1 |
FANCB | parental protein | 9 | 0.778 | 254.000 | DP (PF08781, IPR014889, SM01138): Transcription factor DP |
2 |
PSMB1 | parental protein | 119 | 0.191 | 7360.957 | Proteasome (PF00227, IPR001353): Proteasome subunit |
3 |
ADRM1 | interactor | 40 | 0.908 | 7.869 | Proteasom_Rpn13 (PF04683, IPR006773): Proteasome complex subunit Rpn13 ubiquitin receptor GET2 (PF08690, IPR028143): GET complex subunit GET2 RPN13_C (PF16550, IPR032368): UCH-binding domain |
4 |
AMFR | oncoprotein | 25 | 0.732 | 26.758 | CUE (PF02845, IPR003892, SM00546): CUE domain UbiA (PF01040, IPR000537): UbiA prenyltransferase family zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain |
5 |
AP3M1 | interactor | 7 | 1.000 | 0 | Adap_comp_sub (PF00928, IPR008968): Adaptor complexes medium subunit family Clat_adaptor_s (PF01217, IPR022775): Clathrin adaptor complex small chain |
6 |
ASNA1 | interactor | 8 | 0.929 | 0.218 | ArsA_ATPase (PF02374, IPR025723): Anion-transporting ATPase |
7 |
BAG3 | oncoprotein | 26 | 0.707 | 39.284 | BAG (PF02179, IPR003103, SM00264): BAG domain WW (PF00397, IPR001202, SM00456): WW domain |
8 |
BCL3 | oncoprotein | 1 | 0 | 0 | Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) |
9 |
CASP4 | interactor | 1 | 0 | 0 | CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain Peptidase_C14 (PF00656, IPR011600): Caspase domain |
10 |
CCT5 | interactor | 13 | 0.397 | 26.392 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
11 |
CDKN1B | suppressor | 3 | 0.667 | 0.236 | CDI (PF02234, IPR003175): Cyclin-dependent kinase inhibitor Multi-haem_cyto (PF13447): Seven times multi-haem cytochrome CxxCH |
12 |
CENPS | suppressor | 8 | 1.000 | 0 | CENP-S (PF15630, IPR029003): CENP-S protein COMMD1_N (PF17221): COMMD1 N-terminal domain |
13 |
CFTR | suppressor | 10 | 0.861 | 0.497 | ABC_membrane (PF00664, IPR001140): ABC transporter transmembrane region ABC_tran (PF00005, IPR003439): ABC transporter Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain Rotamase_2 (PF13145, IPR000297): PPIC-type PPIASE domain CFTR_R (PF14396, IPR025837): Cystic fibrosis TM conductance regulator (CFTR), regulator domain |
14 |
CLIC4 | oncoprotein | 8 | 0.821 | 1.840 | GST_C_2 (PF13410): Glutathione S-transferase, C-terminal domain GST_N_3 (PF13417, IPR004045): Glutathione S-transferase, N-terminal domain |
15 |
DCP2 | interactor | 1 | 0 | 0 | DCP2 (PF05026, IPR007722, SM01125): Dcp2, box A domain NUDIX (PF00293, IPR000086): NUDIX domain |
16 |
DDB2 | suppressor | 7 | 0.600 | 4.037 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat |
17 |
DSTYK | interactor | 2 | 1.000 | 0 | APH (PF01636, IPR002575): Phosphotransferase enzyme family Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase |
18 |
EPAS1 | suppressor | 7 | 0.667 | 2.800 | Corona_I (PF03187, IPR004876): Corona nucleocapsid I protein HIF-1a_CTAD (PF08778, IPR014887): HIF-1 alpha C terminal transactivation domain HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold HIF-1 (PF11413, IPR021537): Hypoxia-inducible factor-1 PAS_11 (PF14598): PAS domain |
19 |
EXOSC6 | protein found in more fusions | 7 | 1.000 | 0 | RNase_PH (PF01138, IPR001247): 3' exoribonuclease family, domain 1 |
20 |
FAAP100 | interactor | 8 | 1.000 | 0 | FANCAA (PF15146, IPR029251): Fanconi anemia-associated |
21 |
FAAP20 | interactor | 9 | 0.778 | 233.265 | UBZ_FAAP20 (PF15750, IPR031490): Ubiquitin-binding zinc-finger FANCA_interact (PF15751, IPR031491): FAAP20 FANCA interaction domain |
22 |
FAAP24 | interactor | 8 | 1.000 | 0 | Rad10 (PF03834, IPR004579): Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_2 (PF12826): Helix-hairpin-helix motif |
23 |
FANCA | oncoprotein | 10 | 0.778 | 323.758 | Fanconi_A (PF03511, IPR003516): Fanconi anaemia group A protein Fanconi_A_N (PF15865, IPR031729): Fanconi anaemia group A protein N terminus |
24 |
FANCG | suppressor | 10 | 0.778 | 864.408 | BTAD (PF03704, IPR005158, SM01043): Bacterial transcriptional activator domain Hpt (PF01627, IPR008207, SM00073): Hpt domain TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_14 (PF13428): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat |
25 |
FANCL | protein found in more fusions | 10 | 0.806 | 15.536 | WD-3 (PF09765, IPR019162): WD-repeat region FANCL_C (PF11793, IPR026850): FANCL C-terminal domain |
26 |
FANCM | interactor | 11 | 0.667 | 47.857 | ERCC4 (PF02732, IPR006166, SM00891): ERCC4 domain MRC1 (PF09444, IPR018564): MRC1-like domain ResIII (PF04851, IPR006935): Type III restriction enzyme, res subunit Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain HHH_2 (PF12826): Helix-hairpin-helix motif FANCM-MHF_bd (PF16783, IPR031879): FANCM to MHF binding domain |
27 |
FBXO28 | interactor | 5 | 0.400 | 4.015 | Exonuc_VII_L (PF02601, IPR020579): Exonuclease VII, large subunit F-box (PF00646, IPR001810, SM00256): F-box domain FAM76 (PF16046, IPR032017): FAM76 protein |
28 |
FKBP8 | protein found in more fusions | 33 | 0.881 | 21.272 | FKBP_C (PF00254, IPR001179): FKBP-type peptidyl-prolyl cis-trans isomerase TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat TPR_16 (PF13432): Tetratricopeptide repeat Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat |
29 |
FN1 | oncoprotein | 27 | 0.459 | 89.185 | fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) |
30 |
HAUS2 | interactor | 3 | 0.667 | 1.000 | DpnII (PF04556, IPR007637): DpnII restriction endonuclease HAUS2 (PF15003, IPR028346): HAUS augmin-like complex subunit 2 |
31 |
HECW2 | interactor | 7 | 0.533 | 3.900 | C2 (PF00168, IPR000008, SM00239): C2 domain WW (PF00397, IPR001202, SM00456): WW domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) Cep57_CLD (PF14073, IPR025913): Centrosome localisation domain of Cep57 RFXA_RFXANK_bdg (PF15289, IPR029316): Regulatory factor X-associated C-terminal binding domain HECW_N (PF16562, IPR032348): N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 |
32 |
HNRNPA2B1 | oncoprotein | 18 | 0.510 | 25.529 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
33 |
HSD17B10 | interactor | 6 | 0.800 | 0.411 | adh_short (PF00106, IPR002198): short chain dehydrogenase |
34 |
INSIG2 | interactor | 15 | 0.924 | 0.801 | INSIG (PF07281, IPR025929): Insulin-induced protein (INSIG) |
35 |
IQCB1 | interactor | 17 | 0.757 | 11.425 | DUF1765 (PF08578, IPR013887): Protein of unknown function (DUF1765) IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif HJURP_C (PF12347, IPR022102): Holliday junction regulator protein family C-terminal repeat Condensin2nSMC (PF12422, IPR024741): Condensin II non structural maintenance of chromosomes subunit |
36 |
ITGA4 | interactor | 23 | 0.506 | 47.783 | FG-GAP (PF01839, IPR013517): FG-GAP repeat Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region Integrin_alpha2 (PF08441, IPR013649): Integrin alpha |
37 |
KIFC3 | oncoprotein | 7 | 0.333 | 157.644 | Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein KxDL (PF10241, IPR019371): Uncharacterized conserved protein Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200) HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1 |
38 |
KRT13 | interactor | 2 | 1.000 | 0 | Filament (PF00038, IPR001664): Intermediate filament protein FliD_N (PF02465, IPR003481): Flagellar hook-associated protein 2 N-terminus Keratin_2_head (PF16208, IPR032444): Keratin type II head |
39 |
KRT15 | interactor | 4 | 0.667 | 2.552 | Filament (PF00038, IPR001664): Intermediate filament protein Keratin_2_head (PF16208, IPR032444): Keratin type II head |
40 |
MAPRE3 | interactor | 2 | 1.000 | 0 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain EB1 (PF03271, IPR004953): EB1-like C-terminal motif |
41 |
MCM2 | oncoprotein | 28 | 0.373 | 119.729 | AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA) MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2 MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain |
42 |
MED4 | interactor | 8 | 0.321 | 20.677 | Med4 (PF10018, IPR019258): Vitamin-D-receptor interacting Mediator subunit 4 |
43 |
MID1 | oncoprotein | 16 | 0.857 | 5.625 | Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain SPRY (PF00622, IPR003877, SM00449): SPRY domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING |
44 |
MRPS9 | interactor | 6 | 0.733 | 1.933 | Ribosomal_S9 (PF00380, IPR000754): Ribosomal protein S9/S16 |
45 |
MYC | oncoprotein | 26 | 0.583 | 61.160 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain Myc_N (PF01056, IPR012682): Myc amino-terminal region |
46 |
NOTCH2 | suppressor | 1 | 0 | 0 | Ank (PF00023, IPR002110, SM00248): Ankyrin repeat EGF (PF00008, IPR000742, SM00181): EGF-like domain EGF_alliinase (PF04863, IPR006947): Alliinase EGF-like domain EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain NOD (PF06816, IPR010660): NOTCH protein NODP (PF07684, IPR011656): NOTCH protein Notch (PF00066, IPR000800, SM00004): LNR domain DUF3454 (PF11936, IPR024600): Domain of unknown function (DUF3454) hEGF (PF12661, IPR013032): Human growth factor-like EGF cEGF (PF12662, IPR026823): Complement Clr-like EGF-like Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) |
47 |
PARK2 | suppressor | 47 | 0.660 | 200.818 | IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
48 |
PASK | interactor | 2 | 1.000 | 0 | Pkinase (PF00069, IPR000719): Protein kinase domain PAS_8 (PF13188, IPR000014): PAS domain PAS_9 (PF13426, IPR000014): PAS domain |
49 |
PCK1 | interactor | 16 | 0.767 | 9.314 | PEPCK (PF00821, IPR008209): Phosphoenolpyruvate carboxykinase |
50 |
PEX19 | interactor | 4 | 1.000 | 0 | Pex19 (PF04614, IPR006708): Pex19 protein family Rod-binding (PF10135, IPR019301): Rod binding protein |
51 |
PGK1 | interactor | 9 | 0.694 | 1.988 | PGK (PF00162, IPR001576): Phosphoglycerate kinase |
52 |
PLK1 | suppressor | 16 | 0.825 | 6.376 | Pkinase (PF00069, IPR000719): Protein kinase domain POLO_box (PF00659, IPR000959): POLO box duplicated region |
53 |
POMP | interactor | 24 | 0.763 | 23.941 | UMP1 (PF05348, IPR008012): Proteasome maturation factor UMP1 |
54 |
PPP4R3A | interactor | 6 | 0.333 | 7.983 | Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies) SMK-1 (PF04802, IPR006887): Component of IIS longevity pathway SMK-1 WH1 (PF00568, IPR000697, SM00461): WH1 domain DUF4611 (PF15387, IPR027893): Domain of unknown function (DUF4611) |
55 |
PSEN1 | oncoprotein | 6 | 0.700 | 3.567 | Presenilin (PF01080, IPR001108): Presenilin LRRC37AB_C (PF14914, IPR029423): LRRC37A/B like protein 1 C-terminal domain |
56 |
PSMA1 | interactor | 66 | 0.494 | 406.714 | Proteasome (PF00227, IPR001353): Proteasome subunit Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature |
57 |
PSMA2 | interactor | 64 | 0.550 | 245.855 | Proteasome (PF00227, IPR001353): Proteasome subunit Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature |
58 |
PSMA3 | interactor | 63 | 0.548 | 239.614 | Proteasome (PF00227, IPR001353): Proteasome subunit Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature |
59 |
PSMA4 | interactor | 55 | 0.624 | 121.112 | Proteasome (PF00227, IPR001353): Proteasome subunit U79_P34 (PF03064, IPR004138): HSV U79 / HCMV P34 Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature |
60 |
PSMA5 | oncoprotein | 66 | 0.482 | 838.892 | Proteasome (PF00227, IPR001353): Proteasome subunit Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature |
61 |
PSMA6 | interactor | 64 | 0.527 | 281.710 | Proteasome (PF00227, IPR001353): Proteasome subunit Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature |
62 |
PSMA7 | protein found in more fusions | 62 | 0.574 | 166.793 | Proteasome (PF00227, IPR001353): Proteasome subunit Peptidase_C65 (PF10275, IPR019400): Peptidase C65 Otubain Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature |
63 |
PSMA8 | interactor | 32 | 0.929 | 4.909 | Proteasome (PF00227, IPR001353): Proteasome subunit Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature Myb_DNA-bind_5 (PF13873, IPR028002): Myb/SANT-like DNA-binding domain |
64 |
PSMB10 | interactor | 16 | 0.917 | 0.901 | Proteasome (PF00227, IPR001353): Proteasome subunit Pr_beta_C (PF12465, IPR024689): Proteasome beta subunits C terminal |
65 |
PSMB2 | interactor | 57 | 0.590 | 216.278 | Proteasome (PF00227, IPR001353): Proteasome subunit |
66 |
PSMB3 | protein found in more fusions | 66 | 0.496 | 348.022 | Proteasome (PF00227, IPR001353): Proteasome subunit |
67 |
PSMB4 | interactor | 59 | 0.576 | 182.732 | Integrin_b_cyt (PF08725, IPR014836): Integrin beta cytoplasmic domain Proteasome (PF00227, IPR001353): Proteasome subunit |
68 |
PSMB5 | interactor | 57 | 0.603 | 129.113 | Proteasome (PF00227, IPR001353): Proteasome subunit |
69 |
PSMB6 | interactor | 53 | 0.668 | 77.733 | DUF1502 (PF07397, IPR010871): Repeat of unknown function (DUF1502) Proteasome (PF00227, IPR001353): Proteasome subunit |
70 |
PSMB7 | protein found in more fusions | 53 | 0.689 | 82.718 | Proteasome (PF00227, IPR001353): Proteasome subunit Pr_beta_C (PF12465, IPR024689): Proteasome beta subunits C terminal |
71 |
PSMB8 | interactor | 43 | 0.825 | 32.378 | Proteasome (PF00227, IPR001353): Proteasome subunit |
72 |
PSMB9 | interactor | 43 | 0.825 | 18.698 | Proteasome (PF00227, IPR001353): Proteasome subunit |
73 |
PSMC1 | interactor | 48 | 0.776 | 45.396 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA) DivIC (PF04977, IPR007060): Septum formation initiator DUF815 (PF05673, IPR008533): Protein of unknown function (DUF815) Prot_ATP_ID_OB (PF16450, IPR032501): Proteasomal ATPase OB/ID domain |
74 |
PSMC2 | interactor | 52 | 0.749 | 39.696 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) |
75 |
PSMC3 | interactor | 49 | 0.749 | 98.550 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) DUF3713 (PF12506, IPR022186): Protein of unknown function (DUF3713) JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II |
76 |
PSMC4 | interactor | 47 | 0.791 | 60.443 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) NTPase_1 (PF03266, IPR004948): NTPase CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_16 (PF13191): AAA ATPase domain |
77 |
PSMC5 | protein found in more fusions | 51 | 0.749 | 66.103 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) Laminin_II (PF06009, IPR010307): Laminin Domain II RILP (PF11461, IPR021563): Rab interacting lysosomal protein AAA_16 (PF13191): AAA ATPase domain |
78 |
PSMC6 | interactor | 47 | 0.768 | 77.786 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) AAA_2 (PF07724, IPR013093): AAA domain (Cdc48 subfamily) TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein Prot_ATP_ID_OB (PF16450, IPR032501): Proteasomal ATPase OB/ID domain |
79 |
PSMD1 | interactor | 48 | 0.770 | 63.941 | PA26 (PF04636, IPR006730): PA26 p53-induced protein (sestrin) PC_rep (PF01851, IPR002015): Proteasome/cyclosome repeat HEAT_2 (PF13646): HEAT repeats |
80 |
PSMD11 | interactor | 47 | 0.763 | 49.357 | DUF247 (PF03140, IPR004158): Plant protein of unknown function PCI (PF01399, IPR000717, SM00088): PCI domain AAA_16 (PF13191): AAA ATPase domain TPR_12 (PF13424): Tetratricopeptide repeat |
81 |
PSMD12 | interactor | 46 | 0.840 | 18.121 | Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain PCI (PF01399, IPR000717, SM00088): PCI domain |
82 |
PSMD13 | interactor | 44 | 0.820 | 32.019 | Mitovir_RNA_pol (PF05919, IPR008686): Mitovirus RNA-dependent RNA polymerase PCI (PF01399, IPR000717, SM00088): PCI domain |
83 |
PSMD14 | interactor | 49 | 0.778 | 32.728 | JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function |
84 |
PSMD2 | oncoprotein | 52 | 0.692 | 66.079 | PC_rep (PF01851, IPR002015): Proteasome/cyclosome repeat THAP (PF05485, IPR006612, SM00980): THAP domain HEAT_2 (PF13646): HEAT repeats |
85 |
PSMD3 | interactor | 50 | 0.701 | 77.417 | Rpn3_C (PF08375, IPR013586): Proteasome regulatory subunit C-terminal TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat PCI (PF01399, IPR000717, SM00088): PCI domain Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat TSKS (PF15358, IPR028214): Testis-specific serine kinase substrate |
86 |
PSMD4 | interactor | 43 | 0.872 | 14.308 | UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif VWA_2 (PF13519, IPR002035): von Willebrand factor type A domain |
87 |
PSMD5 | interactor | 39 | 0.887 | 11.514 | Proteasom_PSMB (PF10508, IPR019538): Proteasome non-ATPase 26S subunit |
88 |
PSMD6 | interactor | 47 | 0.782 | 45.953 | RPN7 (PF10602, IPR019585): 26S proteasome subunit RPN7 PCI (PF01399, IPR000717, SM00088): PCI domain |
89 |
PSMD7 | interactor | 46 | 0.799 | 51.485 | JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg (PF13012, IPR024969): Maintenance of mitochondrial structure and function Auts2 (PF15336): Autism susceptibility gene 2 protein Coilin_N (PF15862, IPR031722): Coilin N-terminus |
90 |
PSMD8 | interactor | 42 | 0.908 | 6.954 | CSN8_PSD8_EIF3K (PF10075): CSN8/PSMD8/EIF3K family |
91 |
PSME1 | interactor | 30 | 0.833 | 8.675 | PA28_alpha (PF02251, IPR003185): Proteasome activator pa28 alpha subunit PA28_beta (PF02252, IPR003186): Proteasome activator pa28 beta subunit RNase_H2-Ydr279 (PF09468, IPR019024): Ydr279p protein family (RNase H2 complex component) |
92 |
PSME2 | interactor | 31 | 0.795 | 15.006 | PA28_alpha (PF02251, IPR003185): Proteasome activator pa28 alpha subunit PA28_beta (PF02252, IPR003186): Proteasome activator pa28 beta subunit |
93 |
PSME3 | protein found in more fusions | 32 | 0.710 | 37.497 | PA28_alpha (PF02251, IPR003185): Proteasome activator pa28 alpha subunit PA28_beta (PF02252, IPR003186): Proteasome activator pa28 beta subunit |
94 |
PSME4 | interactor | 18 | 0.876 | 1.894 | Filament (PF00038, IPR001664): Intermediate filament protein HEAT (PF02985, IPR000357): HEAT repeat DUF3437 (PF11919, IPR021843): Domain of unknown function (DUF3437) BLM10_mid (PF16507, IPR032430): Proteasome-substrate-size regulator, mid region |
95 |
PSMG3 | interactor | 12 | 0.909 | 0.446 | PAC3 (PF10178, IPR018788): Proteasome assembly chaperone 3 |
96 |
PYCRL | interactor | 8 | 1.000 | 0 | F420_oxidored (PF03807, IPR028939): NADP oxidoreductase coenzyme F420-dependent zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger P5CR_dimer (PF14748, IPR029036): Pyrroline-5-carboxylate reductase dimerisation |
97 |
RAD23A | oncoprotein | 41 | 0.809 | 74.394 | UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain XPC-binding (PF09280, IPR015360): XPC-binding domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
98 |
RBM8A | interactor | 3 | 1.000 | 0 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
99 |
RIOK3 | interactor | 3 | 1.000 | 0 | RIO1 (PF01163, IPR018934): RIO1 family |
100 |
RPL10A | interactor | 11 | 0.836 | 2.285 | Ribosomal_L1 (PF00687, IPR028364): Ribosomal protein L1p/L10e family |
101 |
RPL24 | interactor | 10 | 0.778 | 7.077 | MAS20 (PF02064, IPR002056): MAS20 protein import receptor Ribosomal_L24e (PF01246, IPR000988): Ribosomal protein L24e |
102 |
RPL5 | suppressor | 14 | 0.615 | 19.274 | Ribosomal_L18_c (PF14204, IPR025607): Ribosomal L18 C-terminal region Ribosomal_L5e (PF17144): Ribosomal large subunit proteins 60S L5, and 50S L18 |
103 |
RPL7A | interactor | 12 | 0.712 | 7.401 | Ribosomal_L7Ae (PF01248, IPR004038): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family |
104 |
RPP30 | interactor | 3 | 0.667 | 0.095 | RNase_P_p30 (PF01876, IPR002738): RNase P subunit p30 |
105 |
RPP38 | interactor | 8 | 1.000 | 0 | Ribosomal_L7Ae (PF01248, IPR004038): Ribosomal protein L7Ae/L30e/S12e/Gadd45 family |
106 |
RPS15A | interactor | 17 | 0.507 | 30.501 | Ribosomal_S8 (PF00410, IPR000630): Ribosomal protein S8 |
107 |
RPS23 | interactor | 8 | 1.000 | 0 | Ribosom_S12_S23 (PF00164, IPR006032): Ribosomal protein S12/S23 |
108 |
SEC13 | interactor | 5 | 0.500 | 1.700 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 (PF16529, IPR032401): WD40 region of Ge1, enhancer of mRNA-decapping protein |
109 |
SERPINB2 | interactor | 1 | 0 | 0 | Serpin (PF00079, IPR023796, SM00093): Serpin (serine protease inhibitor) |
110 |
SERPINE1 | interactor | 3 | 1.000 | 0 | Serpin (PF00079, IPR023796, SM00093): Serpin (serine protease inhibitor) |
111 |
SF3A1 | interactor | 8 | 0.786 | 4.233 | TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit Surp (PF01805, IPR000061, SM00648): Surp module ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family PRP21_like_P (PF12230, IPR022030): Pre-mRNA splicing factor PRP21 like protein |
112 |
SHFM1 | interactor | 33 | 0.754 | 16.109 | CLLAC (PF15675, IPR031379): CLLAC-motif containing domain |
113 |
SLX1B | interactor | 15 | 0.943 | 0.767 | GIY-YIG (PF01541, IPR000305, SM00465): GIY-YIG catalytic domain FANCL_C (PF11793, IPR026850): FANCL C-terminal domain |
114 |
SNX3 | interactor | 4 | 0.667 | 2.000 | PX (PF00787, IPR001683, SM00312): PX domain |
115 |
SRSF2 | oncoprotein | 10 | 0.556 | 6.966 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TP2 (PF01254, IPR000678): Nuclear transition protein 2 Transformer (PF06495, IPR010519): Fruit fly transformer protein Apt1 (PF10351, IPR019443): Golgi-body localisation protein domain DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457) |
116 |
SUGT1 | interactor | 7 | 0.571 | 1.893 | CheC (PF04509, IPR007597): CheC-like family CS (PF04969, IPR007052): CS domain SGS (PF05002, IPR007699): SGS domain TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat TPR_16 (PF13432): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat |
117 |
SYVN1 | protein found in more fusions | 17 | 0.975 | 0.300 | Alpha_GJ (PF03229, IPR004913): Alphavirus glycoprotein J zf-DHHC (PF01529, IPR001594): DHHC palmitoyltransferase zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain |
118 |
THBS3 | oncoprotein | 2 | 0 | 0 | EGF (PF00008, IPR000742, SM00181): EGF-like domain EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain Laminin_G_2 (PF02210, IPR001791): Laminin G domain TSP_3 (PF02412, IPR003367): Thrombospondin type 3 repeat TSP_C (PF05735, IPR008859): Thrombospondin C-terminal region COMP (PF11598, IPR024665): Cartilage oligomeric matrix protein cEGF (PF12662, IPR026823): Complement Clr-like EGF-like EGF_3 (PF12947, IPR024731): EGF domain |
119 |
TRAF1 | oncoprotein | 5 | 0.667 | 1.567 | HypA (PF01155, IPR000688): Hydrogenase/urease nickel incorporation, metallochaperone, hypA SlyX (PF04102, IPR007236): SlyX TRAF_BIRC3_bd (PF16673, IPR032070): TNF receptor-associated factor BIRC3 binding domain |
120 |
TRIM27 | oncoprotein | 10 | 0.417 | 138.264 | IncA (PF04156, IPR007285): IncA protein SPRY (PF00622, IPR003877, SM00449): SPRY domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease |
121 |
UBC | protein found in more fusions | 53 | 0.440 | 754.504 | ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
122 |
UBE2A | interactor | 8 | 0.524 | 8.288 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
123 |
UBE2V1 | interactor | 8 | 0.393 | 9.201 | UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme |
124 |
UBE4B | suppressor | 5 | 0.500 | 2.500 | DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180) NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region Ufd2P_core (PF10408, IPR019474): Ubiquitin elongating factor core U-box (PF04564, IPR003613, SM00504): U-box domain DUF4568 (PF15132, IPR027919): Domain of unknown function (DUF4568) |
125 |
UCHL5 | oncoprotein | 39 | 0.919 | 23.768 | Peptidase_C12 (PF01088, IPR001578): Ubiquitin carboxyl-terminal hydrolase, family 1 |
126 |
UFM1 | interactor | 3 | 0.667 | 1.000 | Ufm1 (PF03671, IPR005375): Ubiquitin fold modifier 1 protein |
127 |
UNK | interactor | 4 | 0.500 | 2.000 | MbeD_MobD (PF04899, IPR006983): MbeD/MobD like NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450) zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) zf-CCCH_2 (PF14608): RNA-binding, Nab2-type zinc finger Torus (PF16131, IPR032297): Torus domain |
128 |
VCAM1 | interactor | 23 | 0.522 | 57.621 | C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain |
129 |
VHL | suppressor | 16 | 0.438 | 28.410 | Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP) VHL (PF01847, IPR022772): VHL beta domain VHL_C (PF17211): VHL box domain |