Find Fusion Network

Enter
Fusion ID:
Protein names:


Level of PPIs:
or Upload text file:
Update repository
Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins DPP7, FRMD4B (from a repository: Tue Jul 23 06:22:16 2019)
Examples

Cytoscape Web will replace the contents your graph
PPI Properties:

Click on nodes
or edges

Layout Tree
Circle
Radial
Force Directed
Preset
Export graph
PDF file
SVG file
SIF file
XML file
GraphML file

Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)12
The number (and %) of the onco-proteins3 (25.00 %)
The number (and %) of the tumor suppressors1 (8.33 %)
Total number of binary PPIs (saturation %)20 (30.30 %)
The number (and %) of affected PPIs10 (50.00 %)
The number of possible different fusions1
PPI diameter4
PPI radius2
The average degree of PPI3.333
Assortativity coefficient-0.5128
The network average Clustering coefficient0.372
The number (and %) of a zero Clustering coefficients5 (41.67 %)
The number (and %) of a zero Betweenness Centrality6 (50.00 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: DPP7,FRMD4B All fusions
Proteins found in more fusions

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 DPP7parental protein90.19467.400Peptidase_S28 (PF05577, IPR008758): Serine carboxypeptidase S28
2 FRMD4Bparental protein100FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain
FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
Med30 (PF11315, IPR021019): Mediator complex subunit 30
DUF3338 (PF11819, IPR021774): Domain of unknown function (DUF3338)
3 CSTBoncoprotein21.0000Cystatin (PF00031, IPR000010, SM00043): Cystatin domain
4 FBXO6interactor100FBA (PF04300, IPR007397): F-box associated region
F-box-like (PF12937, IPR001810): F-box-like
5 MYCBPinteractor100Pox_TAA1 (PF03295, IPR004975): Poxvirus trans-activator protein A1 C-terminal
TSC22 (PF01166, IPR000580): TSC-22/dip/bun family
6 PLCG1oncoprotein41.0000C2 (PF00168, IPR000008, SM00239): C2 domain
PH (PF00169, IPR001849, SM00233): PH domain
SH2 (PF00017, IPR000980, SM00252): SH2 domain
PI-PLC-X (PF00388, IPR000909, SM00148): Phosphatidylinositol-specific phospholipase C, X domain
PI-PLC-Y (PF00387, IPR001711, SM00149): Phosphatidylinositol-specific phospholipase C, Y domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
PH_12 (PF16457, IPR001849): Pleckstrin homology domain
7 RIC8Ainteractor50.70010.933PUL (PF08324, IPR013535): PUL domain
Ric8 (PF10165, IPR019318): Guanine nucleotide exchange factor synembryn
8 SARNPoncoprotein50.7004.600SAP (PF02037, IPR003034, SM00513): SAP domain
HTH_Tnp_IS630 (PF01710, IPR002622): Transposase
Prok-E2_A (PF14457, IPR032865): Prokaryotic E2 family A
9 SELENBP1suppressor100SBP56 (PF05694, IPR008826): 56kDa selenium binding protein (SBP56)
10 WDR61interactor50.70010.933WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
11 XPO1interactor40.16722.000CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
12 XRN1interactor206.133XRN_N (PF03159, IPR004859): XRN 5'-3' exonuclease N-terminus

B a c k    t o    T o p ⇑