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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)121
The number (and %) of the onco-proteins29 (23.97 %)
The number (and %) of the tumor suppressors15 (12.40 %)
Total number of binary PPIs (saturation %)862 (11.87 %)
The number (and %) of affected PPIs121 (14.04 %)
The number of possible different fusions20
PPI diameter3
PPI radius2
The average degree of PPI13.570
Assortativity coefficient-0.1404
The network average Clustering coefficient0.444
The number (and %) of a zero Clustering coefficients8 (6.61 %)
The number (and %) of a zero Betweenness Centrality10 (8.26 %)

ACTIVE INTERACTORS


List of the fusions

Proteins found in more fusions APP (see 4 fusions); FUS/PKM (see 1 fusions); SOD2 (see 3 fusions); TKT (see 5 fusions); HSP90AA1 (see 3 fusions); HUWE1 (see 2 fusions); CUL3 (see 1 fusions); HSP90AB1 (see 1 fusions); SRPK2 (see 1 fusions); MYC (see 2 fusions); EGFR (see 2 fusions); MCM2 (see 1 fusions); FANCA (see 1 fusions); HDAC5 (see 1 fusions); ECHS1 (see 1 fusions); PCNA (see 1 fusions); KCNAB2 (see 1 fusions); GAPDH (see 3 fusions); SUZ12 (see 2 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 ALDOAparental protein1080.1106955.680Glycolytic (PF00274, IPR000741): Fructose-bisphosphate aldolase class-I
2 DHRS7Bparental protein130.090343.971adh_short (PF00106, IPR002198): short chain dehydrogenase
3 ACAA2interactor160.42563.804Thiolase_C (PF02803, IPR020617): Thiolase, C-terminal domain
Thiolase_N (PF00108, IPR020616): Thiolase, N-terminal domain
4 ACIN1interactor60.40027.768Calc_CGRP_IAPP (PF00214, IPR021116): Calcitonin / CGRP / IAPP family
CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain
DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755)
OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain
Pinin_SDK_memA (PF04696, IPR006786): pinin/SDK/memA/ protein conserved region
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SAP (PF02037, IPR003034, SM00513): SAP domain
V_ATPase_I (PF01496, IPR002490): V-type ATPase 116kDa subunit family
FAM27 (PF15832, IPR031672): FAM27 D and E protein family
DUF4746 (PF15928, IPR031827): Domain of unknown function (DUF4746)
RSB_motif (PF16294, IPR032552): RNSP1-SAP18 binding (RSB) motif
SWIRM-assoc_2 (PF16496, IPR032450): SWIRM-associated domain at the N-terminal
5 ACO2interactor130.32152.162Aconitase (PF00330, IPR001030): Aconitase family (aconitate hydratase)
Aconitase_C (PF00694, IPR000573): Aconitase C-terminal domain
6 ACTN4interactor140.41820.518CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
EFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand
Spectrin (PF00435, IPR002017): Spectrin repeat
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
Uds1 (PF15456, IPR029191): Up-regulated During Septation
7 ADI1interactor50.4004.207ARD (PF03079, IPR004313): ARD/ARD' family
8 ADRB2interactor60.7001.0227tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
9 AHSA1interactor150.62928.327Aha1_N (PF09229, IPR015310, SM01000): Activator of Hsp90 ATPase, N-terminal
AHSA1 (PF08327, IPR013538): Activator of Hsp90 ATPase homolog 1-like protein
10 AKT1oncoprotein110.5119.171PH (PF00169, IPR001849, SM00233): PH domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
11 ALDOBoncoprotein30.6670.705Glycolytic (PF00274, IPR000741): Fructose-bisphosphate aldolase class-I
12 ALDOCinteractor360.167481.048Glycolytic (PF00274, IPR000741): Fructose-bisphosphate aldolase class-I
13 APPprotein found in more fusions350.152520.459APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding
Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP)
BUD22 (PF09073, IPR015158): BUD22
IncA (PF04156, IPR007285): IncA protein
Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus
APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
14 ARHGDIAinteractor150.35236.646Rho_GDI (PF02115, IPR000406): RHO protein GDP dissociation inhibitor
15 ASS1suppressor120.45513.464Arginosuc_synth (PF00764, IPR001518): Arginosuccinate synthase
16 ATF2oncoprotein190.38673.276bZIP_1 (PF00170, IPR004827): bZIP transcription factor
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
17 ATP5Jinteractor80.250365.528ATP-synt_F6 (PF05511, IPR008387): Mitochondrial ATP synthase coupling factor 6
18 ATP6V1E1interactor70.33344.458vATP-synt_E (PF01991, IPR002842): ATP synthase (E/31 kDa) subunit
19 BCAT2interactor300.705Aminotran_4 (PF01063, IPR001544): Amino-transferase class IV
20 BREoncoprotein203.886BRE (PF06113, IPR010358): Brain and reproductive organ-expressed protein (BRE)
21 C15orf48interactor30.6672.621B12D (PF06522, IPR010530): NADH-ubiquinone reductase complex 1 MLRQ subunit
22 CACNA1Ainteractor3081.789Ca_chan_IQ (PF08763, IPR014873, SM01062): Voltage gated calcium channel IQ domain
GRP (PF07172, IPR010800): Glycine rich protein family
Ion_trans (PF00520, IPR005821): Ion transport protein
Roughex (PF06020, IPR009259): Drosophila roughex protein
SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region
GPHH (PF16905, IPR031649): Voltage-dependent L-type calcium channel, IQ-associated
23 CDK2suppressor270.46571.029Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family
Pkinase (PF00069, IPR000719): Protein kinase domain
24 CDK2AP1suppressor21.0000CDK2AP (PF09806, IPR019187): Cyclin-dependent kinase 2-associated protein
25 CFL1interactor280.426182.032Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein
26 CKBinteractor200.24776.792ATP-gua_Ptrans (PF00217, IPR022414): ATP:guanido phosphotransferase, C-terminal catalytic domain
ATP-gua_PtransN (PF02807, IPR022413): ATP:guanido phosphotransferase, N-terminal domain
27 CKMT1Ainteractor70.3817.421ATP-gua_Ptrans (PF00217, IPR022414): ATP:guanido phosphotransferase, C-terminal catalytic domain
ATP-gua_PtransN (PF02807, IPR022413): ATP:guanido phosphotransferase, N-terminal domain
28 CKMT1Binteractor90.30633.416ATP-gua_Ptrans (PF00217, IPR022414): ATP:guanido phosphotransferase, C-terminal catalytic domain
ATP-gua_PtransN (PF02807, IPR022413): ATP:guanido phosphotransferase, N-terminal domain
29 CKMT2interactor40.5001.797ATP-gua_Ptrans (PF00217, IPR022414): ATP:guanido phosphotransferase, C-terminal catalytic domain
ATP-gua_PtransN (PF02807, IPR022413): ATP:guanido phosphotransferase, N-terminal domain
30 COQ9interactor40.6672.621COQ9 (PF08511, IPR013718): COQ9
31 COX4I1interactor60.46733.466COX4 (PF02936, IPR004203): Cytochrome c oxidase subunit IV
32 CSinteractor70.6671.451Citrate_synt (PF00285, IPR002020): Citrate synthase, C-terminal domain
33 CUL2suppressor150.66713.241Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
34 CUL3protein found in more fusions320.353176.467Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
35 CUL4Boncoprotein180.66713.723Cullin (PF00888, IPR001373, SM00182): Cullin family
EBP50_C (PF09007, IPR015098): EBP50, C-terminal
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
PG_binding_4 (PF12229, IPR022029): Putative peptidoglycan binding domain
MDFI (PF15316, IPR026134): MyoD family inhibitor
36 DRC1interactor100GvpK (PF05121, IPR007805): Gas vesicle protein K
Octopine_DH (PF02317, IPR003421): NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain
ApoO (PF09769, IPR019166): Apolipoprotein O
NYD-SP28 (PF14772): Sperm tail
NYD-SP28_assoc (PF14775, IPR029440): Sperm tail C-terminal domain
LRR19-TM (PF15176): Leucine-rich repeat family 19 TM domain
37 DUTinteractor170.41967.188dUTPase (PF00692, IPR008180): dUTPase
38 ECHS1protein found in more fusions80.42911.009ECH_1 (PF00378, IPR001753): Enoyl-CoA hydratase/isomerase
39 EGFRoncoprotein240.308222.245Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT)
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
40 ENO1oncoprotein440.272533.582Enolase_C (PF00113, IPR020810): Enolase, C-terminal TIM barrel domain
Enolase_N (PF03952, IPR020811): Enolase, N-terminal domain
41 FABP5interactor110.60021.160Lipocalin (PF00061, IPR000566): Lipocalin / cytosolic fatty-acid binding protein family
42 FANCAoncoprotein60.7000.545Fanconi_A (PF03511, IPR003516): Fanconi anaemia group A protein
Fanconi_A_N (PF15865, IPR031729): Fanconi anaemia group A protein N terminus
43 FHsuppressor130.48719.097Lyase_1 (PF00206, IPR022761): Lyase
FumaraseC_C (PF10415, IPR018951): Fumarase C C-terminus
44 FKBP2interactor90.7224.864FKBP_C (PF00254, IPR001179): FKBP-type peptidyl-prolyl cis-trans isomerase
45 FKBP7interactor60.6675.508FKBP_C (PF00254, IPR001179): FKBP-type peptidyl-prolyl cis-trans isomerase
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
46 FN1oncoprotein270.410122.656fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain
fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
47 FUSsuppressor250.58086.137Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
Limkain-b1 (PF11608, IPR024582): Limkain b1
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
Keratin_2_head (PF16208, IPR032444): Keratin type II head
48 GALNT6interactor100Glyco_transf_7C (PF02709, IPR027791): N-terminal domain of galactosyltransferase
Glycos_transf_2 (PF00535, IPR001173): Glycosyl transferase family 2
Ricin_B_lectin (PF00652, IPR000772, SM00458): Ricin-type beta-trefoil lectin domain
49 GAPDHoncoprotein420.328295.223Gp_dh_C (PF02800, IPR020829): Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
Gp_dh_N (PF00044, IPR020828, SM00846): Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
OstA (PF03968, IPR005653): OstA-like protein
50 GLO1interactor90.44410.285Glyoxalase (PF00903, IPR004360): Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
51 GOLT1Binteractor70.14342.265Got1 (PF04178, IPR007305): Got1/Sft2-like family
52 GPD1Linteractor80.4647.889NAD_Gly3P_dh_C (PF07479, IPR006109): NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
NAD_Gly3P_dh_N (PF01210, IPR011128): NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus
53 GPX4interactor120.60610.539GSHPx (PF00255, IPR000889): Glutathione peroxidase
54 H2AFXsuppressor150.46743.534Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
Histone_H2A_C (PF16211, IPR032454): C-terminus of histone H2A
55 HDAC5protein found in more fusions190.35933.891Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
NOA36 (PF06524, IPR010531): NOA36 protein
Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3
HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
56 HECW2interactor60.10028.576C2 (PF00168, IPR000008, SM00239): C2 domain
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
Cep57_CLD (PF14073, IPR025913): Centrosome localisation domain of Cep57
RFXA_RFXANK_bdg (PF15289, IPR029316): Regulatory factor X-associated C-terminal binding domain
HECW_N (PF16562, IPR032348): N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2
57 HNRNPA1interactor340.413174.924RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1
58 HSD17B10interactor240.38082.782adh_short (PF00106, IPR002198): short chain dehydrogenase
59 HSP90AA1oncoprotein360.351198.311HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
60 HSP90AB1oncoprotein290.50873.301HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
61 HSPB2interactor70.4675.901Crystallin (PF00525, IPR003090): Alpha crystallin A chain, N terminal
HSP20 (PF00011, IPR002068): Hsp20/alpha crystallin family
62 HSPD1suppressor270.353128.967Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
63 HSPE1interactor250.257134.248Cpn10 (PF00166, IPR020818, SM00883): Chaperonin 10 Kd subunit
64 HUWE1oncoprotein250.48243.847BUD22 (PF09073, IPR015158): BUD22
DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908)
DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913)
FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation
HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family
Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm
Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM)
Mucin (PF01456, IPR000458): Mucin-like glycoprotein
Nop14 (PF04147, IPR007276): Nop14-like family
PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
WWE (PF02825, IPR004170, SM00678): WWE domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54
U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414)
65 IFNA4interactor100Interferon (PF00143, IPR000471, SM00076): Interferon alpha/beta domain
66 IMPA2interactor80.6673.071Inositol_P (PF00459, IPR000760): Inositol monophosphatase family
67 IQCB1interactor90.5835.189DUF1765 (PF08578, IPR013887): Protein of unknown function (DUF1765)
IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
HJURP_C (PF12347, IPR022102): Holliday junction regulator protein family C-terminal repeat
Condensin2nSMC (PF12422, IPR024741): Condensin II non structural maintenance of chromosomes subunit
68 ISG15suppressor130.5519.723ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
69 ISYNA1interactor80.6436.362NAD_binding_5 (PF07994, IPR002587): Myo-inositol-1-phosphate synthase
70 ITGA4interactor210.55826.776FG-GAP (PF01839, IPR013517): FG-GAP repeat
Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region
Integrin_alpha2 (PF08441, IPR013649): Integrin alpha
71 KCNAB2protein found in more fusions31.0000Aldo_ket_red (PF00248, IPR023210): Aldo/keto reductase family
72 LDHAinteractor320.432129.629Ldh_1_C (PF02866, IPR022383): lactate/malate dehydrogenase, alpha/beta C-terminal domain
Ldh_1_N (PF00056, IPR001236): lactate/malate dehydrogenase, NAD binding domain
73 LGALS1interactor110.30974.748Gal-bind_lectin (PF00337, IPR001079, SM00908): Galactoside-binding lectin
74 LIG4interactor70.57117.268APG17 (PF04108, IPR007240): Autophagy protein Apg17
BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
DNA_ligase_A_C (PF04679, IPR012309): ATP dependent DNA ligase C terminal region
DNA_ligase_A_M (PF01068, IPR012310): ATP dependent DNA ligase domain
DNA_ligase_A_N (PF04675, IPR012308): DNA ligase N terminus
DNA_ligase_IV (PF11411, IPR021536): DNA ligase IV
RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain
75 LMAN1interactor80.250186.964Lectin_leg-like (PF03388, IPR005052): Legume-like lectin family
Golgin_A5 (PF09787, IPR019177): Golgin subfamily A member 5
KxDL (PF10241, IPR019371): Uncharacterized conserved protein
DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404)
76 LTA4Hinteractor60.5332.779Leuk-A4-hydro_C (PF09127, IPR015211): Leukotriene A4 hydrolase, C-terminal
Peptidase_M1 (PF01433, IPR014782): Peptidase family M1
77 MAP2K7interactor40.8330.286Pkinase (PF00069, IPR000719): Protein kinase domain
78 MCM2oncoprotein340.462103.005AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA)
MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
79 MLH1suppressor80.5006.695DNA_mis_repair (PF01119, IPR013507): DNA mismatch repair protein, C-terminal domain
HATPase_c_3 (PF13589): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
Mlh1_C (PF16413, IPR032189): DNA mismatch repair protein Mlh1 C-terminus
80 MYConcoprotein160.38136.626HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain
Myc_N (PF01056, IPR012682): Myc amino-terminal region
81 MYH7Binteractor60.8001.452Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain
Myosin_tail_1 (PF01576, IPR002928): Myosin tail
YkuI_C (PF10388, IPR018842): EAL-domain associated signalling protein domain
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
82 MYOCinteractor70.9330.091IncA (PF04156, IPR007285): IncA protein
OLF (PF02191, IPR003112, SM00284): Olfactomedin-like domain
83 NCAPHinteractor31.0000Cnd2 (PF05786, IPR022816): Condensin complex subunit 2
84 NCSTNinteractor40.16750.701Nicastrin (PF05450, IPR008710): Nicastrin
Ost4 (PF10215, IPR018943): Oligosaccaryltransferase
85 NDUFS4interactor50.40034.149ETC_C1_NDUFA4 (PF04800, IPR006885): ETC complex I subunit conserved region
86 NTRK1oncoprotein520.232731.643I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
87 OSBPL10interactor100Flagellar_rod (PF05149, IPR007824): Paraflagellar rod protein
Oxysterol_BP (PF01237, IPR000648): Oxysterol-binding protein
PH_8 (PF15409): Pleckstrin homology domain
88 PCNAoncoprotein200.49133.099PCNA_C (PF02747, IPR022649): Proliferating cell nuclear antigen, C-terminal domain
PCNA_N (PF00705, IPR022648): Proliferating cell nuclear antigen, N-terminal domain
89 PGAM2interactor40.5001.175His_Phos_1 (PF00300, IPR013078, SM00855): Histidine phosphatase superfamily (branch 1)
90 PGK1interactor260.51159.836PGK (PF00162, IPR001576): Phosphoglycerate kinase
91 PIAS4interactor30.66710.885CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain
SAP (PF02037, IPR003034, SM00513): SAP domain
zf-MIZ (PF02891, IPR004181): MIZ/SP-RING zinc finger
PINIT (PF14324, IPR023321): PINIT domain
92 PKMoncoprotein320.417120.100PK (PF00224, IPR015793): Pyruvate kinase, barrel domain
PK_C (PF02887, IPR015795): Pyruvate kinase, alpha/beta domain
93 PLD2interactor40.8330.154PH (PF00169, IPR001849, SM00233): PH domain
PLDc (PF00614, IPR001736, SM00155): Phospholipase D Active site motif
PX (PF00787, IPR001683, SM00312): PX domain
PLDc_2 (PF13091, IPR025202): PLD-like domain
94 PREPinteractor70.5249.178Peptidase_S9 (PF00326, IPR001375): Prolyl oligopeptidase family
Peptidase_S9_N (PF02897, IPR023302): Prolyl oligopeptidase, N-terminal beta-propeller domain
95 PSMA3interactor210.52131.146Proteasome (PF00227, IPR001353): Proteasome subunit
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
96 PSMD4interactor100.40017.453UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
VWA_2 (PF13519, IPR002035): von Willebrand factor type A domain
97 RAB1Boncoprotein70.28630.680Ras (PF00071, IPR001806, SM00173): Ras family
98 RAB7Asuppressor90.19490.134Ras (PF00071, IPR001806, SM00173): Ras family
99 RAD52oncoprotein70.5331.262Rad52_Rad22 (PF04098, IPR007232): Rad52/22 family double-strand break repair protein
DUF2335 (PF10097, IPR019284): Predicted membrane protein (DUF2335)
100 SOD2suppressor100.4449.251Sod_Fe_C (PF02777, IPR019832): Iron/manganese superoxide dismutases, C-terminal domain
Sod_Fe_N (PF00081, IPR019831): Iron/manganese superoxide dismutases, alpha-hairpin domain
101 SRPK2oncoprotein80.66712.870DUF1387 (PF07139, IPR009816): Protein of unknown function (DUF1387)
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
Pkinase (PF00069, IPR000719): Protein kinase domain
S-antigen (PF05756, IPR008825): S-antigen protein
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
102 SUMO2interactor80.286183.570Rad60-SLD (PF11976, IPR022617): Ubiquitin-2 like Rad60 SUMO-like
103 SUMO4interactor31.0000SRP9-21 (PF05486): Signal recognition particle 9 kDa protein (SRP9)
Rad60-SLD (PF11976, IPR022617): Ubiquitin-2 like Rad60 SUMO-like
104 SUZ12suppressor60.40012.447DUF2070 (PF09843, IPR019204): Predicted membrane protein (DUF2070)
VEFS-Box (PF09733, IPR019135): VEFS-Box of polycomb protein
105 TAGLNsuppressor110.5828.274Calponin (PF00402, IPR000557): Calponin family repeat
CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
106 TAGLN2interactor230.40368.393Calponin (PF00402, IPR000557): Calponin family repeat
CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
107 TALDO1interactor110.52713.816TAL_FSA (PF00923, IPR001585): Transaldolase/Fructose-6-phosphate aldolase
108 TCTN2interactor40.1679.529DUF1619 (PF07773, IPR011677): Protein of unknown function (DUF1619)
109 TCTN3interactor60.13325.087DUF1619 (PF07773, IPR011677): Protein of unknown function (DUF1619)
110 TERF1interactor140.52611.663TRF (PF08558, IPR013867): Telomere repeat binding factor (TRF)
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
111 TKTprotein found in more fusions330.361141.621Transket_pyr (PF02779, IPR005475, SM00861): Transketolase, pyrimidine binding domain
Transketolase_C (PF02780, IPR005476): Transketolase, C-terminal domain
Transketolase_N (PF00456, IPR005474): Transketolase, thiamine diphosphate binding domain
112 TNPO3interactor31.0000HEAT (PF02985, IPR000357): HEAT repeat
IFRD (PF05004, IPR007701): Interferon-related developmental regulator (IFRD)
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
113 TP53BP1suppressor70.23837.60953-BP1_Tudor (PF09038, IPR015125): Tumour suppressor p53-binding protein-1 Tudor
BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal
DUF4772 (PF15997, IPR031940): Domain of unknown function (DUF4772)
BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain
114 TRAP1oncoprotein130.47415.494HSP90 (PF00183, IPR001404): Hsp90 protein
HATPase_c_3 (PF13589): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
115 TRIM63interactor90.35715.579DUF349 (PF03993, IPR007139): Domain of Unknown Function (DUF349)
KIP1 (PF07765, IPR011684): KIP1-like protein
RED_C (PF07807, IPR012492): RED-like protein C-terminal region
zf-HIT (PF04438, IPR007529): HIT zinc finger
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
YceG_bac (PF14266, IPR025647): Putative component of 'biosynthetic module'
116 UMPSinteractor60.5333.605OMPdecase (PF00215, IPR001754, SM00934): Orotidine 5'-phosphate decarboxylase / HUMPS family
Pribosyltran (PF00156, IPR000836): Phosphoribosyl transferase domain
117 USP15oncoprotein110.44414.990UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
DUSP (PF06337, IPR006615, SM00695): DUSP domain
Ubiquitin_3 (PF14836, IPR028135): Ubiquitin-like domain
118 VCAM1interactor190.53226.485C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
119 VCPKMTinteractor100Methyltransf_16 (PF10294, IPR019410): Lysine methyltransferase
120 VPS18interactor40.50014.614Pep3_Vps18 (PF05131, IPR007810): Pep3/Vps18/deep orange family
Clathrin (PF00637, IPR000547, SM00299): Region in Clathrin and VPS
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
121 XRN1interactor70.52425.698XRN_N (PF03159, IPR004859): XRN 5'-3' exonuclease N-terminus

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