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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins SFT2D2, HERPUD2 (from a repository: Wed Aug 14 23:22:08 2019)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)9
The number (and %) of the onco-proteins1 (11.11 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)11 (30.56 %)
The number (and %) of affected PPIs7 (63.64 %)
The number of possible different fusions1
PPI diameter5
PPI radius3
The average degree of PPI1.778
Assortativity coefficient-0.4667
The network average Clustering coefficient0.000
The number (and %) of a zero Clustering coefficients9 (100.00 %)
The number (and %) of a zero Betweenness Centrality5 (55.56 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: SFT2D2,HERPUD2 All fusions
Proteins found in more fusions

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 SFT2D2parental protein2014.000Got1 (PF04178, IPR007305): Got1/Sft2-like family
2 HERPUD2parental protein5044.000Hamartin (PF04388, IPR007483): Hamartin protein
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
3 AICDAinteractor200APOBEC_N (PF08210, IPR013158): APOBEC-like N-terminal domain
4 CREB3interactor200bZIP_1 (PF00170, IPR004827): bZIP transcription factor
GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor
5 ELAVL1oncoprotein3030.000RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
6 GATAD1interactor100GATA (PF00320, IPR000679, SM00401): GATA zinc finger
7 GOLT1Binteractor2024.000Got1 (PF04178, IPR007305): Got1/Sft2-like family
8 NEDD1interactor100NRBF2 (PF08961, IPR015056): Nuclear receptor-binding factor 2, autophagy regulator
eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A
FliM (PF02154, IPR001689): Flagellar motor switch protein FliM
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Mto2_bdg (PF12808, IPR024545): Micro-tubular organiser Mto1 C-term Mto2-binding region
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
9 RNASEH2Binteractor100RNase_H2-Ydr279 (PF09468, IPR019024): Ydr279p protein family (RNase H2 complex component)

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