1 |
TUBB | parental protein | 217 | 0.107 | 18784.448 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
2 |
NFASC | interactor | 0 | 0 | 0 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Bravo_FIGEY (PF13882, IPR026966): Bravo-like intracellular region Ig_3 (PF13927): Immunoglobulin domain TMEM154 (PF15102, IPR028064): TMEM154 protein family |
3 |
ADRB2 | interactor | 22 | 0.271 | 60.893 | 7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family) |
4 |
AGO3 | interactor | 13 | 0.564 | 6.604 | ArgoL1 (PF08699, IPR014811, SM01163): Argonaute linker 1 domain PAZ (PF02170, IPR003100, SM00949): PAZ domain Piwi (PF02171, IPR003165, SM00950): Piwi domain ArgoN (PF16486, IPR032474): N-terminal domain of argonaute ArgoMid (PF16487, IPR032473): Mid domain of argonaute ArgoL2 (PF16488, IPR032472): Argonaute linker 2 domain |
5 |
AGO4 | interactor | 10 | 0.533 | 3.328 | ArgoL1 (PF08699, IPR014811, SM01163): Argonaute linker 1 domain PAZ (PF02170, IPR003100, SM00949): PAZ domain Piwi (PF02171, IPR003165, SM00950): Piwi domain ArgoN (PF16486, IPR032474): N-terminal domain of argonaute ArgoMid (PF16487, IPR032473): Mid domain of argonaute ArgoL2 (PF16488, IPR032472): Argonaute linker 2 domain |
6 |
AIRE | interactor | 15 | 0.396 | 10.640 | PHD (PF00628, IPR019787, SM00249): PHD-finger SAND (PF01342, IPR000770, SM00258): SAND domain HSR (PF03172, IPR004865): HSR domain zf-PHD-like (PF15446): PHD/FYVE-zinc-finger like domain |
7 |
AKT1 | oncoprotein | 30 | 0.367 | 80.009 | PH (PF00169, IPR001849, SM00233): PH domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
8 |
ALKBH3 | interactor | 8 | 0.500 | 1.985 | 2OG-FeII_Oxy_2 (PF13532, IPR027450): 2OG-Fe(II) oxygenase superfamily |
9 |
ANXA5 | oncoprotein | 11 | 0.418 | 9.126 | Annexin (PF00191, IPR018502, SM00335): Annexin |
10 |
AP2M1 | protein found in more fusions | 25 | 0.496 | 31.515 | Adap_comp_sub (PF00928, IPR008968): Adaptor complexes medium subunit family Clat_adaptor_s (PF01217, IPR022775): Clathrin adaptor complex small chain |
11 |
APP | protein found in more fusions | 57 | 0.179 | 582.390 | APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP) BUD22 (PF09073, IPR015158): BUD22 IncA (PF04156, IPR007285): IncA protein Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein |
12 |
ARL8B | interactor | 3 | 0.667 | 0.143 | Arf (PF00025, IPR006689, SM00177): ADP-ribosylation factor family |
13 |
ARMC6 | interactor | 8 | 0.536 | 1.848 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat Mis14 (PF08641, IPR013950): Kinetochore protein Mis14 like Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain |
14 |
ARRB1 | interactor | 22 | 0.429 | 34.942 | Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain |
15 |
ASB17 | interactor | 5 | 0.700 | 0.448 | HTH_Mga (PF08280, IPR013199): M protein trans-acting positive regulator (MGA) HTH domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) SOCS_box (PF07525, IPR001496): SOCS box |
16 |
ASNA1 | interactor | 7 | 0.524 | 3.459 | ArsA_ATPase (PF02374, IPR025723): Anion-transporting ATPase |
17 |
ATF2 | oncoprotein | 13 | 0.470 | 6.611 | bZIP_1 (PF00170, IPR004827): bZIP transcription factor zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type |
18 |
ATP5B | interactor | 28 | 0.410 | 63.385 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain NACHT (PF05729): NACHT domain |
19 |
ATXN3 | interactor | 10 | 0.556 | 2.470 | Josephin (PF02099, IPR006155): Josephin UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3 |
20 |
AURKA | oncoprotein | 31 | 0.414 | 56.950 | Pkinase (PF00069, IPR000719): Protein kinase domain MTBP_C (PF14920, IPR029418): MDM2-binding |
21 |
AURKB | interactor | 23 | 0.463 | 30.758 | Pkinase (PF00069, IPR000719): Protein kinase domain |
22 |
B4GALT1 | protein found in more fusions | 4 | 0.667 | 0.105 | Glyco_transf_7C (PF02709, IPR027791): N-terminal domain of galactosyltransferase Glyco_transf_7N (PF13733, IPR027995): N-terminal region of glycosyl transferase group 7 |
23 |
BRCA1 | suppressor | 25 | 0.351 | 62.056 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT |
24 |
BUB1B | oncoprotein | 12 | 0.473 | 9.064 | Mad3_BUB1_I (PF08311, IPR013212, SM00777): Mad3/BUB1 homology region 1 Mad3_BUB1_II (PF08171, IPR012572): Mad3/BUB1 homology region 2 Pkinase (PF00069, IPR000719): Protein kinase domain XhlA (PF10779, IPR019715): Haemolysin XhlA CCDC-167 (PF15188, IPR028194): Coiled-coil domain-containing protein 167 |
25 |
CAND1 | interactor | 43 | 0.501 | 71.281 | Adaptin_N (PF01602, IPR002553): Adaptin N terminal region DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981) HEAT (PF02985, IPR000357): HEAT repeat TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20) RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II |
26 |
CBL | suppressor | 30 | 0.406 | 78.171 | Cbl_N (PF02262, IPR003153): CBL proto-oncogene N-terminal domain 1 Cbl_N2 (PF02761, IPR014741): CBL proto-oncogene N-terminus, EF hand-like domain Cbl_N3 (PF02762, IPR014742): CBL proto-oncogene N-terminus, SH2-like domain UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain Prok-RING_4 (PF14447): Prokaryotic RING finger family 4 zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain |
27 |
CCT2 | interactor | 50 | 0.309 | 255.764 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
28 |
CCT8 | interactor | 40 | 0.276 | 166.684 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
29 |
CD4 | suppressor | 14 | 0.410 | 13.875 | ATP1G1_PLM_MAT8 (PF02038, IPR000272): ATP1G1/PLM/MAT8 family C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain CD4-extracel (PF09191, IPR015274): CD4, extracellular ig (PF00047, IPR013151, SM00409): Immunoglobulin domain Tcell_CD4_C (PF12104, IPR021963): T cell CD4 receptor C terminal region |
30 |
CD81 | interactor | 18 | 0.419 | 23.481 | Tetraspannin (PF00335, IPR018499): Tetraspanin family |
31 |
CDC20 | oncoprotein | 27 | 0.434 | 46.146 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
32 |
CDC37 | protein found in more fusions | 31 | 0.425 | 59.193 | CDC37_C (PF08564, IPR013873, SM01069): Cdc37 C terminal domain CDC37_M (PF08565, IPR013874, SM01070): Cdc37 Hsp90 binding domain CDC37_N (PF03234, IPR013855, SM01071): Cdc37 N terminal kinase binding Rho_Binding (PF08912, IPR015008): Rho Binding TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding |
33 |
CDC5L | interactor | 57 | 0.314 | 307.697 | OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain |
34 |
CDK13 | interactor | 10 | 0.667 | 1.531 | K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain Pkinase (PF00069, IPR000719): Protein kinase domain Macoilin (PF09726, IPR019130): Transmembrane protein THRAP3_BCLAF1 (PF15440, IPR029199): THRAP3/BCLAF1 family |
35 |
CDKN1A | suppressor | 26 | 0.446 | 35.090 | CDI (PF02234, IPR003175): Cyclin-dependent kinase inhibitor |
36 |
CDKN2A | suppressor | 23 | 0.553 | 15.547 | Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_5 (PF13857): Ankyrin repeats (many copies) |
37 |
CEP250 | interactor | 21 | 0.495 | 16.270 | ACCA (PF03255, IPR001095): Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DASH_Dam1 (PF08653, IPR013962): DASH complex subunit Dam1 DivIC (PF04977, IPR007060): Septum formation initiator DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) EHN (PF06441, IPR010497): Epoxide hydrolase N terminus ERM (PF00769, IPR011259): Ezrin/radixin/moesin family Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family IncA (PF04156, IPR007285): IncA protein Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain SlyX (PF04102, IPR007236): SlyX Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein Syntaxin-6_N (PF09177, IPR015260): Syntaxin 6, N-terminal TSC22 (PF01166, IPR000580): TSC-22/dip/bun family CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Endonuc_Holl (PF10107, IPR019287): Endonuclease related to archaeal Holliday junction resolvase DUF2570 (PF10828, IPR022538): Protein of unknown function (DUF2570) DGF-1_C (PF11040, IPR021053): Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus DUF2968 (PF11180, IPR021350): Protein of unknown function (DUF2968) DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450) DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404) DUF4472 (PF14739, IPR029329): Domain of unknown function (DUF4472) Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion KAsynt_C_assoc (PF16197, IPR032821): Ketoacyl-synthetase C-terminal extension HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1 |
38 |
CEP76 | interactor | 10 | 0.578 | 2.222 | Transglut_core (PF01841, IPR002931, SM00460): Transglutaminase-like superfamily CEP76-C2 (PF15627, IPR028926): CEP76 C2 domain |
39 |
CLIP1 | oncoprotein | 7 | 0.524 | 4.052 | ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) CAP_GLY (PF01302, IPR000938, SM01052): CAP-Gly domain CP12 (PF02672, IPR003823, SM01093): CP12 domain DASH_Hsk3 (PF08227, IPR013183): DASH complex subunit Hsk3 like DUF848 (PF05852, IPR008566): Gammaherpesvirus protein of unknown function (DUF848) FlaC_arch (PF05377, IPR008039): Flagella accessory protein C (FlaC) FliJ (PF02050, IPR012823): Flagellar FliJ protein Lectin_N (PF03954, IPR005640): Hepatic lectin, N-terminal domain SlyX (PF04102, IPR007236): SlyX ApoO (PF09769, IPR019166): Apolipoprotein O Ax_dynein_light (PF10211, IPR019347): Axonemal dynein light chain ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200) Leu_zip (PF15294): Leucine zipper CLIP1_ZNF (PF16641, IPR032108): CLIP1 zinc knuckle PKcGMP_CC (PF16808, IPR031831): Coiled-coil N-terminus of cGMP-dependent protein kinase |
40 |
CMTM5 | suppressor | 2 | 1.000 | 0 | MARVEL (PF01284, IPR008253): Membrane-associating domain DUF2207 (PF09972, IPR018702): Predicted membrane protein (DUF2207) |
41 |
CNN1 | suppressor | 2 | 1.000 | 0 | Calponin (PF00402, IPR000557): Calponin family repeat CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain |
42 |
COPB2 | interactor | 12 | 0.545 | 5.984 | Coatomer_WDAD (PF04053, IPR006692): Coatomer WD associated region WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat |
43 |
COPS5 | protein found in more fusions | 53 | 0.412 | 168.016 | JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease |
44 |
COPS6 | interactor | 30 | 0.571 | 34.759 | DUF320 (PF03777, IPR005528): Small secreted domain (DUF320) JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function |
45 |
CRK | oncoprotein | 24 | 0.533 | 26.489 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_2 (PF07653, IPR011511): Variant SH3 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
46 |
CRY1 | interactor | 20 | 0.363 | 22.289 | DNA_photolyase (PF00875, IPR006050): DNA photolyase FAD_binding_7 (PF03441, IPR005101): FAD binding domain of DNA photolyase |
47 |
CRYZ | interactor | 4 | 0.667 | 0.363 | ADH_N (PF08240, IPR013154): Alcohol dehydrogenase GroES-like domain ADH_zinc_N (PF00107, IPR013149): Zinc-binding dehydrogenase ADH_zinc_N_2 (PF13602): Zinc-binding dehydrogenase |
48 |
CUL1 | suppressor | 53 | 0.425 | 147.312 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
49 |
CUL2 | suppressor | 40 | 0.442 | 92.903 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
50 |
CUL3 | protein found in more fusions | 76 | 0.305 | 542.800 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal |
51 |
CUL4A | protein found in more fusions | 38 | 0.458 | 95.997 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
52 |
CUL4B | oncoprotein | 31 | 0.619 | 20.587 | Cullin (PF00888, IPR001373, SM00182): Cullin family EBP50_C (PF09007, IPR015098): EBP50, C-terminal Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain PG_binding_4 (PF12229, IPR022029): Putative peptidoglycan binding domain MDFI (PF15316, IPR026134): MyoD family inhibitor |
53 |
CUL5 | suppressor | 33 | 0.598 | 35.067 | Cullin (PF00888, IPR001373, SM00182): Cullin family GlutR_dimer (PF00745, IPR015896): Glutamyl-tRNAGlu reductase, dimerisation domain Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
54 |
DCUN1D1 | interactor | 27 | 0.641 | 20.975 | Cullin_binding (PF03556, IPR005176): Cullin binding UBA_4 (PF14555): UBA-like domain |
55 |
DFFA | suppressor | 8 | 0.679 | 2.046 | CIDE-N (PF02017, IPR003508): CIDE-N domain DFF-C (PF09033, IPR015121): DNA Fragmentation factor 45kDa, C terminal domain T2SSppdC (PF12528, IPR022204): Type II secretion prepilin peptidase dependent protein C SAPIS-gp6 (PF16722, IPR031999): Pathogenicity island protein gp6 in Staphylococcus |
56 |
DISC1 | interactor | 9 | 0.583 | 3.403 | HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper Mnd1 (PF03962, IPR005647): Mnd1 family TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein Tropomyosin (PF00261, IPR000533): Tropomyosin UVR (PF02151, IPR001943): UvrB/uvrC motif CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding |
57 |
EEF1A1 | suppressor | 76 | 0.240 | 696.817 | GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain |
58 |
EEF2 | interactor | 44 | 0.338 | 191.025 | EFG_C (PF00679, IPR000640, SM00838): Elongation factor G C-terminus EFG_IV (PF03764, IPR005517, SM00889): Elongation factor G, domain IV GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 EFG_II (PF14492, IPR009022): Elongation Factor G, domain II |
59 |
EGFR | oncoprotein | 67 | 0.255 | 621.521 | Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT) GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV |
60 |
EIF5 | interactor | 12 | 0.561 | 7.887 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal Hist_rich_Ca-bd (PF10529, IPR019552): Histidine-rich Calcium-binding repeat region eIF-5_eIF-2B (PF01873, IPR002735, SM00653): Domain found in IF2B/IF5 W2 (PF02020, IPR003307, SM00515): eIF4-gamma/eIF5/eIF2-epsilon |
61 |
ELAVL1 | oncoprotein | 55 | 0.184 | 551.045 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
62 |
EMD | interactor | 28 | 0.399 | 50.229 | LEM (PF03020, IPR003887, SM00540): LEM domain SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein |
63 |
EPRS | interactor | 26 | 0.332 | 55.390 | GST_C (PF00043, IPR004046): Glutathione S-transferase, C-terminal domain HGTP_anticodon (PF03129, IPR004154): Anticodon binding domain ProRS-C_1 (PF09180, IPR016061, SM00946): Prolyl-tRNA synthetase, C-terminal tRNA-synt_1c (PF00749, IPR020058): tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C (PF03950, IPR020059): tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_2b (PF00587, IPR002314): tRNA synthetase class II core domain (G, H, P, S and T) WHEP-TRS (PF00458, IPR000738, SM00991): WHEP-TRS domain |
64 |
EPS15 | oncoprotein | 17 | 0.517 | 13.993 | Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391) EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand EF-hand_7 (PF13499, IPR011992): EF-hand domain pair |
65 |
ERBB3 | oncoprotein | 23 | 0.411 | 39.919 | Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV |
66 |
ERG | oncoprotein | 10 | 0.578 | 2.788 | Ets (PF00178, IPR000418, SM00413): Ets-domain SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif) SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain |
67 |
ERLIN2 | interactor | 11 | 0.473 | 4.641 | Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family DUF4346 (PF14251, IPR025595): Domain of unknown function (DUF4346) |
68 |
ERRFI1 | suppressor | 18 | 0.529 | 9.427 | GTPase_binding (PF09027, IPR015116): GTPase binding Inhibitor_Mig-6 (PF11555, IPR021619): EGFR receptor inhibitor Mig-6 |
69 |
ESR1 | suppressor | 49 | 0.316 | 209.864 | Oest_recep (PF02159, IPR001292): Oestrogen receptor zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal |
70 |
ESRRB | suppressor | 17 | 0.610 | 9.618 | zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains) Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor |
71 |
FBXO6 | interactor | 46 | 0.297 | 167.743 | FBA (PF04300, IPR007397): F-box associated region F-box-like (PF12937, IPR001810): F-box-like |
72 |
FN1 | oncoprotein | 47 | 0.302 | 184.765 | fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) |
73 |
FNBP1 | oncoprotein | 4 | 0.667 | 0.087 | FCH (PF00611, IPR001060, SM00055): Fes/CIP4, and EFC/F-BAR homology domain HR1 (PF02185, IPR011072, SM00742): Hr1 repeat Laminin_II (PF06009, IPR010307): Laminin Domain II DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) SH3_9 (PF14604, IPR001452): Variant SH3 domain T3SSipB (PF16535, IPR032391): Type III cell invasion protein SipB |
74 |
FUS | suppressor | 49 | 0.409 | 150.357 | Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others Limkain-b1 (PF11608, IPR024582): Limkain b1 FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 Keratin_2_head (PF16208, IPR032444): Keratin type II head |
75 |
FYTTD1 | interactor | 3 | 1.000 | 0 | FYTT (PF07078, IPR009782): Forty-two-three protein |
76 |
GAN | protein found in more fusions | 13 | 0.621 | 2.048 | BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch BTB (PF00651, IPR013069, SM00225): BTB/POZ domain Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif Kelch_3 (PF13415): Galactose oxidase, central domain Kelch_5 (PF13854): Kelch motif |
77 |
GAPDH | oncoprotein | 60 | 0.306 | 389.094 | Gp_dh_C (PF02800, IPR020829): Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N (PF00044, IPR020828, SM00846): Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain OstA (PF03968, IPR005653): OstA-like protein |
78 |
GDAP1 | interactor | 2 | 1.000 | 0 | SyrA (PF11089, IPR024239): Exopolysaccharide production repressor GST_C_2 (PF13410): Glutathione S-transferase, C-terminal domain GST_N_3 (PF13417, IPR004045): Glutathione S-transferase, N-terminal domain DUF4296 (PF14129, IPR025381): Domain of unknown function (DUF4296) |
79 |
GRB2 | oncoprotein | 49 | 0.339 | 222.624 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain DUF5093 (PF17011, IPR031533): Domain of unknown function (DUF5093) |
80 |
HAUS1 | interactor | 12 | 0.564 | 4.439 | THP2 (PF09432, IPR018557): Tho complex subunit THP2 XhlA (PF10779, IPR019715): Haemolysin XhlA DUF3496 (PF12001, IPR021885): Domain of unknown function (DUF3496) |
81 |
HAUS2 | interactor | 9 | 0.694 | 1.364 | DpnII (PF04556, IPR007637): DpnII restriction endonuclease HAUS2 (PF15003, IPR028346): HAUS augmin-like complex subunit 2 |
82 |
HDAC5 | protein found in more fusions | 40 | 0.306 | 122.019 | Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain NOA36 (PF06524, IPR010531): NOA36 protein Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3 HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4 |
83 |
HDAC6 | oncoprotein | 32 | 0.333 | 93.441 | Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain PSGP (PF07276, IPR009900): Apopolysialoglycoprotein (PSGP) zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein |
84 |
HGS | interactor | 17 | 0.360 | 34.753 | FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif VHS (PF00790, IPR002014, SM00288): VHS domain EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region Hrs_helical (PF12210, IPR024641): Hepatocyte growth factor-regulated tyrosine kinase substrate PIEZO (PF15917, IPR031805): Piezo |
85 |
HSP90AA1 | oncoprotein | 95 | 0.250 | 1049.933 | HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein |
86 |
HSP90AB1 | oncoprotein | 83 | 0.253 | 710.587 | HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein |
87 |
HSPA1A | interactor | 76 | 0.213 | 794.869 | HSP70 (PF00012, IPR013126): Hsp70 protein |
88 |
HSPA4 | interactor | 43 | 0.306 | 203.989 | Herpes_ICP4_N (PF03584, IPR005206): Herpesvirus ICP4-like protein N-terminal region HSP70 (PF00012, IPR013126): Hsp70 protein TP53IP5 (PF15331, IPR029290): Cellular tumour antigen p53-inducible 5 |
89 |
HSPA8 | oncoprotein | 104 | 0.208 | 1470.919 | HSP70 (PF00012, IPR013126): Hsp70 protein |
90 |
HTRA2 | suppressor | 8 | 0.571 | 2.012 | Peptidase_S32 (PF05579, IPR008760): Equine arteritis virus serine endopeptidase S32 PDZ_2 (PF13180, IPR001478): PDZ domain Trypsin_2 (PF13365): Trypsin-like peptidase domain |
91 |
HTT | protein found in more fusions | 14 | 0.577 | 9.527 | HEAT (PF02985, IPR000357): HEAT repeat SPX (PF03105, IPR004331): SPX domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit DUF3652 (PF12372, IPR024613): Huntingtin protein region Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats |
92 |
HUWE1 | oncoprotein | 55 | 0.287 | 315.602 | BUD22 (PF09073, IPR015158): BUD22 DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908) DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913) FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM) Mucin (PF01456, IPR000458): Mucin-like glycoprotein Nop14 (PF04147, IPR007276): Nop14-like family PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32 RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain WWE (PF02825, IPR004170, SM00678): WWE domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54 U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414) |
93 |
ICAM1 | oncoprotein | 5 | 0.700 | 0.315 | Adhes-Ig_like (PF09085, IPR015169): Adhesion molecule, immunoglobulin-like C2-set_2 (PF08205, IPR013162): CD80-like C2-set immunoglobulin domain ICAM_N (PF03921, IPR013768): Intercellular adhesion molecule (ICAM), N-terminal domain Ig_2 (PF13895, IPR007110): Immunoglobulin domain Ig_3 (PF13927): Immunoglobulin domain |
94 |
ID2 | oncoprotein | 6 | 0.600 | 0.219 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain |
95 |
IFIT2 | interactor | 2 | 1.000 | 0 | TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat HTH_WhiA (PF02650, IPR023054): WhiA C-terminal HTH domain TPR_12 (PF13424): Tetratricopeptide repeat TPR_17 (PF13431): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat Mad3_BUB1_I_2 (PF17014, IPR031522): Putative Mad3/BUB1 like region 1 protein |
96 |
IGSF8 | oncoprotein | 11 | 0.582 | 3.995 | V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_2 (PF13895, IPR007110): Immunoglobulin domain Ig_3 (PF13927): Immunoglobulin domain |
97 |
INPPL1 | oncoprotein | 18 | 0.601 | 14.806 | Exo_endo_phos (PF03372, IPR005135): Endonuclease/Exonuclease/phosphatase family SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif) SH2 (PF00017, IPR000980, SM00252): SH2 domain |
98 |
IQCB1 | interactor | 22 | 0.381 | 31.365 | DUF1765 (PF08578, IPR013887): Protein of unknown function (DUF1765) IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif HJURP_C (PF12347, IPR022102): Holliday junction regulator protein family C-terminal repeat Condensin2nSMC (PF12422, IPR024741): Condensin II non structural maintenance of chromosomes subunit |
99 |
KAT2A | interactor | 7 | 0.667 | 0.654 | Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family PCAF_N (PF06466, IPR009464): PCAF (P300/CBP-associated factor) N-terminal domain Bromodomain (PF00439, IPR001487, SM00297): Bromodomain NICE-1 (PF15845, IPR031698): Cysteine-rich C-terminal 1 family |
100 |
KIAA0368 | interactor | 15 | 0.410 | 25.034 | HEAT (PF02985, IPR000357): HEAT repeat IFRD (PF05004, IPR007701): Interferon-related developmental regulator (IFRD) CLASP_N (PF12348, IPR024395): CLASP N terminal MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region Sec7_N (PF12783, IPR032691): Guanine nucleotide exchange factor in Golgi transport N-terminal Ecm29 (PF13001, IPR024372): Proteasome stabiliser HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats |
101 |
LAMP2 | protein found in more fusions | 10 | 0.389 | 4.388 | Lamp (PF01299, IPR002000): Lysosome-associated membrane glycoprotein (Lamp) |
102 |
LGALS2 | interactor | 3 | 0.667 | 0.182 | Gal-bind_lectin (PF00337, IPR001079, SM00908): Galactoside-binding lectin |
103 |
LGALS3BP | oncoprotein | 36 | 0.504 | 61.414 | BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch SRCR (PF00530, IPR001190): Scavenger receptor cysteine-rich domain SRCR_2 (PF15494, IPR017448): Scavenger receptor cysteine-rich domain |
104 |
LGR4 | interactor | 10 | 0.389 | 6.378 | 7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family) LRR_1 (PF00560, IPR001611): Leucine Rich Repeat LRRNT (PF01462, IPR000372, SM00013): Leucine rich repeat N-terminal domain LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_8 (PF13855, IPR001611): Leucine rich repeat |
105 |
LNX2 | interactor | 3 | 1.000 | 0 | PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) DZR (PF12773, IPR025874): Double zinc ribbon zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) |
106 |
LRRK2 | oncoprotein | 19 | 0.484 | 19.091 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain DUF1043 (PF06295, IPR009386): Protein of unknown function (DUF1043) T2SSE (PF00437, IPR001482): Type II/IV secretion system protein Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase Pkinase (PF00069, IPR000719): Protein kinase domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) PQQ_2 (PF13360, IPR002372): PQQ-like domain LRR_8 (PF13855, IPR001611): Leucine rich repeat COR (PF16095, IPR032171): C-terminal of Roc, COR, domain |
107 |
MAD2L1 | oncoprotein | 6 | 0.700 | 0.797 | HORMA (PF02301, IPR003511): HORMA domain |
108 |
MAGEA2B | interactor | 1 | 0 | 0 | MAGE (PF01454, IPR002190): MAGE family MAGE_N (PF12440, IPR021072): Melanoma associated antigen family N terminal |
109 |
MAGED2 | interactor | 21 | 0.567 | 17.797 | CDC27 (PF09507, IPR019038): DNA polymerase subunit Cdc27 MAGE (PF01454, IPR002190): MAGE family SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal DUF3306 (PF11748, IPR021735): Protein of unknown function (DUF3306) |
110 |
MAL2 | interactor | 2 | 1.000 | 0 | MARVEL (PF01284, IPR008253): Membrane-associating domain |
111 |
MAP1LC3A | interactor | 12 | 0.409 | 10.569 | Atg8 (PF02991, IPR004241): Autophagy protein Atg8 ubiquitin like |
112 |
MAPK7 | oncoprotein | 15 | 0.637 | 3.838 | Pkinase (PF00069, IPR000719): Protein kinase domain Rrn6 (PF10214, IPR019350): RNA polymerase I-specific transcription-initiation factor |
113 |
MAPRE1 | oncoprotein | 21 | 0.358 | 47.406 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain EB1 (PF03271, IPR004953): EB1-like C-terminal motif SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3 |
114 |
MARK4 | oncoprotein | 5 | 0.600 | 0.908 | KA1 (PF02149, IPR001772): Kinase associated domain 1 Pkinase (PF00069, IPR000719): Protein kinase domain UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain |
115 |
MAT2A | suppressor | 16 | 0.486 | 13.935 | S-AdoMet_synt_C (PF02773, IPR022630): S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M (PF02772, IPR022629): S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N (PF00438, IPR022628): S-adenosylmethionine synthetase, N-terminal domain |
116 |
MAT2B | interactor | 12 | 0.530 | 8.660 | RmlD_sub_bind (PF04321, IPR005913): RmlD substrate binding domain |
117 |
MCM2 | oncoprotein | 58 | 0.341 | 257.603 | AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA) MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2 MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain |
118 |
MCM5 | oncoprotein | 29 | 0.446 | 49.208 | MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain |
119 |
MDM2 | oncoprotein | 38 | 0.366 | 127.017 | Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region Presenilin (PF01080, IPR001108): Presenilin SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain zf-FPG_IleRS (PF06827, IPR010663): Zinc finger found in FPG and IleRS zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
120 |
MID1 | oncoprotein | 11 | 0.356 | 10.250 | Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain SPRY (PF00622, IPR003877, SM00449): SPRY domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING |
121 |
MID2 | interactor | 9 | 0.429 | 9.806 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain SPRY (PF00622, IPR003877, SM00449): SPRY domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger CEBP_ZZ (PF16366, IPR032296): Cytoplasmic polyadenylation element-binding protein ZZ domain APC_u15 (PF16636): Unstructured region on APC between APC_crr regions 5 and 6 |
122 |
MYC | oncoprotein | 37 | 0.325 | 120.485 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain Myc_N (PF01056, IPR012682): Myc amino-terminal region |
123 |
NANOG | interactor | 12 | 0.382 | 9.866 | Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
124 |
NCAM1 | interactor | 3 | 1.000 | 0 | fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain Syndecan (PF01034, IPR027789): Syndecan domain Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP) Ig_2 (PF13895, IPR007110): Immunoglobulin domain Ig_3 (PF13927): Immunoglobulin domain |
125 |
NCAPH2 | interactor | 5 | 0.833 | 0.057 | CNDH2_N (PF06278, IPR009378): Condensin II complex subunit CAP-H2 or CNDH2, N-terminal CNDH2_C (PF16858, IPR031737): Condensin II complex subunit CAP-H2 or CNDH2, C-term CNDH2_M (PF16869): PF16858 |
126 |
NEDD1 | interactor | 12 | 0.621 | 5.823 | NRBF2 (PF08961, IPR015056): Nuclear receptor-binding factor 2, autophagy regulator eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A FliM (PF02154, IPR001689): Flagellar motor switch protein FliM WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Mto2_bdg (PF12808, IPR024545): Micro-tubular organiser Mto1 C-term Mto2-binding region ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
127 |
NEDD8 | interactor | 31 | 0.540 | 53.061 | ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
128 |
NPHP1 | interactor | 4 | 0.667 | 0.500 | SH3_1 (PF00018, IPR001452, SM00326): SH3 domain FAM176 (PF14851): FAM176 family Speriolin_N (PF15058, IPR029385): Speriolin N terminus DUF4746 (PF15928, IPR031827): Domain of unknown function (DUF4746) |
129 |
NPHP4 | interactor | 7 | 0.524 | 5.635 | Corona_nucleoca (PF00937, IPR001218): Coronavirus nucleocapsid protein |
130 |
NTRK1 | oncoprotein | 93 | 0.222 | 1334.195 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain |
131 |
OLA1 | interactor | 12 | 0.485 | 8.002 | Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 (PF01926, IPR006073): 50S ribosome-binding GTPase YchF-GTPase_C (PF06071, IPR013029): Protein of unknown function (DUF933) |
132 |
PACRG | suppressor | 9 | 0.778 | 0.695 | ParcG (PF10274, IPR019399): Parkin co-regulated protein |
133 |
PAN2 | interactor | 23 | 0.332 | 29.106 | RNase_T (PF00929, IPR013520): Exonuclease UCH_1 (PF13423, IPR001394): Ubiquitin carboxyl-terminal hydrolase WD40_like (PF17005, IPR031544): WD40-like domain |
134 |
PARK2 | suppressor | 42 | 0.322 | 168.122 | IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
135 |
PARP1 | suppressor | 25 | 0.279 | 74.884 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain PADR1 (PF08063, IPR012982): PADR1 (NUC008) domain PARP (PF00644, IPR012317): Poly(ADP-ribose) polymerase catalytic domain PARP_reg (PF02877, IPR004102): Poly(ADP-ribose) polymerase, regulatory domain WGR (PF05406, IPR008893, SM00773): WGR domain zf-PARP (PF00645, IPR001510): Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region |
136 |
PDCD6IP | interactor | 14 | 0.449 | 14.151 | BRO1 (PF03097, IPR004328, SM01041): BRO1-like domain MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c ALIX_LYPXL_bnd (PF13949, IPR025304): ALIX V-shaped domain binding to HIV |
137 |
PEX14 | protein found in more fusions | 9 | 0.643 | 1.378 | HemX (PF04375, IPR007470): HemX, putative uroporphyrinogen-III C-methyltransferase Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated TolA_bind_tri (PF16331, IPR032519): TolA binding protein trimerisation |
138 |
PHB2 | interactor | 23 | 0.241 | 57.138 | DUF2605 (PF10792, IPR019728): Protein of unknown function (DUF2605) Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family |
139 |
PIK3R2 | oncoprotein | 23 | 0.526 | 26.432 | RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_9 (PF14604, IPR001452): Variant SH3 domain PI3K_P85_iSH2 (PF16454, IPR032498): Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain |
140 |
PINK1 | protein found in more fusions | 14 | 0.577 | 9.354 | Pkinase (PF00069, IPR000719): Protein kinase domain |
141 |
PKM | oncoprotein | 40 | 0.341 | 129.012 | PK (PF00224, IPR015793): Pyruvate kinase, barrel domain PK_C (PF02887, IPR015795): Pyruvate kinase, alpha/beta domain |
142 |
PKN1 | interactor | 10 | 0.583 | 4.257 | C2 (PF00168, IPR000008, SM00239): C2 domain HR1 (PF02185, IPR011072, SM00742): Hr1 repeat Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
143 |
POLH | oncoprotein | 8 | 0.536 | 4.434 | IMS (PF00817, IPR001126): impB/mucB/samB family IMS_HHH (PF11798, IPR024728): IMS family HHH motif IMS_C (PF11799, IPR017961): impB/mucB/samB family C-terminal domain PRP21_like_P (PF12230, IPR022030): Pre-mRNA splicing factor PRP21 like protein |
144 |
POLR2B | interactor | 14 | 0.549 | 5.613 | RNA_pol_Rpb2_1 (PF04563, IPR007644): RNA polymerase beta subunit RNA_pol_Rpb2_3 (PF04565, IPR007645): RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 (PF04566, IPR007646): RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 (PF04567, IPR007647): RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_6 (PF00562, IPR007120): RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_7 (PF04560, IPR007641): RNA polymerase Rpb2, domain 7 |
145 |
POU5F1 | oncoprotein | 22 | 0.367 | 40.240 | Pou (PF00157, IPR000327, SM00352): Pou domain - N-terminal to homeobox domain Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
146 |
PPID | interactor | 13 | 0.628 | 3.882 | Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 (PF13176, IPR019734): Tetratricopeptide repeat |
147 |
PPP1CC | oncoprotein | 22 | 0.455 | 21.142 | Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain |
148 |
PSMB2 | interactor | 13 | 0.333 | 15.358 | Proteasome (PF00227, IPR001353): Proteasome subunit |
149 |
PSMC2 | interactor | 25 | 0.370 | 66.077 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) |
150 |
PSMC5 | protein found in more fusions | 29 | 0.291 | 68.210 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) Laminin_II (PF06009, IPR010307): Laminin Domain II RILP (PF11461, IPR021563): Rab interacting lysosomal protein AAA_16 (PF13191): AAA ATPase domain |
151 |
PSTPIP1 | interactor | 3 | 0.667 | 0.100 | ABATE (PF07336, IPR010852): Putative stress-induced transcription regulator FCH (PF00611, IPR001060, SM00055): Fes/CIP4, and EFC/F-BAR homology domain WXG100 (PF06013, IPR010310): Proteins of 100 residues with WXG Golgin_A5 (PF09787, IPR019177): Golgin subfamily A member 5 |
152 |
PTEN | suppressor | 22 | 0.377 | 41.318 | DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain PTEN_C2 (PF10409, IPR014020): C2 domain of PTEN tumour-suppressor protein |
153 |
RAB8B | oncoprotein | 7 | 0.476 | 2.930 | Ras (PF00071, IPR001806, SM00173): Ras family |
154 |
RANBP2 | oncoprotein | 17 | 0.408 | 18.640 | Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat Ran_BP1 (PF00638, IPR000156, SM00160): RanBP1 domain zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others DUF2693 (PF10902, IPR024401): Protein of unknown function (DUF2693) IR1-M (PF12185, IPR022011): Nup358/RanBP2 E3 ligase domain Dmrt1 (PF12374, IPR022114): Double-sex mab3 related transcription factor 1 TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat TPR_11 (PF13414, IPR011990): TPR repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat |
155 |
RARS | interactor | 17 | 0.375 | 17.186 | Arg_tRNA_synt_N (PF03485, IPR005148, SM01016): Arginyl tRNA synthetase N terminal domain DALR_1 (PF05746, IPR008909, SM00836): DALR anticodon binding domain DivIC (PF04977, IPR007060): Septum formation initiator tRNA-synt_1d (PF00750, IPR015945): tRNA synthetases class I (R) Mto2_bdg (PF12808, IPR024545): Micro-tubular organiser Mto1 C-term Mto2-binding region |
156 |
RASSF1 | suppressor | 12 | 0.527 | 4.055 | RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) Nore1-SARAH (PF16517, IPR011524): Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain |
157 |
RNF146 | interactor | 6 | 0.400 | 1.969 | WWE (PF02825, IPR004170, SM00678): WWE domain zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
158 |
RPA1 | suppressor | 30 | 0.510 | 30.537 | Rep-A_N (PF04057, IPR007199): Replication factor-A protein 1, N-terminal domain Rep_fac-A_C (PF08646, IPR013955): Replication factor-A C terminal domain tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain REPA_OB_2 (PF16900, IPR031657): Replication protein A OB domain |
159 |
RPA2 | oncoprotein | 31 | 0.482 | 38.992 | RPA_C (PF08784, IPR014892): Replication protein A C terminal tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain RMI2 (PF16100, IPR032245): RecQ-mediated genome instability protein 2 |
160 |
RPA3 | interactor | 25 | 0.514 | 20.806 | Rep_fac-A_3 (PF08661, IPR013970): Replication factor A protein 3 |
161 |
RPGR | oncoprotein | 8 | 0.571 | 4.531 | PSK (PF06404, IPR009438): Phytosulfokine precursor protein (PSK) RCC1 (PF00415, IPR000408): Regulator of chromosome condensation (RCC1) repeat Kelch_4 (PF13418): Galactose oxidase, central domain RCC1_2 (PF13540): Regulator of chromosome condensation (RCC1) repeat |
162 |
RPS15A | interactor | 30 | 0.432 | 48.162 | Ribosomal_S8 (PF00410, IPR000630): Ribosomal protein S8 |
163 |
RPS6KB2 | interactor | 19 | 0.415 | 17.122 | Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain |
164 |
RUFY1 | interactor | 6 | 0.700 | 0.613 | DM (PF00751, IPR001275, SM00301): DM DNA binding domain FAA_hydrolase_N (PF09298, IPR015377): Fumarylacetoacetase N-terminal DUF641 (PF04859, IPR006943): Plant protein of unknown function (DUF641) DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger RUN (PF02759, IPR004012, SM00593): RUN domain Tektin (PF03148, IPR000435): Tektin family |
165 |
RUVBL1 | oncoprotein | 31 | 0.393 | 61.695 | TIP49 (PF06068, IPR010339): TIP49 C-terminus |
166 |
SCPEP1 | interactor | 5 | 0.700 | 0.790 | Peptidase_S10 (PF00450, IPR001563): Serine carboxypeptidase |
167 |
SDC3 | oncoprotein | 4 | 0.833 | 0.167 | Glycophorin_A (PF01102, IPR001195): Glycophorin A Syndecan (PF01034, IPR027789): Syndecan domain |
168 |
SF3B3 | interactor | 34 | 0.358 | 124.120 | CPSF_A (PF03178, IPR004871): CPSF A subunit region MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term |
169 |
SHC1 | oncoprotein | 30 | 0.502 | 38.519 | PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) SH2 (PF00017, IPR000980, SM00252): SH2 domain |
170 |
SKI | oncoprotein | 13 | 0.576 | 4.311 | c-SKI_SMAD_bind (PF08782, IPR014890, SM01046): c-SKI Smad4 binding domain Ski_Sno (PF02437, IPR003380): SKI/SNO/DAC family SlyX (PF04102, IPR007236): SlyX HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1 |
171 |
SMC3 | oncoprotein | 24 | 0.319 | 60.062 | SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain |
172 |
SMURF1 | interactor | 22 | 0.419 | 20.042 | C2 (PF00168, IPR000008, SM00239): C2 domain WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) |
173 |
SNCA | interactor | 22 | 0.495 | 27.994 | Synuclein (PF01387, IPR001058): Synuclein |
174 |
SNRNP200 | protein found in more fusions | 39 | 0.343 | 102.170 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase DUF603 (PF04645, IPR006739): Protein of unknown function, DUF603 Sec63 (PF02889, IPR004179, SM00973): Sec63 Brl domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
175 |
SNW1 | protein found in more fusions | 44 | 0.362 | 177.793 | SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term SIR4_SID (PF16991, IPR031556): Sir4 SID domain |
176 |
SORT1 | interactor | 5 | 0.600 | 0.359 | Sortilin_C (PF15901, IPR031777): Sortilin, neurotensin receptor 3, C-terminal Sortilin-Vps10 (PF15902, IPR031778): Sortilin, neurotensin receptor 3, |
177 |
SPP1 | oncoprotein | 5 | 0.700 | 0.527 | Osteopontin (PF00865, IPR002038, SM00017): Osteopontin |
178 |
STAU1 | protein found in more fusions | 34 | 0.400 | 70.009 | dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif Staufen_C (PF16482, IPR032478): Staufen C-terminal domain |
179 |
STK24 | interactor | 12 | 0.382 | 14.683 | DUF1241 (PF06840, IPR009652): Protein of unknown function (DUF1241) Pkinase (PF00069, IPR000719): Protein kinase domain |
180 |
SUMO2 | interactor | 14 | 0.436 | 10.116 | Rad60-SLD (PF11976, IPR022617): Ubiquitin-2 like Rad60 SUMO-like |
181 |
SYK | suppressor | 17 | 0.400 | 19.190 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain |
182 |
SYT9 | interactor | 1 | 0 | 0 | C2 (PF00168, IPR000008, SM00239): C2 domain |
183 |
TAOK2 | interactor | 3 | 1.000 | 0 | Band_3_cyto (PF07565, IPR013769): Band 3 cytoplasmic domain DUF342 (PF03961, IPR005646): Protein of unknown function (DUF342) Na_trans_assoc (PF06512, IPR010526): Sodium ion transport-associated Pkinase (PF00069, IPR000719): Protein kinase domain Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term |
184 |
TARDBP | interactor | 31 | 0.485 | 35.751 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
185 |
TBC1D3 | interactor | 2 | 1.000 | 0 | RabGAP-TBC (PF00566, IPR000195, SM00164): Rab-GTPase-TBC domain |
186 |
TINF2 | interactor | 7 | 0.533 | 1.207 | TINF2_N (PF14973, IPR029400): TERF1-interacting nuclear factor 2 N-terminus |
187 |
TJP1 | interactor | 9 | 0.500 | 5.053 | DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) SH3_2 (PF07653, IPR011511): Variant SH3 domain ZU5 (PF00791, IPR000906, SM00218): ZU5 domain Guanylate_kin (PF00625, IPR008145, SM00072): Guanylate kinase RPOL_N (PF14700, IPR029262): DNA-directed RNA polymerase N-terminal |
188 |
TNPO2 | interactor | 5 | 0.900 | 0.105 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat Dopey_N (PF04118, IPR007249): Dopey, N-terminal IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain DUF2573 (PF10835, IPR020393): Protein of unknown function (DUF2573) DUF3437 (PF11919, IPR021843): Domain of unknown function (DUF3437) MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats |
189 |
TP53 | suppressor | 56 | 0.319 | 282.412 | DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif |
190 |
TRAF3IP1 | interactor | 12 | 0.500 | 7.075 | MIP-T3 (PF10243): Microtubule-binding protein MIP-T3 |
191 |
TRIM29 | protein found in more fusions | 9 | 0.321 | 9.518 | MIS13 (PF08202, IPR013218): Mis12-Mtw1 protein family TP2 (PF01254, IPR000678): Nuclear transition protein 2 zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger |
192 |
TSGA10 | interactor | 4 | 1.000 | 0 | Bcr-Abl_Oligo (PF09036, IPR015123): Bcr-Abl oncoprotein oligomerisation domain SKA1 (PF07160, IPR009829): Spindle and kinetochore-associated protein 1 DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) Pox_A3L (PF05288, IPR007952): Poxvirus A3L Protein DUF4201 (PF13870, IPR025254): Domain of unknown function (DUF4201) PKcGMP_CC (PF16808, IPR031831): Coiled-coil N-terminus of cGMP-dependent protein kinase |
193 |
TUBA1A | oncoprotein | 86 | 0.155 | 1627.679 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
194 |
TUBA1B | protein found in more fusions | 51 | 0.159 | 480.119 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
195 |
TUBA1C | protein found in more fusions | 72 | 0.244 | 576.579 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
196 |
TUBA4A | interactor | 53 | 0.289 | 337.019 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
197 |
TUBA4B | interactor | 14 | 0.692 | 4.546 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain |
198 |
TUBB2A | interactor | 39 | 0.277 | 188.575 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
199 |
TUBB4B | interactor | 88 | 0.199 | 1115.621 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
200 |
TUBG1 | protein found in more fusions | 49 | 0.334 | 256.759 | Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain |
201 |
TUBGCP2 | interactor | 24 | 0.511 | 24.965 | Spc97_Spc98 (PF04130, IPR007259): Spc97 / Spc98 family zf-Tim10_DDP (PF02953, IPR004217): Tim10/DDP family zinc finger |
202 |
TUBGCP3 | interactor | 21 | 0.519 | 28.378 | Spc97_Spc98 (PF04130, IPR007259): Spc97 / Spc98 family |
203 |
TUBGCP4 | interactor | 15 | 0.581 | 15.062 | Spc97_Spc98 (PF04130, IPR007259): Spc97 / Spc98 family |
204 |
TXNRD1 | interactor | 10 | 0.422 | 8.595 | Glutaredoxin (PF00462, IPR002109): Glutaredoxin Pyr_redox_2 (PF07992, IPR023753): Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim (PF02852, IPR004099): Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain |
205 |
U2AF2 | protein found in more fusions | 37 | 0.481 | 55.962 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transformer (PF06495, IPR010519): Fruit fly transformer protein |
206 |
UBASH3B | interactor | 21 | 0.500 | 19.976 | His_Phos_1 (PF00300, IPR013078, SM00855): Histidine phosphatase superfamily (branch 1) UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain 2_5_RNA_ligase2 (PF13563): 2'-5' RNA ligase superfamily SH3_9 (PF14604, IPR001452): Variant SH3 domain |
207 |
UBL4A | interactor | 25 | 0.410 | 43.919 | ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
208 |
UNK | interactor | 22 | 0.342 | 32.291 | MbeD_MobD (PF04899, IPR006983): MbeD/MobD like NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450) zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) zf-CCCH_2 (PF14608): RNA-binding, Nab2-type zinc finger Torus (PF16131, IPR032297): Torus domain |
209 |
VAV1 | oncoprotein | 9 | 0.722 | 2.688 | PH (PF00169, IPR001849, SM00233): PH domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain SH2 (PF00017, IPR000980, SM00252): SH2 domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_1 (PF00018, IPR001452, SM00326): SH3 domain CAMSAP_CH (PF11971, IPR022613): CAMSAP CH domain |
210 |
VCAM1 | interactor | 40 | 0.285 | 130.744 | C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain |
211 |
VCP | protein found in more fusions | 61 | 0.312 | 365.660 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2 CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain TniB (PF05621, IPR008868): Bacterial TniB protein Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944) |
212 |
XPO1 | interactor | 67 | 0.182 | 820.024 | CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain Xpo1 (PF08389, IPR013598): Exportin 1-like protein Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region |
213 |
YBX1 | oncoprotein | 42 | 0.272 | 220.393 | CSD (PF00313, IPR002059): 'Cold-shock' DNA-binding domain PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal FXR_C1 (PF16096, IPR032172): Fragile X-related 1 protein C-terminal region 2 |
214 |
YWHAB | interactor | 30 | 0.402 | 61.095 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein Virulence_fact (PF13769, IPR025989): Virulence factor |
215 |
YWHAE | oncoprotein | 48 | 0.343 | 196.702 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |
216 |
YWHAQ | interactor | 49 | 0.337 | 196.054 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |
217 |
YWHAZ | protein found in more fusions | 43 | 0.307 | 151.536 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |
218 |
ZAP70 | interactor | 14 | 0.551 | 9.019 | Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase SH2 (PF00017, IPR000980, SM00252): SH2 domain |
219 |
ZBTB1 | interactor | 7 | 0.667 | 1.159 | BTB (PF00651, IPR013069, SM00225): BTB/POZ domain zf-BED (PF02892, IPR003656, SM00614): BED zinc finger zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies) zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger |