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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins CXCR1, PLPP4 (from a repository: Tue May 2 10:48:34 2017)

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)7
The number (and %) of the onco-proteins4 (57.14 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)10 (47.62 %)
The number (and %) of affected PPIs6 (60.00 %)
The number of possible different fusions2
PPI diameter2
PPI radiusinf
The average degree of PPI1.714
Assortativity coefficient-0.4472
The network average Clustering coefficient0.300
The number (and %) of a zero Clustering coefficients4 (57.14 %)
The number (and %) of a zero Betweenness Centrality6 (85.71 %)


List of the fusions

PPI for parental proteins: PLPP4,CXCR1 All fusions
Proteins found in more fusions UBE2C (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Domains (Pfam, InterPro, SMART): description
1 PLPP4parental protein100Colicin_V (PF02674, IPR003825): Colicin V production protein
DUF975 (PF06161, IPR010380): Protein of unknown function (DUF975)
PAP2 (PF01569, IPR000326, SM00014): PAP2 superfamily
2 CXCR1parental protein50.10018.0007tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
DUF2909 (PF11137, IPR021313): Protein of unknown function (DUF2909)
3 CDK1oncoprotein200Pkinase (PF00069, IPR000719): Protein kinase domain
4 GNAI2oncoprotein100G-alpha (PF00503, IPR001019, SM00275): G-protein alpha subunit
5 PDCD6IPinteractor31.0000BRO1 (PF03097, IPR004328, SM01041): BRO1-like domain
MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
ALIX_LYPXL_bnd (PF13949, IPR025304): ALIX V-shaped domain binding to HIV
6 TUBA1Aoncoprotein21.0000Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
7 UBE2Concoprotein200UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme

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