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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)91
The number (and %) of the onco-proteins32 (35.16 %)
The number (and %) of the tumor suppressors17 (18.68 %)
Total number of binary PPIs (saturation %)544 (13.28 %)
The number (and %) of affected PPIs90 (16.54 %)
The number of possible different fusions24
PPI diameter5
PPI radius3
The average degree of PPI10.967
Assortativity coefficient-0.3476
The network average Clustering coefficient0.524
The number (and %) of a zero Clustering coefficients6 (6.59 %)
The number (and %) of a zero Betweenness Centrality15 (16.48 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: LRRC28,TAB2 All fusions
Proteins found in more fusions TAB2 (see 1 fusions); TRAF6 (see 1 fusions); APP (see 5 fusions); TNF (see 1 fusions); HSP90AA1 (see 6 fusions); NPM1 (see 1 fusions); BECN1 (see 1 fusions); NFKB1 (see 2 fusions); MAPK14 (see 1 fusions); MALT1 (see 1 fusions); RIPK1 (see 1 fusions); YWHAZ (see 5 fusions); MCM2 (see 1 fusions); NLK (see 4 fusions); MAP3K7 (see 7 fusions); HDAC5 (see 1 fusions); IKBKB (see 2 fusions); UBC (see 7 fusions); TGM2 (see 3 fusions); ZBTB16 (see 4 fusions); TBL1X (see 2 fusions); VIM (see 1 fusions); HSPA8/HSPD1 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 LRRC28parental protein70.143187.334LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
2 TAB2parental protein830.1083908.623CUE (PF02845, IPR003892, SM00546): CUE domain
DivIC (PF04977, IPR007060): Septum formation initiator
Mnd1 (PF03962, IPR005647): Mnd1 family
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
3 APPprotein found in more fusions190.242119.092APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding
Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP)
BUD22 (PF09073, IPR015158): BUD22
IncA (PF04156, IPR007285): IncA protein
Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus
APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
4 ARoncoprotein130.47020.036Androgen_recep (PF02166, IPR001103): Androgen receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
5 ARRB2interactor140.31989.952Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain
Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain
6 ATG13oncoprotein40.6670.700ATG13 (PF10033, IPR018731): Autophagy-related protein 13
7 ATG5interactor30.6670.250APG5 (PF04106, IPR007239): Autophagy protein Apg5
8 BECN1suppressor80.4764.096APG6 (PF04111, IPR007243): Autophagy protein Apg6
Ima1_N (PF09779, IPR018617): Ima1 N-terminal domain
BH3 (PF15285, IPR029318): Beclin-1 BH3 domain, Bcl-2-interacting
9 BNIP3P6interactor100NA
10 BST2oncoprotein31.0000DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
DUF4472 (PF14739, IPR029329): Domain of unknown function (DUF4472)
BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2
11 CARD8oncoprotein50.7001.452CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain
FIIND (PF13553, IPR025307): Function to find
12 CARNMT1interactor40.6670.571N2227 (PF07942, IPR012901): N2227-like protein
RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
13 CCT7interactor100.20069.511Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
14 CHUKsuppressor210.44252.611Pkinase (PF00069, IPR000719): Protein kinase domain
IKKbetaNEMObind (PF12179, IPR022007): I-kappa-kinase-beta NEMO binding domain
15 CNTROBinteractor31.0000DUF724 (PF05266, IPR007930): Protein of unknown function (DUF724)
FadA (PF09403, IPR018543): Adhesion protein FadA
Flavodoxin_5 (PF12724, IPR026816): Flavodoxin domain
DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404)
DUF4472 (PF14739, IPR029329): Domain of unknown function (DUF4472)
16 CSinteractor31.0000Citrate_synt (PF00285, IPR002020): Citrate synthase, C-terminal domain
17 CST9Linteractor100Cystatin (PF00031, IPR000010, SM00043): Cystatin domain
18 DBN1oncoprotein50.6000.922Pinin_SDK_memA (PF04696, IPR006786): pinin/SDK/memA/ protein conserved region
Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein
CAF-1_p150 (PF11600): Chromatin assembly factor 1 complex p150 subunit, N-terminal
MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
19 EDARADDinteractor60.8000.500Death (PF00531, IPR000488, SM00005): Death domain
SCO1-SenC (PF02630, IPR003782): SCO1/SenC
20 ERBB4suppressor50.5002.665Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
DUF3951 (PF13131, IPR025028): Protein of unknown function (DUF3951)
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
21 ESR1suppressor240.300139.771Oest_recep (PF02159, IPR001292): Oestrogen receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal
22 F2Rinteractor31.00007tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
DUF412 (PF04217, IPR007334): Protein of unknown function, DUF412
23 FN1oncoprotein160.40874.258fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain
fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
24 FOSL1oncoprotein21.0000bZIP_1 (PF00170, IPR004827): bZIP transcription factor
25 GTF2Iinteractor50.6001.267GTF2I (PF02946, IPR004212): GTF2I-like repeat
26 HDAC1suppressor210.268129.840FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide
Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
27 HDAC3suppressor190.288103.893Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
28 HDAC5protein found in more fusions240.328140.287Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
NOA36 (PF06524, IPR010531): NOA36 protein
Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3
HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
29 HSP90AA1oncoprotein290.262297.302HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
30 HSP90AB4Pinteractor100DUF11 (PF01345, IPR001434): Domain of unknown function DUF11
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase (PF00069, IPR000719): Protein kinase domain
PPAK (PF02818, IPR004168): PPAK motif
Titin_Z (PF09042, IPR015129): Titin Z
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Y_Y_Y (PF07495, IPR011123): Y_Y_Y domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
Ig_3 (PF13927): Immunoglobulin domain
31 HSPA1Binteractor60.26723.835HSP70 (PF00012, IPR013126): Hsp70 protein
32 HSPA1Linteractor120.364155.161HSP70 (PF00012, IPR013126): Hsp70 protein
33 HSPA6interactor70.57115.749HSP70 (PF00012, IPR013126): Hsp70 protein
34 HSPA8oncoprotein150.257107.536HSP70 (PF00012, IPR013126): Hsp70 protein
35 HSPD1suppressor100.35662.514Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
36 IKBKBprotein found in more fusions150.60415.134FliT (PF05400, IPR008622): Flagellar protein FliT
Glyco_hydro_65m (PF03632, IPR005195): Glycosyl hydrolase family 65 central catalytic domain
Pkinase (PF00069, IPR000719): Protein kinase domain
SlyX (PF04102, IPR007236): SlyX
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
IKKbetaNEMObind (PF12179, IPR022007): I-kappa-kinase-beta NEMO binding domain
37 IKBKGinteractor230.42964.464CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
DUF725 (PF05267, IPR007931): Protein of unknown function (DUF725)
NEMO (PF11577, IPR021063): NF-kappa-B essential modulator NEMO
LLC1 (PF14945, IPR020339): Normal lung function maintenance, Low in Lung Cancer 1 protein
CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator
38 IRAK1interactor130.45538.380Death (PF00531, IPR000488, SM00005): Death domain
Pkinase (PF00069, IPR000719): Protein kinase domain
39 LITAFsuppressor100zf-LITAF-like (PF10601, IPR006629, SM00714): LITAF-like zinc ribbon domain
DUF3824 (PF12868, IPR024436): Domain of unknwon function (DUF3824)
40 MALT1oncoprotein80.7621.121Peptidase_C14 (PF00656, IPR011600): Caspase domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
41 MAP3K7oncoprotein380.218418.038Mnd1 (PF03962, IPR005647): Mnd1 family
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
42 MAP3K8suppressor80.6792.373Pkinase (PF00069, IPR000719): Protein kinase domain
IML1 (PF12257, IPR027244): Vacuolar membrane-associated protein Iml1
43 MAPK14oncoprotein110.35631.097Pkinase (PF00069, IPR000719): Protein kinase domain
44 MBD3interactor51.0000DUF2201_N (PF13203, IPR025154): Putative metallopeptidase domain
45 MCM2oncoprotein200.398110.381AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA)
MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
46 NCOR1oncoprotein150.44835.287BES1_N (PF05687, IPR008540): BES1/BZR1 plant transcription factor, N-terminal
Lamp (PF01299, IPR002000): Lysosome-associated membrane glycoprotein (Lamp)
MAS20 (PF02064, IPR002056): MAS20 protein import receptor
Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
Eapp_C (PF10238, IPR019370): E2F-associated phosphoprotein
Hid1 (PF12722): High-temperature-induced dauer-formation protein
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915)
GPS2_interact (PF15784, IPR031557): G-protein pathway suppressor 2-interacting domain
DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834)
RBR (PF17208): RNA binding Region
47 NFKB1suppressor120.41821.567Death (PF00531, IPR000488, SM00005): Death domain
GHMP_kinases_C (PF08544, IPR013750): GHMP kinases C terminal
RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
48 NLKprotein found in more fusions31.0000Pkinase (PF00069, IPR000719): Protein kinase domain
SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
49 NPM1suppressor140.56410.318Nucleoplasmin (PF03066): Nucleoplasmin/nucleophosmin domain
SDA1 (PF05285, IPR007949): SDA1
NPM1-C (PF16276, IPR032569): Nucleophosmin C-terminal domain
50 NR2C2suppressor110.48911.507Flagellin_N (PF00669, IPR001029): Bacterial flagellin N-terminal helical region
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
51 NUMBLinteractor40.6670.297DUF1932 (PF09130, IPR015814): Domain of unknown function (DUF1932)
NumbF (PF06311, IPR010449): NUMB domain
PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID)
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
DUF2722 (PF10846, IPR021216): Protein of unknown function (DUF2722)
SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
52 PDLIM7interactor60.6001.782LIM (PF00412, IPR001781, SM00132): LIM domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
zinc_ribbon_10 (PF10058, IPR019273): Predicted integral membrane zinc-ribbon metal-binding protein
DUF4749 (PF15936, IPR031847): Domain of unknown function (DUF4749)
53 PIAS3oncoprotein40.6671.167SAP (PF02037, IPR003034, SM00513): SAP domain
zf-MIZ (PF02891, IPR004181): MIZ/SP-RING zinc finger
PINIT (PF14324, IPR023321): PINIT domain
54 PPP2CBsuppressor50.5006.245Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
55 PPP6Cinteractor31.0000Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
56 RBCK1interactor140.53815.867GAGA (PF09237, IPR015318): GAGA factor
IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
57 RFPL4Binteractor40.6671.286SPRY (PF00622, IPR003877, SM00449): SPRY domain
PRY (PF13765, IPR006574, SM00589): SPRY-associated domain
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
58 RIPK1protein found in more fusions170.50028.865Death (PF00531, IPR000488, SM00005): Death domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
RHIM (PF12721, IPR025735): RIP homotypic interaction motif
59 RIPK2interactor120.7453.716CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
60 RNF4interactor90.5365.866Sgf11 (PF08209, IPR013246): Sgf11 (transcriptional regulation protein)
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
zf-UDP (PF14569, IPR027934): Zinc-binding RING-finger
61 SIK1suppressor50.8000.686Pkinase (PF00069, IPR000719): Protein kinase domain
62 SIK3oncoprotein40.6670.686GET2 (PF08690, IPR028143): GET complex subunit GET2
Pkinase (PF00069, IPR000719): Protein kinase domain
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
63 SIN3Aoncoprotein100.6229.527Sin3_corepress (PF08295, IPR013194, SM00761): Sin3 family co-repressor
PAH (PF02671, IPR003822, SM00309): Paired amphipathic helix repeat
Sin3a_C (PF16879, IPR031693): C-terminal domain of Sin3a protein
64 SLC19A3interactor100Folate_carrier (PF01770, IPR002666): Reduced folate carrier
NfeD (PF01957, IPR002810): NfeD-like C-terminal, partner-binding
65 SMAD7interactor90.5009.330MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
66 TAB1interactor300.225274.564PP2C (PF00481, IPR001932): Protein phosphatase 2C
67 TAB3oncoprotein180.36854.451CUE (PF02845, IPR003892, SM00546): CUE domain
Tmemb_cc2 (PF10267, IPR019394): Predicted transmembrane and coiled-coil 2 protein
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
68 TANKsuppressor70.8001.467DUF3713 (PF12506, IPR022186): Protein of unknown function (DUF3713)
TBD (PF12845, IPR024581): TBD domain
69 TBL1Xprotein found in more fusions90.7861.621K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
LisH (PF08513, IPR013720, SM00667): LisH
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
LCE6A (PF15858, IPR031716): Late cornified envelope protein 6A family
70 TBL1XR1oncoprotein100.7562.798LisH (PF08513, IPR013720, SM00667): LisH
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
71 TGFBR1oncoprotein60.6002.602Activin_recp (PF01064, IPR000472): Activin types I and II receptor domain
Pkinase (PF00069, IPR000719): Protein kinase domain
TGF_beta_GS (PF08515, IPR003605, SM00467): Transforming growth factor beta type I GS-motif
72 TGM2protein found in more fusions80.66717.069Transglut_C (PF00927, IPR008958): Transglutaminase family, C-terminal ig like domain
Transglut_N (PF00868, IPR001102): Transglutaminase family
Transglut_core (PF01841, IPR002931, SM00460): Transglutaminase-like superfamily
73 TIRAPinteractor70.7331.127TIR_2 (PF13676, IPR000157): TIR domain
74 TLR3interactor40.8330.154LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
LRRCT (PF01463, IPR000483, SM00082): Leucine rich repeat C-terminal domain
LRRNT (PF01462, IPR000372, SM00013): Leucine rich repeat N-terminal domain
TIR (PF01582, IPR000157, SM00255): TIR domain
LRR_5 (PF13306, IPR026906): Leucine rich repeats (6 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
75 TNFoncoprotein110.7782.267TNF (PF00229, IPR006052, SM00207): TNF(Tumour Necrosis Factor) family
76 TNFRSF11Aoncoprotein41.0000Abi (PF02517, IPR003675): CAAX protease self-immunity
DAG1 (PF05454, IPR008465): Dystroglycan (Dystrophin-associated glycoprotein 1)
KIX (PF02172, IPR003101): KIX domain
TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region
77 TRAF2interactor220.38688.978MATH (PF00917, IPR002083, SM00061): MATH domain
Sina (PF03145, IPR018121): Seven in absentia protein family
SlyX (PF04102, IPR007236): SlyX
zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger
TRAF_BIRC3_bd (PF16673, IPR032070): TNF receptor-associated factor BIRC3 binding domain
zf-C3HC4_5 (PF17121, IPR001841): Zinc finger, C3HC4 type (RING finger)
78 TRAF3IP1interactor70.52423.434MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
79 TRAF6protein found in more fusions340.227268.340SlyX (PF04102, IPR007236): SlyX
zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
80 TRIM22interactor200SPRY (PF00622, IPR003877, SM00449): SPRY domain
YojJ (PF10372, IPR019457): Bacterial membrane-spanning protein N-terminus
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
UBZ_FAAP20 (PF15750, IPR031490): Ubiquitin-binding zinc-finger
CREPT (PF16566, IPR032337): Cell-cycle alteration and expression-elevated protein in tumour
81 TRIM38interactor60.5007.222DUF342 (PF03961, IPR005646): Protein of unknown function (DUF342)
SPRY (PF00622, IPR003877, SM00449): SPRY domain
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
PRY (PF13765, IPR006574, SM00589): SPRY-associated domain
zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
82 TRIM5interactor70.7330.815Baculo_IE-1 (PF05290, IPR007954): Baculovirus immediate-early protein (IE-0)
Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus
SPRY (PF00622, IPR003877, SM00449): SPRY domain
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
83 UBCprotein found in more fusions230.281170.198ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
84 UBE2Iinteractor220.300103.036UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
85 USP18interactor70.7142.067TAFII55_N (PF04658, IPR006751): TAFII55 protein conserved region
UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
86 VIMsuppressor90.6073.703Filament (PF00038, IPR001664): Intermediate filament protein
Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region
87 WDR34interactor50.8000.393GTF2I (PF02946, IPR004212): GTF2I-like repeat
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
88 XIAPinteractor100.7502.363BIR (PF00653, IPR001370, SM00238): Inhibitor of Apoptosis domain
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
89 XPO1interactor320.218324.015CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
90 YWHAZprotein found in more fusions150.42955.52414-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
91 ZBTB16suppressor120.60013.073BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger

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