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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins SMUG1, ANTXRL (from a repository: Fri Jun 1 09:10:14 2018)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)6
The number (and %) of the onco-proteins2 (33.33 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)8 (53.33 %)
The number (and %) of affected PPIs4 (50.00 %)
The number of possible different fusions3
PPI diameter2
PPI radiusinf
The average degree of PPI1.667
Assortativity coefficient-0.4082
The network average Clustering coefficient0.361
The number (and %) of a zero Clustering coefficients3 (50.00 %)
The number (and %) of a zero Betweenness Centrality5 (83.33 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: ANTXRL,SMUG1 All fusions
Proteins found in more fusions RBPMS (see 2 fusions); VAC14 (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 ANTXRLinteractor000Anth_Ig (PF05587, IPR008400): Anthrax receptor extracellular domain
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
VWA (PF00092, IPR002035, SM00327): von Willebrand factor type A domain
2 SMUG1parental protein40.16710.000UDG (PF03167, IPR005122, SM00986): Uracil DNA glycosylase superfamily
3 RBPMSprotein found in more fusions31.0000RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
4 TRIP13interactor31.0000AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
5 UNGinteractor100UDG (PF03167, IPR005122, SM00986): Uracil DNA glycosylase superfamily
6 VAC14oncoprotein200TAF6_C (PF07571, IPR011442): TAF6 C-terminal HEAT repeat domain
HEAT (PF02985, IPR000357): HEAT repeat
Vac14_Fig4_bd (PF11916, IPR021841): Vacuolar protein 14 C-terminal Fig4p binding
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region

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