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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)212
The number (and %) of the onco-proteins55 (25.94 %)
The number (and %) of the tumor suppressors36 (16.98 %)
Total number of binary PPIs (saturation %)1631 (7.29 %)
The number (and %) of affected PPIs220 (13.49 %)
The number of possible different fusions45
PPI diameter4
PPI radius2
The average degree of PPI14.660
Assortativity coefficient-0.1682
The network average Clustering coefficient0.385
The number (and %) of a zero Clustering coefficients26 (12.26 %)
The number (and %) of a zero Betweenness Centrality31 (14.62 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: ALDOA,ACTA1 All fusions
Proteins found in more fusions USP25 (see 1 fusions); SOD2 (see 5 fusions); TPM2/MYH9 (see 1 fusions); CUL7 (see 2 fusions); CUL1 (see 3 fusions); CUL3 (see 1 fusions); SMARCB1 (see 12 fusions); MYC (see 2 fusions); UBE3A (see 1 fusions); TPM2 (see 1 fusions); LGALS3 (see 2 fusions); ACTG1 (see 5 fusions); ALDOA/CACNA1A (see 1 fusions); FANCA (see 1 fusions); HDAC5 (see 1 fusions); EP300 (see 1 fusions); PCNA (see 1 fusions); GC (see 1 fusions); SUZ12 (see 2 fusions); FUS/PKM (see 1 fusions); TKT (see 5 fusions); HSP90AA1 (see 6 fusions); HSP90AA1/PSMA3 (see 1 fusions); SFN (see 1 fusions); HUWE1 (see 4 fusions); HSP90AB1 (see 3 fusions); SRPK2 (see 1 fusions); HDAC4 (see 1 fusions); MAPK14 (see 1 fusions); ERBB3 (see 2 fusions); ETV6 (see 1 fusions); EGFR (see 2 fusions); MCM2 (see 1 fusions); BCAT2 (see 1 fusions); ALDOA (see 2 fusions); KAT5 (see 3 fusions); SHC1 (see 1 fusions); ECHS1 (see 1 fusions); PRKCE (see 3 fusions); KCNAB2 (see 1 fusions); ERRFI1 (see 1 fusions); VIM (see 1 fusions); CTNNBL1 (see 1 fusions); GAPDH (see 5 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 ALDOAparental protein1080.1109814.856Glycolytic (PF00274, IPR000741): Fructose-bisphosphate aldolase class-I
2 ACTA1parental protein1120.05614073.681Actin (PF00022, IPR004000, SM00268): Actin
3 ABL1oncoprotein190.307123.900Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
F_actin_bind (PF08919, IPR015015, SM00808): F-actin binding
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
FRG2 (PF15315, IPR026245): Facioscapulohumeral muscular dystrophy candidate 2
4 ABLIM2interactor21.0000LIM (PF00412, IPR001781, SM00132): LIM domain
VHP (PF02209, IPR003128, SM00153): Villin headpiece domain
Med27 (PF11571, IPR021627): Mediator complex subunit 27
AbLIM_anchor (PF16182, IPR032402): Putative adherens-junction anchoring region of AbLIM
5 ABLIM3interactor21.0000LIM (PF00412, IPR001781, SM00132): LIM domain
VHP (PF02209, IPR003128, SM00153): Villin headpiece domain
zf-HYPF (PF07503, IPR011125): HypF finger
Vps39_2 (PF10367, IPR019453): Vacuolar sorting protein 39 domain 2
TNFR_c6 (PF00020, IPR001368, SM00208): TNFR/NGFR cysteine-rich region
AbLIM_anchor (PF16182, IPR032402): Putative adherens-junction anchoring region of AbLIM
6 ABRAinteractor30.6671.000Costars (PF14705, IPR027817): Costars
7 ACAA2interactor140.49527.074Thiolase_C (PF02803, IPR020617): Thiolase, C-terminal domain
Thiolase_N (PF00108, IPR020616): Thiolase, N-terminal domain
8 ACO2interactor120.33352.708Aconitase (PF00330, IPR001030): Aconitase family (aconitate hydratase)
Aconitase_C (PF00694, IPR000573): Aconitase C-terminal domain
9 ACTBL2interactor150.28686.133Actin (PF00022, IPR004000, SM00268): Actin
10 ACTG1protein found in more fusions430.1721004.149Actin (PF00022, IPR004000, SM00268): Actin
11 ACTN4interactor270.279266.597CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
EFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand
Spectrin (PF00435, IPR002017): Spectrin repeat
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
Uds1 (PF15456, IPR029191): Up-regulated During Septation
12 ADI1interactor40.6671.280ARD (PF03079, IPR004313): ARD/ARD' family
13 ADRB2interactor90.286118.9907tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
14 AHSA1interactor160.60817.076Aha1_N (PF09229, IPR015310, SM01000): Activator of Hsp90 ATPase, N-terminal
AHSA1 (PF08327, IPR013538): Activator of Hsp90 ATPase homolog 1-like protein
15 AKT1oncoprotein240.221448.007PH (PF00169, IPR001849, SM00233): PH domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
16 ALDOBoncoprotein21.0000Glycolytic (PF00274, IPR000741): Fructose-bisphosphate aldolase class-I
17 ALDOCinteractor350.175583.788Glycolytic (PF00274, IPR000741): Fructose-bisphosphate aldolase class-I
18 AMOToncoprotein50.16716.467FAP (PF07174, IPR010801): Fibronectin-attachment protein (FAP)
Gastrin (PF00918, IPR001651, SM00029): Gastrin/cholecystokinin family
DUF2162 (PF09930, IPR017199): Predicted transporter (DUF2162)
Angiomotin_C (PF12240, IPR024646): Angiomotin C terminal
SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
19 ANXA8interactor100Annexin (PF00191, IPR018502, SM00335): Annexin
20 APC2oncoprotein100APC_basic (PF05956, IPR009234): APC basic domain
APC_r (PF05923): APC repeat
Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
SAMP (PF05924, IPR009224): SAMP Motif
Suppressor_APC (PF11414, IPR026831): Adenomatous polyposis coli tumour suppressor protein
Snapin_Pallidin (PF14712, IPR028119): Snapin/Pallidin
Arm_APC_u3 (PF16629): Armadillo-associated region on APC
APC_N_CC (PF16689, IPR032038): Coiled-coil N-terminus of APC, dimerisation domain
21 ARHGDIAinteractor180.294119.055Rho_GDI (PF02115, IPR000406): RHO protein GDP dissociation inhibitor
22 ARRB1interactor190.327100.957Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain
Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain
23 ASS1suppressor130.33366.100Arginosuc_synth (PF00764, IPR001518): Arginosuccinate synthase
24 ATF2oncoprotein280.222268.596bZIP_1 (PF00170, IPR004827): bZIP transcription factor
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
25 ATP5Jinteractor50.6002.767ATP-synt_F6 (PF05511, IPR008387): Mitochondrial ATP synthase coupling factor 6
26 ATP6V1E1interactor50.40010.717vATP-synt_E (PF01991, IPR002842): ATP synthase (E/31 kDa) subunit
27 BCAT2protein found in more fusions200Aminotran_4 (PF01063, IPR001544): Amino-transferase class IV
28 BIN1suppressor6054.785BAR (PF03114, IPR004148, SM00721): BAR domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
29 BRK1interactor60.66710.527DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
30 BTKsuppressor90.35719.189BTK (PF00779, IPR001562, SM00107): BTK motif
PH (PF00169, IPR001849, SM00233): PH domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
31 CACNA1Aprotein found in more fusions100Ca_chan_IQ (PF08763, IPR014873, SM01062): Voltage gated calcium channel IQ domain
GRP (PF07172, IPR010800): Glycine rich protein family
Ion_trans (PF00520, IPR005821): Ion transport protein
Roughex (PF06020, IPR009259): Drosophila roughex protein
SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region
GPHH (PF16905, IPR031649): Voltage-dependent L-type calcium channel, IQ-associated
32 CAPZA2interactor220.390126.519F-actin_cap_A (PF01267, IPR002189): F-actin capping protein alpha subunit
33 CBLsuppressor160.39067.043Cbl_N (PF02262, IPR003153): CBL proto-oncogene N-terminal domain 1
Cbl_N2 (PF02761, IPR014741): CBL proto-oncogene N-terminus, EF hand-like domain
Cbl_N3 (PF02762, IPR014742): CBL proto-oncogene N-terminus, SH2-like domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain
34 CCT2interactor270.410123.091Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
35 CCT4interactor230.39198.626Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
36 CCT5interactor220.372125.886Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
37 CDH2interactor21.0000Cadherin_C (PF01049, IPR000233): Cadherin cytoplasmic region
Cadherin_pro (PF08758, IPR014868, SM01055): Cadherin prodomain like
Cadherin (PF00028, IPR002126, SM00112): Cadherin domain
EphA2_TM (PF14575, IPR027936): Ephrin type-A receptor 2 transmembrane domain
Cadherin_3 (PF16184): Cadherin-like
38 CDK2suppressor490.2711114.224Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family
Pkinase (PF00069, IPR000719): Protein kinase domain
39 CDK2AP1suppressor40.16712.646CDK2AP (PF09806, IPR019187): Cyclin-dependent kinase 2-associated protein
40 CDKN2Asuppressor220.303244.690Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
41 CEP57interactor70.19049.828Cep57_MT_bd (PF06657, IPR024957): Centrosome microtubule-binding domain of Cep57
Tup_N (PF08581, IPR013890): Tup N-terminal
CENP-Q (PF13094, IPR025212): CENP-Q, a CENPA-CAD centromere complex subunit
Cep57_CLD (PF14073, IPR025913): Centrosome localisation domain of Cep57
TRIQK (PF15168, IPR024842): Triple QxxK/R motif-containing protein family
42 CFL1interactor370.356468.070Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein
43 CKBinteractor250.227225.825ATP-gua_Ptrans (PF00217, IPR022414): ATP:guanido phosphotransferase, C-terminal catalytic domain
ATP-gua_PtransN (PF02807, IPR022413): ATP:guanido phosphotransferase, N-terminal domain
44 CKMT1Ainteractor80.28630.328ATP-gua_Ptrans (PF00217, IPR022414): ATP:guanido phosphotransferase, C-terminal catalytic domain
ATP-gua_PtransN (PF02807, IPR022413): ATP:guanido phosphotransferase, N-terminal domain
45 CKMT1Binteractor90.27835.496ATP-gua_Ptrans (PF00217, IPR022414): ATP:guanido phosphotransferase, C-terminal catalytic domain
ATP-gua_PtransN (PF02807, IPR022413): ATP:guanido phosphotransferase, N-terminal domain
46 CKMT2interactor40.5001.395ATP-gua_Ptrans (PF00217, IPR022414): ATP:guanido phosphotransferase, C-terminal catalytic domain
ATP-gua_PtransN (PF02807, IPR022413): ATP:guanido phosphotransferase, N-terminal domain
47 CNN1suppressor30.33322.666Calponin (PF00402, IPR000557): Calponin family repeat
CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
48 COTL1oncoprotein90.52853.216Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein
49 COX4I1interactor50.30021.376COX4 (PF02936, IPR004203): Cytochrome c oxidase subunit IV
50 CSinteractor90.47213.846Citrate_synt (PF00285, IPR002020): Citrate synthase, C-terminal domain
51 CSNK1A1suppressor80.35725.234Pkinase (PF00069, IPR000719): Protein kinase domain
52 CTNNBL1protein found in more fusions308.330Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
DASH_Dad4 (PF08650, IPR013959): DASH complex subunit Dad4
CTNNBL (PF08216, IPR013180, SM01156): Catenin-beta-like, Arm-motif containing nuclear
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
53 CUL1suppressor280.376279.379Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
54 CUL2suppressor210.429230.468Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
55 CUL3protein found in more fusions470.2191006.200Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
56 CUL4Boncoprotein210.51973.932Cullin (PF00888, IPR001373, SM00182): Cullin family
EBP50_C (PF09007, IPR015098): EBP50, C-terminal
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
PG_binding_4 (PF12229, IPR022029): Putative peptidoglycan binding domain
MDFI (PF15316, IPR026134): MyoD family inhibitor
57 CUL7protein found in more fusions350.237482.650ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10)
Cullin (PF00888, IPR001373, SM00182): Cullin family
DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918)
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7
58 DHX9oncoprotein230.289185.076DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold
T2SSE (PF00437, IPR001482): Type II/IV secretion system protein
HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2)
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
59 DMAP1interactor100.55638.971DMAP1 (PF05499, IPR008468): DNA methyltransferase 1-associated protein 1 (DMAP1)
SANT_DAMP1_like (PF16282, IPR032563): SANT/Myb-like domain of DAMP1
60 DMC1interactor307.703Rad51 (PF08423, IPR013632): Rad51
HHH_5 (PF14520): Helix-hairpin-helix domain
61 DMDsuppressor50.4009.112CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
EF-hand_2 (PF09068, IPR015153): EF hand
EF-hand_3 (PF09069, IPR015154): EF-hand
FliD_N (PF02465, IPR003481): Flagellar hook-associated protein 2 N-terminus
IncA (PF04156, IPR007285): IncA protein
Spectrin (PF00435, IPR002017): Spectrin repeat
WW (PF00397, IPR001202, SM00456): WW domain
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
DinB_2 (PF12867, IPR024775): DinB superfamily
CCDC-167 (PF15188, IPR028194): Coiled-coil domain-containing protein 167
62 DNASE1interactor100Exo_endo_phos (PF03372, IPR005135): Endonuclease/Exonuclease/phosphatase family
63 DNMBPinteractor30.6671.125BAR (PF03114, IPR004148, SM00721): BAR domain
HR1 (PF02185, IPR011072, SM00742): Hr1 repeat
IncA (PF04156, IPR007285): IncA protein
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
SH3_2 (PF07653, IPR011511): Variant SH3 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
64 DRC1interactor100GvpK (PF05121, IPR007805): Gas vesicle protein K
Octopine_DH (PF02317, IPR003421): NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain
ApoO (PF09769, IPR019166): Apolipoprotein O
NYD-SP28 (PF14772): Sperm tail
NYD-SP28_assoc (PF14775, IPR029440): Sperm tail C-terminal domain
LRR19-TM (PF15176): Leucine-rich repeat family 19 TM domain
65 DSTNinteractor130.47447.024Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein
66 DUTinteractor180.40596.605dUTPase (PF00692, IPR008180): dUTPase
67 DVL1P1interactor100NA
68 ECHS1protein found in more fusions90.32137.332ECH_1 (PF00378, IPR001753): Enoyl-CoA hydratase/isomerase
69 EGFRoncoprotein380.189866.142Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT)
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
70 ENO1oncoprotein490.244836.984Enolase_C (PF00113, IPR020810): Enolase, C-terminal TIM barrel domain
Enolase_N (PF03952, IPR020811): Enolase, N-terminal domain
71 EP300oncoprotein210.258192.456Creb_binding (PF09030, IPR014744): Creb binding
DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902)
Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
KIX (PF02172, IPR003101): KIX domain
RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6
TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2)
zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger
HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
72 ERBB3oncoprotein120.45534.321Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
73 ERRFI1suppressor70.6006.091GTPase_binding (PF09027, IPR015116): GTPase binding
Inhibitor_Mig-6 (PF11555, IPR021619): EGFR receptor inhibitor Mig-6
74 ETV6suppressor31.0000Ets (PF00178, IPR000418, SM00413): Ets-domain
SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain
75 FABP5interactor130.42384.525Lipocalin (PF00061, IPR000566): Lipocalin / cytosolic fatty-acid binding protein family
76 FANCAoncoprotein70.5335.878Fanconi_A (PF03511, IPR003516): Fanconi anaemia group A protein
Fanconi_A_N (PF15865, IPR031729): Fanconi anaemia group A protein N terminus
77 FHsuppressor130.48730.861Lyase_1 (PF00206, IPR022761): Lyase
FumaraseC_C (PF10415, IPR018951): Fumarase C C-terminus
78 FKBP2interactor100.57824.442FKBP_C (PF00254, IPR001179): FKBP-type peptidyl-prolyl cis-trans isomerase
79 FKBP7interactor70.47618.069FKBP_C (PF00254, IPR001179): FKBP-type peptidyl-prolyl cis-trans isomerase
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
80 FN1oncoprotein390.291321.174fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain
fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
81 FOXRED2interactor100Pyr_redox_3 (PF13738): Pyridine nucleotide-disulphide oxidoreductase
82 FSCN1oncoprotein120.242166.961Fascin (PF06268, IPR022768): Fascin domain
83 FUSsuppressor350.437220.464Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
Limkain-b1 (PF11608, IPR024582): Limkain b1
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
Keratin_2_head (PF16208, IPR032444): Keratin type II head
84 GALNT6interactor100Glyco_transf_7C (PF02709, IPR027791): N-terminal domain of galactosyltransferase
Glycos_transf_2 (PF00535, IPR001173): Glycosyl transferase family 2
Ricin_B_lectin (PF00652, IPR000772, SM00458): Ricin-type beta-trefoil lectin domain
85 GAPDHoncoprotein520.2521018.356Gp_dh_C (PF02800, IPR020829): Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
Gp_dh_N (PF00044, IPR020828, SM00846): Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
OstA (PF03968, IPR005653): OstA-like protein
86 GCprotein found in more fusions200VitD-bind_III (PF09164, IPR015247): Vitamin D binding protein, domain III
Serum_albumin (PF00273, IPR014760, SM00103): Serum albumin family
87 GLO1interactor100.37822.742Glyoxalase (PF00903, IPR004360): Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
88 GPD1Linteractor80.46412.085NAD_Gly3P_dh_C (PF07479, IPR006109): NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
NAD_Gly3P_dh_N (PF01210, IPR011128): NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus
89 GPX4interactor120.60613.148GSHPx (PF00255, IPR000889): Glutathione peroxidase
90 GSNsuppressor130.50036.133Gelsolin (PF00626, IPR007123): Gelsolin repeat
91 H2AFXsuppressor190.351128.912Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
92 HDAC1suppressor280.214431.959FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide
Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
93 HDAC4oncoprotein60.50010.526Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein
Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
94 HDAC5protein found in more fusions290.267210.639Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
NOA36 (PF06524, IPR010531): NOA36 protein
Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3
HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
95 HDAC8interactor201.855DNase-RNase (PF02577, IPR003729): Bifunctional nuclease
Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
96 HNRNPA1interactor400.374343.356RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1
97 HSD17B10interactor280.294318.786adh_short (PF00106, IPR002198): short chain dehydrogenase
98 HSP90AA1oncoprotein570.2161459.587HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
99 HSP90AB1oncoprotein450.323456.112HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
100 HSPB2interactor110.267222.830Crystallin (PF00525, IPR003090): Alpha crystallin A chain, N terminal
HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family
101 HSPD1suppressor330.288266.233Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
102 HSPE1interactor300.234340.387Cpn10 (PF00166, IPR020818, SM00883): Chaperonin 10 Kd subunit
103 HTRA2suppressor70.20045.587Peptidase_S32 (PF05579, IPR008760): Equine arteritis virus serine endopeptidase S32
PDZ_2 (PF13180, IPR001478): PDZ domain
Trypsin_2 (PF13365): Trypsin-like peptidase domain
104 HUWE1oncoprotein350.332259.936BUD22 (PF09073, IPR015158): BUD22
DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908)
DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913)
FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation
HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family
Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm
Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM)
Mucin (PF01456, IPR000458): Mucin-like glycoprotein
Nop14 (PF04147, IPR007276): Nop14-like family
PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
WWE (PF02825, IPR004170, SM00678): WWE domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54
U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414)
105 IFNA4interactor100Interferon (PF00143, IPR000471, SM00076): Interferon alpha/beta domain
106 IMPA2interactor90.50011.635Inositol_P (PF00459, IPR000760): Inositol monophosphatase family
107 IQCB1interactor120.34837.512DUF1765 (PF08578, IPR013887): Protein of unknown function (DUF1765)
IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
HJURP_C (PF12347, IPR022102): Holliday junction regulator protein family C-terminal repeat
Condensin2nSMC (PF12422, IPR024741): Condensin II non structural maintenance of chromosomes subunit
108 ISG15suppressor200.321147.603ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
109 ISYNA1interactor80.6436.361NAD_binding_5 (PF07994, IPR002587): Myo-inositol-1-phosphate synthase
110 ITGA4interactor300.372155.246FG-GAP (PF01839, IPR013517): FG-GAP repeat
Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region
Integrin_alpha2 (PF08441, IPR013649): Integrin alpha
111 KAT5suppressor210.342269.111MOZ_SAS (PF01853, IPR002717): MOZ/SAS family
Tudor-knot (PF11717, IPR025995): RNA binding activity-knot of a chromodomain
112 KCNAB2protein found in more fusions31.0000Aldo_ket_red (PF00248, IPR023210): Aldo/keto reductase family
113 KLHL20interactor302.868BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
114 LDHAinteractor350.399193.548Ldh_1_C (PF02866, IPR022383): lactate/malate dehydrogenase, alpha/beta C-terminal domain
Ldh_1_N (PF00056, IPR001236): lactate/malate dehydrogenase, NAD binding domain
115 LGALS1interactor130.32152.830Gal-bind_lectin (PF00337, IPR001079, SM00908): Galactoside-binding lectin
116 LGALS3oncoprotein90.32171.372Gal-bind_lectin (PF00337, IPR001079, SM00908): Galactoside-binding lectin
117 LIG4interactor70.5248.402APG17 (PF04108, IPR007240): Autophagy protein Apg17
BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
DNA_ligase_A_C (PF04679, IPR012309): ATP dependent DNA ligase C terminal region
DNA_ligase_A_M (PF01068, IPR012310): ATP dependent DNA ligase domain
DNA_ligase_A_N (PF04675, IPR012308): DNA ligase N terminus
DNA_ligase_IV (PF11411, IPR021536): DNA ligase IV
RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain
118 LIMA1suppressor230.435132.670LIM (PF00412, IPR001781, SM00132): LIM domain
ROKNT (PF08067, IPR012987): ROKNT (NUC014) domain
119 LMAN1interactor50.6003.429Lectin_leg-like (PF03388, IPR005052): Legume-like lectin family
Golgin_A5 (PF09787, IPR019177): Golgin subfamily A member 5
KxDL (PF10241, IPR019371): Uncharacterized conserved protein
DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404)
120 LRCH3interactor50.6005.153CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
LRR_8 (PF13855, IPR001611): Leucine rich repeat
121 LTA4Hinteractor60.5335.630Leuk-A4-hydro_C (PF09127, IPR015211): Leukotriene A4 hydrolase, C-terminal
Peptidase_M1 (PF01433, IPR014782): Peptidase family M1
122 MAP2K7interactor50.50010.467Pkinase (PF00069, IPR000719): Protein kinase domain
123 MAPK14oncoprotein180.213198.521Pkinase (PF00069, IPR000719): Protein kinase domain
124 MARK4oncoprotein31.0000KA1 (PF02149, IPR001772): Kinase associated domain 1
Pkinase (PF00069, IPR000719): Protein kinase domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
125 MCM2oncoprotein510.308906.942AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA)
MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
126 MIB2oncoprotein208.330Ank (PF00023, IPR002110, SM00248): Ankyrin repeat
KOW (PF00467, IPR005824, SM00739): KOW motif
MIB_HERC2 (PF06701, IPR010606): Mib_herc2
TPR_4 (PF07721, IPR011717): Tetratricopeptide repeat
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
127 MLH1suppressor130.244165.810DNA_mis_repair (PF01119, IPR013507): DNA mismatch repair protein, C-terminal domain
HATPase_c_3 (PF13589): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
Mlh1_C (PF16413, IPR032189): DNA mismatch repair protein Mlh1 C-terminus
128 MLPHinteractor206.896Dpy-30 (PF05186, IPR007858): Dpy-30 motif
Rab_eff_C (PF04698, IPR006788): Rab effector MyRIP/melanophilin C-terminus
FYVE_2 (PF02318, IPR010911): FYVE-type zinc finger
RIC3 (PF15361, IPR032763): Resistance to inhibitors of cholinesterase homologue 3
129 MORF4L1interactor90.7864.776MRG (PF05712, IPR026541): MRG
Fmp27_WPPW (PF10359, IPR019449): RNA pol II promoter Fmp27 protein domain
Tudor-knot (PF11717, IPR025995): RNA binding activity-knot of a chromodomain
130 MORF4L2interactor70.9051.763MRG (PF05712, IPR026541): MRG
131 MRGBPinteractor61.0000Eaf7 (PF07904, IPR012423): Chromatin modification-related protein EAF7
132 MYConcoprotein310.234439.262HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain
Myc_N (PF01056, IPR012682): Myc amino-terminal region
133 MYH7Binteractor60.8002.708Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain
Myosin_tail_1 (PF01576, IPR002928): Myosin tail
YkuI_C (PF10388, IPR018842): EAL-domain associated signalling protein domain
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
134 MYH9suppressor400.281520.814IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain
Myosin_tail_1 (PF01576, IPR002928): Myosin tail
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
135 MYO18Ainteractor200.447109.967Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1
IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_tail_1 (PF01576, IPR002928): Myosin tail
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2
136 MYO1Cinteractor240.388164.068IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_TH1 (PF06017, IPR010926): Unconventional myosin tail, actin- and lipid-binding
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
137 MYOCinteractor100.50028.422IncA (PF04156, IPR007285): IncA protein
OLF (PF02191, IPR003112, SM00284): Olfactomedin-like domain
138 NCAPHinteractor31.0000Cnd2 (PF05786, IPR022816): Condensin complex subunit 2
139 NCKAP1interactor70.47657.892Nckap1 (PF09735, IPR019137): Membrane-associated apoptosis protein
140 NCOA3oncoprotein90.27824.727DUF1518 (PF07469, IPR010011, SM01151): Domain of unknown function (DUF1518)
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
Nuc_rec_co-act (PF08815, IPR014920): Nuclear receptor coactivator
PAS (PF00989, IPR013767, SM00091): PAS fold
PAS_3 (PF08447, IPR013655): PAS fold
Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region
SRC-1 (PF08832, IPR014935): Steroid receptor coactivator
PAS_11 (PF14598): PAS domain
DUF4927 (PF16279, IPR032565): Domain of unknown function (DUF4927)
NCOA_u2 (PF16665): Unstructured region on nuclear receptor coactivator protein
AIM3 (PF17096, IPR031370): Altered inheritance of mitochondria protein 3
141 NCSTNinteractor50.10069.513Nicastrin (PF05450, IPR008710): Nicastrin
Ost4 (PF10215, IPR018943): Oligosaccaryltransferase
142 NDUFS4interactor30.6670.667ETC_C1_NDUFA4 (PF04800, IPR006885): ETC complex I subunit conserved region
143 NRAPinteractor21.0000LIM (PF00412, IPR001781, SM00132): LIM domain
Nebulin (PF00880, IPR000900, SM00227): Nebulin repeat
144 NTRK1oncoprotein770.1693838.103I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
145 OBSL1interactor280.293271.656BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain
Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
146 OSBPL10interactor201.388Flagellar_rod (PF05149, IPR007824): Paraflagellar rod protein
Oxysterol_BP (PF01237, IPR000648): Oxysterol-binding protein
PH_8 (PF15409): Pleckstrin homology domain
147 PCNAoncoprotein310.326237.163PCNA_C (PF02747, IPR022649): Proliferating cell nuclear antigen, C-terminal domain
PCNA_N (PF00705, IPR022648): Proliferating cell nuclear antigen, N-terminal domain
148 PCYT1Binteractor100ApoC-I (PF04691, IPR006781): Apolipoprotein C-I (ApoC-1)
CTP_transf_like (PF01467, IPR004821): Cytidylyltransferase-like
FTO_CTD (PF12934, IPR024366): FTO C-terminal domain
149 PFDN1interactor21.0000Prefoldin_2 (PF01920, IPR002777): Prefoldin subunit
150 PGAM2interactor40.5001.420His_Phos_1 (PF00300, IPR013078, SM00855): Histidine phosphatase superfamily (branch 1)
151 PGK1interactor300.421281.830PGK (PF00162, IPR001576): Phosphoglycerate kinase
152 PHACTR1interactor21.0000BAF1_ABF1 (PF04684, IPR006774): BAF1 / ABF1 chromatin reorganising factor
FAP (PF07174, IPR010801): Fibronectin-attachment protein (FAP)
RPEL (PF02755, IPR004018, SM00707): RPEL repeat
153 PIAS4interactor40.6677.008CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain
SAP (PF02037, IPR003034, SM00513): SAP domain
zf-MIZ (PF02891, IPR004181): MIZ/SP-RING zinc finger
PINIT (PF14324, IPR023321): PINIT domain
154 PKMoncoprotein400.329328.312PK (PF00224, IPR015793): Pyruvate kinase, barrel domain
PK_C (PF02887, IPR015795): Pyruvate kinase, alpha/beta domain
155 PLD2interactor70.28658.071PH (PF00169, IPR001849, SM00233): PH domain
PLDc (PF00614, IPR001736, SM00155): Phospholipase D Active site motif
PX (PF00787, IPR001683, SM00312): PX domain
PLDc_2 (PF13091, IPR025202): PLD-like domain
156 POLR1Binteractor40.8335.592RNA_pol_Rpa2_4 (PF06883, IPR009674): RNA polymerase I, Rpa2 specific domain
RNA_pol_Rpb2_1 (PF04563, IPR007644): RNA polymerase beta subunit
RNA_pol_Rpb2_3 (PF04565, IPR007645): RNA polymerase Rpb2, domain 3
RNA_pol_Rpb2_6 (PF00562, IPR007120): RNA polymerase Rpb2, domain 6
RNA_pol_Rpb2_7 (PF04560, IPR007641): RNA polymerase Rpb2, domain 7
157 POU5F1oncoprotein120.127222.681Pou (PF00157, IPR000327, SM00352): Pou domain - N-terminal to homeobox domain
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
158 PPP1CAsuppressor260.308251.736Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
159 PPP1CBinteractor220.45994.027Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
160 PPP1R1Aoncoprotein100DARPP-32 (PF05395, IPR008466): Protein phosphatase inhibitor 1/DARPP-32
161 PPP1R9Binteractor90.55613.373PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
Stm1_N (PF09598, IPR019084): Stm1
TSC22 (PF01166, IPR000580): TSC-22/dip/bun family
DUF2968 (PF11180, IPR021350): Protein of unknown function (DUF2968)
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
PRIMA1 (PF16101): Proline-rich membrane anchor 1
NuDC (PF16273, IPR032572): Nuclear distribution C domain
162 PREPinteractor70.52424.667Peptidase_S9 (PF00326, IPR001375): Prolyl oligopeptidase family
Peptidase_S9_N (PF02897, IPR023302): Prolyl oligopeptidase, N-terminal beta-propeller domain
163 PRKCEsuppressor90.46417.064C2 (PF00168, IPR000008, SM00239): C2 domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
164 PSMA3protein found in more fusions260.417244.775Proteasome (PF00227, IPR001353): Proteasome subunit
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
165 PSMD4interactor150.229130.807UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
VWA_2 (PF13519, IPR002035): von Willebrand factor type A domain
166 PTPN22interactor50.33313.543Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase
167 RAD52oncoprotein70.5331.471Rad52_Rad22 (PF04098, IPR007232): Rad52/22 family double-strand break repair protein
DUF2335 (PF10097, IPR019284): Predicted membrane protein (DUF2335)
168 RELAoncoprotein160.36281.449DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain
RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
169 RPS6KB1interactor70.40029.526Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
170 RPS6KB2interactor170.30154.252Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
171 RRN3interactor40.8331.126RRN3 (PF05327, IPR007991): RNA polymerase I specific transcription initiation factor RRN3
172 SCINinteractor21.0000Gelsolin (PF00626, IPR007123): Gelsolin repeat
173 SFNsuppressor150.29776.10914-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
174 SHC1oncoprotein180.42693.021PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID)
SH2 (PF00017, IPR000980, SM00252): SH2 domain
175 SMARCB1suppressor100.38948.683SNF5 (PF04855, IPR006939): SNF5 / SMARCB1 / INI1
176 SMARCD1interactor40.6672.807ATP-synt_G (PF04718, IPR006808): Mitochondrial ATP synthase g subunit
DivIC (PF04977, IPR007060): Septum formation initiator
SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain
177 SNCAinteractor90.57115.765Synuclein (PF01387, IPR001058): Synuclein
178 SOD2suppressor100.41723.111Sod_Fe_C (PF02777, IPR019832): Iron/manganese superoxide dismutases, C-terminal domain
Sod_Fe_N (PF00081, IPR019831): Iron/manganese superoxide dismutases, alpha-hairpin domain
179 SPTAN1oncoprotein250.343203.111EFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand
Spectrin (PF00435, IPR002017): Spectrin repeat
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
Tetrabrachion (PF11401, IPR021535): Tetrabrachion
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
E2F_CC-MB (PF16421, IPR032198): E2F transcription factor CC-MB domain
180 SRPK2oncoprotein120.218287.710DUF1387 (PF07139, IPR009816): Protein of unknown function (DUF1387)
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
Pkinase (PF00069, IPR000719): Protein kinase domain
S-antigen (PF05756, IPR008825): S-antigen protein
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
181 SUMO2interactor100.25045.623Rad60-SLD (PF11976, IPR022617): Ubiquitin-2 like Rad60 SUMO-like
182 SUMO4interactor31.0000SRP9-21 (PF05486): Signal recognition particle 9 kDa protein (SRP9)
Rad60-SLD (PF11976, IPR022617): Ubiquitin-2 like Rad60 SUMO-like
183 SUZ12suppressor140.167145.921DUF2070 (PF09843, IPR019204): Predicted membrane protein (DUF2070)
VEFS-Box (PF09733, IPR019135): VEFS-Box of polycomb protein
184 TAGLNsuppressor120.515225.473Calponin (PF00402, IPR000557): Calponin family repeat
CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
185 TAGLN2interactor250.360131.236Calponin (PF00402, IPR000557): Calponin family repeat
CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
186 TALDO1interactor120.45536.481TAL_FSA (PF00923, IPR001585): Transaldolase/Fructose-6-phosphate aldolase
187 TERF1interactor200.316234.874TRF (PF08558, IPR013867): Telomere repeat binding factor (TRF)
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
188 TESsuppressor61.0000LIM (PF00412, IPR001781, SM00132): LIM domain
PET (PF06297, IPR010442): PET Domain
PSCyt3 (PF07627, IPR013039): Protein of unknown function (DUF1588)
Ig_Tie2_1 (PF10430, IPR018941): Tie-2 Ig-like domain 1
189 TKTprotein found in more fusions350.337281.512Transket_pyr (PF02779, IPR005475, SM00861): Transketolase, pyrimidine binding domain
Transketolase_C (PF02780, IPR005476): Transketolase, C-terminal domain
Transketolase_N (PF00456, IPR005474): Transketolase, thiamine diphosphate binding domain
190 TMSB4Xinteractor40.50013.547Thymosin (PF01290, IPR001152, SM00152): Thymosin beta-4 family
191 TMSB4Yinteractor207.257Thymosin (PF01290, IPR001152, SM00152): Thymosin beta-4 family
192 TNNI3Kinteractor201.855Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
193 TNPO3interactor40.6679.264HEAT (PF02985, IPR000357): HEAT repeat
IFRD (PF05004, IPR007701): Interferon-related developmental regulator (IFRD)
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
194 TPM2protein found in more fusions130.379229.369DASH_Spc19 (PF08287, IPR013251): Spc19
Tropomyosin (PF00261, IPR000533): Tropomyosin
Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like
195 TRAF3IP1interactor110.30960.495MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
196 TRAP1oncoprotein150.39048.392HSP90 (PF00183, IPR001404): Hsp90 protein
HATPase_c_3 (PF13589): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
197 TRIM55interactor50.33324.359Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein
NABP (PF07990, IPR012940): Nucleic acid binding protein NABP
zf-HIT (PF04438, IPR007529): HIT zinc finger
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
198 TRIM63interactor110.200255.233DUF349 (PF03993, IPR007139): Domain of Unknown Function (DUF349)
KIP1 (PF07765, IPR011684): KIP1-like protein
RED_C (PF07807, IPR012492): RED-like protein C-terminal region
zf-HIT (PF04438, IPR007529): HIT zinc finger
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
YceG_bac (PF14266, IPR025647): Putative component of 'biosynthetic module'
199 TRIP6interactor40.16724.866DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
LIM (PF00412, IPR001781, SM00132): LIM domain
200 TSC1suppressor41.0000Bcr-Abl_Oligo (PF09036, IPR015123): Bcr-Abl oncoprotein oligomerisation domain
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
Hamartin (PF04388, IPR007483): Hamartin protein
201 UBAC2interactor100Rhomboid (PF01694, IPR022764): Rhomboid family
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
202 UBE3Aoncoprotein100.33386.852HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
PCM1_C (PF15717, IPR031446): Pericentriolar material 1 C terminus
AZUL (PF16558, IPR032353): Amino-terminal Zinc-binding domain of ubiquitin ligase E3A
203 UBL4Ainteractor110.273143.264ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
204 UMPSinteractor60.5339.566OMPdecase (PF00215, IPR001754, SM00934): Orotidine 5'-phosphate decarboxylase / HUMPS family
Pribosyltran (PF00156, IPR000836): Phosphoribosyl transferase domain
205 USP15oncoprotein130.33363.655UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
DUSP (PF06337, IPR006615, SM00695): DUSP domain
Ubiquitin_3 (PF14836, IPR028135): Ubiquitin-like domain
206 USP25protein found in more fusions60.30030.870UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
UCH_1 (PF13423, IPR001394): Ubiquitin carboxyl-terminal hydrolase
UBA_4 (PF14555): UBA-like domain
207 VCAM1interactor280.336137.283C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
208 VCPKMTinteractor100Methyltransf_16 (PF10294, IPR019410): Lysine methyltransferase
209 VIMsuppressor230.195249.702Filament (PF00038, IPR001664): Intermediate filament protein
Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region
210 VPS18interactor50.30024.905Pep3_Vps18 (PF05131, IPR007810): Pep3/Vps18/deep orange family
Clathrin (PF00637, IPR000547, SM00299): Region in Clathrin and VPS
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
211 XPO6interactor203.451IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
212 XRN1interactor70.6194.566XRN_N (PF03159, IPR004859): XRN 5'-3' exonuclease N-terminus

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