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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins ZNF790, CHP1 (from a repository: Fri Jul 19 07:45:26 2019)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)18
The number (and %) of the onco-proteins2 (11.11 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)34 (22.22 %)
The number (and %) of affected PPIs16 (47.06 %)
The number of possible different fusions1
PPI diameter4
PPI radius2
The average degree of PPI3.222
Assortativity coefficient-0.7057
The network average Clustering coefficient0.510
The number (and %) of a zero Clustering coefficients6 (33.33 %)
The number (and %) of a zero Betweenness Centrality13 (72.22 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: ZNF790,CHP1 All fusions
Proteins found in more fusions

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 ZNF790parental protein41.0000Hemocyanin_N (PF03722, IPR005204): Hemocyanin, all-alpha domain
KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-trcl (PF13451, IPR025306): Probable zinc-ribbon domain
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger
zf-C2H2_7 (PF15269): Zinc-finger
2 CHP1parental protein120.076190.000EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
3 ACDinteractor50.70039.000TPP1 (PF10341, IPR019437): Shelterin complex subunit, TPP1/ACD
4 ELAVL1oncoprotein60.40021.000RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
5 MOV10interactor100AAA_12 (PF13087): AAA domain
AAA_30 (PF13604): AAA domain
6 NXF1interactor31.0000NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain
Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding
TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain
LRR_8 (PF13855, IPR001611): Leucine rich repeat
7 POT1interactor51.0000POT1 (PF02765, IPR011564, SM00976): Telomeric single stranded DNA binding POT1/CDC13
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
POT1PC (PF16686, IPR032042): ssDNA-binding domain of telomere protection protein
8 PRSS23interactor21.0000Trypsin (PF00089, IPR001254, SM00020): Trypsin
9 SHMT2interactor100SHMT (PF00464, IPR001085): Serine hydroxymethyltransferase
10 SLC9A1interactor100DUF1427 (PF07235, IPR009872): Protein of unknown function (DUF1427)
LHC (PF00556, IPR000066): Antenna complex alpha/beta subunit
Na_H_Exchanger (PF00999, IPR006153): Sodium/hydrogen exchanger family
NEXCaM_BD (PF16644, IPR032103): Regulatory region of Na+/H+ exchanger NHE binds to calmodulin
11 SLC9A2oncoprotein100Na_H_Exchanger (PF00999, IPR006153): Sodium/hydrogen exchanger family
Sigma_reg_N (PF13800, IPR029101): Sigma factor regulator N-terminal
NEXCaM_BD (PF16644, IPR032103): Regulatory region of Na+/H+ exchanger NHE binds to calmodulin
12 SLC9A3interactor100Na_H_Exchanger (PF00999, IPR006153): Sodium/hydrogen exchanger family
NEXCaM_BD (PF16644, IPR032103): Regulatory region of Na+/H+ exchanger NHE binds to calmodulin
13 SLC9A4interactor100Na_H_Exchanger (PF00999, IPR006153): Sodium/hydrogen exchanger family
NEXCaM_BD (PF16644, IPR032103): Regulatory region of Na+/H+ exchanger NHE binds to calmodulin
14 SLC9A5interactor21.0000Na_H_Exchanger (PF00999, IPR006153): Sodium/hydrogen exchanger family
NEXCaM_BD (PF16644, IPR032103): Regulatory region of Na+/H+ exchanger NHE binds to calmodulin
15 TERF1interactor60.70039.000TRF (PF08558, IPR013867): Telomere repeat binding factor (TRF)
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
16 TINF2interactor51.0000TINF2_N (PF14973, IPR029400): TERF1-interacting nuclear factor 2 N-terminus
17 TMEM216interactor21.0000Transmemb_17 (PF09799, IPR019184): Predicted membrane protein
18 XPO1interactor50.300121.000CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region

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