1 |
ERCC1 | parental protein | 30 | 0.101 | 1067.442 | Rad10 (PF03834, IPR004579): Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 (PF14520): Helix-hairpin-helix domain |
2 |
CTPS2 | parental protein | 28 | 0.111 | 1136.185 | CTP_synth_N (PF06418, IPR017456): CTP synthase N-terminus GATase (PF00117, IPR017926): Glutamine amidotransferase class-I |
3 |
ACAT1 | interactor | 4 | 0.333 | 33.877 | Thiolase_C (PF02803, IPR020617): Thiolase, C-terminal domain Thiolase_N (PF00108, IPR020616): Thiolase, N-terminal domain |
4 |
APP | protein found in more fusions | 9 | 0.071 | 232.939 | APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP) BUD22 (PF09073, IPR015158): BUD22 IncA (PF04156, IPR007285): IncA protein Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein |
5 |
C15orf40 | interactor | 2 | 0 | 36.506 | DUF167 (PF02594, IPR003746, SM01152): Uncharacterised ACR, YggU family COG1872 |
6 |
CDC5L | interactor | 8 | 0.333 | 94.314 | OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain |
7 |
COL9A1 | interactor | 1 | 0 | 0 | Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies) DUF826 (PF05696, IPR008544): Protein of unknown function (DUF826) Laminin_G_2 (PF02210, IPR001791): Laminin G domain |
8 |
CTBP2 | protein found in more fusions | 3 | 0 | 7.782 | 2-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain |
9 |
DHPS | protein found in more fusions | 4 | 1.000 | 0 | DS (PF01916, IPR002773): Deoxyhypusine synthase |
10 |
EHD1 | interactor | 8 | 0.667 | 11.438 | Gp-FAR-1 (PF05823, IPR008632): Nematode fatty acid retinoid binding protein (Gp-FAR-1) Gtr1_RagA (PF04670, IPR006762): Gtr1/RagA G protein conserved region Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand EHD_N (PF16880, IPR031692): N-terminal EH-domain containing protein |
11 |
EHD4 | interactor | 7 | 0.524 | 34.099 | GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand EHD_N (PF16880, IPR031692): N-terminal EH-domain containing protein |
12 |
ENPP6 | interactor | 1 | 0 | 0 | Phosphodiest (PF01663, IPR002591): Type I phosphodiesterase / nucleotide pyrophosphatase |
13 |
ERCC4 | oncoprotein | 13 | 0.308 | 188.317 | ERCC4 (PF02732, IPR006166, SM00891): ERCC4 domain LUC7 (PF03194, IPR004882): LUC7 N_terminus T2SSM_b (PF10741, IPR007690): Type II secretion system (T2SS), protein M subtype b HHH_5 (PF14520): Helix-hairpin-helix domain |
14 |
FANCG | suppressor | 5 | 0.333 | 35.516 | BTAD (PF03704, IPR005158, SM01043): Bacterial transcriptional activator domain Hpt (PF01627, IPR008207, SM00073): Hpt domain TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_14 (PF13428): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat |
15 |
FGFR1 | oncoprotein | 2 | 0 | 0 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain ig (PF00047, IPR013151, SM00409): Immunoglobulin domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase |
16 |
GTF2H1 | oncoprotein | 5 | 0.700 | 5.297 | BSD (PF03909, IPR005607, SM00751): BSD domain PH_TFIIH (PF08567, IPR013876): TFIIH p62 subunit, N-terminal domain |
17 |
GTF2I | interactor | 8 | 0.464 | 41.851 | GTF2I (PF02946, IPR004212): GTF2I-like repeat |
18 |
HSF1 | protein found in more fusions | 8 | 0.429 | 86.515 | DUF247 (PF03140, IPR004158): Plant protein of unknown function Vert_HS_TF (PF06546, IPR010542): Vertebrate heat shock transcription factor HSF_DNA-bind (PF00447, IPR000232, SM00415): HSF-type DNA-binding |
19 |
KTN1 | oncoprotein | 4 | 1.000 | 0 | ETRAMP (PF09716, IPR006389): Malarial early transcribed membrane protein (ETRAMP) Fez1 (PF06818): Fez1 Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family Fzo_mitofusin (PF04799, IPR006884): fzo-like conserved region HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper IncA (PF04156, IPR007285): IncA protein OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) PTPS (PF01242, IPR007115): 6-pyruvoyl tetrahydropterin synthase Spectrin (PF00435, IPR002017): Spectrin repeat TBPIP (PF07106, IPR010776): Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1 TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407) Fimbrial_PilY2 (PF14481, IPR029497): Type 4 fimbrial biogenesis protein PilY2 Muted (PF14942, IPR017243): Organelle biogenesis, Muted-like protein BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2 |
20 |
LRSAM1 | interactor | 7 | 0.533 | 50.207 | Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif) SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif) LRR_8 (PF13855, IPR001611): Leucine rich repeat zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
21 |
MAGIX | interactor | 1 | 0 | 0 | PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) |
22 |
METTL1 | interactor | 5 | 0.600 | 45.550 | Methyltransf_4 (PF02390, IPR003358): Putative methyltransferase |
23 |
MKRN3 | oncoprotein | 3 | 0 | 40.510 | zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) MKRN1_C (PF15815, IPR031644): E3 ubiquitin-protein ligase makorin-1, C-terminal Torus (PF16131, IPR032297): Torus domain zf-3CxxC_2 (PF17180): Zinc-binding domain |
24 |
MSH2 | suppressor | 7 | 0.533 | 17.996 | MutS_I (PF01624, IPR007695): MutS domain I MutS_II (PF05188, IPR007860): MutS domain II MutS_V (PF00488, IPR000432, SM00534): MutS domain V MutS_III (PF05192, IPR007696, SM00533): MutS domain III AAA_27 (PF13514): AAA domain |
25 |
MTMR2 | interactor | 6 | 0.800 | 1.867 | GRAM (PF02893, IPR004182, SM00568): GRAM domain Myotub-related (PF06602, IPR010569): Myotubularin-like phosphatase domain 3-PAP (PF12578, IPR022587): Myotubularin-associated protein NYD-SP28_assoc (PF14775, IPR029440): Sperm tail C-terminal domain |
26 |
MUS81 | suppressor | 5 | 0.600 | 3.377 | ERCC4 (PF02732, IPR006166, SM00891): ERCC4 domain MutL (PF13941, IPR006230): MutL protein HHH_8 (PF14716, IPR010996): Helix-hairpin-helix domain |
27 |
NASP | interactor | 2 | 1.000 | 0 | Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1 DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913) SlyX (PF04102, IPR007236): SlyX TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat TraV (PF09676, IPR014118): Type IV conjugative transfer system lipoprotein (TraV) SHNi-TPR (PF10516, IPR019544): SHNi-TPR XhlA (PF10779, IPR019715): Haemolysin XhlA TPR_8 (PF13181, IPR019734): Tetratricopeptide repeat CCSAP (PF15748, IPR029774): Centriole, cilia and spindle-associated MAP17 (PF15807, IPR031627): Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 |
28 |
NTRK1 | oncoprotein | 17 | 0.208 | 505.967 | I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain |
29 |
NUCB1 | interactor | 6 | 0.600 | 10.277 | DUF1104 (PF06518, IPR009488): Protein of unknown function (DUF1104) Spc24 (PF08286, IPR013252): Spc24 subunit of Ndc80 DUF2967 (PF11179, IPR021349): Protein of unknown function (DUF2967) DUF3552 (PF12072, IPR022711): Domain of unknown function (DUF3552) EF-hand_7 (PF13499, IPR011992): EF-hand domain pair |
30 |
OTUD5 | interactor | 1 | 0 | 0 | OTU (PF02338, IPR003323): OTU-like cysteine protease Peptidase_C65 (PF10275, IPR019400): Peptidase C65 Otubain |
31 |
PLIN3 | interactor | 7 | 0.533 | 41.615 | Perilipin (PF03036, IPR004279): Perilipin family |
32 |
POLR2A | protein found in more fusions | 10 | 0.361 | 104.416 | RNA_pol_Rpb1_1 (PF04997, IPR007080): RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 (PF00623, IPR000722): RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 (PF04983, IPR007066): RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 (PF05000, IPR007083): RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_5 (PF04998, IPR007081): RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_R (PF05001, IPR000684): RNA polymerase Rpb1 C-terminal repeat |
33 |
PRKDC | protein found in more fusions | 10 | 0.361 | 68.706 | FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain NUC194 (PF08163, IPR012582): NUC194 domain PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase |
34 |
RNF2 | interactor | 8 | 0.190 | 68.377 | zf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like |
35 |
RPL23A | interactor | 4 | 0.667 | 5.450 | Ribosomal_L23 (PF00276, IPR013025): Ribosomal protein L23 Ribosomal_L23eN (PF03939, IPR005633): Ribosomal protein L23, N-terminal domain |
36 |
RPL37A | interactor | 3 | 0.333 | 12.133 | Ribosomal_L37ae (PF01780, IPR002674): Ribosomal L37ae protein family |
37 |
SLAMF1 | interactor | 2 | 0 | 0 | ig (PF00047, IPR013151, SM00409): Immunoglobulin domain SLAM (PF06214, IPR010407): Signaling lymphocytic activation molecule (SLAM) protein |
38 |
SLX1A | interactor | 4 | 0.833 | 0.400 | GIY-YIG (PF01541, IPR000305, SM00465): GIY-YIG catalytic domain FANCL_C (PF11793, IPR026850): FANCL C-terminal domain |
39 |
SLX1B | interactor | 5 | 0.800 | 1.067 | GIY-YIG (PF01541, IPR000305, SM00465): GIY-YIG catalytic domain FANCL_C (PF11793, IPR026850): FANCL C-terminal domain |
40 |
SLX4 | suppressor | 10 | 0.378 | 57.151 | BTB (PF00651, IPR013069, SM00225): BTB/POZ domain Slx4 (PF09494, IPR018574): Slx4 endonuclease zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger) |
41 |
SLX4IP | interactor | 4 | 1.000 | 0 | UPF0492 (PF15744, IPR031479): Uncharacterized protein family UPF0492 |
42 |
SNX3 | interactor | 1 | 0 | 0 | PX (PF00787, IPR001683, SM00312): PX domain |
43 |
SPG21 | interactor | 1 | 0 | 0 | Abhydrolase_1 (PF00561, IPR000073): alpha/beta hydrolase fold |
44 |
TAF10 | interactor | 6 | 0.733 | 3.644 | TFIID_30kDa (PF03540, IPR003923): Transcription initiation factor TFIID 23-30kDa subunit |
45 |
TAF12 | interactor | 5 | 0.600 | 17.895 | TFIID_20kDa (PF03847, IPR003228): Transcription initiation factor TFIID subunit A |
46 |
TAF6 | interactor | 7 | 0.476 | 56.048 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal TAF6_C (PF07571, IPR011442): TAF6 C-terminal HEAT repeat domain Spo0A_C (PF08769, IPR014879): Sporulation initiation factor Spo0A C terminal TAF (PF02969, IPR004823, SM00803): TATA box binding protein associated factor (TAF) |
47 |
TAF7 | interactor | 4 | 1.000 | 0 | DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) ELM2 (PF01448, IPR000949): ELM2 domain TAFII55_N (PF04658, IPR006751): TAFII55 protein conserved region XhlA (PF10779, IPR019715): Haemolysin XhlA Noelin-1 (PF12308, IPR022082): Neurogenesis glycoprotein |
48 |
TBP | interactor | 8 | 0.524 | 86.881 | TBP (PF00352, IPR000814): Transcription factor TFIID (or TATA-binding protein, TBP) EPL1 (PF10513, IPR019542): Enhancer of polycomb-like Med3 (PF11593, IPR020998): Mediator complex subunit 3 fungal |
49 |
TOPBP1 | protein found in more fusions | 4 | 0.667 | 1.000 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain PTCB-BRCT (PF12738, IPR001357): twin BRCT domain RTT107_BRCT_5 (PF16770, IPR001357): Regulator of Ty1 transposition protein 107 BRCT domain |
50 |
TRMT2B | interactor | 1 | 0 | 0 | tRNA_U5-meth_tr (PF05958, IPR010280): tRNA (Uracil-5-)-methyltransferase |
51 |
TWF2 | interactor | 3 | 0.333 | 31.845 | Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein |
52 |
UBL7 | oncoprotein | 2 | 1.000 | 0 | UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family |
53 |
UHRF1 | interactor | 6 | 0.300 | 55.639 | PHD (PF00628, IPR019787, SM00249): PHD-finger SAD_SRA (PF02182, IPR003105, SM00466): SAD/SRA domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family TTD (PF12148, IPR021991): Tandem tudor domain within UHRF1 zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) zf-RING_10 (PF16685, IPR032043): zinc RING finger of MSL2 |
54 |
USHBP1 | interactor | 4 | 0.667 | 0.667 | DASH_Dam1 (PF08653, IPR013962): DASH complex subunit Dam1 HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper SlyX (PF04102, IPR007236): SlyX MCC-bdg_PDZ (PF10506, IPR019536): PDZ domain of MCC-2 bdg protein for Usher syndrome YlqD (PF11068, IPR021297): YlqD protein DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404) CAGE1 (PF15066, IPR029381): Cancer-associated gene protein 1 family TEX13 (PF15186, IPR028193): Testis-expressed sequence 13 protein family |
55 |
USP45 | interactor | 3 | 1.000 | 0 | HNH (PF01844, IPR002711): HNH endonuclease UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein LELP1 (PF15042, IPR026076): Late cornified envelope-like proline-rich protein 1 |
56 |
VPS37B | interactor | 3 | 0 | 23.858 | Mod_r (PF07200, IPR009851): Modifier of rudimentary (Mod(r)) protein |
57 |
WARS | interactor | 9 | 0.361 | 65.594 | tRNA-synt_1b (PF00579, IPR002305): tRNA synthetases class I (W and Y) WHEP-TRS (PF00458, IPR000738, SM00991): WHEP-TRS domain |
58 |
XPA | oncoprotein | 7 | 0.429 | 49.960 | XPA_C (PF05181, IPR022656): XPA protein C-terminus XPA_N (PF01286, IPR022652): XPA protein N-terminal MscS_TM (PF12794, IPR025692): Mechanosensitive ion channel inner membrane domain 1 zinc_ribbon_2 (PF13240, IPR026870): zinc-ribbon domain |
59 |
XPO1 | interactor | 11 | 0.127 | 295.825 | CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain Xpo1 (PF08389, IPR013598): Exportin 1-like protein Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region |