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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)179
The number (and %) of the onco-proteins29 (16.20 %)
The number (and %) of the tumor suppressors5 (2.79 %)
Total number of binary PPIs (saturation %)341 (2.14 %)
The number (and %) of affected PPIs178 (52.20 %)
The number of possible different fusions16
PPI diameter4
PPI radius2
The average degree of PPI3.307
Assortativity coefficient-0.4869
The network average Clustering coefficient0.348
The number (and %) of a zero Clustering coefficients92 (51.40 %)
The number (and %) of a zero Betweenness Centrality129 (72.07 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: MAN2B2,MTUS2 All fusions
Proteins found in more fusions AES (see 3 fusions); MAPRE1 (see 1 fusions); NDEL1 (see 1 fusions); LNX1 (see 1 fusions); CRY2 (see 3 fusions); CEP57L1 (see 1 fusions); FCHSD2 (see 1 fusions); C19orf66 (see 2 fusions); KAT5 (see 3 fusions); ITSN1 (see 2 fusions); HDAC4 (see 1 fusions); RPA1 (see 1 fusions); THAP7 (see 1 fusions); WAC (see 4 fusions); SNW1 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 MAN2B2parental protein31.0000Alpha-mann_mid (PF09261, IPR015341, SM00872): Alpha mannosidase middle domain
Glyco_hydro_38 (PF01074, IPR000602): Glycosyl hydrolases family 38 N-terminal domain
Glyco_hydro_38C (PF07748, IPR011682): Glycosyl hydrolases family 38 C-terminal domain
2 MTUS2parental protein1750.00730647.216DUF496 (PF04363, IPR007458): Protein of unknown function (DUF496)
RNA_pol_Rpb1_R (PF05001, IPR000684): RNA polymerase Rpb1 C-terminal repeat
FAM184 (PF15665): Family with sequence similarity 184, A and B
3 AENinteractor40.5001.400RNase_T (PF00929, IPR013520): Exonuclease
4 AESprotein found in more fusions120.20038.000TLE_N (PF03920, IPR005617): Groucho/TLE N-terminal Q-rich domain
5 AFF4oncoprotein100AF-4 (PF05110, IPR007797): AF-4 proto-oncoprotein
6 ALS2CR11interactor100DUF2680 (PF10925, IPR024485): Protein of unknown function (DUF2680)
ALS2CR11 (PF15729, IPR031462): Amyotrophic lateral sclerosis 2 candidate 11
7 AQP1interactor200MIP (PF00230, IPR000425): Major intrinsic protein
8 ARNT2interactor40.5001.667HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
PAS (PF00989, IPR013767, SM00091): PAS fold
PAS_3 (PF08447, IPR013655): PAS fold
PAP2 (PF01569, IPR000326, SM00014): PAP2 superfamily
9 BMP7interactor30421.416TGFb_propeptide (PF00688, IPR001111): TGF-beta propeptide
TGF_beta (PF00019, IPR001839, SM00204): Transforming growth factor beta like domain
10 BYSLinteractor50.4003.067Bystin (PF05291, IPR007955): Bystin
MEA1 (PF06910, IPR009685): Male enhanced antigen 1 (MEA1)
11 C14orf105interactor30.6671.000DUF4619 (PF15398, IPR029235): Domain of unknown function (DUF4619)
12 C19orf66protein found in more fusions31.0000UPF0515 (PF15135, IPR026795): Uncharacterised protein UPF0515
13 C1orf109interactor60.4676.500CK2S (PF15011, IPR029159): Casein Kinase 2 substrate
14 C1orf216interactor21.0000DUF4653 (PF15546, IPR027812): Domain of unknown function (DUF4653)
15 C21orf58interactor100DUF4587 (PF15248, IPR027904): Domain of unknown function (DUF4587)
16 C8orf34interactor200Glycoprotein_G (PF00802, IPR000925): Pneumovirus attachment glycoprotein G
17 CATIPinteractor200RIIa (PF02197, IPR003117, SM00394): Regulatory subunit of type II PKA R-subunit
18 CATSPER1interactor200Ion_trans (PF00520, IPR005821): Ion transport protein
MMM1 (PF10296, IPR019411): Maintenance of mitochondrial morphology protein 1
19 CBX8interactor31.0000Atrophin-1 (PF03154, IPR002951): Atrophin-1 family
Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
RBR (PF17208): RNA binding Region
CBX7_C (PF17218): CBX family C-terminal motif
20 CCDC116interactor100DUF4702 (PF15774, IPR031532): Domain of unknown function (DUF4702)
21 CCDC146interactor21.0000ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
DUF724 (PF05266, IPR007930): Protein of unknown function (DUF724)
DUF745 (PF05335, IPR007999): Protein of unknown function (DUF745)
ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
Med21 (PF11221, IPR021384): Subunit 21 of Mediator complex
Kinetocho_Slk19 (PF12709, IPR024312): Central kinetochore-associated
FOXP-CC (PF16159, IPR032354): FOXP coiled-coil domain
BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2
22 CCDC17interactor100zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
PRIMA1 (PF16101): Proline-rich membrane anchor 1
TolA_bind_tri (PF16331, IPR032519): TolA binding protein trimerisation
23 CCDC60interactor100DUF4698 (PF15769, IPR031526): Domain of unknown function (DUF4698)
24 CCHCR1interactor40.6671.000HCR (PF07111, IPR009800): Alpha helical coiled-coil rod protein (HCR)
25 CDC20Binteractor100WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
26 CDC73suppressor21.0000CDC73_C (PF05179, IPR007852): RNA pol II accessory factor, Cdc73 family, C-terminal
CDC73_N (PF16050, IPR032041): Paf1 complex subunit CDC73 N-terminal
27 CDK18oncoprotein100APH (PF01636, IPR002575): Phosphotransferase enzyme family
Pkinase (PF00069, IPR000719): Protein kinase domain
28 CDK5R1oncoprotein21.0000CDK5_activator (PF03261, IPR004944): Cyclin-dependent kinase 5 activator protein
29 CDKL3interactor100Pkinase (PF00069, IPR000719): Protein kinase domain
30 CEP57L1protein found in more fusions80.28610.833Cep57_MT_bd (PF06657, IPR024957): Centrosome microtubule-binding domain of Cep57
XhlA (PF10779, IPR019715): Haemolysin XhlA
YqzE (PF14038, IPR025622): YqzE-like protein
Cep57_CLD (PF14073, IPR025913): Centrosome localisation domain of Cep57
31 CEP95interactor100HSCB_C (PF07743, IPR009073): HSCB C-terminal oligomerisation domain
IncA (PF04156, IPR007285): IncA protein
DUF4094 (PF13334, IPR025298): Domain of unknown function (DUF4094)
DUF4718 (PF15842, IPR031695): Domain of unknown function (DUF4718)
32 CERKinteractor30.6671.000DAGK_cat (PF00781, IPR001206, SM00046): Diacylglycerol kinase catalytic domain
33 COG2interactor100COG2 (PF06148, IPR024602): COG (conserved oligomeric Golgi) complex component, COG2
COG5 (PF10392, IPR019465): Golgi transport complex subunit 5
DUF3510 (PF12022, IPR024603): Domain of unknown function (DUF3510)
Syntaxin_2 (PF14523): Syntaxin-like protein
34 CREB5interactor200bZIP_1 (PF00170, IPR004827): bZIP transcription factor
Zip (PF02535, IPR003689): ZIP Zinc transporter
Shisa (PF13908, IPR026910): Wnt and FGF inhibitory regulator
35 CRY2protein found in more fusions200DNA_photolyase (PF00875, IPR006050): DNA photolyase
FAD_binding_7 (PF03441, IPR005101): FAD binding domain of DNA photolyase
36 CTSZinteractor20144.650Peptidase_C1 (PF00112, IPR000668, SM00645): Papain family cysteine protease
37 CWF19L2interactor21.0000CwfJ_C_1 (PF04677, IPR006768): Protein similar to CwfJ C-terminus 1
CwfJ_C_2 (PF04676, IPR006767): Protein similar to CwfJ C-terminus 2
DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755)
Pap_E4 (PF02711, IPR003861): E4 protein
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
DUF4519 (PF15012, IPR027960): Domain of unknown function (DUF4519)
MRI (PF15325, IPR028278): Modulator of retrovirus infection
38 CXCL11interactor100IL8 (PF00048, IPR001811, SM00199): Small cytokines (intecrine/chemokine), interleukin-8 like
39 CXCL16interactor100FeThRed_A (PF02941, IPR004207): Ferredoxin thioredoxin reductase variable alpha chain
40 DCDC2Binteractor21.0000DCX (PF03607, IPR003533, SM00537): Doublecortin
41 DCTN4interactor100Dynactin_p62 (PF05502, IPR008603): Dynactin p62 family
42 DLGAP5interactor100GKAP (PF03359, IPR005026): Guanylate-kinase-associated protein (GKAP) protein
43 DMRT3interactor100DM (PF00751, IPR001275, SM00301): DM DNA binding domain
DMA (PF03474, IPR005173): DMRTA motif
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
44 DOCK2oncoprotein21.0000DHR-2 (PF06920, IPR010703): Dock homology region 2
DUF1539 (PF07560, IPR011436): Domain of Unknown Function (DUF1539)
DOCK-C2 (PF14429, IPR027007): C2 domain in Dock180 and Zizimin proteins
SH3_9 (PF14604, IPR001452): Variant SH3 domain
DOCK_N (PF16172, IPR032376): DOCK N-terminus
45 DTNBinteractor31.0000EF-hand_2 (PF09068, IPR015153): EF hand
EF-hand_3 (PF09069, IPR015154): EF-hand
Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain
Ax_dynein_light (PF10211, IPR019347): Axonemal dynein light chain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
SOGA (PF11365, IPR027881): Protein SOGA
46 FAM110Ainteractor100FAM110_C (PF14160, IPR025741): Centrosome-associated C terminus
FAM110_N (PF14161, IPR025739): Centrosome-associated N terminus
47 FAM13Cinteractor200Mnd1 (PF03962, IPR005647): Mnd1 family
SlyX (PF04102, IPR007236): SlyX
MRI (PF15325, IPR028278): Modulator of retrovirus infection
Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease
48 FAM161Ainteractor40.6670.333YajC (PF02699, IPR003849): Preprotein translocase subunit
UPF0564 (PF10595, IPR019579): Uncharacterised protein family UPF0564
49 FAM71E2interactor100Ndc1_Nup (PF09531, IPR019049): Nucleoporin protein Ndc1-Nup
DUF3699 (PF12480, IPR022168): Protein of unknown function (DUF3699)
50 FAM74A4interactor21.0000NA
51 FAM90A1interactor21.0000zf-CCHC_6 (PF15288): Zinc knuckle
52 FBXL18interactor21.0000LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
F-box (PF00646, IPR001810, SM00256): F-box domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
53 FBXO34interactor100BTK (PF00779, IPR001562, SM00107): BTK motif
F-box-like (PF12937, IPR001810): F-box-like
54 FBXO6interactor90.111636.584FBA (PF04300, IPR007397): F-box associated region
F-box-like (PF12937, IPR001810): F-box-like
55 FCHSD2protein found in more fusions40.6671.000Cortex-I_coil (PF09304, IPR015383): Cortexillin I, coiled coil
DivIC (PF04977, IPR007060): Septum formation initiator
FCH (PF00611, IPR001060, SM00055): Fes/CIP4, and EFC/F-BAR homology domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
DUF4665 (PF15679, IPR031389): Domain of unknown function (DUF4665)
Rit1_C (PF17184): Rit1 N-terminal domain
56 FHL3interactor120.20043.667LIM (PF00412, IPR001781, SM00132): LIM domain
Med27 (PF11571, IPR021627): Mediator complex subunit 27
57 FNDC11interactor100MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
58 GAL3ST2interactor100Gal-3-0_sulfotr (PF06990, IPR009729): Galactose-3-O-sulfotransferase
59 GOLGA2P11interactor100NA
60 GTF2Iinteractor30.667144.650GTF2I (PF02946, IPR004212): GTF2I-like repeat
61 GTPBP10interactor100GTP1_OBG (PF01018, IPR006169): GTP1/OBG
GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
MMR_HSR1 (PF01926, IPR006073): 50S ribosome-binding GTPase
62 HAUS1interactor50.5002.333THP2 (PF09432, IPR018557): Tho complex subunit THP2
XhlA (PF10779, IPR019715): Haemolysin XhlA
DUF3496 (PF12001, IPR021885): Domain of unknown function (DUF3496)
63 HCKoncoprotein100Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
64 HDAC4oncoprotein200Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein
Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
65 HSF2interactor100HAP1_N (PF04849, IPR006933): HAP1 N-terminal conserved region
Vert_HS_TF (PF06546, IPR010542): Vertebrate heat shock transcription factor
HSF_DNA-bind (PF00447, IPR000232, SM00415): HSF-type DNA-binding
HMMR_C (PF15908, IPR031794): Hyaluronan mediated motility receptor C-terminal
66 IQCEoncoprotein100CaMBD (PF02888, IPR004178, SM01053): Calmodulin binding domain
CHD5 (PF04420, IPR028945): CHD5-like protein
IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Med10 (PF09748, IPR019145): Transcription factor subunit Med10 of Mediator complex
SOGA (PF11365, IPR027881): Protein SOGA
67 ITGB5interactor100EGF_2 (PF07974, IPR013111): EGF-like domain
Integrin_b_cyt (PF08725, IPR014836): Integrin beta cytoplasmic domain
Integrin_B_tail (PF07965, IPR012896): Integrin beta tail domain
Integrin_beta (PF00362, IPR002369, SM00187): Integrin beta chain VWA domain
PSI_integrin (PF17205): Integrin plexin domain
68 ITSN1protein found in more fusions40.6671.000C2 (PF00168, IPR000008, SM00239): C2 domain
VIT1 (PF01988, IPR008217): VIT family
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
FmdE (PF02663, IPR003814): FmdE, Molybdenum formylmethanofuran dehydrogenase operon
GSH_synthase (PF03199, IPR004887): Eukaryotic glutathione synthase
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand
DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915)
SH3_9 (PF14604, IPR001452): Variant SH3 domain
DUF4748 (PF15932, IPR031833): Domain of unknown function (DUF4748)
INTAP (PF16617): Intersectin and clathrin adaptor AP2 binding region
PH_13 (PF16652, IPR001849): Pleckstrin homology domain
69 KAT5suppressor40.6671.000MOZ_SAS (PF01853, IPR002717): MOZ/SAS family
Tudor-knot (PF11717, IPR025995): RNA binding activity-knot of a chromodomain
70 KIF1Ainteractor100FHA (PF00498, IPR000253, SM00240): FHA domain
IncA (PF04156, IPR007285): IncA protein
PH (PF00169, IPR001849, SM00233): PH domain
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
KIF1B (PF12423, IPR022140): Kinesin protein 1B
Sox_N (PF12444, IPR022151): Sox developmental protein N terminal
DUF3694 (PF12473, IPR022164): Kinesin protein
Kinesin_assoc (PF16183, IPR032405): Kinesin-associated
71 KIF2Cinteractor50.5002.667Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
72 LENG1interactor30.6670.333Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR
DUF3323 (PF11796, IPR024466): Protein of unknown function N-terminus (DUF3323)
73 LIMS2interactor100LIM (PF00412, IPR001781, SM00132): LIM domain
MSSP (PF03940, IPR005634): Male specific sperm protein
zf-RRN7 (PF11781, IPR021752): Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7
zf-C4pol (PF14260, IPR025687): C4-type zinc-finger of DNA polymerase delta
74 LINC00636interactor100NA
75 LMO2oncoprotein70.3339.067CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
LIM (PF00412, IPR001781, SM00132): LIM domain
76 LNX1protein found in more fusions90.28619.333PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
zf-rbx1 (PF12678, IPR024766): RING-H2 zinc finger domain
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
77 LOC153684interactor100NA
78 LRR1interactor21.0000LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
79 LYSMD1interactor100LysM (PF01476, IPR018392, SM00257): LysM domain
80 MAGEA8interactor21.0000MAGE (PF01454, IPR002190): MAGE family
MAGE_N (PF12440, IPR021072): Melanoma associated antigen family N terminal
81 MAPRE1oncoprotein70.33312.979CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
EB1 (PF03271, IPR004953): EB1-like C-terminal motif
SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
82 MARK4oncoprotein21.0000KA1 (PF02149, IPR001772): Kinase associated domain 1
Pkinase (PF00069, IPR000719): Protein kinase domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
83 MFAP1interactor60.3337.567MFAP1 (PF06991, IPR009730): Microfibril-associated/Pre-mRNA processing
DUF3464 (PF11947, IPR021855): Protein of unknown function (DUF3464)
SIR4_SID (PF16991, IPR031556): Sir4 SID domain
84 MTMR6interactor100DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain
GRAM (PF02893, IPR004182, SM00568): GRAM domain
Myotub-related (PF06602, IPR010569): Myotubularin-like phosphatase domain
85 NAAAinteractor40.50097.416CBAH (PF02275, IPR003199): Linear amide C-N hydrolases, choloylglycine hydrolase family
NAAA-beta (PF15508, IPR029130): beta subunit of N-acylethanolamine-hydrolyzing acid amidase
86 NDEL1protein found in more fusions120.18245.000HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
87 NDOR1interactor200FAD_binding_1 (PF00667, IPR003097): FAD binding domain
Flavodoxin_1 (PF00258, IPR008254): Flavodoxin
NAD_binding_1 (PF00175, IPR001433): Oxidoreductase NAD-binding domain
88 NELFEinteractor21.0000DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510)
FLO_LFY (PF01698, IPR002910): Floricaula / Leafy protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
ANAPC15 (PF15243, IPR026182): Anaphase-promoting complex subunit 15
89 NUBPLinteractor100ParA (PF10609, IPR019591): NUBPL iron-transfer P-loop NTPase
90 NUDT10interactor100NUDIX (PF00293, IPR000086): NUDIX domain
91 ODF1interactor21.0000HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family
DUF2654 (PF10849, IPR022558): Protein of unknown function (DUF2654)
92 PDE4DIPoncoprotein230.095222.167ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
Med9 (PF07544, IPR011425): RNA polymerase II transcription mediator complex subunit 9
DivIC (PF04977, IPR007060): Septum formation initiator
DUF1220 (PF06758, IPR010630, SM01148): Repeat of unknown function (DUF1220)
DUF1515 (PF07439, IPR010889): Protein of unknown function (DUF1515)
IncA (PF04156, IPR007285): IncA protein
Cnn_1N (PF07989, IPR012943): Centrosomin N-terminal motif 1
Mod_r (PF07200, IPR009851): Modifier of rudimentary (Mod(r)) protein
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
SlyX (PF04102, IPR007236): SlyX
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
Atg14 (PF10186, IPR018791): Vacuolar sorting 38 and autophagy-related subunit 14
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
DUF4140 (PF13600, IPR025554): N-terminal domain of unknown function (DUF4140)
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
Nup54 (PF13874, IPR025712): Nucleoporin complex subunit 54
FAM76 (PF16046, IPR032017): FAM76 protein
MPS2 (PF17060, IPR031433): Monopolar spindle protein 2
93 PIN1suppressor30.6671.000Rotamase (PF00639, IPR000297): PPIC-type PPIASE domain
WW (PF00397, IPR001202, SM00456): WW domain
94 PKP2interactor21.0000Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
DUF383 (PF04063, IPR007205): Domain of unknown function (DUF383)
95 PLK4interactor31.0000ABC1 (PF03109, IPR004147): ABC1 family
Pkinase (PF00069, IPR000719): Protein kinase domain
POLO_box (PF00659, IPR000959): POLO box duplicated region
DUF4520 (PF15016, IPR027865): Domain of unknown function (DUF4520)
96 PLSCR4interactor100Scramblase (PF03803, IPR005552): Scramblase
97 POLDIP2interactor21.0000DUF525 (PF04379, IPR007474): ApaG domain
YccV-like (PF08755, IPR011722, SM00992): Hemimethylated DNA-binding protein YccV like
98 POLDIP3interactor100RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
99 PPHLN1interactor100Lge1 (PF11488): Transcriptional regulatory protein LGE1
HERV-K_REC (PF15695): Rec (regulator of expression encoded by corf) of HERV-K-113
100 PPP1R18interactor21.0000Totivirus_coat (PF05518, IPR008871): Totivirus coat protein
DUF4124 (PF13511, IPR025392): Domain of unknown function (DUF4124)
Phostensin (PF13914, IPR025907): Phostensin PP1-binding and SH3-binding region
Phostensin_N (PF13916, IPR025903): PP1-regulatory protein, Phostensin N-terminal
101 PRKAA1suppressor40.5003.000Pkinase (PF00069, IPR000719): Protein kinase domain
AdenylateSensor (PF16579, IPR032270): Adenylate sensor of SNF1-like protein kinase
102 PRPF31interactor70.3339.333Nop (PF01798, IPR002687): snoRNA binding domain, fibrillarin
Cytokin_check_N (PF10407, IPR018844): Cdc14 phosphatase binding protein N-terminus
Prp31_C (PF09785, IPR019175): Prp31 C terminal domain
103 PSMA1interactor60.300174.681Proteasome (PF00227, IPR001353): Proteasome subunit
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
104 PTPMT1interactor40.333151.650DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain
105 RAB3IL1interactor200Sec2p (PF06428, IPR009449): GDP/GTP exchange factor Sec2p
106 RGS2oncoprotein100RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain
107 RHPN1interactor100BRO1 (PF03097, IPR004328, SM01041): BRO1-like domain
HR1 (PF02185, IPR011072, SM00742): Hr1 repeat
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
108 RIBC2interactor100RIB43A (PF05914, IPR008805): RIB43A
109 ROBO3interactor21.0000Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
Pur_ac_phosph_N (PF16656, IPR015914): Purple acid Phosphatase, N-terminal domain
110 RPA1suppressor60.400167.970Rep-A_N (PF04057, IPR007199): Replication factor-A protein 1, N-terminal domain
Rep_fac-A_C (PF08646, IPR013955): Replication factor-A C terminal domain
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
REPA_OB_2 (PF16900, IPR031657): Replication protein A OB domain
111 RPL9interactor40.5004.075Ribosomal_L6 (PF00347, IPR020040): Ribosomal protein L6
112 RTP5interactor21.0000zf-3CxxC (PF13695, IPR027377): Zinc-binding domain
113 SCELinteractor100FlaF (PF07309, IPR010845): Flagellar protein FlaF
LIM (PF00412, IPR001781, SM00132): LIM domain
IFT43 (PF15305, IPR029302): Intraflagellar transport protein 43
114 SDCBPinteractor40.8330.333PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
115 SELENOMinteractor100Sep15_SelM (PF08806, IPR014912): Sep15/SelM redox domain
DUF4148 (PF13663, IPR025421): Domain of unknown function (DUF4148)
116 SETD5interactor100FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid)
SET (PF00856, IPR001214, SM00317): SET domain
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
DUF3807 (PF12720, IPR024526): Protein of unknown function (DUF3807)
117 SH2D4Ainteractor21.0000Cytochrom_NNT (PF03264, IPR005126): NapC/NirT cytochrome c family, N-terminal region
Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1
Peptidase_S49_N (PF08496, IPR013703): Peptidase family S49 N-terminal
SH2 (PF00017, IPR000980, SM00252): SH2 domain
DUF2039 (PF10217, IPR019351): Uncharacterized conserved protein (DUF2039)
118 SH3RF2interactor100SH3_2 (PF07653, IPR011511): Variant SH3 domain
TUDOR (PF00567, IPR002999, SM00333): Tudor domain
UPF0547 (PF10571, IPR018886): Uncharacterised protein family UPF0547
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
SH3_9 (PF14604, IPR001452): Variant SH3 domain
119 SIAEinteractor31.0000SASA (PF03629, IPR005181): Carbohydrate esterase, sialic acid-specific acetylesterase
120 SLC23A1interactor100Xan_ur_permease (PF00860, IPR006043): Permease family
121 SLC25A6interactor20144.650Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
122 SLIRPinteractor21.0000RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
123 SMARCE1interactor100DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
GCN5L1 (PF06320, IPR009395): GCN5-like protein 1 (GCN5L1)
Ndc1_Nup (PF09531, IPR019049): Nucleoporin protein Ndc1-Nup
HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
Ferlin_C (PF16165, IPR032362): Ferlin C-terminus
124 SNAI1oncoprotein100zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger
125 SNHG11interactor100NA
126 SNRPAinteractor200RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
127 SNRPB2interactor30.6671.000DUF1027 (PF06265, IPR009370): Protein of unknown function (DUF1027)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
128 SNW1protein found in more fusions100.25031.579SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
SIR4_SID (PF16991, IPR031556): Sir4 SID domain
129 SPATA8interactor21.0000NA
130 SPG7oncoprotein21.0000AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
FtsH_ext (PF06480, IPR011546): FtsH Extracellular
Peptidase_M41 (PF01434, IPR000642): Peptidase family M41
AAA_22 (PF13401, IPR003593): AAA domain
131 STK16interactor40.6670.500Pkinase (PF00069, IPR000719): Protein kinase domain
132 SYT6interactor200C2 (PF00168, IPR000008, SM00239): C2 domain
133 TAF13interactor21.0000TFIID-18kDa (PF02269, IPR003195): Transcription initiation factor IID, 18kD subunit
134 TFGoncoprotein40.6671.000ARS2 (PF04959, IPR007042): Arsenite-resistance protein 2
MucBP (PF06458, IPR009459): MucBP domain
PB1 (PF00564, IPR000270, SM00666): PB1 domain
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
135 THAP7protein found in more fusions40.6671.000THAP (PF05485, IPR006612, SM00980): THAP domain
Tho2 (PF11262, IPR021418): Transcription factor/nuclear export subunit protein 2
136 TP53RKoncoprotein100APH (PF01636, IPR002575): Phosphotransferase enzyme family
Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family
137 TRIM42interactor70.33311.385CHDCT2 (PF08074, IPR012957): CHDCT2 (NUC038) domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
138 TSGA10IPinteractor100Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
139 TSHZ3interactor100LMP (PF04778, IPR006864): LMP repeated region
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies)
zf-met (PF12874): Zinc-finger of C2H2 type
zf-C2HE (PF16278, IPR032566): C2HE / C2H2 / C2HC zinc-binding finger
140 TULP2interactor100Tub (PF01167, IPR000007): Tub family
Tub_N (PF16322, IPR005398): Tubby N-terminal
141 TXN2interactor21.0000Thioredoxin (PF00085, IPR013766): Thioredoxin
142 USP2interactor30.6671.000UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
143 WACprotein found in more fusions31.0000DUF1319 (PF07028, IPR010746): Protein of unknown function (DUF1319)
MGC-24 (PF05283, IPR007947): Multi-glycosylated core protein 24 (MGC-24), sialomucin
WW (PF00397, IPR001202, SM00456): WW domain
MDFI (PF15316, IPR026134): MyoD family inhibitor
CCDC106 (PF15794, IPR031591): Coiled-coil domain-containing protein 106
144 WDYHV1interactor100Nt_Gln_amidase (PF09764, IPR023128): N-terminal glutamine amidase
145 ZBTB38interactor30.6671.000BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-met (PF12874): Zinc-finger of C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-C2H2_7 (PF15269): Zinc-finger
zf-C2H2_8 (PF15909, IPR031799): C2H2-type zinc ribbon
146 ZC2HC1Cinteractor100zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger
zf-C2HC_2 (PF13913): zinc-finger of a C2HC-type
147 ZFC3H1interactor100Bap31 (PF05529, IPR008417): B-cell receptor-associated protein 31-like
LMBR1 (PF04791, IPR006876): LMBR1-like membrane protein
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
DUF2277 (PF10041, IPR018735): Uncharacterized conserved protein (DUF2277)
zf-C3H1 (PF10650, IPR019607, SM00356): Putative zinc-finger domain
DUF2570 (PF10828, IPR022538): Protein of unknown function (DUF2570)
TPR_14 (PF13428): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
FNIP_N (PF14636, IPR028084): Folliculin-interacting protein N-terminus
148 ZFP2interactor100zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
Zf_RING (PF16744, IPR031946): KIAA1045 RING finger
149 ZFP64oncoprotein60.3337.000zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain
zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger
zf-C2HE (PF16278, IPR032566): C2HE / C2H2 / C2HC zinc-binding finger
150 ZFYVE21interactor31.0000FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger
ZFYVE21_C (PF16696, IPR032031): Zinc finger FYVE domain-containing protein 21 C-terminus
151 ZMAT2interactor100Cgr1 (PF03879, IPR005579): Cgr1 family
zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding
152 ZNF136interactor100KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
153 ZNF20interactor100KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
YhfH (PF14149, IPR025432): YhfH-like protein
154 ZNF224interactor100KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
155 ZNF232interactor100SCAN (PF02023, IPR003309, SM00431): SCAN domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
156 ZNF250interactor31.0000KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
157 ZNF3interactor200KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
158 ZNF329interactor100zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
159 ZNF337interactor100KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
160 ZNF410interactor100Toxin_18 (PF08087, IPR012623): Conotoxin O-superfamily
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
161 ZNF415interactor100KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
162 ZNF417interactor40.5003.000A2L_zn_ribbon (PF08792, IPR014900): A2L zinc ribbon domain
C1_4 (PF07975, IPR004595, SM01047): TFIIH C1-like domain
KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
163 ZNF426interactor100KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
164 ZNF439interactor100KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger
zf-C2HC_2 (PF13913): zinc-finger of a C2HC-type
165 ZNF440interactor100KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-C2HC_2 (PF13913): zinc-finger of a C2HC-type
166 ZNF490interactor21.0000KRAB (PF01352, IPR001909, SM00349): KRAB box
TF_Zn_Ribbon (PF08271, IPR013137): TFIIB zinc-binding
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger
167 ZNF557interactor100KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
168 ZNF572interactor21.0000C1_2 (PF03107, IPR004146): C1 domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
169 ZNF581interactor30.6671.000zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
170 ZNF587interactor30.6671.000KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
171 ZNF599interactor21.0000KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
172 ZNF607interactor100KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger
173 ZNF624interactor100KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
174 ZNF655interactor100Asr (PF06392, IPR009435): Acid shock protein repeat
Chordopox_RPO7 (PF05864, IPR008448): Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7)
zf-AN1 (PF01428, IPR000058, SM00154): AN1-like Zinc finger
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
175 ZNF670interactor100KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
176 ZNF785interactor100ADK_lid (PF05191, IPR007862): Adenylate kinase, active site lid
KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
Lar_restr_allev (PF14354): Restriction alleviation protein Lar
177 ZNF844oncoprotein21.0000KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
DUF3268 (PF11672, IPR021686): zinc-finger-containing domain
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
178 ZSCAN12interactor200Zn-ribbon_8 (PF09723, IPR013429, SM00834): Zinc ribbon domain
SCAN (PF02023, IPR003309, SM00431): SCAN domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
179 ZSCAN26interactor31.0000C1_4 (PF07975, IPR004595, SM01047): TFIIH C1-like domain
SCAN (PF02023, IPR003309, SM00431): SCAN domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain

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