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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)110
The number (and %) of the onco-proteins30 (27.27 %)
The number (and %) of the tumor suppressors18 (16.36 %)
Total number of binary PPIs (saturation %)1741 (29.04 %)
The number (and %) of affected PPIs109 (6.26 %)
The number of possible different fusions27
PPI diameter4
PPI radius2
The average degree of PPI30.964
Assortativity coefficient0.1473
The network average Clustering coefficient0.645
The number (and %) of a zero Clustering coefficients2 (1.82 %)
The number (and %) of a zero Betweenness Centrality7 (6.36 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: RPS27A,IFNAR1 All fusions
Proteins found in more fusions TRIM25 (see 2 fusions); GRB2 (see 1 fusions); PARK2 (see 1 fusions); RPLP0/RPLP0P6 (see 10 fusions); EWSR1 (see 1 fusions); GAN (see 1 fusions); PIK3R1 (see 1 fusions); RPL37A/RPS24 (see 1 fusions); VCL (see 2 fusions); RACK1/FN1 (see 1 fusions); STRAP (see 1 fusions); TP53 (see 3 fusions); THAP7 (see 1 fusions); AP2M1 (see 4 fusions); APP (see 5 fusions); RNF11 (see 1 fusions); RPS24/RPS23 (see 1 fusions); SMAD2 (see 2 fusions); RPL5 (see 1 fusions); ERBB3 (see 2 fusions); STAT3 (see 2 fusions); MCM2 (see 1 fusions); RACK1 (see 3 fusions); DAZAP2 (see 2 fusions); FN1/RPL6 (see 1 fusions); ERRFI1 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 RPS27Aparental protein960.3353005.009DUF1049 (PF06305, IPR010445): Protein of unknown function (DUF1049)
2 IFNAR1parental protein130.115423.798Interfer-bind (PF09294, IPR015373): Interferon-alpha/beta receptor, fibronectin type III
Tissue_fac (PF01108, IPR003961): Tissue factor
3 AP2M1protein found in more fusions120.345125.833Adap_comp_sub (PF00928, IPR008968): Adaptor complexes medium subunit family
Clat_adaptor_s (PF01217, IPR022775): Clathrin adaptor complex small chain
4 APPprotein found in more fusions230.42986.120APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding
Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP)
BUD22 (PF09073, IPR015158): BUD22
IncA (PF04156, IPR007285): IncA protein
Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus
APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
5 ARRB1interactor140.6268.415Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain
Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain
6 ARRB2interactor320.532100.944Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain
Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain
7 BLMsuppressor70.7334.319BDHCT (PF08072, IPR012532): BDHCT (NUC031) domain
DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
HRDC (PF00570, IPR002121, SM00341): HRDC domain
RQC (PF09382, IPR018982, SM00956): RQC domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
ALMT (PF11744, IPR020966): Aluminium activated malate transporter
RecQ_Zn_bind (PF16124, IPR032284): RecQ zinc-binding
BLM_N (PF16202, IPR032437): N-terminal region of Bloom syndrome protein
BDHCT_assoc (PF16204, IPR032439): BDHCT-box associated domain on Bloom syndrome protein
8 BTRConcoprotein70.40025.933WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
F-box-like (PF12937, IPR001810): F-box-like
9 CALCOCO2interactor60.4004.796bZIP_1 (PF00170, IPR004827): bZIP transcription factor
CALCOCO1 (PF07888, IPR012852): Calcium binding and coiled-coil domain (CALCOCO1) like
DUF641 (PF04859, IPR006943): Plant protein of unknown function (DUF641)
OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding
zf-C2H2_4 (PF13894): C2H2-type zinc finger
10 CDK11Boncoprotein31.0000DDHD (PF02862, IPR004177, SM01127): DDHD domain
DivIC (PF04977, IPR007060): Septum formation initiator
Pkinase (PF00069, IPR000719): Protein kinase domain
DUF4748 (PF15932, IPR031833): Domain of unknown function (DUF4748)
11 CDK2suppressor380.680107.734Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family
Pkinase (PF00069, IPR000719): Protein kinase domain
12 CRY1interactor60.40010.381DNA_photolyase (PF00875, IPR006050): DNA photolyase
FAD_binding_7 (PF03441, IPR005101): FAD binding domain of DNA photolyase
13 CTSGinteractor21.0000Trypsin (PF00089, IPR001254, SM00020): Trypsin
14 DAZAP2protein found in more fusions60.30040.515DAZAP2 (PF11029, IPR022730): DAZ associated protein 2 (DAZAP2)
15 EEDsuppressor270.76911.585WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
16 ERBB3oncoprotein80.38155.248Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
17 ERRFI1suppressor51.0000GTPase_binding (PF09027, IPR015116): GTPase binding
Inhibitor_Mig-6 (PF11555, IPR021619): EGFR receptor inhibitor Mig-6
18 ESRRBsuppressor90.55611.060zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
19 EWSR1oncoprotein210.53744.095RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
Keratin_2_head (PF16208, IPR032444): Keratin type II head
20 FBXO25suppressor50.5002.574Elongin_A (PF06881, IPR010684): RNA polymerase II transcription factor SIII (Elongin) subunit A
21 FBXW11interactor110.40056.391WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
F-box-like (PF12937, IPR001810): F-box-like
22 FN1oncoprotein520.636209.336fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain
fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
23 GANprotein found in more fusions170.8089.991BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
Kelch_3 (PF13415): Galactose oxidase, central domain
Kelch_5 (PF13854): Kelch motif
24 GRB2oncoprotein160.390177.945SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
DUF5093 (PF17011, IPR031533): Domain of unknown function (DUF5093)
25 HIST1H3Einteractor150.7246.161Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
26 HNRNPA1interactor290.405109.396RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1
27 HNRNPA2B1oncoprotein210.34384.107RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
28 IFNAR2interactor40.66732.112Interfer-bind (PF09294, IPR015373): Interferon-alpha/beta receptor, fibronectin type III
Tissue_fac (PF01108, IPR003961): Tissue factor
29 ISG15suppressor70.23813.915ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
30 ITGA4interactor470.625134.834FG-GAP (PF01839, IPR013517): FG-GAP repeat
Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region
Integrin_alpha2 (PF08441, IPR013649): Integrin alpha
31 MCM2oncoprotein560.565300.731AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA)
MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
32 MCM5oncoprotein100.6673.507MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
33 MDM2oncoprotein210.48469.607Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region
Presenilin (PF01080, IPR001108): Presenilin
SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain
zf-FPG_IleRS (PF06827, IPR010663): Zinc finger found in FPG and IleRS
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
34 NSUN2interactor50.7000.286Methyltr_RsmB-F (PF01189, IPR001678): 16S rRNA methyltransferase RsmB/F
35 PAN2interactor420.90714.208RNase_T (PF00929, IPR013520): Exonuclease
UCH_1 (PF13423, IPR001394): Ubiquitin carboxyl-terminal hydrolase
WD40_like (PF17005, IPR031544): WD40-like domain
36 PARK2suppressor220.50052.625IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
37 PAXIP1interactor60.33315.453BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
IPT (PF01745, IPR002648, SM00429): Isopentenyl transferase
SURF6 (PF04935, IPR007019): Surfeit locus protein 6
DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052)
CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance
PTCB-BRCT (PF12738, IPR001357): twin BRCT domain
BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain
LIG3_BRCT (PF16759, IPR031916): DNA ligase 3 BRCT domain
RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain
38 PHGDHinteractor80.5007.2752-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
39 PIK3R1oncoprotein60.40023.110RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_2 (PF07653, IPR011511): Variant SH3 domain
PI3K_P85_iSH2 (PF16454, IPR032498): Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain
40 PRKD2interactor100ABC1 (PF03109, IPR004147): ABC1 family
Pkinase (PF00069, IPR000719): Protein kinase domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
41 PRMT1interactor100.36149.364Methyltransf_25 (PF13649): Methyltransferase domain
42 PTENsuppressor150.86734.205DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain
PTEN_C2 (PF10409, IPR014020): C2 domain of PTEN tumour-suppressor protein
43 PTGES3interactor110.7111.425CS (PF04969, IPR007052): CS domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
44 RACK1suppressor330.548631.517WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
45 RAD21oncoprotein270.72938.079Rad21_Rec8 (PF04824, IPR006909): Conserved region of Rad21 / Rec8 like protein
Rad21_Rec8_N (PF04825, IPR006910): N terminus of Rad21 / Rec8 like protein
FAM176 (PF14851): FAM176 family
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
46 RHOAsuppressor50.3005.595Ras (PF00071, IPR001806, SM00173): Ras family
47 RNF11protein found in more fusions60.4005.708zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
zf-ANAPC11 (PF12861, IPR024991): Anaphase-promoting complex subunit 11 RING-H2 finger
48 RPL10suppressor520.84282.393Ribosomal_L16 (PF00252, IPR016180): Ribosomal protein L16p/L10e
49 RPL10Ainteractor530.86721.045Ribosomal_L1 (PF00687, IPR028364): Ribosomal protein L1p/L10e family
50 RPL10Linteractor440.9643.150Ribosomal_L16 (PF00252, IPR016180): Ribosomal protein L16p/L10e
Cytochrome_P460 (PF16694, IPR032033): Cytochrome P460
51 RPL11suppressor570.789216.638Ribosomal_L5 (PF00281, IPR002132): Ribosomal protein L5
Ribosomal_L5_C (PF00673, IPR002132): ribosomal L5P family C-terminus
52 RPL14interactor570.76973.382KOW (PF00467, IPR005824, SM00739): KOW motif
Ribosomal_L14e (PF01929, IPR002784): Ribosomal protein L14
UPF0688 (PF15772, IPR031530): UPF0688 family
53 RPL15interactor520.86334.481Ribosomal_L15e (PF00827, IPR000439): Ribosomal L15
54 RPL17interactor500.86019.055Ribosomal_L22 (PF00237, IPR001063): Ribosomal protein L22p/L17e
55 RPL18interactor560.80575.199Ribosomal_L18 (PF17135): Ribosomal protein 60S L18 and 50S L18e
56 RPL18Ainteractor510.85748.511Ribosomal_L18A (PF01775, IPR023573): Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A
57 RPL19interactor510.85439.904DUF1682 (PF07946, IPR012879): Protein of unknown function (DUF1682)
Ribosomal_L19e (PF01280, IPR000196): Ribosomal protein L19e
58 RPL21interactor530.85138.903Ribosomal_L21e (PF01157, IPR001147): Ribosomal protein L21e
59 RPL22oncoprotein550.79858.160Ribosomal_L22e (PF01776, IPR002671): Ribosomal L22e protein family
60 RPL23interactor580.761115.429Ribosomal_L14 (PF00238, IPR000218): Ribosomal protein L14p/L23e
61 RPL23Ainteractor560.79755.303Ribosomal_L23 (PF00276, IPR013025): Ribosomal protein L23
Ribosomal_L23eN (PF03939, IPR005633): Ribosomal protein L23, N-terminal domain
62 RPL24interactor550.79298.714MAS20 (PF02064, IPR002056): MAS20 protein import receptor
Ribosomal_L24e (PF01246, IPR000988): Ribosomal protein L24e
63 RPL31interactor550.80340.820Ribosomal_L31e (PF01198, IPR000054): Ribosomal protein L31e
64 RPL37Aprotein found in more fusions510.86434.336Ribosomal_L37ae (PF01780, IPR002674): Ribosomal L37ae protein family
65 RPL4interactor560.77777.733Ribosomal_L4 (PF00573, IPR002136): Ribosomal protein L4/L1 family
Ribos_L4_asso_C (PF14374, IPR025755): 60S ribosomal protein L4 C-terminal domain
66 RPL5suppressor560.82167.194Ribosomal_L18_c (PF14204, IPR025607): Ribosomal L18 C-terminal region
Ribosomal_L5e (PF17144): Ribosomal large subunit proteins 60S L5, and 50S L18
67 RPL6protein found in more fusions540.81339.116Ribosomal_L6e (PF01159, IPR000915): Ribosomal protein L6e
Ribosomal_L6e_N (PF03868, IPR005568): Ribosomal protein L6, N-terminal domain
68 RPL7Ainteractor570.78463.434Ribosomal_L7Ae (PF01248, IPR004038): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
69 RPL9interactor510.88854.851Ribosomal_L6 (PF00347, IPR020040): Ribosomal protein L6
70 RPLP0protein found in more fusions570.79352.721Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
Ribosomal_L10 (PF00466, IPR001790): Ribosomal protein L10
71 RPLP0P6protein found in more fusions470.89024.576NA
72 RPLP1interactor420.9712.083Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
73 RPS10interactor590.717208.771S10_plectin (PF03501, IPR005326): Plectin/S10 domain
74 RPS10P5interactor201.0000DUF11 (PF01345, IPR001434): Domain of unknown function DUF11
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase (PF00069, IPR000719): Protein kinase domain
PPAK (PF02818, IPR004168): PPAK motif
Titin_Z (PF09042, IPR015129): Titin Z
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Y_Y_Y (PF07495, IPR011123): Y_Y_Y domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
Ig_3 (PF13927): Immunoglobulin domain
75 RPS11interactor540.84721.093Ribosomal_S17 (PF00366, IPR000266): Ribosomal protein S17
Ribosomal_S17_N (PF16205, IPR032440): Ribosomal_S17 N-terminal
76 RPS12interactor510.87227.422Ribosomal_L7Ae (PF01248, IPR004038): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
77 RPS13interactor540.82737.712Ribosomal_S13_N (PF08069, IPR012606): Ribosomal S13/S15 N-terminal domain
Ribosomal_S15 (PF00312, IPR000589): Ribosomal protein S15
78 RPS15Ainteractor540.83826.598Ribosomal_S8 (PF00410, IPR000630): Ribosomal protein S8
79 RPS16interactor580.77773.713Ribosomal_S9 (PF00380, IPR000754): Ribosomal protein S9/S16
80 RPS19interactor600.728113.421Ribosomal_S19e (PF01090, IPR001266): Ribosomal protein S19e
81 RPS2interactor580.75089.054Ribosomal_S5 (PF00333, IPR013810): Ribosomal protein S5, N-terminal domain
Ribosomal_S5_C (PF03719, IPR005324): Ribosomal protein S5, C-terminal domain
82 RPS23protein found in more fusions500.88614.633Ribosom_S12_S23 (PF00164, IPR006032): Ribosomal protein S12/S23
83 RPS24protein found in more fusions520.88514.076Fascin (PF06268, IPR022768): Fascin domain
Ribosomal_S24e (PF01282, IPR001976): Ribosomal protein S24e
DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457)
84 RPS26interactor540.81439.587Ribosomal_S26e (PF01283, IPR000892): Ribosomal protein S26e
85 RPS3interactor630.693151.784KH_2 (PF07650, IPR004044): KH domain
Ribosomal_S3_C (PF00189, IPR001351): Ribosomal protein S3, C-terminal domain
86 RPS3Ainteractor580.77196.938Ribosomal_S3Ae (PF01015, IPR001593): Ribosomal S3Ae family
87 RPS4Xinteractor580.78344.117KOW (PF00467, IPR005824, SM00739): KOW motif
Ribosomal_S4e (PF00900, IPR013845): Ribosomal family S4e
RS4NT (PF08071, IPR013843): RS4NT (NUC023) domain
S4 (PF01479, IPR002942, SM00363): S4 domain
40S_S4_C (PF16121, IPR032277): 40S ribosomal protein S4 C-terminus
88 RPS5interactor550.82437.573Ribosomal_S7 (PF00177, IPR023798): Ribosomal protein S7p/S5e
89 RPS6interactor570.77161.198Ribosomal_S6e (PF01092, IPR001377): Ribosomal protein S6e
DUF4574 (PF15141, IPR027896): Domain of unknown function (DUF4574)
90 RPS8interactor600.738110.918Ribosomal_S8e (PF01201, IPR022309): Ribosomal protein S8e
91 RPSAinteractor530.82460.338Ribosomal_S2 (PF00318, IPR001865): Ribosomal protein S2
40S_SA_C (PF16122, IPR032281): 40S ribosomal protein SA C-terminus
92 SMAD2suppressor80.38110.953MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
93 SOCS1suppressor60.26743.623SH2 (PF00017, IPR000980, SM00252): SH2 domain
SOCS_box (PF07525, IPR001496): SOCS box
94 STAT2oncoprotein30.6672.187SH2 (PF00017, IPR000980, SM00252): SH2 domain
STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain
STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain
STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain
STAT2_C (PF12188, IPR022756): Signal transducer and activator of transcription 2 C terminal
95 STAT3suppressor50.33325.064SH2 (PF00017, IPR000980, SM00252): SH2 domain
STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain
STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain
STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain
96 STAT6oncoprotein50.200110.654SH2 (PF00017, IPR000980, SM00252): SH2 domain
STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain
STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain
STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain
STAT6_C (PF14596, IPR028187): STAT6 C-terminal
97 STRAPprotein found in more fusions80.5246.187WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
98 TAF10interactor21.0000TFIID_30kDa (PF03540, IPR003923): Transcription initiation factor TFIID 23-30kDa subunit
99 TARSinteractor90.5284.154HGTP_anticodon (PF03129, IPR004154): Anticodon binding domain
TGS (PF02824, IPR004095): TGS domain
tRNA-synt_2b (PF00587, IPR002314): tRNA synthetase class II core domain (G, H, P, S and T)
tRNA_SAD (PF07973, IPR012947, SM00863): Threonyl and Alanyl tRNA synthetase second additional domain
100 THAP7protein found in more fusions50.6670.276THAP (PF05485, IPR006612, SM00980): THAP domain
Tho2 (PF11262, IPR021418): Transcription factor/nuclear export subunit protein 2
101 TP53suppressor490.539627.644DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
P53 (PF00870, IPR011615): P53 DNA-binding domain
P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
102 TRIM25protein found in more fusions40.6670.352Fes1 (PF08609, IPR013918): Nucleotide exchange factor Fes1
Pox_Rif (PF03340, IPR005008): Poxvirus rifampicin resistance protein
SPRY (PF00622, IPR003877, SM00449): SPRY domain
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
PRY (PF13765, IPR006574, SM00589): SPRY-associated domain
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
103 TUBA4Ainteractor90.27860.447Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
104 TYK2interactor50.33312.868Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
105 UBA52interactor240.48982.537Ribosomal_L40e (PF01020, IPR001975): Ribosomal L40e family
VWC (PF00093, IPR001007, SM00214): von Willebrand factor type C domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
106 UBASH3Binteractor90.46413.753His_Phos_1 (PF00300, IPR013078, SM00855): Histidine phosphatase superfamily (branch 1)
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
2_5_RNA_ligase2 (PF13563): 2'-5' RNA ligase superfamily
SH3_9 (PF14604, IPR001452): Variant SH3 domain
107 UBL4Ainteractor430.86627.398ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
108 VCAM1interactor450.628158.142C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
109 VCLoncoprotein70.6670.440Vinculin (PF01044, IPR006077): Vinculin family
110 ZNF512Binteractor100YTV (PF07639, IPR011521): YTV
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-C2HC5 (PF06221, IPR009349): Putative zinc finger motif, C2HC5-type
zf-Nse (PF11789, IPR004181): Zinc-finger of the MIZ type in Nse subunit
Zn_Tnp_IS1595 (PF12760, IPR024442): Transposase zinc-ribbon domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-C2H2_aberr (PF17017, IPR031514): Aberrant zinc-finger

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