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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins LRRC6, IMMP2L (from a repository: Sat Jul 13 16:02:33 2019)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)5
The number (and %) of the onco-proteins1 (20.00 %)
The number (and %) of the tumor suppressors1 (20.00 %)
Total number of binary PPIs (saturation %)5 (50.00 %)
The number (and %) of affected PPIs3 (60.00 %)
The number of possible different fusions2
PPI diameter2
PPI radiusinf
The average degree of PPI1.200
Assortativity coefficient0
The network average Clustering coefficient0.000
The number (and %) of a zero Clustering coefficients5 (100.00 %)
The number (and %) of a zero Betweenness Centrality4 (80.00 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: LRRC6,IMMP2L All fusions
Proteins found in more fusions HNRNPD (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 LRRC6parental protein202.000DUF3340 (PF11818, IPR020992): C-terminal domain of tail specific protease (DUF3340)
DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915)
LRR_9 (PF14580): Leucine-rich repeat
MRP-63 (PF14978, IPR016576): Mitochondrial ribosome protein 63
2 IMMP2Lparental protein100Peptidase_S24 (PF00717, IPR019759): Peptidase S24-like
Peptidase_S26 (PF10502, IPR019533): Signal peptidase, peptidase S26
DUF2798 (PF11391, IPR021529): Protein of unknown function (DUF2798)
3 CACYBPinteractor200CS (PF04969, IPR007052): CS domain
SGS (PF05002, IPR007699): SGS domain
Siah-Interact_N (PF09032, IPR015120): Siah interacting protein, N terminal
4 HNRNPDoncoprotein200CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain
NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Keratin_2_head (PF16208, IPR032444): Keratin type II head
5 SCRIBsuppressor100Hormone_3 (PF00159, IPR001955): Pancreatic hormone peptide
LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
SDA1 (PF05285, IPR007949): SDA1
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
LRR_9 (PF14580): Leucine-rich repeat
AbLIM_anchor (PF16182, IPR032402): Putative adherens-junction anchoring region of AbLIM

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