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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins ZNF394, ZNF789 (from a repository: Thu Dec 8 02:18:50 2016)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)8
The number (and %) of the onco-proteins1 (12.50 %)
The number (and %) of the tumor suppressors1 (12.50 %)
Total number of binary PPIs (saturation %)12 (42.86 %)
The number (and %) of affected PPIs6 (50.00 %)
The number of possible different fusions0
PPI diameter2
PPI radiusinf
The average degree of PPI2.250
Assortativity coefficient-0.5000
The network average Clustering coefficient0.400
The number (and %) of a zero Clustering coefficients4 (50.00 %)
The number (and %) of a zero Betweenness Centrality7 (87.50 %)

ACTIVE INTERACTORS


List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 ZNF394parental protein60.20024.000zf-RING_7 (PF02591, IPR003743): C4-type zinc ribbon domain
KRAB (PF01352, IPR001909, SM00349): KRAB box
SCAN (PF02023, IPR003309, SM00431): SCAN domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
2 ZNF789interactor000ADK_lid (PF05191, IPR007862): Adenylate kinase, active site lid
KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_8 (PF15909, IPR031799): C2H2-type zinc ribbon
3 CCNDBP1suppressor100CheF-arch (PF04283, IPR007381): Chemotaxis signal transduction system protein F from archaea
GCIP (PF13324): Grap2 and cyclin-D-interacting
4 CLK2interactor200DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764)
Pkinase (PF00069, IPR000719): Protein kinase domain
zf-met (PF12874): Zinc-finger of C2H2 type
5 USP7oncoprotein200MATH (PF00917, IPR002083, SM00061): MATH domain
UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
USP7_ICP0_bdg (PF12436, IPR024729): ICP0-binding domain of Ubiquitin-specific protease 7
USP7_C2 (PF14533, IPR029346): Ubiquitin-specific protease C-terminal
6 ZNF397interactor31.0000SCAN (PF02023, IPR003309, SM00431): SCAN domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
7 ZSCAN20interactor31.0000SCAN (PF02023, IPR003309, SM00431): SCAN domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
Glyco_trans_1_2 (PF13524): Glycosyl transferases group 1
Myb_DNA-bind_4 (PF13837): Myb/SANT-like DNA-binding domain
zf-C2H2_11 (PF16622, IPR007087): zinc-finger C2H2-type
8 ZSCAN32interactor41.0000KRAB (PF01352, IPR001909, SM00349): KRAB box
SCAN (PF02023, IPR003309, SM00431): SCAN domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
Mu-like_Com (PF10122, IPR019294): Mu-like prophage protein Com
DUF3613 (PF12266, IPR022053): Protein of unknown function (DUF3613)
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
Myb_DNA-bind_4 (PF13837): Myb/SANT-like DNA-binding domain

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