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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins RALGPS2, MDS2 (from a repository: Fri Jul 12 06:00:54 2019)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)6
The number (and %) of the onco-proteins3 (50.00 %)
The number (and %) of the tumor suppressors1 (16.67 %)
Total number of binary PPIs (saturation %)12 (80.00 %)
The number (and %) of affected PPIs4 (33.33 %)
The number of possible different fusions4
PPI diameter2
PPI radiusinf
The average degree of PPI3.000
Assortativity coefficient-0.4781
The network average Clustering coefficient0.750
The number (and %) of a zero Clustering coefficients1 (16.67 %)
The number (and %) of a zero Betweenness Centrality3 (50.00 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: RALGPS2,MDS2 All fusions
Proteins found in more fusions SFN (see 1 fusions); YWHAG (see 1 fusions); YWHAZ (see 5 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 RALGPS2parental protein40.8330.667PH (PF00169, IPR001849, SM00233): PH domain
RasGEF (PF00617, IPR001895, SM00147): RasGEF domain
2 MDS2oncoprotein000NA
3 SFNsuppressor41.000014-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
4 YWHABinteractor31.000014-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
Virulence_fact (PF13769, IPR025989): Virulence factor
5 YWHAGprotein found in more fusions50.8330.66714-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
6 YWHAZprotein found in more fusions50.8330.66714-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein

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