1 |
GNB1 | parental protein | 80 | 0.055 | 7671.643 | Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat |
2 |
CASP7 | parental protein | 46 | 0.148 | 1831.568 | Peptidase_C14 (PF00656, IPR011600): Caspase domain PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
3 |
ABCE1 | interactor | 14 | 0.141 | 478.016 | ABC_tran (PF00005, IPR003439): ABC transporter Fer4 (PF00037, IPR001450): 4Fe-4S binding domain RLI (PF04068, IPR007209): Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain Fer4_7 (PF12838, IPR001450): 4Fe-4S dicluster domain AAA_29 (PF13555): P-loop containing region of AAA domain |
4 |
ADRA2A | interactor | 4 | 0.667 | 0.400 | 7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family) |
5 |
ADRB2 | interactor | 14 | 0.154 | 229.552 | 7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family) |
6 |
AFP | interactor | 2 | 0 | 67.786 | Serum_albumin (PF00273, IPR014760, SM00103): Serum albumin family |
7 |
AKT1 | oncoprotein | 12 | 0.291 | 168.837 | PH (PF00169, IPR001849, SM00233): PH domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
8 |
ARHGDIA | interactor | 13 | 0.227 | 199.153 | Rho_GDI (PF02115, IPR000406): RHO protein GDP dissociation inhibitor |
9 |
ARHGEF18 | interactor | 2 | 0 | 23.648 | PH (PF00169, IPR001849, SM00233): PH domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082) |
10 |
ARRB1 | interactor | 9 | 0.222 | 137.059 | Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain |
11 |
ATP6V1B1 | interactor | 2 | 0 | 8.609 | ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain DUF3533 (PF12051, IPR022703): Protein of unknown function (DUF3533) |
12 |
ATXN10 | interactor | 5 | 0.400 | 29.715 | RIH_assoc (PF08454, IPR013662): RyR and IP3R Homology associated Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain |
13 |
AVPR2 | interactor | 4 | 0.500 | 15.703 | 7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family) |
14 |
BAX | suppressor | 8 | 0.810 | 8.036 | Bcl-2 (PF00452, IPR026298): Apoptosis regulator proteins, Bcl-2 family |
15 |
BIRC2 | oncoprotein | 12 | 0.745 | 8.711 | BIR (PF00653, IPR001370, SM00238): Inhibitor of Apoptosis domain CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
16 |
BIRC3 | oncoprotein | 10 | 0.833 | 3.311 | BIR (PF00653, IPR001370, SM00238): Inhibitor of Apoptosis domain CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
17 |
BIRC5 | interactor | 9 | 0.643 | 67.802 | BIR (PF00653, IPR001370, SM00238): Inhibitor of Apoptosis domain |
18 |
BIRC6 | oncoprotein | 5 | 1.000 | 0 | BIR (PF00653, IPR001370, SM00238): Inhibitor of Apoptosis domain SlyX (PF04102, IPR007236): SlyX UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme BIRC6 (PF12356, IPR022103): Baculoviral IAP repeat-containing protein 6 ABC_tran_CTD (PF16326, IPR032524): ABC transporter C-terminal domain |
19 |
BIRC7 | interactor | 6 | 1.000 | 0 | BIR (PF00653, IPR001370, SM00238): Inhibitor of Apoptosis domain zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
20 |
BTK | suppressor | 5 | 0.500 | 3.749 | BTK (PF00779, IPR001562, SM00107): BTK motif PH (PF00169, IPR001849, SM00233): PH domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
21 |
CAPN1 | interactor | 13 | 0.487 | 165.437 | Calpain_III (PF01067, IPR022682, SM00720): Calpain large subunit, domain III Peptidase_C2 (PF00648, IPR001300, SM00230): Calpain family cysteine protease EF-hand_6 (PF13405, IPR002048): EF-hand domain EF-hand_8 (PF13833, IPR002048): EF-hand domain pair |
22 |
CASP10 | interactor | 12 | 0.745 | 9.763 | DED (PF01335, IPR001875, SM00031): Death effector domain Peptidase_C14 (PF00656, IPR011600): Caspase domain |
23 |
CASP2 | suppressor | 11 | 0.733 | 48.151 | CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain Peptidase_C14 (PF00656, IPR011600): Caspase domain |
24 |
CASP3 | interactor | 30 | 0.217 | 661.649 | Peptidase_C14 (PF00656, IPR011600): Caspase domain |
25 |
CASP8 | suppressor | 20 | 0.374 | 125.358 | DED (PF01335, IPR001875, SM00031): Death effector domain Peptidase_C14 (PF00656, IPR011600): Caspase domain |
26 |
CASP9 | oncoprotein | 15 | 0.524 | 64.085 | CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain Peptidase_C14 (PF00656, IPR011600): Caspase domain |
27 |
CCDC8 | interactor | 15 | 0.176 | 154.093 | Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal PNMA (PF14893, IPR026523): PNMA |
28 |
CCT2 | interactor | 12 | 0.258 | 137.459 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
29 |
CCT5 | interactor | 10 | 0.444 | 40.687 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
30 |
CEP128 | interactor | 4 | 0.500 | 2.754 | DUF1129 (PF06570, IPR009214): Protein of unknown function (DUF1129) DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) ERM (PF00769, IPR011259): Ezrin/radixin/moesin family Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein SpoOE-like (PF09388, IPR018540): Spo0E like sporulation regulatory protein DUF2968 (PF11180, IPR021350): Protein of unknown function (DUF2968) TraF_2 (PF13729, IPR032811): F plasmid transfer operon, TraF, protein GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200) DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404) HAUS6_N (PF14661, IPR028163): HAUS augmin-like complex subunit 6 N-terminus HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1 |
31 |
CLSPN | interactor | 3 | 0.333 | 4.136 | Cwf_Cwc_15 (PF04889, IPR006973): Cwf15/Cwc15 cell cycle control protein DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) NinG (PF05766, IPR008713): Bacteriophage Lambda NinG protein Presenilin (PF01080, IPR001108): Presenilin PTS_IIB (PF02302, IPR003501): PTS system, Lactose/Cellobiose specific IIB subunit XAP5 (PF04921, IPR007005): XAP5, circadian clock regulator Adaptin_binding (PF10199, IPR019341): Alpha and gamma adaptin binding protein p34 Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal |
32 |
CNDP2 | suppressor | 8 | 0.929 | 0.667 | Peptidase_M20 (PF01546, IPR002933): Peptidase family M20/M25/M40 |
33 |
COPS6 | interactor | 10 | 0.278 | 79.929 | DUF320 (PF03777, IPR005528): Small secreted domain (DUF320) JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function |
34 |
COX4I1 | interactor | 1 | 0 | 0 | COX4 (PF02936, IPR004203): Cytochrome c oxidase subunit IV |
35 |
CRYAB | oncoprotein | 8 | 0.952 | 0.333 | Crystallin (PF00525, IPR003090): Alpha crystallin A chain, N terminal HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family |
36 |
CTSA | interactor | 5 | 0.600 | 41.106 | Peptidase_S10 (PF00450, IPR001563): Serine carboxypeptidase |
37 |
CUL4A | protein found in more fusions | 9 | 0.250 | 65.491 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
38 |
CYFIP1 | interactor | 3 | 0.333 | 24.598 | DUF1394 (PF07159, IPR009828): Protein of unknown function (DUF1394) FragX_IP (PF05994, IPR008081): Cytoplasmic Fragile-X interacting family |
39 |
DFFA | suppressor | 4 | 0.500 | 23.714 | CIDE-N (PF02017, IPR003508): CIDE-N domain DFF-C (PF09033, IPR015121): DNA Fragmentation factor 45kDa, C terminal domain T2SSppdC (PF12528, IPR022204): Type II secretion prepilin peptidase dependent protein C SAPIS-gp6 (PF16722, IPR031999): Pathogenicity island protein gp6 in Staphylococcus |
40 |
DISC1 | interactor | 4 | 0.167 | 46.363 | HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper Mnd1 (PF03962, IPR005647): Mnd1 family TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein Tropomyosin (PF00261, IPR000533): Tropomyosin UVR (PF02151, IPR001943): UvrB/uvrC motif CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding |
41 |
EEF2 | interactor | 14 | 0.275 | 197.352 | EFG_C (PF00679, IPR000640, SM00838): Elongation factor G C-terminus EFG_IV (PF03764, IPR005517, SM00889): Elongation factor G, domain IV GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 EFG_II (PF14492, IPR009022): Elongation Factor G, domain II |
42 |
EIF4H | interactor | 6 | 0.600 | 67.060 | eIF-4B (PF06273, IPR010433): Plant specific eukaryotic initiation factor 4B RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
43 |
ELAVL1 | oncoprotein | 24 | 0.178 | 1009.831 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
44 |
EPHA7 | oncoprotein | 1 | 0 | 0 | EGF_2 (PF07974, IPR013111): EGF-like domain EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Ephrin_rec_like (PF07699, IPR011641): Putative ephrin-receptor like Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif) Ephrin_lbd (PF01404, IPR001090, SM00615): Ephrin receptor ligand binding domain EphA2_TM (PF14575, IPR027936): Ephrin type-A receptor 2 transmembrane domain |
45 |
ESR1 | suppressor | 21 | 0.168 | 515.976 | Oest_recep (PF02159, IPR001292): Oestrogen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal |
46 |
ESRRB | suppressor | 3 | 0 | 33.452 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
47 |
FBXW11 | interactor | 7 | 0.333 | 71.126 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain F-box-like (PF12937, IPR001810): F-box-like |
48 |
FYN | oncoprotein | 10 | 0.278 | 104.215 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
49 |
GBP2 | interactor | 8 | 0.786 | 8.002 | GBP (PF02263, IPR015894): Guanylate-binding protein, N-terminal domain GBP_C (PF02841, IPR003191): Guanylate-binding protein, C-terminal domain |
50 |
GINS2 | interactor | 9 | 0.667 | 14.589 | Sld5 (PF05916, IPR021151): GINS complex protein |
51 |
GLI1 | suppressor | 3 | 0.667 | 1.778 | zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain FOXP-CC (PF16159, IPR032354): FOXP coiled-coil domain |
52 |
GNA11 | oncoprotein | 6 | 0.400 | 18.351 | G-alpha (PF00503, IPR001019, SM00275): G-protein alpha subunit |
53 |
GNAI1 | oncoprotein | 13 | 0.359 | 61.178 | G-alpha (PF00503, IPR001019, SM00275): G-protein alpha subunit |
54 |
GNAI2 | oncoprotein | 18 | 0.235 | 131.304 | G-alpha (PF00503, IPR001019, SM00275): G-protein alpha subunit |
55 |
GNAI3 | interactor | 17 | 0.287 | 225.048 | G-alpha (PF00503, IPR001019, SM00275): G-protein alpha subunit |
56 |
GNAQ | oncoprotein | 7 | 0.333 | 25.234 | G-alpha (PF00503, IPR001019, SM00275): G-protein alpha subunit |
57 |
GNAS | oncoprotein | 16 | 0.200 | 198.246 | G-alpha (PF00503, IPR001019, SM00275): G-protein alpha subunit |
58 |
GNG10 | interactor | 5 | 0.700 | 1.404 | G-gamma (PF00631, IPR015898, SM00224): GGL domain |
59 |
GNG11 | interactor | 2 | 1.000 | 0 | G-gamma (PF00631, IPR015898, SM00224): GGL domain |
60 |
GNG12 | interactor | 4 | 0.500 | 1.862 | G-gamma (PF00631, IPR015898, SM00224): GGL domain |
61 |
GNG13 | interactor | 1 | 0 | 0 | G-gamma (PF00631, IPR015898, SM00224): GGL domain |
62 |
GNG2 | interactor | 18 | 0.183 | 173.129 | G-gamma (PF00631, IPR015898, SM00224): GGL domain SidE (PF12252, IPR021014): Dot/Icm substrate protein |
63 |
GNG3 | interactor | 1 | 0 | 0 | G-gamma (PF00631, IPR015898, SM00224): GGL domain |
64 |
GNG4 | interactor | 5 | 0.700 | 1.404 | G-gamma (PF00631, IPR015898, SM00224): GGL domain |
65 |
GNG5 | interactor | 6 | 0.533 | 8.949 | G-gamma (PF00631, IPR015898, SM00224): GGL domain |
66 |
GNG7 | interactor | 4 | 1.000 | 0 | G-gamma (PF00631, IPR015898, SM00224): GGL domain |
67 |
GNG8 | interactor | 1 | 0 | 0 | G-gamma (PF00631, IPR015898, SM00224): GGL domain |
68 |
GNGT1 | interactor | 2 | 1.000 | 0 | G-gamma (PF00631, IPR015898, SM00224): GGL domain |
69 |
GNGT2 | interactor | 1 | 0 | 0 | G-gamma (PF00631, IPR015898, SM00224): GGL domain |
70 |
GNS | interactor | 8 | 0.750 | 71.195 | Sulfatase (PF00884, IPR000917): Sulfatase DUF4976 (PF16347, IPR032506): Domain of unknown function (DUF4976) |
71 |
GRK2 | interactor | 5 | 0.400 | 7.048 | ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) PH (PF00169, IPR001849, SM00233): PH domain Pkinase (PF00069, IPR000719): Protein kinase domain RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain |
72 |
GZMB | interactor | 5 | 0.700 | 2.274 | Trypsin (PF00089, IPR001254, SM00020): Trypsin |
73 |
HDAC4 | oncoprotein | 7 | 0.333 | 41.388 | Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4 |
74 |
HDAC5 | protein found in more fusions | 10 | 0.389 | 45.451 | Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain NOA36 (PF06524, IPR010531): NOA36 protein Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3 HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4 |
75 |
HSPA5 | oncoprotein | 15 | 0.176 | 198.627 | HSP70 (PF00012, IPR013126): Hsp70 protein |
76 |
KALRN | oncoprotein | 2 | 1.000 | 0 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain PH (PF00169, IPR001849, SM00233): PH domain Pkinase (PF00069, IPR000719): Protein kinase domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain SH3_2 (PF07653, IPR011511): Variant SH3 domain Spectrin (PF00435, IPR002017): Spectrin repeat UPF0302 (PF08864, IPR014963): UPF0302 domain CRAL_TRIO (PF00650, IPR001251, SM00516): CRAL/TRIO domain HAD_2 (PF13419, IPR023214): Haloacid dehalogenase-like hydrolase SH3_9 (PF14604, IPR001452): Variant SH3 domain PH_10 (PF15411): Pleckstrin homology domain SH3-RhoG_link (PF16609): SH3-RhoGEF linking unstructured region |
77 |
KCNJ3 | interactor | 2 | 1.000 | 0 | IRK (PF01007, IPR016449): Inward rectifier potassium channel |
78 |
MCF2 | oncoprotein | 2 | 0 | 0 | PH (PF00169, IPR001849, SM00233): PH domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain Spectrin (PF00435, IPR002017): Spectrin repeat CRAL_TRIO_2 (PF13716, IPR001251): Divergent CRAL/TRIO domain SPG48 (PF14764, IPR028222): AP-5 complex subunit, vesicle trafficking |
79 |
MCF2L | interactor | 1 | 0 | 0 | PH (PF00169, IPR001849, SM00233): PH domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain Spectrin (PF00435, IPR002017): Spectrin repeat CRAL_TRIO_2 (PF13716, IPR001251): Divergent CRAL/TRIO domain SH3_9 (PF14604, IPR001452): Variant SH3 domain DUF4771 (PF15995, IPR031936): Domain of unknown function (DUF4771) |
80 |
MRGPRX1 | interactor | 4 | 0.500 | 1.567 | 7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family) RAMP4 (PF06624, IPR010580): Ribosome associated membrane protein RAMP4 |
81 |
MTNR1A | interactor | 7 | 0.381 | 22.051 | 7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family) TctB (PF07331, IPR009936): Tripartite tricarboxylate transporter TctB family |
82 |
MTOR | oncoprotein | 12 | 0.345 | 90.587 | DUF1104 (PF06518, IPR009488): Protein of unknown function (DUF1104) EPSP_synthase (PF00275, IPR001986): EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain HEAT (PF02985, IPR000357): HEAT repeat FRB_dom (PF08771, IPR009076): FKBP12-rapamycin binding domain V-ATPase_H_N (PF03224, IPR004908): V-ATPase subunit H PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats TPR_19 (PF14559): Tetratricopeptide repeat |
83 |
MVD | interactor | 10 | 0.806 | 3.862 | GHMP_kinases_N (PF00288, IPR006204): GHMP kinases N terminal domain |
84 |
NCF2 | interactor | 4 | 1.000 | 0 | PB1 (PF00564, IPR000270, SM00666): PB1 domain TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat SH3_1 (PF00018, IPR001452, SM00326): SH3 domain TPR_16 (PF13432): Tetratricopeptide repeat |
85 |
NOL11 | interactor | 2 | 0 | 36.190 | NUC205 (PF08168, IPR012584): NUC205 domain DUF2779 (PF11074, IPR021301): Domain of unknown function(DUF2779) |
86 |
NR3C1 | protein found in more fusions | 8 | 0.286 | 78.534 | GCR (PF02155, IPR001409): Glucocorticoid receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
87 |
NTRK1 | oncoprotein | 31 | 0.133 | 1119.720 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain |
88 |
PAK1 | oncoprotein | 4 | 1.000 | 0 | PBD (PF00786, IPR000095, SM00285): P21-Rho-binding domain Pkinase (PF00069, IPR000719): Protein kinase domain |
89 |
PAN2 | interactor | 12 | 0.212 | 107.945 | RNase_T (PF00929, IPR013520): Exonuclease UCH_1 (PF13423, IPR001394): Ubiquitin carboxyl-terminal hydrolase WD40_like (PF17005, IPR031544): WD40-like domain |
90 |
PARP1 | suppressor | 14 | 0.179 | 157.950 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain PADR1 (PF08063, IPR012982): PADR1 (NUC008) domain PARP (PF00644, IPR012317): Poly(ADP-ribose) polymerase catalytic domain PARP_reg (PF02877, IPR004102): Poly(ADP-ribose) polymerase, regulatory domain WGR (PF05406, IPR008893, SM00773): WGR domain zf-PARP (PF00645, IPR001510): Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region |
91 |
PDCL | interactor | 7 | 0.381 | 42.136 | Phosducin (PF02114, IPR024253): Phosducin |
92 |
PDLIM7 | interactor | 8 | 0.321 | 52.870 | LIM (PF00412, IPR001781, SM00132): LIM domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) zinc_ribbon_10 (PF10058, IPR019273): Predicted integral membrane zinc-ribbon metal-binding protein DUF4749 (PF15936, IPR031847): Domain of unknown function (DUF4749) |
93 |
PEPD | interactor | 10 | 0.667 | 22.782 | AMP_N (PF05195, IPR007865, SM01011): Aminopeptidase P, N-terminal domain Peptidase_M24 (PF00557, IPR001714): Metallopeptidase family M24 DUF3793 (PF12672, IPR024523): Protein of unknown function (DUF3793) |
94 |
PIK3CG | oncoprotein | 3 | 1.000 | 0 | Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain PI3K_C2 (PF00792, IPR002420, SM00142): Phosphoinositide 3-kinase C2 PI3K_rbd (PF00794, IPR000341, SM00144): PI3-kinase family, ras-binding domain PI3Ka (PF00613, IPR001263, SM00145): Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase DUF3244 (PF11589, IPR021638): Domain of unknown function (DUF3244) DUF4135 (PF13575, IPR025410): Domain of unknown function (DUF4135) |
95 |
PIK3R5 | oncoprotein | 3 | 1.000 | 0 | PI3K_1B_p101 (PF10486, IPR019522): Phosphoinositide 3-kinase gamma adapter protein p101 subunit |
96 |
PLA2G4B | interactor | 3 | 1.000 | 0 | C2 (PF00168, IPR000008, SM00239): C2 domain PLA2_B (PF01735, IPR002642): Lysophospholipase catalytic domain |
97 |
PLEKHG2 | oncoprotein | 2 | 1.000 | 0 | PH (PF00169, IPR001849, SM00233): PH domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
98 |
PTGES3 | interactor | 8 | 0.238 | 100.759 | CS (PF04969, IPR007052): CS domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
99 |
PTK2 | protein found in more fusions | 8 | 0.429 | 34.499 | FERM_M (PF00373, IPR019748): FERM central domain Focal_AT (PF03623, IPR005189): Focal adhesion targeting region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase UCMA (PF17085, IPR031386): Unique cartilage matrix associated protein |
100 |
RACK1 | suppressor | 15 | 0.209 | 338.096 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
101 |
RADIL | interactor | 2 | 1.000 | 0 | DIL (PF01843, IPR018444, SM01132): DIL domain FHA (PF00498, IPR000253, SM00240): FHA domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain |
102 |
RAP1A | suppressor | 8 | 0.286 | 87.573 | Ras (PF00071, IPR001806, SM00173): Ras family |
103 |
RASD1 | interactor | 2 | 1.000 | 0 | Arf (PF00025, IPR006689, SM00177): ADP-ribosylation factor family Ras (PF00071, IPR001806, SM00173): Ras family |
104 |
RASD2 | interactor | 1 | 0 | 0 | Ras (PF00071, IPR001806, SM00173): Ras family |
105 |
RB1 | suppressor | 8 | 0.464 | 77.260 | RB_A (PF01858, IPR002720): Retinoblastoma-associated protein A domain RB_B (PF01857, IPR002719): Retinoblastoma-associated protein B domain Rb_C (PF08934, IPR015030): Rb C-terminal domain DUF3452 (PF11934, IPR024599): Domain of unknown function (DUF3452) DUF4592 (PF15262, IPR028030): Domain of unknown function (DUF4592) |
106 |
RGS6 | interactor | 1 | 0 | 0 | DEP (PF00610, IPR000591, SM00049): Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain G-gamma (PF00631, IPR015898, SM00224): GGL domain |
107 |
RICTOR | interactor | 7 | 0.667 | 6.626 | RasGEF_N_2 (PF14663, IPR029453): Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_N (PF14664, IPR028267): Rapamycin-insensitive companion of mTOR, N-term RICTOR_phospho (PF14665, IPR029259): Rapamycin-insensitive companion of mTOR, phosphorylation-site RICTOR_M (PF14666, IPR029451): Rapamycin-insensitive companion of mTOR, middle domain RICTOR_V (PF14668, IPR029452): Rapamycin-insensitive companion of mTOR, domain 5 |
108 |
ROCK1 | interactor | 4 | 0.167 | 21.251 | FPP (PF05911, IPR008587): Filament-like plant protein, long coiled-coil ZapB (PF06005, IPR009252): Cell division protein ZapB HR1 (PF02185, IPR011072, SM00742): Hr1 repeat PH (PF00169, IPR001849, SM00233): PH domain Phage_GP20 (PF06810, IPR009636): Phage minor structural protein GP20 Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain Rho_Binding (PF08912, IPR015008): Rho Binding SlyX (PF04102, IPR007236): SlyX Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding Lzipper-MIP1 (PF14389, IPR025757): Leucine-zipper of ternary complex factor MIP1 PKcGMP_CC (PF16808, IPR031831): Coiled-coil N-terminus of cGMP-dependent protein kinase |
109 |
RPS6KA1 | oncoprotein | 14 | 0.440 | 306.220 | Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
110 |
RPTOR | protein found in more fusions | 10 | 0.444 | 100.968 | HEAT (PF02985, IPR000357): HEAT repeat WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain HEAT_2 (PF13646): HEAT repeats Raptor_N (PF14538, IPR029347): Raptor N-terminal CASPase like domain |
111 |
SAT1 | protein found in more fusions | 5 | 0.333 | 30.120 | Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family |
112 |
SP1 | protein found in more fusions | 9 | 0.321 | 72.012 | zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Miga (PF10265, IPR019392): Mitoguardin zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
113 |
SPAG1 | interactor | 1 | 0 | 0 | TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat DUF3597 (PF12200, IPR022016): Domain of unknown function (DUF3597) TPR_7 (PF13176, IPR019734): Tetratricopeptide repeat TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat RPAP3_C (PF13877, IPR025986): Potential Monad-binding region of RPAP3 TPR_19 (PF14559): Tetratricopeptide repeat |
114 |
SPTAN1 | oncoprotein | 16 | 0.242 | 270.883 | EFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand Spectrin (PF00435, IPR002017): Spectrin repeat SH3_1 (PF00018, IPR001452, SM00326): SH3 domain Tetrabrachion (PF11401, IPR021535): Tetrabrachion EF-hand_7 (PF13499, IPR011992): EF-hand domain pair E2F_CC-MB (PF16421, IPR032198): E2F transcription factor CC-MB domain |
115 |
STAT1 | suppressor | 13 | 0.227 | 104.944 | SH2 (PF00017, IPR000980, SM00252): SH2 domain STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain STAT1_TAZ2bind (PF12162, IPR022752): STAT1 TAZ2 binding domain |
116 |
SVIL | interactor | 10 | 0.333 | 47.818 | Gelsolin (PF00626, IPR007123): Gelsolin repeat VHP (PF02209, IPR003128, SM00153): Villin headpiece domain DUF4695 (PF15766, IPR031521): Domain of unknown function (DUF4695) |
117 |
SYNPO | interactor | 7 | 0.476 | 16.015 | Calsarcin (PF05556, IPR008438): Calcineurin-binding protein (Calsarcin) |
118 |
TBXA2R | interactor | 8 | 0.476 | 10.107 | 7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family) |
119 |
TERF1 | interactor | 9 | 0.143 | 150.806 | TRF (PF08558, IPR013867): Telomere repeat binding factor (TRF) Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain |
120 |
TNFRSF1A | oncoprotein | 12 | 0.345 | 159.242 | Death (PF00531, IPR000488, SM00005): Death domain TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region |
121 |
UBQLN1 | protein found in more fusions | 6 | 0.400 | 54.985 | Clathrin-link (PF09268, IPR015348): Clathrin, heavy-chain linker UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain XPC-binding (PF09280, IPR015360): XPC-binding domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family Fur_reg_FbpB (PF13040, IPR025004): Fur-regulated basic protein B FAM199X (PF15814, IPR029672): Protein family FAM199X |
122 |
VCAM1 | interactor | 11 | 0.327 | 141.531 | C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain |
123 |
VCP | protein found in more fusions | 26 | 0.170 | 624.965 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2 CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain TniB (PF05621, IPR008868): Bacterial TniB protein Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944) |
124 |
VIM | suppressor | 16 | 0.248 | 205.157 | Filament (PF00038, IPR001664): Intermediate filament protein Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region |
125 |
WDR26 | interactor | 4 | 0.500 | 2.952 | eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 |
126 |
XIAP | interactor | 18 | 0.397 | 336.708 | BIR (PF00653, IPR001370, SM00238): Inhibitor of Apoptosis domain zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
127 |
XPO1 | interactor | 22 | 0.199 | 483.769 | CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain Xpo1 (PF08389, IPR013598): Exportin 1-like protein Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region |