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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins RBM47, APOA2 (from a repository: Mon Jul 22 16:43:24 2019)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)21
The number (and %) of the onco-proteins4 (19.05 %)
The number (and %) of the tumor suppressors1 (4.76 %)
Total number of binary PPIs (saturation %)47 (22.38 %)
The number (and %) of affected PPIs19 (40.43 %)
The number of possible different fusions2
PPI diameter5
PPI radius3
The average degree of PPI3.429
Assortativity coefficient-0.3550
The network average Clustering coefficient0.614
The number (and %) of a zero Clustering coefficients3 (14.29 %)
The number (and %) of a zero Betweenness Centrality12 (57.14 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: RBM47,APOA2 All fusions
Proteins found in more fusions APOD (see 2 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 RBM47parental protein50.20090.000Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
2 APOA2parental protein140.154190.333ApoA-II (PF04711, IPR006801): Apolipoprotein A-II (ApoA-II)
3 ABCA13interactor21.0000ABC_tran (PF00005, IPR003439): ABC transporter
ApoLp-III (PF07464, IPR010009): Apolipophorin-III precursor (apoLp-III)
DUF87 (PF01935, IPR002789): Domain of unknown function DUF87
ABC2_membrane_3 (PF12698): ABC-2 family transporter protein
AAA_21 (PF13304, IPR003959): AAA domain, putative AbiEii toxin, Type IV TA system
DUF4637 (PF15470, IPR029174): Domain of unknown function (DUF4637)
4 ALBinteractor40.500168.000Serum_albumin (PF00273, IPR014760, SM00103): Serum albumin family
5 APOA1interactor120.20091.667ApoA-II (PF04711, IPR006801): Apolipoprotein A-II (ApoA-II)
Apolipoprotein (PF01442, IPR000074): Apolipoprotein A1/A4/E domain
Gp-FAR-1 (PF05823, IPR008632): Nematode fatty acid retinoid binding protein (Gp-FAR-1)
6 APODprotein found in more fusions40.6670.667Lipocalin_2 (PF08212, IPR000566): Lipocalin-like domain
7 APOFinteractor21.0000Apolipo_F (PF15148, IPR026114): Apolipoprotein F
8 ATMsuppressor40.333150.000FAT (PF02259, IPR003151): FAT domain
FATC (PF02260, IPR003152): FATC domain
HEAT (PF02985, IPR000357): HEAT repeat
PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
TAN (PF11640, IPR021668): Telomere-length maintenance and DNA damage repair
ANAPC5 (PF12862, IPR026000): Anaphase-promoting complex subunit 5
9 C1orf94interactor200DUF4688 (PF15752, IPR031496): Domain of unknown function (DUF4688)
10 CATSPER1interactor200Ion_trans (PF00520, IPR005821): Ion transport protein
MMM1 (PF10296, IPR019411): Maintenance of mitochondrial morphology protein 1
11 CREB3interactor50.5002.667bZIP_1 (PF00170, IPR004827): bZIP transcription factor
GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor
12 DGAT1interactor31.0000MBOAT (PF03062, IPR004299): MBOAT, membrane-bound O-acyltransferase family
13 ELAVL1oncoprotein40.66716.000RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
14 GDPD1interactor31.0000GDPD (PF03009, IPR004129): Glycerophosphoryl diester phosphodiesterase family
PI-PLC-X (PF00388, IPR000909, SM00148): Phosphatidylinositol-specific phospholipase C, X domain
15 HSFY1interactor100HSF_DNA-bind (PF00447, IPR000232, SM00415): HSF-type DNA-binding
16 JUNoncoprotein31.0000bZIP_1 (PF00170, IPR004827): bZIP transcription factor
Jun (PF03957, IPR005643): Jun-like transcription factor
17 LCATinteractor21.0000LCAT (PF02450, IPR003386): Lecithin:cholesterol acyltransferase
18 PLTPinteractor21.0000LBP_BPI_CETP (PF01273, IPR017942, SM00328): LBP / BPI / CETP family, N-terminal domain
LBP_BPI_CETP_C (PF02886, IPR001124, SM00329): LBP / BPI / CETP family, C-terminal domain
19 RNF2interactor31.0000zf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
20 SCARB1oncoprotein21.0000CD36 (PF01130, IPR002159): CD36 family
21 VKORC1interactor40.6670.667VKOR (PF07884, IPR012932, SM00756): Vitamin K epoxide reductase family

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