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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)100
The number (and %) of the onco-proteins14 (14.00 %)
The number (and %) of the tumor suppressors7 (7.00 %)
Total number of binary PPIs (saturation %)395 (7.98 %)
The number (and %) of affected PPIs99 (25.06 %)
The number of possible different fusions8
PPI diameter5
PPI radius3
The average degree of PPI7.440
Assortativity coefficient-0.2184
The network average Clustering coefficient0.436
The number (and %) of a zero Clustering coefficients20 (20.00 %)
The number (and %) of a zero Betweenness Centrality28 (28.00 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: RPS6KA6,WDR12 All fusions
Proteins found in more fusions APP (see 4 fusions); GRK5 (see 4 fusions); TSN (see 1 fusions); HSP90AA1 (see 3 fusions); BOP1 (see 1 fusions); RXRA (see 2 fusions); CDC37 (see 2 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 RPS6KA6parental protein360.0323152.035Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
2 WDR12parental protein630.1043483.373NLE (PF08154, IPR012972): NLE (NUC135) domain
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
3 ACBD3interactor50.7001.667ACBP (PF00887, IPR000582): Acyl CoA binding protein
CDC45 (PF02724, IPR003874): CDC45-like protein
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
GOLD_2 (PF13897, IPR009038): Golgi-dynamics membrane-trafficking
NINJA_B (PF16136, IPR032310): Putative nuclear localisation signal
4 ADIRFinteractor100Apolipoprotein (PF01442, IPR000074): Apolipoprotein A1/A4/E domain
5 APPprotein found in more fusions250.1051339.958APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding
Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP)
BUD22 (PF09073, IPR015158): BUD22
IncA (PF04156, IPR007285): IncA protein
Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus
APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
6 BMI1oncoprotein120.27375.278zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
7 BOP1oncoprotein110.46721.100BOP1NT (PF08145, IPR012953, SM01035): BOP1NT (NUC169) domain
Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP)
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
DUF3038 (PF11237, IPR021399): Protein of unknown function (DUF3038)
Frtz (PF11768, IPR024511): WD repeat-containing and planar cell polarity effector protein Fritz
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
8 BRIX1interactor140.72513.539Brix (PF04427, IPR007109, SM00879): Brix domain
9 BTRConcoprotein80.42932.316WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
F-box-like (PF12937, IPR001810): F-box-like
10 BYSLinteractor80.53641.967Bystin (PF05291, IPR007955): Bystin
MEA1 (PF06910, IPR009685): Male enhanced antigen 1 (MEA1)
11 C14orf1interactor30.33363.762Erg28 (PF03694, IPR005352): Erg28 like protein
12 CASQ2interactor31.0000Calsequestrin (PF01216, IPR001393): Calsequestrin
SDA1 (PF05285, IPR007949): SDA1
13 CDC37protein found in more fusions90.321194.467CDC37_C (PF08564, IPR013873, SM01069): Cdc37 C terminal domain
CDC37_M (PF08565, IPR013874, SM01070): Cdc37 Hsp90 binding domain
CDC37_N (PF03234, IPR013855, SM01071): Cdc37 N terminal kinase binding
Rho_Binding (PF08912, IPR015008): Rho Binding
TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
14 CEBPZinteractor70.524229.086BRF1 (PF07741, IPR011665): Brf1-like TBP-binding domain
CBF (PF03914, IPR005612, SM00521): CBF/Mak21 family
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
15 CENPBinteractor50.50066.377CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain
CENP-B_N (PF04218, IPR007889): CENP-B N-terminal DNA-binding domain
DDE_1 (PF03184, IPR004875): DDE superfamily endonuclease
K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
RNA_polI_A34 (PF08208, IPR013240): DNA-directed RNA polymerase I subunit RPA34.5
Sporozoite_P67 (PF05642, IPR008845): Sporozoite P67 surface antigen
HTH_Tnp_Tc5 (PF03221, IPR006600, SM00674): Tc5 transposase DNA-binding domain
16 CHMP7interactor40.8330.667Snf7 (PF03357, IPR005024): Snf7
17 CLEC3Binteractor21.0000Chordopox_A33R (PF05966, IPR009238): Chordopoxvirus A33R protein
Ribosomal_L29 (PF00831, IPR001854): Ribosomal L29 protein
Lectin_C (PF00059, IPR001304, SM00034): Lectin C-type domain
18 CSNK2Binteractor130.197378.411CK_II_beta (PF01214, IPR000704, SM01085): Casein kinase II regulatory subunit
19 DDX19Ainteractor31.0000DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
20 DDX24interactor180.536152.288DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain
Sec62 (PF03839, IPR004728): Translocation protein Sec62
Tti2 (PF10521, IPR018870): Tti2 family
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
21 DDX27interactor90.8331.789Asp-B-Hydro_N (PF05279, IPR007943): Aspartyl beta-hydroxylase N-terminal region
DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
MAP17 (PF15807, IPR031627): Membrane-associated protein 117 kDa, PDZK1-interacting protein 1
22 DDX54interactor50.70013.442DBP10CT (PF08147, IPR012541, SM01123): DBP10CT (NUC160) domain
DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Herpes_DNAp_acc (PF04929, IPR007013): Herpes DNA replication accessory factor
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
23 DDX6oncoprotein31.0000DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
24 DHX34interactor100DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold
HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2)
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
25 DNAJC13interactor100Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
Arm_2 (PF04826, IPR006911): Armadillo-like
DUF4339 (PF14237, IPR025640): Domain of unknown function (DUF4339)
26 DNMT1suppressor4045.586BAH (PF01426, IPR001025, SM00439): BAH domain
DMAP_binding (PF06464, IPR010506, SM01137): DMAP1-binding Domain
DNA_methylase (PF00145, IPR001525): C-5 cytosine-specific DNA methylase
zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain
DNMT1-RFD (PF12047, IPR022702): Cytosine specific DNA methyltransferase replication foci domain
27 EBNA1BP2interactor130.75623.205Ebp2 (PF05890, IPR008610): Eukaryotic rRNA processing protein EBP2
28 FBN3interactor100EGF (PF00008, IPR000742, SM00181): EGF-like domain
EGF_2 (PF07974, IPR013111): EGF-like domain
EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain
TB (PF00683, IPR017878): TB domain
hEGF (PF12661, IPR013032): Human growth factor-like EGF
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site
29 FBXW11interactor100.30699.017WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
F-box-like (PF12937, IPR001810): F-box-like
30 FTSJ3interactor140.67015.098DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764)
FtsJ (PF01728, IPR002877): FtsJ-like methyltransferase
M16C_assoc (PF08367, IPR013578): Peptidase M16C associated
Orthopox_F8 (PF05886, IPR008726): Orthopoxvirus F8 protein
Spb1_C (PF07780, IPR012920): Spb1 C-terminal domain
DUF3381 (PF11861, IPR024576): Domain of unknown function (DUF3381)
RRP14 (PF15459, IPR029188): 60S ribosome biogenesis protein Rrp14
31 FZD5interactor100Frizzled (PF01534, IPR000539): Frizzled/Smoothened family membrane region
Fz (PF01392, IPR020067, SM00063): Fz domain
32 GRK5protein found in more fusions80.38180.190Pkinase (PF00069, IPR000719): Protein kinase domain
RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain
33 GTPBP4suppressor130.70523.353DUF258 (PF03193, IPR004881): Protein of unknown function, DUF258
MRC1 (PF09444, IPR018564): MRC1-like domain
NOG1 (PF06858, IPR010674): Nucleolar GTP-binding protein 1 (NOG1)
NOGCT (PF08155, IPR012973): NOGCT (NUC087) domain
Lip_prot_lig_C (PF10437, IPR019491): Bacterial lipoate protein ligase C-terminus
AAA_16 (PF13191): AAA ATPase domain
34 HIST1H1Concoprotein40.6671.667Amelin (PF05111, IPR007798, SM00817): Ameloblastin precursor (Amelin)
Linker_histone (PF00538, IPR005818, SM00526): linker histone H1 and H5 family
DUF4349 (PF14257, IPR025645): Domain of unknown function (DUF4349)
35 HNRNPDLinteractor40.6671.357CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
36 HSP90AA1oncoprotein120.182363.858HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
37 IFI16suppressor220.286436.952HIN (PF02760, IPR004021): HIN-200/IF120x domain
PYRIN (PF02758, IPR004020): PAAD/DAPIN/Pyrin domain
Mitofilin (PF09731, IPR019133): Mitochondrial inner membrane protein
38 INPP1interactor100Inositol_P (PF00459, IPR000760): Inositol monophosphatase family
39 KMT2Einteractor21.0000CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
PHD (PF00628, IPR019787, SM00249): PHD-finger
SET (PF00856, IPR001214, SM00317): SET domain
MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
DUF4124 (PF13511, IPR025392): Domain of unknown function (DUF4124)
PHD_3 (PF13922, IPR026905): PHD domain of transcriptional enhancer, Asx
DUF4666 (PF15697, IPR031421): Domain of unknown function (DUF4666)
PRIMA1 (PF16101): Proline-rich membrane anchor 1
40 LMO4interactor208.934LIM (PF00412, IPR001781, SM00132): LIM domain
zf-dskA_traR (PF01258, IPR000962): Prokaryotic dksA/traR C4-type zinc finger
41 MAPK3oncoprotein50.33379.729Pkinase (PF00069, IPR000719): Protein kinase domain
42 MASP1interactor21.0000CUB (PF00431, IPR000859, SM00042): CUB domain
Sushi (PF00084, IPR000436, SM00032): Sushi repeat (SCR repeat)
Trypsin (PF00089, IPR001254, SM00020): Trypsin
FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site
43 MBPinteractor21.0000Myelin_MBP (PF01669, IPR000548): Myelin basic protein
44 MDN1interactor50.7002.192AAA_5 (PF07728, IPR011704): AAA domain (dynein-related subfamily)
DNA_pol_phi (PF04931, IPR007015): DNA polymerase phi
DnaB_C (PF03796, IPR007694): DnaB-like helicase C terminal domain
AAA_16 (PF13191): AAA ATPase domain
Sigma54_activ_2 (PF14532, IPR002078): Sigma-54 interaction domain
45 MED24interactor30.6673.956Med24_N (PF11277, IPR021429): Mediator complex subunit 24 N-terminal
46 MICAL1interactor100CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
DAO (PF01266, IPR006076): FAD dependent oxidoreductase
FAD_binding_3 (PF01494, IPR002938): FAD binding domain
LIM (PF00412, IPR001781, SM00132): LIM domain
DUF3585 (PF12130, IPR022735): Protein of unknown function (DUF3585)
NAD_binding_7 (PF13241, IPR006367): Putative NAD(P)-binding
47 MPP1oncoprotein100PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
SH3_2 (PF07653, IPR011511): Variant SH3 domain
Guanylate_kin (PF00625, IPR008145, SM00072): Guanylate kinase
P33MONOX (PF15302, IPR026759): P33 mono-oxygenase
48 MRTO4interactor140.61520.924Glu_syn_central (PF04898, IPR006982): Glutamate synthase central domain
Ribosomal_L10 (PF00466, IPR001790): Ribosomal protein L10
49 NFYAinteractor21.0000CBFB_NFYA (PF02045, IPR001289): CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B
MSP1_C (PF07462, IPR010901): Merozoite surface protein 1 (MSP1) C-terminus
FixG_C (PF11614, IPR032879): IG-like fold at C-terminal of FixG, putative oxidoreductase
DUF4237 (PF14021, IPR025331): Protein of unknown function (DUF4237)
50 NIFKinteractor150.71411.792RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
hNIFK_binding (PF12196, IPR021043): FHA Ki67 binding domain of hNIFK
51 NOC3Linteractor90.8061.642CBF (PF03914, IPR005612, SM00521): CBF/Mak21 family
Cytochrom_B562 (PF07361, IPR009155): Cytochrome b562
DsrD (PF08679, IPR014793): Dissimilatory sulfite reductase D (DsrD)
GAGA_bind (PF06217, IPR010409): GAGA binding protein-like family
NOC3p (PF07540, IPR011501): Nucleolar complex-associated protein
Scm3 (PF10384, IPR018465): Centromere protein Scm3
52 NR4A1suppressor50.100123.702zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
53 OSGIN1suppressor100Pyr_redox_2 (PF07992, IPR023753): Pyridine nucleotide-disulphide oxidoreductase
Pyr_redox_3 (PF13738): Pyridine nucleotide-disulphide oxidoreductase
54 PES1interactor200.556154.239Pescadillo_N (PF06732, IPR010613): Pescadillo N-terminus
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
DUF3347 (PF11827, IPR021782): Protein of unknown function (DUF3347)
U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain
55 PPP2CBsuppressor30.33310.877Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
56 PPP3CBinteractor50.7002.500CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
PRIMA1 (PF16101): Proline-rich membrane anchor 1
57 PQBP1interactor30.6677.441WW (PF00397, IPR001202, SM00456): WW domain
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
58 PSPC1interactor30.6670.750FUSC (PF04632, IPR006726): Fusaric acid resistance protein family
NOPS (PF08075, IPR012975): NOPS (NUC059) domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Zot (PF05707, IPR008900): Zonular occludens toxin (Zot)
59 PUS1interactor40.6671.810PseudoU_synth_1 (PF01416, IPR020097): tRNA pseudouridine synthase
60 RBPJinteractor40.167118.177BTD (PF09270, IPR015350): Beta-trefoil DNA-binding domain
LAG1-DNAbind (PF09271, IPR015351): LAG1, DNA binding
TIG (PF01833, IPR002909): IPT/TIG domain
61 RNF2interactor260.270357.099zf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
62 RPL36interactor80.53642.660Ribosomal_L36e (PF01158, IPR000509): Ribosomal protein L36e
63 RPL4interactor150.56242.559Ribosomal_L4 (PF00573, IPR002136): Ribosomal protein L4/L1 family
Ribos_L4_asso_C (PF14374, IPR025755): 60S ribosomal protein L4 C-terminal domain
64 RPL7interactor150.419119.199Ribosomal_L30 (PF00327, IPR016082): Ribosomal protein L30p/L7e
Ribosomal_L30_N (PF08079, IPR012988): Ribosomal L30 N-terminal domain
65 RPLP1interactor90.321234.899Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
66 RPUSD2interactor50.60055.656PseudoU_synth_2 (PF00849, IPR006145): RNA pseudouridylate synthase
67 RTCBinteractor60.4677.362RtcB (PF01139, IPR001233): tRNA-splicing ligase RtcB
68 RXRAoncoprotein70.33327.637zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
Nuc_recep-AF1 (PF11825, IPR021780): Nuclear/hormone receptor activator site AF-1
69 SAP30BPinteractor100Dicty_REP (PF05086, IPR007778): Dictyostelium (Slime Mold) REP protein
HCNGP (PF07818, IPR012479): HCNGP-like protein
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
70 SEPHS1interactor80.381115.933AIRS (PF00586, IPR000728): AIR synthase related protein, N-terminal domain
AIRS_C (PF02769, IPR010918): AIR synthase related protein, C-terminal domain
71 SIRT7interactor250.297397.007DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563)
SIR2 (PF02146, IPR003000): Sir2 family
72 SLC9A1interactor100DUF1427 (PF07235, IPR009872): Protein of unknown function (DUF1427)
LHC (PF00556, IPR000066): Antenna complex alpha/beta subunit
Na_H_Exchanger (PF00999, IPR006153): Sodium/hydrogen exchanger family
NEXCaM_BD (PF16644, IPR032103): Regulatory region of Na+/H+ exchanger NHE binds to calmodulin
73 SNF8interactor70.6005.140EAP30 (PF04157, IPR007286): EAP30/Vps36 family
74 SPTBN4interactor21.0000Asp-B-Hydro_N (PF05279, IPR007943): Aspartyl beta-hydroxylase N-terminal region
ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
Laminin_II (PF06009, IPR010307): Laminin Domain II
Spectrin (PF00435, IPR002017): Spectrin repeat
PH_9 (PF15410): Pleckstrin homology domain
75 SRSF5interactor50.6008.564DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
76 SUGT1interactor40.16725.654CheC (PF04509, IPR007597): CheC-like family
CS (PF04969, IPR007052): CS domain
SGS (PF05002, IPR007699): SGS domain
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
TPR_16 (PF13432): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
77 SYNE4interactor208.934KASH (PF10541, IPR012315): Nuclear envelope localisation domain
78 TBC1D13interactor100RabGAP-TBC (PF00566, IPR000195, SM00164): Rab-GTPase-TBC domain
79 TBCDinteractor90.36187.413HEAT (PF02985, IPR000357): HEAT repeat
HEAT_PBS (PF03130, IPR004155, SM00567): PBS lyase HEAT-like repeat
TFCD_C (PF12612, IPR022577): Tubulin folding cofactor D C terminal
HEAT_EZ (PF13513): HEAT-like repeat
80 TOM1oncoprotein50.50018.340GAT (PF03127, IPR004152): GAT domain
VHS (PF00790, IPR002014, SM00288): VHS domain
81 TOMM34interactor30.33347.513TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
SHNi-TPR (PF10516, IPR019544): SHNi-TPR
TPR_12 (PF13424): Tetratricopeptide repeat
Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat
DUF4919 (PF16266, IPR032578): Domain of unknown function (DUF4919)
82 TSG101suppressor100.36170.625APG6 (PF04111, IPR007243): Autophagy protein Apg6
Laminin_II (PF06009, IPR010307): Laminin Domain II
UEV (PF05743, IPR008883): UEV domain
Vps23_core (PF09454, IPR017916): Vps23 core domain
83 TSNprotein found in more fusions41.0000Translin (PF01997, IPR002848): Translin family
84 TUFMinteractor100.40039.452GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain
85 TXN2interactor100Thioredoxin (PF00085, IPR013766): Thioredoxin
86 UBAC1interactor30.333116.926CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
HEAT_2 (PF13646): HEAT repeats
Rad60-SLD_2 (PF13881): Ubiquitin-2 like Rad60 SUMO-like
87 UBE2Iinteractor110.200328.209UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
88 UBE2Zinteractor21.0000UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
89 UFM1interactor100Ufm1 (PF03671, IPR005375): Ubiquitin fold modifier 1 protein
90 USP14interactor40.8330.667UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
91 VAT1interactor100ADH_N (PF08240, IPR013154): Alcohol dehydrogenase GroES-like domain
ADH_zinc_N (PF00107, IPR013149): Zinc-binding dehydrogenase
ADH_zinc_N_2 (PF13602): Zinc-binding dehydrogenase
92 VPS25interactor100.361136.638ESCRT-II (PF05871, IPR008570): ESCRT-II complex subunit
93 VPS29interactor70.47680.018Metallophos_2 (PF12850, IPR024654): Calcineurin-like phosphoesterase superfamily domain
94 VPS36interactor90.46414.050EAP30 (PF04157, IPR007286): EAP30/Vps36 family
Vps36_ESCRT-II (PF11605, IPR021648): Vacuolar protein sorting protein 36 Vps36
95 VPS37Binteractor50.7002.383Mod_r (PF07200, IPR009851): Modifier of rudimentary (Mod(r)) protein
96 WDR5interactor70.47634.721WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
97 WDR92interactor40.6674.114WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
Itfg2 (PF15907, IPR031793): Integrin-alpha FG-GAP repeat-containing protein 2
98 XPO1interactor250.153660.161CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
99 ZNF227interactor100KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_11 (PF16622, IPR007087): zinc-finger C2H2-type
100 ZNF746interactor100Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein
KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
DUF3669 (PF12417, IPR022137): Zinc finger protein
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
PRIMA1 (PF16101): Proline-rich membrane anchor 1

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