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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)116
The number (and %) of the onco-proteins32 (27.59 %)
The number (and %) of the tumor suppressors10 (8.62 %)
Total number of binary PPIs (saturation %)587 (8.80 %)
The number (and %) of affected PPIs116 (19.76 %)
The number of possible different fusions27
PPI diameter4
PPI radius2
The average degree of PPI9.276
Assortativity coefficient-0.2580
The network average Clustering coefficient0.499
The number (and %) of a zero Clustering coefficients12 (10.34 %)
The number (and %) of a zero Betweenness Centrality26 (22.41 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: SIPA1L3,RBFOX2 All fusions
Proteins found in more fusions PTBP1 (see 1 fusions); MAGED1 (see 1 fusions); VCP (see 4 fusions); PRMT5 (see 1 fusions); U2AF2 (see 2 fusions); MAPK1IP1L (see 1 fusions); SFN (see 1 fusions); FAM136A (see 1 fusions); CUL3 (see 1 fusions); ATXN1 (see 3 fusions); SRPK2 (see 1 fusions); RBPMS (see 1 fusions); VAC14 (see 1 fusions); RBFOX2 (see 3 fusions); KHDRBS1 (see 1 fusions); FMNL1 (see 1 fusions); APC (see 1 fusions); ATN1 (see 1 fusions); QKI (see 3 fusions); DAZAP2 (see 2 fusions); APH1A (see 2 fusions); QKI/RBFOX1 (see 1 fusions); DDX5 (see 1 fusions); MATR3 (see 4 fusions); RPA1 (see 1 fusions); TOLLIP (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 SIPA1L3parental protein220.216715.193IncA (PF04156, IPR007285): IncA protein
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
Rap_GAP (PF02145, IPR000331): Rap/ran-GAP
SPAR_C (PF11881, IPR021818): C-terminal domain of SPAR protein
2 RBFOX2parental protein940.0707830.327RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Fox-1_C (PF12414, IPR025670): Calcitonin gene-related peptide regulator C terminal
3 ANKRD40interactor31.0000Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
4 APCsuppressor80.095273.873APC_15aa (PF05972, IPR009240): APC 15 residue motif
APC_basic (PF05956, IPR009234): APC basic domain
APC_r (PF05923): APC repeat
Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
EB1_binding (PF05937, IPR009232): EB-1 Binding Domain
FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid)
SAMP (PF05924, IPR009224): SAMP Motif
Suppressor_APC (PF11414, IPR026831): Adenomatous polyposis coli tumour suppressor protein
AIF_C (PF14721, IPR029324): Apoptosis-inducing factor, mitochondrion-associated, C-term
SAS4 (PF15460, IPR029184): Something about silencing, SAS, complex subunit 4
Arm_APC_u3 (PF16629): Armadillo-associated region on APC
APC_u5 (PF16630): Unstructured region on APC between 1st and 2nd catenin-bdg motifs
APC_u9 (PF16633): Unstructured region on APC between 1st two creatine-rich regions
APC_u13 (PF16634): Unstructured region on APC between APC_crr and SAMP
APC_u14 (PF16635): Unstructured region on APC between SAMP and APC_crr
APC_u15 (PF16636): Unstructured region on APC between APC_crr regions 5 and 6
APC_N_CC (PF16689, IPR032038): Coiled-coil N-terminus of APC, dimerisation domain
5 APH1Aoncoprotein40.6673.392Aph-1 (PF06105, IPR009294): Aph-1 protein
6 ATN1protein found in more fusions80.6195.939Atrophin-1 (PF03154, IPR002951): Atrophin-1 family
7 ATXN1protein found in more fusions200.234231.895AXH (PF08517, IPR013723, SM00536): Ataxin-1 and HBP1 module (AXH)
Spt20 (PF12090, IPR021950): Spt20 family
ATXN-1_C (PF12547, IPR020997): Capicua transcriptional repressor modulator
Cnd1_N (PF12922, IPR024324): non-SMC mitotic condensation complex subunit 1, N-term
8 ATXN1Linteractor80.5717.405AXH (PF08517, IPR013723, SM00536): Ataxin-1 and HBP1 module (AXH)
9 ATXN2interactor80.5717.499LsmAD (PF06741, IPR009604): LsmAD domain
PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region
DUF3446 (PF11928, IPR021849): Domain of unknown function (DUF3446)
Spt20 (PF12090, IPR021950): Spt20 family
SM-ATX (PF14438, IPR025852): Ataxin 2 SM domain
10 BCS1Linteractor100AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
BCS1_N (PF08740, IPR014851, SM01024): BCS1 N terminal
AAA_25 (PF13481): AAA domain
11 BMI1oncoprotein160.28673.819zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
12 BOLLinteractor31.0000NO_synthase (PF02898, IPR004030): Nitric oxide synthase, oxygenase domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
13 BRD7suppressor100HcyBio (PF01837, IPR002708): Homocysteine biosynthesis enzyme, sulfur-incorporation
GntR (PF00392, IPR000524, SM00345): Bacterial regulatory proteins, gntR family
Presenilin (PF01080, IPR001108): Presenilin
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
DUF3512 (PF12024, IPR021900): Domain of unknown function (DUF3512)
MAJIN (PF15077, IPR027816): Membrane-anchored junction protein
14 C19orf52interactor2011.439DUF2366 (PF10171, IPR019322): Uncharacterised conserved protein (DUF2366)
15 C1orf94interactor120.45532.839DUF4688 (PF15752, IPR031496): Domain of unknown function (DUF4688)
16 CAMK2Boncoprotein60.300135.586CaMKII_AD (PF08332, IPR013543): Calcium/calmodulin dependent protein kinase II association domain
Pkinase (PF00069, IPR000719): Protein kinase domain
17 CAPZA2interactor100.68949.413F-actin_cap_A (PF01267, IPR002189): F-actin capping protein alpha subunit
18 CEP135interactor50.50036.547DUF724 (PF05266, IPR007930): Protein of unknown function (DUF724)
ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
LPP (PF04728, IPR006817): Lipoprotein leucine-zipper
RasGAP_C (PF03836, IPR000593): RasGAP C-terminus
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
TPD52 (PF04201, IPR007327): Tumour protein D52 family
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
zf-C4H2 (PF10146, IPR018482): Zinc finger-containing protein
KASH_CCD (PF14662, IPR028168): Coiled-coil region of CCDC155 or KASH
HMMR_N (PF15905, IPR031787): Hyaluronan mediated motility receptor N-terminal
GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor
PKcGMP_CC (PF16808, IPR031831): Coiled-coil N-terminus of cGMP-dependent protein kinase
19 CEP152interactor50.50024.661bZIP_1 (PF00170, IPR004827): bZIP transcription factor
CDC37_N (PF03234, IPR013855, SM01071): Cdc37 N terminal kinase binding
CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
DUF641 (PF04859, IPR006943): Plant protein of unknown function (DUF641)
ZapB (PF06005, IPR009252): Cell division protein ZapB
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
Ribosomal_S13 (PF00416, IPR001892): Ribosomal protein S13/S18
FAD-SLDH (PF12318, IPR024651): Membrane bound FAD containing D-sorbitol dehydrogenase
YtxH (PF12732, IPR024623): YtxH-like protein
ADH_zinc_N_2 (PF13602): Zinc-binding dehydrogenase
TolA_bind_tri (PF16331, IPR032519): TolA binding protein trimerisation
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
20 CEP164interactor21.0000DUF883 (PF05957, IPR010279): Bacterial protein of unknown function (DUF883)
DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948)
TBPIP (PF07106, IPR010776): Tat binding protein 1(TBP-1)-interacting protein (TBPIP)
WW (PF00397, IPR001202, SM00456): WW domain
KxDL (PF10241, IPR019371): Uncharacterized conserved protein
XhlA (PF10779, IPR019715): Haemolysin XhlA
KfrA_N (PF11740, IPR021104): Plasmid replication region DNA-binding N-term
DUF3807 (PF12720, IPR024526): Protein of unknown function (DUF3807)
21 CHAF1Ainteractor50.33313.452CAF-1_p150 (PF11600): Chromatin assembly factor 1 complex p150 subunit, N-terminal
CAF1A (PF12253, IPR022043): Chromatin assembly factor 1 subunit A
CAF1-p150_C2 (PF15539, IPR029105): CAF1 complex subunit p150, region binding to CAF1-p60 at C-term
CAF1-p150_N (PF15557, IPR029091): CAF1 complex subunit p150, region binding to PCNA
22 CLNS1Ainteractor40.8330.667Voldacs (PF03517): Regulator of volume decrease after cellular swelling
23 COPRSinteractor21.0000COPR5 (PF15340, IPR029289): Cooperator of PRMT5 family
24 CUL3protein found in more fusions340.295365.189Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
25 DAB1interactor90.55614.905PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID)
26 DAZAP2protein found in more fusions120.63623.370DAZAP2 (PF11029, IPR022730): DAZ associated protein 2 (DAZAP2)
27 DDX5oncoprotein210.45386.984DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
P68HR (PF08061, IPR012587): P68HR (NUC004) repeat
ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
28 DEDD2interactor50.5001.833DED (PF01335, IPR001875, SM00031): Death effector domain
29 DMRTB1interactor31.0000DM (PF00751, IPR001275, SM00301): DM DNA binding domain
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
VIR_N (PF15912, IPR031801): Virilizer, N-terminal
30 DPH2interactor100Diphthamide_syn (PF01866, IPR002728): Putative diphthamide synthesis protein
31 DYRK1Boncoprotein200Pkinase (PF00069, IPR000719): Protein kinase domain
32 EIF4G3interactor30.6670.133MA3 (PF02847, IPR003891, SM00544): MA3 domain
MIF4G (PF02854, IPR003890, SM00543): MIF4G domain
W2 (PF02020, IPR003307, SM00515): eIF4-gamma/eIF5/eIF2-epsilon
33 ELAVL1oncoprotein330.1731070.415RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
34 ELAVL2interactor50.6003.967RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
35 ESR1suppressor200.322172.608Oest_recep (PF02159, IPR001292): Oestrogen receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal
36 ESR2suppressor50.6678.050zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
ERbeta_N (PF12497, IPR021064): Estrogen receptor beta
37 FAM136Aprotein found in more fusions200DUF842 (PF05811, IPR008560): Eukaryotic protein of unknown function (DUF842)
38 FBXO7interactor40.5003.012Elongin_A (PF06881, IPR010684): RNA polymerase II transcription factor SIII (Elongin) subunit A
PI31_Prot_N (PF11566, IPR021625): PI31 proteasome regulator N-terminal
F-box-like (PF12937, IPR001810): F-box-like
39 FMNL1protein found in more fusions40.33321.540CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
Drf_FH3 (PF06367, IPR010472, SM01139): Diaphanous FH3 Domain
Drf_GBD (PF06371, IPR010473, SM01140): Diaphanous GTPase-binding Domain
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
FH2 (PF02181, IPR015425, SM00498): Formin Homology 2 Domain
SlyX (PF04102, IPR007236): SlyX
FNIP_M (PF14637, IPR028085): Folliculin-interacting protein middle domain
PRIMA1 (PF16101): Proline-rich membrane anchor 1
ABC_tran_CTD (PF16326, IPR032524): ABC transporter C-terminal domain
40 FNDC3Binteractor30.6671.817fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
Pur_ac_phosph_N (PF16656, IPR015914): Purple acid Phosphatase, N-terminal domain
41 GLIS2interactor21.0000zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
FOXP-CC (PF16159, IPR032354): FOXP coiled-coil domain
42 GPATCH8interactor50.5004.371G-patch (PF01585, IPR000467, SM00443): G-patch domain
Peptidase_S64 (PF08192, IPR012985): Peptidase family S64
SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region
Use1 (PF09753, IPR019150): Membrane fusion protein Use1
zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
SOBP (PF15279, IPR026092): Sine oculis-binding protein
CCDC106 (PF15794, IPR031591): Coiled-coil domain-containing protein 106
43 GTF2A1Linteractor21.0000TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
44 HELZinteractor31.0000PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
AAA_11 (PF13086): AAA domain
AAA_12 (PF13087): AAA domain
TetR_C_8 (PF14278): Transcriptional regulator C-terminal region
45 HNRNPABinteractor130.39744.926CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain
GRP (PF07172, IPR010800): Glycine rich protein family
NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
DUF2462 (PF09495, IPR019034): Protein of unknown function (DUF2462)
46 HNRNPFinteractor190.45677.247RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Spot_14 (PF07084, IPR009786): Thyroid hormone-inducible hepatic protein Spot 14
zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger
47 HNRNPH2interactor150.462121.580RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger
48 HNRNPKoncoprotein230.50674.651ROKNT (PF08067, IPR012987): ROKNT (NUC014) domain
KH_1 (PF00013, IPR004088, SM00322): KH domain
49 HOXA5interactor30.6676.334Chorion_2 (PF03964, IPR005649): Chorion family 2
Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein
Terminase_5 (PF06056, IPR010332): Putative ATPase subunit of terminase (gpP-like)
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
50 IQGAP1interactor160.442121.101CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
DUF87 (PF01935, IPR002789): Domain of unknown function DUF87
IDEAL (PF08858, IPR014957, SM00914): IDEAL domain
IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase
RasGAP_C (PF03836, IPR000593): RasGAP C-terminus
WW (PF00397, IPR001202, SM00456): WW domain
51 JMJD4interactor100Cupin_4 (PF08007, IPR003347): Cupin superfamily protein
JmjC (PF02373, IPR003347, SM00558): JmjC domain, hydroxylase
52 KHDRBS1protein found in more fusions170.55854.090KH_1 (PF00013, IPR004088, SM00322): KH domain
Qua1 (PF16274, IPR032571): Qua1 domain
Sam68-YY (PF16568, IPR032335): Tyrosine-rich domain of Sam68
53 LARP4Binteractor41.0000La (PF05383, IPR006630, SM00715): La domain
54 LATS2suppressor50.33316.075Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
55 MAGED1protein found in more fusions170.283234.501MAGE (PF01454, IPR002190): MAGE family
56 MAPK1IP1Lprotein found in more fusions40.333116.573MISS (PF15822, IPR031653): MAPK-interacting and spindle-stabilising protein-like
57 MATR3protein found in more fusions190.53653.905DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-U1 (PF06220, IPR013085, SM00451): U1 zinc finger
Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54
zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding
RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
FAM60A (PF15396, IPR026065): Protein Family FAM60A
58 MBNL1interactor60.7334.657zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
zf-CCCH_3 (PF15663): Zinc-finger containing family
59 MED7interactor40.6672.663Med7 (PF05983, IPR009244): MED7 protein
DotU (PF09850, IPR017732): Type VI secretion system protein DotU
60 MSI2oncoprotein80.5713.978NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
61 MYH9suppressor150.438138.493IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain
Myosin_tail_1 (PF01576, IPR002928): Myosin tail
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
62 MYO18Ainteractor90.77847.007Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1
IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_tail_1 (PF01576, IPR002928): Myosin tail
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2
63 MYO19interactor81.0000IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
64 MYO1Cinteractor150.457119.902IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_TH1 (PF06017, IPR010926): Unconventional myosin tail, actin- and lipid-binding
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
65 NAF1interactor30.6672.000AF-4 (PF05110, IPR007797): AF-4 proto-oncoprotein
Gar1 (PF04410, IPR007504): Gar1/Naf1 RNA binding region
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
66 NINLinteractor50.40017.270PD40 (PF07676, IPR011659): WD40-like Beta Propeller Repeat
TBCA (PF02970, IPR004226): Tubulin binding cofactor A
DUF2389 (PF09493, IPR012663): Tryptophan-rich protein (DUF2389)
Golgin_A5 (PF09787, IPR019177): Golgin subfamily A member 5
EF-hand_1 (PF00036, IPR002048, SM00054): EF hand
EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding
Muted (PF14942, IPR017243): Organelle biogenesis, Muted-like protein
FAM184 (PF15665): Family with sequence similarity 184, A and B
TRAF_BIRC3_bd (PF16673, IPR032070): TNF receptor-associated factor BIRC3 binding domain
67 NR2E3interactor40.5001.833zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
68 NTRK1oncoprotein400.206712.160I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
69 ODF2interactor40.66717.409ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
NAT (PF04768, IPR006855): NAT, N-acetyltransferase, of N-acetylglutamate synthase
Invasin_D3 (PF09134, IPR015217): Invasin, domain 3
Mt_ATP-synt_D (PF05873, IPR008689): ATP synthase D chain, mitochondrial (ATP5H)
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding
TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
70 OTUD4interactor30.33385.080OTU (PF02338, IPR003323): OTU-like cysteine protease
Presenilin (PF01080, IPR001108): Presenilin
Peptidase_C65 (PF10275, IPR019400): Peptidase C65 Otubain
71 PARLinteractor100Rhomboid (PF01694, IPR022764): Rhomboid family
72 PJA1interactor31.0000zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
73 PLEKHB1oncoprotein21.0000PH (PF00169, IPR001849, SM00233): PH domain
Bacteriocin_IIc (PF10439, IPR019493): Bacteriocin class II with double-glycine leader peptide
74 POLR3Dinteractor40.5001.833Atrophin-1 (PF03154, IPR002951): Atrophin-1 family
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
75 PPP1CBinteractor140.473136.606Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
76 PRMT5protein found in more fusions100.41720.715PRMT5 (PF05185, IPR025799): PRMT5 arginine-N-methyltransferase
77 PRRC2Ainteractor140.35252.630BAT2_N (PF07001, IPR009738): BAT2 N-terminus
MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
78 PSMA3interactor150.31969.762Proteasome (PF00227, IPR001353): Proteasome subunit
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
79 PSMF1interactor60.6002.733PI31_Prot_C (PF08577, IPR013886): PI31 proteasome regulator
PI31_Prot_N (PF11566, IPR021625): PI31 proteasome regulator N-terminal
80 PTBP1oncoprotein170.55842.155RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
81 PUM1interactor80.42918.402K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
PUF (PF00806, IPR001313, SM00025): Pumilio-family RNA binding repeat
YppG (PF14179, IPR025555): YppG-like protein
82 PUM2interactor50.8330.310PC4 (PF02229, IPR003173): Transcriptional Coactivator p15 (PC4)
ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26
PUF (PF00806, IPR001313, SM00025): Pumilio-family RNA binding repeat
83 QKIprotein found in more fusions130.40939.883KH_1 (PF00013, IPR004088, SM00322): KH domain
STAR_dimer (PF16544, IPR032377): Homodimerisation region of STAR domain protein
Quaking_NLS (PF16551, IPR032367): Putative nuclear localisation signal of quaking
84 RBFOX1protein found in more fusions160.40047.015RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Fox-1_C (PF12414, IPR025670): Calcitonin gene-related peptide regulator C terminal
85 RBM22interactor21.0000FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Torus (PF16131, IPR032297): Torus domain
86 RBM23interactor80.32115.386RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
RBM39linker (PF15519, IPR029123): linker between RRM2 and RRM3 domains in RBM39 protein
RSRP (PF17069): Arginine/Serine-Rich protein 1
87 RBM38suppressor100RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
88 RBM42interactor40.8330.222RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PRIMA1 (PF16101): Proline-rich membrane anchor 1
89 RBMS1interactor21.0000RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
90 RBPMSprotein found in more fusions160.371115.162RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
91 RBPMS2interactor100RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
92 REREoncoprotein50.7005.911Atrophin-1 (PF03154, IPR002951): Atrophin-1 family
BAH (PF01426, IPR001025, SM00439): BAH domain
ELM2 (PF01448, IPR000949): ELM2 domain
POPLD (PF08170, IPR012590): POPLD (NUC188) domain
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
GATA (PF00320, IPR000679, SM00401): GATA zinc finger
93 RHOXF2interactor150.36359.928DUF367 (PF04034, IPR007177): Domain of unknown function (DUF367)
GRP (PF07172, IPR010800): Glycine rich protein family
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
94 RIOK1interactor50.7008.708RIO1 (PF01163, IPR018934): RIO1 family
95 RNF8suppressor40.6670.582FHA (PF00498, IPR000253, SM00240): FHA domain
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies)
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
DUF4665 (PF15679, IPR031389): Domain of unknown function (DUF4665)
96 RPA1suppressor210.426111.950Rep-A_N (PF04057, IPR007199): Replication factor-A protein 1, N-terminal domain
Rep_fac-A_C (PF08646, IPR013955): Replication factor-A C terminal domain
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
REPA_OB_2 (PF16900, IPR031657): Replication protein A OB domain
97 RPA2oncoprotein190.45698.403RPA_C (PF08784, IPR014892): Replication protein A C terminal
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
RMI2 (PF16100, IPR032245): RecQ-mediated genome instability protein 2
98 RPA3interactor200.47485.060Rep_fac-A_3 (PF08661, IPR013970): Replication factor A protein 3
99 RPGRIP1Linteractor60.40014.972bZIP_1 (PF00170, IPR004827): bZIP transcription factor
C2 (PF00168, IPR000008, SM00239): C2 domain
DivIC (PF04977, IPR007060): Septum formation initiator
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
FtsL (PF04999, IPR011922): Cell division protein FtsL
T3SS_needle_F (PF09392, IPR021123): Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
C2-C2_1 (PF11618, IPR021656): First C2 domain of RPGR-interacting protein 1
BNIP2 (PF12496, IPR022181): Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
DUF4497 (PF14924): Protein of unknown function (DUF4497)
100 SF3A1interactor90.8330.869TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
Surp (PF01805, IPR000061, SM00648): Surp module
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
PRP21_like_P (PF12230, IPR022030): Pre-mRNA splicing factor PRP21 like protein
101 SFNsuppressor70.40019.58114-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
102 SMN1interactor60.7001.650SMN (PF06003, IPR010304): Survival motor neuron protein (SMN)
103 SNRPCinteractor110.400113.757zf-U1 (PF06220, IPR013085, SM00451): U1 zinc finger
104 SRPK2oncoprotein190.307202.184DUF1387 (PF07139, IPR009816): Protein of unknown function (DUF1387)
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
Pkinase (PF00069, IPR000719): Protein kinase domain
S-antigen (PF05756, IPR008825): S-antigen protein
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
105 SYNPOinteractor90.77812.367Calsarcin (PF05556, IPR008438): Calcineurin-binding protein (Calsarcin)
106 TOLLIPprotein found in more fusions90.71411.201C2 (PF00168, IPR000008, SM00239): C2 domain
CUE (PF02845, IPR003892, SM00546): CUE domain
107 TRMT61Ainteractor100GCD14 (PF08704, IPR014816): tRNA methyltransferase complex GCD14 subunit
GCD14_N (PF14801): tRNA methyltransferase complex GCD14 subunit N-term
108 U2AF2protein found in more fusions200.46288.551RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Transformer (PF06495, IPR010519): Fruit fly transformer protein
109 UBAP2interactor31.0000Alpha_GJ (PF03229, IPR004913): Alphavirus glycoprotein J
API5 (PF05918, IPR008383): Apoptosis inhibitory protein 5 (API5)
CUE (PF02845, IPR003892, SM00546): CUE domain
HlyE (PF06109, IPR027018): Haemolysin E (HlyE)
MGC-24 (PF05283, IPR007947): Multi-glycosylated core protein 24 (MGC-24), sialomucin
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
DUF3697 (PF12478, IPR022166): Ubiquitin-associated protein 2
UBA_4 (PF14555): UBA-like domain
110 UNKinteractor80.35729.588MbeD_MobD (PF04899, IPR006983): MbeD/MobD like
NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region
zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
zf-CCCH_2 (PF14608): RNA-binding, Nab2-type zinc finger
Torus (PF16131, IPR032297): Torus domain
111 VAC14oncoprotein60.40014.572TAF6_C (PF07571, IPR011442): TAF6 C-terminal HEAT repeat domain
HEAT (PF02985, IPR000357): HEAT repeat
Vac14_Fig4_bd (PF11916, IPR021841): Vacuolar protein 14 C-terminal Fig4p binding
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
112 VCPprotein found in more fusions170.38399.476AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2
CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain
TniB (PF05621, IPR008868): Bacterial TniB protein
Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain
DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944)
113 WDR83interactor80.35766.844WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
114 YWHABinteractor120.28880.52814-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
Virulence_fact (PF13769, IPR025989): Virulence factor
115 YWHAQinteractor150.314112.92814-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
116 ZNF137Pinteractor100NA

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