Find Fusion Network

Enter
Fusion ID:
Protein names:


Level of PPIs:
or Upload text file:
Update repository
Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins HYAL4, MT1G (from a repository: Fri Aug 23 10:43:53 2019)
Examples

Cytoscape Web will replace the contents your graph
PPI Properties:

Click on nodes
or edges

Layout Tree
Circle
Radial
Force Directed
Preset
Export graph
PDF file
SVG file
SIF file
XML file
GraphML file

Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)6
The number (and %) of the onco-proteins1 (16.67 %)
The number (and %) of the tumor suppressors2 (33.33 %)
Total number of binary PPIs (saturation %)6 (40.00 %)
The number (and %) of affected PPIs4 (66.67 %)
The number of possible different fusions2
PPI diameter2
PPI radiusinf
The average degree of PPI1.333
Assortativity coefficient0
The network average Clustering coefficient0.000
The number (and %) of a zero Clustering coefficients6 (100.00 %)
The number (and %) of a zero Betweenness Centrality4 (66.67 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: HYAL4,MT1G All fusions
Proteins found in more fusions TP53 (see 3 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 HYAL4parental protein202.000EGF (PF00008, IPR000742, SM00181): EGF-like domain
Glyco_hydro_56 (PF01630, IPR018155): Hyaluronidase
Prion_bPrPp (PF11587, IPR025860): Major prion protein bPrPp - N terminal
CooC_C (PF15976, IPR031917): CS1-pili formation C-terminal
2 MT1Gparental protein202.000Metallothio (PF00131, IPR003019): Metallothionein
3 IARS2interactor100Anticodon_1 (PF08264, IPR013155): Anticodon-binding domain of tRNA
tRNA-synt_1 (PF00133, IPR002300): tRNA synthetases class I (I, L, M and V)
zf-FPG_IleRS (PF06827, IPR010663): Zinc finger found in FPG and IleRS
4 SHBGoncoprotein200Laminin_G_1 (PF00054, IPR001791): Laminin G domain
Laminin_G_2 (PF02210, IPR001791): Laminin G domain
5 SPINK7suppressor100Kazal_1 (PF00050, IPR002350): Kazal-type serine protease inhibitor domain
6 TP53suppressor200DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
P53 (PF00870, IPR011615): P53 DNA-binding domain
P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif

B a c k    t o    T o p ⇑