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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)247
The number (and %) of the onco-proteins79 (31.98 %)
The number (and %) of the tumor suppressors34 (13.77 %)
Total number of binary PPIs (saturation %)1592 (5.24 %)
The number (and %) of affected PPIs246 (15.45 %)
The number of possible different fusions39
PPI diameter5
PPI radius3
The average degree of PPI12.243
Assortativity coefficient-0.2576
The network average Clustering coefficient0.463
The number (and %) of a zero Clustering coefficients20 (8.10 %)
The number (and %) of a zero Betweenness Centrality33 (13.36 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: SMARCD2,SH3KBP1 All fusions
Proteins found in more fusions NTRK1/HNRNPC (see 1 fusions); PPFIBP1 (see 1 fusions); CKAP4 (see 5 fusions); CBL (see 1 fusions); PLEKHA5 (see 1 fusions); CUL3 (see 1 fusions); GRB2 (see 1 fusions); SMARCB1 (see 12 fusions); FYN (see 1 fusions); MYC (see 1 fusions); TNFRSF1A (see 3 fusions); NUP153 (see 2 fusions); PIK3R1 (see 1 fusions); SMARCC1 (see 2 fusions); SAMHD1 (see 1 fusions); PAK2 (see 2 fusions); UBC (see 1 fusions); SS18 (see 1 fusions); RPA1 (see 1 fusions); TP53 (see 3 fusions); ITSN2 (see 1 fusions); LYN (see 2 fusions); SH3GL2 (see 1 fusions); FRS3 (see 1 fusions); PABPC1 (see 2 fusions); PDCD6 (see 1 fusions); LCK (see 1 fusions); IMPDH2 (see 2 fusions); CD2AP (see 1 fusions); KHDRBS1 (see 1 fusions); SH3KBP1 (see 1 fusions); EGFR (see 2 fusions); HNRNPC (see 1 fusions); PTK2 (see 2 fusions); DDX17 (see 3 fusions); ATP5A1 (see 1 fusions); TBL1X (see 2 fusions); CBLB (see 4 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 SMARCD2parental protein460.2252448.489SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain
2 SH3KBP1parental protein2000.03733894.547Tmemb_cc2 (PF10267, IPR019394): Predicted transmembrane and coiled-coil 2 protein
SH3_9 (PF14604, IPR001452): Variant SH3 domain
3 ABL1oncoprotein210.468151.638Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
F_actin_bind (PF08919, IPR015015, SM00808): F-actin binding
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
FRG2 (PF15315, IPR026245): Facioscapulohumeral muscular dystrophy candidate 2
4 ACTC1interactor50.50040.690Actin (PF00022, IPR004000, SM00268): Actin
5 ACTL6Ainteractor250.530364.731Actin (PF00022, IPR004000, SM00268): Actin
6 ANAPC4interactor80.95210.217ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
ANAPC4 (PF12896, IPR024790): Anaphase-promoting complex, cyclosome, subunit 4
7 ANAPC5interactor90.69432.737TPR_4 (PF07721, IPR011717): Tetratricopeptide repeat
ANAPC5 (PF12862, IPR026000): Anaphase-promoting complex subunit 5
TPR_6 (PF13174, IPR019734): Tetratricopeptide repeat
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_16 (PF13432): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
8 ANAPC7interactor100.69433.595TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
TPR_21 (PF09976, IPR018704): Tetratricopeptide repeat-like domain
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
TPR_7 (PF13176, IPR019734): Tetratricopeptide repeat
TPR_14 (PF13428): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
9 ANLNoncoprotein160.31771.231Anillin (PF08174, IPR012966): Cell division protein anillin
PH (PF00169, IPR001849, SM00233): PH domain
Anillin_N (PF16018, IPR031970): Anillin N-terminus
10 ARAP1interactor50.5005.302ArfGap (PF01412, IPR001164, SM00105): Putative GTPase activating protein for Arf
PH (PF00169, IPR001849, SM00233): PH domain
RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain
RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
11 ARAP3interactor30.6671.106ArfGap (PF01412, IPR001164, SM00105): Putative GTPase activating protein for Arf
PH (PF00169, IPR001849, SM00233): PH domain
RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain
RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
12 ARHGAP17interactor120.42431.508BAR (PF03114, IPR004148, SM00721): BAR domain
RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
13 ARHGAP27interactor100PH (PF00169, IPR001849, SM00233): PH domain
RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
RNA_pol_Rpb1_R (PF05001, IPR000684): RNA polymerase Rpb1 C-terminal repeat
WW (PF00397, IPR001202, SM00456): WW domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
14 ARHGEF1interactor40.3332.608RGS-like (PF09128, IPR015212): Regulator of G protein signalling-like domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
Syntaxin_2 (PF14523): Syntaxin-like protein
PH_13 (PF16652, IPR001849): Pleckstrin homology domain
15 ARID1Asuppressor210.681182.489ARID (PF01388, IPR001606, SM00501): ARID/BRIGHT DNA binding domain
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
TAF4 (PF05236, IPR007900): Transcription initiation factor TFIID component TAF4 family
YscJ_FliF_C (PF08345, IPR013556): Flagellar M-ring protein C-terminal
TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence
BAF250_C (PF12031, IPR021906): SWI/SNF-like complex subunit BAF250/Osa
Keratin_2_tail (PF16210, IPR032449): Keratin type II cytoskeletal 1 tail
16 ARID1Boncoprotein170.82422.965ARID (PF01388, IPR001606, SM00501): ARID/BRIGHT DNA binding domain
DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908)
Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region
Presenilin (PF01080, IPR001108): Presenilin
DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052)
DUF2235 (PF09994, IPR018712): Uncharacterized alpha/beta hydrolase domain (DUF2235)
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
BAF250_C (PF12031, IPR021906): SWI/SNF-like complex subunit BAF250/Osa
Spt20 (PF12090, IPR021950): Spt20 family
17 ASAP1interactor100.66710.176ArfGap (PF01412, IPR001164, SM00105): Putative GTPase activating protein for Arf
PH (PF00169, IPR001849, SM00233): PH domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404)
BAR_3 (PF16746): BAR domain of APPL family
18 ASAP2interactor70.5716.249ArfGap (PF01412, IPR001164, SM00105): Putative GTPase activating protein for Arf
PH (PF00169, IPR001849, SM00233): PH domain
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404)
SH3_9 (PF14604, IPR001452): Variant SH3 domain
BAR_3 (PF16746): BAR domain of APPL family
19 ATAD3Ainteractor60.26725.040AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
DUF3523 (PF12037, IPR021911): Domain of unknown function (DUF3523)
20 ATP5A1protein found in more fusions130.40982.828ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain
ATP-synt_ab_C (PF00306, IPR000793): ATP synthase alpha/beta chain, C terminal domain
ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain
21 ATXN2interactor150.343107.220LsmAD (PF06741, IPR009604): LsmAD domain
PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region
DUF3446 (PF11928, IPR021849): Domain of unknown function (DUF3446)
Spt20 (PF12090, IPR021950): Spt20 family
SM-ATX (PF14438, IPR025852): Ataxin 2 SM domain
22 BAZ1Binteractor70.7147.813D5_N (PF08706, IPR014818, SM00885): D5 N terminal like
DDT (PF02791, IPR004022, SM00571): DDT domain
DUF106 (PF01956, IPR002809): Integral membrane protein DUF106
Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
PHD (PF00628, IPR019787, SM00249): PHD-finger
YL1 (PF05764, IPR008895): YL1 nuclear protein
DDRGK (PF09756, IPR019153, SM01128): DDRGK domain
WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
DUF3635 (PF12330, IPR024604): Domain of unknown function (DUF3635)
Prok-RING_1 (PF14446): Prokaryotic RING finger family 1
FAM176 (PF14851): FAM176 family
WHIM1 (PF15612, IPR028942): WSTF, HB1, Itc1p, MBD9 motif 1
WSD (PF15613, IPR028941): Williams-Beuren syndrome DDT (WSD), D-TOX E motif
23 BCAR1oncoprotein160.52547.093Serine_rich (PF08824, IPR014928): Serine rich protein interaction domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
DUF3513 (PF12026, IPR021901): Domain of unknown function (DUF3513)
Caskin1-CID (PF16600): Caskin1 CASK-interaction domain
24 BCL7Asuppressor130.9366.212BCL_N (PF04714, IPR006804): BCL7, N-terminal conserver region
DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754)
RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6
UPF0561 (PF10573, IPR018888): Uncharacterised protein family UPF0561
25 BCL7Bsuppressor130.71855.778BCL_N (PF04714, IPR006804): BCL7, N-terminal conserver region
26 BCL7Csuppressor140.9890.133BCL_N (PF04714, IPR006804): BCL7, N-terminal conserver region
27 BIRC2oncoprotein90.6075.292BIR (PF00653, IPR001370, SM00238): Inhibitor of Apoptosis domain
CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
28 BLNKsuppressor70.6193.919SH2 (PF00017, IPR000980, SM00252): SH2 domain
29 BMI1oncoprotein200.310198.318zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
30 BPTFinteractor100Arc_PepC_II (PF06847, IPR009655): Archaeal Peptidase A24 C-terminus Type II
CobT (PF06213, IPR006538): Cobalamin biosynthesis protein CobT
DDT (PF02791, IPR004022, SM00571): DDT domain
DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764)
GRP (PF07172, IPR010800): Glycine rich protein family
OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain
PHD (PF00628, IPR019787, SM00249): PHD-finger
SDA1 (PF05285, IPR007949): SDA1
Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP)
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
WHIM1 (PF15612, IPR028942): WSTF, HB1, Itc1p, MBD9 motif 1
WSD (PF15613, IPR028941): Williams-Beuren syndrome DDT (WSD), D-TOX E motif
CCSAP (PF15748, IPR029774): Centriole, cilia and spindle-associated
PNISR (PF15996, IPR031937): Arginine/serine-rich protein PNISR
31 BRCA1suppressor290.185506.850BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT
32 CAPZA2interactor200.242157.901F-actin_cap_A (PF01267, IPR002189): F-actin capping protein alpha subunit
33 CAPZBinteractor150.257191.770Cytochrom_B562 (PF07361, IPR009155): Cytochrome b562
F_actin_cap_B (PF01115, IPR001698): F-actin capping protein, beta subunit
34 CARMIL1interactor40.6671.750LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
IL34 (PF15036, IPR020415): Interleukin 34
CARMIL_C (PF16000, IPR031943): CARMIL C-terminus
35 CASKIN2interactor100SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
SH3_2 (PF07653, IPR011511): Variant SH3 domain
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
Caskin1-CID (PF16600): Caskin1 CASK-interaction domain
Caskin-tail (PF16632, IPR032117): C-terminal region of Caskin
Caskin-Pro-rich (PF16907): Proline rich region of Caskin proteins
36 CBLsuppressor390.272376.764Cbl_N (PF02262, IPR003153): CBL proto-oncogene N-terminal domain 1
Cbl_N2 (PF02761, IPR014741): CBL proto-oncogene N-terminus, EF hand-like domain
Cbl_N3 (PF02762, IPR014742): CBL proto-oncogene N-terminus, SH2-like domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain
37 CBLBoncoprotein200.45646.131Cbl_N (PF02262, IPR003153): CBL proto-oncogene N-terminal domain 1
Cbl_N2 (PF02761, IPR014741): CBL proto-oncogene N-terminus, EF hand-like domain
Cbl_N3 (PF02762, IPR014742): CBL proto-oncogene N-terminus, SH2-like domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
PRIMA1 (PF16101): Proline-rich membrane anchor 1
38 CD2interactor50.6001.279C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain
Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
EphA2_TM (PF14575, IPR027936): Ephrin type-A receptor 2 transmembrane domain
39 CD2APprotein found in more fusions370.141551.565SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
betaPIX_CC (PF16523, IPR032409): betaPIX coiled coil
40 CDAoncoprotein21.0000dCMP_cyt_deam_1 (PF00383, IPR002125): Cytidine and deoxycytidylate deaminase zinc-binding region
dCMP_cyt_deam_2 (PF08211, IPR013171): Cytidine and deoxycytidylate deaminase zinc-binding region
41 CDC16interactor120.43976.268Dynein_light (PF01221, IPR001372): Dynein light chain type 1
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_17 (PF13431): Tetratricopeptide repeat
TPR_16 (PF13432): Tetratricopeptide repeat
SRP_TPR_like (PF17004, IPR031545): Putative TPR-like repeat
42 CDC23interactor120.52764.056ANAPC8 (PF04049, IPR007192): Anaphase promoting complex subunit 8 / Cdc23
DUF772 (PF05598, IPR008490): Transposase domain (DUF772)
Menin (PF05053, IPR007747): Menin
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
TPR_6 (PF13174, IPR019734): Tetratricopeptide repeat
TPR_7 (PF13176, IPR019734): Tetratricopeptide repeat
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_14 (PF13428): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
43 CDC27oncoprotein100.69442.410TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_12 (PF13424): Tetratricopeptide repeat
44 CDK16oncoprotein30.6677.138Pkinase (PF00069, IPR000719): Protein kinase domain
45 CIZ1suppressor3037.754Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP)
zf-U1 (PF06220, IPR013085, SM00451): U1 zinc finger
zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding
AAA_23 (PF13476): AAA domain
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
FAM163 (PF15069, IPR029379): FAM163 family
Zf_RING (PF16744, IPR031946): KIAA1045 RING finger
46 CKAP4protein found in more fusions100.50012.464DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180)
FPP (PF05911, IPR008587): Filament-like plant protein, long coiled-coil
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
47 CLTConcoprotein250.227303.900Clathrin-link (PF09268, IPR015348): Clathrin, heavy-chain linker
Clathrin_propel (PF01394, IPR022365): Clathrin propeller repeat
Clathrin (PF00637, IPR000547, SM00299): Region in Clathrin and VPS
Clathrin_H_link (PF13838): Clathrin-H-link
48 CRKoncoprotein240.391140.213SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_2 (PF07653, IPR011511): Variant SH3 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
49 CSNK1A1suppressor120.36491.786Pkinase (PF00069, IPR000719): Protein kinase domain
50 CSTF2interactor90.25047.069RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
CSTF_C (PF14304, IPR026896): Transcription termination and cleavage factor C-terminal
CSTF2_hinge (PF14327, IPR025742): Hinge domain of cleavage stimulation factor subunit 2
51 CTSBoncoprotein40.33322.243Peptidase_C1 (PF00112, IPR000668, SM00645): Papain family cysteine protease
Propeptide_C1 (PF08127, IPR012599): Peptidase family C1 propeptide
52 CUL3protein found in more fusions490.1681492.802Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
53 CYGBsuppressor100Globin (PF00042, IPR000971): Globin
54 DAB1interactor21.0000PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID)
55 DAB2suppressor140.30852.753PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID)
zf-C2H2_assoc3 (PF16637): Putative zinc-finger between two C2H2 zinc-fingers on Patz
56 DAG1interactor60.8001.469DAG1 (PF05454, IPR008465): Dystroglycan (Dystrophin-associated glycoprotein 1)
57 DDNinteractor100Dendrin (PF15498, IPR026500): Nephrin and CD2AP-binding protein, Dendrin
ACTH_assoc (PF16102, IPR032246): ACTH-associated domain
58 DDX17protein found in more fusions150.52761.241CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Ferritin (PF00210, IPR008331): Ferritin-like domain
GRP (PF07172, IPR010800): Glycine rich protein family
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
59 DDX28interactor30.3335.047DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
60 DNM1interactor100.50016.094Dynamin_M (PF01031, IPR000375): Dynamin central region
GED (PF02212, IPR003130, SM00302): Dynamin GTPase effector domain
PH (PF00169, IPR001849, SM00233): PH domain
Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family
61 DNM2interactor110.52714.970Dynamin_M (PF01031, IPR000375): Dynamin central region
GED (PF02212, IPR003130, SM00302): Dynamin GTPase effector domain
PH (PF00169, IPR001849, SM00233): PH domain
Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family
62 DNMT1suppressor60.20046.106BAH (PF01426, IPR001025, SM00439): BAH domain
DMAP_binding (PF06464, IPR010506, SM01137): DMAP1-binding Domain
DNA_methylase (PF00145, IPR001525): C-5 cytosine-specific DNA methylase
zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain
DNMT1-RFD (PF12047, IPR022702): Cytosine specific DNA methyltransferase replication foci domain
63 DPF2interactor190.70843.400PHD (PF00628, IPR019787, SM00249): PHD-finger
zf-C2H2_4 (PF13894): C2H2-type zinc finger
Requiem_N (PF14051, IPR025750): N-terminal domain of DPF2/REQ.
PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
Zf_RING (PF16744, IPR031946): KIAA1045 RING finger
64 DPF3interactor150.9242.181PHD (PF00628, IPR019787, SM00249): PHD-finger
zf-C2H2_4 (PF13894): C2H2-type zinc finger
Requiem_N (PF14051, IPR025750): N-terminal domain of DPF2/REQ.
Lar_restr_allev (PF14354): Restriction alleviation protein Lar
65 EGFRoncoprotein430.221693.697Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT)
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
66 ELAVL1oncoprotein640.0992906.525RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
67 ELMSAN1interactor31.0000ELM2 (PF01448, IPR000949): ELM2 domain
FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid)
Ndc1_Nup (PF09531, IPR019049): Nucleoporin protein Ndc1-Nup
zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
68 ENO1oncoprotein180.196249.067Enolase_C (PF00113, IPR020810): Enolase, C-terminal TIM barrel domain
Enolase_N (PF03952, IPR020811): Enolase, N-terminal domain
69 ERC1oncoprotein70.23846.465RBD-FIP (PF09457, IPR019018): FIP domain
BLOC1_2 (PF10046, IPR019269): Biogenesis of lysosome-related organelles complex-1 subunit 2
Cast (PF10174, IPR019323): RIM-binding protein of the cytomatrix active zone
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
70 FAM83Ginteractor40.5001.468DUF1669 (PF07894, IPR012461): Protein of unknown function (DUF1669)
Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP)
71 FAPinteractor100DPPIV_N (PF00930, IPR002469): Dipeptidyl peptidase IV (DPP IV) N-terminal region
Peptidase_S9 (PF00326, IPR001375): Prolyl oligopeptidase family
72 FBXO25suppressor70.33337.775Elongin_A (PF06881, IPR010684): RNA polymerase II transcription factor SIII (Elongin) subunit A
73 FGRoncoprotein60.5333.223Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
74 FRS3suppressor80.47646.852IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type)
75 FYNoncoprotein200.29879.802Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
76 GAS2L1interactor21.0000CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
GAS2 (PF02187, IPR003108, SM00243): Growth-Arrest-Specific Protein 2 Domain
SPX (PF03105, IPR004331): SPX domain
77 GRB2oncoprotein630.1501825.650SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
DUF5093 (PF17011, IPR031533): Domain of unknown function (DUF5093)
78 GTSE1interactor100.46715.943GTSE1_N (PF15259, IPR032768): G-2 and S-phase expressed 1
79 HCKoncoprotein130.38583.251Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
80 HGSinteractor160.35881.283FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
VHS (PF00790, IPR002014, SM00288): VHS domain
EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region
Hrs_helical (PF12210, IPR024641): Hepatocyte growth factor-regulated tyrosine kinase substrate
PIEZO (PF15917, IPR031805): Piezo
81 HIP1Rinteractor70.52412.837ANTH (PF07651, IPR011417): ANTH domain
ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
Fez1 (PF06818): Fez1
Laminin_II (PF06009, IPR010307): Laminin Domain II
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
I_LWEQ (PF01608, IPR002558, SM00307): I/LWEQ domain
DUF2968 (PF11180, IPR021350): Protein of unknown function (DUF2968)
DUF4140 (PF13600, IPR025554): N-terminal domain of unknown function (DUF4140)
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
82 HNRNPCprotein found in more fusions220.348226.873APG6 (PF04111, IPR007243): Autophagy protein Apg6
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SURF2 (PF05477, IPR008833): Surfeit locus protein 2 (SURF2)
83 HNRNPKoncoprotein250.319284.234ROKNT (PF08067, IPR012987): ROKNT (NUC014) domain
KH_1 (PF00013, IPR004088, SM00322): KH domain
84 HRASoncoprotein90.38920.878Ras (PF00071, IPR001806, SM00173): Ras family
85 IMPDH1interactor30.6671.106IMPDH (PF00478, IPR001093): IMP dehydrogenase / GMP reductase domain
86 IMPDH2protein found in more fusions100.361114.869IMPDH (PF00478, IPR001093): IMP dehydrogenase / GMP reductase domain
87 INPP5Dinteractor120.37992.019Exo_endo_phos (PF03372, IPR005135): Endonuclease/Exonuclease/phosphatase family
SH2 (PF00017, IPR000980, SM00252): SH2 domain
88 INPPL1oncoprotein130.64120.071Exo_endo_phos (PF03372, IPR005135): Endonuclease/Exonuclease/phosphatase family
SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
SH2 (PF00017, IPR000980, SM00252): SH2 domain
89 IRF2BP1interactor40.333210.082zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
IRF-2BP1_2 (PF11261, IPR022750): Interferon regulatory factor 2-binding protein zinc finger
90 IRF2BP2oncoprotein30.6671.106zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
IRF-2BP1_2 (PF11261, IPR022750): Interferon regulatory factor 2-binding protein zinc finger
DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729)
Bd3614_N (PF14442, IPR025854): Bd3614-like deaminase N-terminal
91 ITSN1interactor220.210175.795C2 (PF00168, IPR000008, SM00239): C2 domain
VIT1 (PF01988, IPR008217): VIT family
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
FmdE (PF02663, IPR003814): FmdE, Molybdenum formylmethanofuran dehydrogenase operon
GSH_synthase (PF03199, IPR004887): Eukaryotic glutathione synthase
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand
DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915)
SH3_9 (PF14604, IPR001452): Variant SH3 domain
DUF4748 (PF15932, IPR031833): Domain of unknown function (DUF4748)
INTAP (PF16617): Intersectin and clathrin adaptor AP2 binding region
PH_13 (PF16652, IPR001849): Pleckstrin homology domain
92 ITSN2protein found in more fusions160.28652.624C2 (PF00168, IPR000008, SM00239): C2 domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
SH3_2 (PF07653, IPR011511): Variant SH3 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
SH3_9 (PF14604, IPR001452): Variant SH3 domain
MRP-S26 (PF14943, IPR026140): Mitochondrial ribosome subunit S26
VIR_N (PF15912, IPR031801): Virilizer, N-terminal
PH_13 (PF16652, IPR001849): Pleckstrin homology domain
93 KATNA1interactor30.33311.467AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
ABC_tran (PF00005, IPR003439): ABC transporter
Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain
TPR_8 (PF13181, IPR019734): Tetratricopeptide repeat
AAA_22 (PF13401, IPR003593): AAA domain
94 KATNB1interactor40.33320.349WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
Katanin_con80 (PF13925, IPR028021): con80 domain of Katanin
95 KCTD10interactor60.33325.113BTB_2 (PF02214, IPR003131): BTB/POZ domain
96 KCTD3interactor203.941BTB_2 (PF02214, IPR003131): BTB/POZ domain
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
97 KHDRBS1protein found in more fusions280.208484.918KH_1 (PF00013, IPR004088, SM00322): KH domain
Qua1 (PF16274, IPR032571): Qua1 domain
Sam68-YY (PF16568, IPR032335): Tyrosine-rich domain of Sam68
98 KIAA1522interactor100OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain
NHS (PF15273, IPR024845): NHS-like
99 KIF23interactor120.28854.560DUF730 (PF05325, IPR007989): Protein of unknown function (DUF730)
Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
MKLP1_Arf_bdg (PF16540, IPR032384): Arf6-interacting domain of mitotic kinesin-like protein 1
100 KIToncoprotein110.6367.362ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
101 KLF13interactor21.0000zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
102 KPNA1interactor70.61917.176Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
IBB (PF01749, IPR002652): Importin beta binding domain
Arm_3 (PF16186, IPR032413): Atypical Arm repeat
103 KYNUinteractor40.16713.710Aminotran_5 (PF00266, IPR000192): Aminotransferase class-V
CaKB (PF03185, IPR003930): Calcium-activated potassium channel, beta subunit
104 LCKoncoprotein170.28359.981Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
105 LEMD2interactor100LEM (PF03020, IPR003887, SM00540): LEM domain
MSC (PF09402, IPR018996): Man1-Src1p-C-terminal domain
106 LIMCH1interactor70.476106.483LIM (PF00412, IPR001781, SM00132): LIM domain
MAS20 (PF02064, IPR002056): MAS20 protein import receptor
DUF3435 (PF11917, IPR021842): Protein of unknown function (DUF3435)
DUF4757 (PF15949, IPR031865): Domain of unknown function (DUF4757)
107 LOXsuppressor40.6670.750Lysyl_oxidase (PF01186, IPR001695): Lysyl oxidase
108 LYNoncoprotein190.320250.479Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
109 MAP3K4suppressor40.6671.105CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
Pkinase (PF00069, IPR000719): Protein kinase domain
PLU-1 (PF08429, IPR013637): PLU-1-like protein
Radial_spoke_3 (PF06098, IPR009290): Radial spoke protein 3
DUF3682 (PF12446, IPR022152): Protein of unknown function (DUF3682)
DUF3958 (PF13125, IPR025014): Protein of unknown function (DUF3958)
110 MAP4oncoprotein60.4675.325SdiA-regulated (PF06977, IPR009722): SdiA-regulated
Tubulin-binding (PF00418, IPR001084): Tau and MAP protein, tubulin-binding repeat
DUF3275 (PF11679, IPR021693): Protein of unknown function (DUF3275)
111 MAP7interactor100Asp-B-Hydro_N (PF05279, IPR007943): Aspartyl beta-hydroxylase N-terminal region
MAP7 (PF05672, IPR008604): MAP7 (E-MAP-115) family
Spore_coat_CotO (PF14153, IPR025439): Spore coat protein CotO
PH_5 (PF15405): Pleckstrin homology domain
112 MAP7D3interactor2021.290DUF572 (PF04502, IPR007590): Family of unknown function (DUF572)
MAP7 (PF05672, IPR008604): MAP7 (E-MAP-115) family
Sec62 (PF03839, IPR004728): Translocation protein Sec62
Nop25 (PF09805, IPR019186): Nucleolar protein 12 (25kDa)
ARGLU (PF15346): Arginine and glutamate-rich 1
113 MAP9interactor202.767LAP1C (PF05609, IPR008662): Lamina-associated polypeptide 1C (LAP1C)
Sec62 (PF03839, IPR004728): Translocation protein Sec62
DUF4207 (PF13904): Domain of unknown function (DUF4207)
114 MCM5oncoprotein90.55617.256MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
115 MDC1suppressor190.298238.484FHA (PF00498, IPR000253, SM00240): FHA domain
DUF3274 (PF11678, IPR021692): Protein of unknown function (DUF3274)
Yop-YscD_cpl (PF16697, IPR032030): Inner membrane component of T3SS, cytoplasmic domain
RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain
116 METoncoprotein90.7782.309Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
PSI (PF01437, IPR002165, SM00423): Plexin repeat
Sema (PF01403, IPR001627, SM00630): Sema domain
TIG (PF01833, IPR002909): IPT/TIG domain
117 MICALL1interactor100CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
LIM (PF00412, IPR001781, SM00132): LIM domain
DUF3585 (PF12130, IPR022735): Protein of unknown function (DUF3585)
FAM70 (PF14967, IPR028014): FAM70 protein
118 MOV10interactor330.174679.767AAA_12 (PF13087): AAA domain
AAA_30 (PF13604): AAA domain
119 MVB12Ainteractor40.8330.713DUF2464 (PF10240, IPR018798): Multivesicular body subunit 12
120 MYConcoprotein320.181868.626HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain
Myc_N (PF01056, IPR012682): Myc amino-terminal region
121 NOTCH2NLinteractor90.139138.965EGF (PF00008, IPR000742, SM00181): EGF-like domain
EGF_alliinase (PF04863, IPR006947): Alliinase EGF-like domain
EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
122 NPHS1interactor50.6671.286C2-set_2 (PF08205, IPR013162): CD80-like C2-set immunoglobulin domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
DUF4643 (PF15485, IPR028004): Domain of unknown function (DUF4643)
123 NPHS2interactor31.0000P_C (PF06640, IPR010588): P protein C-terminus
Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family
124 NPLOC4interactor110.45517.735NPL4 (PF05021, IPR007717): NPL4 family
zf-NPL4 (PF05020, IPR007716): NPL4 family, putative zinc binding region
UN_NPL4 (PF11543, IPR024682): Nuclear pore localisation protein NPL4
125 NTRK1oncoprotein910.0864965.684I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
126 NUDCD2interactor21.0000CS (PF04969, IPR007052): CS domain
DUF3110 (PF11360, IPR021503): Protein of unknown function (DUF3110)
127 NUP153protein found in more fusions140.295113.093Nup153 (PF08604, IPR013913): Nucleoporin Nup153-like
Nup_retrotrp_bd (PF10599, IPR018892): Retro-transposon transporting motif
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
Nucleoporin_FG (PF13634, IPR025574): Nucleoporin FG repeat region
128 NUP50interactor90.55636.212NUP50 (PF08911, IPR015007): NUP50 (Nucleoporin 50 kDa)
Ran_BP1 (PF00638, IPR000156, SM00160): RanBP1 domain
129 NXF1interactor390.1211087.058NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain
Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding
TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain
LRR_8 (PF13855, IPR001611): Leucine rich repeat
130 PABPC1oncoprotein160.32481.209RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain
YflT (PF11181, IPR025889): Heat induced stress protein YflT
131 PABPC4interactor120.43968.250ApbA_C (PF08546, IPR013752): Ketopantoate reductase PanE/ApbA C terminal
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain
HHV-5_US34A (PF17087, IPR031384): Herpesvirus US34A protein family
132 PAK1oncoprotein90.39313.215PBD (PF00786, IPR000095, SM00285): P21-Rho-binding domain
Pkinase (PF00069, IPR000719): Protein kinase domain
133 PAK2protein found in more fusions100.44420.012PBD (PF00786, IPR000095, SM00285): P21-Rho-binding domain
Pkinase (PF00069, IPR000719): Protein kinase domain
134 PALMDinteractor21.0000Paralemmin (PF03285, IPR004965): Paralemmin
135 PCM1oncoprotein90.167105.603FliD_N (PF02465, IPR003481): Flagellar hook-associated protein 2 N-terminus
FUSC (PF04632, IPR006726): Fusaric acid resistance protein family
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
NPV_P10 (PF05531, IPR008702): Nucleopolyhedrovirus P10 protein
Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family
RseA_C (PF03873, IPR005573): Anti sigma-E protein RseA, C-terminal domain
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
V_ATPase_I (PF01496, IPR002490): V-type ATPase 116kDa subunit family
AAA_23 (PF13476): AAA domain
zf-C4pol (PF14260, IPR025687): C4-type zinc-finger of DNA polymerase delta
PCM1_C (PF15717, IPR031446): Pericentriolar material 1 C terminus
DUF4829 (PF16111, IPR032256): Domain of unknown function (DUF4829)
136 PDCD6oncoprotein110.24426.535EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
137 PDCD6IPinteractor190.35383.483BRO1 (PF03097, IPR004328, SM01041): BRO1-like domain
MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
ALIX_LYPXL_bnd (PF13949, IPR025304): ALIX V-shaped domain binding to HIV
138 PDGFRBoncoprotein110.7335.996I-set (PF07679, IPR013098): Immunoglobulin I-set domain
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
Ig_3 (PF13927): Immunoglobulin domain
TonB_N (PF16031): TonB N-terminal region
139 PHACTR4suppressor40.6670.471RPEL (PF02755, IPR004018, SM00707): RPEL repeat
140 PHLDB1interactor201.106DUF501 (PF04417, IPR007511): Protein of unknown function (DUF501)
FHA (PF00498, IPR000253, SM00240): FHA domain
PH (PF00169, IPR001849, SM00233): PH domain
CENP-Q (PF13094, IPR025212): CENP-Q, a CENPA-CAD centromere complex subunit
WD40_alt (PF14077, IPR026987): Alternative WD40 repeat motif
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
141 PHLDB2interactor60.5337.298DUF572 (PF04502, IPR007590): Family of unknown function (DUF572)
MAP7 (PF05672, IPR008604): MAP7 (E-MAP-115) family
PH (PF00169, IPR001849, SM00233): PH domain
Synaptobrevin (PF00957, IPR001388): Synaptobrevin
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
MRP-S26 (PF14943, IPR026140): Mitochondrial ribosome subunit S26
DUF4574 (PF15141, IPR027896): Domain of unknown function (DUF4574)
142 PIK3R1oncoprotein300.330338.503RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_2 (PF07653, IPR011511): Variant SH3 domain
PI3K_P85_iSH2 (PF16454, IPR032498): Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain
143 PKP3interactor50.50051.679Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
DUF383 (PF04063, IPR007205): Domain of unknown function (DUF383)
144 PLEKHA5protein found in more fusions40.6670.263PH (PF00169, IPR001849, SM00233): PH domain
WW (PF00397, IPR001202, SM00456): WW domain
MKLP1_Arf_bdg (PF16540, IPR032384): Arf6-interacting domain of mitotic kinesin-like protein 1
145 PNMA5interactor40.6670.833PNMA (PF14893, IPR026523): PNMA
146 POM121interactor30.33326.555Ice_nucleation (PF00818, IPR000258): Ice nucleation protein repeat
Nucleoporin_FG (PF13634, IPR025574): Nucleoporin FG repeat region
POM121 (PF15229): POM121 family
147 PPFIBP1oncoprotein80.4296.744DUF16 (PF01519, IPR002862): Protein of unknown function DUF16
DUF342 (PF03961, IPR005646): Protein of unknown function (DUF342)
SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain
XkdW (PF09636, IPR019094): XkdW protein
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
DUF3837 (PF12939, IPR024212): Domain of unknown function (DUF3837)
148 PRC1interactor30.6671.200VIT1 (PF01988, IPR008217): VIT family
MAP65_ASE1 (PF03999, IPR007145): Microtubule associated protein (MAP65/ASE1 family)
149 PRRC2Ainteractor90.36132.792BAT2_N (PF07001, IPR009738): BAT2 N-terminus
MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
150 PSIP1oncoprotein21.0000AT_hook (PF02178, IPR017956, SM00384): AT hook motif
BEX (PF04538, IPR021156): Brain expressed X-linked like family
DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510)
PGA2 (PF07543, IPR011431): Protein trafficking PGA2
PWWP (PF00855, IPR000313, SM00293): PWWP domain
LEDGF (PF11467, IPR021567): Lens epithelium-derived growth factor (LEDGF)
TERB2 (PF15101, IPR028065): Telomere-associated protein TERB2
151 PSMA3interactor110.40093.344Proteasome (PF00227, IPR001353): Proteasome subunit
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
152 PSRC1interactor100GTSE1_N (PF15259, IPR032768): G-2 and S-phase expressed 1
153 PTK2protein found in more fusions190.51054.961FERM_M (PF00373, IPR019748): FERM central domain
Focal_AT (PF03623, IPR005189): Focal adhesion targeting region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
UCMA (PF17085, IPR031386): Unique cartilage matrix associated protein
154 PTK2Binteractor140.53815.195FERM_M (PF00373, IPR019748): FERM central domain
Focal_AT (PF03623, IPR005189): Focal adhesion targeting region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
155 PTPN1suppressor70.61950.119Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase
156 QPRTinteractor60.30021.135QRPTase_C (PF01729, IPR002638): Quinolinate phosphoribosyl transferase, C-terminal domain
QRPTase_N (PF02749, IPR022412): Quinolinate phosphoribosyl transferase, N-terminal domain
157 RAB11Aoncoprotein50.6004.163Ras (PF00071, IPR001806, SM00173): Ras family
158 RAB5Aoncoprotein70.38112.410Ras (PF00071, IPR001806, SM00173): Ras family
159 RACGAP1interactor110.327249.760RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
Cep57_CLD (PF14073, IPR025913): Centrosome localisation domain of Cep57
160 RAF1oncoprotein170.22583.419Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
RBD (PF02196, IPR003116, SM00455): Raf-like Ras-binding domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
161 RAPH1oncoprotein21.0000PH (PF00169, IPR001849, SM00233): PH domain
RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain
BORG_CEP (PF14957, IPR029273): Cdc42 effector
FAM76 (PF16046, IPR032017): FAM76 protein
PRIMA1 (PF16101): Proline-rich membrane anchor 1
Caskin-Pro-rich (PF16907): Proline rich region of Caskin proteins
162 RASAL2suppressor40.6671.486C2 (PF00168, IPR000008, SM00239): C2 domain
FliD_N (PF02465, IPR003481): Flagellar hook-associated protein 2 N-terminus
PH (PF00169, IPR001849, SM00233): PH domain
RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase
DUF3498 (PF12004, IPR021887): Domain of unknown function (DUF3498)
163 RBBP5oncoprotein90.42925.235WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457)
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
164 RNF2interactor250.228422.917zf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
165 RNF34interactor202.767Cwf_Cwc_15 (PF04889, IPR006973): Cwf15/Cwc15 cell cycle control protein
FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger
SAP (PF02037, IPR003034, SM00513): SAP domain
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
166 RPA1suppressor280.245386.707Rep-A_N (PF04057, IPR007199): Replication factor-A protein 1, N-terminal domain
Rep_fac-A_C (PF08646, IPR013955): Replication factor-A C terminal domain
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
REPA_OB_2 (PF16900, IPR031657): Replication protein A OB domain
167 RPGRIP1Linteractor100.35668.547bZIP_1 (PF00170, IPR004827): bZIP transcription factor
C2 (PF00168, IPR000008, SM00239): C2 domain
DivIC (PF04977, IPR007060): Septum formation initiator
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
FtsL (PF04999, IPR011922): Cell division protein FtsL
T3SS_needle_F (PF09392, IPR021123): Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
C2-C2_1 (PF11618, IPR021656): First C2 domain of RPGR-interacting protein 1
BNIP2 (PF12496, IPR022181): Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
DUF4497 (PF14924): Protein of unknown function (DUF4497)
168 RPS6KA4interactor209.153Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
169 SAMD1interactor30.6670.609CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510)
Pox_Ag35 (PF03286, IPR004966): Pox virus Ag35 surface protein
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
PRIMA1 (PF16101): Proline-rich membrane anchor 1
170 SAMHD1protein found in more fusions80.28651.326HD (PF01966, IPR006674): HD domain
SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
171 SEC24Cinteractor120.288108.835Gelsolin (PF00626, IPR007123): Gelsolin repeat
Sec23_BS (PF08033, IPR012990): Sec23/Sec24 beta-sandwich domain
Sec23_helical (PF04815, IPR006900): Sec23/Sec24 helical domain
Sec23_trunk (PF04811, IPR006896): Sec23/Sec24 trunk domain
zf-Sec23_Sec24 (PF04810, IPR006895): Sec23/Sec24 zinc finger
172 SEC24Dinteractor40.6671.734Gelsolin (PF00626, IPR007123): Gelsolin repeat
Sec23_BS (PF08033, IPR012990): Sec23/Sec24 beta-sandwich domain
Sec23_helical (PF04815, IPR006900): Sec23/Sec24 helical domain
Sec23_trunk (PF04811, IPR006896): Sec23/Sec24 trunk domain
Transp_Tc5_C (PF04236, IPR007350): Tc5 transposase C-terminal domain
zf-Sec23_Sec24 (PF04810, IPR006895): Sec23/Sec24 zinc finger
173 SEPT10interactor70.66725.332Septin (PF00735, IPR000038): Septin
Atg14 (PF10186, IPR018791): Vacuolar sorting 38 and autophagy-related subunit 14
174 SEPT11interactor80.57180.697Septin (PF00735, IPR000038): Septin
DUF3080 (PF11279, IPR021431): Protein of unknown function (DUF3080)
175 SEPT2oncoprotein120.53035.746FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger
Septin (PF00735, IPR000038): Septin
176 SEPT6oncoprotein90.6947.677Septin (PF00735, IPR000038): Septin
DUF2959 (PF11172, IPR021342): Protein of unknown function (DUF2959)
177 SEPT7interactor140.41896.032Fez1 (PF06818): Fez1
Septin (PF00735, IPR000038): Septin
178 SEPT8interactor80.64310.607IMD (PF08397, IPR013606): IRSp53/MIM homology domain
Septin (PF00735, IPR000038): Septin
DUF3987 (PF13148, IPR025048): Protein of unknown function (DUF3987)
179 SEPT9oncoprotein80.67914.267Septin (PF00735, IPR000038): Septin
DUF3306 (PF11748, IPR021735): Protein of unknown function (DUF3306)
180 SERPINH1interactor80.42945.103Serpin (PF00079, IPR023796, SM00093): Serpin (serine protease inhibitor)
181 SH3BP2oncoprotein50.9000.257PH (PF00169, IPR001849, SM00233): PH domain
SH2 (PF00017, IPR000980, SM00252): SH2 domain
182 SH3D19interactor31.0000SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
TMEM171 (PF15471, IPR029173): Transmembrane protein family 171
183 SH3GL2oncoprotein130.42427.648BAR (PF03114, IPR004148, SM00721): BAR domain
SH3_2 (PF07653, IPR011511): Variant SH3 domain
184 SH3GL3interactor70.6675.396BAR (PF03114, IPR004148, SM00721): BAR domain
SH3_2 (PF07653, IPR011511): Variant SH3 domain
185 SH3GLB1suppressor60.40010.330BAR (PF03114, IPR004148, SM00721): BAR domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
186 SH3GLB2interactor21.0000BAR (PF03114, IPR004148, SM00721): BAR domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
187 SH3PXD2Binteractor30.6671.106PX (PF00787, IPR001683, SM00312): PX domain
SH3_2 (PF07653, IPR011511): Variant SH3 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
188 SHCBP1interactor40.8331.162Methyltransf_10 (PF05971, IPR010286): Protein of unknown function (DUF890)
DUF2408 (PF10303, IPR018810): Protein of unknown function (DUF2408)
Pectate_lyase_3 (PF12708, IPR024535): Pectate lyase superfamily protein
Beta_helix (PF13229): Right handed beta helix region
189 SHKBP1interactor30.6673.941BTB_2 (PF02214, IPR003131): BTB/POZ domain
190 SIRT1suppressor120.309273.135DUF592 (PF04574, IPR007654): Protein of unknown function (DUF592)
SIR2 (PF02146, IPR003000): Sir2 family
TPP_enzyme_M (PF00205, IPR012000): Thiamine pyrophosphate enzyme, central domain
191 SLAIN2interactor50.20045.222bZIP_1 (PF00170, IPR004827): bZIP transcription factor
SLAIN (PF15301, IPR026179): SLAIN motif-containing family
192 SMARCA2suppressor230.538207.342DUF1168 (PF06658, IPR009548): Protein of unknown function (DUF1168)
DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840)
HSA (PF07529, IPR014012, SM00573): HSA
QLQ (PF08880, IPR014978, SM00951): QLQ
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
YL1 (PF05764, IPR008895): YL1 nuclear protein
BRK (PF07533, IPR006576, SM00592): BRK domain
DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052)
EPL1 (PF10513, IPR019542): Enhancer of polycomb-like
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
SnAC (PF14619, IPR029295): Snf2-ATP coupling, chromatin remodelling complex
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
193 SMARCA4suppressor300.455365.001DUF1840 (PF08895, IPR014991): Domain of unknown function (DUF1840)
HSA (PF07529, IPR014012, SM00573): HSA
QLQ (PF08880, IPR014978, SM00951): QLQ
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
BRK (PF07533, IPR006576, SM00592): BRK domain
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
DUF4065 (PF13274, IPR025272): Protein of unknown function (DUF4065)
SnAC (PF14619, IPR029295): Snf2-ATP coupling, chromatin remodelling complex
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
194 SMARCAD1interactor160.367156.118CUE (PF02845, IPR003892, SM00546): CUE domain
Pox_D5 (PF03288, IPR004968): Poxvirus D5 protein-like
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
195 SMARCB1suppressor260.547145.912SNF5 (PF04855, IPR006939): SNF5 / SMARCB1 / INI1
196 SMARCC1suppressor350.415510.059SWIRM (PF04433, IPR007526): SWIRM domain
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
DUF2618 (PF10940, IPR021237): Protein of unknown function (DUF2618)
PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated
SWIRM-assoc_1 (PF16495, IPR032451): SWIRM-associated region 1
SWIRM-assoc_2 (PF16496, IPR032450): SWIRM-associated domain at the N-terminal
SWIRM-assoc_3 (PF16498, IPR032448): SWIRM-associated domain at the C-terminal
197 SMARCC2interactor340.371622.614GHMP_kinases_N (PF00288, IPR006204): GHMP kinases N terminal domain
SWIRM (PF04433, IPR007526): SWIRM domain
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
SWIRM-assoc_1 (PF16495, IPR032451): SWIRM-associated region 1
SWIRM-assoc_2 (PF16496, IPR032450): SWIRM-associated domain at the N-terminal
SWIRM-assoc_3 (PF16498, IPR032448): SWIRM-associated domain at the C-terminal
198 SMARCD1interactor270.430369.442ATP-synt_G (PF04718, IPR006808): Mitochondrial ATP synthase g subunit
DivIC (PF04977, IPR007060): Septum formation initiator
SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain
199 SMARCE1interactor250.493211.166DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
GCN5L1 (PF06320, IPR009395): GCN5-like protein 1 (GCN5L1)
Ndc1_Nup (PF09531, IPR019049): Nucleoporin protein Ndc1-Nup
HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
Ferlin_C (PF16165, IPR032362): Ferlin C-terminus
200 SOS1oncoprotein160.45837.073Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
PH (PF00169, IPR001849, SM00233): PH domain
RasGEF (PF00617, IPR001895, SM00147): RasGEF domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
RasGEF_N (PF00618, IPR000651, SM00229): RasGEF N-terminal motif
201 SPRY1interactor70.57149.248PAP1 (PF08601, IPR013910): Transcription factor PAP1
Sprouty (PF05210, IPR007875): Sprouty protein (Spry)
202 SPRY2suppressor150.30854.641KAR9 (PF08580, IPR013889): Yeast cortical protein KAR9
Sprouty (PF05210, IPR007875): Sprouty protein (Spry)
203 SRConcoprotein370.276334.552Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
204 SRGAP1interactor21.0000DASH_Dad3 (PF08656, IPR013965): DASH complex subunit Dad3
FCH (PF00611, IPR001060, SM00055): Fes/CIP4, and EFC/F-BAR homology domain
FlaC_arch (PF05377, IPR008039): Flagella accessory protein C (FlaC)
FTZ (PF03867, IPR005567): Fushi tarazu (FTZ), N-terminal region
IncA (PF04156, IPR007285): IncA protein
RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
Transposase_21 (PF02992, IPR004242): Transposase family tnp2
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
CREPT (PF16566, IPR032337): Cell-cycle alteration and expression-elevated protein in tumour
205 SRRM1interactor110.38276.020DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754)
ETRAMP (PF09716, IPR006389): Malarial early transcribed membrane protein (ETRAMP)
Hepatitis_core (PF00906, IPR002006): Hepatitis core antigen
MAP65_ASE1 (PF03999, IPR007145): Microtubule associated protein (MAP65/ASE1 family)
PWI (PF01480, IPR002483, SM00311): PWI domain
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
206 SRRM2interactor150.352315.674cwf21 (PF08312, IPR013170, SM01115): cwf21 domain
DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754)
Pap_E4 (PF02711, IPR003861): E4 protein
RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6
CTD (PF12815, IPR024945, SM01104): Spt5 C-terminal nonapeptide repeat binding Spt4
DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614)
207 SRSF7interactor80.39311.998RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
TP2 (PF01254, IPR000678): Nuclear transition protein 2
zf-CCHC (PF00098, IPR001878): Zinc knuckle
208 SS18oncoprotein200.749234.429SSXT (PF05030, IPR007726): SSXT protein (N-terminal region)
Rrn6 (PF10214, IPR019350): RNA polymerase I-specific transcription-initiation factor
209 STAP1interactor41.0000PH (PF00169, IPR001849, SM00233): PH domain
SH2 (PF00017, IPR000980, SM00252): SH2 domain
210 SYDE1oncoprotein100RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
211 SYNJ1interactor60.6003.919DUF1866 (PF08952, IPR015047, SM01165): Domain of unknown function (DUF1866)
Exo_endo_phos (PF03372, IPR005135): Endonuclease/Exonuclease/phosphatase family
Syja_N (PF02383, IPR002013): SacI homology domain
YppG (PF14179, IPR025555): YppG-like protein
212 SYNJ2interactor40.6670.447DUF1866 (PF08952, IPR015047, SM01165): Domain of unknown function (DUF1866)
Exo_endo_phos (PF03372, IPR005135): Endonuclease/Exonuclease/phosphatase family
Syja_N (PF02383, IPR002013): SacI homology domain
TSKS (PF15358, IPR028214): Testis-specific serine kinase substrate
213 SYNPOinteractor100.46721.422Calsarcin (PF05556, IPR008438): Calcineurin-binding protein (Calsarcin)
214 TAF6interactor70.476126.171CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
TAF6_C (PF07571, IPR011442): TAF6 C-terminal HEAT repeat domain
Spo0A_C (PF08769, IPR014879): Sporulation initiation factor Spo0A C terminal
TAF (PF02969, IPR004823, SM00803): TATA box binding protein associated factor (TAF)
215 TBL1Xprotein found in more fusions80.38121.899K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
LisH (PF08513, IPR013720, SM00667): LisH
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
LCE6A (PF15858, IPR031716): Late cornified envelope protein 6A family
216 TBL1XR1oncoprotein130.436115.032LisH (PF08513, IPR013720, SM00667): LisH
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
217 TGFBR1oncoprotein60.53310.978Activin_recp (PF01064, IPR000472): Activin types I and II receptor domain
Pkinase (PF00069, IPR000719): Protein kinase domain
TGF_beta_GS (PF08515, IPR003605, SM00467): Transforming growth factor beta type I GS-motif
218 TGFBR2suppressor60.6003.353ecTbetaR2 (PF08917, IPR015013): Transforming growth factor beta receptor 2 ectodomain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
219 TJP2oncoprotein30.6670.625PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
SH3_2 (PF07653, IPR011511): Variant SH3 domain
Guanylate_kin (PF00625, IPR008145, SM00072): Guanylate kinase
220 TNFRSF1Aoncoprotein160.43858.092Death (PF00531, IPR000488, SM00005): Death domain
TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region
221 TOP2Boncoprotein140.44091.854CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain
DASH_Spc19 (PF08287, IPR013251): Spc19
DNA_gyraseB (PF00204, IPR013506): DNA gyrase B
DTHCT (PF08070, IPR012542): DTHCT (NUC029) region
HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
Toprim (PF01751, IPR006171, SM00493): Toprim domain
Anophelin (PF10731, IPR018932): Thrombin inhibitor from mosquito
DNA_topoisoIV (PF00521, IPR002205, SM00434): DNA gyrase/topoisomerase IV, subunit A
PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
TOPRIM_C (PF16898, IPR031660): C-terminal associated domain of TOPRIM
222 TP53suppressor480.1491322.986DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
P53 (PF00870, IPR011615): P53 DNA-binding domain
P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
223 TP63suppressor90.32127.755Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
P53 (PF00870, IPR011615): P53 DNA-binding domain
P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
224 TP73suppressor80.66710.241P53 (PF00870, IPR011615): P53 DNA-binding domain
P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
225 TRAoncoprotein21.0000NA
226 TRADDinteractor51.0000Death (PF00531, IPR000488, SM00005): Death domain
TRADD_N (PF09034, IPR009095): TRADD, N-terminal domain
TPR_14 (PF13428): Tetratricopeptide repeat
227 TRAF1oncoprotein90.5718.607HypA (PF01155, IPR000688): Hydrogenase/urease nickel incorporation, metallochaperone, hypA
SlyX (PF04102, IPR007236): SlyX
TRAF_BIRC3_bd (PF16673, IPR032070): TNF receptor-associated factor BIRC3 binding domain
228 TRAF2interactor120.43665.192MATH (PF00917, IPR002083, SM00061): MATH domain
Sina (PF03145, IPR018121): Seven in absentia protein family
SlyX (PF04102, IPR007236): SlyX
zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger
TRAF_BIRC3_bd (PF16673, IPR032070): TNF receptor-associated factor BIRC3 binding domain
zf-C3HC4_5 (PF17121, IPR001841): Zinc finger, C3HC4 type (RING finger)
229 TSG101suppressor200.304120.853APG6 (PF04111, IPR007243): Autophagy protein Apg6
Laminin_II (PF06009, IPR010307): Laminin Domain II
UEV (PF05743, IPR008883): UEV domain
Vps23_core (PF09454, IPR017916): Vps23 core domain
230 TTC38interactor21.0000TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_14 (PF13428): Tetratricopeptide repeat
231 TUBGCP2interactor80.46425.473Spc97_Spc98 (PF04130, IPR007259): Spc97 / Spc98 family
zf-Tim10_DDP (PF02953, IPR004217): Tim10/DDP family zinc finger
232 TUBGCP3interactor80.39331.052Spc97_Spc98 (PF04130, IPR007259): Spc97 / Spc98 family
233 TUBGCP4interactor31.0000Spc97_Spc98 (PF04130, IPR007259): Spc97 / Spc98 family
234 UBCprotein found in more fusions400.224661.264ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
235 UBE2Iinteractor250.170641.759UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
236 UFD1Linteractor60.7334.517UFD1 (PF03152, IPR004854): Ubiquitin fusion degradation protein UFD1
237 UNKLinteractor100Mnd1 (PF03962, IPR005647): Mnd1 family
zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
238 UPF2interactor110.244114.890DDHD (PF02862, IPR004177, SM01127): DDHD domain
DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510)
MIF4G (PF02854, IPR003890, SM00543): MIF4G domain
Upf2 (PF04050, IPR007193): Up-frameshift suppressor 2
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
SUFU_C (PF12470, IPR024314): Suppressor of Fused Gli/Ci N terminal binding domain
239 VPS37Binteractor40.50054.427Mod_r (PF07200, IPR009851): Modifier of rudimentary (Mod(r)) protein
240 WASLinteractor110.43627.024Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
PBD (PF00786, IPR000095, SM00285): P21-Rho-binding domain
WH1 (PF00568, IPR000697, SM00461): WH1 domain
WH2 (PF02205, IPR003124, SM00246): WH2 motif
RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein
Caskin-Pro-rich (PF16907): Proline rich region of Caskin proteins
241 WIPF1interactor70.4767.724CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
GRP (PF07172, IPR010800): Glycine rich protein family
WH2 (PF02205, IPR003124, SM00246): WH2 motif
242 WIPF2interactor40.8330.297CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
WH2 (PF02205, IPR003124, SM00246): WH2 motif
CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance
Caskin-Pro-rich (PF16907): Proline rich region of Caskin proteins
243 WTAPoncoprotein21.0000DUF1043 (PF06295, IPR009386): Protein of unknown function (DUF1043)
SOSSC (PF15925, IPR031821): SOSS complex subunit C
Wtap (PF17098, IPR029732): WTAP/Mum2p family
244 XRN1interactor120.197162.244XRN_N (PF03159, IPR004859): XRN 5'-3' exonuclease N-terminus
245 ZBTB7Binteractor40.33310.977BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
GAGA (PF09237, IPR015318): GAGA factor
SMN (PF06003, IPR010304): Survival motor neuron protein (SMN)
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
246 ZFP36suppressor70.28673.647zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
247 ZNF219interactor21.0000Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zinc_ribbon_10 (PF10058, IPR019273): Predicted integral membrane zinc-ribbon metal-binding protein
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain
PRIMA1 (PF16101): Proline-rich membrane anchor 1

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