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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins EFNA5, IQGAP1 (from a repository: Thu Feb 16 04:13:48 2017)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)257
The number (and %) of the onco-proteins83 (32.30 %)
The number (and %) of the tumor suppressors32 (12.45 %)
Total number of binary PPIs (saturation %)3089 (9.39 %)
The number (and %) of affected PPIs256 (8.29 %)
The number of possible different fusions47
PPI diameter4
PPI radius2
The average degree of PPI23.455
Assortativity coefficient-0.2804
The network average Clustering coefficient0.504
The number (and %) of a zero Clustering coefficients7 (2.72 %)
The number (and %) of a zero Betweenness Centrality19 (7.39 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: IQGAP1,EFNA5 All fusions
Proteins found in more fusions TPM2/MYH9 (see 1 fusions); U2AF2 (see 2 fusions); ACTG1/ACTB (see 1 fusions); WHSC1 (see 1 fusions); FLNA/PPP1R9B (see 1 fusions); GRB2 (see 1 fusions); TPM2 (see 1 fusions); AIMP2 (see 1 fusions); SORBS2 (see 4 fusions); CTTN (see 1 fusions); RPA1 (see 1 fusions); GRIP1 (see 2 fusions); SNW1 (see 1 fusions); PTBP1 (see 1 fusions); TPM1 (see 2 fusions); VCP (see 4 fusions); TPM2/TPM3 (see 1 fusions); HSP90AB1 (see 1 fusions); OFD1 (see 1 fusions); NTRK1/TPM3 (see 3 fusions); EZR (see 2 fusions); CLINT1 (see 2 fusions); SHC1 (see 1 fusions); PTK2 (see 2 fusions); STAU1 (see 2 fusions); EPS15 (see 1 fusions); MAPK1 (see 1 fusions); CBL (see 1 fusions); CUL7 (see 2 fusions); PPME1 (see 1 fusions); RAC1 (see 1 fusions); MYC (see 1 fusions); CDH1 (see 3 fusions); ACTB (see 3 fusions); ACTG1 (see 4 fusions); PEX14 (see 1 fusions); LRRK2 (see 1 fusions); TP53 (see 3 fusions); AP2M1 (see 3 fusions); TPM2/TPM1 (see 1 fusions); ACTN1 (see 3 fusions); TPM3 (see 2 fusions); MAPK14 (see 1 fusions); MCM2 (see 1 fusions); BRAF (see 3 fusions); RPTOR (see 3 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 IQGAP1parental protein2500.08729529.534CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
DUF87 (PF01935, IPR002789): Domain of unknown function DUF87
IDEAL (PF08858, IPR014957, SM00914): IDEAL domain
IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase
RasGAP_C (PF03836, IPR000593): RasGAP C-terminus
WW (PF00397, IPR001202, SM00456): WW domain
2 EFNA5parental protein60.067536.779Ephrin (PF00812, IPR001799): Ephrin
3 ABCE1interactor250.29091.553ABC_tran (PF00005, IPR003439): ABC transporter
Fer4 (PF00037, IPR001450): 4Fe-4S binding domain
RLI (PF04068, IPR007209): Possible Fer4-like domain in RNase L inhibitor, RLI
SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
Fer4_7 (PF12838, IPR001450): 4Fe-4S dicluster domain
AAA_29 (PF13555): P-loop containing region of AAA domain
4 ABLIM1interactor160.7084.038LIM (PF00412, IPR001781, SM00132): LIM domain
VHP (PF02209, IPR003128, SM00153): Villin headpiece domain
zf-dskA_traR (PF01258, IPR000962): Prokaryotic dksA/traR C4-type zinc finger
DUF2175 (PF09943, IPR018686): Uncharacterized protein conserved in archaea (DUF2175)
AbLIM_anchor (PF16182, IPR032402): Putative adherens-junction anchoring region of AbLIM
5 ACTBoncoprotein590.266525.159Actin (PF00022, IPR004000, SM00268): Actin
6 ACTG1protein found in more fusions410.369149.879Actin (PF00022, IPR004000, SM00268): Actin
7 ACTN1protein found in more fusions290.44758.890CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
Dak2 (PF02734, IPR004007, SM01120): DAK2 domain
EFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand
Spectrin (PF00435, IPR002017): Spectrin repeat
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
Uds1 (PF15456, IPR029191): Up-regulated During Septation
8 ACTN4interactor370.390100.630CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
EFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand
Spectrin (PF00435, IPR002017): Spectrin repeat
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
Uds1 (PF15456, IPR029191): Up-regulated During Septation
9 ACTR2interactor480.395171.876Actin (PF00022, IPR004000, SM00268): Actin
10 ACTR3interactor310.54434.789Actin (PF00022, IPR004000, SM00268): Actin
11 ADD1interactor180.43116.515Aldolase_II (PF00596, IPR001303, SM01007): Class II Aldolase and Adducin N-terminal domain
CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
12 AFAP1interactor160.7717.408PH (PF00169, IPR001849, SM00233): PH domain
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
Enkurin (PF13864, IPR027012): Calmodulin-binding
13 AIMP1suppressor130.56410.669DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region
PRP1_N (PF06424, IPR010491): PRP1 splicing factor, N-terminal
tRNA_bind (PF01588, IPR002547): Putative tRNA binding domain
14 AIMP2suppressor150.50519.353GST_C_2 (PF13410): Glutathione S-transferase, C-terminal domain
GST_C_3 (PF14497, IPR004046): Glutathione S-transferase, C-terminal domain
AIMP2_LysRS_bd (PF16780, IPR031889): AIMP2 lysyl-tRNA synthetase binding domain
15 AKAP2interactor120.8480.627DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
AKAP2_C (PF15304, IPR029304): A-kinase anchor protein 2 C-terminus
16 AKAP5interactor30.6670.691WSK (PF03832, IPR001573): WSK motif
17 AKT1oncoprotein190.30144.165PH (PF00169, IPR001849, SM00233): PH domain
Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
18 ANXA2interactor310.42247.673Annexin (PF00191, IPR018502, SM00335): Annexin
19 ANXA5oncoprotein100.5338.595Annexin (PF00191, IPR018502, SM00335): Annexin
20 AP2A1interactor330.54735.655Adaptin_N (PF01602, IPR002553): Adaptin N terminal region
Alpha_adaptin_C (PF02296, IPR003164): Alpha adaptin AP2, C-terminal domain
Alpha_adaptinC2 (PF02883, IPR008152, SM00809): Adaptin C-terminal domain
HEAT_2 (PF13646): HEAT repeats
21 AP2A2interactor200.57414.869Adaptin_N (PF01602, IPR002553): Adaptin N terminal region
Alpha_adaptin_C (PF02296, IPR003164): Alpha adaptin AP2, C-terminal domain
Alpha_adaptinC2 (PF02883, IPR008152, SM00809): Adaptin C-terminal domain
HEAT_2 (PF13646): HEAT repeats
22 AP2M1protein found in more fusions350.444135.110Adap_comp_sub (PF00928, IPR008968): Adaptor complexes medium subunit family
Clat_adaptor_s (PF01217, IPR022775): Clathrin adaptor complex small chain
23 ARF6oncoprotein50.6000.423Arf (PF00025, IPR006689, SM00177): ADP-ribosylation factor family
24 ARHGAP11Ainteractor120.8640.939RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
25 ARHGAP21interactor120.9850.061PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
MAJIN (PF15077, IPR027816): Membrane-anchored junction protein
PH_9 (PF15410): Pleckstrin homology domain
26 ARHGEF17interactor70.7140.737DUF1351 (PF07083, IPR009785): Protein of unknown function (DUF1351)
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
BBS2_Mid (PF14783, IPR029429): Ciliary BBSome complex subunit 2, middle region
27 ARPC2interactor270.52139.720P34-Arc (PF04045, IPR007188): Arp2/3 complex, 34 kD subunit p34-Arc
Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain
28 ARPC3interactor270.55837.407P21-Arc (PF04062, IPR007204): ARP2/3 complex ARPC3 (21 kDa) subunit
29 ARPC4interactor260.53527.958ARPC4 (PF05856, IPR008384): ARP2/3 complex 20 kDa subunit (ARPC4)
30 ARPC5Linteractor200.7479.248P16-Arc (PF04699, IPR006789): ARP2/3 complex 16 kDa subunit (p16-Arc)
31 ASCC3interactor60.4001.787DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
PhoH (PF02562, IPR003714): PhoH-like protein
Sec63 (PF02889, IPR004179, SM00973): Sec63 Brl domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
32 BASP1suppressor130.8331.832BASP1 (PF05466, IPR008408): Brain acid soluble protein 1 (BASP1 protein)
33 BMP2Kinteractor190.8013.495Pkinase (PF00069, IPR000719): Protein kinase domain
TCP (PF03634, IPR005333): TCP family transcription factor
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
EOS1 (PF12326, IPR021100): N-glycosylation protein
BMP2K_C (PF15282, IPR028182): BMP-2-inducible protein kinase C-terminus
PNRC (PF15365, IPR028322): Proline-rich nuclear receptor coactivator
FAM60A (PF15396, IPR026065): Protein Family FAM60A
34 BRAFoncoprotein120.40020.711Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
RBD (PF02196, IPR003116, SM00455): Raf-like Ras-binding domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
35 CALM1interactor290.300155.250EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
36 CAMK2Ginteractor70.7143.113CaMKII_AD (PF08332, IPR013543): Calcium/calmodulin dependent protein kinase II association domain
Pkinase (PF00069, IPR000719): Protein kinase domain
37 CAPZA2interactor1060.2021233.773F-actin_cap_A (PF01267, IPR002189): F-actin capping protein alpha subunit
38 CAPZBinteractor310.48840.740Cytochrom_B562 (PF07361, IPR009155): Cytochrome b562
F_actin_cap_B (PF01115, IPR001698): F-actin capping protein, beta subunit
39 CBLsuppressor340.263391.561Cbl_N (PF02262, IPR003153): CBL proto-oncogene N-terminal domain 1
Cbl_N2 (PF02761, IPR014741): CBL proto-oncogene N-terminus, EF hand-like domain
Cbl_N3 (PF02762, IPR014742): CBL proto-oncogene N-terminus, SH2-like domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
Prok-RING_4 (PF14447): Prokaryotic RING finger family 4
zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain
40 CCAR2suppressor200.36857.146DREPP (PF05558, IPR008469): DREPP plasma membrane polypeptide
IncA (PF04156, IPR007285): IncA protein
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
DBC1 (PF14443, IPR025954, SM01122): DBC1
S1-like (PF14444, IPR025223): S1-like
41 CCDC8interactor640.175711.084Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
PNMA (PF14893, IPR026523): PNMA
42 CCT2interactor300.368107.890Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
43 CD44suppressor110.5826.785VP4_2 (PF08935, IPR015031): Viral protein VP4 subunit
Xlink (PF00193, IPR000538, SM00445): Extracellular link domain
S36_mt (PF10937, IPR020373): Ribosomal protein S36, mitochondrial
44 CDC42oncoprotein210.19595.287Ras (PF00071, IPR001806, SM00173): Ras family
45 CDC5Linteractor430.316199.671OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat
Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component
Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain
46 CDH1suppressor140.24421.558Cadherin_C (PF01049, IPR000233): Cadherin cytoplasmic region
Cadherin_pro (PF08758, IPR014868, SM01055): Cadherin prodomain like
Cadherin (PF00028, IPR002126, SM00112): Cadherin domain
47 CDK2suppressor840.210955.289Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family
Pkinase (PF00069, IPR000719): Protein kinase domain
48 CDK4oncoprotein110.45511.182Pkinase (PF00069, IPR000719): Protein kinase domain
49 CDKN2Asuppressor190.345141.415Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
50 CEP57interactor60.4675.509Cep57_MT_bd (PF06657, IPR024957): Centrosome microtubule-binding domain of Cep57
Tup_N (PF08581, IPR013890): Tup N-terminal
CENP-Q (PF13094, IPR025212): CENP-Q, a CENPA-CAD centromere complex subunit
Cep57_CLD (PF14073, IPR025913): Centrosome localisation domain of Cep57
TRIQK (PF15168, IPR024842): Triple QxxK/R motif-containing protein family
51 CEP76interactor60.5332.721Transglut_core (PF01841, IPR002931, SM00460): Transglutaminase-like superfamily
CEP76-C2 (PF15627, IPR028926): CEP76 C2 domain
52 CEPT1interactor30.3332.367CDP-OH_P_transf (PF01066, IPR000462): CDP-alcohol phosphatidyltransferase
53 CFL1interactor310.46962.141Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein
54 CFL2interactor160.9330.738Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein
55 CGNinteractor100.5783.335DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
Filament (PF00038, IPR001664): Intermediate filament protein
Laminin_II (PF06009, IPR010307): Laminin Domain II
Myosin_tail_1 (PF01576, IPR002928): Myosin tail
DUF4559 (PF15112, IPR027897): Domain of unknown function (DUF4559)
Leu_zip (PF15294): Leucine zipper
56 CLIC1interactor140.30810.259GST_N_2 (PF13409, IPR004045): Glutathione S-transferase, N-terminal domain
GST_C_2 (PF13410): Glutathione S-transferase, C-terminal domain
57 CLINT1protein found in more fusions250.64516.488ENTH (PF01417, IPR001026, SM00273): ENTH domain
58 CLIP1oncoprotein40.5001.086ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
CAP_GLY (PF01302, IPR000938, SM01052): CAP-Gly domain
CP12 (PF02672, IPR003823, SM01093): CP12 domain
DASH_Hsk3 (PF08227, IPR013183): DASH complex subunit Hsk3 like
DUF848 (PF05852, IPR008566): Gammaherpesvirus protein of unknown function (DUF848)
FlaC_arch (PF05377, IPR008039): Flagella accessory protein C (FlaC)
FliJ (PF02050, IPR012823): Flagellar FliJ protein
Lectin_N (PF03954, IPR005640): Hepatic lectin, N-terminal domain
SlyX (PF04102, IPR007236): SlyX
ApoO (PF09769, IPR019166): Apolipoprotein O
Ax_dynein_light (PF10211, IPR019347): Axonemal dynein light chain
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
Leu_zip (PF15294): Leucine zipper
CLIP1_ZNF (PF16641, IPR032108): CLIP1 zinc knuckle
PKcGMP_CC (PF16808, IPR031831): Coiled-coil N-terminus of cGMP-dependent protein kinase
59 CLTAinteractor250.60716.021Clathrin_lg_ch (PF01086, IPR000996): Clathrin light chain
60 CLTBinteractor280.65929.500Clathrin_lg_ch (PF01086, IPR000996): Clathrin light chain
61 CLTConcoprotein600.295476.478Clathrin-link (PF09268, IPR015348): Clathrin, heavy-chain linker
Clathrin_propel (PF01394, IPR022365): Clathrin propeller repeat
Clathrin (PF00637, IPR000547, SM00299): Region in Clathrin and VPS
Clathrin_H_link (PF13838): Clathrin-H-link
62 COBLinteractor170.7065.755CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
Cobl (PF09469, IPR019025): Cordon-bleu ubiquitin-like domain
RBD (PF02196, IPR003116, SM00455): Raf-like Ras-binding domain
WH2 (PF02205, IPR003124, SM00246): WH2 motif
PRIMA1 (PF16101): Proline-rich membrane anchor 1
63 CORO1Binteractor200.71621.072DUF1899 (PF08953, IPR015048, SM01166): Domain of unknown function (DUF1899)
Trimer_CC (PF08954, IPR015049, SM01167): Trimerisation motif
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
WD40_4 (PF16300): Type of WD40 repeat
64 CORO1Concoprotein340.43988.091DUF1899 (PF08953, IPR015048, SM01166): Domain of unknown function (DUF1899)
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
WD40_4 (PF16300): Type of WD40 repeat
65 CORO2Aoncoprotein110.8552.788Calpain_III (PF01067, IPR022682, SM00720): Calpain large subunit, domain III
DUF1899 (PF08953, IPR015048, SM01166): Domain of unknown function (DUF1899)
SGL (PF08450, IPR013658): SMP-30/Gluconolaconase/LRE-like region
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
WD40_4 (PF16300): Type of WD40 repeat
66 CTNNB1oncoprotein230.249253.350Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361)
HEAT_EZ (PF13513): HEAT-like repeat
67 CTTNoncoprotein300.50557.026FadA (PF09403, IPR018543): Adhesion protein FadA
HS1_rep (PF02218, IPR003134): Repeat in HS1/Cortactin
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
68 CUL7protein found in more fusions540.263282.681ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10)
Cullin (PF00888, IPR001373, SM00182): Cullin family
DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918)
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7
69 CYBBinteractor21.0000FAD_binding_8 (PF08022, IPR013112): FAD-binding domain
Ferric_reduct (PF01794, IPR013130): Ferric reductase like transmembrane component
NAD_binding_6 (PF08030, IPR013121): Ferric reductase NAD binding domain
70 CYBRD1interactor91.0000Cytochrom_B561 (PF03188, IPR004877): Eukaryotic cytochrome b561
Phage_holin_3_6 (PF07332, IPR009937): Putative Actinobacterial Holin-X, holin superfamily III
71 CYP1A1oncoprotein21.0000p450 (PF00067, IPR001128): Cytochrome P450
72 DAB2suppressor230.61743.813PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID)
zf-C2H2_assoc3 (PF16637): Putative zinc-finger between two C2H2 zinc-fingers on Patz
73 DAPK3suppressor140.7564.575OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
Pkinase (PF00069, IPR000719): Protein kinase domain
PspA_IM30 (PF04012, IPR007157): PspA/IM30 family
74 DBN1oncoprotein1050.2111185.092Pinin_SDK_memA (PF04696, IPR006786): pinin/SDK/memA/ protein conserved region
Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein
CAF-1_p150 (PF11600): Chromatin assembly factor 1 complex p150 subunit, N-terminal
MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
75 DDX19Binteractor50.7000.654DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
76 DIAPH1interactor80.4643.238APG6 (PF04111, IPR007243): Autophagy protein Apg6
Drf_DAD (PF06345, IPR010465): DRF Autoregulatory Domain
Drf_FH1 (PF06346, IPR009408): Formin Homology Region 1
Drf_FH3 (PF06367, IPR010472, SM01139): Diaphanous FH3 Domain
Drf_GBD (PF06371, IPR010473, SM01140): Diaphanous GTPase-binding Domain
FH2 (PF02181, IPR015425, SM00498): Formin Homology 2 Domain
Glucan_synthase (PF02364, IPR003440): 1,3-beta-glucan synthase component
Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
77 DNAJA1interactor240.308100.138DnaJ (PF00226, IPR001623, SM00271): DnaJ domain
DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
78 DSG1interactor70.6672.377Cadherin_C (PF01049, IPR000233): Cadherin cytoplasmic region
Cadherin (PF00028, IPR002126, SM00112): Cadherin domain
Cadherin_3 (PF16184): Cadherin-like
79 DSG2oncoprotein140.6813.912BAT2_N (PF07001, IPR009738): BAT2 N-terminus
Cadherin_C (PF01049, IPR000233): Cadherin cytoplasmic region
Cadherin (PF00028, IPR002126, SM00112): Cadherin domain
Cadherin_3 (PF16184): Cadherin-like
80 DSToncoprotein150.5525.969CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
ZYG-11_interact (PF05884, IPR008574): Interactor of ZYG-11
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
GAS2 (PF02187, IPR003108, SM00243): Growth-Arrest-Specific Protein 2 Domain
Laminin_II (PF06009, IPR010307): Laminin Domain II
Mod_r (PF07200, IPR009851): Modifier of rudimentary (Mod(r)) protein
Phasin (PF05597, IPR008769): Poly(hydroxyalcanoate) granule associated protein (phasin)
Spectrin (PF00435, IPR002017): Spectrin repeat
Nbl1_Borealin_N (PF10444, IPR018851): Nbl1 / Borealin N terminal
XhlA (PF10779, IPR019715): Haemolysin XhlA
zf-C4H2 (PF10146, IPR018482): Zinc finger-containing protein
Plectin (PF00681, IPR001101, SM00250): Plectin repeat
DUF3446 (PF11928, IPR021849): Domain of unknown function (DUF3446)
FTA4 (PF13093, IPR025207): Kinetochore complex Fta4 of Sim4 subunit, or CENP-50
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
DUF4404 (PF14357, IPR025516): Domain of unknown function (DUF4404)
NYD-SP28 (PF14772): Sperm tail
Muted (PF14942, IPR017243): Organelle biogenesis, Muted-like protein
81 DVL2interactor110.4227.719DEP (PF00610, IPR000591, SM00049): Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)
Dishevelled (PF02377, IPR003351): Dishevelled specific domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
DIX (PF00778, IPR001158, SM00021): DIX domain
Dsh_C (PF12316, IPR024580): Segment polarity protein dishevelled (Dsh) C terminal
82 ECH1interactor21.0000ECH_1 (PF00378, IPR001753): Enoyl-CoA hydratase/isomerase
83 EEF1E1suppressor120.5918.146GST_C (PF00043, IPR004046): Glutathione S-transferase, C-terminal domain
84 EID1interactor21.0000NA
85 EIF2S3interactor100.6004.147eIF2_C (PF09173, IPR015256): Initiation factor eIF2 gamma, C terminal
GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
86 EIF4G1oncoprotein170.44120.196DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180)
MA3 (PF02847, IPR003891, SM00544): MA3 domain
MIF4G (PF02854, IPR003890, SM00543): MIF4G domain
Neisseria_TspB (PF05616, IPR008708): Neisseria meningitidis TspB protein
W2 (PF02020, IPR003307, SM00515): eIF4-gamma/eIF5/eIF2-epsilon
87 EPHA3suppressor40.50019.582EGF_2 (PF07974, IPR013111): EGF-like domain
EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Ephrin_rec_like (PF07699, IPR011641): Putative ephrin-receptor like
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
Ephrin_lbd (PF01404, IPR001090, SM00615): Ephrin receptor ligand binding domain
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
EphA2_TM (PF14575, IPR027936): Ephrin type-A receptor 2 transmembrane domain
88 EPHA7oncoprotein100EGF_2 (PF07974, IPR013111): EGF-like domain
EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Ephrin_rec_like (PF07699, IPR011641): Putative ephrin-receptor like
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
Ephrin_lbd (PF01404, IPR001090, SM00615): Ephrin receptor ligand binding domain
EphA2_TM (PF14575, IPR027936): Ephrin type-A receptor 2 transmembrane domain
89 EPHB1interactor30.33325.070EGF_2 (PF07974, IPR013111): EGF-like domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Ephrin_rec_like (PF07699, IPR011641): Putative ephrin-receptor like
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
Ephrin_lbd (PF01404, IPR001090, SM00615): Ephrin receptor ligand binding domain
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
EphA2_TM (PF14575, IPR027936): Ephrin type-A receptor 2 transmembrane domain
90 EPS15oncoprotein270.60625.528Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif
DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391)
EF-hand_4 (PF12763, IPR000261): Cytoskeletal-regulatory complex EF hand
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
91 EZRprotein found in more fusions180.34632.275DUF106 (PF01956, IPR002809): Integral membrane protein DUF106
ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain
FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
92 FBXO25suppressor240.29362.275Elongin_A (PF06881, IPR010684): RNA polymerase II transcription factor SIII (Elongin) subunit A
93 FLIIoncoprotein210.543242.988Gelsolin (PF00626, IPR007123): Gelsolin repeat
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
94 FLNAsuppressor1130.2271523.943CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
Filamin (PF00630, IPR017868): Filamin/ABP280 repeat
95 FLNBoncoprotein260.42539.286CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
Filamin (PF00630, IPR017868): Filamin/ABP280 repeat
PapC_N (PF13954, IPR025885): PapC N-terminal domain
96 FN1oncoprotein670.204687.862fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain
fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
97 GAPVD1interactor70.4763.695RasGAP (PF00616, IPR001936, SM00323): GTPase-activator protein for Ras-like GTPase
VPS9 (PF02204, IPR003123, SM00167): Vacuolar sorting protein 9 (VPS9) domain
98 GAS2L1interactor60.6671.325CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
GAS2 (PF02187, IPR003108, SM00243): Growth-Arrest-Specific Protein 2 Domain
SPX (PF03105, IPR004331): SPX domain
99 GGPS1interactor200polyprenyl_synt (PF00348, IPR000092): Polyprenyl synthetase
100 GOLIM4interactor30.6670.154Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP)
DDRGK (PF09756, IPR019153, SM01128): DDRGK domain
EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region
DUF3410 (PF11890, IPR024531): Domain of unknown function (DUF3410)
DUF3584 (PF12128, IPR021979): Protein of unknown function (DUF3584)
DUF4525 (PF15027, IPR027833): Domain of unknown function (DUF4525)
101 GRB2oncoprotein500.292652.906SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
DUF5093 (PF17011, IPR031533): Domain of unknown function (DUF5093)
102 GRIP1protein found in more fusions5027.820PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
103 GSNsuppressor270.385107.572Gelsolin (PF00626, IPR007123): Gelsolin repeat
104 GTSE1interactor230.54941.197GTSE1_N (PF15259, IPR032768): G-2 and S-phase expressed 1
105 HNRNPA1interactor460.374218.184RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1
106 HOXB5interactor30.6670.222DUF739 (PF05339, IPR008003): Protein of unknown function (DUF739)
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
107 HSP90AB1oncoprotein460.314249.230HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
108 HSPA5oncoprotein500.292337.965HSP70 (PF00012, IPR013126): Hsp70 protein
109 INF2interactor170.6916.207Drf_FH1 (PF06346, IPR009408): Formin Homology Region 1
Drf_FH3 (PF06367, IPR010472, SM01139): Diaphanous FH3 Domain
Drf_GBD (PF06371, IPR010473, SM01140): Diaphanous GTPase-binding Domain
FH2 (PF02181, IPR015425, SM00498): Formin Homology 2 Domain
WH2 (PF02205, IPR003124, SM00246): WH2 motif
Caskin-Pro-rich (PF16907): Proline rich region of Caskin proteins
110 INPPL1oncoprotein130.6546.104Exo_endo_phos (PF03372, IPR005135): Endonuclease/Exonuclease/phosphatase family
SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
SH2 (PF00017, IPR000980, SM00252): SH2 domain
111 ISG15suppressor220.27736.875ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
112 ITGA4interactor460.266253.170FG-GAP (PF01839, IPR013517): FG-GAP repeat
Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region
Integrin_alpha2 (PF08441, IPR013649): Integrin alpha
113 KBTBD7interactor60.6002.021BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Kelch_2 (PF07646, IPR011498): Kelch motif
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
Kelch_4 (PF13418): Galactose oxidase, central domain
Kelch_6 (PF13964): Kelch motif
114 KCTD3interactor100BTB_2 (PF02214, IPR003131): BTB/POZ domain
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
115 KDRoncoprotein90.44412.834Ehrlichia_rpt (PF09528, IPR019048): Ehrlichia tandem repeat (Ehrlichia_rpt)
Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Ig_2 (PF13895, IPR007110): Immunoglobulin domain
Ig_3 (PF13927): Immunoglobulin domain
Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain
Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
116 LGR4interactor140.26929.0217tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
LRRNT (PF01462, IPR000372, SM00013): Leucine rich repeat N-terminal domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
117 LIMA1suppressor990.2311035.957LIM (PF00412, IPR001781, SM00132): LIM domain
ROKNT (PF08067, IPR012987): ROKNT (NUC014) domain
118 LIMCH1interactor110.6181.473LIM (PF00412, IPR001781, SM00132): LIM domain
MAS20 (PF02064, IPR002056): MAS20 protein import receptor
DUF3435 (PF11917, IPR021842): Protein of unknown function (DUF3435)
DUF4757 (PF15949, IPR031865): Domain of unknown function (DUF4757)
119 LMO7oncoprotein170.5077.658CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764)
LIM (PF00412, IPR001781, SM00132): LIM domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
DUF2072 (PF09845, IPR018645): Zn-ribbon containing protein
AAA_23 (PF13476): AAA domain
DUF4757 (PF15949, IPR031865): Domain of unknown function (DUF4757)
120 LRP6interactor40.5002.286Ldl_recept_a (PF00057, IPR002172, SM00192): Low-density lipoprotein receptor domain class A
Ldl_recept_b (PF00058, IPR000033, SM00135): Low-density lipoprotein receptor repeat class B
FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site
DUF5050 (PF16472, IPR032485): Domain of unknown function (DUF5050)
121 LRRC47interactor80.5007.980B3_4 (PF03483, IPR005146, SM00873): B3/4 domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
122 LRRFIP1oncoprotein90.5288.573CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
Rxt3 (PF08642, IPR013951): Histone deacetylation protein Rxt3
LRRFIP (PF09738, IPR019139): LRRFIP family
RP-C_C (PF11800, IPR021760): Replication protein C C-terminal region
Coilin_N (PF15862, IPR031722): Coilin N-terminus
123 LRRFIP2interactor110.9450.139TACC (PF05010, IPR007707): Transforming acidic coiled-coil-containing protein (TACC)
LRRFIP (PF09738, IPR019139): LRRFIP family
124 LRRK2oncoprotein340.242150.924Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain
DUF1043 (PF06295, IPR009386): Protein of unknown function (DUF1043)
T2SSE (PF00437, IPR001482): Type II/IV secretion system protein
Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase
Pkinase (PF00069, IPR000719): Protein kinase domain
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
PQQ_2 (PF13360, IPR002372): PQQ-like domain
LRR_8 (PF13855, IPR001611): Leucine rich repeat
COR (PF16095, IPR032171): C-terminal of Roc, COR, domain
125 LUZP1interactor150.7816.362Trimer_CC (PF08954, IPR015049, SM01167): Trimerisation motif
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
EMP24_GP25L (PF01105, IPR009038): emp24/gp25L/p24 family/GOLD
Fzo_mitofusin (PF04799, IPR006884): fzo-like conserved region
MerR-DNA-bind (PF09278, IPR015358): MerR, DNA binding
Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
TMA7 (PF09072, IPR015157): Translation machinery associated TMA7
HD_assoc (PF13286, IPR026875): Phosphohydrolase-associated domain
DUF4298 (PF14131, IPR025384): Domain of unknown function (DUF4298)
PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
126 LZTS2suppressor120.33322.461CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
DUF1127 (PF06568, IPR009506): Domain of unknown function (DUF1127)
Fez1 (PF06818): Fez1
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
DUF4250 (PF14056, IPR025346): Domain of unknown function (DUF4250)
127 MAGEA4interactor100MAGE (PF01454, IPR002190): MAGE family
MAGE_N (PF12440, IPR021072): Melanoma associated antigen family N terminal
128 MAP2K1oncoprotein90.6079.467Pkinase (PF00069, IPR000719): Protein kinase domain
DUF3216 (PF11505, IPR023108): Protein of unknown function (DUF3216)
129 MAP2K2interactor80.5716.667Pkinase (PF00069, IPR000719): Protein kinase domain
CAMSAP_CC1 (PF17095, IPR031372): Spectrin-binding region of Ca2+-Calmodulin
130 MAPK1oncoprotein180.34648.704Pkinase (PF00069, IPR000719): Protein kinase domain
131 MAPK14oncoprotein150.38520.477Pkinase (PF00069, IPR000719): Protein kinase domain
132 MAPK3oncoprotein130.42423.208Pkinase (PF00069, IPR000719): Protein kinase domain
133 MCM2oncoprotein610.272468.493AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA)
MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
134 MEN1suppressor70.5714.541Menin (PF05053, IPR007747): Menin
135 MISPinteractor140.9120.479AKAP2_C (PF15304, IPR029304): A-kinase anchor protein 2 C-terminus
136 MPRIPinteractor190.6027.245Apolipoprotein (PF01442, IPR000074): Apolipoprotein A1/A4/E domain
Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus
Fez1 (PF06818): Fez1
FliT (PF05400, IPR008622): Flagellar protein FliT
HalX (PF08663, IPR013971): HalX domain
Mnd1 (PF03962, IPR005647): Mnd1 family
OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
IFT57 (PF10498, IPR019530): Intra-flagellar transport protein 57
YlqD (PF11068, IPR021297): YlqD protein
DUF3015 (PF11220, IPR021383): Protein of unknown function (DUF3015)
Noelin-1 (PF12308, IPR022082): Neurogenesis glycoprotein
TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding
Snapin_Pallidin (PF14712, IPR028119): Snapin/Pallidin
PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
137 MROH6interactor100HEAT (PF02985, IPR000357): HEAT repeat
HEAT_EZ (PF13513): HEAT-like repeat
138 MYConcoprotein320.196624.461HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain
Myc_N (PF01056, IPR012682): Myc amino-terminal region
139 MYH10interactor220.36832.048IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain
Myosin_tail_1 (PF01576, IPR002928): Myosin tail
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
140 MYH9suppressor1350.1872464.177IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain
Myosin_tail_1 (PF01576, IPR002928): Myosin tail
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
141 MYL1interactor30.6670.054Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
142 MYL10interactor21.0000EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
TC1 (PF15063, IPR020282): Thyroid cancer protein 1
143 MYL6interactor150.45718.652EF-hand_1 (PF00036, IPR002048, SM00054): EF hand
EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
144 MYL6Binteractor110.43613.409SapB_1 (PF05184, IPR007856): Saposin-like type B, region 1
EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
145 MYO18Ainteractor1010.2051012.239Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1
IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_tail_1 (PF01576, IPR002928): Myosin tail
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2
146 MYO19interactor1030.1901179.840IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
147 MYO1Binteractor250.51324.441IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_TH1 (PF06017, IPR010926): Unconventional myosin tail, actin- and lipid-binding
RNA_pol (PF00940, IPR002092): DNA-dependent RNA polymerase
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
AAA_23 (PF13476): AAA domain
148 MYO1Cinteractor690.277578.885IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_TH1 (PF06017, IPR010926): Unconventional myosin tail, actin- and lipid-binding
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
149 MYO1Einteractor200.63717.547IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_TH1 (PF06017, IPR010926): Unconventional myosin tail, actin- and lipid-binding
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
150 MYO5Ainteractor190.6736.292DIL (PF01843, IPR018444, SM01132): DIL domain
DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948)
HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
IncA (PF04156, IPR007285): IncA protein
IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Mod_r (PF07200, IPR009851): Modifier of rudimentary (Mod(r)) protein
Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
SOGA (PF11365, IPR027881): Protein SOGA
GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding
CYTL1 (PF15153, IPR029253): Cytokine-like protein 1
151 MYO5Binteractor120.8790.8085_3_exonuc (PF01367, IPR020045, SM00475): 5'-3' exonuclease, C-terminal SAM fold
bZIP_1 (PF00170, IPR004827): bZIP transcription factor
DIL (PF01843, IPR018444, SM01132): DIL domain
Fez1 (PF06818): Fez1
HalX (PF08663, IPR013971): HalX domain
IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain
Vir_act_alpha_C (PF10400, IPR018309): Virulence activator alpha C-term
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
DUF3251 (PF11622, IPR021658): Protein of unknown function (DUF3251)
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
152 MYO5Cinteractor550.356228.062DIL (PF01843, IPR018444, SM01132): DIL domain
DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664)
ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain
Pilus_CpaD (PF09476, IPR019027): Pilus biogenesis CpaD protein (pilus_cpaD)
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
YtxH (PF12732, IPR024623): YtxH-like protein
Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease
153 NAP1L5interactor21.0000NAP (PF00956, IPR002164): Nucleosome assembly protein (NAP)
SspB (PF04386, IPR007481): Stringent starvation protein B
Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP)
154 NCKIPSDoncoprotein30.6670.183DUF2013 (PF09431, IPR018556): Protein of unknown function (DUF2013)
Rcd1 (PF04078, IPR007216): Cell differentiation family, Rcd1-like
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
155 NDUFA9interactor70.4294.786Epimerase (PF01370, IPR001509): NAD dependent epimerase/dehydratase family
156 NEXNinteractor140.8244.601Cas_Csy4 (PF09618, IPR013396): CRISPR-associated protein (Cas_Csy4)
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2)
VIT (PF08487, IPR013694, SM00609): Vault protein inter-alpha-trypsin domain
DUF2951 (PF11166, IPR021337): Protein of unknown function (DUF2951)
Med2 (PF11214, IPR021017): Mediator complex subunit 2
DUF2897 (PF11446, IPR021550): Protein of unknown function (DUF2897)
DUF3824 (PF12868, IPR024436): Domain of unknwon function (DUF3824)
DUF4355 (PF14265, IPR025580): Domain of unknown function (DUF4355)
Casc1_N (PF15927, IPR031826): Cancer susceptibility candidate 1 N-terminus
Connexin40_C (PF16791, IPR031862): Connexin 40 C-terminal domain
157 NFATC2suppressor40.6670.286RHD_DNA_bind (PF00554, IPR011539): Rel homology DNA-binding domain
RHD_dimer (PF16179, IPR032397): Rel homology dimerisation domain
158 NPHP1interactor70.5332.095SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
FAM176 (PF14851): FAM176 family
Speriolin_N (PF15058, IPR029385): Speriolin N terminus
DUF4746 (PF15928, IPR031827): Domain of unknown function (DUF4746)
159 NRDCinteractor50.6670.474Cnd2 (PF05786, IPR022816): Condensin complex subunit 2
Peptidase_M16 (PF00675, IPR011765): Insulinase (Peptidase family M16)
Peptidase_M16_C (PF05193, IPR007863): Peptidase M16 inactive domain
Tom22 (PF04281, IPR005683): Mitochondrial import receptor subunit Tom22
Peptidase_M16_M (PF16187, IPR032632): Middle or third domain of peptidase_M16
160 NTRK1oncoprotein1030.1452450.730I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
161 NXF1interactor480.166459.895NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain
Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding
TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain
LRR_8 (PF13855, IPR001611): Leucine rich repeat
162 OBSL1interactor570.246369.851BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain
Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
163 OFD1protein found in more fusions100.5564.711APG6 (PF04111, IPR007243): Autophagy protein Apg6
Exonuc_VII_L (PF02601, IPR020579): Exonuclease VII, large subunit
GrpE (PF01025, IPR000740): GrpE
NPV_P10 (PF05531, IPR008702): Nucleopolyhedrovirus P10 protein
XhlA (PF10779, IPR019715): Haemolysin XhlA
DUF3372 (PF11852, IPR024561): Domain of unknown function (DUF3372)
LisH_2 (PF16045, IPR006594): LisH
164 OXR1interactor21.0000GRAM (PF02893, IPR004182, SM00568): GRAM domain
LysM (PF01476, IPR018392, SM00257): LysM domain
TLD (PF07534, IPR006571, SM00584): TLD
DUF3350 (PF11830, IPR021785): Domain of unknown function (DUF3350)
165 PACSIN3interactor110.6223.920FCH (PF00611, IPR001060, SM00055): Fes/CIP4, and EFC/F-BAR homology domain
GrpE (PF01025, IPR000740): GrpE
SH3_9 (PF14604, IPR001452): Variant SH3 domain
166 PARVAoncoprotein40.6670.733CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
167 PDLIM7interactor550.254298.278LIM (PF00412, IPR001781, SM00132): LIM domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
zinc_ribbon_10 (PF10058, IPR019273): Predicted integral membrane zinc-ribbon metal-binding protein
DUF4749 (PF15936, IPR031847): Domain of unknown function (DUF4749)
168 PEX14protein found in more fusions50.5001.889HemX (PF04375, IPR007470): HemX, putative uroporphyrinogen-III C-methyltransferase
Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region
CPSF100_C (PF13299, IPR025069): Cleavage and polyadenylation factor 2 C-terminal
PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated
TolA_bind_tri (PF16331, IPR032519): TolA binding protein trimerisation
169 PIK3C2Ainteractor180.74510.354C2 (PF00168, IPR000008, SM00239): C2 domain
PI3K_C2 (PF00792, IPR002420, SM00142): Phosphoinositide 3-kinase C2
PI3K_rbd (PF00794, IPR000341, SM00144): PI3-kinase family, ras-binding domain
PI3Ka (PF00613, IPR001263, SM00145): Phosphoinositide 3-kinase family, accessory domain (PIK domain)
PX (PF00787, IPR001683, SM00312): PX domain
PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
170 PIK3R2oncoprotein170.55117.825RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
PI3K_P85_iSH2 (PF16454, IPR032498): Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain
171 PLEConcoprotein300.37578.994CDC37_N (PF03234, IPR013855, SM01071): Cdc37 N terminal kinase binding
CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
FUSC (PF04632, IPR006726): Fusaric acid resistance protein family
RNA_pol_Rbc25 (PF08292, IPR013238): RNA polymerase III subunit Rpc25
S10_plectin (PF03501, IPR005326): Plectin/S10 domain
Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein
DUF2229 (PF09989, IPR018709): CoA enzyme activase uncharacterised domain (DUF2229)
Plectin (PF00681, IPR001101, SM00250): Plectin repeat
YlqD (PF11068, IPR021297): YlqD protein
Alanine_zipper (PF11839, IPR021793): Alanine-zipper, major outer membrane lipoprotein
DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391)
DUF4140 (PF13600, IPR025554): N-terminal domain of unknown function (DUF4140)
172 PLEKHG3interactor110.8910.426PH (PF00169, IPR001849, SM00233): PH domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
PH_10 (PF15411): Pleckstrin homology domain
173 PPARGC1Ainteractor40.8330.500Pap_E4 (PF02711, IPR003861): E4 protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
RSRP (PF17069): Arginine/Serine-Rich protein 1
174 PPME1protein found in more fusions100.6112.982Abhydrolase_6 (PF12697, IPR000073): Alpha/beta hydrolase family
175 PPP1CAsuppressor390.394136.804Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
176 PPP1CBinteractor980.216994.900Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
177 PPP1CConcoprotein410.378138.563Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
178 PPP1R12Ainteractor230.57727.498DUF1510 (PF07423, IPR009988): Protein of unknown function (DUF1510)
Mucin (PF01456, IPR000458): Mucin-like glycoprotein
RNA_pol_3_Rpc31 (PF11705, IPR024661): DNA-directed RNA polymerase III subunit Rpc31
DUF3682 (PF12446, IPR022152): Protein of unknown function (DUF3682)
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
DUF4050 (PF13259, IPR025124): Protein of unknown function (DUF4050)
AAA_23 (PF13476): AAA domain
Ank_5 (PF13857): Ankyrin repeats (many copies)
GEMIN8 (PF15348): Gemini of Cajal bodies-associated protein 8
PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
179 PPP1R12Binteractor61.0000Mem_trans (PF03547, IPR004776): Membrane transport protein
SAE2 (PF08573, IPR013882): DNA repair protein endonuclease SAE2/CtIP C-terminus
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
180 PPP1R18interactor140.7255.407Totivirus_coat (PF05518, IPR008871): Totivirus coat protein
DUF4124 (PF13511, IPR025392): Domain of unknown function (DUF4124)
Phostensin (PF13914, IPR025907): Phostensin PP1-binding and SH3-binding region
Phostensin_N (PF13916, IPR025903): PP1-regulatory protein, Phostensin N-terminal
181 PPP1R9Bprotein found in more fusions150.60015.082PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
Stm1_N (PF09598, IPR019084): Stm1
TSC22 (PF01166, IPR000580): TSC-22/dip/bun family
DUF2968 (PF11180, IPR021350): Protein of unknown function (DUF2968)
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
PRIMA1 (PF16101): Proline-rich membrane anchor 1
NuDC (PF16273, IPR032572): Nuclear distribution C domain
182 PPP2R2Csuppressor21.0000WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
183 PRKACAinteractor110.34516.941Pkinase (PF00069, IPR000719): Protein kinase domain
184 PRPSAP2interactor50.6003.104Pribosyltran_N (PF13793, IPR029099): N-terminal domain of ribose phosphate pyrophosphokinase
Pribosyl_synth (PF14572, IPR005946): Phosphoribosyl synthetase-associated domain
185 PSMA1interactor140.32128.429Proteasome (PF00227, IPR001353): Proteasome subunit
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
186 PTBP1oncoprotein270.40945.683RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
187 PTGR2oncoprotein21.0000ADH_zinc_N (PF00107, IPR013149): Zinc-binding dehydrogenase
ADH_zinc_N_2 (PF13602): Zinc-binding dehydrogenase
ADH_N_2 (PF16884): N-terminal domain of oxidoreductase
188 PTK2protein found in more fusions160.42921.852FERM_M (PF00373, IPR019748): FERM central domain
Focal_AT (PF03623, IPR005189): Focal adhesion targeting region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
UCMA (PF17085, IPR031386): Unique cartilage matrix associated protein
189 PXNoncoprotein110.47310.742LIM (PF00412, IPR001781, SM00132): LIM domain
Paxillin (PF03535): Paxillin family
190 QARSinteractor240.42456.694tRNA-synt_1c (PF00749, IPR020058): tRNA synthetases class I (E and Q), catalytic domain
tRNA-synt_1c_C (PF03950, IPR020059): tRNA synthetases class I (E and Q), anti-codon binding domain
tRNA_synt_1c_R1 (PF04558, IPR007639): Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1
tRNA_synt_1c_R2 (PF04557, IPR007638): Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2
191 RAC1oncoprotein170.45828.021Ras (PF00071, IPR001806, SM00173): Ras family
192 RAI14interactor220.57115.358Ank (PF00023, IPR002110, SM00248): Ankyrin repeat
Fez1 (PF06818): Fez1
FliJ (PF02050, IPR012823): Flagellar FliJ protein
Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region
DUF2408 (PF10303, IPR018810): Protein of unknown function (DUF2408)
TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
MscS_porin (PF12795, IPR024393): Mechanosensitive ion channel porin domain
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
AAA_13 (PF13166, IPR026866): AAA domain
Ank_5 (PF13857): Ankyrin repeats (many copies)
PKcGMP_CC (PF16808, IPR031831): Coiled-coil N-terminus of cGMP-dependent protein kinase
193 RAP1Asuppressor50.6002.154Ras (PF00071, IPR001806, SM00173): Ras family
194 RCC2oncoprotein120.4556.398RCC1 (PF00415, IPR000408): Regulator of chromosome condensation (RCC1) repeat
RCC1_2 (PF13540): Regulator of chromosome condensation (RCC1) repeat
195 RNF2interactor350.187199.826zf-C4_Topoisom (PF01396, IPR013498): Topoisomerase DNA binding C4 zinc finger
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
196 RPA1suppressor540.322232.002Rep-A_N (PF04057, IPR007199): Replication factor-A protein 1, N-terminal domain
Rep_fac-A_C (PF08646, IPR013955): Replication factor-A C terminal domain
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
REPA_OB_2 (PF16900, IPR031657): Replication protein A OB domain
197 RPA2oncoprotein440.290187.159RPA_C (PF08784, IPR014892): Replication protein A C terminal
tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
RMI2 (PF16100, IPR032245): RecQ-mediated genome instability protein 2
198 RPA3interactor410.304121.614Rep_fac-A_3 (PF08661, IPR013970): Replication factor A protein 3
199 RPLP0interactor280.32587.788Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
Ribosomal_L10 (PF00466, IPR001790): Ribosomal protein L10
200 RPS6KB2interactor170.36029.752Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
201 RPS6KC1interactor100MIT (PF04212, IPR007330, SM00745): MIT (microtubule interacting and transport) domain
Pkinase (PF00069, IPR000719): Protein kinase domain
PX (PF00787, IPR001683, SM00312): PX domain
202 RPTORprotein found in more fusions80.4294.075HEAT (PF02985, IPR000357): HEAT repeat
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
HEAT_2 (PF13646): HEAT repeats
Raptor_N (PF14538, IPR029347): Raptor N-terminal CASPase like domain
203 RUVBL1oncoprotein240.32467.195TIP49 (PF06068, IPR010339): TIP49 C-terminus
204 S100Boncoprotein40.6670.287S_100 (PF01023, IPR013787): S-100/ICaBP type calcium binding domain
205 SDHBsuppressor50.5002.289Fer2_3 (PF13085, IPR025192): 2Fe-2S iron-sulfur cluster binding domain
Fer4_8 (PF13183, IPR017896): 4Fe-4S dicluster domain
Fer4_17 (PF13534): 4Fe-4S dicluster domain
206 SEC16Ainteractor280.51644.428APC_r (PF05923): APC repeat
Sec16_C (PF12931, IPR024298): Sec23-binding domain of Sec16
Sec16 (PF12932, IPR024340): Vesicle coat trafficking protein Sec16 mid-region
207 SHC1oncoprotein340.337104.279PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID)
SH2 (PF00017, IPR000980, SM00252): SH2 domain
208 SIPA1oncoprotein90.8610.367IncA (PF04156, IPR007285): IncA protein
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
Rap_GAP (PF02145, IPR000331): Rap/ran-GAP
209 SIPA1L1interactor40.8330.286PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
Rap_GAP (PF02145, IPR000331): Rap/ran-GAP
SPAR_C (PF11881, IPR021818): C-terminal domain of SPAR protein
DUF4164 (PF13747, IPR025310): Domain of unknown function (DUF4164)
IQCJ-SCHIP1 (PF15157, IPR029362): Fusion protein IQCJ-SCHIP1 with IQ-like motif
210 SIPA1L3interactor90.8330.775IncA (PF04156, IPR007285): IncA protein
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
Rap_GAP (PF02145, IPR000331): Rap/ran-GAP
SPAR_C (PF11881, IPR021818): C-terminal domain of SPAR protein
211 SIRT7interactor470.212331.979DUF563 (PF04577, IPR007657): Protein of unknown function (DUF563)
SIR2 (PF02146, IPR003000): Sir2 family
212 SMC3oncoprotein150.39014.339SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
213 SNW1protein found in more fusions400.310239.265SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
SIR4_SID (PF16991, IPR031556): Sir4 SID domain
214 SORBS2oncoprotein140.8082.461Sorb (PF02208, IPR003127, SM00459): Sorbin homologous domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
215 SPECC1oncoprotein160.7254.439CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
Fez1 (PF06818): Fez1
Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region
KxDL (PF10241, IPR019371): Uncharacterized conserved protein
TSNAXIP1_N (PF15739, IPR032755): Translin-associated factor X-interacting N-terminus
PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
HMMR_N (PF15905, IPR031787): Hyaluronan mediated motility receptor N-terminal
SHE3 (PF17078, IPR031398): SWI5-dependent HO expression protein 3
216 SPECC1Linteractor150.6197.314CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
Prefoldin_2 (PF01920, IPR002777): Prefoldin subunit
TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
KASH_CCD (PF14662, IPR028168): Coiled-coil region of CCDC155 or KASH
Lebercilin (PF15619, IPR028933): Ciliary protein causing Leber congenital amaurosis disease
DUF4763 (PF15960, IPR031883): Domain of unknown function (DUF4763)
217 SPTAN1oncoprotein390.391145.075EFhand_Ca_insen (PF08726, IPR014837): Ca2+ insensitive EF hand
Spectrin (PF00435, IPR002017): Spectrin repeat
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
Tetrabrachion (PF11401, IPR021535): Tetrabrachion
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
E2F_CC-MB (PF16421, IPR032198): E2F transcription factor CC-MB domain
218 SPTBN1suppressor350.44970.958CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
COG2 (PF06148, IPR024602): COG (conserved oligomeric Golgi) complex component, COG2
DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764)
Spectrin (PF00435, IPR002017): Spectrin repeat
PH_9 (PF15410): Pleckstrin homology domain
219 SPTBN2interactor150.6953.601BEX (PF04538, IPR021156): Brain expressed X-linked like family
CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
Spectrin (PF00435, IPR002017): Spectrin repeat
Mating_N (PF12731, IPR024333): Mating-type protein beta 1
DUF4110 (PF13422, IPR025183): Domain of unknown function (DUF4110)
PH_9 (PF15410): Pleckstrin homology domain
220 SRConcoprotein240.249689.353Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
221 SSFA2interactor130.6284.847KRAP_IP3R_bind (PF14722, IPR029325): Ki-ras-induced actin-interacting protein-IP3R-interacting domain
SSFA2_C (PF14723, IPR029326): Sperm-specific antigen 2 C-terminus
222 SSH2interactor110.9450.248DEK_C (PF08766, IPR014876): DEK C terminal domain
DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain
223 STAU1protein found in more fusions250.43835.661dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
Staufen_C (PF16482, IPR032478): Staufen C-terminal domain
224 SVILinteractor260.61819.647Gelsolin (PF00626, IPR007123): Gelsolin repeat
VHP (PF02209, IPR003128, SM00153): Villin headpiece domain
DUF4695 (PF15766, IPR031521): Domain of unknown function (DUF4695)
225 SYNCRIPinteractor240.39154.076RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Limkain-b1 (PF11608, IPR024582): Limkain b1
226 SYNPOinteractor1000.2131001.904Calsarcin (PF05556, IPR008438): Calcineurin-binding protein (Calsarcin)
227 TESsuppressor80.8570.461LIM (PF00412, IPR001781, SM00132): LIM domain
PET (PF06297, IPR010442): PET Domain
PSCyt3 (PF07627, IPR013039): Protein of unknown function (DUF1588)
Ig_Tie2_1 (PF10430, IPR018941): Tie-2 Ig-like domain 1
228 TGFBR2suppressor60.5333.113ecTbetaR2 (PF08917, IPR015013): Transforming growth factor beta receptor 2 ectodomain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
229 TJP2oncoprotein100.44410.577PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
SH3_2 (PF07653, IPR011511): Variant SH3 domain
Guanylate_kin (PF00625, IPR008145, SM00072): Guanylate kinase
230 TMOD1interactor210.66219.051Tropomodulin (PF03250, IPR004934): Tropomodulin
231 TMOD3interactor230.54524.438Tropomodulin (PF03250, IPR004934): Tropomodulin
Usher (PF00577, IPR000015): Outer membrane usher protein
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
232 TP53suppressor590.236824.754DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
P53 (PF00870, IPR011615): P53 DNA-binding domain
P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
233 TPM1protein found in more fusions210.7008.234Tropomyosin (PF00261, IPR000533): Tropomyosin
Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like
234 TPM2protein found in more fusions270.49544.981DASH_Spc19 (PF08287, IPR013251): Spc19
Tropomyosin (PF00261, IPR000533): Tropomyosin
Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like
235 TPM3oncoprotein290.42950.499Tropomyosin (PF00261, IPR000533): Tropomyosin
Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like
236 TPM4oncoprotein230.59323.294Tropomyosin (PF00261, IPR000533): Tropomyosin
Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like
237 TPRNinteractor150.8860.913DUF2052 (PF09747, IPR018613): Coiled-coil domain containing protein (DUF2052)
Phostensin (PF13914, IPR025907): Phostensin PP1-binding and SH3-binding region
Phostensin_N (PF13916, IPR025903): PP1-regulatory protein, Phostensin N-terminal
238 TRAP1oncoprotein140.47310.825HSP90 (PF00183, IPR001404): Hsp90 protein
HATPase_c_3 (PF13589): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
239 TRIOBPinteractor80.7861.542FadA (PF09403, IPR018543): Adhesion protein FadA
OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
PH (PF00169, IPR001849, SM00233): PH domain
bZIP_2 (PF07716, IPR004827, SM00338): Basic region leucine zipper
TMF_DNA_bd (PF12329, IPR022092): TATA element modulatory factor 1 DNA binding
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
240 TSG101suppressor120.4558.483APG6 (PF04111, IPR007243): Autophagy protein Apg6
Laminin_II (PF06009, IPR010307): Laminin Domain II
UEV (PF05743, IPR008883): UEV domain
Vps23_core (PF09454, IPR017916): Vps23 core domain
241 TUBGCP3interactor120.6217.321Spc97_Spc98 (PF04130, IPR007259): Spc97 / Spc98 family
242 TWF1interactor190.49733.238Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein
243 U2AF2protein found in more fusions310.35985.034RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Transformer (PF06495, IPR010519): Fruit fly transformer protein
244 UBASH3Binteractor170.5839.532His_Phos_1 (PF00300, IPR013078, SM00855): Histidine phosphatase superfamily (branch 1)
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
2_5_RNA_ligase2 (PF13563): 2'-5' RNA ligase superfamily
SH3_9 (PF14604, IPR001452): Variant SH3 domain
245 UBE2Iinteractor170.333157.728UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
246 UQCRQinteractor30.6670.182UcrQ (PF02939, IPR004205): UcrQ family
247 USP46interactor40.5000.904UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
248 USP7oncoprotein180.38228.132MATH (PF00917, IPR002083, SM00061): MATH domain
UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
USP7_ICP0_bdg (PF12436, IPR024729): ICP0-binding domain of Ubiquitin-specific protease 7
USP7_C2 (PF14533, IPR029346): Ubiquitin-specific protease C-terminal
249 VCAM1interactor390.275144.059C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
250 VCPprotein found in more fusions470.278291.500AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2
CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain
TniB (PF05621, IPR008868): Bacterial TniB protein
Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain
DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944)
251 WASLinteractor130.42316.983Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
PBD (PF00786, IPR000095, SM00285): P21-Rho-binding domain
WH1 (PF00568, IPR000697, SM00461): WH1 domain
WH2 (PF02205, IPR003124, SM00246): WH2 motif
RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein
Caskin-Pro-rich (PF16907): Proline rich region of Caskin proteins
252 WDR1interactor240.48941.826eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A
PQQ (PF01011, IPR002372, SM00564): PQQ enzyme repeat
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
253 WDR3interactor70.5710.972YbaB_DNA_bd (PF02575, IPR004401): YbaB/EbfC DNA-binding family
Nucleoporin_N (PF08801, IPR014908): Nup133 N terminal like
Utp12 (PF04003, IPR007148): Dip2/Utp12 Family
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
WD40_like (PF17005, IPR031544): WD40-like domain
254 WHSC1oncoprotein70.4674.677PHD (PF00628, IPR019787, SM00249): PHD-finger
PWWP (PF00855, IPR000313, SM00293): PWWP domain
REV (PF00424, IPR000625): REV protein (anti-repression trans-activator protein)
SET (PF00856, IPR001214, SM00317): SET domain
HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
zf-HC5HC2H (PF13771): PHD-like zinc-binding domain
zf-HC5HC2H_2 (PF13832): PHD-zinc-finger like domain
255 YWHAQinteractor370.306191.10114-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
256 ZBTB20interactor61.0000BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
GTPase_binding (PF09027, IPR015116): GTPase binding
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
257 ZDHHC5interactor51.00007TMR-DISM_7TM (PF07695, IPR011623): 7TM diverse intracellular signalling
zf-DHHC (PF01529, IPR001594): DHHC palmitoyltransferase

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