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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins RND3, HSPA8 (from a repository: Wed Mar 8 04:22:16 2017)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)373
The number (and %) of the onco-proteins109 (29.22 %)
The number (and %) of the tumor suppressors54 (14.48 %)
Total number of binary PPIs (saturation %)4754 (6.85 %)
The number (and %) of affected PPIs371 (7.80 %)
The number of possible different fusions66
PPI diameter5
PPI radius3
The average degree of PPI24.767
Assortativity coefficient-0.1856
The network average Clustering coefficient0.452
The number (and %) of a zero Clustering coefficients19 (5.09 %)
The number (and %) of a zero Betweenness Centrality41 (10.99 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: HSPA8,RND3 All fusions
Proteins found in more fusions U2AF2 (see 2 fusions); LGALS3BP (see 2 fusions); VHL (see 1 fusions); PACSIN2 (see 1 fusions); MCL1 (see 2 fusions); CUL4A (see 4 fusions); POU2F1 (see 1 fusions); RPS4X/AHSA1 (see 1 fusions); HNRNPD (see 1 fusions); TOPBP1 (see 2 fusions); BAG3 (see 4 fusions); STUB1 (see 1 fusions); HSPB1 (see 4 fusions); SHC1 (see 1 fusions); TGM2 (see 4 fusions); ERRFI1 (see 1 fusions); HSPA8/HSPD1 (see 1 fusions); TUBG1 (see 1 fusions); MME (see 1 fusions); EEF1A1 (see 1 fusions); CBL (see 1 fusions); PPME1 (see 1 fusions); CUL3 (see 1 fusions); IVNS1ABP (see 2 fusions); GAPDH/CDKN1A (see 1 fusions); HTT (see 1 fusions); COPS5 (see 1 fusions); UBC (see 1 fusions); CCND1 (see 1 fusions); TP53 (see 3 fusions); AP2M1 (see 3 fusions); CRY2 (see 3 fusions); ATXN1 (see 3 fusions); MAPT (see 1 fusions); HSF1 (see 3 fusions); CUL1 (see 3 fusions); GRB2 (see 1 fusions); SHFM1/BAG3 (see 1 fusions); LAMP2 (see 1 fusions); TNFRSF1A (see 2 fusions); PRKDC (see 3 fusions); GAN (see 1 fusions); RPA1 (see 1 fusions); SNW1 (see 1 fusions); APP (see 4 fusions); VCP (see 4 fusions); HSP90AA1 (see 2 fusions); JAK2 (see 3 fusions); HSP90AB1 (see 1 fusions); FAF1 (see 2 fusions); ERBB3 (see 2 fusions); CDC37 (see 2 fusions); GAPDH (see 2 fusions); STAU1 (see 2 fusions); EPS15 (see 1 fusions); CDH1 (see 3 fusions); SKI (see 1 fusions); HCFC1 (see 2 fusions); LRRK2 (see 1 fusions); BCR/ABL1 (see 183 fusions); PABPC1 (see 2 fusions); BAG2 (see 1 fusions); EGFR (see 2 fusions); MCM2 (see 1 fusions); BRAF (see 3 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 HSPA8parental protein3570.06569160.581HSP70 (PF00012, IPR013126): Hsp70 protein
2 RND3parental protein140.055996.618Ras (PF00071, IPR001806, SM00173): Ras family
3 ABL1oncoprotein360.363116.901Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
F_actin_bind (PF08919, IPR015015, SM00808): F-actin binding
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
FRG2 (PF15315, IPR026245): Facioscapulohumeral muscular dystrophy candidate 2
4 AGO4interactor110.5824.756ArgoL1 (PF08699, IPR014811, SM01163): Argonaute linker 1 domain
PAZ (PF02170, IPR003100, SM00949): PAZ domain
Piwi (PF02171, IPR003165, SM00950): Piwi domain
ArgoN (PF16486, IPR032474): N-terminal domain of argonaute
ArgoMid (PF16487, IPR032473): Mid domain of argonaute
ArgoL2 (PF16488, IPR032472): Argonaute linker 2 domain
5 AHSA1protein found in more fusions270.47364.192Aha1_N (PF09229, IPR015310, SM01000): Activator of Hsp90 ATPase, N-terminal
AHSA1 (PF08327, IPR013538): Activator of Hsp90 ATPase homolog 1-like protein
6 AIPL1interactor31.0000FKBP_C (PF00254, IPR001179): FKBP-type peptidyl-prolyl cis-trans isomerase
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
7 AIREinteractor140.4747.579PHD (PF00628, IPR019787, SM00249): PHD-finger
SAND (PF01342, IPR000770, SM00258): SAND domain
HSR (PF03172, IPR004865): HSR domain; Sp100 domain
zf-PHD-like (PF15446): PHD/FYVE-zinc-finger like domain
8 AKAP5interactor21.0000WSK (PF03832, IPR001573): WSK motif
9 AKT1oncoprotein480.290540.505PH (PF00169, IPR001849, SM00233): PH domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
10 ALKBH3interactor80.5711.2222OG-FeII_Oxy_2 (PF13532, IPR027450): 2OG-Fe(II) oxygenase superfamily
11 AMBRA1interactor210.43329.693Acyl_CoA_thio (PF02551, IPR025652): Acyl-CoA thioesterase
eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Spt20 (PF12090, IPR021950): Spt20 family
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
12 AMTinteractor21.0000GCV_T (PF01571, IPR006222): Aminomethyltransferase folate-binding domain
GCV_T_C (PF08669, IPR013977): Glycine cleavage T-protein C-terminal barrel domain
13 AP2M1protein found in more fusions310.38475.478Adap_comp_sub (PF00928, IPR008968): Adaptor complexes medium subunit family
Clat_adaptor_s (PF01217, IPR022775): Clathrin adaptor complex small chain
14 APBB2interactor50.7000.828PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID)
WW (PF00397, IPR001202, SM00456): WW domain
15 APPprotein found in more fusions760.1532224.586APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding
Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP)
BUD22 (PF09073, IPR015158): BUD22
IncA (PF04156, IPR007285): IncA protein
Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus
APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
16 ARHGAP35oncoprotein40.50058.975FF (PF01846, IPR002713, SM00441): FF domain
Ras (PF00071, IPR001806, SM00173): Ras family
RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
RhoGAP-FF1 (PF16512, IPR032835): p190-A and -B Rho GAPs FF domain
17 ARHGAP5interactor206.092FF (PF01846, IPR002713, SM00441): FF domain
Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase
Ras (PF00071, IPR001806, SM00173): Ras family
RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
U5_2-snRNA_bdg (PF10597, IPR019581): U5-snRNA binding site 2 of PrP8
RhoGAP-FF1 (PF16512, IPR032835): p190-A and -B Rho GAPs FF domain
18 ARRB1interactor250.397155.540Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain
Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain
19 ARRB2interactor370.354116.854Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain
Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain
20 ASNA1interactor110.45515.528ArsA_ATPase (PF02374, IPR025723): Anion-transporting ATPase
21 ATMsuppressor220.35252.491FAT (PF02259, IPR003151): FAT domain
FATC (PF02260, IPR003152): FATC domain
HEAT (PF02985, IPR000357): HEAT repeat
PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
TAN (PF11640, IPR021668): Telomere-length maintenance and DNA damage repair
ANAPC5 (PF12862, IPR026000): Anaphase-promoting complex subunit 5
22 ATP13A2interactor30.6670.667E1-E2_ATPase (PF00122, IPR008250): E1-E2 ATPase
Hydrolase (PF00702, IPR023214): haloacid dehalogenase-like hydrolase
MARVEL (PF01284, IPR008253): Membrane-associating domain
P5-ATPase (PF12409, IPR006544): P5-type ATPase cation transporter
23 ATXN1protein found in more fusions140.38520.042AXH (PF08517, IPR013723, SM00536): Ataxin-1 and HBP1 module (AXH)
Spt20 (PF12090, IPR021950): Spt20 family
ATXN-1_C (PF12547, IPR020997): Capicua transcriptional repressor modulator
Cnd1_N (PF12922, IPR024324): non-SMC mitotic condensation complex subunit 1, N-term
24 ATXN10interactor70.8100.284RIH_assoc (PF08454, IPR013662): RyR and IP3R Homology associated
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
25 AURKAoncoprotein390.344161.475Pkinase (PF00069, IPR000719): Protein kinase domain
MTBP_C (PF14920, IPR029418): MDM2-binding
26 BAG1oncoprotein220.30366.567BAG (PF02179, IPR003103, SM00264): BAG domain
Presenilin (PF01080, IPR001108): Presenilin
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082)
27 BAG2protein found in more fusions420.300180.474IncA (PF04156, IPR007285): IncA protein
Mnd1 (PF03962, IPR005647): Mnd1 family
ParD_antitoxin (PF03693, IPR022789): Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH
28 BAG3oncoprotein380.227213.417BAG (PF02179, IPR003103, SM00264): BAG domain
WW (PF00397, IPR001202, SM00456): WW domain
29 BAG4interactor230.39158.286BAG (PF02179, IPR003103, SM00264): BAG domain
DMP12 (PF16779, IPR031891): DNA-mimic protein
30 BCAS2interactor210.31994.500BCAS2 (PF05700, IPR008409): Breast carcinoma amplified sequence 2 (BCAS2)
ZapB (PF06005, IPR009252): Cell division protein ZapB
31 BCRsuppressor180.57512.334Bcr-Abl_Oligo (PF09036, IPR015123): Bcr-Abl oncoprotein oligomerisation domain
C2 (PF00168, IPR000008, SM00239): C2 domain
PH (PF00169, IPR001849, SM00233): PH domain
RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
IQ_SEC7_PH (PF16453, IPR001849): PH domain
32 BRAFoncoprotein160.52434.972Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
RBD (PF02196, IPR003116, SM00455): Raf-like Ras-binding domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
33 BRCA1suppressor470.228327.976BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT
34 C12orf10interactor80.6791.492UPF0160 (PF03690, IPR003226): Uncharacterised protein family (UPF0160)
35 C17orf49interactor60.3332.534Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
36 C1QBPinteractor300.47439.783MAM33 (PF02330, IPR003428): Mitochondrial glycoprotein
DUF3053 (PF11254, IPR021413): Protein of unknown function (DUF3053)
37 CADoncoprotein320.30487.483Amidohydro_1 (PF01979, IPR006680): Amidohydrolase family
CPSase_L_D2 (PF02786, IPR005479): Carbamoyl-phosphate synthase L chain, ATP binding domain
CPSase_L_D3 (PF02787, IPR005480, SM01096): Carbamoyl-phosphate synthetase large chain, oligomerisation domain
CPSase_sm_chain (PF00988, IPR002474, SM01097): Carbamoyl-phosphate synthase small chain, CPSase domain
GATase (PF00117, IPR017926): Glutamine amidotransferase class-I
MGS (PF02142, IPR011607, SM00851): MGS-like domain
OTCace (PF00185, IPR006131): Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain
OTCace_N (PF02729, IPR006132): Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain
ATPgrasp_Ter (PF15632, IPR011226): ATP-grasp in the biosynthetic pathway with Ter operon
38 CAMKMTinteractor60.7330.761Methyltransf_16 (PF10294, IPR019410): Lysine methyltransferase
39 CAND1interactor650.363454.913Adaptin_N (PF01602, IPR002553): Adaptin N terminal region
DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981)
HEAT (PF02985, IPR000357): HEAT repeat
TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20)
RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1
DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385)
MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II
40 CAPZA1interactor260.26262.310F-actin_cap_A (PF01267, IPR002189): F-actin capping protein alpha subunit
41 CAPZBinteractor210.31928.540Cytochrom_B562 (PF07361, IPR009155): Cytochrome b562
F_actin_cap_B (PF01115, IPR001698): F-actin capping protein, beta subunit
42 CBLsuppressor370.333210.449Cbl_N (PF02262, IPR003153): CBL proto-oncogene N-terminal domain 1
Cbl_N2 (PF02761, IPR014741): CBL proto-oncogene N-terminus, EF hand-like domain
Cbl_N3 (PF02762, IPR014742): CBL proto-oncogene N-terminus, SH2-like domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain
43 CCAR2suppressor230.36444.098DREPP (PF05558, IPR008469): DREPP plasma membrane polypeptide
IncA (PF04156, IPR007285): IncA protein
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
DBC1 (PF14443, IPR025954, SM01122): DBC1
S1-like (PF14444, IPR025223): S1-like
44 CCDC117interactor51.0000CCDC117 (PF15810, IPR031630): Coiled-coil domain-containing protein 117
45 CCND1oncoprotein180.47819.009Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain
Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
46 CCNI2interactor21.0000Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
47 CD4suppressor190.33347.197ATP1G1_PLM_MAT8 (PF02038, IPR000272): ATP1G1/PLM/MAT8 family
C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain
CD4-extracel (PF09191, IPR015274): CD4, extracellular
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
Tcell_CD4_C (PF12104, IPR021963): T cell CD4 receptor C terminal region
48 CDC20oncoprotein220.48630.517WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
49 CDC37protein found in more fusions390.336196.925CDC37_C (PF08564, IPR013873, SM01069): Cdc37 C terminal domain
CDC37_M (PF08565, IPR013874, SM01070): Cdc37 Hsp90 binding domain
CDC37_N (PF03234, IPR013855, SM01071): Cdc37 N terminal kinase binding
Rho_Binding (PF08912, IPR015008): Rho Binding
TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
50 CDC5Linteractor610.284407.849OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat
Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component
Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain
51 CDCA5interactor31.0000Sororin (PF09666, IPR018605): Sororin protein
52 CDH1suppressor160.34325.360Cadherin_C (PF01049, IPR000233): Cadherin cytoplasmic region
Cadherin_pro (PF08758, IPR014868, SM01055): Cadherin prodomain like
Cadherin (PF00028, IPR002126, SM00112): Cadherin domain
53 CDK11Boncoprotein130.40913.015DDHD (PF02862, IPR004177, SM01127): DDHD domain
DivIC (PF04977, IPR007060): Septum formation initiator
Pkinase (PF00069, IPR000719): Protein kinase domain
DUF4748 (PF15932, IPR031833): Domain of unknown function (DUF4748)
54 CDK2suppressor670.274586.580Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family
Pkinase (PF00069, IPR000719): Protein kinase domain
55 CDK4oncoprotein250.41737.625Pkinase (PF00069, IPR000719): Protein kinase domain
56 CDK5RAP3interactor80.5713.141DUF773 (PF05600, IPR008491): Protein of unknown function (DUF773)
57 CDKN1Asuppressor360.371119.202CDI (PF02234, IPR003175): Cyclin-dependent kinase inhibitor
58 CDKN1Bsuppressor240.37365.114CDI (PF02234, IPR003175): Cyclin-dependent kinase inhibitor
Multi-haem_cyto (PF13447): Seven times multi-haem cytochrome CxxCH
59 CDKN2Asuppressor310.37297.278Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
60 CENPAinteractor80.5243.000Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
61 CEP250interactor270.38542.201ACCA (PF03255, IPR001095): Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
DASH_Dam1 (PF08653, IPR013962): DASH complex subunit Dam1
DivIC (PF04977, IPR007060): Septum formation initiator
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
EHN (PF06441, IPR010497): Epoxide hydrolase N terminus
ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
IncA (PF04156, IPR007285): IncA protein
Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain
SlyX (PF04102, IPR007236): SlyX
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
Syntaxin-6_N (PF09177, IPR015260): Syntaxin 6, N-terminal
TSC22 (PF01166, IPR000580): TSC-22/dip/bun family
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
Endonuc_Holl (PF10107, IPR019287): Endonuclease related to archaeal Holliday junction resolvase
DUF2570 (PF10828, IPR022538): Protein of unknown function (DUF2570)
DGF-1_C (PF11040, IPR021053): Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus
DUF2968 (PF11180, IPR021350): Protein of unknown function (DUF2968)
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915)
DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404)
DUF4472 (PF14739, IPR029329): Domain of unknown function (DUF4472)
Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion
KAsynt_C_assoc (PF16197, IPR032821): Ketoacyl-synthetase C-terminal extension
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
62 CFTRsuppressor300.33561.749ABC_membrane (PF00664, IPR001140): ABC transporter transmembrane region
ABC_tran (PF00005, IPR003439): ABC transporter
Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase
SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
Rotamase_2 (PF13145, IPR000297): PPIC-type PPIASE domain
CFTR_R (PF14396, IPR025837): Cystic fibrosis TM conductance regulator (CFTR), regulator domain
63 CITinteractor207.405ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
CNH (PF00780, IPR001180, SM00036): CNH domain
Dec-1 (PF04624, IPR006718): Dec-1 repeat
DivIC (PF04977, IPR007060): Septum formation initiator
DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948)
Fez1 (PF06818): Fez1
PH (PF00169, IPR001849, SM00233): PH domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
SlyX (PF04102, IPR007236): SlyX
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
DUF2570 (PF10828, IPR022538): Protein of unknown function (DUF2570)
KfrA_N (PF11740, IPR021104): Plasmid replication region DNA-binding N-term
Alanine_zipper (PF11839, IPR021793): Alanine-zipper, major outer membrane lipoprotein
Noelin-1 (PF12308, IPR022082): Neurogenesis glycoprotein
TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
64 CITED1interactor31.0000CITED (PF04487, IPR007576): CITED
65 CLTAinteractor170.35321.789Clathrin_lg_ch (PF01086, IPR000996): Clathrin light chain
66 COPS5protein found in more fusions760.327512.360JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
67 COPS6interactor420.452161.826DUF320 (PF03777, IPR005528): Small secreted domain (DUF320)
JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function
68 CPS1interactor110.5453.358CPSase_L_D2 (PF02786, IPR005479): Carbamoyl-phosphate synthase L chain, ATP binding domain
CPSase_L_D3 (PF02787, IPR005480, SM01096): Carbamoyl-phosphate synthetase large chain, oligomerisation domain
CPSase_sm_chain (PF00988, IPR002474, SM01097): Carbamoyl-phosphate synthase small chain, CPSase domain
GATase (PF00117, IPR017926): Glutamine amidotransferase class-I
MerR-DNA-bind (PF09278, IPR015358): MerR, DNA binding
MGS (PF02142, IPR011607, SM00851): MGS-like domain
69 CRKoncoprotein320.39995.743SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_2 (PF07653, IPR011511): Variant SH3 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
70 CRY2protein found in more fusions240.34861.747DNA_photolyase (PF00875, IPR006050): DNA photolyase
FAD_binding_7 (PF03441, IPR005101): FAD binding domain of DNA photolyase
71 CTNNB1oncoprotein420.235347.829Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361)
HEAT_EZ (PF13513): HEAT-like repeat
72 CUL1suppressor820.300951.743Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
73 CUL2suppressor510.405204.438Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
74 CUL3protein found in more fusions1040.2321416.979Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
75 CUL4Aprotein found in more fusions480.397211.559Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
76 CUL4Boncoprotein480.458127.141Cullin (PF00888, IPR001373, SM00182): Cullin family
EBP50_C (PF09007, IPR015098): EBP50, C-terminal
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
PG_binding_4 (PF12229, IPR022029): Putative peptidoglycan binding domain
MDFI (PF15316, IPR026134): MyoD family inhibitor
77 CUL5suppressor490.476134.911Cullin (PF00888, IPR001373, SM00182): Cullin family
GlutR_dimer (PF00745, IPR015896): Glutamyl-tRNAGlu reductase, dimerisation domain
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
78 CWC15interactor70.6673.594Cwf_Cwc_15 (PF04889, IPR006973): Cwf15/Cwc15 cell cycle control protein
79 CYCSinteractor40.6670.165Cytochrom_C (PF00034, IPR003088): Cytochrome c
80 CYP3A4interactor31.0000p450 (PF00067, IPR001128): Cytochrome P450
81 DCUN1D1interactor350.59735.165Cullin_binding (PF03556, IPR005176): Cullin binding
UBA_4 (PF14555): UBA-like domain
82 DENND2Dsuppressor50.7001.486dDENN (PF03455, IPR005112, SM00801): dDENN domain
DENN (PF02141, IPR001194, SM00799): DENN (AEX-3) domain
uDENN (PF03456, IPR005113, SM00800): uDENN domain
83 DGCR8interactor70.5242.615dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
WW (PF00397, IPR001202, SM00456): WW domain
84 DNAJA1interactor590.240490.368DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
85 DNAJA2interactor340.37499.673DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
86 DNAJA3suppressor200.38935.748DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
87 DNAJA4interactor170.44116.567DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
88 DNAJB1suppressor410.293192.203DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
89 DNAJB11interactor170.50022.570DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
90 DNAJB12interactor70.4764.303DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DUF1977 (PF09320, IPR015399): Domain of unknown function (DUF1977)
TPR_19 (PF14559): Tetratricopeptide repeat
91 DNAJB14interactor41.0000DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DUF1977 (PF09320, IPR015399): Domain of unknown function (DUF1977)
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
92 DNAJB2interactor70.4294.584DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
93 DNAJB4suppressor170.47117.732DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
94 DNAJB6interactor190.40428.953DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
95 DNAJC1interactor30.6670.027DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
DUF4234 (PF14018, IPR025328): Domain of unknown function (DUF4234)
96 DNAJC13interactor60.6671.141Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
Arm_2 (PF04826, IPR006911): Armadillo-like
DUF4339 (PF14237, IPR025640): Domain of unknown function (DUF4339)
97 DNAJC2interactor50.9000.250DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
Mnd1 (PF03962, IPR005647): Mnd1 family
Rotamase (PF00639, IPR000297): PPIC-type PPIASE domain
S1FA (PF04689, IPR006779): DNA binding protein S1FA
DUF2058 (PF09831, IPR018636): Uncharacterized protein conserved in bacteria (DUF2058)
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
GHBP (PF12772, IPR025871): Growth hormone receptor binding
RAC_head (PF16717, IPR032003): Ribosome-associated complex head domain
98 DNAJC3interactor70.7141.052DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_21 (PF09976, IPR018704): Tetratricopeptide repeat-like domain
Ndufs5 (PF10200, IPR019342): NADH:ubiquinone oxidoreductase, NDUFS5-15kDa
TPR_8 (PF13181, IPR019734): Tetratricopeptide repeat
TPR_16 (PF13432): Tetratricopeptide repeat
DUF4363 (PF14276, IPR025373): Domain of unknown function (DUF4363)
TPR_19 (PF14559): Tetratricopeptide repeat
99 DNAJC7interactor330.379100.438DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
Rapsyn_N (PF10579, IPR019568): Rapsyn N-terminal myristoylation and linker region
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_17 (PF13431): Tetratricopeptide repeat
100 DNAJC9oncoprotein150.59011.298DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
101 DRG2interactor100MMR_HSR1 (PF01926, IPR006073): 50S ribosome-binding GTPase
TGS (PF02824, IPR004095): TGS domain
MMR_HSR1_Xtn (PF16897, IPR031662): C-terminal region of MMR_HSR1 domain
102 DUTinteractor150.53312.238dUTPase (PF00692, IPR008180): dUTPase
103 DYRK2interactor110.4915.212Pkinase (PF00069, IPR000719): Protein kinase domain
104 EBNA1BP2interactor130.50016.609Ebp2 (PF05890, IPR008610): Eukaryotic rRNA processing protein EBP2
105 EDRF1oncoprotein40.6670.582TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
DUF2315 (PF10231, IPR018796): Uncharacterised conserved protein (DUF2315)
106 EEDsuppressor370.292129.654WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
107 EEF1A1suppressor930.2421087.405GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain
108 EEF2interactor520.376206.261EFG_C (PF00679, IPR000640, SM00838): Elongation factor G C-terminus
EFG_IV (PF03764, IPR005517, SM00889): Elongation factor G, domain IV
GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
EFG_II (PF14492, IPR009022): Elongation Factor G, domain II
109 EGFRoncoprotein870.2201227.093Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT)
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
110 EIF4A3interactor380.363165.146DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
111 EPS15oncoprotein210.47933.268Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391)
EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
112 ERBB3oncoprotein250.41345.275Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
113 ERGoncoprotein160.44214.593Ets (PF00178, IPR000418, SM00413): Ets-domain
SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain
114 ERHinteractor120.27336.766ER (PF01133, IPR000781): Enhancer of rudimentary
115 ERRFI1suppressor160.45723.367GTPase_binding (PF09027, IPR015116): GTPase binding
Inhibitor_Mig-6 (PF11555, IPR021619): EGFR receptor inhibitor Mig-6
116 ESR1suppressor800.2131018.053Oest_recep (PF02159, IPR001292): Oestrogen receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal
117 ESR2suppressor130.5307.382zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
ERbeta_N (PF12497, IPR021064): Estrogen receptor beta
118 ESRRBsuppressor230.47033.781zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
119 ETFBKMTinteractor31.0000PrmA (PF06325, IPR010456): Ribosomal protein L11 methyltransferase (PrmA)
120 FAF1protein found in more fusions230.37253.408UBX (PF00789, IPR001012, SM00166): UBX domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
AAA_11 (PF13086): AAA domain
UBA_4 (PF14555): UBA-like domain
121 FAM189Binteractor21.0000CD20 (PF04103, IPR007237): CD20-like family
TMEM252 (PF15664, IPR031363): Transmembrane protein 252 family
122 FANCConcoprotein70.4762.123Fanconi_C (PF02106, IPR000686): Fanconi anaemia group C protein
123 FBP1suppressor40.6670.111FBPase (PF00316, IPR000146): Fructose-1-6-bisphosphatase, N-terminal domain
124 FBXO25suppressor190.37430.591Elongin_A (PF06881, IPR010684): RNA polymerase II transcription factor SIII (Elongin) subunit A
125 FBXO6interactor510.293218.382FBA (PF04300, IPR007397): F-box associated region
F-box-like (PF12937, IPR001810): F-box-like
126 FBXW7suppressor230.169355.773Mem_trans (PF03547, IPR004776): Membrane transport protein
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
F-box-like (PF12937, IPR001810): F-box-like
127 FDPSinteractor90.4727.388polyprenyl_synt (PF00348, IPR000092): Polyprenyl synthetase
128 FGFR3oncoprotein80.6191.202I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Ig_3 (PF13927): Immunoglobulin domain
Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
129 FLYWCH2interactor21.0000FLYWCH_N (PF15423, IPR029279): FLYWCH-type zinc finger-containing protein
130 FN1oncoprotein680.251490.598fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain
fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
131 FUSsuppressor590.402237.536Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
Limkain-b1 (PF11608, IPR024582): Limkain b1
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
Keratin_2_head (PF16208, IPR032444): Keratin type II head
132 GABRB1interactor21.0000Neur_chan_LBD (PF02931, IPR006202): Neurotransmitter-gated ion-channel ligand binding domain
Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
133 GANprotein found in more fusions230.34664.217BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
Kelch_3 (PF13415): Galactose oxidase, central domain
Kelch_5 (PF13854): Kelch motif
134 GAPDHoncoprotein670.310430.196Gp_dh_C (PF02800, IPR020829): Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
Gp_dh_N (PF00044, IPR020828, SM00846): Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
OstA (PF03968, IPR005653): OstA-like protein
135 GCH1interactor50.6670.800GTP_cyclohydroI (PF01227, IPR020602): GTP cyclohydrolase I
136 GOT2oncoprotein60.8000.235Aminotran_1_2 (PF00155, IPR004839): Aminotransferase class I and II
137 GPN1interactor120.43912.618ATP_bind_1 (PF03029, IPR004130): Conserved hypothetical ATP binding protein
NB-ARC (PF00931, IPR002182): NB-ARC domain
138 GPR37interactor70.8570.2317tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
139 GRB2oncoprotein560.300763.857SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
DUF5093 (PF17011, IPR031533): Domain of unknown function (DUF5093)
140 GRPEL1interactor200.42139.050GrpE (PF01025, IPR000740): GrpE
141 HAUS1interactor140.42315.239THP2 (PF09432, IPR018557): Tho complex subunit THP2
XhlA (PF10779, IPR019715): Haemolysin XhlA
DUF3496 (PF12001, IPR021885): Domain of unknown function (DUF3496)
142 HAUS2interactor100.4443.925DpnII (PF04556, IPR007637): DpnII restriction endonuclease
HAUS2 (PF15003, IPR028346): HAUS augmin-like complex subunit 2
143 HCFC1protein found in more fusions180.40449.517fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
Kelch_3 (PF13415): Galactose oxidase, central domain
Kelch_5 (PF13854): Kelch motif
zf-tcix (PF14952, IPR029269): Putative treble-clef, zinc-finger, Zn-binding
144 HDAC10interactor60.4672.758Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
145 HDAC3suppressor170.39236.554Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
146 HDAC6oncoprotein380.314173.319Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
PSGP (PF07276, IPR009900): Apopolysialoglycoprotein (PSGP)
zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein
147 HEMGNinteractor30.6670.500BRF1 (PF07741, IPR011665): Brf1-like TBP-binding domain
148 HERC5interactor90.4294.605Peptidase_S51 (PF03575, IPR005320): Peptidase family S51
RCC1 (PF00415, IPR000408): Regulator of chromosome condensation (RCC1) repeat
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
RCC1_2 (PF13540): Regulator of chromosome condensation (RCC1) repeat
149 HGSinteractor190.275843.148FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
VHS (PF00790, IPR002014, SM00288): VHS domain
EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region
Hrs_helical (PF12210, IPR024641): Hepatocyte growth factor-regulated tyrosine kinase substrate
PIEZO (PF15917, IPR031805): Piezo
150 HIF1Asuppressor310.351116.831Dicty_REP (PF05086, IPR007778): Dictyostelium (Slime Mold) REP protein
HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
PAS (PF00989, IPR013767, SM00091): PAS fold
PAS_3 (PF08447, IPR013655): PAS fold
HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1
151 HIST3H3interactor180.28852.337Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
152 HLA-DRAinteractor60.9330.043MHC_II_alpha (PF00993, IPR001003, SM00920): Class II histocompatibility antigen, alpha domain
C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
C1-set_C (PF16196, IPR032431): C1-set C-terminal domain
153 HLA-DRB1interactor90.7863.243DUF202 (PF02656, IPR003807): Domain of unknown function (DUF202)
MHC_II_beta (PF00969, IPR000353, SM00921): Class II histocompatibility antigen, beta domain
C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
154 HLA-DRB3interactor50.9000.043DUF202 (PF02656, IPR003807): Domain of unknown function (DUF202)
MHC_II_beta (PF00969, IPR000353, SM00921): Class II histocompatibility antigen, beta domain
C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
155 HLA-DRB4interactor40.8330.043DUF202 (PF02656, IPR003807): Domain of unknown function (DUF202)
MHC_II_beta (PF00969, IPR000353, SM00921): Class II histocompatibility antigen, beta domain
C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
156 HLA-DRB5interactor60.9330.043MHC_II_beta (PF00969, IPR000353, SM00921): Class II histocompatibility antigen, beta domain
C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
157 HLTFsuppressor150.37453.227HIRAN (PF08797, IPR014905, SM00910): HIRAN domain
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
158 HMGB1oncoprotein100.4005.481HMG_box_2 (PF09011, IPR009071): HMG-box domain
NOA36 (PF06524, IPR010531): NOA36 protein
HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
159 HNRNPA1interactor820.312815.406RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1
160 HNRNPA3oncoprotein420.423100.538IATP (PF04568, IPR007648): Mitochondrial ATPase inhibitor, IATP
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
161 HNRNPDoncoprotein560.331515.619CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain
NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Keratin_2_head (PF16208, IPR032444): Keratin type II head
162 HSF1protein found in more fusions180.39042.677DUF247 (PF03140, IPR004158): Plant protein of unknown function
Vert_HS_TF (PF06546, IPR010542): Vertebrate heat shock transcription factor
HSF_DNA-bind (PF00447, IPR000232, SM00415): HSF-type DNA-binding
163 HSP90AA1oncoprotein1520.1594843.194HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
164 HSP90AB1oncoprotein1150.2001910.026HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
165 HSPA1Ainteractor1180.1512841.346HSP70 (PF00012, IPR013126): Hsp70 protein
166 HSPA2interactor440.226352.848HSP70 (PF00012, IPR013126): Hsp70 protein
167 HSPA4interactor990.1652029.535Herpes_ICP4_N (PF03584, IPR005206): Herpesvirus ICP4-like protein N-terminal region
HSP70 (PF00012, IPR013126): Hsp70 protein
TP53IP5 (PF15331, IPR029290): Cellular tumour antigen p53-inducible 5
168 HSPA4Linteractor190.33948.538HSP70 (PF00012, IPR013126): Hsp70 protein
169 HSPA5oncoprotein1310.1693192.420HSP70 (PF00012, IPR013126): Hsp70 protein
170 HSPA6interactor500.176553.190HSP70 (PF00012, IPR013126): Hsp70 protein
171 HSPA9oncoprotein1020.1621852.521HSP70 (PF00012, IPR013126): Hsp70 protein
172 HSPB1oncoprotein600.271658.626HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family
173 HSPBP1interactor150.39032.467Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
Fes1 (PF08609, IPR013918): Nucleotide exchange factor Fes1
Rcd1 (PF04078, IPR007216): Cell differentiation family, Rcd1-like
HEAT_EZ (PF13513): HEAT-like repeat
174 HSPD1suppressor760.234820.486Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
175 HSPH1oncoprotein260.46845.290HSP70 (PF00012, IPR013126): Hsp70 protein
SICA_alpha (PF12887, IPR024290): SICA extracellular alpha domain
176 HTN3interactor100AJAP1_PANP_C (PF15298, IPR029198): AJAP1/PANP C-terminus
177 HTTprotein found in more fusions160.43820.481HEAT (PF02985, IPR000357): HEAT repeat
SPX (PF03105, IPR004331): SPX domain
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
DUF3652 (PF12372, IPR024613): Huntingtin protein region
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
178 HYOU1interactor160.41722.179HSP70 (PF00012, IPR013126): Hsp70 protein
AbiEi_3_N (PF17194): Transcriptional regulator, AbiEi antitoxin N-terminal domain
179 ID2oncoprotein90.5001.902HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
180 IL16oncoprotein50.5003.000PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
SUZ (PF12752, IPR024771): SUZ domain
181 IL32interactor200IL32 (PF15225, IPR028067): Interleukin 32
182 INPPL1oncoprotein230.52630.540Exo_endo_phos (PF03372, IPR005135): Endonuclease/Exonuclease/phosphatase family
SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
SH2 (PF00017, IPR000980, SM00252): SH2 domain
183 INSIG2interactor60.8000.650INSIG (PF07281, IPR025929): Insulin-induced protein (INSIG)
184 IPO7interactor200.37939.134Cse1 (PF08506, IPR013713): Cse1
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
RIX1 (PF08167, IPR012583): rRNA processing/ribosome biogenesis
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457)
DUF3730 (PF12530, IPR022542): Protein of unknown function (DUF3730)
185 IQCB1interactor180.43826.385DUF1765 (PF08578, IPR013887): Protein of unknown function (DUF1765)
IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
HJURP_C (PF12347, IPR022102): Holliday junction regulator protein family C-terminal repeat
Condensin2nSMC (PF12422, IPR024741): Condensin II non structural maintenance of chromosomes subunit
186 IRAK1interactor230.35561.376Death (PF00531, IPR000488, SM00005): Death domain
Pkinase (PF00069, IPR000719): Protein kinase domain
187 ISG15suppressor210.36751.494ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
188 ITGA4interactor560.258316.855FG-GAP (PF01839, IPR013517): FG-GAP repeat
Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region
Integrin_alpha2 (PF08441, IPR013649): Integrin alpha
189 IVNS1ABPprotein found in more fusions110.5783.641BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
190 JAK2oncoprotein170.40035.069FERM_M (PF00373, IPR019748): FERM central domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
191 JUNoncoprotein220.37160.216bZIP_1 (PF00170, IPR004827): bZIP transcription factor
Jun (PF03957, IPR005643): Jun-like transcription factor
192 KCNA5interactor41.0000Ion_trans (PF00520, IPR005821): Ion transport protein
BTB_2 (PF02214, IPR003131): BTB/POZ domain
193 KCND3interactor30.6670.083Ion_trans (PF00520, IPR005821): Ion transport protein
BTB_2 (PF02214, IPR003131): BTB/POZ domain
Shal-type (PF11601, IPR021645): Shal-type voltage-gated potassium channels, N-terminal
DUF3399 (PF11879, IPR024587): Domain of unknown function (DUF3399)
194 KCNH2interactor110.6007.959Ion_trans (PF00520, IPR005821): Ion transport protein
cNMP_binding (PF00027, IPR000595, SM00100): Cyclic nucleotide-binding domain
PAS_9 (PF13426, IPR000014): PAS domain
195 KCNJ10interactor40.5002.144IRK (PF01007, IPR016449): Inward rectifier potassium channel
196 KCNQ4interactor50.7000.295Ion_trans (PF00520, IPR005821): Ion transport protein
KCNQ_channel (PF03520, IPR013821): KCNQ voltage-gated potassium channel
197 KIAA1107interactor100Acyl-thio_N (PF12590, IPR021113): Acyl-ATP thioesterase
SOBP (PF15279, IPR026092): Sine oculis-binding protein
DUF4596 (PF15363, IPR027907): Domain of unknown function (DUF4596)
198 KIAA1191interactor40.6670.619P33MONOX (PF15302, IPR026759): P33 mono-oxygenase
199 KIF1Cinteractor40.8330.133FHA (PF00498, IPR000253, SM00240): FHA domain
IncA (PF04156, IPR007285): IncA protein
Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
Kinesin_assoc (PF16183, IPR032405): Kinesin-associated
200 KNSTRNinteractor50.8000.198FlpD (PF02662, IPR003813): Methyl-viologen-reducing hydrogenase, delta subunit
KxDL (PF10241, IPR019371): Uncharacterized conserved protein
Matrilin_ccoil (PF10393, IPR019466): Trimeric coiled-coil oligomerisation domain of matrilin
201 LALBAinteractor100Lys (PF00062, IPR001916, SM00263): C-type lysozyme/alpha-lactalbumin family
202 LAMP2protein found in more fusions100.3897.230Lamp (PF01299, IPR002000): Lysosome-associated membrane glycoprotein (Lamp)
203 LGALS3BPoncoprotein340.52153.470BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
SRCR (PF00530, IPR001190): Scavenger receptor cysteine-rich domain
SRCR_2 (PF15494, IPR017448): Scavenger receptor cysteine-rich domain
204 LMAN1interactor80.6432.137Lectin_leg-like (PF03388, IPR005052): Legume-like lectin family
Golgin_A5 (PF09787, IPR019177): Golgin subfamily A member 5
KxDL (PF10241, IPR019371): Uncharacterized conserved protein
DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404)
205 LMNB1interactor180.36628.635Filament (PF00038, IPR001664): Intermediate filament protein
LTD (PF00932, IPR001322): Lamin Tail Domain
206 LPGAT1interactor100Acyltransferase (PF01553, IPR002123, SM00563): Acyltransferase
Acyltransf_C (PF16076, IPR032098): Acyltransferase C-terminus
207 LRPPRCinteractor300.189106.556DED (PF01335, IPR001875, SM00031): Death effector domain
MA3 (PF02847, IPR003891, SM00544): MA3 domain
PPR (PF01535, IPR002885): PPR repeat
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
ApoB100_C (PF12491, IPR022176): Apolipoprotein B100 C terminal
PPR_2 (PF13041, IPR002885): PPR repeat family
PPR_3 (PF13812, IPR002885): Pentatricopeptide repeat domain
TPR_19 (PF14559): Tetratricopeptide repeat
PPR_long (PF17177): Pentacotripeptide-repeat region of PROPR
208 LRRC28interactor30.6670.118LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
209 LRRK2oncoprotein230.44622.752Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain
DUF1043 (PF06295, IPR009386): Protein of unknown function (DUF1043)
T2SSE (PF00437, IPR001482): Type II/IV secretion system protein
Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase
Pkinase (PF00069, IPR000719): Protein kinase domain
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
PQQ_2 (PF13360, IPR002372): PQQ-like domain
LRR_8 (PF13855, IPR001611): Leucine rich repeat
COR (PF16095, IPR032171): C-terminal of Roc, COR, domain
210 MAGOHinteractor200.34238.315Mago_nashi (PF02792, IPR004023): Mago nashi protein
211 MAML1interactor31.0000MamL-1 (PF09596, IPR019082): MamL-1 domain
Kri1 (PF05178, IPR018034): KRI1-like family
PRIMA1 (PF16101): Proline-rich membrane anchor 1
212 MAP2K1oncoprotein100.5834.468Pkinase (PF00069, IPR000719): Protein kinase domain
DUF3216 (PF11505, IPR023108): Protein of unknown function (DUF3216)
213 MAPK8oncoprotein220.27665.794DUF530 (PF04409, IPR007503): Protein of unknown function (DUF530)
Pkinase (PF00069, IPR000719): Protein kinase domain
214 MAPTprotein found in more fusions220.42930.340Tubulin-binding (PF00418, IPR001084): Tau and MAP protein, tubulin-binding repeat
215 MCF2oncoprotein41.0000PH (PF00169, IPR001849, SM00233): PH domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
Spectrin (PF00435, IPR002017): Spectrin repeat
CRAL_TRIO_2 (PF13716, IPR001251): Divergent CRAL/TRIO domain
SPG48 (PF14764, IPR028222): AP-5 complex subunit, vesicle trafficking
216 MCL1oncoprotein90.50012.808Bcl-2 (PF00452, IPR026298): Apoptosis regulator proteins, Bcl-2 family
217 MCM2oncoprotein850.256848.099AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA)
MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
218 MCM5oncoprotein310.428110.813MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
219 MDM2oncoprotein580.235576.108Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region
Presenilin (PF01080, IPR001108): Presenilin
SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain
zf-FPG_IleRS (PF06827, IPR010663): Zinc finger found in FPG and IleRS
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
220 MEN1suppressor120.4249.213Menin (PF05053, IPR007747): Menin
221 METTL21Aoncoprotein110.5279.175Methyltransf_16 (PF10294, IPR019410): Lysine methyltransferase
222 METTL21Binteractor150.45715.693Methyltransf_16 (PF10294, IPR019410): Lysine methyltransferase
223 METTL21Cinteractor50.8001.067Methyltransf_16 (PF10294, IPR019410): Lysine methyltransferase
224 METTL22interactor50.7000.277Methyltransf_16 (PF10294, IPR019410): Lysine methyltransferase
225 MKKSinteractor51.0000Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
226 MMEsuppressor100.4179.576Peptidase_M13 (PF01431, IPR018497): Peptidase family M13
Peptidase_M13_N (PF05649, IPR008753): Peptidase family M13
227 MST1Rsuppressor110.50910.216Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
PSI (PF01437, IPR002165, SM00423): Plexin repeat
Sema (PF01403, IPR001627, SM00630): Sema domain
TIG (PF01833, IPR002909): IPT/TIG domain
228 NACAoncoprotein120.4856.105NAC (PF01849, IPR002715): NAC domain
RNA_pol_Rpo13 (PF12136, IPR021985): RNA polymerase Rpo13 subunit HTH domain
CitT (PF12431, IPR028141): Transcriptional regulator
229 NANOGinteractor140.34614.096Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
230 NAPRTinteractor50.4002.190NAPRTase (PF04095, IPR007229): Nicotinate phosphoribosyltransferase (NAPRTase) family
231 NAXEinteractor100YjeF_N (PF03853, IPR004443): YjeF-related protein N-terminus
232 NDRG2suppressor100Ndr (PF03096, IPR004142): Ndr family
233 NECAP2interactor60.5335.120DUF1681 (PF07933, IPR012466): Protein of unknown function (DUF1681)
234 NEDD8interactor460.463107.699ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
235 NLRP12interactor50.8000.467NACHT (PF05729): NACHT domain
PYRIN (PF02758, IPR004020): PAAD/DAPIN/Pyrin domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
LRR_8 (PF13855, IPR001611): Leucine rich repeat
FISNA (PF14484, IPR029495): Fish-specific NACHT associated domain
236 NMIinteractor60.5005.167IFP_35_N (PF07334, IPR009938): Interferon-induced 35 kDa protein (IFP 35) N-terminus
NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID)
237 NOA1interactor100DUF258 (PF03193, IPR004881): Protein of unknown function, DUF258
GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
MMR_HSR1 (PF01926, IPR006073): 50S ribosome-binding GTPase
AAA_23 (PF13476): AAA domain
238 NOTCH1suppressor240.134786.579Ank (PF00023, IPR002110, SM00248): Ankyrin repeat
EGF (PF00008, IPR000742, SM00181): EGF-like domain
EGF_2 (PF07974, IPR013111): EGF-like domain
EGF_alliinase (PF04863, IPR006947): Alliinase EGF-like domain
EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain
NOD (PF06816, IPR010660): NOTCH protein
NODP (PF07684, IPR011656): NOTCH protein
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
Notch (PF00066, IPR000800, SM00004): LNR domain
DUF3454 (PF11936, IPR024600): Domain of unknown function (DUF3454)
hEGF (PF12661, IPR013032): Human growth factor-like EGF
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
239 NPHP4interactor100.5783.404Corona_nucleoca (PF00937, IPR001218): Coronavirus nucleocapsid protein
240 NTRK1oncoprotein1320.1683831.299I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
241 NXF5interactor21.0000LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding
LRR_8 (PF13855, IPR001611): Leucine rich repeat
242 OTUB1interactor250.39360.191Peptidase_C65 (PF10275, IPR019400): Peptidase C65 Otubain
243 PABPC1oncoprotein520.355200.952RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain
YflT (PF11181, IPR025889): Heat induced stress protein YflT
244 PACSIN1interactor70.6004.001FCH (PF00611, IPR001060, SM00055): Fes/CIP4, and EFC/F-BAR homology domain
DUF2605 (PF10792, IPR019728): Protein of unknown function (DUF2605)
DUF4446 (PF14584, IPR027981): Protein of unknown function (DUF4446)
SH3_9 (PF14604, IPR001452): Variant SH3 domain
NPF (PF16601): Rabosyn-5 repeating NPF sequence-motif
245 PACSIN2oncoprotein70.8001.167DegS (PF05384, IPR008595): Sensor protein DegS
FCH (PF00611, IPR001060, SM00055): Fes/CIP4, and EFC/F-BAR homology domain
SH3BP5 (PF05276, IPR007940): SH3 domain-binding protein 5 (SH3BP5)
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
NPF (PF16601): Rabosyn-5 repeating NPF sequence-motif
246 PACSIN3interactor110.51112.973FCH (PF00611, IPR001060, SM00055): Fes/CIP4, and EFC/F-BAR homology domain
GrpE (PF01025, IPR000740): GrpE
SH3_9 (PF14604, IPR001452): Variant SH3 domain
247 PAN2interactor380.277148.116RNase_T (PF00929, IPR013520): Exonuclease
UCH_1 (PF13423, IPR001394): Ubiquitin carboxyl-terminal hydrolase
WD40_like (PF17005, IPR031544): WD40-like domain
248 PARD3interactor80.2509.283PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
DUF3534 (PF12053, IPR021922): Domain of unknown function (DUF3534)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
249 PARK2suppressor610.274485.235IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
250 PDIA3interactor180.42537.699Thioredoxin (PF00085, IPR013766): Thioredoxin
Thioredoxin_6 (PF13848): Thioredoxin-like domain
251 PIK3R2oncoprotein240.49333.974RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
PI3K_P85_iSH2 (PF16454, IPR032498): Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain
252 PLEKHG5interactor100CBM_19 (PF03427, IPR005089): Carbohydrate binding domain (family 19)
CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052)
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
UNC-79 (PF14776): Cation-channel complex subunit UNC-79
PAXIP1_C (PF15364, IPR028213): PAXIP1-associated-protein-1 C term PTIP binding protein
PH_5 (PF15405): Pleckstrin homology domain
253 PLXNB1oncoprotein40.16730.241Plexin_cytopl (PF08337, IPR013548): Plexin cytoplasmic RasGAP domain
PSI (PF01437, IPR002165, SM00423): Plexin repeat
Sema (PF01403, IPR001627, SM00630): Sema domain
TIG (PF01833, IPR002909): IPT/TIG domain
254 POC1Ainteractor50.5001.193WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
255 POLR3Dinteractor100Atrophin-1 (PF03154, IPR002951): Atrophin-1 family
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
256 POU2F1protein found in more fusions120.38211.460Pou (PF00157, IPR000327, SM00352): Pou domain - N-terminal to homeobox domain
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
DUF3597 (PF12200, IPR022016): Domain of unknown function (DUF3597)
257 POU5F1oncoprotein250.27555.324Pou (PF00157, IPR000327, SM00352): Pou domain - N-terminal to homeobox domain
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
258 PPIDinteractor160.56710.937Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
TPR_7 (PF13176, IPR019734): Tetratricopeptide repeat
259 PPME1protein found in more fusions130.36415.067Abhydrolase_6 (PF12697, IPR000073): Alpha/beta hydrolase family
260 PPP1CAsuppressor390.225241.069Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
261 PPP1CConcoprotein330.328128.845Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
262 PPP1R12Binteractor50.4004.140Mem_trans (PF03547, IPR004776): Membrane transport protein
SAE2 (PF08573, IPR013882): DNA repair protein endonuclease SAE2/CtIP C-terminus
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
263 PPP1R15Ainteractor70.5712.219FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide
Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family
EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region
PP1c_bdg (PF10488, IPR019523): Phosphatase-1 catalytic subunit binding region
SCHIP-1 (PF10148, IPR015649): Schwannomin-interacting protein 1
CAF1A (PF12253, IPR022043): Chromatin assembly factor 1 subunit A
264 PPP2R1Aoncoprotein380.313240.711TAF6_C (PF07571, IPR011442): TAF6 C-terminal HEAT repeat domain
HEAT (PF02985, IPR000357): HEAT repeat
HEAT_PBS (PF03130, IPR004155, SM00567): PBS lyase HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
265 PPP5Cinteractor190.48035.976Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
PPP5 (PF08321, IPR013235): PPP5 TPR repeat region
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_17 (PF13431): Tetratricopeptide repeat
266 PRKDCprotein found in more fusions560.238428.256FAT (PF02259, IPR003151): FAT domain
FATC (PF02260, IPR003152): FATC domain
NUC194 (PF08163, IPR012582): NUC194 domain
PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
267 PSMA2interactor260.39099.808Proteasome (PF00227, IPR001353): Proteasome subunit
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
268 PSMA3interactor390.42788.115Proteasome (PF00227, IPR001353): Proteasome subunit
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
269 PTENsuppressor290.357115.702DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain
PTEN_C2 (PF10409, IPR014020): C2 domain of PTEN tumour-suppressor protein
270 RAD23Aoncoprotein180.45617.662UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
XPC-binding (PF09280, IPR015360): XPC-binding domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
271 RAD52oncoprotein130.4705.533Rad52_Rad22 (PF04098, IPR007232): Rad52/22 family double-strand break repair protein
DUF2335 (PF10097, IPR019284): Predicted membrane protein (DUF2335)
272 RAF1oncoprotein260.40766.264Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
RBD (PF02196, IPR003116, SM00455): Raf-like Ras-binding domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
273 RBPJinteractor80.357282.935BTD (PF09270, IPR015350): Beta-trefoil DNA-binding domain
LAG1-DNAbind (PF09271, IPR015351): LAG1, DNA binding
TIG (PF01833, IPR002909): IPT/TIG domain
274 RBSNinteractor100DUF1682 (PF07946, IPR012879): Protein of unknown function (DUF1682)
FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger
Histone_HNS (PF00816, IPR001801): H-NS histone family
zf-AD (PF07776, IPR012934, SM00868): Zinc-finger associated domain (zf-AD)
Rbsn (PF11464, IPR021565): Rabenosyn Rab binding domain
DUF4637 (PF15470, IPR029174): Domain of unknown function (DUF4637)
NPF (PF16601): Rabosyn-5 repeating NPF sequence-motif
275 RBX1oncoprotein300.42483.029zf-rbx1 (PF12678, IPR024766): RING-H2 zinc finger domain
276 RELAoncoprotein300.323141.851DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain
RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
277 RFWD2suppressor170.51718.151Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein
IncA (PF04156, IPR007285): IncA protein
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
WD40_like (PF17005, IPR031544): WD40-like domain
278 RGS14interactor2022.249GoLoco (PF02188, IPR003109, SM00390): GoLoco motif
RBD (PF02196, IPR003116, SM00455): Raf-like Ras-binding domain
RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain
RGS12_us1 (PF16613): Unstructured region of RGS12
279 RGS2oncoprotein40.6670.487RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain
280 RIC3interactor30.6670.400CHASE3 (PF05227, IPR007891): CHASE3 domain
RIC3 (PF15361, IPR032763): Resistance to inhibitors of cholinesterase homologue 3
281 RNF207interactor40.8330.222AIP3 (PF03915, IPR022782, SM00806): Actin interacting protein 3
DASH_Spc34 (PF08657, IPR013966): DASH complex subunit Spc34
NOB1_Zn_bind (PF08772, IPR014881): Nin one binding (NOB1) Zn-ribbon like
zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
DUF2321 (PF10083, IPR016891): Uncharacterized protein conserved in bacteria (DUF2321)
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
DUF3583 (PF12126, IPR021978): Protein of unknown function (DUF3583)
Thioredoxin_7 (PF13899): Thioredoxin-like
282 RNPS1interactor140.45121.342RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457)
Macoilin (PF09726, IPR019130): Transmembrane protein
283 ROCK1interactor70.38176.581FPP (PF05911, IPR008587): Filament-like plant protein, long coiled-coil
ZapB (PF06005, IPR009252): Cell division protein ZapB
HR1 (PF02185, IPR011072, SM00742): Hr1 repeat
PH (PF00169, IPR001849, SM00233): PH domain
Phage_GP20 (PF06810, IPR009636): Phage minor structural protein GP20
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
Rho_Binding (PF08912, IPR015008): Rho Binding
SlyX (PF04102, IPR007236): SlyX
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding
Lzipper-MIP1 (PF14389, IPR025757): Leucine-zipper of ternary complex factor MIP1
PKcGMP_CC (PF16808, IPR031831): Coiled-coil N-terminus of cGMP-dependent protein kinase
284 RPA1suppressor540.316311.313Rep-A_N (PF04057, IPR007199): Replication factor-A protein 1, N-terminal domain
Rep_fac-A_C (PF08646, IPR013955): Replication factor-A C terminal domain
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
REPA_OB_2 (PF16900, IPR031657): Replication protein A OB domain
285 RPA2oncoprotein450.361264.732RPA_C (PF08784, IPR014892): Replication protein A C terminal
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
RMI2 (PF16100, IPR032245): RecQ-mediated genome instability protein 2
286 RPA3interactor410.353124.273Rep_fac-A_3 (PF08661, IPR013970): Replication factor A protein 3
287 RPAP1interactor60.6002.018ATP-synt_B (PF00430, IPR002146): ATP synthase B/B' CF(0)
RPAP1_C (PF08620, IPR013929): RPAP1-like, C-terminal
RPAP1_N (PF08621, IPR013930): RPAP1-like, N-terminal
288 RPL13Ainteractor310.50136.321Ribosomal_L13 (PF00572, IPR005822): Ribosomal protein L13
289 RPL18Ainteractor280.54227.679Ribosomal_L18A (PF01775, IPR023573): Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A
290 RPL7interactor480.393155.368Ribosomal_L30 (PF00327, IPR016082): Ribosomal protein L30p/L7e
Ribosomal_L30_N (PF08079, IPR012988): Ribosomal L30 N-terminal domain
291 RPL8interactor410.371124.045Ribosomal_L2 (PF00181, IPR022666): Ribosomal Proteins L2, RNA binding domain
Ribosomal_L2_C (PF03947, IPR022669): Ribosomal Proteins L2, C-terminal domain
292 RPLP0interactor550.368200.431Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
Ribosomal_L10 (PF00466, IPR001790): Ribosomal protein L10
293 RPS15Ainteractor390.43986.701Ribosomal_S8 (PF00410, IPR000630): Ribosomal protein S8
294 RPS4Xprotein found in more fusions520.394152.126KOW (PF00467, IPR005824, SM00739): KOW motif
Ribosomal_S4e (PF00900, IPR013845): Ribosomal family S4e
RS4NT (PF08071, IPR013843): RS4NT (NUC023) domain
S4 (PF01479, IPR002942, SM00363): S4 domain
40S_S4_C (PF16121, IPR032277): 40S ribosomal protein S4 C-terminus
295 RPS6KA3interactor100.4679.316Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
296 RPS6KB2interactor330.31678.625Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
297 RUVBL1oncoprotein380.276173.208TIP49 (PF06068, IPR010339): TIP49 C-terminus
298 SAMM50interactor31.0000Bac_surface_Ag (PF01103, IPR000184): Surface antigen
POTRA (PF07244, IPR010827): Surface antigen variable number repeat
299 SDHAF2oncoprotein41.0000Sdh5 (PF03937, IPR005631): Flavinator of succinate dehydrogenase
Peroxidase_2 (PF01328, IPR000028): Peroxidase, family 2
Reovirus_cap (PF00979, IPR000153): Reovirus outer capsid protein, Sigma 3
300 SEC24Cinteractor90.5003.100Gelsolin (PF00626, IPR007123): Gelsolin repeat
Sec23_BS (PF08033, IPR012990): Sec23/Sec24 beta-sandwich domain
Sec23_helical (PF04815, IPR006900): Sec23/Sec24 helical domain
Sec23_trunk (PF04811, IPR006896): Sec23/Sec24 trunk domain
zf-Sec23_Sec24 (PF04810, IPR006895): Sec23/Sec24 zinc finger
301 SEC31Ainteractor80.5365.790P3A (PF08727, IPR014838): Poliovirus 3A protein like
SRA1 (PF07304, IPR009917): Steroid receptor RNA activator (SRA1)
Sec16_C (PF12931, IPR024298): Sec23-binding domain of Sec16
Sec16 (PF12932, IPR024340): Vesicle coat trafficking protein Sec16 mid-region
302 SF3A2interactor180.38636.177Cytadhesin_P30 (PF07271, IPR009896): Cytadhesin P30/P32
PRP4 (PF08799, IPR014906): pre-mRNA processing factor 4 (PRP4) like
Totivirus_coat (PF05518, IPR008871): Totivirus coat protein
zf-met (PF12874): Zinc-finger of C2H2 type
ARL6IP6 (PF15062, IPR029383): Haemopoietic lineage transmembrane helix
SF3A2 (PF16835, IPR031781): Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11)
303 SFNsuppressor300.256550.63614-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
304 SGTAinteractor140.35224.429TOM20_plant (PF06552, IPR010547): Plant specific mitochondrial import receptor subunit TOM20
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
XPC-binding (PF09280, IPR015360): XPC-binding domain
TPR_17 (PF13431): Tetratricopeptide repeat
SGTA_dimer (PF16546, IPR032374): Homodimerisation domain of SGTA
305 SHC1oncoprotein360.41588.896PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID)
SH2 (PF00017, IPR000980, SM00252): SH2 domain
306 SHFM1protein found in more fusions200.40026.792CLLAC (PF15675, IPR031379): CLLAC-motif containing domain
307 SIRT6suppressor170.30135.108SIR2 (PF02146, IPR003000): Sir2 family
TPP_enzyme_M (PF00205, IPR012000): Thiamine pyrophosphate enzyme, central domain
308 SKIoncoprotein200.42719.189c-SKI_SMAD_bind (PF08782, IPR014890, SM01046): c-SKI Smad4 binding domain
Ski_Sno (PF02437, IPR003380): SKI/SNO/DAC family
SlyX (PF04102, IPR007236): SlyX
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
309 SKP2suppressor240.312385.435LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
LRR_2 (PF07723, IPR013101): Leucine Rich Repeat
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
F-box-like (PF12937, IPR001810): F-box-like
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
LRR_8 (PF13855, IPR001611): Leucine rich repeat
310 SLC12A3interactor70.6671.420AA_permease (PF00324, IPR004841): Amino acid permease
AA_permease_N (PF08403, IPR013612): Amino acid permease N-terminal
SLC12 (PF03522, IPR018491): Solute carrier family 12
311 SMURF1interactor290.341809.256C2 (PF00168, IPR000008, SM00239): C2 domain
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
312 SNCAinteractor290.384105.935Synuclein (PF01387, IPR001058): Synuclein
313 SNW1protein found in more fusions480.335377.762SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
SIR4_SID (PF16991, IPR031556): Sir4 SID domain
314 SOD1interactor100.5282.431Sod_Cu (PF00080, IPR001424): Copper/zinc superoxide dismutase (SODC)
315 SONinteractor90.5284.621Asp-B-Hydro_N (PF05279, IPR007943): Aspartyl beta-hydroxylase N-terminal region
G-patch (PF01585, IPR000467, SM00443): G-patch domain
tRNA_synt_1c_R2 (PF04557, IPR007638): Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2
Eapp_C (PF10238, IPR019370): E2F-associated phosphoprotein
DND1_DSRM (PF14709): double strand RNA binding domain from DEAD END PROTEIN 1
GREB1 (PF15782, IPR028422): Gene regulated by oestrogen in breast cancer
RSRP (PF17069): Arginine/Serine-Rich protein 1
316 SPRTNinteractor150.34317.303GreA_GreB (PF01272, IPR001437): Transcription elongation factor, GreA/GreB, C-term
SprT-like (PF10263, IPR006640, SM00731): SprT-like family
PRP21_like_P (PF12230, IPR022030): Pre-mRNA splicing factor PRP21 like protein
317 SRRTinteractor130.39748.560ARS2 (PF04959, IPR007042): Arsenite-resistance protein 2
DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
TRAP_alpha (PF03896, IPR005595): Translocon-associated protein (TRAP), alpha subunit
Macoilin (PF09726, IPR019130): Transmembrane protein
DUF3546 (PF12066, IPR021933): Domain of unknown function (DUF3546)
DUF4187 (PF13821, IPR025239): Domain of unknown function (DUF4187)
318 SSBP1interactor240.46259.417SSB (PF00436, IPR000424): Single-strand binding protein family
319 ST13suppressor150.50518.989Hox9_act (PF04617, IPR006711): Hox9 activation region
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat
RhoGEF67_u2 (PF16614): Unstructured region two on RhoGEF 6 and 7
320 STAU1protein found in more fusions420.377145.930dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
Staufen_C (PF16482, IPR032478): Staufen C-terminal domain
321 STIP1interactor450.294276.146TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_17 (PF13431): Tetratricopeptide repeat
Wtap (PF17098, IPR029732): Pre-mRNA-splicing regulator WTAP
322 STMN1interactor150.47614.739Stathmin (PF00836, IPR000956): Stathmin family
323 STUB1suppressor700.203986.191U-box (PF04564, IPR003613, SM00504): U-box domain
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_20 (PF14561): Tetratricopeptide repeat
324 SUGT1interactor150.39041.078CheC (PF04509, IPR007597): CheC-like family
CS (PF04969, IPR007052): CS domain
SGS (PF05002, IPR007699): SGS domain
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
TPR_16 (PF13432): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
325 SUMO2interactor160.41922.325Rad60-SLD (PF11976, IPR022617): Ubiquitin-2 like Rad60 SUMO-like
326 SYNPO2suppressor30.6670.132Calsarcin (PF05556, IPR008438): Calcineurin-binding protein (Calsarcin)
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
327