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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)85
The number (and %) of the onco-proteins19 (22.35 %)
The number (and %) of the tumor suppressors7 (8.24 %)
Total number of binary PPIs (saturation %)315 (8.82 %)
The number (and %) of affected PPIs85 (26.98 %)
The number of possible different fusions8
PPI diameter4
PPI radius2
The average degree of PPI6.776
Assortativity coefficient-0.2635
The network average Clustering coefficient0.545
The number (and %) of a zero Clustering coefficients13 (15.29 %)
The number (and %) of a zero Betweenness Centrality27 (31.76 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: ERCC1,PHF8 All fusions
Proteins found in more fusions FANCG (see 1 fusions); APP (see 5 fusions); TOPBP1 (see 1 fusions); RARA (see 1 fusions); POLR2A (see 2 fusions); HCFC1 (see 2 fusions); MSH2 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 ERCC1parental protein300.1011977.802Rad10 (PF03834, IPR004579): Binding domain of DNA repair protein Ercc1 (rad10/Swi10)
HHH_5 (PF14520): Helix-hairpin-helix domain
2 PHF8parental protein550.0773712.963JmjC (PF02373, IPR003347, SM00558): JmjC domain, hydroxylase
PHD (PF00628, IPR019787, SM00249): PHD-finger
TSGP1 (PF07771, IPR011694): Tick salivary peptide group 1
AC_N (PF16214, IPR032628): Adenylyl cyclase N-terminal extracellular and transmembrane region
3 ACAT1interactor31.0000Thiolase_C (PF02803, IPR020617): Thiolase, C-terminal domain
Thiolase_N (PF00108, IPR020616): Thiolase, N-terminal domain
4 ANAPC1suppressor150.70545.254PC_rep (PF01851, IPR002015): Proteasome/cyclosome repeat
ANAPC1 (PF12859, IPR024990): Anaphase-promoting complex subunit 1
5 ANAPC2interactor130.87218.105ANAPC2 (PF08672, IPR014786, SM01013): Anaphase promoting complex (APC) subunit 2
Cullin (PF00888, IPR001373, SM00182): Cullin family
6 ANAPC4interactor140.84614.492ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
ANAPC4 (PF12896, IPR024790): Anaphase-promoting complex, cyclosome, subunit 4
7 ANAPC5interactor120.86411.536TPR_4 (PF07721, IPR011717): Tetratricopeptide repeat
ANAPC5 (PF12862, IPR026000): Anaphase-promoting complex subunit 5
TPR_6 (PF13174, IPR019734): Tetratricopeptide repeat
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_16 (PF13432): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
8 ANAPC7interactor150.80221.795TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
TPR_21 (PF09976, IPR018704): Tetratricopeptide repeat-like domain
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
TPR_7 (PF13176, IPR019734): Tetratricopeptide repeat
TPR_14 (PF13428): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
9 APPprotein found in more fusions140.167590.428APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding
Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP)
BUD22 (PF09073, IPR015158): BUD22
IncA (PF04156, IPR007285): IncA protein
Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus
APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
10 ASH2Linteractor60.7004.341SPRY (PF00622, IPR003877, SM00449): SPRY domain
PHD20L1_u1 (PF16660): PHD finger protein 20-like protein 1
11 BRAT1oncoprotein100HEAT (PF02985, IPR000357): HEAT repeat
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
12 C15orf40interactor100DUF167 (PF02594, IPR003746, SM01152): Uncharacterised ACR, YggU family COG1872
13 CCNA2oncoprotein80.52453.875Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain
Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
Cyclin_N2 (PF16500, IPR032447): N-terminal region of cyclin_N
14 CDC16interactor130.87218.105Dynein_light (PF01221, IPR001372): Dynein light chain type 1
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_17 (PF13431): Tetratricopeptide repeat
TPR_16 (PF13432): Tetratricopeptide repeat
SRP_TPR_like (PF17004, IPR031545): Putative TPR-like repeat
15 CDC20oncoprotein150.71429.578WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
16 CDC23interactor150.80221.795ANAPC8 (PF04049, IPR007192): Anaphase promoting complex subunit 8 / Cdc23
DUF772 (PF05598, IPR008490): Transposase domain (DUF772)
Menin (PF05053, IPR007747): Menin
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
TPR_6 (PF13174, IPR019734): Tetratricopeptide repeat
TPR_7 (PF13176, IPR019734): Tetratricopeptide repeat
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_14 (PF13428): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
17 CDC26interactor120.78846.210ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26
18 CDC27oncoprotein170.65845.974TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_12 (PF13424): Tetratricopeptide repeat
19 CDC5Linteractor130.333298.122OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat
Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component
Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain
20 CENPBinteractor21.0000CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain
CENP-B_N (PF04218, IPR007889): CENP-B N-terminal DNA-binding domain
DDE_1 (PF03184, IPR004875): DDE superfamily endonuclease
K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
RNA_polI_A34 (PF08208, IPR013240): DNA-directed RNA polymerase I subunit RPA34.5
Sporozoite_P67 (PF05642, IPR008845): Sporozoite P67 surface antigen
HTH_Tnp_Tc5 (PF03221, IPR006600, SM00674): Tc5 transposase DNA-binding domain
21 DNTTIP2interactor100BSP_II (PF05432, IPR008412): Bone sialoprotein II (BSP-II)
E7 (PF00527, IPR000148): E7 protein, Early protein
Fcf2 (PF08698, IPR014810): Fcf2 pre-rRNA processing
FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid)
22 EIF6interactor30.6671.154eIF-6 (PF01912, IPR002769, SM00654): eIF-6 family
23 ERCC4oncoprotein130.308136.554ERCC4 (PF02732, IPR006166, SM00891): ERCC4 domain
LUC7 (PF03194, IPR004882): LUC7 N_terminus
T2SSM_b (PF10741, IPR007690): Type II secretion system (T2SS), protein M subtype b
HHH_5 (PF14520): Helix-hairpin-helix domain
24 FANCGsuppressor40.6671.237BTAD (PF03704, IPR005158, SM01043): Bacterial transcriptional activator domain
Hpt (PF01627, IPR008207, SM00073): Hpt domain
TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_14 (PF13428): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
25 FZR1suppressor120.8794.347WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
26 GTF2H1oncoprotein70.42977.609BSD (PF03909, IPR005607, SM00751): BSD domain
PH_TFIIH (PF08567, IPR013876): TFIIH p62 subunit, N-terminal domain
27 H2AFYinteractor70.42916.366DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764)
Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
Macro (PF01661, IPR002589, SM00506): Macro domain
Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
28 H3F3Concoprotein100Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
29 HCFC1protein found in more fusions60.5006.667fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
Kelch_3 (PF13415): Galactose oxidase, central domain
Kelch_5 (PF13854): Kelch motif
zf-tcix (PF14952, IPR029269): Putative treble-clef, zinc-finger, Zn-binding
30 HIST1H3Ainteractor110.24492.750Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
31 HIST1H4Ainteractor50.7002.821CENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold
32 HIST2H2BEinteractor40.6677.417Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
33 HIST3H3interactor110.327198.123Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
34 HNRNPUinteractor120.136243.468CDC45 (PF02724, IPR003874): CDC45-like protein
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
SAP (PF02037, IPR003034, SM00513): SAP domain
SPRY (PF00622, IPR003877, SM00449): SPRY domain
AAA_33 (PF13671): AAA domain
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
35 INCENPinteractor21.0000ATP-synt_E (PF05680, IPR008386): ATP synthase E chain
Ctr (PF04145, IPR007274): Ctr copper transporter family
DUF572 (PF04502, IPR007590): Family of unknown function (DUF572)
DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913)
INCENP_ARK-bind (PF03941, IPR005635): Inner centromere protein, ARK binding region
INCENP_N (PF12178, IPR022006): Chromosome passenger complex (CPC) protein INCENP N terminal
DUF3807 (PF12720, IPR024526): Protein of unknown function (DUF3807)
PRKCSH-like (PF12999, IPR028146): Glucosidase II beta subunit-like
36 LSM14Binteractor100FDF (PF09532, IPR019050, SM01199): FDF domain
LSM14 (PF12701, IPR025609): Scd6-like Sm domain
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
37 MAGEA10interactor100MAGE (PF01454, IPR002190): MAGE family
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
MAGE_N (PF12440, IPR021072): Melanoma associated antigen family N terminal
38 MAGIXinteractor100.778203.479PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
39 MAML1interactor31.0000MamL-1 (PF09596, IPR019082): MamL-1 domain
Kri1 (PF05178, IPR018034): KRI1-like family
PRIMA1 (PF16101): Proline-rich membrane anchor 1
40 MB21D1interactor100Mab-21 (PF03281, IPR024810): Mab-21 protein
41 MKRN3oncoprotein200zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
MKRN1_C (PF15815, IPR031644): E3 ubiquitin-protein ligase makorin-1, C-terminal
Torus (PF16131, IPR032297): Torus domain
zf-3CxxC_2 (PF17180): Zinc-binding domain
42 MRPS15interactor21.0000Ribosomal_S15 (PF00312, IPR000589): Ribosomal protein S15
43 MRPS27interactor21.0000MRP-S27 (PF10037, IPR019266): Mitochondrial 28S ribosomal protein S27
44 MRPS35interactor21.0000MRP-S28 (PF10213, IPR019349): Mitochondrial ribosomal subunit protein
45 MSH2suppressor70.53327.118MutS_I (PF01624, IPR007695): MutS domain I
MutS_II (PF05188, IPR007860): MutS domain II
MutS_V (PF00488, IPR000432, SM00534): MutS domain V
MutS_III (PF05192, IPR007696, SM00533): MutS domain III
AAA_27 (PF13514): AAA domain
46 MUS81suppressor70.38171.842ERCC4 (PF02732, IPR006166, SM00891): ERCC4 domain
MutL (PF13941, IPR006230): MutL protein
HHH_8 (PF14716, IPR010996): Helix-hairpin-helix domain
47 NIP7interactor40.6672.571UPF0113 (PF03657, IPR005155): Uncharacterised protein family (UPF0113)
48 NOL8interactor21.0000RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
TMPIT (PF07851, IPR012926): TMPIT-like protein
DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915)
49 NOTCH1suppressor120.41844.329Ank (PF00023, IPR002110, SM00248): Ankyrin repeat
EGF (PF00008, IPR000742, SM00181): EGF-like domain
EGF_2 (PF07974, IPR013111): EGF-like domain
EGF_alliinase (PF04863, IPR006947): Alliinase EGF-like domain
EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain
NOD (PF06816, IPR010660): NOTCH protein
NODP (PF07684, IPR011656): NOTCH protein
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
Notch (PF00066, IPR000800, SM00004): LNR domain
DUF3454 (PF11936, IPR024600): Domain of unknown function (DUF3454)
hEGF (PF12661, IPR013032): Human growth factor-like EGF
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
50 PI4K2Ainteractor21.0000Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
Ribosomal_S15 (PF00312, IPR000589): Ribosomal protein S15
PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
51 PLEConcoprotein204.925CDC37_N (PF03234, IPR013855, SM01071): Cdc37 N terminal kinase binding
CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
FUSC (PF04632, IPR006726): Fusaric acid resistance protein family
RNA_pol_Rbc25 (PF08292, IPR013238): RNA polymerase III subunit Rpc25
S10_plectin (PF03501, IPR005326): Plectin/S10 domain
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
DUF2229 (PF09989, IPR018709): CoA enzyme activase uncharacterised domain (DUF2229)
Plectin (PF00681, IPR001101, SM00250): Plectin repeat
YlqD (PF11068, IPR021297): YlqD protein
Alanine_zipper (PF11839, IPR021793): Alanine-zipper, major outer membrane lipoprotein
DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391)
DUF4140 (PF13600, IPR025554): N-terminal domain of unknown function (DUF4140)
52 POLR2Aprotein found in more fusions110.289432.270RNA_pol_Rpb1_1 (PF04997, IPR007080): RNA polymerase Rpb1, domain 1
RNA_pol_Rpb1_2 (PF00623, IPR000722): RNA polymerase Rpb1, domain 2
RNA_pol_Rpb1_3 (PF04983, IPR007066): RNA polymerase Rpb1, domain 3
RNA_pol_Rpb1_4 (PF05000, IPR007083): RNA polymerase Rpb1, domain 4
RNA_pol_Rpb1_5 (PF04998, IPR007081): RNA polymerase Rpb1, domain 5
RNA_pol_Rpb1_R (PF05001, IPR000684): RNA polymerase Rpb1 C-terminal repeat
53 POLR2Cinteractor50.50045.902RNA_pol_A_bac (PF01000, IPR011262): RNA polymerase Rpb3/RpoA insert domain
54 RARAoncoprotein40.6670.833zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
55 RBPJinteractor70.42945.440BTD (PF09270, IPR015350): Beta-trefoil DNA-binding domain
LAG1-DNAbind (PF09271, IPR015351): LAG1, DNA binding
TIG (PF01833, IPR002909): IPT/TIG domain
56 RCC2oncoprotein100RCC1 (PF00415, IPR000408): Regulator of chromosome condensation (RCC1) repeat
RCC1_2 (PF13540): Regulator of chromosome condensation (RCC1) repeat
57 RIF1interactor30.3335.825Rif1_N (PF12231, IPR022031): Rap1-interacting factor 1 N terminal
DUF4519 (PF15012, IPR027960): Domain of unknown function (DUF4519)
NICE-1 (PF15845, IPR031698): Cysteine-rich C-terminal 1 family
58 RPAP1interactor30.6671.643ATP-synt_B (PF00430, IPR002146): ATP synthase B/B' CF(0)
RPAP1_C (PF08620, IPR013929): RPAP1-like, C-terminal
RPAP1_N (PF08621, IPR013930): RPAP1-like, N-terminal
59 SLX1Ainteractor40.8330.333GIY-YIG (PF01541, IPR000305, SM00465): GIY-YIG catalytic domain
FANCL_C (PF11793, IPR026850): FANCL C-terminal domain
60 SLX1Binteractor60.53347.049GIY-YIG (PF01541, IPR000305, SM00465): GIY-YIG catalytic domain
FANCL_C (PF11793, IPR026850): FANCL C-terminal domain
61 SLX4suppressor110.382134.181BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Slx4 (PF09494, IPR018574): Slx4 endonuclease
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
62 SLX4IPinteractor50.8009.909UPF0492 (PF15744, IPR031479): Uncharacterized protein family UPF0492
63 SUMO2interactor90.286285.550Rad60-SLD (PF11976, IPR022617): Ubiquitin-2 like Rad60 SUMO-like
64 TAF1oncoprotein80.50095.942Exonuc_VII_L (PF02601, IPR020579): Exonuclease VII, large subunit
LcrG (PF07216, IPR009863): LcrG protein
Opi1 (PF08618, IPR013927): Transcription factor Opi1
Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region
PRP1_N (PF06424, IPR010491): PRP1 splicing factor, N-terminal
TBP-binding (PF09247, IPR009067): TATA box-binding protein binding
U3_snoRNA_assoc (PF08297, IPR013268): U3 snoRNA associated
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
DUF3591 (PF12157, IPR022591): Protein of unknown function (DUF3591)
zf-CCHC_6 (PF15288): Zinc knuckle
65 TAF10interactor80.67927.570TFIID_30kDa (PF03540, IPR003923): Transcription initiation factor TFIID 23-30kDa subunit
66 TAF12interactor50.9007.874TFIID_20kDa (PF03847, IPR003228): Transcription initiation factor TFIID subunit A
67 TAF6interactor100.422103.815CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
TAF6_C (PF07571, IPR011442): TAF6 C-terminal HEAT repeat domain
Spo0A_C (PF08769, IPR014879): Sporulation initiation factor Spo0A C terminal
TAF (PF02969, IPR004823, SM00803): TATA box binding protein associated factor (TAF)
68 TAF7interactor70.66743.177DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
ELM2 (PF01448, IPR000949): ELM2 domain
TAFII55_N (PF04658, IPR006751): TAFII55 protein conserved region
XhlA (PF10779, IPR019715): Haemolysin XhlA
Noelin-1 (PF12308, IPR022082): Neurogenesis glycoprotein
69 TBPinteractor100.52861.889TBP (PF00352, IPR000814): Transcription factor TFIID (or TATA-binding protein, TBP)
EPL1 (PF10513, IPR019542): Enhancer of polycomb-like
Med3 (PF11593, IPR020998): Mediator complex subunit 3 fungal
70 THAP11interactor50.33371.702THAP (PF05485, IPR006612, SM00980): THAP domain
DUF2722 (PF10846, IPR021216): Protein of unknown function (DUF2722)
MRP-S31 (PF15433, IPR026299): Mitochondrial 28S ribosomal protein S31
FAM76 (PF16046, IPR032017): FAM76 protein
71 TOPBP1protein found in more fusions40.6671.750BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
PTCB-BRCT (PF12738, IPR001357): twin BRCT domain
RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain
72 TRIM26interactor31.0000Nop14 (PF04147, IPR007276): Nop14-like family
SPRY (PF00622, IPR003877, SM00449): SPRY domain
IFT57 (PF10498, IPR019530): Intra-flagellar transport protein 57
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
PRY (PF13765, IPR006574, SM00589): SPRY-associated domain
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
73 TRIP12interactor100Alpha_GJ (PF03229, IPR004913): Alphavirus glycoprotein J
Ndc1_Nup (PF09531, IPR019049): Nucleoporin protein Ndc1-Nup
WWE (PF02825, IPR004170, SM00678): WWE domain
SOG2 (PF10428, IPR019487): RAM signalling pathway protein
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
UNC45-central (PF11701, IPR024660): Myosin-binding striated muscle assembly central
HEAT_2 (PF13646): HEAT repeats
74 TRMT2Binteractor100tRNA_U5-meth_tr (PF05958, IPR010280): tRNA (Uracil-5-)-methyltransferase
75 TWF2interactor21.0000Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein
76 UBL7oncoprotein21.0000UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
77 UHRF1interactor70.200110.998PHD (PF00628, IPR019787, SM00249): PHD-finger
SAD_SRA (PF02182, IPR003105, SM00466): SAD/SRA domain
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
TTD (PF12148, IPR021991): Tandem tudor domain within UHRF1
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
zf-RING_10 (PF16685, IPR032043): zinc RING finger of MSL2
78 UPF3Ainteractor21.0000Smg4_UPF3 (PF03467, IPR005120): Smg-4/UPF3 family
DDRGK (PF09756, IPR019153, SM01128): DDRGK domain
79 USHBP1interactor40.6671.648DASH_Dam1 (PF08653, IPR013962): DASH complex subunit Dam1
HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
SlyX (PF04102, IPR007236): SlyX
MCC-bdg_PDZ (PF10506, IPR019536): PDZ domain of MCC-2 bdg protein for Usher syndrome
YlqD (PF11068, IPR021297): YlqD protein
DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404)
CAGE1 (PF15066, IPR029381): Cancer-associated gene protein 1 family
TEX13 (PF15186, IPR028193): Testis-expressed sequence 13 protein family
80 USP45interactor31.0000HNH (PF01844, IPR002711): HNH endonuclease
UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein
LELP1 (PF15042, IPR026076): Late cornified envelope-like proline-rich protein 1
81 VPS37Binteractor100Mod_r (PF07200, IPR009851): Modifier of rudimentary (Mod(r)) protein
82 WDR5interactor60.53316.165WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
83 XPAoncoprotein60.60023.913XPA_C (PF05181, IPR022656): XPA protein C-terminus
XPA_N (PF01286, IPR022652): XPA protein N-terminal
MscS_TM (PF12794, IPR025692): Mechanosensitive ion channel inner membrane domain 1
zinc_ribbon_2 (PF13240, IPR026870): zinc-ribbon domain
84 XPConcoprotein40.33373.472Rad4 (PF03835, IPR018325): Rad4 transglutaminase-like domain
BHD_1 (PF10403, IPR018326, SM01030): Rad4 beta-hairpin domain 1
BHD_2 (PF10404, IPR018327, SM01031): Rad4 beta-hairpin domain 2
BHD_3 (PF10405, IPR018328, SM01032): Rad4 beta-hairpin domain 3
Macoilin (PF09726, IPR019130): Transmembrane protein
SOG2 (PF10428, IPR019487): RAM signalling pathway protein
Abdominal-A (PF12407, IPR022132): Homeobox protein
DUF4820 (PF16091, IPR032150): Domain of unknown function (DUF4820)
85 ZNF711interactor21.0000PyrI_C (PF02748, IPR020542): Aspartate carbamoyltransferase regulatory chain, metal binding domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
Zfx_Zfy_act (PF04704, IPR006794): Zfx / Zfy transcription activation region
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain
zf-C2H2_7 (PF15269): Zinc-finger

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