Find Fusion Network

Visualization interactions

Powered by Cytoscape Web for: parental proteins CD63, HIF1A (from a repository: Sat Apr 15 13:08:44 2017)

Examples AFF1 MLL ACTN4 + MLLAFF1 + MLLALK + MSNALK + TFGALK + TPM3ALK + TPM4ASXL2 + KAT6AATF1 + FUSBCR + ABL1BCR + FGFR1CCND1 + TACSTD2CD74 + ROS1CDK6 + MLLCOL1A1 + PDGFBCREB3L2 + PPARGCREB3L2 + FUSCREBBP + KAT6ADAZAP1 + MEF2DELL + MLLEPS15 + MLLERG + EWSR1ERG + FUSERG + TMPRSS2ETV5 + TMPRSS2ETV6 + ABL1ETV6 + NTRK3ETV6 + PAX5EWSR1 + FLI1EWSR1 + WT1FOXO1 + PAX3FOXP1 + PAX5FRYL + MLLGAS7 + MLLGMPS + MLLGOLGA5 + RETHOOK3 + RETHOXC13 + NUP98HOXD13 + NUP98MECOM + RUNX1MKL1 + RBM15MLL + MLLT1MLL + MLLT4MLL + MLLT10MLL + PICALMMLLT10 + PICALMNCOA1 + PAX3NIN + PDGFRBNPM1 + RARANRG1 + ODZ4NTRK1 + TFGNUMA1 + RARANUP98 + PHF23PAX5 + ZNF521PBX1 + TCF3RET + TRIM27ROS1 + SLC34A2PML + RARAPRKAR1A + RARAPRKAR1A + RETRUNX1 + RUNX1T1RUNX1 + SH3D19	Cytoscape Web will replace the contents your graph	PPI Properties: Click on nodes or edges
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Statistics and Network structure information

Statistic of PPI Value(s) The number of interactors (fusion and proteins) 167 The number (and %) of the onco-proteins 61 (36.53 %) The number (and %) of the tumor suppressors 42 (25.15 %) Total number of binary PPIs (saturation %) 1254 (9.05 %) The number (and %) of affected PPIs 165 (13.16 %) The number of possible different fusions 45 PPI diameter 5 PPI radius 3 The average degree of PPI 14.024 Assortativity coefficient -0.2004 The network average Clustering coefficient 0.471 The number (and %) of a zero Clustering coefficients 12 (7.19 %) The number (and %) of a zero Betweenness Centrality 25 (14.97 %)

ACTIVE INTERACTORS

List of the fusions
PPI for parental proteins: CD63,HIF1A	All fusions
Proteins found in more fusions	MAPK1 (see 1 fusions); PLEKHA5 (see 1 fusions); HDAC7 (see 1 fusions); COMMD1 (see 1 fusions); LAMP2 (see 1 fusions); VHL (see 1 fusions); MYC (see 1 fusions); LGALS3 (see 2 fusions); SART3 (see 2 fusions); KAT2B (see 1 fusions); HIF1AN (see 1 fusions); PIAS1 (see 2 fusions); PSMA7 (see 2 fusions); COPS5 (see 1 fusions); RACK1/FN1 (see 1 fusions); HDAC5 (see 1 fusions); PARP1 (see 1 fusions); EP300 (see 1 fusions); OS9 (see 2 fusions); TP53 (see 3 fusions); SAT1 (see 5 fusions); TRAF6 (see 1 fusions); MCM7 (see 2 fusions); VCP (see 4 fusions); HSP90AA1 (see 2 fusions); TRIM28 (see 1 fusions); RHOBTB3 (see 1 fusions); HSP90AB1 (see 1 fusions); HDAC4 (see 1 fusions); SQSTM1 (see 5 fusions); NCOA1 (see 2 fusions); FAF1 (see 2 fusions); SP1 (see 1 fusions); CREBBP (see 6 fusions); STAT3 (see 2 fusions); USP20 (see 1 fusions); STUB1 (see 1 fusions); RACK1 (see 3 fusions); SHC1 (see 1 fusions); EPAS1 (see 1 fusions); RPTOR (see 3 fusions); PCGF2 (see 1 fusions); EGLN1 (see 1 fusions); SMAD3 (see 3 fusions);

List of active interactors

#	Name	Type	Number of PPI (degree)	Clustering Coefficient	Betweenness Centrality	Domains (Pfam, InterPro, SMART): description
1	CD63	parental protein	20	0.158	1006.924	Tetraspannin (PF00335, IPR018499): Tetraspanin family DUF4282 (PF14110, IPR025557): Domain of unknown function (DUF4282)
2	HIF1A	parental protein	145	0.089	14569.447	Dicty_REP (PF05086, IPR007778): Dictyostelium (Slime Mold) REP protein HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1
3	APEX1	interactor	10	0.578	8.635	Exo_endo_phos (PF03372, IPR005135): Endonuclease/Exonuclease/phosphatase family
4	ARNT	oncoprotein	10	0.467	12.842	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold PAS_11 (PF14598): PAS domain PRAS (PF15798, IPR026682): Proline-rich AKT1 substrate 1
5	ARNT2	interactor	2	1.000	0	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold PAP2 (PF01569, IPR000326, SM00014): PAP2 superfamily
6	ARNTL	suppressor	6	0.733	0.956	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold PAS_11 (PF14598): PAS domain
7	ATM	suppressor	17	0.475	33.738	FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain HEAT (PF02985, IPR000357): HEAT repeat PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase TAN (PF11640, IPR021668): Telomere-length maintenance and DNA damage repair ANAPC5 (PF12862, IPR026000): Anaphase-promoting complex subunit 5
8	ATP6V1B1	interactor	3	0.333	17.628	ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain DUF3533 (PF12051, IPR022703): Protein of unknown function (DUF3533)
9	BANP	suppressor	14	0.590	12.434	DUF1845 (PF08900, IPR014996): Domain of unknown function (DUF1845) BEN (PF10523, IPR018379, SM01025): BEN domain
10	BCL2	oncoprotein	11	0.622	4.716	Bcl-2 (PF00452, IPR026298): Apoptosis regulator proteins, Bcl-2 family BH4 (PF02180, IPR003093, SM00265): Bcl-2 homology region 4
11	BCR	suppressor	11	0.509	147.870	Bcr-Abl_Oligo (PF09036, IPR015123): Bcr-Abl oncoprotein oligomerisation domain C2 (PF00168, IPR000008, SM00239): C2 domain PH (PF00169, IPR001849, SM00233): PH domain RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain IQ_SEC7_PH (PF16453, IPR001849): PH domain
12	BHLHE41	suppressor	4	1.000	0	Adeno_PIX (PF03955, IPR005641): Adenovirus hexon-associated protein (IX) Hairy_orange (PF07527, IPR003650): Hairy Orange HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence
13	BRCA1	suppressor	42	0.299	449.687	BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT
14	C19orf70	interactor	1	0	0	QIL1 (PF15884, IPR026769): Protein QIL1
15	CAPN1	interactor	6	0.400	30.153	Calpain_III (PF01067, IPR022682, SM00720): Calpain large subunit, domain III Peptidase_C2 (PF00648, IPR001300, SM00230): Calpain family cysteine protease EF-hand_6 (PF13405, IPR002048): EF-hand domain EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
16	CD81	interactor	11	0.289	292.200	Tetraspannin (PF00335, IPR018499): Tetraspanin family
17	CD82	suppressor	7	0.476	56.572	Tetraspannin (PF00335, IPR018499): Tetraspanin family
18	CD9	oncoprotein	8	0.464	25.284	Tetraspannin (PF00335, IPR018499): Tetraspanin family
19	CDC34	oncoprotein	9	0.464	94.265	UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
20	CDK8	interactor	19	0.529	39.546	Pkinase (PF00069, IPR000719): Protein kinase domain
21	CDKN2A	suppressor	24	0.482	50.753	Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_5 (PF13857): Ankyrin repeats (many copies)
22	CEP350	interactor	4	0.667	2.502	CAP_GLY (PF01302, IPR000938, SM01052): CAP-Gly domain Coatamer_beta_C (PF07718, IPR011710): Coatomer beta C-terminal region MAS20 (PF02064, IPR002056): MAS20 protein import receptor Mucin (PF01456, IPR000458): Mucin-like glycoprotein Topoisom_I_N (PF02919, IPR008336): Eukaryotic DNA topoisomerase I, DNA binding fragment Complex1_LYR_2 (PF13233): Complex1_LYR-like AAA_23 (PF13476): AAA domain MAP17 (PF15807, IPR031627): Membrane-associated protein 117 kDa, PDZK1-interacting protein 1
23	COMMD1	protein found in more fusions	10	0.583	6.008	COMMD1_N (PF17221): COMMD1 N-terminal domain COMM_domain (PF07258): COMM domain
24	COPS5	protein found in more fusions	30	0.335	144.954	JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
25	CREBBP	suppressor	36	0.445	166.416	Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain MAS20 (PF02064, IPR002056): MAS20 protein import receptor TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26 HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729) DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834)
26	CTNNB1	oncoprotein	24	0.366	236.935	Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361) HEAT_EZ (PF13513): HEAT-like repeat
27	CUL2	suppressor	27	0.325	144.392	Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
28	DAP3	interactor	5	1.000	0	DAP3 (PF10236, IPR019368): Mitochondrial ribosomal death-associated protein 3
29	DCUN1D1	interactor	12	0.606	11.736	Cullin_binding (PF03556, IPR005176): Cullin binding UBA_4 (PF14555): UBA-like domain
30	DNAJB1	suppressor	9	0.556	7.543	DnaJ (PF00226, IPR001623, SM00271): DnaJ domain DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
31	EAF2	suppressor	1	0	0	Paf1 (PF03985, IPR007133): Paf1 EAF (PF09816, IPR019194): RNA polymerase II transcription elongation factor DUF4482 (PF14818, IPR027882): Domain of unknown function (DUF4482)
32	EGLN1	suppressor	12	0.364	32.955	zf-MYND (PF01753, IPR002893): MYND finger 2OG-FeII_Oxy_3 (PF13640, IPR005123): 2OG-Fe(II) oxygenase superfamily
33	EGLN2	interactor	4	1.000	0	2OG-FeII_Oxy_3 (PF13640, IPR005123): 2OG-Fe(II) oxygenase superfamily
34	EGLN3	suppressor	10	0.389	20.166	2OG-FeII_Oxy_3 (PF13640, IPR005123): 2OG-Fe(II) oxygenase superfamily
35	EP300	oncoprotein	46	0.299	638.606	Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
36	EPAS1	suppressor	33	0.204	297.323	Corona_I (PF03187, IPR004876): Corona nucleocapsid I protein HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1 PAS_11 (PF14598): PAS domain
37	ESR1	suppressor	51	0.300	491.357	Oest_recep (PF02159, IPR001292): Oestrogen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal
38	F12	interactor	4	0.667	0.452	EGF (PF00008, IPR000742, SM00181): EGF-like domain fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain Kringle (PF00051, IPR000001): Kringle domain Trypsin (PF00089, IPR001254, SM00020): Trypsin
39	FAF1	protein found in more fusions	12	0.527	14.455	UBX (PF00789, IPR001012, SM00166): UBX domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family AAA_11 (PF13086): AAA domain UBA_4 (PF14555): UBA-like domain
40	FAF2	interactor	12	0.382	27.327	DUF1682 (PF07946, IPR012879): Protein of unknown function (DUF1682) UBX (PF00789, IPR001012, SM00166): UBX domain Thioredoxin_7 (PF13899): Thioredoxin-like UBA_4 (PF14555): UBA-like domain
41	FAM134C	interactor	1	0	0	Reticulon (PF02453, IPR003388): Reticulon
42	FBXW7	suppressor	19	0.301	87.412	Mem_trans (PF03547, IPR004776): Membrane transport protein WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 F-box-like (PF12937, IPR001810): F-box-like
43	FDX1	interactor	1	0	0	Fer2 (PF00111, IPR001041): 2Fe-2S iron-sulfur cluster binding domain
44	FHL2	oncoprotein	20	0.374	166.469	LIM (PF00412, IPR001781, SM00132): LIM domain zf-ribbon_3 (PF13248): zinc-ribbon domain
45	FN1	oncoprotein	25	0.247	591.372	fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
46	GKAP1	interactor	4	0.667	1.648	CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H) Ribosomal_L30_N (PF08079, IPR012988): Ribosomal L30 N-terminal domain PKcGMP_CC (PF16808, IPR031831): Coiled-coil N-terminus of cGMP-dependent protein kinase
47	GPLD1	interactor	3	1.000	0	FG-GAP (PF01839, IPR013517): FG-GAP repeat Zn_dep_PLPC (PF00882, IPR029002, SM00770): Zinc dependent phospholipase C
48	HDAC1	suppressor	40	0.387	210.565	FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
49	HDAC2	suppressor	25	0.464	48.595	Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1
50	HDAC3	suppressor	27	0.391	114.167	Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
51	HDAC4	oncoprotein	14	0.551	31.597	Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
52	HDAC5	protein found in more fusions	22	0.419	50.905	Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain NOA36 (PF06524, IPR010531): NOA36 protein Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3 HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
53	HDAC6	oncoprotein	21	0.284	276.296	Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain PSGP (PF07276, IPR009900): Apopolysialoglycoprotein (PSGP) zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein
54	HDAC7	protein found in more fusions	11	0.667	3.603	Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain PRIMA1 (PF16101): Proline-rich membrane anchor 1 CBP_BcsO (PF17037, IPR031484): Cellulose biosynthesis protein BcsO
55	HEXIM1	oncoprotein	8	0.679	5.567	APG6 (PF04111, IPR007243): Autophagy protein Apg6 DivIC (PF04977, IPR007060): Septum formation initiator Shugoshin_N (PF07558, IPR011516): Shugoshin N-terminal coiled-coil region HEXIM (PF15313, IPR024872): Hexamethylene bis-acetamide-inducible protein
56	HIF1AN	protein found in more fusions	8	0.476	9.696	Cupin_8 (PF13621): Cupin-like domain
57	HLA-DMB	interactor	4	0.500	94.126	MHC_II_beta (PF00969, IPR000353, SM00921): Class II histocompatibility antigen, beta domain C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
58	HLA-DOB	interactor	2	1.000	0	MHC_II_beta (PF00969, IPR000353, SM00921): Class II histocompatibility antigen, beta domain C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
59	HLA-DRA	interactor	7	0.381	277.772	MHC_II_alpha (PF00993, IPR001003, SM00920): Class II histocompatibility antigen, alpha domain C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain C1-set_C (PF16196, IPR032431): C1-set C-terminal domain
60	HSP90AA1	oncoprotein	44	0.240	665.767	HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein
61	HSP90AB1	oncoprotein	24	0.379	206.943	HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein
62	HSPA4	interactor	32	0.321	176.333	Herpes_ICP4_N (PF03584, IPR005206): Herpesvirus ICP4-like protein N-terminal region HSP70 (PF00012, IPR013126): Hsp70 protein TP53IP5 (PF15331, IPR029290): Cellular tumour antigen p53-inducible 5
63	HSPA8	oncoprotein	31	0.348	299.117	HSP70 (PF00012, IPR013126): Hsp70 protein
64	ING1	suppressor	11	0.727	3.178	PHD (PF00628, IPR019787, SM00249): PHD-finger NPR3 (PF03666, IPR005365): Nitrogen Permease regulator of amino acid transport activity 3 ING (PF12998, IPR024610): Inhibitor of growth proteins N-terminal histone-binding zf-C4pol (PF14260, IPR025687): C4-type zinc-finger of DNA polymerase delta
65	ITGB1	suppressor	10	0.289	245.012	EGF_2 (PF07974, IPR013111): EGF-like domain Integrin_b_cyt (PF08725, IPR014836): Integrin beta cytoplasmic domain Integrin_B_tail (PF07965, IPR012896): Integrin beta tail domain Integrin_beta (PF00362, IPR002369, SM00187): Integrin, beta chain PSI_integrin (PF17205): Integrin plexin domain
66	JUN	oncoprotein	31	0.428	93.939	bZIP_1 (PF00170, IPR004827): bZIP transcription factor Jun (PF03957, IPR005643): Jun-like transcription factor
67	KAT2B	protein found in more fusions	25	0.413	73.794	Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family PCAF_N (PF06466, IPR009464): PCAF (P300/CBP-associated factor) N-terminal domain Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
68	KDM3A	suppressor	1	0	0	C1_2 (PF03107, IPR004146): C1 domain JmjC (PF02373, IPR003347, SM00558): JmjC domain, hydroxylase
69	KIT	oncoprotein	5	0.300	98.037	ig (PF00047, IPR013151, SM00409): Immunoglobulin domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Ig_2 (PF13895, IPR007110): Immunoglobulin domain Ig_3 (PF13927): Immunoglobulin domain
70	LAMP2	protein found in more fusions	8	0.190	384.443	Lamp (PF01299, IPR002000): Lysosome-associated membrane glycoprotein (Lamp)
71	LGALS3	oncoprotein	12	0.200	350.197	Gal-bind_lectin (PF00337, IPR001079, SM00908): Galactoside-binding lectin
72	LGALS8	interactor	7	0.286	77.761	Gal-bind_lectin (PF00337, IPR001079, SM00908): Galactoside-binding lectin
73	LGALS9	interactor	7	0.381	91.566	Gal-bind_lectin (PF00337, IPR001079, SM00908): Galactoside-binding lectin Peptidase_C62 (PF12380, IPR024348): Gill-associated viral 3C-like peptidase
74	LYSMD2	interactor	1	0	0	LysM (PF01476, IPR018392, SM00257): LysM domain HCV_NS5a_C (PF12941, IPR024350): HCV NS5a protein C-terminal region
75	MAFG	oncoprotein	4	0.667	0.205	bZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor ThrE_2 (PF12821, IPR024528): Threonine/Serine exporter, ThrE
76	MAFK	oncoprotein	9	0.833	0.741	bZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor
77	MAPK1	oncoprotein	24	0.368	98.218	Pkinase (PF00069, IPR000719): Protein kinase domain
78	MAX	suppressor	12	0.455	17.326	ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain SlyX (PF04102, IPR007236): SlyX
79	MCM3	interactor	11	0.491	11.090	MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain
80	MCM7	protein found in more fusions	17	0.283	58.592	MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain
81	MDM2	oncoprotein	41	0.285	635.636	Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region Presenilin (PF01080, IPR001108): Presenilin SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain zf-FPG_IleRS (PF06827, IPR010663): Zinc finger found in FPG and IleRS zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
82	MED12	oncoprotein	10	0.756	3.753	Med12 (PF09497, IPR019035): Transcription mediator complex subunit Med12 Peptidase_S15 (PF02129, IPR000383): X-Pro dipeptidyl-peptidase (S15 family) DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19 DUF2877 (PF11392, IPR021530): Protein of unknown function (DUF2877) Med12-PQL (PF12144, IPR021989): Eukaryotic Mediator 12 catenin-binding domain Med12-LCEWAV (PF12145, IPR021990): Eukaryotic Mediator 12 subunit domain CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance
83	MED13	oncoprotein	8	0.929	0.417	Med13_C (PF06333, IPR009401): Mediator complex subunit 13 C-terminal Med13_N (PF11597, IPR021643): Mediator complex subunit 13 N-terminal
84	MED13L	interactor	5	1.000	0	Totivirus_coat (PF05518, IPR008871): Totivirus coat protein Med13_C (PF06333, IPR009401): Mediator complex subunit 13 C-terminal Med13_N (PF11597, IPR021643): Mediator complex subunit 13 N-terminal
85	MED14	interactor	11	0.636	13.596	Med14 (PF08638, IPR013947): Mediator complex subunit MED14
86	MED15	interactor	10	0.689	5.101	Med15 (PF09606, IPR019087): ARC105 or Med15 subunit of Mediator complex non-fungal
87	MED23	interactor	17	0.485	39.416	Med23 (PF11573, IPR021629): Mediator complex subunit 23
88	MID2	interactor	8	0.333	162.954	fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain SPRY (PF00622, IPR003877, SM00449): SPRY domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger CEBP_ZZ (PF16366, IPR032296): Cytoplasmic polyadenylation element-binding protein ZZ domain APC_u15 (PF16636): Unstructured region on APC between APC_crr regions 5 and 6
89	MTA1	oncoprotein	12	0.591	21.893	BAH (PF01426, IPR001025, SM00439): BAH domain ELM2 (PF01448, IPR000949): ELM2 domain Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain GATA (PF00320, IPR000679, SM00401): GATA zinc finger
90	MYC	oncoprotein	37	0.378	169.297	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain Myc_N (PF01056, IPR012682): Myc amino-terminal region
91	NAA10	oncoprotein	3	0.667	0.500	Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family
92	NBEAL1	interactor	1	0	0	Beach (PF02138, IPR000409, SM01026): Beige/BEACH domain WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Laminin_G_3 (PF13385): Concanavalin A-like lectin/glucanases superfamily PH_BEACH (PF14844, IPR023362): PH domain associated with Beige/BEACH DUF4704 (PF15787, IPR031570): Domain of unknown function (DUF4704) DUF4800 (PF16057): Domain of unknown function (DUF4800)
93	NCOA1	oncoprotein	17	0.558	43.251	DUF1518 (PF07469, IPR010011, SM01151): Domain of unknown function (DUF1518) HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Nuc_rec_co-act (PF08815, IPR014920): Nuclear receptor coactivator PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold SRC-1 (PF08832, IPR014935): Steroid receptor coactivator PAS_11 (PF14598): PAS domain DUF4927 (PF16279, IPR032565): Domain of unknown function (DUF4927) NCOA_u2 (PF16665): Unstructured region on nuclear receptor coactivator protein
94	NDN	suppressor	6	0.500	3.476	MAGE (PF01454, IPR002190): MAGE family
95	NES	interactor	4	0.333	87.560	Anthrax-tox_M (PF09156, IPR015239): Anthrax toxin lethal factor, middle domain Filament (PF00038, IPR001664): Intermediate filament protein HSCB_C (PF07743, IPR009073): HSCB C-terminal oligomerisation domain OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) Prominin (PF05478, IPR008795): Prominin
96	NLN	interactor	1	0	0	Peptidase_M3 (PF01432, IPR001567): Peptidase family M3
97	NR4A1	suppressor	15	0.438	25.018	zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
98	NSFL1C	interactor	6	1.000	0	SEP (PF08059, IPR012989, SM00553): SEP domain UBX (PF00789, IPR001012, SM00166): UBX domain UBA_4 (PF14555): UBA-like domain
99	OS9	protein found in more fusions	7	0.467	5.727	DNA_pol_phi (PF04931, IPR007015): DNA polymerase phi Nucleo_P87 (PF07267, IPR009893): Nucleopolyhedrovirus capsid protein P87 PRKCSH (PF07915, IPR012913): Glucosidase II beta subunit-like protein Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein PRKCSH_1 (PF13015, IPR009011): Glucosidase II beta subunit-like protein
100	OTUD7B	interactor	4	0.500	3.204	OTU (PF02338, IPR003323): OTU-like cysteine protease zf-A20 (PF01754, IPR002653, SM00259): A20-like zinc finger UBA_4 (PF14555): UBA-like domain CCDC106 (PF15794, IPR031591): Coiled-coil domain-containing protein 106
101	PARP1	suppressor	31	0.377	238.481	BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain PADR1 (PF08063, IPR012982): PADR1 (NUC008) domain PARP (PF00644, IPR012317): Poly(ADP-ribose) polymerase catalytic domain PARP_reg (PF02877, IPR004102): Poly(ADP-ribose) polymerase, regulatory domain WGR (PF05406, IPR008893, SM00773): WGR domain zf-PARP (PF00645, IPR001510): Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region
102	PCGF2	suppressor	4	0.667	0.182	zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
103	PIAS1	suppressor	8	0.905	0.247	Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein zf-MIZ (PF02891, IPR004181): MIZ/SP-RING zinc finger PINIT (PF14324, IPR023321): PINIT domain UPF0544 (PF15749, IPR032739): Uncharacterised protein family UPF0544
104	PKM	oncoprotein	17	0.324	281.552	PK (PF00224, IPR015793): Pyruvate kinase, barrel domain PK_C (PF02887, IPR015795): Pyruvate kinase, alpha/beta domain
105	PLD1	suppressor	4	0.833	0.340	PH (PF00169, IPR001849, SM00233): PH domain PLDc (PF00614, IPR001736, SM00155): Phospholipase D Active site motif PX (PF00787, IPR001683, SM00312): PX domain PLDc_2 (PF13091, IPR025202): PLD-like domain
106	PLD2	interactor	5	0.600	3.136	PH (PF00169, IPR001849, SM00233): PH domain PLDc (PF00614, IPR001736, SM00155): Phospholipase D Active site motif PX (PF00787, IPR001683, SM00312): PX domain PLDc_2 (PF13091, IPR025202): PLD-like domain
107	PLEKHA5	protein found in more fusions	4	0.667	1.000	PH (PF00169, IPR001849, SM00233): PH domain WW (PF00397, IPR001202, SM00456): WW domain MKLP1_Arf_bdg (PF16540, IPR032384): Arf6-interacting domain of mitotic kinesin-like protein 1
108	PSMA7	protein found in more fusions	10	0.556	5.555	Proteasome (PF00227, IPR001353): Proteasome subunit Peptidase_C65 (PF10275, IPR019400): Peptidase C65 Otubain Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
109	PSMC3	interactor	13	0.455	15.673	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) DUF3713 (PF12506, IPR022186): Protein of unknown function (DUF3713) JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II
110	PSMD10	interactor	11	0.582	8.774	Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies)
111	PTGES3	interactor	10	0.611	9.434	CS (PF04969, IPR007052): CS domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
112	PTGFRN	interactor	7	0.476	19.117	V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_2 (PF13895, IPR007110): Immunoglobulin domain Ig_3 (PF13927): Immunoglobulin domain
113	RACK1	suppressor	18	0.279	317.441	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
114	RAD23B	suppressor	6	0.467	3.739	K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain XPC-binding (PF09280, IPR015360): XPC-binding domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family DUF3123 (PF11321, IPR021470): Protein of unknown function (DUF3123)
115	RB1	suppressor	23	0.423	66.484	RB_A (PF01858, IPR002720): Retinoblastoma-associated protein A domain RB_B (PF01857, IPR002719): Retinoblastoma-associated protein B domain Rb_C (PF08934, IPR015030): Rb C-terminal domain DUF3452 (PF11934, IPR024599): Domain of unknown function (DUF3452) DUF4592 (PF15262, IPR028030): Domain of unknown function (DUF4592)
116	RBX1	oncoprotein	18	0.397	49.175	zf-rbx1 (PF12678, IPR024766): RING-H2 zinc finger domain
117	RELA	oncoprotein	37	0.333	288.034	DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
118	RHOBTB3	protein found in more fusions	6	0.700	1.033	BTB (PF00651, IPR013069, SM00225): BTB/POZ domain Ras (PF00071, IPR001806, SM00173): Ras family
119	RNF13	interactor	7	0.143	169.260	DNA_ligase_ZBD (PF03119, IPR004149): NAD-dependent DNA ligase C4 zinc finger domain PA (PF02225, IPR003137): PA domain zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain FAM176 (PF14851): FAM176 family STAC2_u1 (PF16664): Unstructured on SH3 and cysteine-rich domain-containing protein 2
120	RPTOR	protein found in more fusions	8	0.476	8.150	HEAT (PF02985, IPR000357): HEAT repeat WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain HEAT_2 (PF13646): HEAT repeats Raptor_N (PF14538, IPR029347): Raptor N-terminal CASPase like domain
121	RUNX2	suppressor	18	0.471	30.668	DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180) Runt (PF00853, IPR013524): Runt domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) DUF2722 (PF10846, IPR021216): Protein of unknown function (DUF2722)
122	RUVBL2	oncoprotein	16	0.533	17.494	TIP49 (PF06068, IPR010339): TIP49 C-terminus
123	RWDD3	interactor	3	0.667	0.182	DUF1115 (PF06544, IPR010541): Protein of unknown function (DUF1115) RWD (PF05773, IPR006575, SM00591): RWD domain
124	SART3	protein found in more fusions	3	1.000	0	CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H) DUF1866 (PF08952, IPR015047, SM01165): Domain of unknown function (DUF1866) DUF1993 (PF09351, IPR018531): Domain of unknown function (DUF1993) Lsm_interact (PF05391, IPR008669): Lsm interaction motif Phage_GPD (PF05954): Phage late control gene D protein (GPD) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Suf (PF05843, IPR008847): Suppressor of forked protein (Suf) TPR_14 (PF13428): Tetratricopeptide repeat MRI (PF15325, IPR028278): Modulator of retrovirus infection LSM_int_assoc (PF16605): LSM-interacting associated unstructured
125	SAT1	protein found in more fusions	8	0.333	131.542	Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family
126	SAT2	interactor	6	0.600	3.197	Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family
127	SDC1	oncoprotein	3	0.333	50.874	Herpes_TAF50 (PF03326, IPR004998): Herpesvirus transcription activation factor (transactivator) Syndecan (PF01034, IPR027789): Syndecan domain DUF3592 (PF12158, IPR021994): Protein of unknown function (DUF3592) AJAP1_PANP_C (PF15298, IPR029198): AJAP1/PANP C-terminus
128	SDCBP	interactor	8	0.143	276.660	PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
129	SENP3	interactor	14	0.527	13.168	Nop53 (PF07767, IPR011687): Nop53 (60S ribosomal biogenesis) Peptidase_C48 (PF02902, IPR003653): Ulp1 protease family, C-terminal catalytic domain
130	SEPT9	oncoprotein	2	1.000	0	Septin (PF00735, IPR000038): Septin DUF3306 (PF11748, IPR021735): Protein of unknown function (DUF3306)
131	SHC1	oncoprotein	9	0.571	4.658	PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) SH2 (PF00017, IPR000980, SM00252): SH2 domain
132	SIN3A	oncoprotein	19	0.491	31.811	Sin3_corepress (PF08295, IPR013194, SM00761): Sin3 family co-repressor PAH (PF02671, IPR003822, SM00309): Paired amphipathic helix repeat Sin3a_C (PF16879, IPR031693): C-terminal domain of Sin3a protein
133	SMAD3	oncoprotein	33	0.393	125.865	MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain
134	SMARCA2	suppressor	16	0.592	152.391	DUF1168 (PF06658, IPR009548): Protein of unknown function (DUF1168) DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840) HSA (PF07529, IPR014012, SM00573): HSA QLQ (PF08880, IPR014978, SM00951): QLQ SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain YL1 (PF05764, IPR008895): YL1 nuclear protein BRK (PF07533, IPR006576, SM00592): BRK domain DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052) EPL1 (PF10513, IPR019542): Enhancer of polycomb-like Bromodomain (PF00439, IPR001487, SM00297): Bromodomain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain SnAC (PF14619, IPR029295): Snf2-ATP coupling, chromatin remodelling complex WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
135	SMARCA4	suppressor	26	0.489	87.895	DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840) HSA (PF07529, IPR014012, SM00573): HSA QLQ (PF08880, IPR014978, SM00951): QLQ SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain BRK (PF07533, IPR006576, SM00592): BRK domain Bromodomain (PF00439, IPR001487, SM00297): Bromodomain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal DUF4065 (PF13274, IPR025272): Protein of unknown function (DUF4065) SnAC (PF14619, IPR029295): Snf2-ATP coupling, chromatin remodelling complex WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
136	SP1	protein found in more fusions	29	0.521	89.252	zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Miga (PF10265, IPR019392): Mitoguardin zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
137	SQSTM1	oncoprotein	18	0.338	117.168	PB1 (PF00564, IPR000270, SM00666): PB1 domain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type UBA_5 (PF16577, IPR015940): UBA domain
138	SRC	oncoprotein	16	0.362	225.438	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
139	SRF	interactor	11	0.356	265.074	SRF-TF (PF00319, IPR002100, SM00432): SRF-type transcription factor (DNA-binding and dimerisation domain)
140	SSX4	oncoprotein	1	0	0	KRAB (PF01352, IPR001909, SM00349): KRAB box SSXRD (PF09514, IPR019041): SSXRD motif
141	STAT3	suppressor	26	0.417	66.818	SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain
142	STUB1	suppressor	26	0.370	97.258	U-box (PF04564, IPR003613, SM00504): U-box domain ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 (PF13414, IPR011990): TPR repeat TPR_20 (PF14561): Tetratricopeptide repeat
143	TCEANC2	interactor	1	0	0	Med26 (PF08711, IPR017923): TFIIS helical bundle-like domain
144	TCEB1	oncoprotein	14	0.462	32.750	Skp1_POZ (PF03931, IPR016073): Skp1 family, tetramerisation domain
145	TCEB2	interactor	11	0.655	9.715	ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
146	TP53	suppressor	56	0.271	560.669	DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
147	TRAF6	protein found in more fusions	21	0.211	265.991	SlyX (PF04102, IPR007236): SlyX zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
148	TRIM28	protein found in more fusions	28	0.356	125.470	ASFV_J13L (PF05568, IPR008385): African swine fever virus J13L protein K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain PHD (PF00628, IPR019787, SM00249): PHD-finger FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain SKA2 (PF16740, IPR026762): Spindle and kinetochore-associated protein 2
149	TSPAN3	interactor	3	0.667	1.470	Hum_adeno_E3A (PF05393, IPR008652): Human adenovirus early E3A glycoprotein Tetraspannin (PF00335, IPR018499): Tetraspanin family
150	TTC1	interactor	5	0.700	1.489	TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat
151	UACA	interactor	3	0.667	1.000	APG6 (PF04111, IPR007243): Autophagy protein Apg6 DivIC (PF04977, IPR007060): Septum formation initiator Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family MAD (PF05557, IPR008672): Mitotic checkpoint protein TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein Tropomyosin (PF00261, IPR000533): Tropomyosin Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease SHE3 (PF17078, IPR031398): SWI5-dependent HO expression protein 3
152	UBE2D1	interactor	21	0.295	290.611	UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
153	UBE2I	interactor	28	0.353	187.036	UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
154	UBXN1	interactor	15	0.330	192.026	Selenoprotein_S (PF06936, IPR009703): Selenoprotein S (SelS) UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain UBX (PF00789, IPR001012, SM00166): UBX domain
155	UBXN7	interactor	14	0.451	30.537	UBX (PF00789, IPR001012, SM00166): UBX domain UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif Thioredoxin_7 (PF13899): Thioredoxin-like UBA_4 (PF14555): UBA-like domain
156	USP19	interactor	5	0.700	1.443	CS (PF04969, IPR007052): CS domain UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase USP19_linker (PF16602): Linker region of USP19 deubiquitinase
157	USP20	protein found in more fusions	4	0.667	0.222	UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein DUSP (PF06337, IPR006615, SM00695): DUSP domain
158	UTP23	interactor	2	1.000	0	Fcf1 (PF04900, IPR006984): Fcf1
159	VCP	protein found in more fusions	32	0.292	347.446	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2 CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain TniB (PF05621, IPR008868): Bacterial TniB protein Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944)
160	VHL	suppressor	44	0.216	569.366	Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP) VHL (PF01847, IPR022772): von Hippel-Lindau disease tumour suppressor protein VHL_C (PF17211): VHL box domain
161	VHLL	suppressor	1	0	0	VHL (PF01847, IPR022772): von Hippel-Lindau disease tumour suppressor protein
162	VKORC1	interactor	6	0.300	100.662	VKOR (PF07884, IPR012932, SM00756): Vitamin K epoxide reductase family
163	WWOX	suppressor	9	0.639	9.567	adh_short (PF00106, IPR002198): short chain dehydrogenase WW (PF00397, IPR001202, SM00456): WW domain
164	WWTR1	interactor	1	0	0	WW (PF00397, IPR001202, SM00456): WW domain
165	ZC3H12A	interactor	5	0.667	0.688	RNase_Zc3h12a (PF11977, IPR021869): Zc3h12a-like Ribonuclease NYN domain zf-CCCH_2 (PF14608): RNA-binding, Nab2-type zinc finger
166	ZNF197	interactor	3	1.000	0	KRAB (PF01352, IPR001909, SM00349): KRAB box SCAN (PF02023, IPR003309, SM00431): SCAN domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger
167	ZNF518A	interactor	2	1.000	0	CBP4 (PF07960, IPR012420): CBP4 zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Fer4_9 (PF13187, IPR017896): 4Fe-4S dicluster domain zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain

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