1 |
SERBP1 | parental protein | 86 | 0.193 | 3778.507 | HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal |
2 |
DAB2 | parental protein | 79 | 0.120 | 4106.974 | PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) zf-C2H2_assoc3 (PF16637): Putative zinc-finger between two C2H2 zinc-fingers on Patz |
3 |
ACOT9 | interactor | 1 | 0 | 0 | 4HBT (PF03061, IPR006683): Thioesterase superfamily |
4 |
ACTB | oncoprotein | 32 | 0.323 | 195.591 | Actin (PF00022, IPR004000, SM00268): Actin |
5 |
ACTR2 | interactor | 24 | 0.547 | 61.818 | Actin (PF00022, IPR004000, SM00268): Actin |
6 |
AHCY | interactor | 10 | 0.528 | 11.394 | AdoHcyase (PF05221, IPR000043, SM00996): S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD (PF00670, IPR015878, SM00997): S-adenosyl-L-homocysteine hydrolase, NAD binding domain |
7 |
AHSA1 | interactor | 17 | 0.588 | 39.121 | Aha1_N (PF09229, IPR015310, SM01000): Activator of Hsp90 ATPase, N-terminal AHSA1 (PF08327, IPR013538): Activator of Hsp90 ATPase homolog 1-like protein |
8 |
ANLN | oncoprotein | 21 | 0.776 | 13.408 | Anillin (PF08174, IPR012966): Cell division protein anillin PH (PF00169, IPR001849, SM00233): PH domain Anillin_N (PF16018, IPR031970): Anillin N-terminus |
9 |
AP2A1 | interactor | 30 | 0.561 | 120.147 | Adaptin_N (PF01602, IPR002553): Adaptin N terminal region Alpha_adaptin_C (PF02296, IPR003164): Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 (PF02883, IPR008152, SM00809): Adaptin C-terminal domain HEAT_2 (PF13646): HEAT repeats |
10 |
AP2A2 | interactor | 19 | 0.596 | 23.049 | Adaptin_N (PF01602, IPR002553): Adaptin N terminal region Alpha_adaptin_C (PF02296, IPR003164): Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 (PF02883, IPR008152, SM00809): Adaptin C-terminal domain HEAT_2 (PF13646): HEAT repeats |
11 |
AP2B1 | interactor | 27 | 0.481 | 135.693 | Adaptin_N (PF01602, IPR002553): Adaptin N terminal region Alpha_adaptinC2 (PF02883, IPR008152, SM00809): Adaptin C-terminal domain B2-adapt-app_C (PF09066, IPR015151, SM01020): Beta2-adaptin appendage, C-terminal sub-domain |
12 |
AP2M1 | protein found in more fusions | 36 | 0.413 | 254.178 | Adap_comp_sub (PF00928, IPR008968): Adaptor complexes medium subunit family Clat_adaptor_s (PF01217, IPR022775): Clathrin adaptor complex small chain |
13 |
APLP1 | interactor | 3 | 0.333 | 3.225 | APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus Ints3 (PF10189, IPR019333): Integrator complex subunit 3 APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein |
14 |
APLP2 | interactor | 3 | 0 | 5.530 | APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding ELM2 (PF01448, IPR000949): ELM2 domain Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain Usp (PF00582, IPR006016): Universal stress protein family YL1 (PF05764, IPR008895): YL1 nuclear protein APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
15 |
APP | protein found in more fusions | 36 | 0.235 | 669.507 | APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP) BUD22 (PF09073, IPR015158): BUD22 IncA (PF04156, IPR007285): IncA protein Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein |
16 |
ARRB2 | interactor | 33 | 0.271 | 259.550 | Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain |
17 |
ATP5A1 | protein found in more fusions | 27 | 0.437 | 82.573 | ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C (PF00306, IPR000793): ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain |
18 |
ATXN1L | interactor | 5 | 0.333 | 2.300 | AXH (PF08517, IPR013723, SM00536): Ataxin-1 and HBP1 module (AXH) |
19 |
AURKA | oncoprotein | 21 | 0.389 | 77.963 | Pkinase (PF00069, IPR000719): Protein kinase domain MTBP_C (PF14920, IPR029418): MDM2-binding |
20 |
AXIN1 | suppressor | 13 | 0.379 | 43.119 | Axin_b-cat_bind (PF08833, IPR014936): Axin beta-catenin binding domain RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain DIX (PF00778, IPR001158, SM00021): DIX domain AXIN1_TNKS_BD (PF16646, IPR032101): Axin-1 tankyrase binding domain |
21 |
BASP1 | suppressor | 18 | 0.497 | 108.548 | BASP1 (PF05466, IPR008408): Brain acid soluble protein 1 (BASP1 protein) |
22 |
C14orf166 | interactor | 13 | 0.551 | 18.671 | RLL (PF10036, IPR019265): Putative carnitine deficiency-associated protein |
23 |
CAND1 | interactor | 45 | 0.379 | 311.340 | Adaptin_N (PF01602, IPR002553): Adaptin N terminal region DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981) HEAT (PF02985, IPR000357): HEAT repeat TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20) RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II |
24 |
CAPZA2 | interactor | 25 | 0.647 | 41.340 | F-actin_cap_A (PF01267, IPR002189): F-actin capping protein alpha subunit |
25 |
CCNT1 | oncoprotein | 5 | 0 | 7.474 | Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region RP-C_C (PF11800, IPR021760): Replication protein C C-terminal region CENP-Q (PF13094, IPR025212): CENP-Q, a CENPA-CAD centromere complex subunit MDFI (PF15316, IPR026134): MyoD family inhibitor |
26 |
CD81 | interactor | 19 | 0.471 | 21.735 | Tetraspannin (PF00335, IPR018499): Tetraspanin family |
27 |
CDC16 | interactor | 6 | 0.400 | 12.612 | Dynein_light (PF01221, IPR001372): Dynein light chain type 1 TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 (PF13424): Tetratricopeptide repeat TPR_17 (PF13431): Tetratricopeptide repeat TPR_16 (PF13432): Tetratricopeptide repeat SRP_TPR_like (PF17004, IPR031545): Putative TPR-like repeat |
28 |
CDK1 | oncoprotein | 11 | 0.289 | 41.449 | Pkinase (PF00069, IPR000719): Protein kinase domain |
29 |
CFTR | suppressor | 8 | 0.190 | 16.719 | ABC_membrane (PF00664, IPR001140): ABC transporter transmembrane region ABC_tran (PF00005, IPR003439): ABC transporter Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain Rotamase_2 (PF13145, IPR000297): PPIC-type PPIASE domain CFTR_R (PF14396, IPR025837): Cystic fibrosis TM conductance regulator (CFTR), regulator domain |
30 |
CHD3 | oncoprotein | 9 | 0.500 | 11.727 | CHDCT2 (PF08074, IPR012957): CHDCT2 (NUC038) domain CHDNT (PF08073, IPR012958): CHDNT (NUC034) domain Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain DUF1086 (PF06461, IPR009462, SM01146): Domain of Unknown Function (DUF1086) DUF1087 (PF06465, IPR009463, SM01147): Domain of Unknown Function (DUF1087) DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid) PHD (PF00628, IPR019787, SM00249): PHD-finger Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein SMN (PF06003, IPR010304): Survival motor neuron protein (SMN) SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain DUF2956 (PF11169, IPR021339): Protein of unknown function (DUF2956) FAM176 (PF14851): FAM176 family |
31 |
CLTB | interactor | 28 | 0.640 | 48.666 | Clathrin_lg_ch (PF01086, IPR000996): Clathrin light chain |
32 |
CLTC | oncoprotein | 45 | 0.348 | 483.621 | Clathrin-link (PF09268, IPR015348): Clathrin, heavy-chain linker Clathrin_propel (PF01394, IPR022365): Clathrin propeller repeat Clathrin (PF00637, IPR000547, SM00299): Region in Clathrin and VPS Clathrin_H_link (PF13838): Clathrin-H-link |
33 |
CPSF6 | interactor | 14 | 0.352 | 44.767 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
34 |
CPSF7 | interactor | 13 | 0.372 | 28.317 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term PRIMA1 (PF16101): Proline-rich membrane anchor 1 |
35 |
CSK | interactor | 6 | 0.400 | 3.243 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
36 |
CSNK2A1 | oncoprotein | 35 | 0.257 | 301.307 | Pkinase (PF00069, IPR000719): Protein kinase domain |
37 |
CTNNB1 | oncoprotein | 30 | 0.232 | 311.224 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361) HEAT_EZ (PF13513): HEAT-like repeat |
38 |
CUL1 | suppressor | 43 | 0.360 | 244.399 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
39 |
CUL3 | protein found in more fusions | 60 | 0.252 | 800.695 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal |
40 |
DAB2IP | suppressor | 6 | 0.267 | 10.497 | C2 (PF00168, IPR000008, SM00239): C2 domain PH_2 (PF08458, IPR013666): Plant pleckstrin homology-like region RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase DUF3498 (PF12004, IPR021887): Domain of unknown function (DUF3498) |
41 |
DAXX | oncoprotein | 10 | 0.361 | 34.636 | Daxx (PF03344, IPR005012): Daxx N-terminal Rassf1C-interacting domain Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM) Nop14 (PF04147, IPR007276): Nop14-like family RF-1 (PF00472, IPR000352): RF-1 domain Vpu (PF00558, IPR008187): Vpu protein DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391) |
42 |
DBN1 | oncoprotein | 36 | 0.470 | 205.747 | Pinin_SDK_memA (PF04696, IPR006786): pinin/SDK/memA/ protein conserved region Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein CAF-1_p150 (PF11600): Chromatin assembly factor 1 complex p150 subunit, N-terminal MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c |
43 |
DVL1 | interactor | 11 | 0.556 | 10.218 | DEP (PF00610, IPR000591, SM00049): Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Dishevelled (PF02377, IPR003351): Dishevelled specific domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) DIX (PF00778, IPR001158, SM00021): DIX domain Dsh_C (PF12316, IPR024580): Segment polarity protein dishevelled (Dsh) C terminal |
44 |
DVL2 | interactor | 16 | 0.400 | 48.396 | DEP (PF00610, IPR000591, SM00049): Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Dishevelled (PF02377, IPR003351): Dishevelled specific domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) DIX (PF00778, IPR001158, SM00021): DIX domain Dsh_C (PF12316, IPR024580): Segment polarity protein dishevelled (Dsh) C terminal |
45 |
DVL3 | protein found in more fusions | 11 | 0.600 | 14.142 | DEP (PF00610, IPR000591, SM00049): Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Dishevelled (PF02377, IPR003351): Dishevelled specific domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) DIX (PF00778, IPR001158, SM00021): DIX domain Dsh_C (PF12316, IPR024580): Segment polarity protein dishevelled (Dsh) C terminal |
46 |
DYNC1H1 | interactor | 19 | 0.363 | 110.041 | AAA_5 (PF07728, IPR011704): AAA domain (dynein-related subfamily) DHC_N1 (PF08385, IPR013594): Dynein heavy chain, N-terminal region 1 DHC_N2 (PF08393, IPR013602): Dynein heavy chain, N-terminal region 2 DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948) Dynein_heavy (PF03028, IPR004273): Dynein heavy chain and region D6 of dynein motor Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family AAA_6 (PF12774): Hydrolytic ATP binding site of dynein motor region D1 AAA_7 (PF12775): P-loop containing dynein motor region D3 MT (PF12777, IPR024743): Microtubule-binding stalk of dynein motor AAA_8 (PF12780, IPR024317): P-loop containing dynein motor region D4 AAA_9 (PF12781): ATP-binding dynein motor region D5 |
47 |
DYNC1I2 | interactor | 8 | 0.571 | 16.488 | Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1 WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052) Dynein_IC2 (PF11540, IPR025956): Cytoplasmic dynein 1 intermediate chain 2 ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain DUF4329 (PF14220, IPR025479): Domain of unknown function (DUF4329) |
48 |
DYNC1LI1 | interactor | 7 | 0.762 | 12.976 | DLIC (PF05783, IPR022780): Dynein light intermediate chain (DLIC) |
49 |
DYNLT3 | interactor | 7 | 0.600 | 3.473 | Tctex-1 (PF03645, IPR005334): Tctex-1 family |
50 |
EIF2A | interactor | 10 | 0.622 | 7.601 | Bap31 (PF05529, IPR008417): B-cell receptor-associated protein 31-like eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A |
51 |
ELAVL1 | oncoprotein | 40 | 0.211 | 599.966 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
52 |
ESR1 | suppressor | 42 | 0.289 | 410.013 | Oest_recep (PF02159, IPR001292): Oestrogen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal |
53 |
FAU | interactor | 21 | 0.643 | 20.588 | Ribosomal_S30 (PF04758, IPR006846): Ribosomal protein S30 ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
54 |
FBXO25 | suppressor | 15 | 0.333 | 42.081 | Elongin_A (PF06881, IPR010684): RNA polymerase II transcription factor SIII (Elongin) subunit A |
55 |
FBXW7 | suppressor | 11 | 0.222 | 31.931 | Mem_trans (PF03547, IPR004776): Membrane transport protein WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 F-box-like (PF12937, IPR001810): F-box-like |
56 |
FCHO2 | protein found in more fusions | 13 | 0.795 | 9.612 | DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) FCH (PF00611, IPR001060, SM00055): Fes/CIP4, and EFC/F-BAR homology domain PIN_2 (PF10130, IPR002716): PIN domain muHD (PF10291, IPR018808): Muniscin C-terminal mu homology domain |
57 |
FGR | oncoprotein | 2 | 1.000 | 0 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
58 |
FLNA | suppressor | 42 | 0.370 | 420.379 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain Filamin (PF00630, IPR017868): Filamin/ABP280 repeat |
59 |
FN1 | oncoprotein | 57 | 0.259 | 697.052 | fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) |
60 |
FUS | suppressor | 36 | 0.322 | 298.134 | Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others Limkain-b1 (PF11608, IPR024582): Limkain b1 FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 Keratin_2_head (PF16208, IPR032444): Keratin type II head |
61 |
FXYD3 | interactor | 1 | 0 | 0 | ATP1G1_PLM_MAT8 (PF02038, IPR000272): ATP1G1/PLM/MAT8 family |
62 |
FYTTD1 | interactor | 3 | 0 | 1.687 | FYTT (PF07078, IPR009782): Forty-two-three protein |
63 |
GAK | oncoprotein | 18 | 0.556 | 46.093 | DnaJ (PF00226, IPR001623, SM00271): DnaJ domain DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain Pkinase (PF00069, IPR000719): Protein kinase domain PTEN_C2 (PF10409, IPR014020): C2 domain of PTEN tumour-suppressor protein |
64 |
GARS | interactor | 3 | 1.000 | 0 | HGTP_anticodon (PF03129, IPR004154): Anticodon binding domain tRNA-synt_2b (PF00587, IPR002314): tRNA synthetase class II core domain (G, H, P, S and T) WHEP-TRS (PF00458, IPR000738, SM00991): WHEP-TRS domain |
65 |
GRB2 | oncoprotein | 34 | 0.333 | 383.629 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain DUF5093 (PF17011, IPR031533): Domain of unknown function (DUF5093) |
66 |
GTSE1 | interactor | 21 | 0.667 | 21.806 | GTSE1_N (PF15259, IPR032768): G-2 and S-phase expressed 1 |
67 |
HIST1H3E | interactor | 15 | 0.390 | 30.469 | Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 |
68 |
HNRNPL | protein found in more fusions | 20 | 0.421 | 87.975 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Dscam_C (PF12355, IPR021012): Down syndrome cell adhesion molecule C terminal RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
69 |
HNRNPR | interactor | 21 | 0.533 | 51.194 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 (PF11608, IPR024582): Limkain b1 |
70 |
HNRNPU | interactor | 50 | 0.369 | 420.368 | CDC45 (PF02724, IPR003874): CDC45-like protein Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein SAP (PF02037, IPR003034, SM00513): SAP domain SPRY (PF00622, IPR003877, SM00449): SPRY domain AAA_33 (PF13671): AAA domain WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
71 |
HSPA1B | interactor | 13 | 0.346 | 26.697 | HSP70 (PF00012, IPR013126): Hsp70 protein |
72 |
HSPH1 | oncoprotein | 12 | 0.242 | 63.813 | HSP70 (PF00012, IPR013126): Hsp70 protein SICA_alpha (PF12887, IPR024290): SICA extracellular alpha domain |
73 |
HUWE1 | oncoprotein | 31 | 0.418 | 142.989 | BUD22 (PF09073, IPR015158): BUD22 DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908) DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913) FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM) Mucin (PF01456, IPR000458): Mucin-like glycoprotein Nop14 (PF04147, IPR007276): Nop14-like family PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32 RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain WWE (PF02825, IPR004170, SM00678): WWE domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54 U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414) |
74 |
INPP5D | interactor | 4 | 0.667 | 1.293 | Exo_endo_phos (PF03372, IPR005135): Endonuclease/Exonuclease/phosphatase family SH2 (PF00017, IPR000980, SM00252): SH2 domain |
75 |
IQGAP1 | interactor | 33 | 0.420 | 190.020 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain DUF87 (PF01935, IPR002789): Domain of unknown function DUF87 IDEAL (PF08858, IPR014957, SM00914): IDEAL domain IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase RasGAP_C (PF03836, IPR000593): RasGAP C-terminus WW (PF00397, IPR001202, SM00456): WW domain |
76 |
ISG15 | suppressor | 17 | 0.301 | 34.509 | ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
77 |
ITFG1 | interactor | 1 | 0 | 0 | FG-GAP (PF01839, IPR013517): FG-GAP repeat K1 (PF02960, IPR004121): K1 glycoprotein VCBS (PF13517): Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella |
78 |
ITSN1 | protein found in more fusions | 7 | 0.800 | 0.806 | C2 (PF00168, IPR000008, SM00239): C2 domain VIT1 (PF01988, IPR008217): VIT family DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) FmdE (PF02663, IPR003814): FmdE, Molybdenum formylmethanofuran dehydrogenase operon GSH_synthase (PF03199, IPR004887): Eukaryotic glutathione synthase RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) SH3_9 (PF14604, IPR001452): Variant SH3 domain DUF4748 (PF15932, IPR031833): Domain of unknown function (DUF4748) INTAP (PF16617): Intersectin and clathrin adaptor AP2 binding region PH_13 (PF16652, IPR001849): Pleckstrin homology domain |
79 |
KAT2B | protein found in more fusions | 12 | 0.309 | 40.521 | Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family PCAF_N (PF06466, IPR009464): PCAF (P300/CBP-associated factor) N-terminal domain Bromodomain (PF00439, IPR001487, SM00297): Bromodomain |
80 |
LDLR | interactor | 2 | 0 | 2.469 | EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain Ldl_recept_a (PF00057, IPR002172, SM00192): Low-density lipoprotein receptor domain class A Ldl_recept_b (PF00058, IPR000033, SM00135): Low-density lipoprotein receptor repeat class B hEGF (PF12661, IPR013032): Human growth factor-like EGF FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site |
81 |
LIMA1 | suppressor | 31 | 0.544 | 103.380 | LIM (PF00412, IPR001781, SM00132): LIM domain ROKNT (PF08067, IPR012987): ROKNT (NUC014) domain |
82 |
LRP1 | interactor | 4 | 0.667 | 1.233 | EGF (PF00008, IPR000742, SM00181): EGF-like domain EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain SGL (PF08450, IPR013658): SMP-30/Gluconolaconase/LRE-like region TadE (PF07811, IPR012495): TadE-like protein Ldl_recept_a (PF00057, IPR002172, SM00192): Low-density lipoprotein receptor domain class A Ldl_recept_b (PF00058, IPR000033, SM00135): Low-density lipoprotein receptor repeat class B hEGF (PF12661, IPR013032): Human growth factor-like EGF cEGF (PF12662, IPR026823): Complement Clr-like EGF-like EGF_3 (PF12947, IPR024731): EGF domain FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site DUF5050 (PF16472, IPR032485): Domain of unknown function (DUF5050) |
83 |
LRP2 | oncoprotein | 2 | 1.000 | 0 | Arylesterase (PF01731, IPR002640): Arylesterase EGF (PF00008, IPR000742, SM00181): EGF-like domain EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain Form-deh_trans (PF09163, IPR015246): Formate dehydrogenase N, transmembrane SGL (PF08450, IPR013658): SMP-30/Gluconolaconase/LRE-like region Ldl_recept_a (PF00057, IPR002172, SM00192): Low-density lipoprotein receptor domain class A Ldl_recept_b (PF00058, IPR000033, SM00135): Low-density lipoprotein receptor repeat class B cEGF (PF12662, IPR026823): Complement Clr-like EGF-like FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site |
84 |
MALT1 | oncoprotein | 3 | 1.000 | 0 | Peptidase_C14 (PF00656, IPR011600): Caspase domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_2 (PF13895, IPR007110): Immunoglobulin domain Ig_3 (PF13927): Immunoglobulin domain |
85 |
MAP1LC3A | interactor | 7 | 0.238 | 12.760 | Atg8 (PF02991, IPR004241): Autophagy protein Atg8 ubiquitin like |
86 |
MAP4 | oncoprotein | 13 | 0.256 | 132.990 | SdiA-regulated (PF06977, IPR009722): SdiA-regulated Tubulin-binding (PF00418, IPR001084): Tau and MAP protein, tubulin-binding repeat DUF3275 (PF11679, IPR021693): Protein of unknown function (DUF3275) |
87 |
MAPRE1 | oncoprotein | 20 | 0.310 | 133.660 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain EB1 (PF03271, IPR004953): EB1-like C-terminal motif SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3 |
88 |
MCM2 | oncoprotein | 56 | 0.279 | 653.060 | AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA) MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2 MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain |
89 |
MDC1 | suppressor | 12 | 0.333 | 83.458 | FHA (PF00498, IPR000253, SM00240): FHA domain DUF3274 (PF11678, IPR021692): Protein of unknown function (DUF3274) Yop-YscD_cpl (PF16697, IPR032030): Inner membrane component of T3SS, cytoplasmic domain RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain |
90 |
MYH9 | suppressor | 40 | 0.432 | 238.184 | IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain Myosin_tail_1 (PF01576, IPR002928): Myosin tail Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) |
91 |
MYO18A | interactor | 22 | 0.771 | 14.747 | Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1 IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_tail_1 (PF01576, IPR002928): Myosin tail PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2 |
92 |
MYO19 | interactor | 22 | 0.797 | 11.576 | IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) |
93 |
MYO6 | protein found in more fusions | 25 | 0.536 | 92.498 | BUD22 (PF09073, IPR015158): BUD22 IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain Rad9 (PF04139, IPR007268): Rad9 Sec62 (PF03839, IPR004728): Translocation protein Sec62 XhlA (PF10779, IPR019715): Haemolysin XhlA Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain) DUF4887 (PF16228, IPR032615): Domain of unknown function (DUF4887) Myosin-VI_CBD (PF16521, IPR032412): Myosin VI cargo binding domain |
94 |
NEDD8 | interactor | 21 | 0.368 | 70.106 | ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
95 |
NF2 | suppressor | 12 | 0.127 | 32.277 | ERM (PF00769, IPR011259): Ezrin/radixin/moesin family FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain FERM_M (PF00373, IPR019748): FERM central domain FERM_N (PF09379, IPR018979): FERM N-terminal domain |
96 |
NPM1 | suppressor | 51 | 0.424 | 278.241 | Nucleoplasmin (PF03066): Nucleoplasmin/nucleophosmin domain SDA1 (PF05285, IPR007949): SDA1 NPM1-C (PF16276, IPR032569): Nucleophosmin C-terminal domain |
97 |
NTRK1 | oncoprotein | 77 | 0.169 | 2147.435 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain |
98 |
NUP155 | interactor | 6 | 0.267 | 6.073 | Nucleoporin_C (PF03177, IPR007187): Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N (PF08801, IPR014908): Nup133 N terminal like |
99 |
OTUB1 | interactor | 17 | 0.353 | 81.617 | Peptidase_C65 (PF10275, IPR019400): Peptidase C65 Otubain |
100 |
PA2G4 | interactor | 15 | 0.448 | 21.953 | Peptidase_M24 (PF00557, IPR001714): Metallopeptidase family M24 Ribosomal_S25 (PF03297, IPR004977): S25 ribosomal protein TraC (PF07820, IPR012930): TraC-like protein |
101 |
PABPC1 | oncoprotein | 33 | 0.383 | 222.881 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain YflT (PF11181, IPR025889): Heat induced stress protein YflT |
102 |
PAN2 | interactor | 34 | 0.383 | 199.899 | RNase_T (PF00929, IPR013520): Exonuclease UCH_1 (PF13423, IPR001394): Ubiquitin carboxyl-terminal hydrolase WD40_like (PF17005, IPR031544): WD40-like domain |
103 |
PARK2 | suppressor | 26 | 0.397 | 67.869 | IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
104 |
PCAP | oncoprotein | 1 | 0 | 0 | NA |
105 |
PIAS1 | suppressor | 6 | 0.800 | 0.828 | Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein zf-MIZ (PF02891, IPR004181): MIZ/SP-RING zinc finger PINIT (PF14324, IPR023321): PINIT domain UPF0544 (PF15749, IPR032739): Uncharacterised protein family UPF0544 |
106 |
PIAS3 | oncoprotein | 5 | 0.500 | 33.933 | SAP (PF02037, IPR003034, SM00513): SAP domain zf-MIZ (PF02891, IPR004181): MIZ/SP-RING zinc finger PINIT (PF14324, IPR023321): PINIT domain |
107 |
PIAS4 | interactor | 9 | 0.444 | 21.647 | CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain SAP (PF02037, IPR003034, SM00513): SAP domain zf-MIZ (PF02891, IPR004181): MIZ/SP-RING zinc finger PINIT (PF14324, IPR023321): PINIT domain |
108 |
PICALM | oncoprotein | 25 | 0.560 | 111.297 | ANTH (PF07651, IPR011417): ANTH domain |
109 |
PIN1 | suppressor | 17 | 0.257 | 117.325 | Rotamase (PF00639, IPR000297): PPIC-type PPIASE domain WW (PF00397, IPR001202, SM00456): WW domain |
110 |
PPP1CB | interactor | 26 | 0.502 | 109.103 | Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain |
111 |
PRDX1 | oncoprotein | 16 | 0.305 | 44.767 | AhpC-TSA (PF00578, IPR000866): AhpC/TSA family 1-cysPrx_C (PF10417, IPR019479): C-terminal domain of 1-Cys peroxiredoxin |
112 |
PRKCB | suppressor | 6 | 0.400 | 4.493 | C2 (PF00168, IPR000008, SM00239): C2 domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) |
113 |
PRKCD | suppressor | 9 | 0.214 | 43.849 | Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) |
114 |
PRKCG | interactor | 4 | 0.667 | 0.558 | C2 (PF00168, IPR000008, SM00239): C2 domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) |
115 |
PRMT8 | interactor | 5 | 0.667 | 0.489 | PrmA (PF06325, IPR010456): Ribosomal protein L11 methyltransferase (PrmA) |
116 |
PYCR1 | interactor | 6 | 0.333 | 25.397 | ApbA (PF02558, IPR013332): Ketopantoate reductase PanE/ApbA F420_oxidored (PF03807, IPR028939): NADP oxidoreductase coenzyme F420-dependent P5CR_dimer (PF14748, IPR029036): Pyrroline-5-carboxylate reductase dimerisation |
117 |
RPL10 | suppressor | 33 | 0.568 | 96.886 | Ribosomal_L16 (PF00252, IPR016180): Ribosomal protein L16p/L10e |
118 |
RPL37A | protein found in more fusions | 26 | 0.680 | 48.205 | Ribosomal_L37ae (PF01780, IPR002674): Ribosomal L37ae protein family |
119 |
RPL4 | interactor | 39 | 0.494 | 147.033 | Ribosomal_L4 (PF00573, IPR002136): Ribosomal protein L4/L1 family Ribos_L4_asso_C (PF14374, IPR025755): 60S ribosomal protein L4 C-terminal domain |
120 |
RPS10 | interactor | 36 | 0.525 | 135.378 | S10_plectin (PF03501, IPR005326): Plectin/S10 domain |
121 |
RPS14 | protein found in more fusions | 38 | 0.545 | 118.045 | Ribosomal_S11 (PF00411, IPR001971): Ribosomal protein S11 |
122 |
RPS19 | protein found in more fusions | 38 | 0.508 | 134.558 | Ribosomal_S19e (PF01090, IPR001266): Ribosomal protein S19e |
123 |
RPS20 | interactor | 32 | 0.587 | 71.753 | Ribosomal_S10 (PF00338, IPR027486): Ribosomal protein S10p/S20e |
124 |
RPS23 | protein found in more fusions | 34 | 0.585 | 65.331 | Ribosom_S12_S23 (PF00164, IPR006032): Ribosomal protein S12/S23 |
125 |
RPS24 | protein found in more fusions | 31 | 0.660 | 36.158 | Fascin (PF06268, IPR022768): Fascin domain Ribosomal_S24e (PF01282, IPR001976): Ribosomal protein S24e DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457) |
126 |
RPS25 | interactor | 36 | 0.583 | 81.941 | Ribosomal_S25 (PF03297, IPR004977): S25 ribosomal protein |
127 |
RPS26 | interactor | 26 | 0.662 | 39.779 | Ribosomal_S26e (PF01283, IPR000892): Ribosomal protein S26e |
128 |
RPS29 | interactor | 19 | 0.784 | 17.467 | Ribosomal_S14 (PF00253, IPR001209): Ribosomal protein S14p/S29e |
129 |
RPS3 | interactor | 41 | 0.500 | 178.615 | KH_2 (PF07650, IPR004044): KH domain Ribosomal_S3_C (PF00189, IPR001351): Ribosomal protein S3, C-terminal domain |
130 |
RPS6 | interactor | 38 | 0.533 | 133.815 | Ribosomal_S6e (PF01092, IPR001377): Ribosomal protein S6e DUF4574 (PF15141, IPR027896): Domain of unknown function (DUF4574) |
131 |
RPS6KB2 | interactor | 17 | 0.346 | 47.109 | Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
132 |
SEC23B | protein found in more fusions | 12 | 0.418 | 18.794 | Gelsolin (PF00626, IPR007123): Gelsolin repeat Sec23_BS (PF08033, IPR012990): Sec23/Sec24 beta-sandwich domain Sec23_helical (PF04815, IPR006900): Sec23/Sec24 helical domain Sec23_trunk (PF04811, IPR006896): Sec23/Sec24 trunk domain zf-Sec23_Sec24 (PF04810, IPR006895): Sec23/Sec24 zinc finger |
133 |
SEC24B | interactor | 8 | 0.607 | 5.568 | Gelsolin (PF00626, IPR007123): Gelsolin repeat Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein Sec23_BS (PF08033, IPR012990): Sec23/Sec24 beta-sandwich domain Sec23_helical (PF04815, IPR006900): Sec23/Sec24 helical domain Sec23_trunk (PF04811, IPR006896): Sec23/Sec24 trunk domain zf-Sec23_Sec24 (PF04810, IPR006895): Sec23/Sec24 zinc finger |
134 |
SF3B2 | interactor | 11 | 0.309 | 17.608 | DUF382 (PF04037, IPR007180): Domain of unknown function (DUF382) PAPA-1 (PF04795, IPR006880): PAPA-1-like conserved region PSP (PF04046, IPR006568, SM00581): PSP SAP (PF02037, IPR003034, SM00513): SAP domain Usp (PF00582, IPR006016): Universal stress protein family Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19 Vma12 (PF11712, IPR021013): Endoplasmic reticulum-based factor for assembly of V-ATPase FAM176 (PF14851): FAM176 family WRNPLPNID (PF15017): Putative WW-binding domain and destruction box |
135 |
SFN | suppressor | 22 | 0.500 | 100.157 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |
136 |
SFPQ | oncoprotein | 24 | 0.304 | 91.872 | GRP (PF07172, IPR010800): Glycine rich protein family Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein NOPS (PF08075, IPR012975): NOPS (NUC059) domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit PAT1 (PF09770, IPR019167): Topoisomerase II-associated protein PAT1 CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance |
137 |
SH3KBP1 | protein found in more fusions | 20 | 0.199 | 210.529 | Tmemb_cc2 (PF10267, IPR019394): Predicted transmembrane and coiled-coil 2 protein SH3_9 (PF14604, IPR001452): Variant SH3 domain |
138 |
SIRT7 | interactor | 38 | 0.302 | 282.924 | DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563) SIR2 (PF02146, IPR003000): Sir2 family |
139 |
SLC25A41 | interactor | 6 | 0.667 | 3.262 | Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein |
140 |
SMAD2 | suppressor | 20 | 0.269 | 166.935 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
141 |
SMAD3 | oncoprotein | 25 | 0.228 | 271.789 | MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain |
142 |
SMURF2 | protein found in more fusions | 8 | 0.524 | 20.728 | C2 (PF00168, IPR000008, SM00239): C2 domain WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) |
143 |
SRC | oncoprotein | 18 | 0.265 | 214.694 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
144 |
SYNPO | interactor | 22 | 0.710 | 21.249 | Calsarcin (PF05556, IPR008438): Calcineurin-binding protein (Calsarcin) |
145 |
TARDBP | interactor | 32 | 0.527 | 77.781 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
146 |
TDG | interactor | 3 | 1.000 | 0 | Pox_Ag35 (PF03286, IPR004966): Pox virus Ag35 surface protein UDG (PF03167, IPR005122, SM00986): Uracil DNA glycosylase superfamily |
147 |
TDRD3 | interactor | 4 | 0.667 | 0.251 | RMI1_N (PF08585, IPR013894, SM01161): RecQ mediated genome instability protein TUDOR (PF00567, IPR002999, SM00333): Tudor domain UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain DUF3472 (PF11958, IPR021862): Domain of unknown function (DUF3472) |
148 |
TERT | oncoprotein | 5 | 0.600 | 11.361 | RVT_1 (PF00078, IPR000477): Reverse transcriptase (RNA-dependent DNA polymerase) Telomerase_RBD (PF12009, IPR021891, SM00975): Telomerase ribonucleoprotein complex - RNA binding domain |
149 |
TFAP2A | suppressor | 9 | 0.361 | 15.933 | TF_AP-2 (PF03299, IPR013854): Transcription factor AP-2 CYYR1 (PF10873, IPR022640): Cysteine and tyrosine-rich protein 1 Peptidase_Prp (PF04327): Cysteine protease Prp |
150 |
TGFBR1 | oncoprotein | 9 | 0.444 | 20.272 | Activin_recp (PF01064, IPR000472): Activin types I and II receptor domain Pkinase (PF00069, IPR000719): Protein kinase domain TGF_beta_GS (PF08515, IPR003605, SM00467): Transforming growth factor beta type I GS-motif |
151 |
TGFBR2 | suppressor | 10 | 0.267 | 64.230 | ecTbetaR2 (PF08917, IPR015013): Transforming growth factor beta receptor 2 ectodomain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase |
152 |
TOPORS | suppressor | 4 | 0.667 | 0.772 | Rad50_zn_hook (PF04423, IPR007517): Rad50 zinc hook motif Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19 PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) |
153 |
TP53 | suppressor | 59 | 0.191 | 1190.707 | DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif |
154 |
TRIM29 | protein found in more fusions | 8 | 0.571 | 3.775 | MIS13 (PF08202, IPR013218): Mis12-Mtw1 protein family TP2 (PF01254, IPR000678): Nuclear transition protein 2 zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger |
155 |
TRIO | oncoprotein | 4 | 0.833 | 0.494 | T3SS_needle_E (PF08988, IPR012671): Type III secretion system, cytoplasmic E component of needle GRP (PF07172, IPR010800): Glycine rich protein family I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pap_E4 (PF02711, IPR003861): E4 protein PH (PF00169, IPR001849, SM00233): PH domain Pkinase (PF00069, IPR000719): Protein kinase domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain Spectrin (PF00435, IPR002017): Spectrin repeat CRAL_TRIO (PF00650, IPR001251, SM00516): CRAL/TRIO domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain Myb_DNA-bind_4 (PF13837): Myb/SANT-like DNA-binding domain PH_10 (PF15411): Pleckstrin homology domain SH3-RhoG_link (PF16609): SH3-RhoGEF linking unstructured region |
156 |
TSR1 | interactor | 20 | 0.837 | 6.423 | AARP2CN (PF08142, IPR012948, SM00785): AARP2CN (NUC121) domain RIBIOP_C (PF04950, IPR007034): 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal NUSAP (PF16006, IPR026756): Nucleolar and spindle-associated protein |
157 |
U2AF2 | protein found in more fusions | 33 | 0.347 | 156.140 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transformer (PF06495, IPR010519): Fruit fly transformer protein |
158 |
UBA2 | interactor | 3 | 0.667 | 0.321 | ThiF (PF00899, IPR000594): ThiF family UAE_UbL (PF14732, IPR028077): Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA2_C (PF16195, IPR032426): SUMO-activating enzyme subunit 2 C-terminus |
159 |
UPF2 | interactor | 8 | 0.667 | 1.976 | DDHD (PF02862, IPR004177, SM01127): DDHD domain DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510) MIF4G (PF02854, IPR003890, SM00543): MIF4G domain Upf2 (PF04050, IPR007193): Up-frameshift suppressor 2 MIP-T3 (PF10243): Microtubule-binding protein MIP-T3 SUFU_C (PF12470, IPR024314): Suppressor of Fused Gli/Ci N terminal binding domain |
160 |
VAV2 | oncoprotein | 6 | 0.467 | 6.024 | PH (PF00169, IPR001849, SM00233): PH domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_2 (PF07653, IPR011511): Variant SH3 domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) CAMSAP_CH (PF11971, IPR022613): CAMSAP CH domain CotJB (PF12652, IPR024207): CotJB protein |
161 |
VIM | suppressor | 24 | 0.221 | 236.093 | Filament (PF00038, IPR001664): Intermediate filament protein Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region |
162 |
WDR5 | interactor | 11 | 0.418 | 14.804 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat |
163 |
XPO1 | interactor | 45 | 0.217 | 797.518 | CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain Xpo1 (PF08389, IPR013598): Exportin 1-like protein Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region |
164 |
YLPM1 | interactor | 5 | 0.500 | 1.551 | DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator Com_YlbF (PF06133, IPR010368): Control of competence regulator ComK, YlbF/YmcA TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit AAA_33 (PF13671): AAA domain PRIMA1 (PF16101): Proline-rich membrane anchor 1 |