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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)122
The number (and %) of the onco-proteins47 (38.52 %)
The number (and %) of the tumor suppressors14 (11.48 %)
Total number of binary PPIs (saturation %)1752 (23.74 %)
The number (and %) of affected PPIs120 (6.85 %)
The number of possible different fusions32
PPI diameter5
PPI radius3
The average degree of PPI27.787
Assortativity coefficient-0.1201
The network average Clustering coefficient0.525
The number (and %) of a zero Clustering coefficients3 (2.46 %)
The number (and %) of a zero Betweenness Centrality7 (5.74 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: HNRNPA3,MTFR1L All fusions
Proteins found in more fusions EEF1G (see 1 fusions); STAU1 (see 2 fusions); U2AF2 (see 2 fusions); CUL7 (see 2 fusions); CUL1 (see 3 fusions); CUL3 (see 1 fusions); UBE2N (see 1 fusions); PARK2 (see 1 fusions); VHL (see 1 fusions); HNRNPA3/NONO (see 1 fusions); EWSR1 (see 1 fusions); ITPA (see 1 fusions); COPS5 (see 1 fusions); HDAC5 (see 1 fusions); UBC (see 7 fusions); RPA1 (see 1 fusions); RPLP2 (see 1 fusions); SNW1 (see 1 fusions); PTBP1 (see 1 fusions); SREK1 (see 6 fusions); PUF60 (see 1 fusions); SFPQ (see 6 fusions); SRPK2 (see 1 fusions); COPS5/HNRNPH3 (see 3 fusions); HNRNPL (see 3 fusions); HNRNPD (see 1 fusions); MCM2 (see 1 fusions); UBQLN2 (see 3 fusions); DDX17 (see 4 fusions); MATR3 (see 4 fusions); GAPDH (see 5 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 HNRNPA3parental protein1130.2432921.895IATP (PF04568, IPR007648): Mitochondrial ATPase inhibitor, IATP
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
2 MTFR1Lparental protein70.048725.823Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
3 ARHGDIAinteractor110.7331.773Rho_GDI (PF02115, IPR000406): RHO protein GDP dissociation inhibitor
4 ARMC1interactor30.33357.952Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
HMA (PF00403, IPR006121): Heavy-metal-associated domain
5 ARRB1interactor140.6376.369Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain
Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain
6 ATP1B1interactor50.7001.083Na_K-ATPase (PF00287, IPR000402): Sodium / potassium ATPase beta chain
7 ATP5Binteractor230.47424.256AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain
ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain
NACHT (PF05729): NACHT domain
8 BTRConcoprotein170.53315.325WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
F-box-like (PF12937, IPR001810): F-box-like
9 CAND1interactor540.499130.610Adaptin_N (PF01602, IPR002553): Adaptin N terminal region
DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981)
HEAT (PF02985, IPR000357): HEAT repeat
TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20)
RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1
DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385)
MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II
10 CD81interactor210.52120.736Tetraspannin (PF00335, IPR018499): Tetraspanin family
11 CHMP2Ainteractor50.5002.590Snf7 (PF03357, IPR005024): Snf7
12 CLK1interactor61.0000PDGF_N (PF04692, IPR006782): Platelet-derived growth factor, N terminal region
Pkinase (PF00069, IPR000719): Protein kinase domain
13 CNBPoncoprotein80.6071.616zf-CCHC (PF00098, IPR001878): Zinc knuckle
zf-ribbon_3 (PF13248): zinc-ribbon domain
14 COPS5protein found in more fusions480.55464.000JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
15 CRIP1interactor40.8330.250LIM (PF00412, IPR001781, SM00132): LIM domain
16 CRY1interactor180.52214.148DNA_photolyase (PF00875, IPR006050): DNA photolyase
FAD_binding_7 (PF03441, IPR005101): FAD binding domain of DNA photolyase
17 CUL1suppressor540.489148.890Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
18 CUL2suppressor350.66221.448Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
19 CUL3protein found in more fusions600.439330.740Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
20 CUL4Boncoprotein310.69916.487Cullin (PF00888, IPR001373, SM00182): Cullin family
EBP50_C (PF09007, IPR015098): EBP50, C-terminal
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
PG_binding_4 (PF12229, IPR022029): Putative peptidoglycan binding domain
MDFI (PF15316, IPR026134): MyoD family inhibitor
21 CUL5suppressor370.63837.959Cullin (PF00888, IPR001373, SM00182): Cullin family
GlutR_dimer (PF00745, IPR015896): Glutamyl-tRNAGlu reductase, dimerisation domain
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
22 CUL7protein found in more fusions490.404135.913ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10)
Cullin (PF00888, IPR001373, SM00182): Cullin family
DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918)
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7
23 CYB5Binteractor31.0000Cyt-b5 (PF00173, IPR001199, SM01117): Cytochrome b5-like Heme/Steroid binding domain
MIP (PF00230, IPR000425): Major intrinsic protein
24 DCUN1D1interactor290.7718.884Cullin_binding (PF03556, IPR005176): Cullin binding
UBA_4 (PF14555): UBA-like domain
25 DDX17protein found in more fusions500.441149.965CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Ferritin (PF00210, IPR008331): Ferritin-like domain
GRP (PF07172, IPR010800): Glycine rich protein family
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
26 EEDsuppressor370.47050.553WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
27 EEF1Gprotein found in more fusions270.45223.990EF1G (PF00647, IPR001662): Elongation factor 1 gamma, conserved domain
GST_C (PF00043, IPR004046): Glutathione S-transferase, C-terminal domain
GST_N (PF02798, IPR004045): Glutathione S-transferase, N-terminal domain
SAPS (PF04499, IPR007587): SIT4 phosphatase-associated protein
28 EEF2interactor290.55937.611EFG_C (PF00679, IPR000640, SM00838): Elongation factor G C-terminus
EFG_IV (PF03764, IPR005517, SM00889): Elongation factor G, domain IV
GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
EFG_II (PF14492, IPR009022): Elongation Factor G, domain II
29 ESR1suppressor350.43977.022Oest_recep (PF02159, IPR001292): Oestrogen receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal
30 EWSR1oncoprotein450.456108.717RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
Keratin_2_head (PF16208, IPR032444): Keratin type II head
31 FBXW11interactor230.61918.274WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
F-box-like (PF12937, IPR001810): F-box-like
32 FDPSinteractor60.6672.725polyprenyl_synt (PF00348, IPR000092): Polyprenyl synthetase
33 FN1oncoprotein510.381236.389fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain
fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
34 FUSsuppressor560.481284.956Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
Limkain-b1 (PF11608, IPR024582): Limkain b1
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
Keratin_2_head (PF16208, IPR032444): Keratin type II head
35 GAPDHoncoprotein320.45432.299Gp_dh_C (PF02800, IPR020829): Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
Gp_dh_N (PF00044, IPR020828, SM00846): Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
OstA (PF03968, IPR005653): OstA-like protein
36 GCN1interactor150.4386.014Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
HEAT (PF02985, IPR000357): HEAT repeat
CLASP_N (PF12348, IPR024395): CLASP N terminal
MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal
TFCD_C (PF12612, IPR022577): Tubulin folding cofactor D C terminal
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II
37 HAUS2interactor70.333127.187DpnII (PF04556, IPR007637): DpnII restriction endonuclease
HAUS2 (PF15003, IPR028346): HAUS augmin-like complex subunit 2
38 HDAC5protein found in more fusions290.43789.887Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
NOA36 (PF06524, IPR010531): NOA36 protein
Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3
HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
39 HDGFinteractor140.5386.694PWWP (PF00855, IPR000313, SM00293): PWWP domain
40 HNRNPA1interactor860.349869.958RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1
41 HNRNPA1L2interactor120.5769.095RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1
42 HNRNPA2B1oncoprotein650.393314.810RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
43 HNRNPABinteractor490.423185.821CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain
GRP (PF07172, IPR010800): Glycine rich protein family
NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
DUF2462 (PF09495, IPR019034): Protein of unknown function (DUF2462)
44 HNRNPDoncoprotein610.459173.014CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain
NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Keratin_2_head (PF16208, IPR032444): Keratin type II head
45 HNRNPDLinteractor430.574157.440CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
46 HNRNPFinteractor470.50279.492RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Spot_14 (PF07084, IPR009786): Thyroid hormone-inducible hepatic protein Spot 14
zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger
47 HNRNPH1oncoprotein570.494132.909RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger
48 HNRNPH2interactor380.56347.183RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger
49 HNRNPH3protein found in more fusions430.491122.589Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
50 HNRNPKoncoprotein600.406256.472ROKNT (PF08067, IPR012987): ROKNT (NUC014) domain
KH_1 (PF00013, IPR004088, SM00322): KH domain
51 HNRNPLprotein found in more fusions470.53689.089RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Dscam_C (PF12355, IPR021012): Down syndrome cell adhesion molecule C terminal
RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
52 HNRNPUinteractor670.383404.244CDC45 (PF02724, IPR003874): CDC45-like protein
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
SAP (PF02037, IPR003034, SM00513): SAP domain
SPRY (PF00622, IPR003877, SM00449): SPRY domain
AAA_33 (PF13671): AAA domain
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
53 HSD17B10interactor240.47133.980adh_short (PF00106, IPR002198): short chain dehydrogenase
54 HSPA5oncoprotein530.489257.972HSP70 (PF00012, IPR013126): Hsp70 protein
55 HSPA8oncoprotein430.404154.738HSP70 (PF00012, IPR013126): Hsp70 protein
56 ICAM1oncoprotein130.5643.308Adhes-Ig_like (PF09085, IPR015169): Adhesion molecule, immunoglobulin-like
C2-set_2 (PF08205, IPR013162): CD80-like C2-set immunoglobulin domain
ICAM_N (PF03921, IPR013768): Intercellular adhesion molecule (ICAM), N-terminal domain
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
57 IFIT3interactor90.9290.154TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
TPR_10 (PF13374, IPR011990): Tetratricopeptide repeat
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_17 (PF13431): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
58 IGSF8oncoprotein150.6104.984V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
59 IL7Rinteractor150.5525.731fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
60 ITGA4interactor440.420142.682FG-GAP (PF01839, IPR013517): FG-GAP repeat
Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region
Integrin_alpha2 (PF08441, IPR013649): Integrin alpha
61 ITPAprotein found in more fusions41.0000Ham1p_like (PF01725, IPR002637): Ham1 family
62 LIN28Ainteractor30.6670.222CSD (PF00313, IPR002059): 'Cold-shock' DNA-binding domain
zf-CCHC (PF00098, IPR001878): Zinc knuckle
zf-CCHC_6 (PF15288): Zinc knuckle
63 MAGEA12interactor100MAGE (PF01454, IPR002190): MAGE family
MAGE_N (PF12440, IPR021072): Melanoma associated antigen family N terminal
64 MATR3protein found in more fusions420.57749.939DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-U1 (PF06220, IPR013085, SM00451): U1 zinc finger
Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54
zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding
RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
FAM60A (PF15396, IPR026065): Protein Family FAM60A
65 MCM2oncoprotein530.456163.920AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA)
MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
66 MCM5oncoprotein260.52928.949MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
67 MRPS26interactor50.7000.338MRP-S26 (PF14943, IPR026140): Mitochondrial ribosome subunit S26
68 NEDD8interactor350.65124.455ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
69 NONOoncoprotein370.408108.666GvpL_GvpF (PF06386, IPR009430): Gas vesicle synthesis protein GvpL/GvpF
NOPS (PF08075, IPR012975): NOPS (NUC059) domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PAS_7 (PF12860): PAS fold
SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
70 NTRK1oncoprotein620.393351.481I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
71 OBSL1interactor400.48964.058BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain
Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
72 OLFM4suppressor100DUF1373 (PF07117, IPR009803): Protein of unknown function (DUF1373)
FPP (PF05911, IPR008587): Filament-like plant protein, long coiled-coil
OLF (PF02191, IPR003112, SM00284): Olfactomedin-like domain
73 PAN2interactor200.51617.355RNase_T (PF00929, IPR013520): Exonuclease
UCH_1 (PF13423, IPR001394): Ubiquitin carboxyl-terminal hydrolase
WD40_like (PF17005, IPR031544): WD40-like domain
74 PARK2suppressor280.49335.244IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
75 PGK1interactor200.61119.810PGK (PF00162, IPR001576): Phosphoglycerate kinase
76 PHB2interactor170.49317.743DUF2605 (PF10792, IPR019728): Protein of unknown function (DUF2605)
Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family
77 PHF6suppressor90.8061.546zf-HC5HC2H (PF13771): PHD-like zinc-binding domain
YqfQ (PF14181, IPR025571): YqfQ-like protein
78 PRG2interactor100Lectin_C (PF00059, IPR001304, SM00034): Lectin C-type domain
DUF4628 (PF15429, IPR027851): Domain of unknown function (DUF4628)
79 PROSCinteractor60.8670.265Ala_racemase_N (PF01168, IPR001608): Alanine racemase, N-terminal domain
80 PTBP1oncoprotein450.55176.204RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
81 PUF60protein found in more fusions240.63611.824RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Titin_Z (PF09042, IPR015129): Titin Z
TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence
82 RAB10oncoprotein110.4366.411Ras (PF00071, IPR001806, SM00173): Ras family
83 RAB1Aoncoprotein120.45515.631Ras (PF00071, IPR001806, SM00173): Ras family
84 RAB7Asuppressor160.49223.732Ras (PF00071, IPR001806, SM00173): Ras family
85 RAD21oncoprotein200.48921.911Rad21_Rec8 (PF04824, IPR006909): Conserved region of Rad21 / Rec8 like protein
Rad21_Rec8_N (PF04825, IPR006910): N terminus of Rad21 / Rec8 like protein
FAM176 (PF14851): FAM176 family
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
86 RNF2interactor300.36985.590zf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
87 RPA1suppressor420.53089.163Rep-A_N (PF04057, IPR007199): Replication factor-A protein 1, N-terminal domain
Rep_fac-A_C (PF08646, IPR013955): Replication factor-A C terminal domain
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
REPA_OB_2 (PF16900, IPR031657): Replication protein A OB domain
88 RPA2oncoprotein390.517152.436RPA_C (PF08784, IPR014892): Replication protein A C terminal
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
RMI2 (PF16100, IPR032245): RecQ-mediated genome instability protein 2
89 RPA3interactor370.54063.011Rep_fac-A_3 (PF08661, IPR013970): Replication factor A protein 3
90 RPLP2protein found in more fusions260.50328.222Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
91 RPS13interactor270.35084.421Ribosomal_S13_N (PF08069, IPR012606): Ribosomal S13/S15 N-terminal domain
Ribosomal_S15 (PF00312, IPR000589): Ribosomal protein S15
92 RPS28interactor190.53812.146Ribosomal_S28e (PF01200, IPR000289): Ribosomal protein S28e
93 RSU1interactor21.0000LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
94 SCARNA22interactor180.6544.550NA
95 SDF4interactor40.500102.497Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region
EF-hand_1 (PF00036, IPR002048, SM00054): EF hand
EF-hand_5 (PF13202, IPR002048): EF hand
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
96 SF3A2interactor180.6737.029Cytadhesin_P30 (PF07271, IPR009896): Cytadhesin P30/P32
PRP4 (PF08799, IPR014906): pre-mRNA processing factor 4 (PRP4) like
Totivirus_coat (PF05518, IPR008871): Totivirus coat protein
zf-met (PF12874): Zinc-finger of C2H2 type
ARL6IP6 (PF15062, IPR029383): Haemopoietic lineage transmembrane helix
SF3A2 (PF16835, IPR031781): Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11)
97 SFPQoncoprotein420.43288.203GRP (PF07172, IPR010800): Glycine rich protein family
Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein
NOPS (PF08075, IPR012975): NOPS (NUC059) domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
PAT1 (PF09770, IPR019167): Topoisomerase II-associated protein PAT1
CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance
98 SIRT7interactor230.39949.893DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563)
SIR2 (PF02146, IPR003000): Sir2 family
99 SMURF1interactor210.53217.498C2 (PF00168, IPR000008, SM00239): C2 domain
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
100 SNW1protein found in more fusions350.57446.383SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
SIR4_SID (PF16991, IPR031556): Sir4 SID domain
101 SREK1protein found in more fusions150.60413.546Ureide_permease (PF07168, IPR009834): Ureide permease
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
RP-C_C (PF11800, IPR021760): Replication protein C C-terminal region
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915)
BRD4_CDT (PF17105, IPR031354): C-terminal domain of bromodomain protein 4
102 SRPK2oncoprotein190.58216.151DUF1387 (PF07139, IPR009816): Protein of unknown function (DUF1387)
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
Pkinase (PF00069, IPR000719): Protein kinase domain
S-antigen (PF05756, IPR008825): S-antigen protein
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
103 SRRM2interactor320.56045.769cwf21 (PF08312, IPR013170, SM01115): cwf21 domain
DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754)
Pap_E4 (PF02711, IPR003861): E4 protein
RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6
CTD (PF12815, IPR024945, SM01104): Spt5 C-terminal nonapeptide repeat binding Spt4
DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614)
104 STAU1protein found in more fusions360.49663.942dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
Staufen_C (PF16482, IPR032478): Staufen C-terminal domain
105 STK24interactor50.5001.120DUF1241 (PF06840, IPR009652): Protein of unknown function (DUF1241)
Pkinase (PF00069, IPR000719): Protein kinase domain
106 SYNCRIPinteractor560.401213.912RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Limkain-b1 (PF11608, IPR024582): Limkain b1
107 TARDBPinteractor430.55558.516RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
108 TOP1oncoprotein300.51732.847DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764)
Topoisom_I (PF01028, IPR013500): Eukaryotic DNA topoisomerase I, catalytic core
Topoisom_I_N (PF02919, IPR008336): Eukaryotic DNA topoisomerase I, DNA binding fragment
MCM_bind (PF09739, IPR019140): Mini-chromosome maintenance replisome factor
Sox_N (PF12444, IPR022151): Sox developmental protein N terminal
Topo_C_assoc (PF14370, IPR025834): C-terminal topoisomerase domain
DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614)
TonB_N (PF16031): TonB N-terminal region
109 TP63suppressor110.5783.080Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
P53 (PF00870, IPR011615): P53 DNA-binding domain
P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
110 U2AF2protein found in more fusions490.505102.156RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Transformer (PF06495, IPR010519): Fruit fly transformer protein
111 UBCprotein found in more fusions490.452191.549ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
112 UBE2Nprotein found in more fusions70.5330.661UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
113 UBQLN2protein found in more fusions90.8210.367Clathrin-link (PF09268, IPR015348): Clathrin, heavy-chain linker
Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
XPC-binding (PF09280, IPR015360): XPC-binding domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
SUZ (PF12752, IPR024771): SUZ domain
Fur_reg_FbpB (PF13040, IPR025004): Fur-regulated basic protein B
114 UQCRC2oncoprotein90.3896.144Peptidase_M16 (PF00675, IPR011765): Insulinase (Peptidase family M16)
Peptidase_M16_C (PF05193, IPR007863): Peptidase M16 inactive domain
115 USP37interactor100.7222.485UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
UCH_N (PF16674, IPR032069): N-terminal of ubiquitin carboxyl-terminal hydrolase 37
116 VCAM1interactor360.41387.394C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
117 VHLsuppressor240.7834.238Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP)
VHL (PF01847, IPR022772): VHL beta domain
VHL_C (PF17211): VHL box domain
118 WWOXsuppressor160.45812.217adh_short (PF00106, IPR002198): short chain dehydrogenase
WW (PF00397, IPR001202, SM00456): WW domain
119 XPO1interactor270.288724.619CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
120 YWHAEoncoprotein320.39585.38714-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
121 ZBTB1interactor60.4002.352BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
zf-BED (PF02892, IPR003656, SM00614): BED zinc finger
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding
zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies)
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
122 ZFAND6interactor30.6670.105zf-A20 (PF01754, IPR002653, SM00259): A20-like zinc finger
zf-AN1 (PF01428, IPR000058, SM00154): AN1-like Zinc finger

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