Find Fusion Network

Visualization interactions

Powered by Cytoscape Web for: parental proteins KIF5B, RET (from a repository: Tue Nov 15 23:34:09 2016)

Examples AFF1 MLL ACTN4 + MLLAFF1 + MLLALK + MSNALK + TFGALK + TPM3ALK + TPM4ASXL2 + KAT6AATF1 + FUSBCR + ABL1BCR + FGFR1CCND1 + TACSTD2CD74 + ROS1CDK6 + MLLCOL1A1 + PDGFBCREB3L2 + PPARGCREB3L2 + FUSCREBBP + KAT6ADAZAP1 + MEF2DELL + MLLEPS15 + MLLERG + EWSR1ERG + FUSERG + TMPRSS2ETV5 + TMPRSS2ETV6 + ABL1ETV6 + NTRK3ETV6 + PAX5EWSR1 + FLI1EWSR1 + WT1FOXO1 + PAX3FOXP1 + PAX5FRYL + MLLGAS7 + MLLGMPS + MLLGOLGA5 + RETHOOK3 + RETHOXC13 + NUP98HOXD13 + NUP98MECOM + RUNX1MKL1 + RBM15MLL + MLLT1MLL + MLLT4MLL + MLLT10MLL + PICALMMLLT10 + PICALMNCOA1 + PAX3NIN + PDGFRBNPM1 + RARANRG1 + ODZ4NTRK1 + TFGNUMA1 + RARANUP98 + PHF23PAX5 + ZNF521PBX1 + TCF3RET + TRIM27ROS1 + SLC34A2PML + RARAPRKAR1A + RARAPRKAR1A + RETRUNX1 + RUNX1T1RUNX1 + SH3D19	Cytoscape Web will replace the contents your graph	PPI Properties: Click on nodes or edges
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Statistics and Network structure information

Statistic of PPI Value(s) The number of interactors (fusion and proteins) 141 The number (and %) of the onco-proteins 37 (26.24 %) The number (and %) of the tumor suppressors 14 (9.93 %) Total number of binary PPIs (saturation %) 766 (7.76 %) The number (and %) of affected PPIs 141 (18.41 %) The number of possible different fusions 29 PPI diameter 4 PPI radius 2 The average degree of PPI 10.142 Assortativity coefficient -0.1490 The network average Clustering coefficient 0.478 The number (and %) of a zero Clustering coefficients 11 (7.80 %) The number (and %) of a zero Betweenness Centrality 24 (17.02 %)

ACTIVE INTERACTORS MISSING INTERACTORS (in fusions)

List of the fusions
PPI for parental proteins: KIF5B,RET	All fusions : AB795253; AB795256; AB795252; HW088351; AB795250; AB795257; AB795251; HW088352; AB795255; AB795249; HW088349; HW088350; AB795254;
Proteins found in more fusions	EGFR/PTPRF (see 1 fusions); STAU1 (see 2 fusions); YWHAG (see 1 fusions); HSP90AA1 (see 2 fusions); TRIM25 (see 2 fusions); MAPK1 (see 1 fusions); CBL (see 1 fusions); GSK3B (see 1 fusions); CUL7 (see 2 fusions); HUWE1 (see 2 fusions); PSMB3 (see 1 fusions); SNAP23 (see 1 fusions); SQSTM1 (see 5 fusions); GRB2 (see 1 fusions); MARK2 (see 2 fusions); RNF168 (see 2 fusions); YWHAH (see 2 fusions); STAT3 (see 2 fusions); HNRNPD (see 1 fusions); PSMB7 (see 2 fusions); YWHAZ (see 1 fusions); EGFR (see 2 fusions); APC (see 1 fusions); KDM1A (see 2 fusions); COPS5 (see 1 fusions); SHC1 (see 1 fusions); PTK2 (see 2 fusions); EZH2 (see 1 fusions);

List of active interactors

#	Name	Type	Number of PPI (degree)	Clustering Coefficient	Betweenness Centrality	Domains (Pfam, InterPro, SMART): description
1	KIF5B	parental protein	98	0.072	8802.959	ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein Sec2p (PF06428, IPR009449): GDP/GTP exchange factor Sec2p Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain DUF3584 (PF12128, IPR021979): Protein of unknown function (DUF3584) HAUS-augmin3 (PF14932, IPR032733): HAUS augmin-like complex subunit 3 DUF4226 (PF10774, IPR019710): Domain of unknown function (DUF4226) PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
2	RET	parental protein	43	0.123	2354.478	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Cadherin (PF00028, IPR002126, SM00112): Cadherin domain
3	ABCE1	interactor	14	0.282	112.331	ABC_tran (PF00005, IPR003439): ABC transporter Fer4 (PF00037, IPR001450): 4Fe-4S binding domain RLI (PF04068, IPR007209): Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain Fer4_7 (PF12838, IPR001450): 4Fe-4S dicluster domain AAA_29 (PF13555): P-loop containing region of AAA domain
4	ACACA	interactor	9	0.389	88.304	ACC_central (PF08326, IPR013537): Acetyl-CoA carboxylase, central region Biotin_carb_C (PF02785, IPR005482, SM00878): Biotin carboxylase C-terminal domain Biotin_lipoyl (PF00364, IPR000089): Biotin-requiring enzyme Carboxyl_trans (PF01039, IPR000022): Carboxyl transferase domain Biotin_carb_N (PF00289, IPR005481): Biotin carboxylase, N-terminal domain CPSase_L_D2 (PF02786, IPR005479): Carbamoyl-phosphate synthase L chain, ATP binding domain DUF445 (PF04286, IPR007383): Protein of unknown function (DUF445)
5	AIP	suppressor	4	1.000	0	FKBP_C (PF00254, IPR001179): FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
6	AKAP2	interactor	3	0.333	23.951	DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407) AKAP2_C (PF15304, IPR029304): A-kinase anchor protein 2 C-terminus
7	APC	suppressor	11	0.311	44.148	APC_15aa (PF05972, IPR009240): APC 15 residue motif APC_basic (PF05956, IPR009234): APC basic domain APC_r (PF05923): APC repeat Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) EB1_binding (PF05937, IPR009232): EB-1 Binding Domain FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid) SAMP (PF05924, IPR009224): SAMP Motif Suppressor_APC (PF11414, IPR026831): Adenomatous polyposis coli tumour suppressor protein AIF_C (PF14721, IPR029324): Apoptosis-inducing factor, mitochondrion-associated, C-term SAS4 (PF15460, IPR029184): Something about silencing, SAS, complex subunit 4 Arm_APC_u3 (PF16629): Armadillo-associated region on APC APC_u5 (PF16630): Unstructured region on APC between 1st and 2nd catenin-bdg motifs APC_u9 (PF16633): Unstructured region on APC between 1st two creatine-rich regions APC_u13 (PF16634): Unstructured region on APC between APC_crr and SAMP APC_u14 (PF16635): Unstructured region on APC between SAMP and APC_crr APC_u15 (PF16636): Unstructured region on APC between APC_crr regions 5 and 6 APC_N_CC (PF16689, IPR032038): Coiled-coil N-terminus of APC, dimerisation domain
8	AURKB	interactor	8	0.381	20.381	Pkinase (PF00069, IPR000719): Protein kinase domain
9	AZIN1	interactor	5	1.000	0	Orn_Arg_deC_N (PF02784, IPR022644): Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC (PF00278, IPR022643): Pyridoxal-dependent decarboxylase, C-terminal sheet domain
10	BAG6	interactor	13	0.152	178.569	DUF1179 (PF06678, IPR009564): Protein of unknown function (DUF1179) Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family DUF2939 (PF11159, IPR021330): Protein of unknown function (DUF2939) DUF3538 (PF12057, IPR021925): Domain of unknown function (DUF3538) PRIMA1 (PF16101): Proline-rich membrane anchor 1
11	CAST	oncoprotein	9	0.472	56.935	Band_3_cyto (PF07565, IPR013769): Band 3 cytoplasmic domain Calpain_inhib (PF00748, IPR001259): Calpain inhibitor Maf_N (PF08383, IPR013592): Maf N-terminal region
12	CBL	suppressor	22	0.390	142.668	Cbl_N (PF02262, IPR003153): CBL proto-oncogene N-terminal domain 1 Cbl_N2 (PF02761, IPR014741): CBL proto-oncogene N-terminus, EF hand-like domain Cbl_N3 (PF02762, IPR014742): CBL proto-oncogene N-terminus, SH2-like domain UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain Prok-RING_4 (PF14447): Prokaryotic RING finger family 4 zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain
13	CBLC	oncoprotein	7	0.571	14.254	Cbl_N (PF02262, IPR003153): CBL proto-oncogene N-terminal domain 1 Cbl_N2 (PF02761, IPR014741): CBL proto-oncogene N-terminus, EF hand-like domain Cbl_N3 (PF02762, IPR014742): CBL proto-oncogene N-terminus, SH2-like domain Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
14	CDC5L	interactor	25	0.268	270.392	OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain
15	CFTR	suppressor	11	0.178	68.286	ABC_membrane (PF00664, IPR001140): ABC transporter transmembrane region ABC_tran (PF00005, IPR003439): ABC transporter Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain Rotamase_2 (PF13145, IPR000297): PPIC-type PPIASE domain CFTR_R (PF14396, IPR025837): Cystic fibrosis TM conductance regulator (CFTR), regulator domain
16	CHRNA9	interactor	3	1.000	0	Neur_chan_LBD (PF02931, IPR006202): Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
17	COPE	interactor	5	0.667	5.809	Coatomer_E (PF04733, IPR006822): Coatomer epsilon subunit TPR_19 (PF14559): Tetratricopeptide repeat
18	COPS5	protein found in more fusions	17	0.258	166.600	JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
19	CRK	oncoprotein	18	0.340	196.287	SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_2 (PF07653, IPR011511): Variant SH3 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
20	CUL7	protein found in more fusions	22	0.238	235.193	ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10) Cullin (PF00888, IPR001373, SM00182): Cullin family DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918) Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7
21	DHX9	oncoprotein	13	0.346	90.085	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold T2SSE (PF00437, IPR001482): Type II/IV secretion system protein HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2) Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
22	DIAPH1	interactor	8	0.607	11.129	APG6 (PF04111, IPR007243): Autophagy protein Apg6 Drf_DAD (PF06345, IPR010465): DRF Autoregulatory Domain Drf_FH1 (PF06346, IPR009408): Formin Homology Region 1 Drf_FH3 (PF06367, IPR010472, SM01139): Diaphanous FH3 Domain Drf_GBD (PF06371, IPR010473, SM01140): Diaphanous GTPase-binding Domain FH2 (PF02181, IPR015425, SM00498): Formin Homology 2 Domain Glucan_synthase (PF02364, IPR003440): 1,3-beta-glucan synthase component Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
23	DOK1	suppressor	9	0.821	2.936	IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type) PH (PF00169, IPR001849, SM00233): PH domain
24	DOK2	suppressor	6	0.800	1.925	IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type) PH (PF00169, IPR001849, SM00233): PH domain
25	DOK4	interactor	4	0.500	10.516	IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type) PH (PF00169, IPR001849, SM00233): PH domain
26	DOK5	interactor	2	1.000	0	IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type) PH (PF00169, IPR001849, SM00233): PH domain
27	DOK6	interactor	2	1.000	0	IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type) PH (PF00169, IPR001849, SM00233): PH domain
28	DTNB	interactor	4	0.667	1.000	EF-hand_2 (PF09068, IPR015153): EF hand EF-hand_3 (PF09069, IPR015154): EF-hand Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain Ax_dynein_light (PF10211, IPR019347): Axonemal dynein light chain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type SOGA (PF11365, IPR027881): Protein SOGA
29	DTNBP1	interactor	6	0.400	8.612	Dysbindin (PF04440, IPR007531): Dysbindin (Dystrobrevin binding protein 1) Exonuc_VII_L (PF02601, IPR020579): Exonuclease VII, large subunit DUF2730 (PF10805, IPR020269): Protein of unknown function (DUF2730)
30	EGFR	oncoprotein	33	0.224	862.680	Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT) GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
31	ELP2	interactor	4	0.500	20.360	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Lar_restr_allev (PF14354): Restriction alleviation protein Lar
32	EPB41L1	interactor	11	0.582	19.859	4_1_CTD (PF05902, IPR008379): 4.1 protein C-terminal domain (CTD)
33	EXOC7	interactor	5	0.500	36.952	Exo70 (PF03081, IPR004140): Exo70 exocyst complex subunit COG5 (PF10392, IPR019465): Golgi transport complex subunit 5
34	EZH2	suppressor	11	0.267	40.781	CDC45 (PF02724, IPR003874): CDC45-like protein TCR (PF03638, IPR005172, SM01114): Tesmin/TSO1-like CXC domain, cysteine-rich domain SET (PF00856, IPR001214, SM00317): SET domain EZH2_WD-Binding (PF11616, IPR021654): WD repeat binding protein EZH2 Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
35	FOXQ1	interactor	2	1.000	0	Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
36	FRS2	interactor	5	0.900	1.075	IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type)
37	FYCO1	interactor	3	0.667	2.592	Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger HAP1_N (PF04849, IPR006933): HAP1 N-terminal conserved region RUN (PF02759, IPR004012, SM00593): RUN domain Sec8_exocyst (PF04048, IPR007191): Sec8 exocyst complex component specific domain Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein Spectrin (PF00435, IPR002017): Spectrin repeat Syntaxin-6_N (PF09177, IPR015260): Syntaxin 6, N-terminal TSC22 (PF01166, IPR000580): TSC-22/dip/bun family bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like GOLD_2 (PF13897, IPR009038): Golgi-dynamics membrane-trafficking DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404) DUF4578 (PF15147, IPR028106): Domain of unknown function (DUF4578) HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
38	GFRA1	interactor	2	1.000	0	GDNF (PF02351, IPR016017, SM00907): GDNF/GAS1 domain
39	GRB10	oncoprotein	4	0.500	5.234	BPS (PF08947, IPR015042): BPS (Between PH and SH2) PH (PF00169, IPR001849, SM00233): PH domain RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain SH2 (PF00017, IPR000980, SM00252): SH2 domain Argos (PF11581, IPR021633): Antagonist of EGFR signalling, Argos
40	GRB2	oncoprotein	25	0.344	257.924	SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain DUF5093 (PF17011, IPR031533): Domain of unknown function (DUF5093)
41	GRB7	interactor	3	0.333	3.237	BPS (PF08947, IPR015042): BPS (Between PH and SH2) PH (PF00169, IPR001849, SM00233): PH domain RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain SH2 (PF00017, IPR000980, SM00252): SH2 domain
42	GSK3B	suppressor	13	0.167	165.966	Pkinase (PF00069, IPR000719): Protein kinase domain
43	HIST1H3A	interactor	12	0.255	112.743	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
44	HNRNPD	oncoprotein	16	0.248	123.666	CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Keratin_2_head (PF16208, IPR032444): Keratin type II head
45	HSP90AA1	oncoprotein	21	0.263	335.519	HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein
46	HUWE1	oncoprotein	21	0.284	211.014	BUD22 (PF09073, IPR015158): BUD22 DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908) DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913) FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM) Mucin (PF01456, IPR000458): Mucin-like glycoprotein Nop14 (PF04147, IPR007276): Nop14-like family PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32 RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain WWE (PF02825, IPR004170, SM00678): WWE domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54 U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414)
47	ICE2	interactor	3	1.000	0	NARG2_C (PF10505, IPR019535): NMDA receptor-regulated gene protein 2 C-terminus CLAMP (PF14769, IPR032727): Flagellar C1a complex subunit C1a-32
48	IKBKG	interactor	10	0.333	60.708	CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H) DUF725 (PF05267, IPR007931): Protein of unknown function (DUF725) NEMO (PF11577, IPR021063): NF-kappa-B essential modulator NEMO LLC1 (PF14945, IPR020339): Normal lung function maintenance, Low in Lung Cancer 1 protein CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator
49	KDM1A	protein found in more fusions	13	0.167	272.665	Amino_oxidase (PF01593, IPR002937): Flavin containing amine oxidoreductase CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain SWIRM (PF04433, IPR007526): SWIRM domain DUF4298 (PF14131, IPR025384): Domain of unknown function (DUF4298)
50	KIAA0368	interactor	10	0.289	142.320	HEAT (PF02985, IPR000357): HEAT repeat IFRD (PF05004, IPR007701): Interferon-related developmental regulator (IFRD) CLASP_N (PF12348, IPR024395): CLASP N terminal MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region Sec7_N (PF12783, IPR032691): Guanine nucleotide exchange factor in Golgi transport N-terminal Ecm29 (PF13001, IPR024372): Proteasome stabiliser HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats
51	KIDINS220	interactor	2	1.000	0	KAP_NTPase (PF07693, IPR011646): KAP family P-loop domain SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif) Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_5 (PF13857): Ankyrin repeats (many copies)
52	KIF1A	interactor	6	0.267	87.804	FHA (PF00498, IPR000253, SM00240): FHA domain IncA (PF04156, IPR007285): IncA protein PH (PF00169, IPR001849, SM00233): PH domain Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain KIF1B (PF12423, IPR022140): Kinesin protein 1B Sox_N (PF12444, IPR022151): Sox developmental protein N terminal DUF3694 (PF12473, IPR022164): Kinesin protein Kinesin_assoc (PF16183, IPR032405): Kinesin-associated
53	KIF5C	interactor	14	0.451	58.032	DivIC (PF04977, IPR007060): Septum formation initiator DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) Cnn_1N (PF07989, IPR012943): Centrosomin N-terminal motif 1 Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain Hrs_helical (PF12210, IPR024641): Hepatocyte growth factor-regulated tyrosine kinase substrate DUF4226 (PF10774, IPR019710): Domain of unknown function (DUF4226) PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
54	KLC1	interactor	22	0.346	201.619	Gly_radical (PF01228, IPR001150): Glycine radical SOGA (PF11365, IPR027881): Protein SOGA TPR_10 (PF13374, IPR011990): Tetratricopeptide repeat TPR_12 (PF13424): Tetratricopeptide repeat JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II
55	KLC2	interactor	22	0.338	180.417	TPR_10 (PF13374, IPR011990): Tetratricopeptide repeat TPR_12 (PF13424): Tetratricopeptide repeat JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II
56	KLC3	interactor	12	0.436	39.395	TPR_4 (PF07721, IPR011717): Tetratricopeptide repeat TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding TPR_12 (PF13424): Tetratricopeptide repeat
57	KLC4	interactor	20	0.395	121.243	Flagellin_N (PF00669, IPR001029): Bacterial flagellin N-terminal helical region Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region TPR_10 (PF13374, IPR011990): Tetratricopeptide repeat TPR_12 (PF13424): Tetratricopeptide repeat LUD_dom (PF02589): LUD domain
58	KPTN	interactor	6	0.733	2.667	AcetylCoA_hyd_C (PF13336, IPR026888): Acetyl-CoA hydrolase/transferase C-terminal domain VCBS (PF13517): Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella BBS2_Mid (PF14783, IPR029429): Ciliary BBSome complex subunit 2, middle region
59	KYNU	interactor	3	0	20.465	Aminotran_5 (PF00266, IPR000192): Aminotransferase class-V CaKB (PF03185, IPR003930): Calcium-activated potassium channel, beta subunit
60	L1TD1	interactor	2	1.000	0	FlaC_arch (PF05377, IPR008039): Flagella accessory protein C (FlaC) Occludin_ELL (PF07303, IPR010844): Occludin homology domain PDEase_I (PF00233, IPR002073): 3'5'-cyclic nucleotide phosphodiesterase Transposase_22 (PF02994, IPR004244): L1 transposable element
61	LSM2	interactor	2	1.000	0	LSM (PF01423, IPR001163): LSM domain
62	MAPK1	oncoprotein	12	0.273	83.901	Pkinase (PF00069, IPR000719): Protein kinase domain
63	MAPK3	oncoprotein	6	0.300	22.856	Pkinase (PF00069, IPR000719): Protein kinase domain
64	MARK2	protein found in more fusions	13	0.667	14.078	DUF702 (PF05142, IPR007818): Domain of unknown function (DUF702) KA1 (PF02149, IPR001772): Kinase associated domain 1 Pkinase (PF00069, IPR000719): Protein kinase domain UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
65	MCCC1	interactor	3	1.000	0	Biotin_carb_C (PF02785, IPR005482, SM00878): Biotin carboxylase C-terminal domain Biotin_lipoyl (PF00364, IPR000089): Biotin-requiring enzyme Biotin_carb_N (PF00289, IPR005481): Biotin carboxylase, N-terminal domain CPSase_L_D2 (PF02786, IPR005479): Carbamoyl-phosphate synthase L chain, ATP binding domain
66	MCRS1	interactor	3	0	24.116	FHA (PF00498, IPR000253, SM00240): FHA domain MCRS_N (PF13325, IPR025999): N-terminal region of micro-spherule protein
67	MED4	interactor	10	0.178	114.782	Med4 (PF10018, IPR019258): Vitamin-D-receptor interacting Mediator subunit 4
68	MEPCE	interactor	8	0.393	51.567	Bin3 (PF06859, IPR010675): Bicoid-interacting protein 3 (Bin3) Methyltransf_23 (PF13489): Methyltransferase domain FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 DLEU7 (PF15760, IPR031510): Leukemia-associated protein 7
69	NCOR1	oncoprotein	5	0.500	18.372	BES1_N (PF05687, IPR008540): BES1/BZR1 plant transcription factor, N-terminal Lamp (PF01299, IPR002000): Lysosome-associated membrane glycoprotein (Lamp) MAS20 (PF02064, IPR002056): MAS20 protein import receptor Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region Eapp_C (PF10238, IPR019370): E2F-associated phosphoprotein Hid1 (PF12722): High-temperature-induced dauer-formation protein Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) GPS2_interact (PF15784, IPR031557): G-protein pathway suppressor 2-interacting domain DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834) RBR (PF17208): RNA binding Region
70	NDRG1	suppressor	3	0	58.653	Ndr (PF03096, IPR004142): Ndr family
71	NHS	interactor	8	0.214	111.954	Radial_spoke_3 (PF06098, IPR009290): Radial spoke protein 3 NHS (PF15273, IPR024845): NHS-like
72	NME2	interactor	3	1.000	0	NDK (PF00334, IPR001564, SM00562): Nucleoside diphosphate kinase
73	NOTCH2NL	interactor	3	0	8.439	EGF (PF00008, IPR000742, SM00181): EGF-like domain EGF_alliinase (PF04863, IPR006947): Alliinase EGF-like domain EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
74	NOTCH3	suppressor	4	0.500	6.508	Ank (PF00023, IPR002110, SM00248): Ankyrin repeat EGF (PF00008, IPR000742, SM00181): EGF-like domain EGF_alliinase (PF04863, IPR006947): Alliinase EGF-like domain EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain NOD (PF06816, IPR010660): NOTCH protein NODP (PF07684, IPR011656): NOTCH protein Notch (PF00066, IPR000800, SM00004): LNR domain DUF3454 (PF11936, IPR024600): Domain of unknown function (DUF3454) hEGF (PF12661, IPR013032): Human growth factor-like EGF cEGF (PF12662, IPR026823): Complement Clr-like EGF-like Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_5 (PF13857): Ankyrin repeats (many copies)
75	NRTN	interactor	2	1.000	0	TGF_beta (PF00019, IPR001839, SM00204): Transforming growth factor beta like domain
76	NTRK1	oncoprotein	67	0.129	3313.796	I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
77	NUP43	interactor	6	0.533	3.952	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
78	NUP50	interactor	6	0.533	13.667	NUP50 (PF08911, IPR015007): NUP50 (Nucleoporin 50 kDa) Ran_BP1 (PF00638, IPR000156, SM00160): RanBP1 domain
79	OGT	interactor	5	0.600	12.138	TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_11 (PF13414, IPR011990): TPR repeat TPR_12 (PF13424): Tetratricopeptide repeat Glyco_transf_41 (PF13844, IPR029489): Glycosyl transferase family 41 TPR_19 (PF14559): Tetratricopeptide repeat
80	PDLIM7	interactor	7	0.286	73.430	LIM (PF00412, IPR001781, SM00132): LIM domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) zinc_ribbon_10 (PF10058, IPR019273): Predicted integral membrane zinc-ribbon metal-binding protein DUF4749 (PF15936, IPR031847): Domain of unknown function (DUF4749)
81	PLCG1	oncoprotein	10	0.778	13.671	C2 (PF00168, IPR000008, SM00239): C2 domain PH (PF00169, IPR001849, SM00233): PH domain SH2 (PF00017, IPR000980, SM00252): SH2 domain PI-PLC-X (PF00388, IPR000909, SM00148): Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y (PF00387, IPR001711, SM00149): Phosphatidylinositol-specific phospholipase C, Y domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain PH_12 (PF16457, IPR001849): Pleckstrin homology domain
82	POU1F1	interactor	2	1.000	0	Pou (PF00157, IPR000327, SM00352): Pou domain - N-terminal to homeobox domain Homeobox (PF00046, IPR001356, SM00389): Homeobox domain Lsr2 (PF11774, IPR024412): Lsr2
83	PPP4R3B	interactor	10	0.444	120.603	Diphtheria_T (PF02764, IPR022405): Diphtheria toxin, T domain SMK-1 (PF04802, IPR006887): Component of IIS longevity pathway SMK-1 IGF2_C (PF08365, IPR013576): Insulin-like growth factor II E-peptide WH1 (PF00568, IPR000697, SM00461): WH1 domain
84	PRKAR2B	interactor	2	1.000	0	RIIa (PF02197, IPR003117, SM00394): Regulatory subunit of type II PKA R-subunit cNMP_binding (PF00027, IPR000595, SM00100): Cyclic nucleotide-binding domain
85	PSMA2	interactor	17	0.467	90.906	Proteasome (PF00227, IPR001353): Proteasome subunit Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
86	PSMA4	interactor	12	0.742	22.541	Proteasome (PF00227, IPR001353): Proteasome subunit U79_P34 (PF03064, IPR004138): HSV U79 / HCMV P34 Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
87	PSMA5	oncoprotein	16	0.492	63.545	Proteasome (PF00227, IPR001353): Proteasome subunit Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
88	PSMB3	protein found in more fusions	14	0.641	18.742	Proteasome (PF00227, IPR001353): Proteasome subunit
89	PSMB4	interactor	11	0.764	7.184	Integrin_b_cyt (PF08725, IPR014836): Integrin beta cytoplasmic domain Proteasome (PF00227, IPR001353): Proteasome subunit
90	PSMB5	interactor	11	0.709	29.091	Proteasome (PF00227, IPR001353): Proteasome subunit
91	PSMB6	interactor	11	0.636	39.210	DUF1502 (PF07397, IPR010871): Repeat of unknown function (DUF1502) Proteasome (PF00227, IPR001353): Proteasome subunit
92	PSMB7	protein found in more fusions	14	0.667	15.204	Proteasome (PF00227, IPR001353): Proteasome subunit Pr_beta_C (PF12465, IPR024689): Proteasome beta subunits C terminal
93	PSME1	interactor	10	0.694	29.797	PA28_alpha (PF02251, IPR003185): Proteasome activator pa28 alpha subunit PA28_beta (PF02252, IPR003186): Proteasome activator pa28 beta subunit RNase_H2-Ydr279 (PF09468, IPR019024): Ydr279p protein family (RNase H2 complex component)
94	PTK2	protein found in more fusions	17	0.425	138.798	FERM_M (PF00373, IPR019748): FERM central domain Focal_AT (PF03623, IPR005189): Focal adhesion targeting region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase UCMA (PF17085, IPR031386): Unique cartilage matrix associated protein
95	PTPN23	suppressor	9	0.500	115.060	BRO1 (PF03097, IPR004328, SM01041): BRO1-like domain Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase SOGA (PF11365, IPR027881): Protein SOGA ALIX_LYPXL_bnd (PF13949, IPR025304): ALIX V-shaped domain binding to HIV
96	PTPRF	protein found in more fusions	6	0.533	15.767	Arylsulfotrans (PF05935, IPR010262): Arylsulfotransferase (ASST) C2-set_2 (PF08205, IPR013162): CD80-like C2-set immunoglobulin domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase DUF3377 (PF11857, IPR021805): Domain of unknown function (DUF3377)
97	RABGAP1	interactor	4	0.667	11.596	DUF11 (PF01345, IPR001434): Domain of unknown function DUF11 fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase (PF00069, IPR000719): Protein kinase domain PPAK (PF02818, IPR004168): PPAK motif Titin_Z (PF09042, IPR015129): Titin Z V-set (PF07686, IPR013106): Immunoglobulin V-set domain Y_Y_Y (PF07495, IPR011123): Y_Y_Y domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) Ig_3 (PF13927): Immunoglobulin domain
98	RANBP2	oncoprotein	11	0.333	28.884	Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat Ran_BP1 (PF00638, IPR000156, SM00160): RanBP1 domain zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others DUF2693 (PF10902, IPR024401): Protein of unknown function (DUF2693) IR1-M (PF12185, IPR022011): Nup358/RanBP2 E3 ligase domain Dmrt1 (PF12374, IPR022114): Double-sex mab3 related transcription factor 1 TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat TPR_11 (PF13414, IPR011990): TPR repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat
99	RAPGEF2	interactor	1	0	0	PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain RasGEF (PF00617, IPR001895, SM00147): RasGEF domain RasGEF_N (PF00618, IPR000651, SM00229): RasGEF N-terminal motif cNMP_binding (PF00027, IPR000595, SM00100): Cyclic nucleotide-binding domain
100	RNF168	protein found in more fusions	4	0.667	0.867	ATP-synt_E (PF05680, IPR008386): ATP synthase E chain DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407) Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
101	RNF20	interactor	5	1.000	0	Allexi_40kDa (PF05549, IPR008398): Allexivirus 40kDa protein Atrophin-1 (PF03154, IPR002951): Atrophin-1 family BRE1 (PF08647, IPR013956): BRE1 E3 ubiquitin ligase DUF1690 (PF07956, IPR012471): Protein of Unknown function (DUF1690) HrpB7 (PF09486, IPR013392): Bacterial type III secretion protein (HrpB7) Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP) Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region Sox_N (PF12444, IPR022151): Sox developmental protein N terminal DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200) zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407) Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion
102	RPS6KB2	interactor	7	0.381	49.026	Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
103	SFN	suppressor	16	0.390	228.769	14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
104	SGF29	interactor	4	0.500	4.071	DUF1325 (PF07039, IPR010750): SGF29 tudor-like domain Filament (PF00038, IPR001664): Intermediate filament protein
105	SGTB	interactor	4	0.333	12.451	TOM20_plant (PF06552, IPR010547): Plant specific mitochondrial import receptor subunit TOM20 TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat XPC-binding (PF09280, IPR015360): XPC-binding domain TPR_11 (PF13414, IPR011990): TPR repeat SGTA_dimer (PF16546, IPR032374): Homodimerisation domain of SGTA
106	SHC1	oncoprotein	17	0.458	114.669	PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) SH2 (PF00017, IPR000980, SM00252): SH2 domain
107	SIRT7	interactor	15	0.171	129.385	DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563) SIR2 (PF02146, IPR003000): Sir2 family
108	SLC38A10	interactor	1	0	0	Aa_trans (PF01490, IPR004758): Transmembrane amino acid transporter protein DUF2304 (PF10066, IPR019277): Uncharacterized conserved protein (DUF2304)
109	SNAP23	protein found in more fusions	5	0.333	16.942	DivIC (PF04977, IPR007060): Septum formation initiator DUF16 (PF01519, IPR002862): Protein of unknown function DUF16 SNAP-25 (PF00835, IPR000928): SNAP-25 family DUF5089 (PF17002, IPR031547): Domain of unknown function (DUF5089)
110	SNAP25	interactor	1	0	0	SNAP-25 (PF00835, IPR000928): SNAP-25 family Use1 (PF09753, IPR019150): Membrane fusion protein Use1
111	SORT1	interactor	6	0.467	69.625	Sortilin_C (PF15901, IPR031777): Sortilin, neurotensin receptor 3, C-terminal Sortilin-Vps10 (PF15902, IPR031778): Sortilin, neurotensin receptor 3
112	SPG20	interactor	3	0.667	0.400	MIT (PF04212, IPR007330, SM00745): MIT (microtubule interacting and transport) domain Senescence (PF06911, IPR009686): Senescence-associated protein
113	SQSTM1	oncoprotein	11	0.289	75.999	PB1 (PF00564, IPR000270, SM00666): PB1 domain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type UBA_5 (PF16577, IPR015940): UBA domain
114	SRC	oncoprotein	18	0.404	140.746	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
115	SRP68	interactor	7	0.524	8.557	RhlB (PF12300, IPR022077): ATP-dependent RNA helicase RhlB SRP68 (PF16969, IPR026258): RNA-binding signal recognition particle 68
116	STAT3	suppressor	14	0.372	113.105	SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain
117	STAU1	protein found in more fusions	15	0.440	51.251	dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif Staufen_C (PF16482, IPR032478): Staufen C-terminal domain
118	SYNCRIP	interactor	15	0.248	314.090	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 (PF11608, IPR024582): Limkain b1
119	SYNE4	interactor	7	0.714	4.806	KASH (PF10541, IPR012315): Nuclear envelope localisation domain
120	TAX1BP1	interactor	5	0.300	35.333	CALCOCO1 (PF07888, IPR012852): Calcium binding and coiled-coil domain (CALCOCO1) like zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain PolyA_pol (PF01743, IPR002646): Poly A polymerase head domain Spc24 (PF08286, IPR013252): Spc24 subunit of Ndc80 zf-C2H2_4 (PF13894): C2H2-type zinc finger PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
121	TRAK1	interactor	4	0.667	2.101	HAP1_N (PF04849, IPR006933): HAP1 N-terminal conserved region Spc24 (PF08286, IPR013252): Spc24 subunit of Ndc80 Milton (PF12448, IPR022154): Kinesin associated protein
122	TRAK2	interactor	8	0.500	13.756	ZapB (PF06005, IPR009252): Cell division protein ZapB HAP1_N (PF04849, IPR006933): HAP1 N-terminal conserved region Milton (PF12448, IPR022154): Kinesin associated protein
123	TRIM25	protein found in more fusions	7	0.400	9.638	Fes1 (PF08609, IPR013918): Nucleotide exchange factor Fes1 Pox_Rif (PF03340, IPR005008): Poxvirus rifampicin resistance protein SPRY (PF00622, IPR003877, SM00449): SPRY domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
124	TRIP6	interactor	10	0.267	149.465	DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region LIM (PF00412, IPR001781, SM00132): LIM domain
125	TUBA1A	oncoprotein	15	0.333	142.749	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
126	TWF1	interactor	4	0.833	0.518	Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein
127	TXNL4A	interactor	2	1.000	0	DIM1 (PF02966, IPR004123): Mitosis protein DIM1
128	USPL1	interactor	1	0	0	zinc_ribbon_2 (PF13240, IPR026870): zinc-ribbon domain Peptidase_C98 (PF15499, IPR028890): Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF4650 (PF15509, IPR029388): Domain of unknown function (DUF4650)
129	VDAC1	interactor	5	0.400	63.676	Porin_3 (PF01459, IPR027246): Eukaryotic porin
130	VPS52	interactor	5	0.333	54.783	Vps52 (PF04129, IPR007258): Vps52 / Sac2 family COG5 (PF10392, IPR019465): Golgi transport complex subunit 5 Sec3_C (PF09763, IPR019160): Exocyst complex component Sec3
131	XPR1	interactor	2	1.000	0	EXS (PF03124, IPR004342): EXS family SPX (PF03105, IPR004331): SPX domain
132	YWHAB	interactor	17	0.544	97.548	14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein Virulence_fact (PF13769, IPR025989): Virulence factor
133	YWHAE	oncoprotein	20	0.479	175.461	14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
134	YWHAG	protein found in more fusions	22	0.486	93.522	14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
135	YWHAH	protein found in more fusions	16	0.505	53.623	14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
136	YWHAQ	interactor	25	0.390	183.935	14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
137	YWHAZ	protein found in more fusions	25	0.395	171.941	14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
138	ZBTB48	suppressor	3	0	35.779	BTB (PF00651, IPR013069, SM00225): BTB/POZ domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
139	ZBTB8A	interactor	3	0	106.529	BTB (PF00651, IPR013069, SM00225): BTB/POZ domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zinc_ribbon_10 (PF10058, IPR019273): Predicted integral membrane zinc-ribbon metal-binding protein Zn_Tnp_IS1595 (PF12760, IPR024442): Transposase zinc-ribbon domain zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger
140	ZBTB8B	interactor	1	0	0	BTB (PF00651, IPR013069, SM00225): BTB/POZ domain Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain zf-C2H2_11 (PF16622, IPR007087): zinc-finger C2H2-type
141	ZCCHC8	interactor	5	0.200	45.397	Herpes_BLRF2 (PF05812, IPR008642): Herpesvirus BLRF2 protein PSP (PF04046, IPR006568, SM00581): PSP zf-CCHC (PF00098, IPR001878): Zinc knuckle DUF4140 (PF13600, IPR025554): N-terminal domain of unknown function (DUF4140)

B a c k    t o    T o p ⇑

List of missing interactors (in fusions)

#	Name	Type	Domains (Pfam, InterPro, SMART): description	Fusion(s)
1	ACACA	interactor	ACC_central (PF08326, IPR013537): Acetyl-CoA carboxylase, central region Biotin_carb_C (PF02785, IPR005482, SM00878): Biotin carboxylase C-terminal domain Biotin_lipoyl (PF00364, IPR000089): Biotin-requiring enzyme Carboxyl_trans (PF01039, IPR000022): Carboxyl transferase domain Biotin_carb_N (PF00289, IPR005481): Biotin carboxylase, N-terminal domain CPSase_L_D2 (PF02786, IPR005479): Carbamoyl-phosphate synthase L chain, ATP binding domain DUF445 (PF04286, IPR007383): Protein of unknown function (DUF445)	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
2	AKAP2	interactor	DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407) AKAP2_C (PF15304, IPR029304): A-kinase anchor protein 2 C-terminus	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
3	AZIN1	interactor	Orn_Arg_deC_N (PF02784, IPR022644): Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC (PF00278, IPR022643): Pyridoxal-dependent decarboxylase, C-terminal sheet domain	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
4	CAST	oncoprotein	Band_3_cyto (PF07565, IPR013769): Band 3 cytoplasmic domain Calpain_inhib (PF00748, IPR001259): Calpain inhibitor Maf_N (PF08383, IPR013592): Maf N-terminal region	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
5	CDC5L	interactor	OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain	AB795249, AB795250, HW088349
6	CFTR	suppressor	ABC_membrane (PF00664, IPR001140): ABC transporter transmembrane region ABC_tran (PF00005, IPR003439): ABC transporter Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain Rotamase_2 (PF13145, IPR000297): PPIC-type PPIASE domain CFTR_R (PF14396, IPR025837): Cystic fibrosis TM conductance regulator (CFTR), regulator domain	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
7	CHRNA9	interactor	Neur_chan_LBD (PF02931, IPR006202): Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
8	COPE	interactor	Coatomer_E (PF04733, IPR006822): Coatomer epsilon subunit TPR_19 (PF14559): Tetratricopeptide repeat	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
9	COPS5	interactor	JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease	AB795249, AB795250, HW088349
10	CUL7	interactor	ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10) Cullin (PF00888, IPR001373, SM00182): Cullin family DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918) Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7	AB795249, AB795250, HW088349
11	DIAPH1	interactor	APG6 (PF04111, IPR007243): Autophagy protein Apg6 Drf_DAD (PF06345, IPR010465): DRF Autoregulatory Domain Drf_FH1 (PF06346, IPR009408): Formin Homology Region 1 Drf_FH3 (PF06367, IPR010472, SM01139): Diaphanous FH3 Domain Drf_GBD (PF06371, IPR010473, SM01140): Diaphanous GTPase-binding Domain FH2 (PF02181, IPR015425, SM00498): Formin Homology 2 Domain Glucan_synthase (PF02364, IPR003440): 1,3-beta-glucan synthase component Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
12	DTNBP1	interactor	Dysbindin (PF04440, IPR007531): Dysbindin (Dystrobrevin binding protein 1) Exonuc_VII_L (PF02601, IPR020579): Exonuclease VII, large subunit DUF2730 (PF10805, IPR020269): Protein of unknown function (DUF2730)	AB795249, AB795250, HW088349
13	ELP2	interactor	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Lar_restr_allev (PF14354): Restriction alleviation protein Lar	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
14	EPB41L1	interactor	4_1_CTD (PF05902, IPR008379): 4.1 protein C-terminal domain (CTD)	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
15	EXOC7	interactor	Exo70 (PF03081, IPR004140): Exo70 exocyst complex subunit COG5 (PF10392, IPR019465): Golgi transport complex subunit 5	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
16	EZH2	suppressor	CDC45 (PF02724, IPR003874): CDC45-like protein TCR (PF03638, IPR005172, SM01114): Tesmin/TSO1-like CXC domain, cysteine-rich domain SET (PF00856, IPR001214, SM00317): SET domain EZH2_WD-Binding (PF11616, IPR021654): WD repeat binding protein EZH2 Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
17	FOXQ1	interactor	Forkhead (PF00250, IPR001766, SM00339): Forkhead domain	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
18	GFRA1	interactor	GDNF (PF02351, IPR016017, SM00907): GDNF/GAS1 domain	AB795249, AB795250, AB795251, AB795252, AB795253, AB795254, AB795255, AB795256, AB795257, HW088349, HW088350, HW088351, HW088352
19	ICE2	interactor	NARG2_C (PF10505, IPR019535): NMDA receptor-regulated gene protein 2 C-terminus CLAMP (PF14769, IPR032727): Flagellar C1a complex subunit C1a-32	AB795249, AB795250, AB795251, AB795252, AB795253, AB795254, AB795255, AB795256, AB795257, HW088349, HW088350, HW088351, HW088352
20	KIAA0368	interactor	HEAT (PF02985, IPR000357): HEAT repeat IFRD (PF05004, IPR007701): Interferon-related developmental regulator (IFRD) CLASP_N (PF12348, IPR024395): CLASP N terminal MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region Sec7_N (PF12783, IPR032691): Guanine nucleotide exchange factor in Golgi transport N-terminal Ecm29 (PF13001, IPR024372): Proteasome stabiliser HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats	AB795249, AB795250, HW088349
21	KIDINS220	interactor	KAP_NTPase (PF07693, IPR011646): KAP family P-loop domain SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif) Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_5 (PF13857): Ankyrin repeats (many copies)	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
22	KIF5B	parental protein	ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein Sec2p (PF06428, IPR009449): GDP/GTP exchange factor Sec2p Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain DUF3584 (PF12128, IPR021979): Protein of unknown function (DUF3584) HAUS-augmin3 (PF14932, IPR032733): HAUS augmin-like complex subunit 3 DUF4226 (PF10774, IPR019710): Domain of unknown function (DUF4226) PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain	AB795249, AB795250, AB795251, AB795252, AB795253, AB795254, AB795255, AB795256, AB795257, HW088349, HW088350, HW088351, HW088352
23	KIF5C	interactor	DivIC (PF04977, IPR007060): Septum formation initiator DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) Cnn_1N (PF07989, IPR012943): Centrosomin N-terminal motif 1 Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain Hrs_helical (PF12210, IPR024641): Hepatocyte growth factor-regulated tyrosine kinase substrate DUF4226 (PF10774, IPR019710): Domain of unknown function (DUF4226) PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain	AB795249, AB795250, HW088349
24	KLC1	interactor	Gly_radical (PF01228, IPR001150): Glycine radical SOGA (PF11365, IPR027881): Protein SOGA TPR_10 (PF13374, IPR011990): Tetratricopeptide repeat TPR_12 (PF13424): Tetratricopeptide repeat JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
25	KLC2	interactor	TPR_10 (PF13374, IPR011990): Tetratricopeptide repeat TPR_12 (PF13424): Tetratricopeptide repeat JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
26	KLC3	interactor	TPR_4 (PF07721, IPR011717): Tetratricopeptide repeat TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding TPR_12 (PF13424): Tetratricopeptide repeat	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
27	KLC4	interactor	Flagellin_N (PF00669, IPR001029): Bacterial flagellin N-terminal helical region Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region TPR_10 (PF13374, IPR011990): Tetratricopeptide repeat TPR_12 (PF13424): Tetratricopeptide repeat LUD_dom (PF02589): LUD domain	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
28	KPTN	interactor	AcetylCoA_hyd_C (PF13336, IPR026888): Acetyl-CoA hydrolase/transferase C-terminal domain VCBS (PF13517): Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella BBS2_Mid (PF14783, IPR029429): Ciliary BBSome complex subunit 2, middle region	AB795249, AB795250, AB795251, AB795252, AB795253, AB795254, AB795255, AB795256, AB795257, HW088349, HW088350, HW088351, HW088352
29	L1TD1	interactor	FlaC_arch (PF05377, IPR008039): Flagella accessory protein C (FlaC) Occludin_ELL (PF07303, IPR010844): Occludin homology domain PDEase_I (PF00233, IPR002073): 3'5'-cyclic nucleotide phosphodiesterase Transposase_22 (PF02994, IPR004244): L1 transposable element	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
30	LSM2	interactor	LSM (PF01423, IPR001163): LSM domain	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
31	MARK2	interactor	DUF702 (PF05142, IPR007818): Domain of unknown function (DUF702) KA1 (PF02149, IPR001772): Kinase associated domain 1 Pkinase (PF00069, IPR000719): Protein kinase domain UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain	AB795249, AB795250, HW088349
32	MCCC1	interactor	Biotin_carb_C (PF02785, IPR005482, SM00878): Biotin carboxylase C-terminal domain Biotin_lipoyl (PF00364, IPR000089): Biotin-requiring enzyme Biotin_carb_N (PF00289, IPR005481): Biotin carboxylase, N-terminal domain CPSase_L_D2 (PF02786, IPR005479): Carbamoyl-phosphate synthase L chain, ATP binding domain	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
33	MED4	interactor	Med4 (PF10018, IPR019258): Vitamin-D-receptor interacting Mediator subunit 4	AB795249, AB795250, HW088349
34	MEPCE	interactor	Bin3 (PF06859, IPR010675): Bicoid-interacting protein 3 (Bin3) Methyltransf_23 (PF13489): Methyltransferase domain FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 DLEU7 (PF15760, IPR031510): Leukemia-associated protein 7	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
35	NCOR1	oncoprotein	BES1_N (PF05687, IPR008540): BES1/BZR1 plant transcription factor, N-terminal Lamp (PF01299, IPR002000): Lysosome-associated membrane glycoprotein (Lamp) MAS20 (PF02064, IPR002056): MAS20 protein import receptor Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region Eapp_C (PF10238, IPR019370): E2F-associated phosphoprotein Hid1 (PF12722): High-temperature-induced dauer-formation protein Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) GPS2_interact (PF15784, IPR031557): G-protein pathway suppressor 2-interacting domain DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834) RBR (PF17208): RNA binding Region	AB795249, AB795250, HW088349
36	NDRG1	suppressor	Ndr (PF03096, IPR004142): Ndr family	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
37	NHS	interactor	Radial_spoke_3 (PF06098, IPR009290): Radial spoke protein 3 NHS (PF15273, IPR024845): NHS-like	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
38	NME2	interactor	NDK (PF00334, IPR001564, SM00562): Nucleoside diphosphate kinase	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
39	NUP50	interactor	NUP50 (PF08911, IPR015007): NUP50 (Nucleoporin 50 kDa) Ran_BP1 (PF00638, IPR000156, SM00160): RanBP1 domain	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
40	OGT	interactor	TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_11 (PF13414, IPR011990): TPR repeat TPR_12 (PF13424): Tetratricopeptide repeat Glyco_transf_41 (PF13844, IPR029489): Glycosyl transferase family 41 TPR_19 (PF14559): Tetratricopeptide repeat	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
41	POU1F1	interactor	Pou (PF00157, IPR000327, SM00352): Pou domain - N-terminal to homeobox domain Homeobox (PF00046, IPR001356, SM00389): Homeobox domain Lsr2 (PF11774, IPR024412): Lsr2	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
42	PPP4R3B	interactor	Diphtheria_T (PF02764, IPR022405): Diphtheria toxin, T domain SMK-1 (PF04802, IPR006887): Component of IIS longevity pathway SMK-1 IGF2_C (PF08365, IPR013576): Insulin-like growth factor II E-peptide WH1 (PF00568, IPR000697, SM00461): WH1 domain	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
43	PRKAR2B	interactor	RIIa (PF02197, IPR003117, SM00394): Regulatory subunit of type II PKA R-subunit cNMP_binding (PF00027, IPR000595, SM00100): Cyclic nucleotide-binding domain	AB795249, AB795250, HW088349
44	PSMA2	interactor	Proteasome (PF00227, IPR001353): Proteasome subunit Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
45	PSMA4	interactor	Proteasome (PF00227, IPR001353): Proteasome subunit U79_P34 (PF03064, IPR004138): HSV U79 / HCMV P34 Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
46	PSMA5	oncoprotein	Proteasome (PF00227, IPR001353): Proteasome subunit Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
47	PSMB3	interactor	Proteasome (PF00227, IPR001353): Proteasome subunit	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
48	PSMB4	interactor	Integrin_b_cyt (PF08725, IPR014836): Integrin beta cytoplasmic domain Proteasome (PF00227, IPR001353): Proteasome subunit	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
49	PSMB5	interactor	Proteasome (PF00227, IPR001353): Proteasome subunit	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
50	PSMB6	interactor	DUF1502 (PF07397, IPR010871): Repeat of unknown function (DUF1502) Proteasome (PF00227, IPR001353): Proteasome subunit	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
51	PSMB7	interactor	Proteasome (PF00227, IPR001353): Proteasome subunit Pr_beta_C (PF12465, IPR024689): Proteasome beta subunits C terminal	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
52	PSME1	interactor	PA28_alpha (PF02251, IPR003185): Proteasome activator pa28 alpha subunit PA28_beta (PF02252, IPR003186): Proteasome activator pa28 beta subunit RNase_H2-Ydr279 (PF09468, IPR019024): Ydr279p protein family (RNase H2 complex component)	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
53	PTPN23	suppressor	BRO1 (PF03097, IPR004328, SM01041): BRO1-like domain Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase SOGA (PF11365, IPR027881): Protein SOGA ALIX_LYPXL_bnd (PF13949, IPR025304): ALIX V-shaped domain binding to HIV	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
54	RANBP2	oncoprotein	Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat Ran_BP1 (PF00638, IPR000156, SM00160): RanBP1 domain zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others DUF2693 (PF10902, IPR024401): Protein of unknown function (DUF2693) IR1-M (PF12185, IPR022011): Nup358/RanBP2 E3 ligase domain Dmrt1 (PF12374, IPR022114): Double-sex mab3 related transcription factor 1 TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat TPR_11 (PF13414, IPR011990): TPR repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
55	RET	parental protein	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Cadherin (PF00028, IPR002126, SM00112): Cadherin domain	AB795249, AB795250, AB795251, AB795252, AB795253, AB795254, AB795255, AB795256, AB795257, HW088349, HW088350, HW088351, HW088352
56	RNF168	interactor	ATP-synt_E (PF05680, IPR008386): ATP synthase E chain DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407) Prok-RING_4 (PF14447): Prokaryotic RING finger family 4	AB795249, AB795250, HW088349
57	SFN	suppressor	14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
58	SGF29	interactor	DUF1325 (PF07039, IPR010750): SGF29 tudor-like domain Filament (PF00038, IPR001664): Intermediate filament protein	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
59	SIRT7	interactor	DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563) SIR2 (PF02146, IPR003000): Sir2 family	AB795249, AB795250, HW088349
60	SLC38A10	interactor	Aa_trans (PF01490, IPR004758): Transmembrane amino acid transporter protein DUF2304 (PF10066, IPR019277): Uncharacterized conserved protein (DUF2304)	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
61	SNAP23	interactor	DivIC (PF04977, IPR007060): Septum formation initiator DUF16 (PF01519, IPR002862): Protein of unknown function DUF16 SNAP-25 (PF00835, IPR000928): SNAP-25 family DUF5089 (PF17002, IPR031547): Domain of unknown function (DUF5089)	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
62	SNAP25	interactor	SNAP-25 (PF00835, IPR000928): SNAP-25 family Use1 (PF09753, IPR019150): Membrane fusion protein Use1	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
63	SPG20	interactor	MIT (PF04212, IPR007330, SM00745): MIT (microtubule interacting and transport) domain Senescence (PF06911, IPR009686): Senescence-associated protein	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
64	SQSTM1	oncoprotein	PB1 (PF00564, IPR000270, SM00666): PB1 domain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type UBA_5 (PF16577, IPR015940): UBA domain	AB795249, AB795250, HW088349
65	SRP68	interactor	RhlB (PF12300, IPR022077): ATP-dependent RNA helicase RhlB SRP68 (PF16969, IPR026258): RNA-binding signal recognition particle 68	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
66	STAU1	interactor	dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif Staufen_C (PF16482, IPR032478): Staufen C-terminal domain	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
67	SYNE4	interactor	KASH (PF10541, IPR012315): Nuclear envelope localisation domain	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
68	TRAK1	interactor	HAP1_N (PF04849, IPR006933): HAP1 N-terminal conserved region Spc24 (PF08286, IPR013252): Spc24 subunit of Ndc80 Milton (PF12448, IPR022154): Kinesin associated protein	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
69	TRAK2	interactor	ZapB (PF06005, IPR009252): Cell division protein ZapB HAP1_N (PF04849, IPR006933): HAP1 N-terminal conserved region Milton (PF12448, IPR022154): Kinesin associated protein	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
70	TRIM25	interactor	Fes1 (PF08609, IPR013918): Nucleotide exchange factor Fes1 Pox_Rif (PF03340, IPR005008): Poxvirus rifampicin resistance protein SPRY (PF00622, IPR003877, SM00449): SPRY domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger Prok-RING_4 (PF14447): Prokaryotic RING finger family 4	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
71	TRIP6	interactor	DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region LIM (PF00412, IPR001781, SM00132): LIM domain	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
72	TWF1	interactor	Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
73	USPL1	interactor	zinc_ribbon_2 (PF13240, IPR026870): zinc-ribbon domain Peptidase_C98 (PF15499, IPR028890): Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF4650 (PF15509, IPR029388): Domain of unknown function (DUF4650)	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
74	VDAC1	interactor	Porin_3 (PF01459, IPR027246): Eukaryotic porin	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
75	VPS52	interactor	Vps52 (PF04129, IPR007258): Vps52 / Sac2 family COG5 (PF10392, IPR019465): Golgi transport complex subunit 5 Sec3_C (PF09763, IPR019160): Exocyst complex component Sec3	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
76	XPR1	interactor	EXS (PF03124, IPR004342): EXS family SPX (PF03105, IPR004331): SPX domain	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
77	YWHAB	interactor	14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein Virulence_fact (PF13769, IPR025989): Virulence factor	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
78	YWHAE	oncoprotein	14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
79	YWHAG	interactor	14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
80	YWHAH	interactor	14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
81	YWHAQ	interactor	14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350
82	YWHAZ	interactor	14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein	AB795249, AB795250, AB795251, AB795252, HW088349, HW088350

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