Find Fusion Network

Enter
Fusion ID:
Protein names:


Level of PPIs:
or Upload text file:
Update repository
Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins HLA-A, SH3GL2 (from a repository: Sun Sep 1 01:34:05 2019)
Examples

Cytoscape Web will replace the contents your graph
PPI Properties:

Click on nodes
or edges

Layout Tree
Circle
Radial
Force Directed
Preset
Export graph
PDF file
SVG file
SIF file
XML file
GraphML file

Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)121
The number (and %) of the onco-proteins37 (30.58 %)
The number (and %) of the tumor suppressors9 (7.44 %)
Total number of binary PPIs (saturation %)451 (6.21 %)
The number (and %) of affected PPIs122 (27.05 %)
The number of possible different fusions27
PPI diameter4
PPI radius2
The average degree of PPI6.678
Assortativity coefficient-0.2714
The network average Clustering coefficient0.368
The number (and %) of a zero Clustering coefficients30 (24.79 %)
The number (and %) of a zero Betweenness Centrality36 (29.75 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: SH3GL2,HLA-A All fusions
Proteins found in more fusions ERBB3 (see 2 fusions); STAT3 (see 2 fusions); CD2AP (see 1 fusions); ILK (see 2 fusions); APP (see 5 fusions); HLA-B (see 4 fusions); SYVN1 (see 1 fusions); VCP (see 4 fusions); SH3KBP1 (see 1 fusions); ACTG1 (see 5 fusions); ZDHHC17 (see 2 fusions); EGFR (see 2 fusions); SH3GL2 (see 1 fusions); HLA-C (see 1 fusions); CUL7 (see 2 fusions); GNAS (see 5 fusions); ITSN1 (see 2 fusions); COPB1 (see 2 fusions); UBC (see 7 fusions); LRRK2 (see 1 fusions); B2M (see 10 fusions); COPG1 (see 1 fusions); BCAP31 (see 3 fusions); CALR (see 8 fusions); HLA-B/HLA-C (see 4 fusions); F13A1 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 SH3GL2parental protein580.0554939.502BAR (PF03114, IPR004148, SM00721): BAR domain
SH3_2 (PF07653, IPR011511): Variant SH3 domain
2 HLA-Aparental protein640.0635745.168DUF202 (PF02656, IPR003807): Domain of unknown function (DUF202)
MHC_I (PF00129, IPR001039): Class I Histocompatibility antigen, domains alpha 1 and 2
MHC_I_C (PF06623, IPR010579): MHC_I C-terminus
C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
3 ACTG1protein found in more fusions70.067126.920Actin (PF00022, IPR004000, SM00268): Actin
4 ADAM15interactor100CD20 (PF04103, IPR007237): CD20-like family
Pep_M12B_propep (PF01562, IPR002870): Reprolysin family propeptide
Reprolysin (PF01421, IPR001590): Reprolysin (M12B) family zinc metalloprotease
ADAM_CR (PF08516, IPR006586, SM00608): ADAM cysteine-rich
Disintegrin (PF00200, IPR001762, SM00050): Disintegrin
5 ADAM19interactor2025.508Adeno_E3_CR2 (PF02439, IPR003470): Adenovirus E3 region protein CR2
EGF_2 (PF07974, IPR013111): EGF-like domain
Pep_M12B_propep (PF01562, IPR002870): Reprolysin family propeptide
Reprolysin (PF01421, IPR001590): Reprolysin (M12B) family zinc metalloprotease
ADAM_CR (PF08516, IPR006586, SM00608): ADAM cysteine-rich
Disintegrin (PF00200, IPR001762, SM00050): Disintegrin
6 ADAM9oncoprotein2071.292EB (PF01683, IPR006149): EB module
Pep_M12B_propep (PF01562, IPR002870): Reprolysin family propeptide
Reprolysin (PF01421, IPR001590): Reprolysin (M12B) family zinc metalloprotease
ADAM_CR (PF08516, IPR006586, SM00608): ADAM cysteine-rich
Disintegrin (PF00200, IPR001762, SM00050): Disintegrin
7 AMPHoncoprotein90.33360.997BAR (PF03114, IPR004148, SM00721): BAR domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
PBP_N (PF17093, IPR031375): Penicillin-binding protein N-terminus
8 APPprotein found in more fusions270.0891205.047APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding
Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP)
BUD22 (PF09073, IPR015158): BUD22
IncA (PF04156, IPR007285): IncA protein
Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus
APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
9 ARHGAP8interactor31.0000RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
CRAL_TRIO (PF00650, IPR001251, SM00516): CRAL/TRIO domain
CRAL_TRIO_2 (PF13716, IPR001251): Divergent CRAL/TRIO domain
10 ARNT2interactor40.33370.321HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
PAS (PF00989, IPR013767, SM00091): PAS fold
PAS_3 (PF08447, IPR013655): PAS fold
PAP2 (PF01569, IPR000326, SM00014): PAP2 superfamily
11 ATMsuppressor40.33378.057FAT (PF02259, IPR003151): FAT domain
FATC (PF02260, IPR003152): FATC domain
HEAT (PF02985, IPR000357): HEAT repeat
PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
TAN (PF11640, IPR021668): Telomere-length maintenance and DNA damage repair
ANAPC5 (PF12862, IPR026000): Anaphase-promoting complex subunit 5
12 ATP1B4interactor100Gcd10p (PF04189, IPR007316): Gcd10p family
Na_K-ATPase (PF00287, IPR000402): Sodium / potassium ATPase beta chain
13 ATXN2interactor60.53358.838LsmAD (PF06741, IPR009604): LsmAD domain
PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region
DUF3446 (PF11928, IPR021849): Domain of unknown function (DUF3446)
Spt20 (PF12090, IPR021950): Spt20 family
SM-ATX (PF14438, IPR025852): Ataxin 2 SM domain
14 ATXN3interactor80.38175.960Josephin (PF02099, IPR006155): Josephin
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
15 AZU1interactor30.33319.224Trypsin (PF00089, IPR001254, SM00020): Trypsin
16 B2Moncoprotein120.40043.937C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
17 BAG6interactor110.33370.962DUF1179 (PF06678, IPR009564): Protein of unknown function (DUF1179)
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
DUF2939 (PF11159, IPR021330): Protein of unknown function (DUF2939)
DUF3538 (PF12057, IPR021925): Domain of unknown function (DUF3538)
PRIMA1 (PF16101): Proline-rich membrane anchor 1
18 BCAP31protein found in more fusions100.36173.947Bap31 (PF05529, IPR008417): B-cell receptor-associated protein 31-like
DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948)
19 CALRoncoprotein120.309261.154Calreticulin (PF00262, IPR001580): Calreticulin family
DDHD (PF02862, IPR004177, SM01127): DDHD domain
20 CBLsuppressor130.379133.273Cbl_N (PF02262, IPR003153): CBL proto-oncogene N-terminal domain 1
Cbl_N2 (PF02761, IPR014741): CBL proto-oncogene N-terminus, EF hand-like domain
Cbl_N3 (PF02762, IPR014742): CBL proto-oncogene N-terminus, SH2-like domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain
21 CCDC8interactor170.208230.128Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
PNMA (PF14893, IPR026523): PNMA
22 CD1Binteractor30.33385.114C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
MLANA (PF14991, IPR029242): Protein melan-A
MHC_I_3 (PF16497, IPR011161): MHC-I family domain
23 CD2APprotein found in more fusions90.57140.068SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
betaPIX_CC (PF16523, IPR032409): betaPIX coiled coil
24 CD3Einteractor100ITAM (PF02189, IPR003110, SM00077): Immunoreceptor tyrosine-based activation motif
P5-ATPase (PF12409, IPR006544): P5-type ATPase cation transporter
Ig_5 (PF16681): Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain
25 CD8Ainteractor41.0000V-set (PF07686, IPR013106): Immunoglobulin V-set domain
26 CLEC3Binteractor21.0000Chordopox_A33R (PF05966, IPR009238): Chordopoxvirus A33R protein
Ribosomal_L29 (PF00831, IPR001854): Ribosomal L29 protein
Lectin_C (PF00059, IPR001304, SM00034): Lectin C-type domain
27 COPB1protein found in more fusions120.345191.939Adaptin_N (PF01602, IPR002553): Adaptin N terminal region
Coatamer_beta_C (PF07718, IPR011710): Coatomer beta C-terminal region
Coatomer_b_Cpla (PF14806, IPR029446): Coatomer beta subunit appendage platform
28 COPG1protein found in more fusions90.39328.631Adaptin_N (PF01602, IPR002553): Adaptin N terminal region
COP-gamma_platf (PF08752, IPR013040): Coatomer gamma subunit appendage platform subdomain
Coatomer_g_Cpla (PF16381, IPR032154): Coatomer subunit gamma-1 C-terminal appendage platform
29 CUL7protein found in more fusions110.40067.211ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10)
Cullin (PF00888, IPR001373, SM00182): Cullin family
DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918)
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7
30 DACT1suppressor100Dapper (PF15268, IPR024843): Dapper
31 DERL1interactor110.400123.371DER1 (PF04511, IPR007599): Der1-like family
32 DLGAP4interactor205.296GKAP (PF03359, IPR005026): Guanylate-kinase-associated protein (GKAP) protein
33 DNM1interactor100.44433.373Dynamin_M (PF01031, IPR000375): Dynamin central region
GED (PF02212, IPR003130, SM00302): Dynamin GTPase effector domain
PH (PF00169, IPR001849, SM00233): PH domain
Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family
34 DNM2interactor120.333149.575Dynamin_M (PF01031, IPR000375): Dynamin central region
GED (PF02212, IPR003130, SM00302): Dynamin GTPase effector domain
PH (PF00169, IPR001849, SM00233): PH domain
Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family
35 DNM3interactor50.40042.607Dynamin_M (PF01031, IPR000375): Dynamin central region
GED (PF02212, IPR003130, SM00302): Dynamin GTPase effector domain
PH (PF00169, IPR001849, SM00233): PH domain
Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family
36 DPPA4interactor60.50044.366Ribosomal_L40e (PF01020, IPR001975): Ribosomal L40e family
DCR (PF14047, IPR025891): Dppa2/4 conserved region
Dppa2_A (PF14049, IPR025892): Dppa2/4 conserved region in higher vertebrates
37 DPYSL4interactor40.50011.512Amidohydro_1 (PF01979, IPR006680): Amidohydrolase family
Amidohydro_3 (PF07969, IPR013108): Amidohydrolase family
38 DYRK1Aoncoprotein70.33343.512DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755)
Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region
Pkinase (PF00069, IPR000719): Protein kinase domain
FAM199X (PF15814, IPR029672): Protein family FAM199X
39 EGFL6oncoprotein21.0000C_tripleX (PF02363, IPR003341): Cysteine rich repeat
EGF_2 (PF07974, IPR013111): EGF-like domain
EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain
MAM (PF00629, IPR000998, SM00137): MAM domain, meprin/A5/mu
hEGF (PF12661, IPR013032): Human growth factor-like EGF
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site
40 EGFRoncoprotein280.1991374.662Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT)
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
41 EMDinteractor130.197337.259LEM (PF03020, IPR003887, SM00540): LEM domain
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
42 ERBB3oncoprotein80.238155.656Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
43 ERHinteractor40.50040.658ER (PF01133, IPR000781): Enhancer of rudimentary
44 F13A1protein found in more fusions200Transglut_C (PF00927, IPR008958): Transglutaminase family, C-terminal ig like domain
Transglut_N (PF00868, IPR001102): Transglutaminase family
Transglut_core (PF01841, IPR002931, SM00460): Transglutaminase-like superfamily
45 GABREinteractor100Neur_chan_LBD (PF02931, IPR006202): Neurotransmitter-gated ion-channel ligand binding domain
Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
46 GCH1interactor200GTP_cyclohydroI (PF01227, IPR020602): GTP cyclohydrolase I
47 GNASoncoprotein60.6004.595G-alpha (PF00503, IPR001019, SM00275): G-protein alpha subunit
48 GSTM3interactor200GST_C (PF00043, IPR004046): Glutathione S-transferase, C-terminal domain
GST_N (PF02798, IPR004045): Glutathione S-transferase, N-terminal domain
49 HERC2interactor90.286101.440ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10)
Cyt-b5 (PF00173, IPR001199, SM01117): Cytochrome b5-like Heme/Steroid binding domain
MIB_HERC2 (PF06701, IPR010606): Mib_herc2
RCC1 (PF00415, IPR000408): Regulator of chromosome condensation (RCC1) repeat
zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box)
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7
Med3 (PF11593, IPR020998): Mediator complex subunit 3 fungal
RCC1_2 (PF13540): Regulator of chromosome condensation (RCC1) repeat
50 HLA-Boncoprotein100.41724.660MHC_I (PF00129, IPR001039): Class I Histocompatibility antigen, domains alpha 1 and 2
MHC_I_C (PF06623, IPR010579): MHC_I C-terminus
C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
51 HLA-Cprotein found in more fusions140.29589.668Marek_A (PF02124, IPR001038): Marek's disease glycoprotein A
MHC_I (PF00129, IPR001039): Class I Histocompatibility antigen, domains alpha 1 and 2
MHC_I_C (PF06623, IPR010579): MHC_I C-terminus
C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
52 HLA-DPA1interactor21.0000MHC_II_alpha (PF00993, IPR001003, SM00920): Class II histocompatibility antigen, alpha domain
C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
C1-set_C (PF16196, IPR032431): C1-set C-terminal domain
53 HLA-DQA1interactor20262.445MHC_II_alpha (PF00993, IPR001003, SM00920): Class II histocompatibility antigen, alpha domain
C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
C1-set_C (PF16196, IPR032431): C1-set C-terminal domain
54 HLA-DRB5interactor100MHC_II_beta (PF00969, IPR000353, SM00921): Class II histocompatibility antigen, beta domain
C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
55 HLA-Einteractor70.57110.330MHC_I (PF00129, IPR001039): Class I Histocompatibility antigen, domains alpha 1 and 2
MHC_I_C (PF06623, IPR010579): MHC_I C-terminus
C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
AA_permease_C (PF13906, IPR029485): C-terminus of AA_permease
56 HS2ST1interactor100Sulfotransfer_2 (PF03567, IPR005331): Sulfotransferase family
DICT (PF10069, IPR019278): Sensory domain in DIguanylate Cyclases and Two-component system
57 IFI16suppressor40.16742.776HIN (PF02760, IPR004021): HIN-200/IF120x domain
PYRIN (PF02758, IPR004020): PAAD/DAPIN/Pyrin domain
Mitofilin (PF09731, IPR019133): Mitochondrial inner membrane protein
58 IGHMinteractor30.66729.548C2-set_2 (PF08205, IPR013162): CD80-like C2-set immunoglobulin domain
C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
59 IL20RBinteractor100Interfer-bind (PF09294, IPR015373): Interferon-alpha/beta receptor, fibronectin type III
Tissue_fac (PF01108, IPR003961): Tissue factor
60 IL6oncoprotein100IL6 (PF00489, IPR003573, SM00126): Interleukin-6/G-CSF/MGF family
61 ILKsuppressor70.20082.789Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
62 IPO11interactor30.6676.389DUF1539 (PF07560, IPR011436): Domain of Unknown Function (DUF1539)
HEAT (PF02985, IPR000357): HEAT repeat
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
HEAT_2 (PF13646): HEAT repeats
63 IRAK1interactor60.40013.237Death (PF00531, IPR000488, SM00005): Death domain
Pkinase (PF00069, IPR000719): Protein kinase domain
64 ITCHinteractor100.36183.932C2 (PF00168, IPR000008, SM00239): C2 domain
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
65 ITM2Binteractor21.0000BRICHOS (PF04089, IPR007084, SM01039): BRICHOS domain
SpoVG (PF04026, IPR007170): SpoVG
66 ITSN1protein found in more fusions100.52813.387C2 (PF00168, IPR000008, SM00239): C2 domain
VIT1 (PF01988, IPR008217): VIT family
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
FmdE (PF02663, IPR003814): FmdE, Molybdenum formylmethanofuran dehydrogenase operon
GSH_synthase (PF03199, IPR004887): Eukaryotic glutathione synthase
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand
DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915)
SH3_9 (PF14604, IPR001452): Variant SH3 domain
DUF4748 (PF15932, IPR031833): Domain of unknown function (DUF4748)
INTAP (PF16617): Intersectin and clathrin adaptor AP2 binding region
PH_13 (PF16652, IPR001849): Pleckstrin homology domain
67 KIR3DL2interactor100ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
MAP17 (PF15807, IPR031627): Membrane-associated protein 117 kDa, PDZK1-interacting protein 1
68 LCP2interactor40.8331.633SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
SDA1 (PF05285, IPR007949): SDA1
SH2 (PF00017, IPR000980, SM00252): SH2 domain
69 LILRB1interactor31.0000Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
EphA2_TM (PF14575, IPR027936): Ephrin type-A receptor 2 transmembrane domain
SIT (PF15330): SHP2-interacting transmembrane adaptor protein, SIT
70 LMAN1interactor70.52431.830Lectin_leg-like (PF03388, IPR005052): Legume-like lectin family
Golgin_A5 (PF09787, IPR019177): Golgin subfamily A member 5
KxDL (PF10241, IPR019371): Uncharacterized conserved protein
DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404)
71 LRRK2oncoprotein80.28678.227Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain
DUF1043 (PF06295, IPR009386): Protein of unknown function (DUF1043)
T2SSE (PF00437, IPR001482): Type II/IV secretion system protein
Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase
Pkinase (PF00069, IPR000719): Protein kinase domain
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
PQQ_2 (PF13360, IPR002372): PQQ-like domain
LRR_8 (PF13855, IPR001611): Leucine rich repeat
COR (PF16095, IPR032171): C-terminal of Roc, COR, domain
72 MAGEA1interactor100MAGE (PF01454, IPR002190): MAGE family
MAGE_N (PF12440, IPR021072): Melanoma associated antigen family N terminal
73 MAGEA4interactor30.33346.950MAGE (PF01454, IPR002190): MAGE family
MAGE_N (PF12440, IPR021072): Melanoma associated antigen family N terminal
74 MAST2oncoprotein21.0000DUF1908 (PF08926, IPR015022): Domain of unknown function (DUF1908)
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
Pkinase (PF00069, IPR000719): Protein kinase domain
75 MEOX2interactor3090.700Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
76 MMS19interactor70.38133.244DUF3437 (PF11919, IPR021843): Domain of unknown function (DUF3437)
MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal
HEAT_2 (PF13646): HEAT repeats
MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II
77 NTRK1oncoprotein280.148798.249I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
78 PAXIP1interactor40.6672.929BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
IPT (PF01745, IPR002648, SM00429): Isopentenyl transferase
SURF6 (PF04935, IPR007019): Surfeit locus protein 6
DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052)
CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance
PTCB-BRCT (PF12738, IPR001357): twin BRCT domain
BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain
LIG3_BRCT (PF16759, IPR031916): DNA ligase 3 BRCT domain
RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain
79 PCDHB15oncoprotein21.0000Cadherin_2 (PF08266, IPR013164): Cadherin-like
Cadherin (PF00028, IPR002126, SM00112): Cadherin domain
Cadherin_3 (PF16184): Cadherin-like
Cadherin_C_2 (PF16492, IPR032455): Cadherin cytoplasmic C-terminal
80 PDCD6IPinteractor120.291122.168BRO1 (PF03097, IPR004328, SM01041): BRO1-like domain
MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
ALIX_LYPXL_bnd (PF13949, IPR025304): ALIX V-shaped domain binding to HIV
81 PPP1R21interactor2066.434TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
KLRAQ (PF10205, IPR019343): Predicted coiled-coil domain-containing protein
TTKRSYEDQ (PF10212, IPR019348): Predicted coiled-coil domain-containing protein
82 PPP6R1interactor60.267142.090CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain
SAPS (PF04499, IPR007587): SIT4 phosphatase-associated protein
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
83 PRG2interactor2011.224Lectin_C (PF00059, IPR001304, SM00034): Lectin C-type domain
DUF4628 (PF15429, IPR027851): Domain of unknown function (DUF4628)
84 PRR14interactor21.0000CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
Tantalus (PF15386, IPR028149): Drosophila Tantalus-like
85 PSMD2oncoprotein70.4769.551PC_rep (PF01851, IPR002015): Proteasome/cyclosome repeat
THAP (PF05485, IPR006612, SM00980): THAP domain
HEAT_2 (PF13646): HEAT repeats
86 PTCH1suppressor40.50023.371Patched (PF02460, IPR003392): Patched family
87 PTPN23suppressor70.47658.177BRO1 (PF03097, IPR004328, SM01041): BRO1-like domain
Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase
SOGA (PF11365, IPR027881): Protein SOGA
ALIX_LYPXL_bnd (PF13949, IPR025304): ALIX V-shaped domain binding to HIV
88 RPS6KB2interactor3026.140Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
89 SCARA3interactor100Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
Filament (PF00038, IPR001664): Intermediate filament protein
Flagellin_C (PF00700, IPR001029): Bacterial flagellin C-terminal helical region
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
zf-C2H2_10 (PF16588, IPR001878): C2H2 zinc-finger
90 SCLT1oncoprotein100DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
DUF641 (PF04859, IPR006943): Plant protein of unknown function (DUF641)
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
SlyX (PF04102, IPR007236): SlyX
XhlA (PF10779, IPR019715): Haemolysin XhlA
TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding
Imm7 (PF15585, IPR028965): Immunity protein 7
CCCAP (PF15964, IPR031887): Centrosomal colon cancer autoantigen protein family
DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082)
91 SEC61A1interactor70.52415.265DUF1430 (PF07242, IPR006541): Protein of unknown function (DUF1430)
SecY (PF00344, IPR002208): SecY translocase
Plug_translocon (PF10559, IPR019561): Plug domain of Sec61p
92 SH3GL1oncoprotein120.236124.936BAR (PF03114, IPR004148, SM00721): BAR domain
PhnG (PF06754, IPR009609): Phosphonate metabolism protein PhnG
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
93 SH3GL3interactor150.264152.380BAR (PF03114, IPR004148, SM00721): BAR domain
SH3_2 (PF07653, IPR011511): Variant SH3 domain
94 SH3KBP1protein found in more fusions150.352177.879Tmemb_cc2 (PF10267, IPR019394): Predicted transmembrane and coiled-coil 2 protein
SH3_9 (PF14604, IPR001452): Variant SH3 domain
95 STAT3suppressor70.400116.355SH2 (PF00017, IPR000980, SM00252): SH2 domain
STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain
STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain
STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain
96 SYNJ1interactor50.6002.769DUF1866 (PF08952, IPR015047, SM01165): Domain of unknown function (DUF1866)
Exo_endo_phos (PF03372, IPR005135): Endonuclease/Exonuclease/phosphatase family
Syja_N (PF02383, IPR002013): SacI homology domain
YppG (PF14179, IPR025555): YppG-like protein
97 SYNMsuppressor30.6670.654Filament (PF00038, IPR001664): Intermediate filament protein
CCDC-167 (PF15188, IPR028194): Coiled-coil domain-containing protein 167
98 SYVN1protein found in more fusions120.364152.273Alpha_GJ (PF03229, IPR004913): Alphavirus glycoprotein J
zf-DHHC (PF01529, IPR001594): DHHC palmitoyltransferase
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
99 TANGO2interactor100TANGO2 (PF05742, IPR008551): Transport and Golgi organisation 2
100 TAP1oncoprotein80.57111.108ABC_membrane (PF00664, IPR001140): ABC transporter transmembrane region
ABC_tran (PF00005, IPR003439): ABC transporter
SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
101 TAP2oncoprotein70.52469.471ABC_membrane (PF00664, IPR001140): ABC transporter transmembrane region
ABC_tran (PF00005, IPR003439): ABC transporter
SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
102 TAPBPinteractor70.6675.861C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
103 TCEA2interactor30.33340.824Med26 (PF08711, IPR017923): TFIIS helical bundle-like domain
TFIIS_C (PF01096, IPR001222): Transcription factor S-II (TFIIS)
TFIIS_M (PF07500, IPR003618): Transcription factor S-II (TFIIS), central domain
DUF4423 (PF14394, IPR025537): Domain of unknown function (DUF4423)
104 TERF1interactor50.33373.206TRF (PF08558, IPR013867): Telomere repeat binding factor (TRF)
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
105 TIAM2interactor21.0000PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
PH (PF00169, IPR001849, SM00233): PH domain
RBD (PF02196, IPR003116, SM00455): Raf-like Ras-binding domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
PH_6 (PF15406): Pleckstrin homology domain
106 TMEM108interactor100TMEM108 (PF15759, IPR031508): TMEM108 family
107 TMEM129interactor51.0000Tmpp129 (PF10272, IPR018801): Putative transmembrane protein precursor
108 TMEM17interactor70.28648.162Transmemb_17 (PF09799, IPR019184): Predicted membrane protein
DUF3043 (PF11241, IPR021403): Protein of unknown function (DUF3043)
109 TRAoncoprotein60.46770.122NA
110 TRAM1interactor40.83313.922TRAM1 (PF08390, IPR013599): TRAM1-like protein
TRAM_LAG1_CLN8 (PF03798, IPR006634): TLC domain
DUF3382 (PF11862, IPR021807): Domain of unknown function (DUF3382)
DUF3671 (PF12420, IPR022139): Protein of unknown function
111 TRBoncoprotein100NA
112 TYMSinteractor100Thymidylat_synt (PF00303, IPR000398): Thymidylate synthase
113 UBCprotein found in more fusions210.221548.852ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
114 UBE2J1interactor50.7003.364UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
ATPase-cat_bd (PF12156, IPR021993): Putative metal-binding domain of cation transport ATPase
115 UGGT1interactor30.6670.559Glyco_transf_8 (PF01501, IPR002495): Glycosyl transferase family 8
UDP-g_GGTase (PF06427, IPR009448): UDP-glucose:Glycoprotein Glucosyltransferase
116 VCPprotein found in more fusions180.257259.729AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2
CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain
TniB (PF05621, IPR008868): Bacterial TniB protein
Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain
DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944)
117 ZACNinteractor100Neur_chan_LBD (PF02931, IPR006202): Neurotransmitter-gated ion-channel ligand binding domain
Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
118 ZDHHC17protein found in more fusions40.33383.154zf-DHHC (PF01529, IPR001594): DHHC palmitoyltransferase
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_3 (PF13606, IPR002110): Ankyrin repeat
Ank_4 (PF13637): Ankyrin repeats (many copies)
119 ZNF219interactor21.0000Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zinc_ribbon_10 (PF10058, IPR019273): Predicted integral membrane zinc-ribbon metal-binding protein
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain
PRIMA1 (PF16101): Proline-rich membrane anchor 1
120 ZNF580interactor100zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
121 ZXDCinteractor21.0000zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-C2H2_8 (PF15909, IPR031799): C2H2-type zinc ribbon

B a c k    t o    T o p ⇑