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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins NPTN, LOC643387 (from a repository: Mon Jul 31 11:00:05 2017)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)10
The number (and %) of the onco-proteins1 (10.00 %)
The number (and %) of the tumor suppressors1 (10.00 %)
Total number of binary PPIs (saturation %)12 (26.67 %)
The number (and %) of affected PPIs8 (66.67 %)
The number of possible different fusions2
PPI diameter2
PPI radiusinf
The average degree of PPI2.000
Assortativity coefficient-0.3015
The network average Clustering coefficient0.274
The number (and %) of a zero Clustering coefficients6 (60.00 %)
The number (and %) of a zero Betweenness Centrality8 (80.00 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: LOC643387,NPTN All fusions
Proteins found in more fusions LGALS3 (see 2 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 LOC643387interactor000NA
2 NPTNparental protein80.07151.000C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Ig_3 (PF13927): Immunoglobulin domain
Ig_5 (PF16681): Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain
Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
3 FBXO6interactor21.0000FBA (PF04300, IPR007397): F-box associated region
F-box-like (PF12937, IPR001810): F-box-like
4 LGALS3oncoprotein31.0000Gal-bind_lectin (PF00337, IPR001079, SM00908): Galactoside-binding lectin
5 NDUFV2interactor1002Fe-2S_thioredx (PF01257, IPR002023): Thioredoxin-like [2Fe-2S] ferredoxin
6 NIT2suppressor100CN_hydrolase (PF00795, IPR003010): Carbon-nitrogen hydrolase
7 SLC25A5interactor30.6671.000Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
8 SURF2interactor100SURF2 (PF05477, IPR008833): Surfeit locus protein 2 (SURF2)
9 UBXN1interactor200Selenoprotein_S (PF06936, IPR009703): Selenoprotein S (SelS)
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
UBX (PF00789, IPR001012, SM00166): UBX domain
10 VMA21interactor100VMA21 (PF09446, IPR019013): VMA21-like domain

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