1 |
AP3D1 | parental protein | 37 | 0.129 | 1122.423 | Adaptin_N (PF01602, IPR002553): Adaptin N terminal region Lamp (PF01299, IPR002000): Lysosome-associated membrane glycoprotein (Lamp) RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1 SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal AP3D1 (PF06375): AP-3 complex subunit delta-1 |
2 |
TRAPPC8 | parental protein | 18 | 0.346 | 350.015 | TRAPPC-Trs85 (PF12739, IPR024420): ER-Golgi trafficking TRAPP I complex 85 kDa subunit SNAP (PF14938): Soluble NSF attachment protein, SNAP |
3 |
ACAT2 | interactor | 3 | 1.000 | 0 | Thiolase_C (PF02803, IPR020617): Thiolase, C-terminal domain Thiolase_N (PF00108, IPR020616): Thiolase, N-terminal domain |
4 |
AGO3 | interactor | 5 | 1.000 | 0 | ArgoL1 (PF08699, IPR014811, SM01163): Argonaute linker 1 domain PAZ (PF02170, IPR003100, SM00949): PAZ domain Piwi (PF02171, IPR003165, SM00950): Piwi domain ArgoN (PF16486, IPR032474): N-terminal domain of argonaute ArgoMid (PF16487, IPR032473): Mid domain of argonaute ArgoL2 (PF16488, IPR032472): Argonaute linker 2 domain |
5 |
AP3B1 | interactor | 14 | 0.396 | 79.398 | Adaptin_N (PF01602, IPR002553): Adaptin N terminal region AP3B1_C (PF14796, IPR029390): Clathrin-adaptor complex-3 beta-1 subunit C-terminal SEEEED (PF14797, IPR029394): Serine-rich region of AP3B1, clathrin-adaptor complex |
6 |
AP3B2 | interactor | 6 | 0.533 | 10.168 | Adaptin_N (PF01602, IPR002553): Adaptin N terminal region Dsh_C (PF12316, IPR024580): Segment polarity protein dishevelled (Dsh) C terminal AP3B1_C (PF14796, IPR029390): Clathrin-adaptor complex-3 beta-1 subunit C-terminal |
7 |
AP3M1 | interactor | 14 | 0.385 | 105.885 | Adap_comp_sub (PF00928, IPR008968): Adaptor complexes medium subunit family Clat_adaptor_s (PF01217, IPR022775): Clathrin adaptor complex small chain |
8 |
AP3S1 | interactor | 12 | 0.424 | 31.559 | Clat_adaptor_s (PF01217, IPR022775): Clathrin adaptor complex small chain |
9 |
AP3S2 | interactor | 6 | 0.733 | 3.367 | Clat_adaptor_s (PF01217, IPR022775): Clathrin adaptor complex small chain |
10 |
ARRB1 | interactor | 5 | 0.700 | 1.708 | Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain |
11 |
ARRB2 | interactor | 10 | 0.378 | 23.808 | Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain |
12 |
BARD1 | suppressor | 4 | 0.333 | 5.805 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_5 (PF13857): Ankyrin repeats (many copies) zf-RING_6 (PF14835): zf-RING of BARD1-type protein BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain |
13 |
CDC73 | suppressor | 5 | 0.900 | 1.904 | CDC73_C (PF05179, IPR007852): RNA pol II accessory factor, Cdc73 family, C-terminal CDC73_N (PF16050, IPR032041): Paf1 complex subunit CDC73 N-terminal |
14 |
CDK11B | oncoprotein | 4 | 1.000 | 0 | DDHD (PF02862, IPR004177, SM01127): DDHD domain DivIC (PF04977, IPR007060): Septum formation initiator Pkinase (PF00069, IPR000719): Protein kinase domain DUF4748 (PF15932, IPR031833): Domain of unknown function (DUF4748) |
15 |
CENPJ | interactor | 3 | 0.667 | 0.500 | DASH_Hsk3 (PF08227, IPR013183): DASH complex subunit Hsk3 like DUF1795 (PF08786, IPR014894): Domain of unknown function (DUF1795) DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) Rota_VP2 (PF05087, IPR007779): Rotavirus VP2 protein Tcp10_C (PF07202, IPR009852): T-complex protein 10 C-terminus TSC22 (PF01166, IPR000580): TSC-22/dip/bun family AAA_23 (PF13476): AAA domain DUF4140 (PF13600, IPR025554): N-terminal domain of unknown function (DUF4140) |
16 |
CEP19 | interactor | 2 | 1.000 | 0 | CEP19 (PF14933, IPR029412): CEP19-like protein |
17 |
CLTB | interactor | 6 | 0.533 | 7.786 | Clathrin_lg_ch (PF01086, IPR000996): Clathrin light chain |
18 |
CLTC | oncoprotein | 9 | 0.333 | 60.697 | Clathrin-link (PF09268, IPR015348): Clathrin, heavy-chain linker Clathrin_propel (PF01394, IPR022365): Clathrin propeller repeat Clathrin (PF00637, IPR000547, SM00299): Region in Clathrin and VPS Clathrin_H_link (PF13838): Clathrin-H-link |
19 |
COPG1 | protein found in more fusions | 6 | 0.600 | 5.249 | Adaptin_N (PF01602, IPR002553): Adaptin N terminal region COP-gamma_platf (PF08752, IPR013040): Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla (PF16381, IPR032154): Coatomer subunit gamma-1 C-terminal appendage platform |
20 |
DAP3 | interactor | 3 | 1.000 | 0 | DAP3 (PF10236, IPR019368): Mitochondrial ribosomal death-associated protein 3 |
21 |
DTNBP1 | interactor | 8 | 0.571 | 8.500 | Dysbindin (PF04440, IPR007531): Dysbindin (Dystrobrevin binding protein 1) Exonuc_VII_L (PF02601, IPR020579): Exonuclease VII, large subunit DUF2730 (PF10805, IPR020269): Protein of unknown function (DUF2730) |
22 |
EGFR | oncoprotein | 10 | 0.417 | 146.381 | Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT) GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV |
23 |
EPB41L3 | suppressor | 6 | 0.533 | 10.377 | 4_1_CTD (PF05902, IPR008379): 4.1 protein C-terminal domain (CTD) FA (PF08736, IPR014847): FERM adjacent (FA) FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain FERM_M (PF00373, IPR019748): FERM central domain FERM_N (PF09379, IPR018979): FERM N-terminal domain RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 SAB (PF04382, IPR007477): SAB domain |
24 |
F2R | interactor | 1 | 0 | 0 | 7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family) DUF412 (PF04217, IPR007334): Protein of unknown function, DUF412 |
25 |
FBXW7 | suppressor | 2 | 0 | 0 | Mem_trans (PF03547, IPR004776): Membrane transport protein WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 F-box-like (PF12937, IPR001810): F-box-like |
26 |
GRK5 | protein found in more fusions | 4 | 1.000 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain |
27 |
HTATSF1 | interactor | 3 | 0.667 | 2.105 | BUD22 (PF09073, IPR015158): BUD22 Conotoxin (PF02950, IPR004214): Conotoxin Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1 PSK (PF06404, IPR009438): Phytosulfokine precursor protein (PSK) RNA_polI_A34 (PF08208, IPR013240): DNA-directed RNA polymerase I subunit RPA34.5 RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
28 |
KLC2 | interactor | 4 | 0.500 | 13.724 | TPR_10 (PF13374, IPR011990): Tetratricopeptide repeat TPR_12 (PF13424): Tetratricopeptide repeat JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II |
29 |
NIN | oncoprotein | 2 | 0 | 0 | BRE1 (PF08647, IPR013956): BRE1 E3 ubiquitin ligase bZIP_1 (PF00170, IPR004827): bZIP transcription factor DivIC (PF04977, IPR007060): Septum formation initiator DivIVA (PF05103, IPR007793): DivIVA protein DUF342 (PF03961, IPR005646): Protein of unknown function (DUF342) ZapB (PF06005, IPR009252): Cell division protein ZapB FlaC_arch (PF05377, IPR008039): Flagella accessory protein C (FlaC) Fzo_mitofusin (PF04799, IPR006884): fzo-like conserved region Cnn_1N (PF07989, IPR012943): Centrosomin N-terminal motif 1 Rho_Binding (PF08912, IPR015008): Rho Binding TSC22 (PF01166, IPR000580): TSC-22/dip/bun family Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region DUF2205 (PF10224, IPR019357): Predicted coiled-coil protein (DUF2205) Kinetocho_Slk19 (PF12709, IPR024312): Central kinetochore-associated EF-hand_6 (PF13405, IPR002048): EF-hand domain EF-hand_7 (PF13499, IPR011992): EF-hand domain pair EF-hand_8 (PF13833, IPR002048): EF-hand domain pair Cep57_CLD_2 (PF14197, IPR025925): Centrosome localisation domain of PPC89 FlxA (PF14282, IPR025577): FlxA-like protein DUF4472 (PF14739, IPR029329): Domain of unknown function (DUF4472) Muted (PF14942, IPR017243): Organelle biogenesis, Muted-like protein DUF4665 (PF15679, IPR031389): Domain of unknown function (DUF4665) PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1 |
30 |
NTRK1 | oncoprotein | 25 | 0.145 | 966.066 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain |
31 |
PAXIP1 | interactor | 7 | 0.143 | 79.138 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain IPT (PF01745, IPR002648, SM00429): Isopentenyl transferase SURF6 (PF04935, IPR007019): Surfeit locus protein 6 DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052) CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance PTCB-BRCT (PF12738, IPR001357): twin BRCT domain BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT (PF16759, IPR031916): DNA ligase 3 BRCT domain RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain |
32 |
POU5F1 | oncoprotein | 5 | 0.500 | 5.486 | Pou (PF00157, IPR000327, SM00352): Pou domain - N-terminal to homeobox domain Homeobox (PF00046, IPR001356, SM00389): Homeobox domain |
33 |
RBM25 | interactor | 6 | 0.333 | 66.783 | Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1 PWI (PF01480, IPR002483, SM00311): PWI domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SMN (PF06003, IPR010304): Survival motor neuron protein (SMN) SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal MIP-T3 (PF10243): Microtubule-binding protein MIP-T3 DUF3441 (PF11923, IPR021846): Domain of unknown function (DUF3441) U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4778 (PF16008, IPR031958): Domain of unknown function (DUF4778) |
34 |
RNF13 | interactor | 3 | 0.667 | 0.333 | DNA_ligase_ZBD (PF03119, IPR004149): NAD-dependent DNA ligase C4 zinc finger domain PA (PF02225, IPR003137): PA domain zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain FAM176 (PF14851): FAM176 family STAC2_u1 (PF16664): Unstructured on SH3 and cysteine-rich domain-containing protein 2 |
35 |
RUFY1 | interactor | 7 | 0.600 | 4.904 | DM (PF00751, IPR001275, SM00301): DM DNA binding domain FAA_hydrolase_N (PF09298, IPR015377): Fumarylacetoacetase N-terminal DUF641 (PF04859, IPR006943): Plant protein of unknown function (DUF641) DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger RUN (PF02759, IPR004012, SM00593): RUN domain Tektin (PF03148, IPR000435): Tektin family |
36 |
STAU1 | protein found in more fusions | 8 | 0.524 | 15.259 | dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif Staufen_C (PF16482, IPR032478): Staufen C-terminal domain |
37 |
TECPR1 | interactor | 3 | 1.000 | 0 | DUF1768 (PF08719, IPR012816): Domain of unknown function (DUF1768) Pex24p (PF06398, IPR010482): Integral peroxisomal membrane peroxin PH (PF00169, IPR001849, SM00233): PH domain Hyd_WA (PF06462, IPR006624, SM00706): Propeller |
38 |
TRAPPC10 | protein found in more fusions | 9 | 0.929 | 0.508 | Foie-gras_1 (PF11817, IPR021773): Foie gras liver health family 1 TRAPPC10 (PF12584, IPR022233): Trafficking protein particle complex subunit 10, TRAPPC10 |
39 |
TRAPPC11 | protein found in more fusions | 11 | 0.533 | 105.183 | DUF974 (PF06159, IPR010378): Protein of unknown function (DUF974) Foie-gras_1 (PF11817, IPR021773): Foie gras liver health family 1 Gryzun-like (PF12742, IPR025876): Gryzun, putative Golgi trafficking |
40 |
TRAPPC12 | interactor | 14 | 0.577 | 171.693 | TPR_6 (PF13174, IPR019734): Tetratricopeptide repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat |
41 |
TRAPPC13 | interactor | 4 | 1.000 | 0 | DUF974 (PF06159, IPR010378): Protein of unknown function (DUF974) Transglut_C (PF00927, IPR008958): Transglutaminase family, C-terminal ig like domain Trs65 (PF12735, IPR024662): TRAPP trafficking subunit Trs65 |
42 |
TRAPPC2 | interactor | 10 | 0.806 | 3.011 | Sedlin_N (PF04628, IPR006722): Sedlin, N-terminal conserved region |
43 |
TRAPPC2L | interactor | 11 | 0.711 | 6.511 | Sedlin_N (PF04628, IPR006722): Sedlin, N-terminal conserved region |
44 |
TRAPPC3 | interactor | 9 | 0.611 | 90.769 | TRAPP (PF04051, IPR007194): Transport protein particle (TRAPP) component |
45 |
TRAPPC3L | interactor | 9 | 0.861 | 1.413 | TRAPP (PF04051, IPR007194): Transport protein particle (TRAPP) component |
46 |
TRAPPC4 | interactor | 11 | 0.822 | 3.234 | Sybindin (PF04099, IPR007233): Sybindin-like family |
47 |
TRAPPC6B | interactor | 8 | 0.893 | 1.643 | TRAPP (PF04051, IPR007194): Transport protein particle (TRAPP) component |
48 |
TRAPPC9 | interactor | 8 | 0.786 | 79.534 | PMBR (PF09373, IPR018975): Pseudomurein-binding repeat TRAPPC9-Trs120 (PF08626, IPR013935): Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Vps23_core (PF09454, IPR017916): Vps23 core domain |
49 |
UNK | interactor | 3 | 0 | 14.851 | MbeD_MobD (PF04899, IPR006983): MbeD/MobD like NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450) zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) zf-CCCH_2 (PF14608): RNA-binding, Nab2-type zinc finger Torus (PF16131, IPR032297): Torus domain |
50 |
VAMP7 | interactor | 2 | 1.000 | 0 | Synaptobrevin (PF00957, IPR001388): Synaptobrevin Longin (PF13774, IPR010908): Regulated-SNARE-like domain |
51 |
VPS33A | interactor | 4 | 0.667 | 14.991 | Sec1 (PF00995, IPR001619): Sec1 family |
52 |
VPS33B | interactor | 4 | 0.667 | 14.991 | Sec1 (PF00995, IPR001619): Sec1 family |
53 |
VPS39 | protein found in more fusions | 3 | 1.000 | 0 | CNH (PF00780, IPR001180, SM00036): CNH domain Vps39_1 (PF10366, IPR019452): Vacuolar sorting protein 39 domain 1 Vps39_2 (PF10367, IPR019453): Vacuolar sorting protein 39 domain 2 Clathrin (PF00637, IPR000547, SM00299): Region in Clathrin and VPS |
54 |
VPS41 | interactor | 4 | 0.833 | 0.500 | Vps39_1 (PF10366, IPR019452): Vacuolar sorting protein 39 domain 1 Vps39_2 (PF10367, IPR019453): Vacuolar sorting protein 39 domain 2 Clathrin (PF00637, IPR000547, SM00299): Region in Clathrin and VPS zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
55 |
XPO1 | interactor | 15 | 0.362 | 117.841 | CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain Xpo1 (PF08389, IPR013598): Exportin 1-like protein Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region |