Find Fusion Network

Fusion ID:
Protein names:

Level of PPIs:
or Upload text file:
Update repository
Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins CTSK, ZNF549 (from a repository: Mon Nov 5 11:51:56 2018)

Cytoscape Web will replace the contents your graph
PPI Properties:

Click on nodes
or edges

Layout Tree
Force Directed
Export graph
PDF file
SVG file
SIF file
XML file
GraphML file

Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)9
The number (and %) of the onco-proteins3 (33.33 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)9 (25.00 %)
The number (and %) of affected PPIs7 (77.78 %)
The number of possible different fusions2
PPI diameter2
PPI radiusinf
The average degree of PPI1.556
Assortativity coefficient0
The network average Clustering coefficient0.000
The number (and %) of a zero Clustering coefficients9 (100.00 %)
The number (and %) of a zero Betweenness Centrality8 (88.89 %)


List of the fusions

PPI for parental proteins: ZNF549,CTSK All fusions
Proteins found in more fusions ERBIN (see 4 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Domains (Pfam, InterPro, SMART): description
1 ZNF549interactor000NA
2 CTSKparental protein7042.000Inhibitor_I29 (PF08246, IPR013201, SM00848): Cathepsin propeptide inhibitor domain (I29)
Peptidase_C1 (PF00112, IPR000668, SM00645): Papain family cysteine protease
3 ARID4Binteractor100ARID (PF01388, IPR001606, SM00501): ARID/BRIGHT DNA binding domain
CDC45 (PF02724, IPR003874): CDC45-like protein
DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755)
E7 (PF00527, IPR000148): E7 protein, Early protein
NOA36 (PF06524, IPR010531): NOA36 protein
PWWP (PF00855, IPR000313, SM00293): PWWP domain
RBB1NT (PF08169, IPR012603): RBB1NT (NUC162) domain
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
Tudor-knot (PF11717, IPR025995): RNA binding activity-knot of a chromodomain
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
4 C18orf25interactor100RNF111_N (PF15303, IPR029306): E3 ubiquitin-protein ligase Arkadia N-terminus
5 CTSVinteractor100Inhibitor_I29 (PF08246, IPR013201, SM00848): Cathepsin propeptide inhibitor domain (I29)
Peptidase_C1 (PF00112, IPR000668, SM00645): Papain family cysteine protease
6 ERBINoncoprotein200LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
7 FGFR3oncoprotein200I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Ig_3 (PF13927): Immunoglobulin domain
Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
8 LIG4interactor100APG17 (PF04108, IPR007240): Autophagy protein Apg17
BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
DNA_ligase_A_C (PF04679, IPR012309): ATP dependent DNA ligase C terminal region
DNA_ligase_A_M (PF01068, IPR012310): ATP dependent DNA ligase domain
DNA_ligase_A_N (PF04675, IPR012308): DNA ligase N terminus
DNA_ligase_IV (PF11411, IPR021536): DNA ligase IV
RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain
9 SERPINB3oncoprotein100Serpin (PF00079, IPR023796, SM00093): Serpin (serine protease inhibitor)

B a c k    t o    T o p ⇑