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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)341
The number (and %) of the onco-proteins94 (27.57 %)
The number (and %) of the tumor suppressors36 (10.56 %)
Total number of binary PPIs (saturation %)3820 (6.59 %)
The number (and %) of affected PPIs348 (9.11 %)
The number of possible different fusions49
PPI diameter4
PPI radius2
The average degree of PPI21.883
Assortativity coefficient-0.2716
The network average Clustering coefficient0.523
The number (and %) of a zero Clustering coefficients18 (5.28 %)
The number (and %) of a zero Betweenness Centrality48 (14.08 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: CUL4A,GNAS All fusions
Proteins found in more fusions GRK5 (see 2 fusions); RUVBL1 (see 1 fusions); NTRK1/TFG (see 1 fusions); NPM1 (see 1 fusions); DCAF1 (see 1 fusions); COMMD1 (see 1 fusions); CUL1 (see 3 fusions); LGALS3BP (see 2 fusions); PCBD1 (see 1 fusions); RPS18/TUBG1 (see 1 fusions); OPTN (see 1 fusions); EWSR1 (see 1 fusions); PRDX1 (see 1 fusions); SAMHD1 (see 1 fusions); PCNA (see 1 fusions); DDX5 (see 1 fusions); RPLP2 (see 1 fusions); ARIH1 (see 4 fusions); CUL4A (see 4 fusions); VCP (see 4 fusions); HSP90AA1 (see 6 fusions); PRMT5 (see 1 fusions); GNAS (see 5 fusions); TLE2 (see 2 fusions); HSP90AB1 (see 3 fusions); COPS5/HNRNPH3 (see 3 fusions); HNRNPD (see 1 fusions); NF2 (see 1 fusions); TUBA1B/TUBA1C (see 11 fusions); HSP90AA1/BAG4 (see 1 fusions); DDB1 (see 4 fusions); NCL (see 4 fusions); HSPA8/HSPD1 (see 1 fusions); TUBG1 (see 1 fusions); EEF1A1 (see 6 fusions); NTRK1/RPL7A (see 1 fusions); CUL3 (see 1 fusions); MYC (see 2 fusions); UBE2E3 (see 5 fusions); COPS5 (see 1 fusions); UBC (see 7 fusions); HSP90AA1/TUBB (see 1 fusions); TP53 (see 3 fusions); PABPC1 (see 3 fusions); NFKB1 (see 2 fusions); EGFR (see 2 fusions); MCM2 (see 1 fusions); RPTOR (see 3 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 CUL4Aparental protein2790.07239445.973Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
2 GNASparental protein690.0598939.206G-alpha (PF00503, IPR001019, SM00275): G-protein alpha subunit
3 ABCA10interactor21.0000ABC_tran (PF00005, IPR003439): ABC transporter
DUF258 (PF03193, IPR004881): Protein of unknown function, DUF258
Wzy_C (PF04932, IPR007016): O-Antigen ligase
ABC2_membrane_3 (PF12698): ABC-2 family transporter protein
AAA_21 (PF13304, IPR003959): AAA domain, putative AbiEii toxin, Type IV TA system
SbcCD_C (PF13558): Putative exonuclease SbcCD, C subunit
DUF4162 (PF13732, IPR025302): Domain of unknown function (DUF4162)
Cadherin_C_2 (PF16492, IPR032455): Cadherin cytoplasmic C-terminal
4 ABCE1interactor210.289515.143ABC_tran (PF00005, IPR003439): ABC transporter
Fer4 (PF00037, IPR001450): 4Fe-4S binding domain
RLI (PF04068, IPR007209): Possible Fer4-like domain in RNase L inhibitor, RLI
SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
Fer4_7 (PF12838, IPR001450): 4Fe-4S dicluster domain
AAA_29 (PF13555): P-loop containing region of AAA domain
5 ADCY2interactor100DUF1053 (PF06327, IPR009398): Domain of Unknown Function (DUF1053)
HNOBA (PF07701, IPR011645): Heme NO binding associated
Guanylate_cyc (PF00211, IPR001054, SM00044): Adenylate and Guanylate cyclase catalytic domain
DUF3487 (PF11990, IPR021877): Protein of unknown function (DUF3487)
DUF4131 (PF13567, IPR025405): Domain of unknown function (DUF4131)
AC_N (PF16214, IPR032628): Adenylyl cyclase N-terminal extracellular and transmembrane region
6 ADCY6interactor100DUF1053 (PF06327, IPR009398): Domain of Unknown Function (DUF1053)
HNOBA (PF07701, IPR011645): Heme NO binding associated
PRA1 (PF03208, IPR004895): PRA1 family protein
DUF2207 (PF09972, IPR018702): Predicted membrane protein (DUF2207)
Guanylate_cyc (PF00211, IPR001054, SM00044): Adenylate and Guanylate cyclase catalytic domain
Shisa (PF13908, IPR026910): Wnt and FGF inhibitory regulator
AC_N (PF16214, IPR032628): Adenylyl cyclase N-terminal extracellular and transmembrane region
7 ADRB2interactor320.140468.6107tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
8 AK9oncoprotein21.0000ADK (PF00406, IPR000850): Adenylate kinase
Cwf_Cwc_15 (PF04889, IPR006973): Cwf15/Cwc15 cell cycle control protein
GN3L_Grn1 (PF08701, IPR014813): GNL3L/Grn1 putative GTPase
Josephin (PF02099, IPR006155): Josephin
MAS20 (PF02064, IPR002056): MAS20 protein import receptor
YHS (PF04945, IPR007029): YHS domain
RNA_pol_3_Rpc31 (PF11705, IPR024661): DNA-directed RNA polymerase III subunit Rpc31
DUF3508 (PF12018, IPR021897): Domain of unknown function (DUF3508)
AAA_14 (PF13173): AAA domain
AAA_16 (PF13191): AAA ATPase domain
AAA_17 (PF13207): AAA domain
AAA_18 (PF13238): AAA domain
9 AMBRA1interactor170.44129.993Acyl_CoA_thio (PF02551, IPR025652): Acyl-CoA thioesterase
eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Spt20 (PF12090, IPR021950): Spt20 family
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
10 ANAPC5interactor40.6672.470TPR_4 (PF07721, IPR011717): Tetratricopeptide repeat
ANAPC5 (PF12862, IPR026000): Anaphase-promoting complex subunit 5
TPR_6 (PF13174, IPR019734): Tetratricopeptide repeat
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_16 (PF13432): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
11 ARIH1protein found in more fusions70.8670.257CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain
IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain
Med14 (PF08638, IPR013947): Mediator complex subunit MED14
zinc_ribbon_2 (PF13240, IPR026870): zinc-ribbon domain
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain
12 ARMCX3oncoprotein203.872Arm_2 (PF04826, IPR006911): Armadillo-like
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
13 ASB4interactor70.5242.294Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
SOCS_box (PF07525, IPR001496): SOCS box
14 AVPR2interactor50.30019.8227tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
15 AXIN1suppressor90.35737.303Axin_b-cat_bind (PF08833, IPR014936): Axin beta-catenin binding domain
RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain
DIX (PF00778, IPR001158, SM00021): DIX domain
AXIN1_TNKS_BD (PF16646, IPR032101): Axin-1 tankyrase binding domain
16 BAG4protein found in more fusions140.7918.852BAG (PF02179, IPR003103, SM00264): BAG domain
DMP12 (PF16779, IPR031891): DNA-mimic protein
17 BANF1interactor120.32723.413BAF (PF02961, IPR004122, SM01023): Barrier to autointegration factor
18 BRWD1interactor60.6673.775WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
SEEEED (PF14797, IPR029394): Serine-rich region of AP3B1, clathrin-adaptor complex
19 BTRConcoprotein350.291288.734WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
F-box-like (PF12937, IPR001810): F-box-like
20 C1QBPinteractor300.423498.829MAM33 (PF02330, IPR003428): Mitochondrial glycoprotein
DUF3053 (PF11254, IPR021413): Protein of unknown function (DUF3053)
21 CA2interactor60.8670.500Carb_anhydrase (PF00194, IPR001148, SM01057): Eukaryotic-type carbonic anhydrase
22 CALM1interactor290.246514.311EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
23 CAND1interactor1230.1902015.636Adaptin_N (PF01602, IPR002553): Adaptin N terminal region
DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981)
HEAT (PF02985, IPR000357): HEAT repeat
TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20)
RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1
DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385)
MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II
24 CARNMT1interactor21.0000N2227 (PF07942, IPR012901): N2227-like protein
RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
25 CASToncoprotein31.0000Band_3_cyto (PF07565, IPR013769): Band 3 cytoplasmic domain
Calpain_inhib (PF00748, IPR001259): Calpain inhibitor
Maf_N (PF08383, IPR013592): Maf N-terminal region
26 CATsuppressor70.60017.738Catalase (PF00199, IPR011614, SM01060): Catalase
Catalase-rel (PF06628, IPR010582): Catalase-related immune-responsive
27 CCDC8interactor550.205855.209Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
PNMA (PF14893, IPR026523): PNMA
28 CCNG1oncoprotein41.0000Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
29 CCT5interactor260.289150.703Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
30 CDC5Linteractor550.233976.012OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat
Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component
Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain
31 CDKN1Asuppressor310.344258.610CDI (PF02234, IPR003175): Cyclin-dependent kinase inhibitor
32 CDKN1Bsuppressor160.58322.464CDI (PF02234, IPR003175): Cyclin-dependent kinase inhibitor
Multi-haem_cyto (PF13447): Seven times multi-haem cytochrome CxxCH
33 CDT1oncoprotein150.43833.849CDT1 (PF08839, IPR014939, SM01075): DNA replication factor CDT1 like
CDT1_C (PF16679, IPR032054): DNA replication factor Cdt1 C-terminal domain
34 CDY2Ainteractor100Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
ECH_1 (PF00378, IPR001753): Enoyl-CoA hydratase/isomerase
Mrr_cat (PF04471, IPR007560): Restriction endonuclease
DUF2607 (PF10795, IPR019731): Protein of unknown function (DUF2607)
35 CDY2Binteractor100Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
ECH_1 (PF00378, IPR001753): Enoyl-CoA hydratase/isomerase
Mrr_cat (PF04471, IPR007560): Restriction endonuclease
DUF2607 (PF10795, IPR019731): Protein of unknown function (DUF2607)
36 CENPAinteractor130.31819.311Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
37 CHEK1suppressor150.52416.474Pkinase (PF00069, IPR000719): Protein kinase domain
38 CHEK2suppressor100.472117.234FHA (PF00498, IPR000253, SM00240): FHA domain
Pkinase (PF00069, IPR000719): Protein kinase domain
39 CLCN1interactor41.0000CBS (PF00571, IPR000644, SM00116): CBS domain
Voltage_CLC (PF00654, IPR001807): Voltage gated chloride channel
40 COMMD1protein found in more fusions90.6793.412COMMD1_N (PF17221): COMMD1 N-terminal domain
COMM_domain (PF07258): COMM domain
41 COPS2suppressor320.502123.673YozE_SAM_like (PF06855, IPR023089): YozE SAM-like fold
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
DUF2087 (PF09860, IPR018656): Uncharacterized protein conserved in bacteria (DUF2087)
PCI (PF01399, IPR000717, SM00088): PCI domain
TPR_7 (PF13176, IPR019734): Tetratricopeptide repeat
42 COPS3interactor380.496126.513RasGEF (PF00617, IPR001895, SM00147): RasGEF domain
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
PCI (PF01399, IPR000717, SM00088): PCI domain
43 COPS4interactor370.511133.439DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
PCI (PF01399, IPR000717, SM00088): PCI domain
TPR_7 (PF13176, IPR019734): Tetratricopeptide repeat
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_14 (PF13428): Tetratricopeptide repeat
44 COPS5protein found in more fusions1580.1534567.346JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
45 COPS6interactor1090.1951927.898DUF320 (PF03777, IPR005528): Small secreted domain (DUF320)
JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function
46 COPS7Ainteractor320.55485.043PCI (PF01399, IPR000717, SM00088): PCI domain
47 COPS7Binteractor210.8674.643PCI (PF01399, IPR000717, SM00088): PCI domain
48 COPS8interactor260.70323.494CSN8_PSD8_EIF3K (PF10075): CSN8/PSMD8/EIF3K family
49 COPS9interactor150.8294.312MYEOV2 (PF15004, IPR029391): Myeloma-overexpressed-like
50 CPT2interactor100Carn_acyltransf (PF00755, IPR000542): Choline/Carnitine o-acyltransferase
51 CRBNinteractor120.57611.099LON_substr_bdg (PF02190, IPR003111, SM00464): ATP-dependent protease La (LON) substrate-binding domain
Yippee-Mis18 (PF03226, IPR004910): Yippee zinc-binding/DNA-binding /Mis18, centromere assembly
52 CRHR1interactor21.00007tm_2 (PF00002, IPR000832): 7 transmembrane receptor (Secretin family)
HRM (PF02793, IPR001879, SM00008): Hormone receptor domain
53 CSN1S1interactor41.0000zf-Tim10_DDP (PF02953, IPR004217): Tim10/DDP family zinc finger
Gly-rich_Ago1 (PF12764, IPR024357): Glycine-rich region of argonaut
54 CTNNB1oncoprotein350.269325.644Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361)
HEAT_EZ (PF13513): HEAT-like repeat
55 CUL1suppressor1580.1464473.293Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
56 CUL3protein found in more fusions1620.1425569.699Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
57 CUL4Boncoprotein1560.1315680.776Cullin (PF00888, IPR001373, SM00182): Cullin family
EBP50_C (PF09007, IPR015098): EBP50, C-terminal
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
PG_binding_4 (PF12229, IPR022029): Putative peptidoglycan binding domain
MDFI (PF15316, IPR026134): MyoD family inhibitor
58 CUL5suppressor1370.1683137.526Cullin (PF00888, IPR001373, SM00182): Cullin family
GlutR_dimer (PF00745, IPR015896): Glutamyl-tRNAGlu reductase, dimerisation domain
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
59 DAB2IPsuppressor70.5245.538C2 (PF00168, IPR000008, SM00239): C2 domain
PH_2 (PF08458, IPR013666): Plant pleckstrin homology-like region
RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase
DUF3498 (PF12004, IPR021887): Domain of unknown function (DUF3498)
60 DBN1oncoprotein150.305131.098Pinin_SDK_memA (PF04696, IPR006786): pinin/SDK/memA/ protein conserved region
Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein
CAF-1_p150 (PF11600): Chromatin assembly factor 1 complex p150 subunit, N-terminal
MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
61 DCAF1protein found in more fusions330.435126.153DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913)
LisH (PF08513, IPR013720, SM00667): LisH
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated
62 DCAF10interactor61.0000WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
63 DCAF11interactor150.8483.077WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
64 DCAF12interactor51.0000ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
WD40_like (PF17005, IPR031544): WD40-like domain
65 DCAF12L2interactor21.0000WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
66 DCAF15interactor31.0000DCAF15_WD40 (PF14939, IPR032734): DDB1-and CUL4-substrate receptor 15, WD repeat
67 DCAF16interactor61.0000DCA16 (PF15349, IPR028216): DDB1- and CUL4-associated factor 16
68 DCAF17interactor51.0000DCAF17 (PF15802, IPR031620): DDB1- and CUL4-associated factor 17
69 DCAF4interactor90.8891.315WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
DUF4221 (PF13970, IPR025316): Domain of unknown function (DUF4221)
70 DCAF4L1interactor31.0000WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
zf-CHC2 (PF01807, IPR002694): CHC2 zinc finger
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
71 DCAF4L2interactor31.0000WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
72 DCAF5interactor70.5246.987WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
DUF2634 (PF10934, IPR020288): Protein of unknown function (DUF2634)
IMUP (PF15761, IPR026621): Immortalisation up-regulated protein
73 DCAF6interactor61.0000Herpes_pp85 (PF04637, IPR006731): Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25)
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
DUF3408 (PF11888, IPR021823): Protein of unknown function (DUF3408)
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
ATAD4 (PF15321, IPR028237): ATPase family AAA domain containing 4
MRI (PF15325, IPR028278): Modulator of retrovirus infection
WD40_like (PF17005, IPR031544): WD40-like domain
74 DCAF7interactor80.5365.279WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
75 DCAF8interactor150.62932.188DUF1635 (PF07795, IPR012862): Protein of unknown function (DUF1635)
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
DUF4661 (PF15576, IPR029073): Domain of unknown function (DUF4661)
76 DCST1interactor100DC_STAMP (PF07782, IPR012858): DC-STAMP-like protein
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
77 DCUN1D1interactor900.247851.085Cullin_binding (PF03556, IPR005176): Cullin binding
UBA_4 (PF14555): UBA-like domain
78 DCUN1D2interactor90.8890.718Cullin_binding (PF03556, IPR005176): Cullin binding
UBA_4 (PF14555): UBA-like domain
79 DCUN1D3suppressor80.8930.384Cullin_binding (PF03556, IPR005176): Cullin binding
80 DCUN1D4interactor80.8930.384Cullin_binding (PF03556, IPR005176): Cullin binding
81 DCUN1D5interactor90.8890.693Cullin_binding (PF03556, IPR005176): Cullin binding
82 DDA1interactor380.309275.410DDA1 (PF10172, IPR018276): Det1 complexing ubiquitin ligase
83 DDB1protein found in more fusions1050.1383729.473CPSF_A (PF03178, IPR004871): CPSF A subunit region
MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term
84 DDB2suppressor250.55149.441WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
85 DDIT4interactor31.0000RTP801_C (PF07809, IPR012918): RTP801 C-terminal region
86 DDX21interactor120.36423.146CRT10 (PF08728, IPR014839): CRT10
DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
GUCT (PF08152, IPR012562): GUCT (NUC152) domain
Sulfatase (PF00884, IPR000917): Sulfatase
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal
87 DDX5oncoprotein340.48771.434DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
P68HR (PF08061, IPR012587): P68HR (NUC004) repeat
ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
88 DET1interactor90.7502.669Det1 (PF09737, IPR019138): De-etiolated protein 1 Det1
89 DHX15interactor270.50155.097DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold
DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2)
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
AAA_29 (PF13555): P-loop containing region of AAA domain
90 DHX9oncoprotein320.478158.183DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold
T2SSE (PF00437, IPR001482): Type II/IV secretion system protein
HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2)
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
91 DICER1suppressor100.6113.859DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
Dicer_dimer (PF03368, IPR005034): Dicer dimerisation domain
PAZ (PF02170, IPR003100, SM00949): PAZ domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
Ribonuclease_3 (PF00636, IPR000999, SM00535): Ribonuclease III domain
PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
DUF4611 (PF15387, IPR027893): Domain of unknown function (DUF4611)
92 DIS3interactor50.60029.137RNB (PF00773, SM00955): RNB domain
rve (PF00665, IPR001584): Integrase core domain
PIN_4 (PF13638, IPR002716): PIN domain
Rrp44_CSD1 (PF17216): Rrp44-like cold shock domain
Rrp44_S1 (PF17215): S1 domain
93 DLC1suppressor51.0000RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
START (PF01852, IPR002913, SM00234): START domain
DUF4561 (PF15120, IPR027818): Domain of unknown function (DUF4561)
94 DNAJC10interactor150.73310.313DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
Thioredoxin (PF00085, IPR013766): Thioredoxin
Thioredoxin_6 (PF13848): Thioredoxin-like domain
95 DNAJC7interactor170.478186.329DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
Rapsyn_N (PF10579, IPR019568): Rapsyn N-terminal myristoylation and linker region
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_17 (PF13431): Tetratricopeptide repeat
96 DNMT3Bsuppressor90.5564.973DNA_methylase (PF00145, IPR001525): C-5 cytosine-specific DNA methylase
PWWP (PF00855, IPR000313, SM00293): PWWP domain
97 DPPA4interactor100.4449.854Ribosomal_L40e (PF01020, IPR001975): Ribosomal L40e family
DCR (PF14047, IPR025891): Dppa2/4 conserved region
Dppa2_A (PF14049, IPR025892): Dppa2/4 conserved region in higher vertebrates
98 DTLinteractor210.45755.176WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
99 EEDsuppressor550.194470.559WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
100 EEF1A1suppressor560.352905.958GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain
101 EEF1A2oncoprotein160.7252.924GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain
102 EGFRoncoprotein430.221760.593Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT)
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
103 EIF4Hinteractor90.36175.749eIF-4B (PF06273, IPR010433): Plant specific eukaryotic initiation factor 4B
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
104 ELMSAN1interactor21.0000ELM2 (PF01448, IPR000949): ELM2 domain
FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid)
Ndc1_Nup (PF09531, IPR019049): Nucleoporin protein Ndc1-Nup
zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
105 EMDinteractor230.355106.341LEM (PF03020, IPR003887, SM00540): LEM domain
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
106 EML2interactor204.443CPSF_A (PF03178, IPR004871): CPSF A subunit region
HELP (PF03451, IPR005108): HELP motif
SlyX (PF04102, IPR007236): SlyX
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
KAAG1 (PF15354, IPR029407): Kidney-associated antigen 1
107 ENO1oncoprotein220.51997.163Enolase_C (PF00113, IPR020810): Enolase, C-terminal TIM barrel domain
Enolase_N (PF03952, IPR020811): Enolase, N-terminal domain
108 ERCC6oncoprotein170.51518.329Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
Spt5-NGN (PF03439, IPR005100): Early transcription elongation factor of RNA pol II, NGN section
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
109 ERCC8oncoprotein260.51754.153WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
DUF4859 (PF16151, IPR032339): Domain of unknown function (DUF4859)
110 EWSR1oncoprotein520.313662.707RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
Keratin_2_head (PF16208, IPR032444): Keratin type II head
111 FBXW5interactor90.55619.635WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
F-box-like (PF12937, IPR001810): F-box-like
112 FBXW8interactor120.65213.175WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
F-box-like (PF12937, IPR001810): F-box-like
113 FLNAsuppressor200.358227.007CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
Filamin (PF00630, IPR017868): Filamin/ABP280 repeat
114 FSCN1oncoprotein60.66712.748Fascin (PF06268, IPR022768): Fascin domain
115 FUSsuppressor540.384863.712Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
Limkain-b1 (PF11608, IPR024582): Limkain b1
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
Keratin_2_head (PF16208, IPR032444): Keratin type II head
116 GIPC1interactor30.6674.422PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
117 GLMNoncoprotein60.8670.417Kinetochor_Ybp2 (PF08568, IPR013877): Uncharacterised protein family, YAP/Alf4/glomulin
118 GNA11oncoprotein60.4676.313G-alpha (PF00503, IPR001019, SM00275): G-protein alpha subunit
119 GNA12oncoprotein50.20028.461G-alpha (PF00503, IPR001019, SM00275): G-protein alpha subunit
120 GNALinteractor100BEX (PF04538, IPR021156): Brain expressed X-linked like family
G-alpha (PF00503, IPR001019, SM00275): G-protein alpha subunit
121 GNAQoncoprotein140.165265.423G-alpha (PF00503, IPR001019, SM00275): G-protein alpha subunit
122 GNB1interactor190.211974.245Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
123 GNB2interactor190.216996.147WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
CALM_bind (PF16025): Calcium-dependent calmodulin binding
WD40_like (PF17005, IPR031544): WD40-like domain
124 GNB3interactor80372.463Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
125 GNB4interactor120.227538.317Spore_YhcN_YlaJ (PF09580, IPR019076): Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
126 GNB5interactor80.179254.801WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Atg14 (PF10186, IPR018791): Vacuolar sorting 38 and autophagy-related subunit 14
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
WD40_like (PF17005, IPR031544): WD40-like domain
127 GNG10interactor50.3009.485G-gamma (PF00631, IPR015898, SM00224): GGL domain
128 GNG2interactor120.19789.230G-gamma (PF00631, IPR015898, SM00224): GGL domain
SidE (PF12252, IPR021014): Dot/Icm substrate protein
129 GNG4interactor60.20024.634G-gamma (PF00631, IPR015898, SM00224): GGL domain
130 GNG5interactor70.23829.217G-gamma (PF00631, IPR015898, SM00224): GGL domain
131 GPS1interactor300.526111.285RPN7 (PF10602, IPR019585): 26S proteasome subunit RPN7
PCI (PF01399, IPR000717, SM00088): PCI domain
132 GRK5protein found in more fusions290.193621.339Pkinase (PF00069, IPR000719): Protein kinase domain
RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain
133 GRWD1interactor170.56626.109Voldacs (PF03517): Regulator of volume decrease after cellular swelling
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex
134 H2AFVinteractor100.6442.162Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
135 HAX1interactor140.385224.657Mlf1IP (PF10248, IPR019376): Myelodysplasia-myeloid leukemia factor 1-interacting protein
136 HERC2interactor90.42922.742ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10)
Cyt-b5 (PF00173, IPR001199, SM01117): Cytochrome b5-like Heme/Steroid binding domain
MIB_HERC2 (PF06701, IPR010606): Mib_herc2
RCC1 (PF00415, IPR000408): Regulator of chromosome condensation (RCC1) repeat
zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box)
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7
Med3 (PF11593, IPR020998): Mediator complex subunit 3 fungal
RCC1_2 (PF13540): Regulator of chromosome condensation (RCC1) repeat
137 HIST1H1Ainteractor160.31730.671Mucin (PF01456, IPR000458): Mucin-like glycoprotein
Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family
CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal
138 HIST1H1Concoprotein220.51939.167Amelin (PF05111, IPR007798, SM00817): Ameloblastin precursor (Amelin)
Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family
DUF4349 (PF14257, IPR025645): Domain of unknown function (DUF4349)
139 HIST1H2ABinteractor130.6039.022Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
140 HIST1H2AEinteractor90.6947.462Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
141 HIST1H2AGinteractor110.6914.094Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
142 HIST1H2AIinteractor80.7860.161Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
143 HIST1H2AJinteractor80.7860.161Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
144 HIST1H2AKinteractor80.7860.161Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
145 HIST1H2ALinteractor80.7860.161Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
146 HIST1H2AMinteractor80.7860.161Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
147 HIST1H2BGoncoprotein90.36147.914Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
148 HIST1H3Ainteractor250.217160.634Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
149 HLA-Aoncoprotein80.46438.734DUF202 (PF02656, IPR003807): Domain of unknown function (DUF202)
MHC_I (PF00129, IPR001039): Class I Histocompatibility antigen, domains alpha 1 and 2
MHC_I_C (PF06623, IPR010579): MHC_I C-terminus
C1-set (PF07654, IPR003597, SM00407): Immunoglobulin C1-set domain
150 HNRNPA2B1oncoprotein310.56155.212RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
151 HNRNPABinteractor210.67618.762CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain
GRP (PF07172, IPR010800): Glycine rich protein family
NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
DUF2462 (PF09495, IPR019034): Protein of unknown function (DUF2462)
152 HNRNPDoncoprotein380.485131.657CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain
NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Keratin_2_head (PF16208, IPR032444): Keratin type II head
153 HNRNPDLinteractor280.63584.870CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
154 HNRNPFinteractor330.58358.183RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Spot_14 (PF07084, IPR009786): Thyroid hormone-inducible hepatic protein Spot 14
zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger
155 HNRNPH1oncoprotein360.55666.873RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger
156 HNRNPH3protein found in more fusions280.65831.096Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
157 HNRNPUL1interactor220.73843.969Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
Rox3 (PF08633, IPR013942): Rox3 mediator complex subunit
SAP (PF02037, IPR003034, SM00513): SAP domain
SPRY (PF00622, IPR003877, SM00449): SPRY domain
AAA_33 (PF13671): AAA domain
PRIMA1 (PF16101): Proline-rich membrane anchor 1
158 HOXA9oncoprotein31.0000Hox9_act (PF04617, IPR006711): Hox9 activation region
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
159 HOXB4interactor31.0000DUF4106 (PF13388, IPR025179): Protein of unknown function (DUF4106)
160 HSP90AA1oncoprotein730.2751488.401HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
161 HSP90AB1oncoprotein470.394269.058HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
162 HSP90B1suppressor210.47174.840CobT (PF06213, IPR006538): Cobalamin biosynthesis protein CobT
HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
Sigma70_ner (PF04546, IPR007631): Sigma-70, non-essential region
163 HSPA1Ainteractor340.55186.466HSP70 (PF00012, IPR013126): Hsp70 protein
164 HSPA1Binteractor170.54429.897HSP70 (PF00012, IPR013126): Hsp70 protein
165 HSPA1Linteractor240.489368.996HSP70 (PF00012, IPR013126): Hsp70 protein
166 HSPA5oncoprotein610.381592.873HSP70 (PF00012, IPR013126): Hsp70 protein
167 HSPA7interactor130.6672.104NA
168 HSPA8oncoprotein530.368480.462HSP70 (PF00012, IPR013126): Hsp70 protein
169 HSPA9oncoprotein360.383269.118HSP70 (PF00012, IPR013126): Hsp70 protein
170 HSPD1suppressor350.418179.648Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
171 IARSinteractor150.41938.824Anticodon_1 (PF08264, IPR013155): Anticodon-binding domain of tRNA
tRNA-synt_1 (PF00133, IPR002300): tRNA synthetases class I (I, L, M and V)
172 IFI16suppressor120.21259.782HIN (PF02760, IPR004021): HIN-200/IF120x domain
PYRIN (PF02758, IPR004020): PAAD/DAPIN/Pyrin domain
Mitofilin (PF09731, IPR019133): Mitochondrial inner membrane protein
173 IGF2BP1oncoprotein150.43818.182RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
KH_1 (PF00013, IPR004088, SM00322): KH domain
KH_4 (PF13083): KH domain
MOEP19 (PF16005, IPR031952): KH-like RNA-binding domain
174 IGHV3OR15-7interactor80.9640.018V-set (PF07686, IPR013106): Immunoglobulin V-set domain
175 IP6K1interactor50.9000.095IPK (PF03770, IPR005522): Inositol polyphosphate kinase
SIN1 (PF05422, IPR008828): Stress-activated map kinase interacting protein 1 (SIN1)
176 JAK3oncoprotein50.20048.317Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
177 KAT14oncoprotein41.0000Acetyltransf_10 (PF13673, IPR000182): Acetyltransferase (GNAT) domain
178 KAT2Ainteractor160.32446.492Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family
PCAF_N (PF06466, IPR009464): PCAF (P300/CBP-associated factor) N-terminal domain
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
NICE-1 (PF15845, IPR031698): Cysteine-rich C-terminal 1 family
179 KLHL9interactor61.0000BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
180 KRT1interactor180.66017.186Filament (PF00038, IPR001664): Intermediate filament protein
Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region
Keratin_2_head (PF16208, IPR032444): Keratin type II head
Keratin_2_tail (PF16210, IPR032449): Keratin type II cytoskeletal 1 tail
181 KRT10interactor140.74710.636Filament (PF00038, IPR001664): Intermediate filament protein
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
182 KRT2interactor190.53828.066Filament (PF00038, IPR001664): Intermediate filament protein
Keratin_2_head (PF16208, IPR032444): Keratin type II head
183 KRT24interactor90.9720.018Filament (PF00038, IPR001664): Intermediate filament protein
DUF4766 (PF15973, IPR031903): Domain of unknown function (DUF4766)
184 KRT75interactor100.9330.071Filament (PF00038, IPR001664): Intermediate filament protein
Keratin_2_head (PF16208, IPR032444): Keratin type II head
185 KRT76interactor70.9050.053Filament (PF00038, IPR001664): Intermediate filament protein
Keratin_2_head (PF16208, IPR032444): Keratin type II head
186 KRT9interactor130.70510.636Filament (PF00038, IPR001664): Intermediate filament protein
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
187 LAMTOR1interactor203.996LAMTOR (PF15454, IPR028209): Late endosomal/lysosomal adaptor and MAPK and MTOR activator
188 LGALS3BPoncoprotein270.63744.731BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
SRCR (PF00530, IPR001190): Scavenger receptor cysteine-rich domain
SRCR_2 (PF15494, IPR017448): Scavenger receptor cysteine-rich domain
189 LOC285556interactor100Apt1 (PF10351, IPR019443): Golgi-body localisation protein domain
DUF4585 (PF15232, IPR027838): Domain of unknown function (DUF4585)
190 LRWD1interactor60.6003.057WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
191 MAGED2interactor200.495185.388CDC27 (PF09507, IPR019038): DNA polymerase subunit Cdc27
MAGE (PF01454, IPR002190): MAGE family
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
DUF3306 (PF11748, IPR021735): Protein of unknown function (DUF3306)
192 MAP4oncoprotein100.46711.180SdiA-regulated (PF06977, IPR009722): SdiA-regulated
Tubulin-binding (PF00418, IPR001084): Tau and MAP protein, tubulin-binding repeat
DUF3275 (PF11679, IPR021693): Protein of unknown function (DUF3275)
193 MCM10interactor90.4729.240Mcm10 (PF09332, IPR015411): Mcm10 replication factor
zf-primase (PF09329, IPR015408): Primase zinc finger
AATF-Che1 (PF13339, IPR025160): Apoptosis antagonizing transcription factor
194 MCM2oncoprotein1030.1582406.077AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA)
MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
195 MDM2oncoprotein510.2691000.948Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region
Presenilin (PF01080, IPR001108): Presenilin
SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain
zf-FPG_IleRS (PF06827, IPR010663): Zinc finger found in FPG and IleRS
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
196 METAP2oncoprotein40.6670.425Peptidase_M24 (PF00557, IPR001714): Metallopeptidase family M24
SRP72 (PF08492, IPR013699): SRP72 RNA-binding domain
TSGP1 (PF07771, IPR011694): Tick salivary peptide group 1
197 MRPS11interactor70.6195.571Ribosomal_S11 (PF00411, IPR001971): Ribosomal protein S11
198 MTM1interactor100GRAM (PF02893, IPR004182, SM00568): GRAM domain
Myotub-related (PF06602, IPR010569): Myotubularin-like phosphatase domain
3-PAP (PF12578, IPR022587): Myotubularin-associated protein
199 MYBoncoprotein90.4177.384Cmyb_C (PF09316, IPR015395): C-myb, C-terminal
LMSTEN (PF07988, IPR012642): LMSTEN motif
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
200 MYConcoprotein440.196793.150HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain
Myc_N (PF01056, IPR012682): Myc amino-terminal region
201 MYH9suppressor230.332612.877IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain
Myosin_tail_1 (PF01576, IPR002928): Myosin tail
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
202 NACC1interactor40.3332.535BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
BEN (PF10523, IPR018379, SM01025): BEN domain
203 NANOGinteractor190.18355.482Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
204 NCLprotein found in more fusions390.448126.493DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754)
Myc_N (PF01056, IPR012682): Myc amino-terminal region
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
YL1 (PF05764, IPR008895): YL1 nuclear protein
Limkain-b1 (PF11608, IPR024582): Limkain b1
205 NEDD8interactor980.2091044.368ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
206 NF2suppressor250.149670.346ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain
FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
207 NFKB1suppressor170.55824.264Death (PF00531, IPR000488, SM00005): Death domain
GHMP_kinases_C (PF08544, IPR013750): GHMP kinases C terminal
RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
208 NPM1suppressor640.352931.779Nucleoplasmin (PF03066): Nucleoplasmin/nucleophosmin domain
SDA1 (PF05285, IPR007949): SDA1
NPM1-C (PF16276, IPR032569): Nucleophosmin C-terminal domain
209 NTRK1oncoprotein1170.1665202.526I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
210 NUCB1interactor50.20038.414DUF1104 (PF06518, IPR009488): Protein of unknown function (DUF1104)
Spc24 (PF08286, IPR013252): Spc24 subunit of Ndc80
DUF2967 (PF11179, IPR021349): Protein of unknown function (DUF2967)
DUF3552 (PF12072, IPR022711): Domain of unknown function (DUF3552)
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
211 NUCB2interactor30.6675.098Bap31 (PF05529, IPR008417): B-cell receptor-associated protein 31-like
Histone_HNS (PF00816, IPR001801): H-NS histone family
Peptidase_U57 (PF05582, IPR008764): YabG peptidase U57
Put_DNA-bind_N (PF06971, IPR009718): Putative DNA-binding protein N-terminus
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
212 NUP43interactor40.6671.206WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
213 NXPH3interactor21.0000Neurexophilin (PF06312, IPR026845): Neurexophilin
214 OCIAD1interactor70.33313.279OCIA (PF07051, IPR009764): Ovarian carcinoma immunoreactive antigen (OCIA)
215 OPTNprotein found in more fusions50.33310.364ARD (PF03079, IPR004313): ARD/ARD' family
bZIP_1 (PF00170, IPR004827): bZIP transcription factor
HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region
NEMO (PF11577, IPR021063): NF-kappa-B essential modulator NEMO
CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator
216 OTULINinteractor31.0000Peptidase_C101 (PF16218, IPR023235): Peptidase family C101
217 PABPC1oncoprotein330.524189.758RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain
YflT (PF11181, IPR025889): Heat induced stress protein YflT
218 PABPC4interactor210.61032.479ApbA_C (PF08546, IPR013752): Ketopantoate reductase PanE/ApbA C terminal
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain
HHV-5_US34A (PF17087, IPR031384): Herpesvirus US34A protein family
219 PAICSinteractor100.33364.493AIRC (PF00731, IPR000031, SM01001): AIR carboxylase
SAICAR_synt (PF01259, IPR028923): SAICAR synthetase
220 PANX1interactor2010.532Innexin (PF00876, IPR000990): Innexin
Pannexin_like (PF12534, IPR021040): Pannexin-like TM region of LRRC8
221 PCBD1protein found in more fusions100.7781.616Pterin_4a (PF01329, IPR001533): Pterin 4 alpha carbinolamine dehydratase
222 PCK1interactor150.219140.318PEPCK (PF00821, IPR008209): Phosphoenolpyruvate carboxykinase
223 PCNAoncoprotein270.41872.598PCNA_C (PF02747, IPR022649): Proliferating cell nuclear antigen, C-terminal domain
PCNA_N (PF00705, IPR022648): Proliferating cell nuclear antigen, N-terminal domain
224 PFASinteractor80.42916.266AIRS_C (PF02769, IPR010918): AIR synthase related protein, C-terminal domain
GATase_5 (PF13507): CobB/CobQ-like glutamine amidotransferase domain
225 PHIPoncoprotein90.5287.782DTHCT (PF08070, IPR012542): DTHCT (NUC029) region
DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764)
E7 (PF00527, IPR000148): E7 protein, Early protein
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
226 POC1Binteractor31.0000WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
227 POU5F1oncoprotein300.175136.642Pou (PF00157, IPR000327, SM00352): Pou domain - N-terminal to homeobox domain
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
228 PPP2R1Aoncoprotein230.45146.763TAF6_C (PF07571, IPR011442): TAF6 C-terminal HEAT repeat domain
HEAT (PF02985, IPR000357): HEAT repeat
HEAT_PBS (PF03130, IPR004155, SM00567): PBS lyase HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
229 PRDX1oncoprotein220.443195.496AhpC-TSA (PF00578, IPR000866): AhpC/TSA family
1-cysPrx_C (PF10417, IPR019479): C-terminal domain of 1-Cys peroxiredoxin
230 PRMT5protein found in more fusions190.333162.929PRMT5 (PF05185, IPR025799): PRMT5 arginine-N-methyltransferase
231 PSMC6interactor130.40914.206AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
AAA_2 (PF07724, IPR013093): AAA domain (Cdc48 subfamily)
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
Prot_ATP_ID_OB (PF16450, IPR032501): Proteasomal ATPase OB/ID domain
232 PTGIRinteractor41.00007tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
233 PTGS2oncoprotein120.56477.541An_peroxidase (PF03098, IPR002007): Animal haem peroxidase
EGF (PF00008, IPR000742, SM00181): EGF-like domain
234 PWP1interactor130.6679.361WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
235 PYGO2interactor90.6077.017PHD (PF00628, IPR019787, SM00249): PHD-finger
236 QPCTinteractor90.9440.043Peptidase_M28 (PF04389, IPR007484): Peptidase family M28
237 RAD21oncoprotein250.42737.093Rad21_Rec8 (PF04824, IPR006909): Conserved region of Rad21 / Rec8 like protein
Rad21_Rec8_N (PF04825, IPR006910): N terminus of Rad21 / Rec8 like protein
FAM176 (PF14851): FAM176 family
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
238 RAG1interactor80.6192.719zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
zf-RAG1 (PF10426, IPR019485): Recombination-activating protein 1 zinc-finger domain
RAG1_imp_bd (PF12560): RAG1 importin binding
RAG1 (PF12940, IPR024627): Recombination-activation protein 1 (RAG1), recombinase
239 RASSF1suppressor110.6007.896RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
Nore1-SARAH (PF16517, IPR011524): Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain
240 RBBP4oncoprotein170.42649.804eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein
CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex
241 RBBP5oncoprotein120.45516.372WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457)
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
242 RBBP7suppressor140.38540.167WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein
CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex
243 RBX1oncoprotein540.274526.264zf-rbx1 (PF12678, IPR024766): RING-H2 zinc finger domain
244 RFWD2suppressor280.58737.368Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein
IncA (PF04156, IPR007285): IncA protein
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
WD40_like (PF17005, IPR031544): WD40-like domain
245 RGS12interactor21.0000PT-HINT (PF07591): Pretoxin HINT domain
GoLoco (PF02188, IPR003109, SM00390): GoLoco motif
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID)
RBD (PF02196, IPR003116, SM00455): Raf-like Ras-binding domain
RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain
RGS12_us2 (PF16611): Unstructured region between RBD and GoLoco
RGS12_usC (PF16612): C-terminal unstructured region of RGS12
RGS12_us1 (PF16613): Unstructured region of RGS12
246 RGS2oncoprotein60.33367.030RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain
247 RIC8Binteractor30.6673.925Ric8 (PF10165, IPR019318): Guanine nucleotide exchange factor synembryn
248 RNF7oncoprotein150.49519.883zf-rbx1 (PF12678, IPR024766): RING-H2 zinc finger domain
Prok-RING_1 (PF14446): Prokaryotic RING finger family 1
249 RPL10Ainteractor380.62464.902Ribosomal_L1 (PF00687, IPR028364): Ribosomal protein L1p/L10e family
250 RPL11suppressor390.64053.506Ribosomal_L5 (PF00281, IPR002132): Ribosomal protein L5
Ribosomal_L5_C (PF00673, IPR002132): ribosomal L5P family C-terminus
251 RPL15interactor380.67052.000Ribosomal_L15e (PF00827, IPR000439): Ribosomal L15
252 RPL19interactor310.74023.776DUF1682 (PF07946, IPR012879): Protein of unknown function (DUF1682)
Ribosomal_L19e (PF01280, IPR000196): Ribosomal protein L19e
253 RPL22oncoprotein360.546100.952Ribosomal_L22e (PF01776, IPR002671): Ribosomal L22e protein family
254 RPL23Ainteractor360.67840.521Ribosomal_L23 (PF00276, IPR013025): Ribosomal protein L23
Ribosomal_L23eN (PF03939, IPR005633): Ribosomal protein L23, N-terminal domain
255 RPL26oncoprotein160.7922.882TP2 (PF01254, IPR000678): Nuclear transition protein 2
Ribosomal_L26 (PF16906, IPR005756): Ribosomal proteins L26 eukaryotic, L24P archaeal
256 RPL38interactor310.66049.779Ribosomal_L38e (PF01781, IPR002675): Ribosomal L38e protein family
257 RPL4interactor450.522227.710Ribosomal_L4 (PF00573, IPR002136): Ribosomal protein L4/L1 family
Ribos_L4_asso_C (PF14374, IPR025755): 60S ribosomal protein L4 C-terminal domain
258 RPL7Aprotein found in more fusions330.62145.851Ribosomal_L7Ae (PF01248, IPR004038): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
259 RPL7AP27interactor100.8000.532NA
260 RPLP1interactor300.77830.683Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
261 RPLP2protein found in more fusions350.69026.988Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
262 RPS14interactor390.59596.503Ribosomal_S11 (PF00411, IPR001971): Ribosomal protein S11
263 RPS15Ainteractor390.560101.048Ribosomal_S8 (PF00410, IPR000630): Ribosomal protein S8
264 RPS18protein found in more fusions320.67545.411Ribosomal_S13 (PF00416, IPR001892): Ribosomal protein S13/S18
265 RPS2interactor440.502655.657Ribosomal_S5 (PF00333, IPR013810): Ribosomal protein S5, N-terminal domain
Ribosomal_S5_C (PF03719, IPR005324): Ribosomal protein S5, C-terminal domain
266 RPS20interactor330.70632.558Ribosomal_S10 (PF00338, IPR027486): Ribosomal protein S10p/S20e
267 RPS3interactor460.500177.257KH_2 (PF07650, IPR004044): KH domain
Ribosomal_S3_C (PF00189, IPR001351): Ribosomal protein S3, C-terminal domain
268 RPTORprotein found in more fusions90.46477.264HEAT (PF02985, IPR000357): HEAT repeat
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
HEAT_2 (PF13646): HEAT repeats
Raptor_N (PF14538, IPR029347): Raptor N-terminal CASPase like domain
269 RUVBL1oncoprotein250.373200.940TIP49 (PF06068, IPR010339): TIP49 C-terminus
270 SALL2suppressor70.6192.793CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
MPP6 (PF10175, IPR019324): M-phase phosphoprotein 6
zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding
Astro_capsid_p (PF12226, IPR022027): Turkey astrovirus capsid protein
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger
271 SAMHD1protein found in more fusions140.60311.316HD (PF01966, IPR006674): HD domain
SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
272 SAP130interactor100.5117.151SAP130_C (PF16014, IPR031963): Histone deacetylase complex subunit SAP130 C-terminus
273 SCAF11interactor80.3937.658DUF566 (PF04484, IPR007573): Family of unknown function (DUF566)
Phage_XkdX (PF09693, IPR010022): Phage uncharacterised protein (Phage_XkdX)
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834)
274 SDHAsuppressor120.9090.557FAD_binding_2 (PF00890, IPR003953): FAD binding domain
Succ_DH_flav_C (PF02910, IPR015939): Fumarate reductase flavoprotein C-term
275 SENP8interactor60.8000.517Peptidase_C48 (PF02902, IPR003653): Ulp1 protease family, C-terminal catalytic domain
276 SF3B3interactor230.49442.375CPSF_A (PF03178, IPR004871): CPSF A subunit region
MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term
277 SFXN1interactor40.5001.591Mtc (PF03820, IPR004686): Tricarboxylate carrier
278 SH3RF2interactor21.0000SH3_2 (PF07653, IPR011511): Variant SH3 domain
TUDOR (PF00567, IPR002999, SM00333): Tudor domain
UPF0547 (PF10571, IPR018886): Uncharacterised protein family UPF0547
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
SH3_9 (PF14604, IPR001452): Variant SH3 domain
279 SHMT2interactor150.362280.125SHMT (PF00464, IPR001085): Serine hydroxymethyltransferase
280 SKP1oncoprotein370.338192.072Skp1 (PF01466, IPR016072, SM00512): Skp1 family, dimerisation domain
Skp1_POZ (PF03931, IPR016073): Skp1 family, tetramerisation domain
281 SKP2suppressor220.46848.355LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
LRR_2 (PF07723, IPR013101): Leucine Rich Repeat
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
F-box-like (PF12937, IPR001810): F-box-like
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
LRR_8 (PF13855, IPR001611): Leucine rich repeat
282 SLAinteractor201.223SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
283 SLC25A12interactor3016.440Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
EF-hand_1 (PF00036, IPR002048, SM00054): EF hand
EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
284 SLC25A22interactor50.5004.417Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
DUF4257 (PF14074, IPR025353): Protein of unknown function (DUF4257)
285 SLC25A5interactor300.63048.032Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
286 SLC25A6interactor140.40738.832Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
287 SNRNP40interactor70.5246.401WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
288 SNRNP70interactor240.56240.545RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
289 SNRPAinteractor180.64012.967RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
290 SNRPBinteractor130.7566.178LSM (PF01423, IPR001163): LSM domain
291 SNRPD1interactor310.48476.793API5 (PF05918, IPR008383): Apoptosis inhibitory protein 5 (API5)
LSM (PF01423, IPR001163): LSM domain
292 SNRPD3interactor200.56325.288LSM (PF01423, IPR001163): LSM domain
293 SNRPEinteractor170.69914.030LSM (PF01423, IPR001163): LSM domain
294 SNX13interactor100DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
Nexin_C (PF08628, IPR013937): Sorting nexin C terminal
PX (PF00787, IPR001683, SM00312): PX domain
PXA (PF02194, IPR003114, SM00313): PXA domain
RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain
Swi3 (PF07962, IPR012923): Replication Fork Protection Component Swi3
DUF2314 (PF10077, IPR018756): Uncharacterized protein conserved in bacteria (DUF2314)
295 SRSF3oncoprotein200.51679.784DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
296 SSBP1interactor230.50642.697SSB (PF00436, IPR000424): Single-strand binding protein family
297 SUGT1interactor110.45515.972CheC (PF04509, IPR007597): CheC-like family
CS (PF04969, IPR007052): CS domain
SGS (PF05002, IPR007699): SGS domain
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
TPR_16 (PF13432): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
298 SYNMsuppressor21.0000Filament (PF00038, IPR001664): Intermediate filament protein
CCDC-167 (PF15188, IPR028194): Coiled-coil domain-containing protein 167
299 SYNPOinteractor70.5713.891Calsarcin (PF05556, IPR008438): Calcineurin-binding protein (Calsarcin)
300 TAF15oncoprotein160.6258.977API5 (PF05918, IPR008383): Apoptosis inhibitory protein 5 (API5)
GRP (PF07172, IPR010800): Glycine rich protein family
Presenilin (PF01080, IPR001108): Presenilin
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
301 TBXA2Rinteractor90.35766.4717tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
302 TCHPsuppressor21.0000TAF8_C (PF10406, IPR019473): Transcription factor TFIID complex subunit 8 C-term
TPH (PF13868): Trichohyalin-plectin-homology domain
PNRC (PF15365, IPR028322): Proline-rich nuclear receptor coactivator
303 TFGoncoprotein220.60525.099ARS2 (PF04959, IPR007042): Arsenite-resistance protein 2
MucBP (PF06458, IPR009459): MucBP domain
PB1 (PF00564, IPR000270, SM00666): PB1 domain
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
304 THOC2interactor60.46722.277Sec62 (PF03839, IPR004728): Translocation protein Sec62
Tho2 (PF11262, IPR021418): Transcription factor/nuclear export subunit protein 2
Thoc2 (PF11732, IPR021726): Transcription- and export-related complex subunit
DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915)
THOC2_N (PF16134, IPR032302): THO complex subunit 2 N-terminus
305 TIA1interactor130.56414.310Calcipressin (PF04847, IPR006931): Calcipressin
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PHM7_cyt (PF14703, IPR027815): Cytosolic domain of 10TM putative phosphate transporter
306 TIAL1interactor140.56014.496RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
307 TLE2protein found in more fusions31.0000TLE_N (PF03920, IPR005617): Groucho/TLE N-terminal Q-rich domain
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
WD40_like (PF17005, IPR031544): WD40-like domain
308 TOR1AIP2interactor100.8890.622LAP1C (PF05609, IPR008662): Lamina-associated polypeptide 1C (LAP1C)
309 TP53suppressor940.1722101.265DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
P53 (PF00870, IPR011615): P53 DNA-binding domain
P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
310 TROinteractor40.16714.118MAGE (PF01454, IPR002190): MAGE family
DUF3533 (PF12051, IPR022703): Protein of unknown function (DUF3533)
AP3D1 (PF06375): AP-3 complex subunit delta-1
311 TRPC4APinteractor70.8101.307Put_DNA-bind_N (PF06971, IPR009718): Putative DNA-binding protein N-terminus
DUF3689 (PF12463, IPR022162): Protein of unknown function (DUF3689)
312 TTC1interactor80.28698.751TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat
313 TUBA1Bprotein found in more fusions110.40014.559Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
314 TUBA1Cprotein found in more fusions380.401670.012Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
315 TUBA4Ainteractor290.490311.095Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
316 TUBA4Binteractor100.8220.823Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
317 TUBBprotein found in more fusions440.420217.969Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
318 TUBB1interactor120.545131.810Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
319 TUBB4Binteractor330.48579.185Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
320 TUBG1protein found in more fusions480.281361.959Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
321 UBCprotein found in more fusions780.2222263.776ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
322 UBE2E3protein found in more fusions110.6894.758UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
323 UBXN7interactor160.55824.607UBX (PF00789, IPR001012, SM00166): UBX domain
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
Thioredoxin_7 (PF13899): Thioredoxin-like
UBA_4 (PF14555): UBA-like domain
324 UNKinteractor280.217208.319MbeD_MobD (PF04899, IPR006983): MbeD/MobD like
NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region
zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
zf-CCCH_2 (PF14608): RNA-binding, Nab2-type zinc finger
Torus (PF16131, IPR032297): Torus domain
325 USP7oncoprotein320.303395.197MATH (PF00917, IPR002083, SM00061): MATH domain
UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
USP7_ICP0_bdg (PF12436, IPR024729): ICP0-binding domain of Ubiquitin-specific protease 7
USP7_C2 (PF14533, IPR029346): Ubiquitin-specific protease C-terminal
326 VCPprotein found in more fusions600.251942.995AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2
CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain
TniB (PF05621, IPR008868): Bacterial TniB protein
Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain
DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944)
327 VIPR1interactor21.00007tm_2 (PF00002, IPR000832): 7 transmembrane receptor (Secretin family)
HRM (PF02793, IPR001879, SM00008): Hormone receptor domain
328 WDR26interactor110.43682.852eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
329 WDR5interactor280.275229.834WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
330 WDR5Binteractor31.0000WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
331 WDR61interactor90.47214.107WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
332 WDR76interactor120.37927.921WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
SPATIAL (PF15256): SPATIAL
333 WDR82oncoprotein110.52714.678MinC_C (PF03775, IPR005526): Septum formation inhibitor MinC, C-terminal domain
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Frtz (PF11768, IPR024511): WD repeat-containing and planar cell polarity effector protein Fritz
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
334 WDTC1interactor70.47614.487WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
TPR_6 (PF13174, IPR019734): Tetratricopeptide repeat
335 WSB1interactor41.0000PD40 (PF07676, IPR011659): WD40-like Beta Propeller Repeat
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
SOCS_box (PF07525, IPR001496): SOCS box
336 WSB2interactor40.8330.120PD40 (PF07676, IPR011659): WD40-like Beta Propeller Repeat
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
SOCS_box (PF07525, IPR001496): SOCS box
337 XPO1interactor690.1092747.603CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
338 XXYLT1oncoprotein204.939Glyco_transf_8 (PF01501, IPR002495): Glycosyl transferase family 8
339 YBEYinteractor30.3335.208UPF0054 (PF02130, IPR002036): Uncharacterized protein family UPF0054
340 ZNF407interactor21.0000AKAP95 (PF04988, IPR007071): A-kinase anchoring protein 95 (AKAP95)
zf-BED (PF02892, IPR003656, SM00614): BED zinc finger
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding
zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies)
zf-met (PF12874): Zinc-finger of C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zinc_ribbon_4 (PF13717): zinc-ribbon domain
zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain
341 ZNF525interactor21.0000KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger

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