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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins DPP7, FRMD4B (from a repository: Tue Jul 23 06:22:16 2019)

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)12
The number (and %) of the onco-proteins3 (25.00 %)
The number (and %) of the tumor suppressors1 (8.33 %)
Total number of binary PPIs (saturation %)20 (30.30 %)
The number (and %) of affected PPIs10 (50.00 %)
The number of possible different fusions1
PPI diameter4
PPI radius2
The average degree of PPI3.333
Assortativity coefficient-0.5128
The network average Clustering coefficient0.372
The number (and %) of a zero Clustering coefficients5 (41.67 %)
The number (and %) of a zero Betweenness Centrality6 (50.00 %)


List of the fusions

PPI for parental proteins: DPP7,FRMD4B All fusions
Proteins found in more fusions

List of active interactors

# Name Type Number of PPI (degree) Clustering
Domains (Pfam, InterPro, SMART): description
1 DPP7parental protein90.19467.400Peptidase_S28 (PF05577, IPR008758): Serine carboxypeptidase S28
2 FRMD4Bparental protein100FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain
FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
Med30 (PF11315, IPR021019): Mediator complex subunit 30
DUF3338 (PF11819, IPR021774): Domain of unknown function (DUF3338)
3 CSTBoncoprotein21.0000Cystatin (PF00031, IPR000010, SM00043): Cystatin domain
4 FBXO6interactor100FBA (PF04300, IPR007397): F-box associated region
F-box-like (PF12937, IPR001810): F-box-like
5 MYCBPinteractor100Pox_TAA1 (PF03295, IPR004975): Poxvirus trans-activator protein A1 C-terminal
TSC22 (PF01166, IPR000580): TSC-22/dip/bun family
6 PLCG1oncoprotein41.0000C2 (PF00168, IPR000008, SM00239): C2 domain
PH (PF00169, IPR001849, SM00233): PH domain
SH2 (PF00017, IPR000980, SM00252): SH2 domain
PI-PLC-X (PF00388, IPR000909, SM00148): Phosphatidylinositol-specific phospholipase C, X domain
PI-PLC-Y (PF00387, IPR001711, SM00149): Phosphatidylinositol-specific phospholipase C, Y domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
PH_12 (PF16457, IPR001849): Pleckstrin homology domain
7 RIC8Ainteractor50.70010.933PUL (PF08324, IPR013535): PUL domain
Ric8 (PF10165, IPR019318): Guanine nucleotide exchange factor synembryn
8 SARNPoncoprotein50.7004.600SAP (PF02037, IPR003034, SM00513): SAP domain
HTH_Tnp_IS630 (PF01710, IPR002622): Transposase
Prok-E2_A (PF14457, IPR032865): Prokaryotic E2 family A
9 SELENBP1suppressor100SBP56 (PF05694, IPR008826): 56kDa selenium binding protein (SBP56)
10 WDR61interactor50.70010.933WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
11 XPO1interactor40.16722.000CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
12 XRN1interactor206.133XRN_N (PF03159, IPR004859): XRN 5'-3' exonuclease N-terminus

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