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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)296
The number (and %) of the onco-proteins50 (16.89 %)
The number (and %) of the tumor suppressors19 (6.42 %)
Total number of binary PPIs (saturation %)756 (1.73 %)
The number (and %) of affected PPIs295 (39.02 %)
The number of possible different fusions27
PPI diameter4
PPI radius3
The average degree of PPI4.736
Assortativity coefficient-0.4493
The network average Clustering coefficient0.470
The number (and %) of a zero Clustering coefficients97 (32.77 %)
The number (and %) of a zero Betweenness Centrality158 (53.38 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: HECW2,EPHA5 All fusions
Proteins found in more fusions TUBG1 (see 1 fusions); TRIM25 (see 2 fusions); PRMT5 (see 2 fusions); HMG20A (see 2 fusions); L3MBTL3 (see 1 fusions); GSK3B (see 1 fusions); NCOA5 (see 1 fusions); CSNK2A1/ELAVL1 (see 1 fusions); PSMB3 (see 1 fusions); CENPF (see 1 fusions); PAK4 (see 1 fusions); EEF1D (see 7 fusions); STAT3 (see 2 fusions); EIF2AK2 (see 1 fusions); PSMB7 (see 2 fusions); KMT2A (see 16 fusions); KAT8 (see 1 fusions); PSMA7 (see 2 fusions); USP10 (see 1 fusions); CSNK2A1 (see 1 fusions); HECW1 (see 1 fusions); RING1 (see 1 fusions); NEDD4 (see 1 fusions); TP53 (see 3 fusions); CTNNBL1 (see 1 fusions); SNW1 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 HECW2parental protein2910.00981905.904C2 (PF00168, IPR000008, SM00239): C2 domain
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
Cep57_CLD (PF14073, IPR025913): Centrosome localisation domain of Cep57
RFXA_RFXANK_bdg (PF15289, IPR029316): Regulatory factor X-associated C-terminal binding domain
HECW_N (PF16562, IPR032348): N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2
2 EPHA5parental protein4046.312fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Ephrin_rec_like (PF07699, IPR011641): Putative ephrin-receptor like
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
Ephrin_lbd (PF01404, IPR001090, SM00615): Ephrin receptor ligand binding domain
EphA2_TM (PF14575, IPR027936): Ephrin type-A receptor 2 transmembrane domain
3 ABOoncoprotein100Glyco_transf_6 (PF03414, IPR005076): Glycosyltransferase family 6
4 ACSL4interactor40.8330.286AMP-binding (PF00501, IPR000873): AMP-binding enzyme
AMP-binding_C (PF13193, IPR025110): AMP-binding enzyme C-terminal domain
5 ACTL6Ainteractor90.36121.400Actin (PF00022, IPR004000, SM00268): Actin
6 ACTR5interactor30.6670.667Actin (PF00022, IPR004000, SM00268): Actin
DUF1542 (PF07564, IPR011439): Domain of Unknown Function (DUF1542)
UPF0449 (PF15136, IPR028227): Uncharacterised protein family UPF0449
7 AFF4oncoprotein31.0000AF-4 (PF05110, IPR007797): AF-4 proto-oncoprotein
8 AHCYinteractor40.6670.827AdoHcyase (PF05221, IPR000043, SM00996): S-adenosyl-L-homocysteine hydrolase
AdoHcyase_NAD (PF00670, IPR015878, SM00997): S-adenosyl-L-homocysteine hydrolase, NAD binding domain
9 ALDOCinteractor30.6671.000Glycolytic (PF00274, IPR000741): Fructose-bisphosphate aldolase class-I
10 ALKBH5interactor31.0000Selenoprotein_S (PF06936, IPR009703): Selenoprotein S (SelS)
ApoO (PF09769, IPR019166): Apolipoprotein O
2OG-FeII_Oxy_2 (PF13532, IPR027450): 2OG-Fe(II) oxygenase superfamily
11 AMOTL1interactor2039.240NPV_P10 (PF05531, IPR008702): Nucleopolyhedrovirus P10 protein
Presenilin (PF01080, IPR001108): Presenilin
Angiomotin_C (PF12240, IPR024646): Angiomotin C terminal
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
CCDC-167 (PF15188, IPR028194): Coiled-coil domain-containing protein 167
APC_N_CC (PF16689, IPR032038): Coiled-coil N-terminus of APC, dimerisation domain
12 ANAPC1suppressor90.8612.200PC_rep (PF01851, IPR002015): Proteasome/cyclosome repeat
ANAPC1 (PF12859, IPR024990): Anaphase-promoting complex subunit 1
13 ANAPC4interactor100.8066.000ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
ANAPC4 (PF12896, IPR024790): Anaphase-promoting complex, cyclosome, subunit 4
14 ANAPC5interactor90.8891.600TPR_4 (PF07721, IPR011717): Tetratricopeptide repeat
ANAPC5 (PF12862, IPR026000): Anaphase-promoting complex subunit 5
TPR_6 (PF13174, IPR019734): Tetratricopeptide repeat
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_16 (PF13432): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
15 ANGEL2interactor21.0000Exo_endo_phos (PF03372, IPR005135): Endonuclease/Exonuclease/phosphatase family
16 ANKRD65interactor100Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_3 (PF13606, IPR002110): Ankyrin repeat
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
17 ANXA1suppressor31.0000Annexin (PF00191, IPR018502, SM00335): Annexin
18 APRTinteractor100Pribosyltran (PF00156, IPR000836): Phosphoribosyl transferase domain
19 ARF4interactor30.6671.352Arf (PF00025, IPR006689, SM00177): ADP-ribosylation factor family
20 ARRDC1interactor2039.240Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain
Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain
21 ASCC3interactor100DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
PhoH (PF02562, IPR003714): PhoH-like protein
Sec63 (PF02889, IPR004179, SM00973): Sec63 Brl domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
22 ASTE1interactor100XPG_N (PF00752, IPR006085, SM00485): XPG N-terminal domain
XPG_I_2 (PF12813): XPG domain containing
23 ASXL2interactor21.0000DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180)
K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
HARE-HTH (PF05066, IPR007759): HB1, ASXL, restriction endonuclease HTH domain
ASXH (PF13919, IPR028020): Asx homology domain
PHD_3 (PF13922, IPR026905): PHD domain of transcriptional enhancer, Asx
DUF4551 (PF15087, IPR027878): Protein of unknown function (DUF4551)
24 AVL9interactor100Avl9 (PF09794, IPR018307): Transport protein Avl9
Condensin2nSMC (PF12422, IPR024741): Condensin II non structural maintenance of chromosomes subunit
25 BAIAP2interactor70.33355.573IMD (PF08397, IPR013606): IRSp53/MIM homology domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
26 BAIAP2L1interactor30.6670.667IMD (PF08397, IPR013606): IRSp53/MIM homology domain
MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
SH3_9 (PF14604, IPR001452): Variant SH3 domain
27 C11orf84interactor100FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
28 C17orf53interactor100DUF4539 (PF15072, IPR028045): Domain of unknown function (DUF4539)
29 CABIN1interactor100FAT (PF02259, IPR003151): FAT domain
MEF2_binding (PF09047, IPR015134): MEF2 binding
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
TPR_8 (PF13181, IPR019734): Tetratricopeptide repeat
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_17 (PF13431): Tetratricopeptide repeat
30 CACTINinteractor100TT_ORF2 (PF02957, IPR004118): TT viral ORF2
CactinC_cactus (PF09732, IPR019134, SM01050): Cactus-binding C-terminus of cactin protein
Cactin_mid (PF10312, IPR018816): Conserved mid region of cactin
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
DUF2992 (PF11208, IPR016787): Protein of unknown function (DUF2992)
31 CALM3interactor21.0000EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
32 CALML3interactor21.0000EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
33 CAPZBinteractor30.6670.667Cytochrom_B562 (PF07361, IPR009155): Cytochrome b562
F_actin_cap_B (PF01115, IPR001698): F-actin capping protein, beta subunit
34 CARD14interactor100APG6 (PF04111, IPR007243): Autophagy protein Apg6
CARD (PF00619, IPR001315, SM00114): Caspase recruitment domain
ZapB (PF06005, IPR009252): Cell division protein ZapB
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
TSC22 (PF01166, IPR000580): TSC-22/dip/bun family
Guanylate_kin (PF00625, IPR008145, SM00072): Guanylate kinase
Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase
DUF4472 (PF14739, IPR029329): Domain of unknown function (DUF4472)
PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
35 CBX3interactor70.5336.506Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
DTHCT (PF08070, IPR012542): DTHCT (NUC029) region
Chromo_shadow (PF01393, IPR008251, SM00300): Chromo shadow domain
36 CBX4oncoprotein80.6194.567Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region
CBX7_C (PF17218): CBX family C-terminal motif
37 CCNA1interactor41.0000Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain
Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
Cyclin_N2 (PF16500, IPR032447): N-terminal region of cyclin_N
38 CCNKinteractor31.0000Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain
Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
DUF1387 (PF07139, IPR009816): Protein of unknown function (DUF1387)
39 CDC16interactor81.0000Dynein_light (PF01221, IPR001372): Dynein light chain type 1
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_17 (PF13431): Tetratricopeptide repeat
TPR_16 (PF13432): Tetratricopeptide repeat
SRP_TPR_like (PF17004, IPR031545): Putative TPR-like repeat
40 CDC20oncoprotein140.50032.388WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
41 CDC23interactor150.44048.122ANAPC8 (PF04049, IPR007192): Anaphase promoting complex subunit 8 / Cdc23
DUF772 (PF05598, IPR008490): Transposase domain (DUF772)
Menin (PF05053, IPR007747): Menin
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
TPR_6 (PF13174, IPR019734): Tetratricopeptide repeat
TPR_7 (PF13176, IPR019734): Tetratricopeptide repeat
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_14 (PF13428): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
42 CDC27oncoprotein100.8612.200TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_12 (PF13424): Tetratricopeptide repeat
43 CDT1oncoprotein70.7143.888CDT1 (PF08839, IPR014939, SM01075): DNA replication factor CDT1 like
CDT1_C (PF16679, IPR032054): DNA replication factor Cdt1 C-terminal domain
44 CDYLinteractor21.0000Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain
ECH_1 (PF00378, IPR001753): Enoyl-CoA hydratase/isomerase
ECH_2 (PF16113, IPR032259): Enoyl-CoA hydratase/isomerase
45 CENPFoncoprotein200APG6 (PF04111, IPR007243): Autophagy protein Apg6
ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
Bap31 (PF05529, IPR008417): B-cell receptor-associated protein 31-like
bZIP_1 (PF00170, IPR004827): bZIP transcription factor
DivIC (PF04977, IPR007060): Septum formation initiator
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
ZapB (PF06005, IPR009252): Cell division protein ZapB
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
Fez1 (PF06818): Fez1
Filament (PF00038, IPR001664): Intermediate filament protein
HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
HrpB7 (PF09486, IPR013392): Bacterial type III secretion protein (HrpB7)
IncA (PF04156, IPR007285): IncA protein
Propep_M14 (PF02244, IPR003146): Carboxypeptidase activation peptide
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
Usp (PF00582, IPR006016): Universal stress protein family
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
CENP-F_N (PF10481, IPR018463): Cenp-F N-terminal domain
CENP-F_C_Rb_bdg (PF10490, IPR018302): Rb-binding domain of kinetochore protein Cenp-F/LEK1
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
DUF4140 (PF13600, IPR025554): N-terminal domain of unknown function (DUF4140)
DUF4239 (PF14023, IPR025333): Protein of unknown function (DUF4239)
TolA_bind_tri (PF16331, IPR032519): TolA binding protein trimerisation
GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor
46 CEP55interactor50.8330.286DUF342 (PF03961, IPR005646): Protein of unknown function (DUF342)
ZapB (PF06005, IPR009252): Cell division protein ZapB
EABR (PF12180, IPR022008): TSG101 and ALIX binding domain of CEP55
zf-C2H2_3 (PF13878, IPR028005): zinc-finger of acetyl-transferase ESCO
Cep57_CLD_2 (PF14197, IPR025925): Centrosome localisation domain of PPC89
CC2-LZ (PF16516, IPR032419): Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator
BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2
47 CFL1interactor40.5003.000Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein
48 CHAMP1interactor21.0000Hormone_3 (PF00159, IPR001955): Pancreatic hormone peptide
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain
49 CHEK1suppressor40.8330.400Pkinase (PF00069, IPR000719): Protein kinase domain
50 CHTOPinteractor50.6002.783API5 (PF05918, IPR008383): Apoptosis inhibitory protein 5 (API5)
Lamprin (PF06403, IPR009437): Lamprin
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
51 CITinteractor21.0000ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
CNH (PF00780, IPR001180, SM00036): CNH domain
Dec-1 (PF04624, IPR006718): Dec-1 repeat
DivIC (PF04977, IPR007060): Septum formation initiator
DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948)
Fez1 (PF06818): Fez1
PH (PF00169, IPR001849, SM00233): PH domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
SlyX (PF04102, IPR007236): SlyX
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
DUF2570 (PF10828, IPR022538): Protein of unknown function (DUF2570)
KfrA_N (PF11740, IPR021104): Plasmid replication region DNA-binding N-term
Alanine_zipper (PF11839, IPR021793): Alanine-zipper, major outer membrane lipoprotein
Noelin-1 (PF12308, IPR022082): Neurogenesis glycoprotein
TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
52 CKMT1Binteractor21.0000ATP-gua_Ptrans (PF00217, IPR022414): ATP:guanido phosphotransferase, C-terminal catalytic domain
ATP-gua_PtransN (PF02807, IPR022413): ATP:guanido phosphotransferase, N-terminal domain
53 CNOT10interactor100DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948)
POX (PF07526, IPR006563, SM00574): Associated with HOX
Secretin_N_2 (PF07655, IPR011514): Secretin N-terminal domain
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
TPR_14 (PF13428): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
SRP_TPR_like (PF17004, IPR031545): Putative TPR-like repeat
54 CPSF2interactor50.5003.732RMMBL (PF07521, IPR011108): Zn-dependent metallo-hydrolase RNA specificity domain
Beta-Casp (PF10996, IPR022712, SM01027): Beta-Casp domain
CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal
Lactamase_B_6 (PF16661, IPR001279): Metallo-beta-lactamase superfamily domain
55 CRTC2oncoprotein21.0000TORC_N (PF12884, IPR024783): Transducer of regulated CREB activity, N terminus
TORC_M (PF12885, IPR024784): Transducer of regulated CREB activity middle domain
TORC_C (PF12886, IPR024785): Transducer of regulated CREB activity, C terminus
56 CSNK2A1oncoprotein210.205139.734Pkinase (PF00069, IPR000719): Protein kinase domain
57 CSTF3interactor30.6670.500NRDE-2 (PF08424, IPR013633): NRDE-2, necessary for RNA interference
Suf (PF05843, IPR008847): Suppressor of forked protein (Suf)
TPR_6 (PF13174, IPR019734): Tetratricopeptide repeat
TPR_14 (PF13428): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
58 CTNNBL1protein found in more fusions70.4676.833Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
DASH_Dad4 (PF08650, IPR013959): DASH complex subunit Dad4
CTNNBL (PF08216, IPR013180, SM01156): Catenin-beta-like, Arm-motif containing nuclear
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
59 CTR9interactor80.250120.336DUF702 (PF05142, IPR007818): Domain of unknown function (DUF702)
Pap_E4 (PF02711, IPR003861): E4 protein
SPT16 (PF08644, IPR013953): FACT complex subunit (SPT16/CDC68)
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
DUF2175 (PF09943, IPR018686): Uncharacterized protein conserved in archaea (DUF2175)
TPR_6 (PF13174, IPR019734): Tetratricopeptide repeat
TPR_8 (PF13181, IPR019734): Tetratricopeptide repeat
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_14 (PF13428): Tetratricopeptide repeat
TPR_16 (PF13432): Tetratricopeptide repeat
TPR_19 (PF14559): Tetratricopeptide repeat
60 CYCSinteractor21.0000Cytochrom_C (PF00034, IPR003088): Cytochrome c
61 CYFIP1interactor21.0000DUF1394 (PF07159, IPR009828): Protein of unknown function (DUF1394)
FragX_IP (PF05994, IPR008081): Cytoplasmic Fragile-X interacting family
62 DCUN1D5interactor100Cullin_binding (PF03556, IPR005176): Cullin binding
63 DDTinteractor100MIF (PF01187, IPR001398): Macrophage migration inhibitory factor (MIF)
64 DDX24interactor70.33312.667DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain
Sec62 (PF03839, IPR004728): Translocation protein Sec62
Tti2 (PF10521, IPR018870): Tti2 family
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
65 DHRS7Binteractor100adh_short (PF00106, IPR002198): short chain dehydrogenase
66 DHX36interactor21.0000DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold
HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2)
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
67 DIDO1suppressor100PHD (PF00628, IPR019787, SM00249): PHD-finger
SlyX (PF04102, IPR007236): SlyX
SPOC (PF07744, IPR012921): SPOC domain
TFIIS_M (PF07500, IPR003618): Transcription factor S-II (TFIIS), central domain
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
68 DMAP1interactor80.39314.500DMAP1 (PF05499, IPR008468): DNA methyltransferase 1-associated protein 1 (DMAP1)
SANT_DAMP1_like (PF16282, IPR032563): SANT/Myb-like domain of DAMP1
69 DNAJA2interactor50.7003.352DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
70 DNAJC8interactor30.6670.667DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
SHR3_chaperone (PF08229, IPR013248, SM00786): ER membrane protein SH3
DUF4192 (PF13830, IPR025447): Domain of unknown function (DUF4192)
71 DRG1interactor30.6670.667MMR_HSR1 (PF01926, IPR006073): 50S ribosome-binding GTPase
TGS (PF02824, IPR004095): TGS domain
MMR_HSR1_Xtn (PF16897, IPR031662): C-terminal region of MMR_HSR1 domain
72 DUS3Linteractor21.0000Dus (PF01207, IPR001269): Dihydrouridine synthase (Dus)
zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
73 DYSFinteractor100C2 (PF00168, IPR000008, SM00239): C2 domain
FerA (PF08165, IPR012560): FerA (NUC095) domain
FerB (PF08150, IPR012561): FerB (NUC096) domain
FerI (PF08151, IPR012968): FerI (NUC094) domain
Pex24p (PF06398, IPR010482): Integral peroxisomal membrane peroxin
Ferlin_C (PF16165, IPR032362): Ferlin C-terminus
74 ECM1oncoprotein21.0000ECM1 (PF05782, IPR008605): Extracellular matrix protein 1 (ECM1)
75 EEF1Dprotein found in more fusions60.6002.636EF1_GNE (PF00736, IPR014038, SM00888): EF-1 guanine nucleotide exchange domain
EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region
76 EFNB2interactor5084.489Ephrin (PF00812, IPR001799): Ephrin
TMEM132D_C (PF15706, IPR031436): Mature oligodendrocyte transmembrane protein, TMEM132D, C-term
77 EGFLAMinteractor100EGF (PF00008, IPR000742, SM00181): EGF-like domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Laminin_G_1 (PF00054, IPR001791): Laminin G domain
Laminin_G_2 (PF02210, IPR001791): Laminin G domain
78 EIF2AK2oncoprotein50.66792.409dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
Pkinase (PF00069, IPR000719): Protein kinase domain
79 EIF3Hinteractor50.6003.500Androgen_recep (PF02166, IPR001103): Androgen receptor
JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
NHS (PF15273, IPR024845): NHS-like
80 EIF3Ioncoprotein50.6003.333ISN1 (PF06437, IPR009453): IMP-specific 5'-nucleotidase
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
Ge1_WD40 (PF16529, IPR032401): WD40 region of Ge1, enhancer of mRNA-decapping protein
81 EIF3Jinteractor40.8330.500eIF3_subunit (PF08597, IPR013906): Translation initiation factor eIF3 subunit
82 ELAVL1oncoprotein450.0851046.735RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
83 EMG1interactor100EMG1 (PF03587, IPR005304): EMG1/NEP1 methyltransferase
84 ENAHoncoprotein50.7002.556MAP7 (PF05672, IPR008604): MAP7 (E-MAP-115) family
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
VASP_tetra (PF08776, IPR014885): VASP tetramerisation domain
WH1 (PF00568, IPR000697, SM00461): WH1 domain
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
85 EP400oncoprotein50.8001.067FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide
DDHD (PF02862, IPR004177, SM01127): DDHD domain
GN3L_Grn1 (PF08701, IPR014813): GNL3L/Grn1 putative GTPase
HSA (PF07529, IPR014012, SM00573): HSA
Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
EPL1 (PF10513, IPR019542): Enhancer of polycomb-like
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
DUF3304 (PF11745, IPR021733): Protein of unknown function (DUF3304)
DUF3381 (PF11861, IPR024576): Domain of unknown function (DUF3381)
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
DUF3484 (PF11983, IPR021873): Membrane-attachment and polymerisation-promoting switch
DUF3573 (PF12097, IPR021956): Protein of unknown function (DUF3573)
Myb_DNA-bind_4 (PF13837): Myb/SANT-like DNA-binding domain
EP400_N (PF15790, IPR031575): E1A-binding protein p400, N-terminal
86 ERCC6oncoprotein21.0000Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
Spt5-NGN (PF03439, IPR005100): Early transcription elongation factor of RNA pol II, NGN section
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
87 ERV3-1interactor100TLV_coat (PF00429, IPR018154): ENV polyprotein (coat polyprotein)
88 ESCO1interactor100TMPIT (PF07851, IPR012926): TMPIT-like protein
zf-C2H2_3 (PF13878, IPR028005): zinc-finger of acetyl-transferase ESCO
Acetyltransf_13 (PF13880, IPR028009): ESCO1/2 acetyl-transferase
GOLD_2 (PF13897, IPR009038): Golgi-dynamics membrane-trafficking
89 ETF1interactor21.0000eRF1_1 (PF03463, IPR005140): eRF1 domain 1
eRF1_2 (PF03464, IPR005141): eRF1 domain 2
eRF1_3 (PF03465, IPR005142): eRF1 domain 3
90 EXOSC7interactor21.0000RNase_PH (PF01138, IPR001247): 3' exoribonuclease family, domain 1
RNase_PH_C (PF03725, IPR015847): 3' exoribonuclease family, domain 2
91 FAM120Ainteractor40.333168.937TPR_15 (PF13429): Tetratricopeptide repeat
92 FAM120Binteractor100LRRCT (PF01463, IPR000483, SM00082): Leucine rich repeat C-terminal domain
XPG_I_2 (PF12813): XPG domain containing
DUF4540 (PF15073, IPR027867): Domain of unknown function (DUF4540)
93 FAM133Binteractor100BRF1 (PF07741, IPR011665): Brf1-like TBP-binding domain
DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755)
TSGP1 (PF07771, IPR011694): Tick salivary peptide group 1
NuDC (PF16273, IPR032572): Nuclear distribution C domain
94 FAM189A2interactor30.66739.240CD20 (PF04103, IPR007237): CD20-like family
95 FAM189Binteractor40.333612.830CD20 (PF04103, IPR007237): CD20-like family
TMEM252 (PF15664, IPR031363): Transmembrane protein 252 family
96 FAM60Ainteractor31.0000FAM60A (PF15396, IPR026065): Protein Family FAM60A
97 FBXL15interactor30.33340.240LRV (PF01816, IPR004830): Leucine rich repeat variant
F-box (PF00646, IPR001810, SM00256): F-box domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
98 FOXK2interactor60.33310.545FHA (PF00498, IPR000253, SM00240): FHA domain
Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
99 FRG1interactor100DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754)
FRG1 (PF06229, IPR010414): FRG1-like domain
DUF2235 (PF09994, IPR018712): Uncharacterized alpha/beta hydrolase domain (DUF2235)
100 FZR1suppressor120.56122.240WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
101 GATAD1interactor100GATA (PF00320, IPR000679, SM00401): GATA zinc finger
102 GGCTinteractor100GGACT (PF06094, IPR009288): Gamma-glutamyl cyclotransferase, AIG2-like
AIG2_2 (PF13772): AIG2-like family
103 GIPC1interactor21.0000PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
104 GLCCI1interactor100Herpes_LMP2 (PF07415, IPR010881): Gammaherpesvirus latent membrane protein (LMP2) protein
Pap_E4 (PF02711, IPR003861): E4 protein
DUF2076 (PF09849, IPR018648): Uncharacterized protein conserved in bacteria (DUF2076)
FAM117 (PF15388, IPR026642): Protein Family FAM117
105 GMPPAinteractor200Hexapep (PF00132, IPR001451): Bacterial transferase hexapeptide (six repeats)
NTP_transferase (PF00483, IPR005835): Nucleotidyl transferase
106 GPALPP1interactor100TFIIE-A_C (PF11521, IPR021600): C-terminal general transcription factor TFIIE alpha
DUF3752 (PF12572, IPR022226): Protein of unknown function (DUF3752)
107 GRB10oncoprotein40.50043.173BPS (PF08947, IPR015042): BPS (Between PH and SH2)
PH (PF00169, IPR001849, SM00233): PH domain
RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain
SH2 (PF00017, IPR000980, SM00252): SH2 domain
Argos (PF11581, IPR021633): Antagonist of EGFR signalling, Argos
108 GRNoncoprotein100Granulin (PF00396, IPR000118, SM00277): Granulin
Lustrin_cystein (PF14625, IPR028150): Lustrin, cysteine-rich repeated domain
109 GSK3Bsuppressor80.33315.038Pkinase (PF00069, IPR000719): Protein kinase domain
110 GTF2F2interactor21.0000TFIIF_beta (PF02270, IPR003196): Transcription initiation factor IIF, beta subunit
111 HACD3interactor100PTPLA (PF04387, IPR007482): Protein tyrosine phosphatase-like protein, PTPLA
112 HECW1protein found in more fusions70.3336.519C2 (PF00168, IPR000008, SM00239): C2 domain
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
Keratin_B2_2 (PF13885, IPR002494): Keratin, high sulfur B2 protein
HECW_N (PF16562, IPR032348): N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2
113 HMG20Aprotein found in more fusions60.5005.334DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764)
DUF812 (PF05667, IPR008530): Protein of unknown function (DUF812)
MlaC (PF05494, IPR008869): MlaC protein
HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
114 HSD17B12interactor31.0000adh_short (PF00106, IPR002198): short chain dehydrogenase
115 HSD17B4interactor100adh_short (PF00106, IPR002198): short chain dehydrogenase
MaoC_dehydratas (PF01575, IPR002539): MaoC like domain
SCP2 (PF02036, IPR003033): SCP-2 sterol transfer family
MaoC_dehydrat_N (PF13452): N-terminal half of MaoC dehydratase
116 HSPH1oncoprotein30.6671.000HSP70 (PF00012, IPR013126): Hsp70 protein
SICA_alpha (PF12887, IPR024290): SICA extracellular alpha domain
117 HUS1oncoprotein100Hus1 (PF04005, IPR007150): Hus1-like protein
118 INCENPinteractor100ATP-synt_E (PF05680, IPR008386): ATP synthase E chain
Ctr (PF04145, IPR007274): Ctr copper transporter family
DUF572 (PF04502, IPR007590): Family of unknown function (DUF572)
DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913)
INCENP_ARK-bind (PF03941, IPR005635): Inner centromere protein, ARK binding region
INCENP_N (PF12178, IPR022006): Chromosome passenger complex (CPC) protein INCENP N terminal
DUF3807 (PF12720, IPR024526): Protein of unknown function (DUF3807)
PRKCSH-like (PF12999, IPR028146): Glucosidase II beta subunit-like
119 INTS4interactor100Adaptin_N (PF01602, IPR002553): Adaptin N terminal region
HEAT (PF02985, IPR000357): HEAT repeat
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
120 KAT2Ainteractor110.28935.235Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family
PCAF_N (PF06466, IPR009464): PCAF (P300/CBP-associated factor) N-terminal domain
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
NICE-1 (PF15845, IPR031698): Cysteine-rich C-terminal 1 family
121 KAT8protein found in more fusions51.0000MOZ_SAS (PF01853, IPR002717): MOZ/SAS family
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
Tudor-knot (PF11717, IPR025995): RNA binding activity-knot of a chromodomain
122 KCTD6interactor31.0000BTB_2 (PF02214, IPR003131): BTB/POZ domain
123 KDM4Dinteractor31.0000JmjC (PF02373, IPR003347, SM00558): JmjC domain, hydroxylase
JmjN (PF02375, IPR003349, SM00545): jmjN domain
124 KIAA0586interactor100TALPID3 (PF15324, IPR029246): Hedgehog signalling target
125 KINinteractor100KOW (PF00467, IPR005824, SM00739): KOW motif
SecM (PF06558, IPR009502): Secretion monitor precursor protein (SecM)
Kin17_mid (PF10357, IPR019447): Domain of Kin17 curved DNA-binding protein
zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies)
126 KMT2Aoncoprotein100.47215.153AT_hook (PF02178, IPR017956, SM00384): AT hook motif
DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
FYRC (PF05965, IPR003889, SM00542): F/Y rich C-terminus
FYRN (PF05964, IPR003888, SM00541): F/Y-rich N-terminus
Peptidase_S49_N (PF08496, IPR013703): Peptidase family S49 N-terminal
PHD (PF00628, IPR019787, SM00249): PHD-finger
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
SET (PF00856, IPR001214, SM00317): SET domain
zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
zf-HC5HC2H (PF13771): PHD-like zinc-binding domain
DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834)
127 KPNA1interactor70.33314.550Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
IBB (PF01749, IPR002652): Importin beta binding domain
Arm_3 (PF16186, IPR032413): Atypical Arm repeat
128 L3MBTL3protein found in more fusions40.6671.000CDC45 (PF02724, IPR003874): CDC45-like protein
DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510)
Glyco_hydro_2_N (PF02837, IPR006104): Glycosyl hydrolases family 2, sugar binding domain
MBT (PF02820, IPR004092, SM00561): mbt repeat
SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
zf-C2HC (PF01530, IPR002515, SM00343): Zinc finger, C2HC type
Calci_bind_CcbP (PF11535, IPR020994): Calcium binding
Apelin (PF15360, IPR026155): APJ endogenous ligand
129 LACRTinteractor100NA
130 LAMB1interactor21.0000Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus
CorA (PF01544, IPR002523): CorA-like Mg2+ transporter protein
DUF812 (PF05667, IPR008530): Protein of unknown function (DUF812)
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
YscO (PF07321, IPR009929): Type III secretion protein YscO
Laminin_EGF (PF00053, IPR002049, SM00180): Laminin EGF domain
Laminin_N (PF00055, IPR008211, SM00136): Laminin N-terminal (Domain VI)
Alanine_zipper (PF11839, IPR021793): Alanine-zipper, major outer membrane lipoprotein
Ntox1 (PF15500, IPR029137): Putative RNase-like toxin, toxin_1
131 LAMC1interactor50.5004.601BRE1 (PF08647, IPR013956): BRE1 E3 ubiquitin ligase
Laminin_B (PF00052, IPR000034): Laminin B (Domain IV)
Laminin_I (PF06008, IPR009254): Laminin Domain I
LPP (PF04728, IPR006817): Lipoprotein leucine-zipper
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
LOH1CR12 (PF10158, IPR018780): Tumour suppressor protein
Laminin_EGF (PF00053, IPR002049, SM00180): Laminin EGF domain
Laminin_N (PF00055, IPR008211, SM00136): Laminin N-terminal (Domain VI)
Alanine_zipper (PF11839, IPR021793): Alanine-zipper, major outer membrane lipoprotein
Metal_resist (PF13801, IPR025961): Heavy-metal resistance
CCDC-167 (PF15188, IPR028194): Coiled-coil domain-containing protein 167
132 LARP4Binteractor21.0000La (PF05383, IPR006630, SM00715): La domain
133 LDLRAD4interactor30.33340.240Ldl_recept_a (PF00057, IPR002172, SM00192): Low-density lipoprotein receptor domain class A
DUF2615 (PF11027, IPR020309): Protein of unknown function (DUF2615)
134 LGALS7suppressor21.0000Gal-bind_lectin (PF00337, IPR001079, SM00908): Galactoside-binding lectin
135 LMNB1interactor40.5002.667Filament (PF00038, IPR001664): Intermediate filament protein
LTD (PF00932, IPR001322): Lamin Tail Domain
136 LOC390760interactor100NA
137 LSM14Ainteractor41.0000API5 (PF05918, IPR008383): Apoptosis inhibitory protein 5 (API5)
FDF (PF09532, IPR019050, SM01199): FDF domain
GRP (PF07172, IPR010800): Glycine rich protein family
LSM14 (PF12701, IPR025609): Scd6-like Sm domain
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
138 LSM14Binteractor100FDF (PF09532, IPR019050, SM01199): FDF domain
LSM14 (PF12701, IPR025609): Scd6-like Sm domain
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
139 LYNX1interactor100Toxin_1 (PF00087, IPR003571): Snake toxin
UPAR_LY6 (PF00021, IPR001526): u-PAR/Ly-6 domain
140 MACF1oncoprotein100ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
CTV_P33 (PF07184, IPR010803): Citrus tristeza virus P33 protein
DnaI_N (PF07319, IPR009928): Primosomal protein DnaI N-terminus
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
DUF19 (PF01579, IPR002542): Domain of unknown function (DUF19)
FliJ (PF02050, IPR012823): Flagellar FliJ protein
GAS2 (PF02187, IPR003108, SM00243): Growth-Arrest-Specific Protein 2 Domain
Laminin_II (PF06009, IPR010307): Laminin Domain II
Peptidase_S49 (PF01343, IPR002142): Peptidase family S49
Prefoldin_2 (PF01920, IPR002777): Prefoldin subunit
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
Spectrin (PF00435, IPR002017): Spectrin repeat
SYF2 (PF08231, IPR013260): SYF2 splicing factor
KxDL (PF10241, IPR019371): Uncharacterized conserved protein
Plectin (PF00681, IPR001101, SM00250): Plectin repeat
Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like
DUF3813 (PF12758, IPR024217): Protein of unknown function (DUF3813)
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
TEX12 (PF15219, IPR029193): Testis-expressed 12
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
141 MAP1Sinteractor21.0000Lactamase_B_6 (PF16661, IPR001279): Metallo-beta-lactamase superfamily domain
142 MAP2oncoprotein3039.240MAP2_projctn (PF08377, IPR013588): MAP2/Tau projection domain
Tubulin-binding (PF00418, IPR001084): Tau and MAP protein, tubulin-binding repeat
RII_binding_1 (PF10522, IPR018459): RII binding domain
CCSAP (PF15748, IPR029774): Centriole, cilia and spindle-associated
143 MAP7D1interactor100BRF1 (PF07741, IPR011665): Brf1-like TBP-binding domain
Exonuc_VII_L (PF02601, IPR020579): Exonuclease VII, large subunit
MAP7 (PF05672, IPR008604): MAP7 (E-MAP-115) family
NAM-associated (PF14303, IPR029466): No apical meristem-associated C-terminal domain
SOBP (PF15279, IPR026092): Sine oculis-binding protein
DUF4887 (PF16228, IPR032615): Domain of unknown function (DUF4887)
144 MARK1interactor21.0000KA1 (PF02149, IPR001772): Kinase associated domain 1
Pkinase (PF00069, IPR000719): Protein kinase domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
145 MAZinteractor21.0000zf-BED (PF02892, IPR003656, SM00614): BED zinc finger
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
DUF2057 (PF09829, IPR018635): Uncharacterized protein conserved in bacteria (DUF2057)
zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding
DUF3597 (PF12200, IPR022016): Domain of unknown function (DUF3597)
DUF3682 (PF12446, IPR022152): Protein of unknown function (DUF3682)
zf-met (PF12874): Zinc-finger of C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
146 MBIPinteractor60.5005.311DUF1192 (PF06698, IPR009579): Protein of unknown function (DUF1192)
147 MECP2interactor31.0000K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
MBD (PF01429, IPR001739, SM00391): Methyl-CpG binding domain
SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region
IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal
148 MED12oncoprotein40.8330.667Med12 (PF09497, IPR019035): Transcription mediator complex subunit Med12
Peptidase_S15 (PF02129, IPR000383): X-Pro dipeptidyl-peptidase (S15 family)
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
Med19 (PF10278, IPR019403): Mediator of RNA pol II transcription subunit 19
DUF2877 (PF11392, IPR021530): Protein of unknown function (DUF2877)
Med12-PQL (PF12144, IPR021989): Eukaryotic Mediator 12 catenin-binding domain
Med12-LCEWAV (PF12145, IPR021990): Eukaryotic Mediator 12 subunit domain
CYSTM (PF12734, IPR028144): Cysteine-rich TM module stress tolerance
149 MED14interactor31.0000Med14 (PF08638, IPR013947): Mediator complex subunit MED14
150 MED16interactor60.400167.451WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Med16 (PF11635, IPR021665): Mediator complex subunit 16
151 MEIOBinteractor100Pox_H7 (PF04787, IPR006872): Late protein H7
Spt4 (PF06093, IPR022800): Spt4/RpoE2 zinc finger
DZR (PF12773, IPR025874): Double zinc ribbon
REPA_OB_2 (PF16900, IPR031657): Replication protein A OB domain
152 METAP1interactor21.0000Peptidase_M24 (PF00557, IPR001714): Metallopeptidase family M24
zf-C6H2 (PF15801, IPR031615): zf-MYND-like zinc finger, mRNA-binding
153 MICALL1interactor40.5002.667CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
LIM (PF00412, IPR001781, SM00132): LIM domain
DUF3585 (PF12130, IPR022735): Protein of unknown function (DUF3585)
FAM70 (PF14967, IPR028014): FAM70 protein
154 MIOSinteractor21.0000zinc_ribbon_16 (PF17034, IPR031488): Zinc-ribbon like family
155 MOB1Asuppressor100Mob1_phocein (PF03637, IPR005301): Mob1/phocein family
156 MORC2interactor100Prefoldin_2 (PF01920, IPR002777): Prefoldin subunit
zf-CW (PF07496, IPR011124): CW-type Zinc Finger
EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region
Alanine_zipper (PF11839, IPR021793): Alanine-zipper, major outer membrane lipoprotein
HATPase_c_3 (PF13589): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
Snapin_Pallidin (PF14712, IPR028119): Snapin/Pallidin
157 MORC4interactor2083.755zf-CW (PF07496, IPR011124): CW-type Zinc Finger
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
HATPase_c_3 (PF13589): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
158 MOSoncoprotein100Pkinase (PF00069, IPR000719): Protein kinase domain
159 MPGinteractor100Pur_DNA_glyco (PF02245, IPR003180): Methylpurine-DNA glycosylase (MPG)
160 MRM3interactor21.0000SpoU_methylase (PF00588, IPR001537): SpoU rRNA Methylase family
SpoU_sub_bind (PF08032, IPR013123, SM00967): RNA 2'-O ribose methyltransferase substrate binding
161 MRPS9interactor50.4005.167Ribosomal_S9 (PF00380, IPR000754): Ribosomal protein S9/S16
162 MTHFD1Linteractor100FTHFS (PF01268, IPR000559): Formate--tetrahydrofolate ligase
THF_DHG_CYH (PF00763, IPR020630): Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain
THF_DHG_CYH_C (PF02882, IPR020631): Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain
163 NAIPinteractor100BIR (PF00653, IPR001370, SM00238): Inhibitor of Apoptosis domain
NACHT (PF05729): NACHT domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
Fer4_9 (PF13187, IPR017896): 4Fe-4S dicluster domain
164 NCKAP5interactor100bZIP_1 (PF00170, IPR004827): bZIP transcription factor
SurA_N_2 (PF13623): SurA N-terminal domain
NCKAP5 (PF15246, IPR032769): Nck-associated protein 5, Peripheral clock protein
DUF4789 (PF16033, IPR031993): Domain of unknown function (DUF4789)
165 NCOA5suppressor200Macoilin (PF09726, IPR019130): Transmembrane protein
166 NEDD4suppressor200.012491.527Rota_NS26 (PF01525, IPR002512): Rotavirus NS26
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
167 NELFAinteractor21.0000CathepsinC_exc (PF08773, IPR014882): Cathepsin C exclusion domain
DUF4106 (PF13388, IPR025179): Protein of unknown function (DUF4106)
168 NFX1interactor21.0000R3H (PF01424, IPR001374, SM00393): R3H domain
XPG_I (PF00867, IPR006086, SM00484): XPG I-region
zf-NF-X1 (PF01422, IPR000967, SM00438): NF-X1 type zinc finger
169 NOSIPinteractor30.6671.100Rtf2 (PF04641, IPR027799): Rtf2 RING-finger
U-box (PF04564, IPR003613, SM00504): U-box domain
zf-NOSIP (PF15906, IPR031790): Zinc-finger of nitric oxide synthase-interacting protein
170 NPLOC4interactor30.6670.949NPL4 (PF05021, IPR007717): NPL4 family
zf-NPL4 (PF05020, IPR007716): NPL4 family, putative zinc binding region
UN_NPL4 (PF11543, IPR024682): Nuclear pore localisation protein NPL4
171 NSMCE4Ainteractor21.0000Nse4_C (PF08743, IPR014854): Nse4 C-terminal
Nse4-Nse3_bdg (PF15412, IPR029225): Binding domain of Nse4/EID3 to Nse3-MAGE
172 NTHL1interactor21.0000HhH-GPD (PF00730, IPR003265): HhH-GPD superfamily base excision DNA repair protein
173 NTPCRinteractor100NTPase_1 (PF03266, IPR004948): NTPase
174 NUDCD1interactor100CS (PF04969, IPR007052): CS domain
175 NUDT16L1interactor21.0000HEAT_PBS (PF03130, IPR004155, SM00567): PBS lyase HEAT-like repeat
176 OSBPL8interactor100CDC45 (PF02724, IPR003874): CDC45-like protein
DUF1980 (PF09323, IPR015402): Domain of unknown function (DUF1980)
Oxysterol_BP (PF01237, IPR000648): Oxysterol-binding protein
PH (PF00169, IPR001849, SM00233): PH domain
177 PAFAH1B2oncoprotein2083.755Lipase_GDSL_2 (PF13472, IPR013830): GDSL-like Lipase/Acylhydrolase family
178 PAK4protein found in more fusions40.6670.500PBD (PF00786, IPR000095, SM00285): P21-Rho-binding domain
Pkinase (PF00069, IPR000719): Protein kinase domain
179 PBRM1suppressor30.6671.000BAH (PF01426, IPR001025, SM00439): BAH domain
BRF1 (PF07741, IPR011665): Brf1-like TBP-binding domain
CHDNT (PF08073, IPR012958): CHDNT (NUC034) domain
Sporozoite_P67 (PF05642, IPR008845): Sporozoite P67 surface antigen
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
DUF3504 (PF12012, IPR021893): Domain of unknown function (DUF3504)
180 PCinteractor100Biotin_carb_C (PF02785, IPR005482, SM00878): Biotin carboxylase C-terminal domain
Biotin_lipoyl (PF00364, IPR000089): Biotin-requiring enzyme
Biotin_carb_N (PF00289, IPR005481): Biotin carboxylase, N-terminal domain
CPSase_L_D2 (PF02786, IPR005479): Carbamoyl-phosphate synthase L chain, ATP binding domain
HMGL-like (PF00682, IPR000891): HMGL-like
PYC_OADA (PF02436, IPR003379): Conserved carboxylase domain
181 PEX11Binteractor200PEX11 (PF05648, IPR008733): Peroxisomal biogenesis factor 11 (PEX11)
182 PHC2interactor80.47610.000SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
zf-CGNR (PF11706, IPR021005): CGNR zinc finger
DUF4692 (PF15763, IPR031517): Domain of unknown function (DUF4692)
PHC2_SAM_assoc (PF16616): Unstructured region on Polyhomeotic-like protein 1 and 2
183 PHF3interactor100Mem_trans (PF03547, IPR004776): Membrane transport protein
PHD (PF00628, IPR019787, SM00249): PHD-finger
SPOC (PF07744, IPR012921): SPOC domain
TFIIS_M (PF07500, IPR003618): Transcription factor S-II (TFIIS), central domain
zf-HC5HC2H (PF13771): PHD-like zinc-binding domain
DUF4724 (PF15852, IPR031711): Domain of unknown function (DUF4724)
PNISR (PF15996, IPR031937): Arginine/serine-rich protein PNISR
184 PHF6suppressor100zf-HC5HC2H (PF13771): PHD-like zinc-binding domain
YqfQ (PF14181, IPR025571): YqfQ-like protein
185 PIP5K1Aoncoprotein21.0000PIP5K (PF01504, IPR002498): Phosphatidylinositol-4-phosphate 5-Kinase
186 PKN2interactor60.40053.462C2 (PF00168, IPR000008, SM00239): C2 domain
HR1 (PF02185, IPR011072, SM00742): Hr1 repeat
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
SKA2 (PF16740, IPR026762): Spindle and kinetochore-associated protein 2
187 PKN3interactor30.333152.720HR1 (PF02185, IPR011072, SM00742): Hr1 repeat
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding
188 PNPinteractor31.0000PNP_UDP_1 (PF01048, IPR000845): Phosphorylase superfamily
189 POLR2Binteractor60.26760.499RNA_pol_Rpb2_1 (PF04563, IPR007644): RNA polymerase beta subunit
RNA_pol_Rpb2_3 (PF04565, IPR007645): RNA polymerase Rpb2, domain 3
RNA_pol_Rpb2_4 (PF04566, IPR007646): RNA polymerase Rpb2, domain 4
RNA_pol_Rpb2_5 (PF04567, IPR007647): RNA polymerase Rpb2, domain 5
RNA_pol_Rpb2_6 (PF00562, IPR007120): RNA polymerase Rpb2, domain 6
RNA_pol_Rpb2_7 (PF04560, IPR007641): RNA polymerase Rpb2, domain 7
190 POLRMTinteractor21.0000DUF615 (PF04751, IPR006839): Protein of unknown function (DUF615)
PSD2 (PF07624, IPR011478): Protein of unknown function (DUF1585)
RNA_pol (PF00940, IPR002092): DNA-dependent RNA polymerase
PPR_3 (PF13812, IPR002885): Pentatricopeptide repeat domain
RPOL_N (PF14700, IPR029262): DNA-directed RNA polymerase N-terminal
191 POP1interactor40.6670.667POP1 (PF06978, IPR009723): Ribonucleases P/MRP protein subunit POP1
POPLD (PF08170, IPR012590): POPLD (NUC188) domain
192 PPIBinteractor30.6671.000Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
193 PRDX2interactor21.0000AhpC-TSA (PF00578, IPR000866): AhpC/TSA family
1-cysPrx_C (PF10417, IPR019479): C-terminal domain of 1-Cys peroxiredoxin
194 PRKG1interactor100Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
Med4 (PF10018, IPR019258): Vitamin-D-receptor interacting Mediator subunit 4
cNMP_binding (PF00027, IPR000595, SM00100): Cyclic nucleotide-binding domain
195 PRMT5protein found in more fusions50.5002.067PRMT5 (PF05185, IPR025799): PRMT5 arginine-N-methyltransferase
196 PSMA7protein found in more fusions60.7003.000Proteasome (PF00227, IPR001353): Proteasome subunit
Peptidase_C65 (PF10275, IPR019400): Peptidase C65 Otubain
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
197 PSMB1interactor60.5336.000Proteasome (PF00227, IPR001353): Proteasome subunit
198 PSMB3protein found in more fusions70.5335.900Proteasome (PF00227, IPR001353): Proteasome subunit
199 PSMB7protein found in more fusions51.0000Proteasome (PF00227, IPR001353): Proteasome subunit
Pr_beta_C (PF12465, IPR024689): Proteasome beta subunits C terminal
200 PWP2interactor40.8330.500Utp12 (PF04003, IPR007148): Dip2/Utp12 Family
Utp13 (PF08625, IPR013934): Utp13 specific WD40 associated domain
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
201 PXDNinteractor100An_peroxidase (PF03098, IPR002007): Animal haem peroxidase
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
LRRCT (PF01463, IPR000483, SM00082): Leucine rich repeat C-terminal domain
VWC (PF00093, IPR001007, SM00214): von Willebrand factor type C domain
TILa (PF12714, IPR025615): TILa domain
LRR_8 (PF13855, IPR001611): Leucine rich repeat
202 RAD21oncoprotein90.30623.233Rad21_Rec8 (PF04824, IPR006909): Conserved region of Rad21 / Rec8 like protein
Rad21_Rec8_N (PF04825, IPR006910): N terminus of Rad21 / Rec8 like protein
FAM176 (PF14851): FAM176 family
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
203 RAD54Binteractor31.0000SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
HDA2-3 (PF11496, IPR021006): Class II histone deacetylase complex subunits 2 and 3
204 RAD54Linteractor100Rad54_N (PF08658, IPR013967): Rad54 N terminal
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
205 RADILinteractor20144.773DIL (PF01843, IPR018444, SM01132): DIL domain
FHA (PF00498, IPR000253, SM00240): FHA domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
RA (PF00788, IPR000159, SM00314): Ras association (RalGDS/AF-6) domain
206 RAI1interactor30.6670.667Lin-8 (PF03353, IPR005020): Ras-mediated vulval-induction antagonist
DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360)
zf-HC5HC2H (PF13771): PHD-like zinc-binding domain
207 RBBP6oncoprotein50.4004.233DUF936 (PF06075, IPR010341): Plant protein of unknown function (DUF936)
DWNN (PF08783, IPR014891): DWNN domain
Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region
SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region
U-box (PF04564, IPR003613, SM00504): U-box domain
SBF2 (PF12335, IPR022096): Myotubularin protein
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
zf-CCHC_2 (PF13696, IPR025829): Zinc knuckle
AIF_C (PF14721, IPR029324): Apoptosis-inducing factor, mitochondrion-associated, C-term
CCDC106 (PF15794, IPR031591): Coiled-coil domain-containing protein 106
PRIMA1 (PF16101): Proline-rich membrane anchor 1
208 RBM15Binteractor21.0000CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
RRM_3 (PF08777, IPR014886): RNA binding motif
SPOC (PF07744, IPR012921): SPOC domain
MIP-T3 (PF10243): Microtubule-binding protein MIP-T3
DUF5094 (PF17015, IPR031519): Domain of unknown function (DUF5094)
209 RBM28interactor30.6670.667CDC27 (PF09507, IPR019038): DNA polymerase subunit Cdc27
DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754)
RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Nop25 (PF09805, IPR019186): Nucleolar protein 12 (25kDa)
RNA_pol_3_Rpc31 (PF11705, IPR024661): DNA-directed RNA polymerase III subunit Rpc31
Phage_TAC_13 (PF16459, IPR024410): Phage tail assembly chaperone, TAC
210 RBM42interactor21.0000RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PRIMA1 (PF16101): Proline-rich membrane anchor 1
211 RCL1interactor21.0000RTC (PF01137, IPR023797): RNA 3'-terminal phosphate cyclase
212 RGAG1interactor100GYD (PF08734, IPR014845): GYD domain
Retrotrans_gag (PF03732, IPR005162): Retrotransposon gag protein
213 RING1protein found in more fusions90.6076.200zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
214 RNASE4interactor21.0000RnaseA (PF00074, IPR023412, SM00092): Pancreatic ribonuclease
215 RNF2interactor440.099798.261zf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
216 RNMTinteractor21.0000Pox_MCEL (PF03291, IPR004971): mRNA capping enzyme
SH3BGR (PF04908, IPR006993): SH3-binding, glutamic acid-rich protein
217 RPL24interactor60.5334.686MAS20 (PF02064, IPR002056): MAS20 protein import receptor
Ribosomal_L24e (PF01246, IPR000988): Ribosomal protein L24e
218 RPS6KA4interactor30.33344.043Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
219 RRP9oncoprotein40.6671.333WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
HPS3_N (PF14761, IPR029437): Hermansky-Pudlak syndrome 3
220 RSPH9interactor30.6671.000Radial_spoke (PF04712, IPR006802): Radial spokehead-like protein
221 S100A14oncoprotein100S_100 (PF01023, IPR013787): S-100/ICaBP type calcium binding domain
222 SAMD1interactor40.5003.705CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510)
Pox_Ag35 (PF03286, IPR004966): Pox virus Ag35 surface protein
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
PRIMA1 (PF16101): Proline-rich membrane anchor 1
223 SCAPERinteractor100VIT1 (PF01988, IPR008217): VIT family
Atg14 (PF10186, IPR018791): Vacuolar sorting 38 and autophagy-related subunit 14
Nop25 (PF09805, IPR019186): Nucleolar protein 12 (25kDa)
CK1gamma_C (PF12605, IPR022247): Casein kinase 1 gamma C terminal
zf-met (PF12874): Zinc-finger of C2H2 type
SCAPER_N (PF16501, IPR032446): S phase cyclin A-associated protein in the endoplasmic reticulum
224 SCML2interactor31.0000MBT (PF02820, IPR004092, SM00561): mbt repeat
SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
SLED (PF12140, IPR021987): SLED domain
Ashwin (PF15323, IPR024887): Developmental protein
RBR (PF17208): RNA binding Region
225 SEH1Linteractor40.6672.352WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
Ge1_WD40 (PF16529, IPR032401): WD40 region of Ge1, enhancer of mRNA-decapping protein
226 SENP3interactor60.6005.333Nop53 (PF07767, IPR011687): Nop53 (60S ribosomal biogenesis)
Peptidase_C48 (PF02902, IPR003653): Ulp1 protease family, C-terminal catalytic domain
227 SERPINB12interactor100Serpin (PF00079, IPR023796, SM00093): Serpin (serine protease inhibitor)
228 SF3A2interactor70.38112.840Cytadhesin_P30 (PF07271, IPR009896): Cytadhesin P30/P32
PRP4 (PF08799, IPR014906): pre-mRNA processing factor 4 (PRP4) like
Totivirus_coat (PF05518, IPR008871): Totivirus coat protein
zf-met (PF12874): Zinc-finger of C2H2 type
ARL6IP6 (PF15062, IPR029383): Haemopoietic lineage transmembrane helix
SF3A2 (PF16835, IPR031781): Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11)
229 SH3BP1interactor100BAR (PF03114, IPR004148, SM00721): BAR domain
RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
PRCC (PF10253, IPR018800): Mitotic checkpoint regulator, MAD2B-interacting
230 SIRT5interactor100PNTB (PF02233, IPR012136): NAD(P) transhydrogenase beta subunit
SIR2 (PF02146, IPR003000): Sir2 family
TPP_enzyme_M (PF00205, IPR012000): Thiamine pyrophosphate enzyme, central domain
231 SLC25A17interactor100Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
232 SLC25A6interactor100Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
233 SLC35E1interactor100TPT (PF03151, IPR004853): Triose-phosphate Transporter family
234 SLCO4C1interactor100OATP (PF03137, IPR004156): Organic Anion Transporter Polypeptide (OATP) family
DUF2721 (PF11026, IPR021279): Protein of unknown function (DUF2721)
235 SMAD5interactor40.33346.259MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
236 SMCHD1suppressor40.8330.667Big_1 (PF02369, IPR003344, SM00634): Bacterial Ig-like domain (group 1)
SMC_hinge (PF06470, IPR010935, SM00968): SMC proteins Flexible Hinge Domain
HATPase_c_3 (PF13589): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
IFT20 (PF14931, IPR028172): Intraflagellar transport complex B, subunit 20
237 SNRPB2interactor50.6002.833DUF1027 (PF06265, IPR009370): Protein of unknown function (DUF1027)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
238 SNW1protein found in more fusions290.151291.757SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
SIR4_SID (PF16991, IPR031556): Sir4 SID domain
239 SP2interactor100zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
DUF3446 (PF11928, IPR021849): Domain of unknown function (DUF3446)
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
240 SPAG5interactor100CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
DUF1307 (PF06998, IPR009736): Protein of unknown function (DUF1307)
DUF1515 (PF07439, IPR010889): Protein of unknown function (DUF1515)
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
DUF3573 (PF12097, IPR021956): Protein of unknown function (DUF3573)
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
DUF4266 (PF14086, IPR025362): Domain of unknown function (DUF4266)
BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2
241 SPASTinteractor21.0000AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
MIT (PF04212, IPR007330, SM00745): MIT (microtubule interacting and transport) domain
TIP49 (PF06068, IPR010339): TIP49 C-terminus
Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain
AAA_14 (PF13173): AAA domain
P66_CC (PF16563, IPR032346): Coiled-coil and interaction region of P66A and P66B with MBD2
242 SPECC1oncoprotein21.0000CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
Fez1 (PF06818): Fez1
Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region
KxDL (PF10241, IPR019371): Uncharacterized conserved protein
TSNAXIP1_N (PF15739, IPR032755): Translin-associated factor X-interacting N-terminus
PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
HMMR_N (PF15905, IPR031787): Hyaluronan mediated motility receptor N-terminal
SHE3 (PF17078, IPR031398): SWI5-dependent HO expression protein 3
243 SPHK2interactor100DAGK_cat (PF00781, IPR001206, SM00046): Diacylglycerol kinase catalytic domain
244 SRBD1interactor21.0000S1 (PF00575, IPR003029, SM00316): S1 RNA binding domain
Tex_N (PF09371, IPR018974): Tex-like protein N-terminal domain
HHH_3 (PF12836): Helix-hairpin-helix motif
DLD (PF14878, IPR027999): Death-like domain of SPT6
Tex_YqgF (PF16921, IPR032639): Tex protein YqgF-like domain
245 SRCAPinteractor31.0000AT_hook (PF02178, IPR017956, SM00384): AT hook motif
HSA (PF07529, IPR014012, SM00573): HSA
RXT2_N (PF08595, IPR013904): RXT2-like, N-terminal
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
DBINO (PF13892, IPR020838): DNA-binding domain
PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal
246 SRPK1interactor90.30623.898FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid)
Pkinase (PF00069, IPR000719): Protein kinase domain
NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1
247 SRSF10interactor40.6671.667RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
248 STAT3suppressor80.048200.857SH2 (PF00017, IPR000980, SM00252): SH2 domain
STAT_alpha (PF01017, IPR013800): STAT protein, all-alpha domain
STAT_bind (PF02864, IPR013801): STAT protein, DNA binding domain
STAT_int (PF02865, IPR013799, SM00964): STAT protein, protein interaction domain
249 SUPT20Hinteractor50.30099.097Rubella_E2 (PF05749, IPR008821): Rubella membrane glycoprotein E2
DUF2076 (PF09849, IPR018648): Uncharacterized protein conserved in bacteria (DUF2076)
Spt20 (PF12090, IPR021950): Spt20 family
UL73_N (PF12522, IPR021003): Cytomegalovirus glycoprotein N terminal
250 TAAR2interactor1007tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
251 TADA2Binteractor30.6670.667SWIRM (PF04433, IPR007526): SWIRM domain
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
252 TAF5Linteractor50.6003.167TFIID_NTD2 (PF04494, IPR007582): WD40 associated region in TFIID subunit, NTD2 domain
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
253 TCEB3Binteractor100Elongin_A (PF06881, IPR010684): RNA polymerase II transcription factor SIII (Elongin) subunit A
Med26 (PF08711, IPR017923): TFIIS helical bundle-like domain
FAM176 (PF14851): FAM176 family
254 TECRinteractor31.0000Steroid_dh (PF02544, IPR001104): 3-oxo-5-alpha-steroid 4-dehydrogenase
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
255 TFAP2Asuppressor41.0000TF_AP-2 (PF03299, IPR013854): Transcription factor AP-2
CYYR1 (PF10873, IPR022640): Cysteine and tyrosine-rich protein 1
Peptidase_Prp (PF04327): Cysteine protease Prp
256 TMEM51interactor2039.240WBP-1 (PF11669, IPR021684): WW domain-binding protein 1
TMEM51 (PF15345, IPR029265): Transmembrane protein 51
257 TOMM34interactor21.0000TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
SHNi-TPR (PF10516, IPR019544): SHNi-TPR
TPR_12 (PF13424): Tetratricopeptide repeat
Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat
DUF4919 (PF16266, IPR032578): Domain of unknown function (DUF4919)
258 TP53suppressor440.085787.169DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
P53 (PF00870, IPR011615): P53 DNA-binding domain
P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
259 TP73suppressor70.33363.704P53 (PF00870, IPR011615): P53 DNA-binding domain
P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
260 TRIM25protein found in more fusions50.8330.803Fes1 (PF08609, IPR013918): Nucleotide exchange factor Fes1
Pox_Rif (PF03340, IPR005008): Poxvirus rifampicin resistance protein
SPRY (PF00622, IPR003877, SM00449): SPRY domain
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
PRY (PF13765, IPR006574, SM00589): SPRY-associated domain
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
261 TRIM3suppressor200C1_2 (PF03107, IPR004146): C1 domain
Filamin (PF00630, IPR017868): Filamin/ABP280 repeat
NHL (PF01436, IPR001258): NHL repeat
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
VCBS (PF13517): Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella
262 TRMT2Ainteractor100PCMT (PF01135, IPR000682): Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
tRNA_U5-meth_tr (PF05958, IPR010280): tRNA (Uracil-5-)-methyltransferase
Methyltransf_31 (PF13847, IPR025714): Methyltransferase domain
Hepar_II_III_N (PF16889, IPR031680): Heparinase II/III N-terminus
263 TSC2suppressor21.0000Rap_GAP (PF02145, IPR000331): Rap/ran-GAP
Tuberin (PF03542, IPR018515): Tuberin
DUF3384 (PF11864, IPR024584): Domain of unknown function (DUF3384)
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
264 TSPAN3interactor2014.840Hum_adeno_E3A (PF05393, IPR008652): Human adenovirus early E3A glycoprotein
Tetraspannin (PF00335, IPR018499): Tetraspanin family
265 TUBG1protein found in more fusions130.27346.199Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
266 TUBGCP2interactor50.7002.667Spc97_Spc98 (PF04130, IPR007259): Spc97 / Spc98 family
zf-Tim10_DDP (PF02953, IPR004217): Tim10/DDP family zinc finger
267 TUBGCP3interactor80.5009.466Spc97_Spc98 (PF04130, IPR007259): Spc97 / Spc98 family
268 UBE2D3interactor110.31187.889UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
269 UBE2L3interactor70.33356.744UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
270 UPF3Binteractor40.5003.000HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2)
POPLD (PF08170, IPR012590): POPLD (NUC188) domain
Smg4_UPF3 (PF03467, IPR005120): Smg-4/UPF3 family
TAF4 (PF05236, IPR007900): Transcription initiation factor TFIID component TAF4 family
DUF2098 (PF09871, IPR019209): Uncharacterized protein conserved in archaea (DUF2098)
Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family
DUF3464 (PF11947, IPR021855): Protein of unknown function (DUF3464)
271 USP10protein found in more fusions31.0000PAM2 (PF07145, IPR009818): Ataxin-2 C-terminal region
UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
YukD (PF08817, IPR024962): WXG100 protein secretion system (Wss), protein YukD
272 USP21interactor60.4006.000UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
273 USP9Xinteractor30.6671.172DUF1722 (PF08349, IPR013560): Protein of unknown function (DUF1722)
UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
Utp13 (PF08625, IPR013934): Utp13 specific WD40 associated domain
274 VPS33Binteractor21.0000Sec1 (PF00995, IPR001619): Sec1 family
275 WBP1interactor2039.240WBP-1 (PF11669, IPR021684): WW domain-binding protein 1
276 WBP11interactor60.4679.210BUD22 (PF09073, IPR015158): BUD22
Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region
SspB (PF04386, IPR007481): Stringent starvation protein B
Wbp11 (PF09429, IPR019007): WW domain binding protein 11
ABC_trans_N (PF14510, IPR029481): ABC-transporter extracellular N-terminal
277 WDR36interactor50.6003.500Utp21 (PF04192, IPR007319): Utp21 specific WD40 associated putative domain
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
WD40_like (PF17005, IPR031544): WD40-like domain
278 WIZinteractor60.5335.900AnfO_nitrog (PF09582, IPR014287): Iron only nitrogenase protein AnfO (AnfO_nitrog)
C1_2 (PF03107, IPR004146): C1 domain
Zn-ribbon_8 (PF09723, IPR013429, SM00834): Zinc ribbon domain
Enterotoxin_ST (PF02048, IPR001489): Heat-stable enterotoxin ST
zf-C2H2_4 (PF13894): C2H2-type zinc finger
279 XRN1interactor30.6671.000XRN_N (PF03159, IPR004859): XRN 5'-3' exonuclease N-terminus
280 YEATS4interactor70.47610.000YEATS (PF03366, IPR005033): YEATS family
SOGA (PF11365, IPR027881): Protein SOGA
281 YTHDF3interactor100Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
YTH (PF04146, IPR007275): YT521-B-like domain
282 ZBTB9interactor30.6671.000BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-C2HC_2 (PF13913): zinc-finger of a C2HC-type
PRIMA1 (PF16101): Proline-rich membrane anchor 1
283 ZC3H14interactor40.6672.000PWI (PF01480, IPR002483, SM00311): PWI domain
zf-CCCH_2 (PF14608): RNA-binding, Nab2-type zinc finger
284 ZC3H3interactor50.4005.333zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
CCDC24 (PF15669, IPR031367): Coiled-coil domain-containing protein 24 family
285 ZC3H7Binteractor100TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies)
TPR_8 (PF13181, IPR019734): Tetratricopeptide repeat
TPR_12 (PF13424): Tetratricopeptide repeat
286 ZCCHC17interactor21.0000S1 (PF00575, IPR003029, SM00316): S1 RNA binding domain
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
Coilin_N (PF15862, IPR031722): Coilin N-terminus
287 ZFP64oncoprotein30.6671.000zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain
zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger
zf-C2HE (PF16278, IPR032566): C2HE / C2H2 / C2HC zinc-binding finger
288 ZMAT4interactor100CTU2 (PF10288, IPR019407): Cytoplasmic tRNA 2-thiolation protein 2
DUF2946 (PF11162, IPR021333): Protein of unknown function (DUF2946)
zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding
zf-met (PF12874): Zinc-finger of C2H2 type
289 ZMYND8oncoprotein30.6671.000DUF1640 (PF07798, IPR024461): Protein of unknown function (DUF1640)
Mucin (PF01456, IPR000458): Mucin-like glycoprotein
PHD (PF00628, IPR019787, SM00249): PHD-finger
PWWP (PF00855, IPR000313, SM00293): PWWP domain
RNA_pol_Rbc25 (PF08292, IPR013238): RNA polymerase III subunit Rpc25
TCP (PF03634, IPR005333): TCP family transcription factor
zf-MYND (PF01753, IPR002893): MYND finger
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
DUF3544 (PF12064, IPR021931): Domain of unknown function (DUF3544)
CAML (PF14963, IPR016719): Calcium signal-modulating cyclophilin ligand
290 ZNF207interactor30.6671.000MCPVI (PF02993, IPR004243): Minor capsid protein VI
SMN (PF06003, IPR010304): Survival motor neuron protein (SMN)
zf-FCS (PF06467, IPR010507): MYM-type Zinc finger with FCS sequence motif
zf-C2H2_4 (PF13894): C2H2-type zinc finger
291 ZNF579interactor100SMN (PF06003, IPR010304): Survival motor neuron protein (SMN)
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger
Anti-TRAP (PF15777, IPR031538): Tryptophan RNA-binding attenuator protein inhibitory protein
PRIMA1 (PF16101): Proline-rich membrane anchor 1
zf-C2HE (PF16278, IPR032566): C2HE / C2H2 / C2HC zinc-binding finger
292 ZNF638interactor41.0000RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
zf-met (PF12874): Zinc-finger of C2H2 type
Ferlin_C (PF16165, IPR032362): Ferlin C-terminus
293 ZP3interactor21.0000MDMPI_C (PF07398, IPR010872): MDMPI C-terminal domain
Zona_pellucida (PF00100, IPR001507, SM00241): Zona pellucida-like domain
294 ZRANB3interactor100HNH (PF01844, IPR002711): HNH endonuclease
SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
zf-HIT (PF04438, IPR007529): HIT zinc finger
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
295 ZSWIM6interactor100SWIM (PF04434, IPR007527): SWIM zinc finger
RhlB (PF12300, IPR022077): ATP-dependent RNA helicase RhlB
DUF4413 (PF14372, IPR025525): Domain of unknown function (DUF4413)
296 ZZZ3interactor40.6672.000Cript (PF10235, IPR019367): Microtubule-associated protein CRIPT
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type

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