2	interactor	1	0	0	Patatin (PF01734, IPR002641): Patatin-like phospholipase
135	PNPLA6	interactor	2	1.000	0	Patatin (PF01734, IPR002641): Patatin-like phospholipase PT (PF04886, IPR006970): PT repeat cNMP_binding (PF00027, IPR000595, SM00100): Cyclic nucleotide-binding domain
136	POLD3	interactor	1	0	0	CDC27 (PF09507, IPR019038): DNA polymerase subunit Cdc27
137	PRKDC	protein found in more fusions	15	0.330	31.206	FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain NUC194 (PF08163, IPR012582): NUC194 domain PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
138	PSEN2	oncoprotein	8	0.381	11.167	Herpes_LMP1 (PF05297, IPR007961): Herpesvirus latent membrane protein 1 (LMP1) Presenilin (PF01080, IPR001108): Presenilin
139	PSMD2	oncoprotein	14	0.264	37.012	PC_rep (PF01851, IPR002015): Proteasome/cyclosome repeat THAP (PF05485, IPR006612, SM00980): THAP domain HEAT_2 (PF13646): HEAT repeats
140	PTGS2	oncoprotein	8	0.714	2.856	An_peroxidase (PF03098, IPR002007): Animal haem peroxidase EGF (PF00008, IPR000742, SM00181): EGF-like domain
141	RAB5C	oncoprotein	10	0.378	21.733	Ras (PF00071, IPR001806, SM00173): Ras family
142	RAB7A	suppressor	19	0.251	93.520	Ras (PF00071, IPR001806, SM00173): Ras family
143	RAB9A	oncoprotein	1	0	0	Ras (PF00071, IPR001806, SM00173): Ras family
144	RBM14-RBM4	interactor	1	0	0	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC (PF00098, IPR001878): Zinc knuckle CompInhib_SCIN (PF11546, IPR021612): Staphylococcal complement inhibitor SCIN ACC_epsilon (PF13822, IPR032716): Acyl-CoA carboxylase epsilon subunit
145	RGS20	interactor	1	0	0	RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain
146	RNF126	interactor	17	0.308	59.796	Rad50_zn_hook (PF04423, IPR007517): Rad50 zinc hook motif zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger zinc_ribbon_9 (PF14369): zinc-ribbon
147	RNF2	interactor	25	0.159	166.781	zf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
148	RPTOR	protein found in more fusions	5	0.500	2.167	HEAT (PF02985, IPR000357): HEAT repeat WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain HEAT_2 (PF13646): HEAT repeats Raptor_N (PF14538, IPR029347): Raptor N-terminal CASPase like domain
149	RRM2	interactor	3	1.000	0	Ribonuc_red_sm (PF00268, IPR000358): Ribonucleotide reductase, small chain
150	S100A10	oncoprotein	4	0.667	1.000	S_100 (PF01023, IPR013787): S-100/ICaBP type calcium binding domain EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
151	SAE1	interactor	3	0.667	0.400	ThiF (PF00899, IPR000594): ThiF family
152	SARAF	protein found in more fusions	6	1.000	0	SARAF (PF06682, IPR009567): SOCE-associated regulatory factor of calcium homoeostasis
153	SEL1L	oncoprotein	13	0.577	12.356	fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain Sel1 (PF08238, IPR006597, SM00671): Sel1 repeat TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
154	SELENOS	interactor	11	0.618	9.167	Selenoprotein_S (PF06936, IPR009703): Selenoprotein S (SelS) DUF3326 (PF11805, IPR021763): Protein of unknown function (DUF3326)
155	SERPINH1	interactor	11	0.364	18.899	Serpin (PF00079, IPR023796, SM00093): Serpin (serine protease inhibitor)
156	SETDB1	interactor	5	0.400	5.667	MBD (PF01429, IPR001739, SM00391): Methyl-CpG binding domain Pre-SET (PF05033, IPR007728): Pre-SET motif SET (PF00856, IPR001214, SM00317): SET domain DUF4537 (PF15057, IPR032770): Domain of unknown function (DUF4537) PNRC (PF15365, IPR028322): Proline-rich nuclear receptor coactivator
157	SLC25A10	interactor	3	0.667	0.143	Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
158	SLC25A16	interactor	2	1.000	0	Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence
159	SLC25A22	interactor	5	0.600	0.767	Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein DUF4257 (PF14074, IPR025353): Protein of unknown function (DUF4257)
160	SLC25A24	interactor	3	0.667	1.000	Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
161	SLC25A4	interactor	4	0.500	2.133	Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
162	SLC26A6	interactor	1	0	0	STAS (PF01740, IPR002645): STAS domain Sulfate_transp (PF00916, IPR011547): Sulfate permease family
163	SORT1	interactor	4	0.500	1.556	Sortilin_C (PF15901, IPR031777): Sortilin, neurotensin receptor 3, C-terminal Sortilin-Vps10 (PF15902, IPR031778): Sortilin, neurotensin receptor 3,
164	SPG7	oncoprotein	1	0	0	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) FtsH_ext (PF06480, IPR011546): FtsH Extracellular Peptidase_M41 (PF01434, IPR000642): Peptidase family M41 AAA_22 (PF13401, IPR003593): AAA domain
165	SQLE	interactor	1	0	0	FAD_binding_3 (PF01494, IPR002938): FAD binding domain SE (PF08491, IPR013698): Squalene epoxidase CBP_BcsF (PF11120, IPR019995): Cellulose biosynthesis protein BcsF
166	STK17B	interactor	3	1.000	0	Pkinase (PF00069, IPR000719): Protein kinase domain DUF2201_N (PF13203, IPR025154): Putative metallopeptidase domain
167	STOM	protein found in more fusions	7	0.533	1.785	Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family
168	STT3A	interactor	6	0.400	3.804	STT3 (PF02516, IPR003674): Oligosaccharyl transferase STT3 subunit
169	SUCLA2	interactor	4	0.500	2.500	ATP-grasp_2 (PF08442, IPR013650): ATP-grasp domain Ligase_CoA (PF00549, IPR005811): CoA-ligase nsp7 (PF08716, IPR014828): nsp7 replicase
170	SUCLG2	interactor	5	0.700	2.167	ATP-grasp_2 (PF08442, IPR013650): ATP-grasp domain Ligase_CoA (PF00549, IPR005811): CoA-ligase
171	SYVN1	protein found in more fusions	22	0.390	62.768	Alpha_GJ (PF03229, IPR004913): Alphavirus glycoprotein J zf-DHHC (PF01529, IPR001594): DHHC palmitoyltransferase zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
172	TARBP1	interactor	2	1.000	0	SpoU_methylase (PF00588, IPR001537): SpoU rRNA Methylase family
173	TBCD	interactor	2	1.000	0	HEAT (PF02985, IPR000357): HEAT repeat HEAT_PBS (PF03130, IPR004155, SM00567): PBS lyase HEAT-like repeat TFCD_C (PF12612, IPR022577): Tubulin folding cofactor D C terminal HEAT_EZ (PF13513): HEAT-like repeat
174	TCEB1	oncoprotein	6	0.667	2.650	Skp1_POZ (PF03931, IPR016073): Skp1 family, tetramerisation domain
175	TCTN2	interactor	20	0.189	116.483	DUF1619 (PF07773, IPR011677): Protein of unknown function (DUF1619)
176	TIMM17B	interactor	3	0.667	1.000	Tim17 (PF02466, IPR003397): Tim17/Tim22/Tim23/Pmp24 family
177	TIMM23	interactor	5	0.500	3.196	Tim17 (PF02466, IPR003397): Tim17/Tim22/Tim23/Pmp24 family
178	TIMM23B	interactor	2	1.000	0	Tim17 (PF02466, IPR003397): Tim17/Tim22/Tim23/Pmp24 family
179	TIMMDC1	interactor	7	0.571	7.833	Tim17 (PF02466, IPR003397): Tim17/Tim22/Tim23/Pmp24 family
180	TM9SF3	interactor	3	0.667	0.222	EMP70 (PF02990, IPR004240): Endomembrane protein 70 DUF4131 (PF13567, IPR025405): Domain of unknown function (DUF4131) DUF4231 (PF14015, IPR025325): Protein of unknown function (DUF4231)
181	TMED2	interactor	5	0.500	3.952	EMP24_GP25L (PF01105, IPR009038): emp24/gp25L/p24 family/GOLD
182	TMED9	interactor	5	0.600	2.417	EMP24_GP25L (PF01105, IPR009038): emp24/gp25L/p24 family/GOLD
183	TMEM159	interactor	2	1.000	0	IncA (PF04156, IPR007285): IncA protein Promethin (PF16015): Promethin
184	TMEM43	interactor	4	0.833	0.400	TMEM43 (PF07787, IPR012430): Transmembrane protein 43 UPF0697 (PF15117, IPR029368): Uncharacterised protein family UPF0697
185	TMEM55B	interactor	1	0	0	Tmemb_55A (PF09788, IPR019178): Transmembrane protein 55A
186	TOMM20	interactor	7	0.381	11.352	RSN1_7TM (PF02714, IPR003864): Calcium-dependent channel, 7TM region, putative phosphate MAS20 (PF02064, IPR002056): MAS20 protein import receptor
187	TOMM22	interactor	9	0.417	11.858	Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein Tom22 (PF04281, IPR005683): Mitochondrial import receptor subunit Tom22
188	TOMM40	interactor	9	0.333	17.352	Porin_3 (PF01459, IPR027246): Eukaryotic porin
189	TRA2B	interactor	7	0.571	3.486	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transformer (PF06495, IPR010519): Fruit fly transformer protein
190	TRAM1	interactor	3	0.667	0.222	TRAM1 (PF08390, IPR013599): TRAM1-like protein TRAM_LAG1_CLN8 (PF03798, IPR006634): TLC domain DUF3382 (PF11862, IPR021807): Domain of unknown function (DUF3382) DUF3671 (PF12420, IPR022139): Protein of unknown function
191	TRO	interactor	2	1.000	0	MAGE (PF01454, IPR002190): MAGE family DUF3533 (PF12051, IPR022703): Protein of unknown function (DUF3533) AP3D1 (PF06375): AP-3 complex subunit delta-1
192	TTC27	interactor	4	0.667	0.733	TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TraH (PF06122, IPR010927): Conjugative relaxosome accessory transposon protein ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 (PF13176, IPR019734): Tetratricopeptide repeat TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat TPR_14 (PF13428): Tetratricopeptide repeat TPR_16 (PF13432): Tetratricopeptide repeat
193	TUBA1A	oncoprotein	16	0.400	31.472	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
194	TUBA1B	protein found in more fusions	7	0.619	2.391	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
195	TUBA1C	protein found in more fusions	25	0.293	128.533	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
196	TUBA4A	interactor	14	0.495	16.551	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
197	TUBB3	interactor	15	0.419	30.264	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
198	TUBG1	protein found in more fusions	16	0.362	37.862	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
199	UBAC2	interactor	20	0.221	103.346	Rhomboid (PF01694, IPR022764): Rhomboid family UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
200	UBB	interactor	10	0.422	12.759	ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
201	UBC	protein found in more fusions	54	0.173	775.015	ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
202	UBE2D1	interactor	19	0.340	44.903	UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
203	UBE2J1	interactor	13	0.500	20.224	UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme ATPase-cat_bd (PF12156, IPR021993): Putative metal-binding domain of cation transport ATPase
204	UBE3A	oncoprotein	14	0.385	27.708	HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) PCM1_C (PF15717, IPR031446): Pericentriolar material 1 C terminus AZUL (PF16558, IPR032353): Amino-terminal Zinc-binding domain of ubiquitin ligase E3A
205	UBE3C	protein found in more fusions	7	0.467	2.904	IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
206	UBL4A	interactor	28	0.259	184.300	ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
207	UBQLN2	protein found in more fusions	9	0.429	7.821	Clathrin-link (PF09268, IPR015348): Clathrin, heavy-chain linker Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies) TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain XPC-binding (PF09280, IPR015360): XPC-binding domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family SUZ (PF12752, IPR024771): SUZ domain Fur_reg_FbpB (PF13040, IPR025004): Fur-regulated basic protein B
208	UBR1	interactor	7	0.762	1.669	ATPase_2 (PF01637, IPR011579): ATPase domain predominantly from Archaea ClpS (PF02617, IPR003769): ATP-dependent Clp protease adaptor protein ClpS zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box) zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
209	UBR2	interactor	4	1.000	0	ClpS (PF02617, IPR003769): ATP-dependent Clp protease adaptor protein ClpS zinc-ribbons_6 (PF07191, IPR010807): zinc-ribbons zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box) zf-ANAPC11 (PF12861, IPR024991): Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
210	UBR4	interactor	8	0.607	5.861	CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal Pheromone (PF08015, IPR012597): Fungal mating-type pheromone RecR (PF02132, IPR023628): RecR protein Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box) DZR (PF12773, IPR025874): Double zinc ribbon E3_UbLigase_R4 (PF13764, IPR025704): E3 ubiquitin-protein ligase UBR4 FAM176 (PF14851): FAM176 family
211	UBR5	protein found in more fusions	13	0.485	18.252	CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain SDA1 (PF05285, IPR007949): SDA1 HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain E3_UbLigase_EDD (PF11547, IPR024725): E3 ubiquitin ligase EDD PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein
212	UBXN1	interactor	30	0.333	139.416	Selenoprotein_S (PF06936, IPR009703): Selenoprotein S (SelS) UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain UBX (PF00789, IPR001012, SM00166): UBX domain
213	UBXN6	interactor	13	0.346	27.716	PUB (PF09409, IPR018997): PUB domain UBX (PF00789, IPR001012, SM00166): UBX domain
214	UBXN7	interactor	24	0.341	97.377	UBX (PF00789, IPR001012, SM00166): UBX domain UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif Thioredoxin_7 (PF13899): Thioredoxin-like UBA_4 (PF14555): UBA-like domain
215	UFD1L	interactor	22	0.385	76.471	UFD1 (PF03152, IPR004854): Ubiquitin fusion degradation protein UFD1
216	UNC45A	interactor	8	0.536	8.050	Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat RIX1 (PF08167, IPR012583): rRNA processing/ribosome biogenesis TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat UNC45-central (PF11701, IPR024660): Myosin-binding striated muscle assembly central TPR_16 (PF13432): Tetratricopeptide repeat HEAT_2 (PF13646): HEAT repeats
217	UQCRC2	oncoprotein	17	0.301	59.552	Peptidase_M16 (PF00675, IPR011765): Insulinase (Peptidase family M16) Peptidase_M16_C (PF05193, IPR007863): Peptidase M16 inactive domain
218	UQCRQ	interactor	10	0.311	23.852	UcrQ (PF02939, IPR004205): UcrQ family
219	USP13	interactor	11	0.618	14.555	UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein
220	USP19	interactor	13	0.244	40.869	CS (PF04969, IPR007052): CS domain UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase USP19_linker (PF16602): Linker region of USP19 deubiquitinase
221	VAPB	interactor	14	0.297	46.964	ATP-synt_G (PF04718, IPR006808): Mitochondrial ATP synthase g subunit ZapB (PF06005, IPR009252): Cell division protein ZapB Motile_Sperm (PF00635, IPR000535): MSP (Major sperm protein) domain
222	VCP	protein found in more fusions	55	0.197	730.250	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2 CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain TniB (PF05621, IPR008868): Bacterial TniB protein Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944)
223	VCPIP1	interactor	10	0.689	5.524	ATP-synt_E (PF05680, IPR008386): ATP synthase E chain OTU (PF02338, IPR003323): OTU-like cysteine protease zf-C3H1 (PF10650, IPR019607, SM00356): Putative zinc-finger domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family SDP_N (PF12278, IPR022063): Sex determination protein N terminal
224	VDAC2	interactor	17	0.287	65.754	Porin_3 (PF01459, IPR027246): Eukaryotic porin
225	VDAC3	interactor	14	0.330	36.276	Porin_3 (PF01459, IPR027246): Eukaryotic porin
226	VMP1	interactor	3	1.000	0	SNARE_assoc (PF09335, IPR015414): SNARE associated Golgi protein
227	VPS13A	interactor	3	0.667	0.500	ATG_C (PF09333, IPR015412): Autophagy-related protein C terminal domain SHR-BD (PF06650, IPR009543): SHR-binding domain of vacuolar-sorting associated protein 13 DUF1493 (PF07377, IPR010862): Protein of unknown function (DUF1493) Chorein_N (PF12624, IPR026854): N-terminal region of Chorein or VPS13 VPS13 (PF16908, IPR031646): Vacuolar sorting-associated protein 13, N-terminal VPS13_C (PF16909, IPR031645): Vacuolar-sorting-associated 13 protein C-terminal VPS13_mid_rpt (PF16910, IPR031642): Repeating coiled region of VPS13
228	VPS13C	interactor	1	0	0	ATG_C (PF09333, IPR015412): Autophagy-related protein C terminal domain SHR-BD (PF06650, IPR009543): SHR-binding domain of vacuolar-sorting associated protein 13 WWE (PF02825, IPR004170, SM00678): WWE domain Chorein_N (PF12624, IPR026854): N-terminal region of Chorein or VPS13 VPS13 (PF16908, IPR031646): Vacuolar sorting-associated protein 13, N-terminal VPS13_C (PF16909, IPR031645): Vacuolar-sorting-associated 13 protein C-terminal VPS13_mid_rpt (PF16910, IPR031642): Repeating coiled region of VPS13
229	VPS52	interactor	2	0	0	Vps52 (PF04129, IPR007258): Vps52 / Sac2 family COG5 (PF10392, IPR019465): Golgi transport complex subunit 5 Sec3_C (PF09763, IPR019160): Exocyst complex component Sec3
230	VRK2	interactor	2	1.000	0	Pkinase (PF00069, IPR000719): Protein kinase domain VP_N-CPKC (PF11475, IPR021573): Virion protein N terminal domain
231	WDR26	interactor	5	0.600	2.067	eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
232	XPR1	interactor	4	0.833	0.400	EXS (PF03124, IPR004342): EXS family SPX (PF03105, IPR004331): SPX domain
233	YES1	oncoprotein	3	0.667	0.222	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain YdjC (PF04794, IPR006879): YdjC-like protein SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
234	YIPF5	interactor	6	0.600	4.333	Yip1 (PF04893, IPR006977): Yip1 domain
235	YOD1	interactor	11	0.636	7.455	OTU (PF02338, IPR003323): OTU-like cysteine protease zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies) Ubiquitin_2 (PF14560, IPR027933): Ubiquitin-like domain
236	ZFAND2B	interactor	7	0.571	2.944	UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif zf-AN1 (PF01428, IPR000058, SM00154): AN1-like Zinc finger

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