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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)217
The number (and %) of the onco-proteins71 (32.72 %)
The number (and %) of the tumor suppressors29 (13.36 %)
Total number of binary PPIs (saturation %)2120 (9.05 %)
The number (and %) of affected PPIs215 (10.14 %)
The number of possible different fusions47
PPI diameter5
PPI radius3
The average degree of PPI18.645
Assortativity coefficient-0.2097
The network average Clustering coefficient0.470
The number (and %) of a zero Clustering coefficients10 (4.61 %)
The number (and %) of a zero Betweenness Centrality28 (12.90 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: ACE,HSPD1 All fusions
Proteins found in more fusions HMG20A (see 2 fusions); U2AF2 (see 2 fusions); CUL1 (see 3 fusions); GRB2 (see 1 fusions); LGALS3BP (see 2 fusions); EWSR1 (see 2 fusions); GAN (see 1 fusions); NAGK (see 1 fusions); FTL (see 3 fusions); HDAC5 (see 1 fusions); PLOD3 (see 2 fusions); PACSIN2 (see 1 fusions); SNW1 (see 1 fusions); APP (see 4 fusions); CUL4A (see 4 fusions); VCP (see 4 fusions); HUWE1 (see 2 fusions); HSP90AB1 (see 1 fusions); STUB1 (see 1 fusions); CSNK2A1 (see 1 fusions); DDX17 (see 3 fusions); GAPDH (see 3 fusions); TUBG1 (see 1 fusions); STAU1 (see 2 fusions); CEP70 (see 1 fusions); CUL7 (see 2 fusions); CUL3 (see 1 fusions); MYC (see 1 fusions); HSPD1/HSPA8 (see 1 fusions); CDH1 (see 3 fusions); ACTB (see 3 fusions); TMCC2 (see 3 fusions); SKI (see 1 fusions); COPS5 (see 1 fusions); UBC (see 1 fusions); LRRK2 (see 1 fusions); CLU (see 5 fusions); BCR/ABL1 (see 183 fusions); LMNA (see 3 fusions); CRY2 (see 3 fusions); PUF60 (see 2 fusions); NR3C1 (see 8 fusions); MAPK14 (see 1 fusions); BCOR (see 1 fusions); MCM2 (see 1 fusions); CDK9 (see 2 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 ACEparental protein70.143452.431Peptidase_M2 (PF01401, IPR001548): Angiotensin-converting enzyme
2 HSPD1parental protein2080.07625933.703Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
3 ABL1oncoprotein150.52714.737Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
F_actin_bind (PF08919, IPR015015, SM00808): F-actin binding
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
FRG2 (PF15315, IPR026245): Facioscapulohumeral muscular dystrophy candidate 2
4 ACTBoncoprotein430.213447.818Actin (PF00022, IPR004000, SM00268): Actin
5 ADRB2interactor210.33749.7857tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
6 AGTinteractor30.3334.246Nuc_rec_co-act (PF08815, IPR014920): Nuclear receptor coactivator
Serpin (PF00079, IPR023796, SM00093): Serpin (serine protease inhibitor)
7 AHSA1interactor230.41567.652Aha1_N (PF09229, IPR015310, SM01000): Activator of Hsp90 ATPase, N-terminal
AHSA1 (PF08327, IPR013538): Activator of Hsp90 ATPase homolog 1-like protein
8 ALDH2oncoprotein60.5331.704Aldedh (PF00171, IPR015590): Aldehyde dehydrogenase family
DUF1235 (PF06822, IPR009641): Protein of unknown function (DUF1235)
9 ALDOAinteractor260.38070.006Glycolytic (PF00274, IPR000741): Fructose-bisphosphate aldolase class-I
10 ALKoncoprotein50.6005.214MAM (PF00629, IPR000998, SM00137): MAM domain, meprin/A5/mu
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Ldl_recept_a (PF00057, IPR002172, SM00192): Low-density lipoprotein receptor domain class A
Gly_rich (PF12810): Glycine rich protein
FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site
11 AMBRA1interactor120.6213.533Acyl_CoA_thio (PF02551, IPR025652): Acyl-CoA thioesterase
eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Spt20 (PF12090, IPR021950): Spt20 family
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
12 AMFRoncoprotein130.54518.592CUE (PF02845, IPR003892, SM00546): CUE domain
UbiA (PF01040, IPR000537): UbiA prenyltransferase family
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
13 APPprotein found in more fusions480.164617.850APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding
Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP)
BUD22 (PF09073, IPR015158): BUD22
IncA (PF04156, IPR007285): IncA protein
Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus
APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
14 ASB4interactor40.5000.473Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_4 (PF13637): Ankyrin repeats (many copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
SOCS_box (PF07525, IPR001496): SOCS box
15 ASB9interactor40.3339.363Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
SOCS_box (PF07525, IPR001496): SOCS box
16 ATF2oncoprotein170.25036.265bZIP_1 (PF00170, IPR004827): bZIP transcription factor
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
17 ATP5F1interactor70.6671.806Mt_ATP-synt_B (PF05405, IPR008688): Mitochondrial ATP synthase B chain precursor (ATP-synt_B)
DUF2105 (PF09878, IPR019212): Predicted membrane protein (DUF2105)
18 ATP6V1Ainteractor60.5330.800ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain
ATP-synt_ab_N (PF02874, IPR004100): ATP synthase alpha/beta family, beta-barrel domain
ATP-synt_ab_Xtn (PF16886, IPR031686): ATPsynthase alpha/beta subunit N-term extension
19 AURKAoncoprotein230.45548.572Pkinase (PF00069, IPR000719): Protein kinase domain
MTBP_C (PF14920, IPR029418): MDM2-binding
20 AURKBinteractor220.51421.442Pkinase (PF00069, IPR000719): Protein kinase domain
21 BAK1oncoprotein50.5002.333Bcl-2 (PF00452, IPR026298): Apoptosis regulator proteins, Bcl-2 family
22 BAXsuppressor80.3819.177Bcl-2 (PF00452, IPR026298): Apoptosis regulator proteins, Bcl-2 family
23 BCORoncoprotein80.5714.866Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
BCOR (PF15808, IPR031628): BCL-6 co-repressor, non-ankyrin-repeat region
PUFD (PF16553, IPR032365): BCORL-PCGF1-binding domain
24 BCRoncoprotein100.6893.982Bcr-Abl_Oligo (PF09036, IPR015123): Bcr-Abl oncoprotein oligomerisation domain
C2 (PF00168, IPR000008, SM00239): C2 domain
PH (PF00169, IPR001849, SM00233): PH domain
RhoGAP (PF00620, IPR000198, SM00324): RhoGAP domain
RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain
IQ_SEC7_PH (PF16453, IPR001849): PH domain
25 BDKRB2interactor1007tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
26 BRCA1suppressor220.35252.303BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT
27 C11orf58interactor60.46717.890DUF3408 (PF11888, IPR021823): Protein of unknown function (DUF3408)
SMAP (PF15477, IPR028124): Small acidic protein family
28 C12orf10interactor80.4646.808UPF0160 (PF03690, IPR003226): Uncharacterised protein family (UPF0160)
29 C1QBPinteractor310.310119.518MAM33 (PF02330, IPR003428): Mitochondrial glycoprotein
DUF3053 (PF11254, IPR021413): Protein of unknown function (DUF3053)
30 CA2interactor60.6672.547Carb_anhydrase (PF00194, IPR001148, SM01057): Eukaryotic-type carbonic anhydrase
31 CAND1interactor490.427163.541Adaptin_N (PF01602, IPR002553): Adaptin N terminal region
DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981)
HEAT (PF02985, IPR000357): HEAT repeat
TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20)
RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1
DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385)
MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II
32 CASP3interactor80.3816.297Peptidase_C14 (PF00656, IPR011600): Caspase domain
33 CCAR2suppressor200.28453.130DREPP (PF05558, IPR008469): DREPP plasma membrane polypeptide
IncA (PF04156, IPR007285): IncA protein
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
DBC1 (PF14443, IPR025954, SM01122): DBC1
S1-like (PF14444, IPR025223): S1-like
34 CCDC8interactor320.370102.101Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
PNMA (PF14893, IPR026523): PNMA
35 CD4suppressor140.46212.126ATP1G1_PLM_MAT8 (PF02038, IPR000272): ATP1G1/PLM/MAT8 family
C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain
CD4-extracel (PF09191, IPR015274): CD4, extracellular
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
Tcell_CD4_C (PF12104, IPR021963): T cell CD4 receptor C terminal region
36 CDC20oncoprotein220.48130.258WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
37 CDC5Linteractor440.417148.092OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat
Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component
Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain
38 CDH1suppressor130.25830.404Cadherin_C (PF01049, IPR000233): Cadherin cytoplasmic region
Cadherin_pro (PF08758, IPR014868, SM01055): Cadherin prodomain like
Cadherin (PF00028, IPR002126, SM00112): Cadherin domain
39 CDK2suppressor410.377157.434Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family
Pkinase (PF00069, IPR000719): Protein kinase domain
40 CDK9protein found in more fusions190.45829.354Pkinase (PF00069, IPR000719): Protein kinase domain
41 CDKN2AIPinteractor90.6942.336XTBD (PF11952, IPR021859): XRN-Two Binding Domain, XTBD
42 CEP170P1interactor40.6670.400NA
43 CEP70protein found in more fusions40.6670.400IncA (PF04156, IPR007285): IncA protein
Mog1 (PF04603, IPR007681): Ran-interacting Mog1 protein
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region
Colicin-DNase (PF12639, IPR024622): DNase/tRNase domain of colicin-like bacteriocin
44 CFTRsuppressor150.49514.999ABC_membrane (PF00664, IPR001140): ABC transporter transmembrane region
ABC_tran (PF00005, IPR003439): ABC transporter
Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase
SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
Rotamase_2 (PF13145, IPR000297): PPIC-type PPIASE domain
CFTR_R (PF14396, IPR025837): Cystic fibrosis TM conductance regulator (CFTR), regulator domain
45 CLEC7Ainteractor200Chordopox_A33R (PF05966, IPR009238): Chordopoxvirus A33R protein
Ly49 (PF08391, IPR013600): Ly49-like protein, N-terminal region
Lectin_C (PF00059, IPR001304, SM00034): Lectin C-type domain
46 CLUsuppressor110.5118.512Clusterin (PF01093, IPR000753): Clusterin
47 COLGALT1interactor50.6001.259Glyco_transf_25 (PF01755, IPR002654): Glycosyltransferase family 25 (LPS biosynthesis protein)
Glyco_tranf_2_4 (PF13704): Glycosyl transferase family 2
48 COPS5protein found in more fusions520.348312.200JAB (PF01398, IPR000555, SM00232): JAB1/Mov34/MPN/PAD-1 ubiquitin protease
49 CRY2protein found in more fusions130.6063.618DNA_photolyase (PF00875, IPR006050): DNA photolyase
FAD_binding_7 (PF03441, IPR005101): FAD binding domain of DNA photolyase
50 CSNK2A1oncoprotein330.228327.583Pkinase (PF00069, IPR000719): Protein kinase domain
51 CUL1suppressor500.412212.352Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
52 CUL2suppressor360.43797.197Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
53 CUL3protein found in more fusions620.311474.805Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
54 CUL4Aprotein found in more fusions320.434111.679Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
55 CUL7protein found in more fusions430.305208.936ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10)
Cullin (PF00888, IPR001373, SM00182): Cullin family
DUF1918 (PF08940, IPR015035): Domain of unknown function (DUF1918)
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
Cul7 (PF11515, IPR021097): Mouse development and cellular proliferation protein Cullin-7
56 CXorf56interactor40.5003.032DUF4410 (PF14366, IPR025522): Domain of unknown function (DUF4410)
57 DCAF5interactor31.0000WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
DUF2634 (PF10934, IPR020288): Protein of unknown function (DUF2634)
IMUP (PF15761, IPR026621): Immortalisation up-regulated protein
58 DCLRE1Binteractor100DRMBL (PF07522, IPR011084): DNA repair metallo-beta-lactamase
Lactamase_B_2 (PF12706, IPR001279): Beta-lactamase superfamily domain
59 DDB2suppressor70.5331.901WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
60 DDX17protein found in more fusions430.341153.762CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Ferritin (PF00210, IPR008331): Ferritin-like domain
GRP (PF07172, IPR010800): Glycine rich protein family
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
61 DDX39Binteractor190.28141.051DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
62 DHFRinteractor31.0000DHFR_1 (PF00186, IPR001796): Dihydrofolate reductase
63 EEDsuppressor300.335115.827WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
64 EEF1B2interactor270.33265.196EF1_GNE (PF00736, IPR014038, SM00888): EF-1 guanine nucleotide exchange domain
EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region
GST_C_6 (PF17171): Glutathione S-transferase, C-terminal domain
65 EEF2interactor340.333130.249EFG_C (PF00679, IPR000640, SM00838): Elongation factor G C-terminus
EFG_IV (PF03764, IPR005517, SM00889): Elongation factor G, domain IV
GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
EFG_II (PF14492, IPR009022): Elongation Factor G, domain II
66 EIF4Eoncoprotein70.5241.738IF4E (PF01652, IPR001040): Eukaryotic initiation factor 4E
67 EIF5Ainteractor140.47320.225EFP_N (PF08207, IPR013185): Elongation factor P (EF-P) KOW-like domain
eIF-5a (PF01287, IPR020189): Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold
68 ERGoncoprotein110.6005.260Ets (PF00178, IPR000418, SM00413): Ets-domain
SAM_2 (PF07647, IPR011510): SAM domain (Sterile alpha motif)
SAM_PNT (PF02198, IPR003118, SM00251): Sterile alpha motif (SAM)/Pointed domain
69 ESR1suppressor390.309206.008Oest_recep (PF02159, IPR001292): Oestrogen receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
ESR1_C (PF12743, IPR024736): Oestrogen-type nuclear receptor final C-terminal
70 ESRRBsuppressor110.6731.658zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
71 ETFBKMTinteractor31.0000PrmA (PF06325, IPR010456): Ribosomal protein L11 methyltransferase (PrmA)
72 EWSR1oncoprotein400.278518.771RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
Keratin_2_head (PF16208, IPR032444): Keratin type II head
73 FBXO17interactor31.0000FBA (PF04300, IPR007397): F-box associated region
F-box-like (PF12937, IPR001810): F-box-like
74 FBXO6interactor330.309139.074FBA (PF04300, IPR007397): F-box associated region
F-box-like (PF12937, IPR001810): F-box-like
75 FBXO7interactor70.6671.688Elongin_A (PF06881, IPR010684): RNA polymerase II transcription factor SIII (Elongin) subunit A
PI31_Prot_N (PF11566, IPR021625): PI31 proteasome regulator N-terminal
F-box-like (PF12937, IPR001810): F-box-like
76 FN1oncoprotein400.290225.205fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain
fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
77 FTLprotein found in more fusions50.5001.524Ferritin (PF00210, IPR008331): Ferritin-like domain
78 FUSsuppressor470.427173.281Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
Limkain-b1 (PF11608, IPR024582): Limkain b1
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
Keratin_2_head (PF16208, IPR032444): Keratin type II head
79 GANprotein found in more fusions110.6671.096BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
Kelch_1 (PF01344, IPR006652, SM00612): Kelch motif
Kelch_3 (PF13415): Galactose oxidase, central domain
Kelch_5 (PF13854): Kelch motif
80 GAPDHoncoprotein440.354213.959Gp_dh_C (PF02800, IPR020829): Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
Gp_dh_N (PF00044, IPR020828, SM00846): Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain
OstA (PF03968, IPR005653): OstA-like protein
81 GBAinteractor50.6000.410Glyco_hydro_30 (PF02055, IPR001139): Glycosyl hydrolase family 30 TIM-barrel domain
Glyco_hydro_30C (PF17189): Glycosyl hydrolase family 30 beta sandwich domain
82 GBASinteractor80.6432.255NIPSNAP (PF07978, IPR012577): NIPSNAP
83 GDAinteractor60.6005.173Amidohydro_1 (PF01979, IPR006680): Amidohydrolase family
84 GID8interactor40.6670.286LisH (PF08513, IPR013720, SM00667): LisH
CLTH (PF10607, IPR024964): CTLH/CRA C-terminal to LisH motif domain
85 GLOD4interactor40.6671.747Glyoxalase (PF00903, IPR004360): Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
86 GMPPBinteractor40.3337.280Hexapep (PF00132, IPR001451): Bacterial transferase hexapeptide (six repeats)
NTP_transferase (PF00483, IPR005835): Nucleotidyl transferase
87 GRB2oncoprotein330.377380.458SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
DUF5093 (PF17011, IPR031533): Domain of unknown function (DUF5093)
88 GSRinteractor80.6672.126Pyr_redox_2 (PF07992, IPR023753): Pyridine nucleotide-disulphide oxidoreductase
Pyr_redox_dim (PF02852, IPR004099): Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
89 HDAC1suppressor210.24796.786FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide
Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
90 HDAC5protein found in more fusions270.40344.176Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
NOA36 (PF06524, IPR010531): NOA36 protein
Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3
HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
91 HEXIM1oncoprotein70.3815.708APG6 (PF04111, IPR007243): Autophagy protein Apg6
DivIC (PF04977, IPR007060): Septum formation initiator
Shugoshin_N (PF07558, IPR011516): Shugoshin N-terminal coiled-coil region
HEXIM (PF15313, IPR024872): Hexamethylene bis-acetamide-inducible protein
92 HIST1H3Einteractor100.40010.558Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
93 HIST2H2BEinteractor170.43414.950Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
94 HMG20Aprotein found in more fusions50.6671.067DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764)
DUF812 (PF05667, IPR008530): Protein of unknown function (DUF812)
MlaC (PF05494, IPR008869): MlaC protein
HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
95 HNRNPA1interactor740.303675.411RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
HnRNPA1 (PF11627, IPR021662): Nuclear factor hnRNPA1
96 HNRNPA2B1oncoprotein490.310200.894RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
97 HNRNPH1oncoprotein470.352159.209RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-RNPHF (PF08080, IPR012996): RNPHF zinc finger
98 HSP90AB1oncoprotein700.276597.276HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
HSP90 (PF00183, IPR001404): Hsp90 protein
99 HSPA1Ainteractor500.272284.587HSP70 (PF00012, IPR013126): Hsp70 protein
100 HSPA4interactor470.241418.921Herpes_ICP4_N (PF03584, IPR005206): Herpesvirus ICP4-like protein N-terminal region
HSP70 (PF00012, IPR013126): Hsp70 protein
TP53IP5 (PF15331, IPR029290): Cellular tumour antigen p53-inducible 5
101 HSPA5oncoprotein790.2501027.613HSP70 (PF00012, IPR013126): Hsp70 protein
102 HSPA8oncoprotein760.234950.237HSP70 (PF00012, IPR013126): Hsp70 protein
103 HSPA9oncoprotein570.231432.468HSP70 (PF00012, IPR013126): Hsp70 protein
104 HSPE1interactor210.28690.655Cpn10 (PF00166, IPR020818, SM00883): Chaperonin 10 Kd subunit
105 HUWE1oncoprotein420.285209.870BUD22 (PF09073, IPR015158): BUD22
DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908)
DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913)
FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation
HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family
Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm
Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM)
Mucin (PF01456, IPR000458): Mucin-like glycoprotein
Nop14 (PF04147, IPR007276): Nop14-like family
PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
WWE (PF02825, IPR004170, SM00678): WWE domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54
U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal
DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414)
106 ISG15suppressor200.28955.950ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
107 ITGA4interactor340.390104.215FG-GAP (PF01839, IPR013517): FG-GAP repeat
Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region
Integrin_alpha2 (PF08441, IPR013649): Integrin alpha
108 ITGB1suppressor110.4006.976EGF_2 (PF07974, IPR013111): EGF-like domain
Integrin_b_cyt (PF08725, IPR014836): Integrin beta cytoplasmic domain
Integrin_B_tail (PF07965, IPR012896): Integrin beta tail domain
Integrin_beta (PF00362, IPR002369, SM00187): Integrin beta chain VWA domain
PSI_integrin (PF17205): Integrin plexin domain
109 KRASoncoprotein130.37919.017Ras (PF00071, IPR001806, SM00173): Ras family
110 KRT31interactor60.3336.373Filament (PF00038, IPR001664): Intermediate filament protein
111 KRT40interactor31.0000Filament (PF00038, IPR001664): Intermediate filament protein
UPF0184 (PF03670, IPR022788): Uncharacterised protein family (UPF0184)
112 KRTAP10-3interactor60.60016.096Keratin_B2 (PF01500, IPR002494): Keratin, high sulfur B2 protein
Keratin_B2_2 (PF13885, IPR002494): Keratin, high sulfur B2 protein
113 KRTAP10-8interactor51.0000Keratin_B2 (PF01500, IPR002494): Keratin, high sulfur B2 protein
PMG (PF05287, IPR007951): PMG protein
Keratin_B2_2 (PF13885, IPR002494): Keratin, high sulfur B2 protein
114 KRTAP5-9interactor50.7003.082Ery_res_leader2 (PF08057, IPR012559): Erythromycin resistance leader peptide
115 LAMB1interactor50.6000.573Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus
CorA (PF01544, IPR002523): CorA-like Mg2+ transporter protein
DUF812 (PF05667, IPR008530): Protein of unknown function (DUF812)
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
YscO (PF07321, IPR009929): Type III secretion protein YscO
Laminin_EGF (PF00053, IPR002049, SM00180): Laminin EGF domain
Laminin_N (PF00055, IPR008211, SM00136): Laminin N-terminal (Domain VI)
Alanine_zipper (PF11839, IPR021793): Alanine-zipper, major outer membrane lipoprotein
Ntox1 (PF15500, IPR029137): Putative RNase-like toxin, toxin_1
116 LAMB3interactor50.5002.510ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948)
HR1 (PF02185, IPR011072, SM00742): Hr1 repeat
Laminin_II (PF06009, IPR010307): Laminin Domain II
Laminin_EGF (PF00053, IPR002049, SM00180): Laminin EGF domain
Laminin_N (PF00055, IPR008211, SM00136): Laminin N-terminal (Domain VI)
Alanine_zipper (PF11839, IPR021793): Alanine-zipper, major outer membrane lipoprotein
KELK (PF15796, IPR031597): KELK-motif containing domain of MRCK Ser/Thr protein kinase
SOAR (PF16533, IPR032393): STIM1 Orai1-activating region
117 LGALS3BPoncoprotein290.47961.278BACK (PF07707, IPR011705, SM00875): BTB And C-terminal Kelch
SRCR (PF00530, IPR001190): Scavenger receptor cysteine-rich domain
SRCR_2 (PF15494, IPR017448): Scavenger receptor cysteine-rich domain
118 LGR4interactor80.28613.6037tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
LRRNT (PF01462, IPR000372, SM00013): Leucine rich repeat N-terminal domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
119 LMNAprotein found in more fusions320.234301.856Filament (PF00038, IPR001664): Intermediate filament protein
LTD (PF00932, IPR001322): Lamin Tail Domain
Uso1_p115_C (PF04871, IPR006955): Uso1 / p115 like vesicle tethering protein, C terminal region
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
120 LRRC28interactor21.0000LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
121 LRRK2oncoprotein120.47317.297Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
ATP-synt_ab (PF00006, IPR000194): ATP synthase alpha/beta family, nucleotide-binding domain
DUF1043 (PF06295, IPR009386): Protein of unknown function (DUF1043)
T2SSE (PF00437, IPR001482): Type II/IV secretion system protein
Roc (PF08477, IPR013684): Ras of Complex, Roc, domain of DAPkinase
Pkinase (PF00069, IPR000719): Protein kinase domain
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
PQQ_2 (PF13360, IPR002372): PQQ-like domain
LRR_8 (PF13855, IPR001611): Leucine rich repeat
COR (PF16095, IPR032171): C-terminal of Roc, COR, domain
122 LZTS2suppressor50.6003.529CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
DUF1127 (PF06568, IPR009506): Domain of unknown function (DUF1127)
Fez1 (PF06818): Fez1
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
DUF4250 (PF14056, IPR025346): Domain of unknown function (DUF4250)
123 MAPK14oncoprotein140.29531.888Pkinase (PF00069, IPR000719): Protein kinase domain
124 MAPK6oncoprotein60.7002.364Pkinase (PF00069, IPR000719): Protein kinase domain
125 MCCC2interactor100.4725.292Carboxyl_trans (PF01039, IPR000022): Carboxyl transferase domain
126 MCM2oncoprotein540.340362.634AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA)
MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
127 METTL21Binteractor80.7861.259Methyltransf_16 (PF10294, IPR019410): Lysine methyltransferase
128 MOV10interactor360.211289.286AAA_12 (PF13087): AAA domain
AAA_30 (PF13604): AAA domain
129 MRPL37interactor90.6942.759PDCD9 (PF07147, IPR010793): Mitochondrial 28S ribosomal protein S30 (PDCD9)
130 MRPL4interactor90.47214.427Ribosomal_L4 (PF00573, IPR002136): Ribosomal protein L4/L1 family
131 MRPL58interactor140.33033.746RF-1 (PF00472, IPR000352): RF-1 domain
132 MYConcoprotein320.258144.393HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain
Myc_N (PF01056, IPR012682): Myc amino-terminal region
133 MYH9suppressor280.315208.193IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
Myosin_N (PF02736, IPR004009): Myosin N-terminal SH3-like domain
Myosin_tail_1 (PF01576, IPR002928): Myosin tail
Myosin_head (PF00063, IPR001609, SM00242): Myosin head (motor domain)
134 NAGKprotein found in more fusions51.0000BcrAD_BadFG (PF01869, IPR002731): BadF/BadG/BcrA/BcrD ATPase family
135 NCAPD2oncoprotein110.30921.741Adaptin_N (PF01602, IPR002553): Adaptin N terminal region
RMI1_N (PF08585, IPR013894, SM01161): RecQ mediated genome instability protein
HEAT (PF02985, IPR000357): HEAT repeat
LrgA (PF03788, IPR005538): LrgA family
Proteasom_PSMB (PF10508, IPR019538): Proteasome non-ATPase 26S subunit
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
Cnd3 (PF12719, IPR025977): Nuclear condensing complex subunits, C-term domain
Cnd1_N (PF12922, IPR024324): non-SMC mitotic condensation complex subunit 1, N-term
136 NEDD8interactor280.58722.071ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
137 NIPSNAP1interactor110.4189.158NIPSNAP (PF07978, IPR012577): NIPSNAP
138 NOS1APinteractor21.0000Phage_GPO (PF05929, IPR009228): Phage capsid scaffolding protein (GPO) serine peptidase
PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID)
139 NOS2interactor130.6213.359FAD_binding_1 (PF00667, IPR003097): FAD binding domain
Flavodoxin_1 (PF00258, IPR008254): Flavodoxin
NAD_binding_1 (PF00175, IPR001433): Oxidoreductase NAD-binding domain
NO_synthase (PF02898, IPR004030): Nitric oxide synthase, oxygenase domain
140 NOTCH2NLinteractor60.5335.578EGF (PF00008, IPR000742, SM00181): EGF-like domain
EGF_alliinase (PF04863, IPR006947): Alliinase EGF-like domain
EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
141 NR3C1protein found in more fusions100.4449.943GCR (PF02155, IPR001409): Glucocorticoid receptor
zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
142 NTRK1oncoprotein790.2081419.078I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
143 NXF1interactor400.236307.897NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain
Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding
TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain
LRR_8 (PF13855, IPR001611): Leucine rich repeat
144 OBSL1interactor360.38796.979BiPBP_C (PF06832, IPR009647): Penicillin-Binding Protein C-terminus Family
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Herpes_gE (PF02480, IPR003404): Alphaherpesvirus glycoprotein E
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
Ig_4 (PF16680, IPR032052): T-cell surface glycoprotein CD3 delta chain
Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
145 OXCT1interactor90.39312.955CoA_trans (PF01144, IPR004165, SM00882): Coenzyme A transferase
146 OXNAD1interactor100NAD_binding_1 (PF00175, IPR001433): Oxidoreductase NAD-binding domain
147 P4HBinteractor240.51425.001Glycos_trans_3N (PF02885, IPR017459): Glycosyl transferase family, helical bundle domain
Thioredoxin (PF00085, IPR013766): Thioredoxin
Thioredoxin_6 (PF13848): Thioredoxin-like domain
148 PACSIN2oncoprotein90.32112.737DegS (PF05384, IPR008595): Sensor protein DegS
FCH (PF00611, IPR001060, SM00055): Fes/CIP4, and EFC/F-BAR homology domain
SH3BP5 (PF05276, IPR007940): SH3 domain-binding protein 5 (SH3BP5)
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
NPF (PF16601): Rabosyn-5 repeating NPF sequence-motif
149 PACSIN3interactor100.5838.797FCH (PF00611, IPR001060, SM00055): Fes/CIP4, and EFC/F-BAR homology domain
GrpE (PF01025, IPR000740): GrpE
SH3_9 (PF14604, IPR001452): Variant SH3 domain
150 PAN2interactor160.42524.101RNase_T (PF00929, IPR013520): Exonuclease
UCH_1 (PF13423, IPR001394): Ubiquitin carboxyl-terminal hydrolase
WD40_like (PF17005, IPR031544): WD40-like domain
151 PARD3interactor21.0000PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
DUF3534 (PF12053, IPR021922): Domain of unknown function (DUF3534)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
152 PARK2suppressor380.336157.675IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
153 PCK1interactor50.4003.242PEPCK (PF00821, IPR008209): Phosphoenolpyruvate carboxykinase
154 PCK2interactor40.5000.456PEPCK (PF00821, IPR008209): Phosphoenolpyruvate carboxykinase
155 PDIA3interactor230.36474.305Thioredoxin (PF00085, IPR013766): Thioredoxin
Thioredoxin_6 (PF13848): Thioredoxin-like domain
156 PLCG2interactor21.0000C2 (PF00168, IPR000008, SM00239): C2 domain
EF-hand_like (PF09279, IPR015359): Phosphoinositide-specific phospholipase C, efhand-like
PH (PF00169, IPR001849, SM00233): PH domain
SH2 (PF00017, IPR000980, SM00252): SH2 domain
PI-PLC-X (PF00388, IPR000909, SM00148): Phosphatidylinositol-specific phospholipase C, X domain
PI-PLC-Y (PF00387, IPR001711, SM00149): Phosphatidylinositol-specific phospholipase C, Y domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
PH_12 (PF16457, IPR001849): Pleckstrin homology domain
157 PLGinteractor50.5004.115Kringle (PF00051, IPR000001): Kringle domain
PAN_1 (PF00024, IPR003014): PAN domain
Trypsin (PF00089, IPR001254, SM00020): Trypsin
158 PLOD3protein found in more fusions110.5336.4762OG-FeII_Oxy (PF03171, IPR005123): 2OG-Fe(II) oxygenase superfamily
Anp1 (PF03452, IPR005109): Anp1
159 PPA1interactor40.5000.245Pyrophosphatase (PF00719, IPR008162): Inorganic pyrophosphatase
160 PPP2R2Csuppressor21.0000WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
161 PRDM1suppressor50.5000.516SET (PF00856, IPR001214, SM00317): SET domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
162 PREPinteractor50.6000.840Peptidase_S9 (PF00326, IPR001375): Prolyl oligopeptidase family
Peptidase_S9_N (PF02897, IPR023302): Prolyl oligopeptidase, N-terminal beta-propeller domain
163 PSMA3interactor340.392101.978Proteasome (PF00227, IPR001353): Proteasome subunit
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
164 PTENsuppressor130.39717.991DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain
PTEN_C2 (PF10409, IPR014020): C2 domain of PTEN tumour-suppressor protein
165 PTMSinteractor60.4675.956Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family
U79_P34 (PF03064, IPR004138): HSV U79 / HCMV P34
166 PTPN2suppressor100Synaptobrevin (PF00957, IPR001388): Synaptobrevin
Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase
167 PUF60protein found in more fusions230.48526.644RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Titin_Z (PF09042, IPR015129): Titin Z
TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence
168 QTRT1interactor100TGT (PF01702, IPR002616): Queuine tRNA-ribosyltransferase
169 RAB1Boncoprotein60.5332.989Ras (PF00071, IPR001806, SM00173): Ras family
170 RAB5Boncoprotein70.3815.241Ras (PF00071, IPR001806, SM00173): Ras family
171 RAD52oncoprotein70.4673.283Rad52_Rad22 (PF04098, IPR007232): Rad52/22 family double-strand break repair protein
DUF2335 (PF10097, IPR019284): Predicted membrane protein (DUF2335)
172 RAF1oncoprotein150.51614.455Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
RBD (PF02196, IPR003116, SM00455): Raf-like Ras-binding domain
C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
173 REXO2interactor21.0000RNase_T (PF00929, IPR013520): Exonuclease
174 RFWD3interactor50.4002.430OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
zf-rbx1 (PF12678, IPR024766): RING-H2 zinc finger domain
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
175 RGS20interactor30.6671.000RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain
176 RPAP1interactor50.8000.194ATP-synt_B (PF00430, IPR002146): ATP synthase B/B' CF(0)
RPAP1_C (PF08620, IPR013929): RPAP1-like, C-terminal
RPAP1_N (PF08621, IPR013930): RPAP1-like, N-terminal
177 RPS6KB2interactor160.45811.144Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
178 SAMD3interactor100SAM_1 (PF00536, IPR021129, SM00454): SAM domain (Sterile alpha motif)
RecG_wedge (PF17191): RecG wedge domain
179 SAP30BPinteractor120.43914.260Dicty_REP (PF05086, IPR007778): Dictyostelium (Slime Mold) REP protein
HCNGP (PF07818, IPR012479): HCNGP-like protein
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
180 SARNPoncoprotein90.5564.638SAP (PF02037, IPR003034, SM00513): SAP domain
HTH_Tnp_IS630 (PF01710, IPR002622): Transposase
Prok-E2_A (PF14457, IPR032865): Prokaryotic E2 family A
181 SCARB2interactor21.0000CD36 (PF01130, IPR002159): CD36 family
182 SCARNA22interactor120.50014.431NA
183 SEPT9oncoprotein120.5615.740Septin (PF00735, IPR000038): Septin
DUF3306 (PF11748, IPR021735): Protein of unknown function (DUF3306)
184 SF3A2interactor180.52919.909Cytadhesin_P30 (PF07271, IPR009896): Cytadhesin P30/P32
PRP4 (PF08799, IPR014906): pre-mRNA processing factor 4 (PRP4) like
Totivirus_coat (PF05518, IPR008871): Totivirus coat protein
zf-met (PF12874): Zinc-finger of C2H2 type
ARL6IP6 (PF15062, IPR029383): Haemopoietic lineage transmembrane helix
SF3A2 (PF16835, IPR031781): Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11)
185 SIRT1suppressor150.35222.906DUF592 (PF04574, IPR007654): Protein of unknown function (DUF592)
SIR2 (PF02146, IPR003000): Sir2 family
TPP_enzyme_M (PF00205, IPR012000): Thiamine pyrophosphate enzyme, central domain
186 SIRT3suppressor60.4675.599SIR2 (PF02146, IPR003000): Sir2 family
187 SIRT4suppressor21.0000SIR2 (PF02146, IPR003000): Sir2 family
188 SKIoncoprotein100.6113.985c-SKI_SMAD_bind (PF08782, IPR014890, SM01046): c-SKI Smad4 binding domain
Ski_Sno (PF02437, IPR003380): SKI/SNO/DAC family
SlyX (PF04102, IPR007236): SlyX
HIP1_clath_bdg (PF16515, IPR032422): Clathrin-binding domain of Huntingtin-interacting protein 1
189 SLC25A33interactor100Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
190 SLC25A41interactor100Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
191 SMSinteractor70.4769.724Spermine_synth (PF01564, IPR001045): Spermine/spermidine synthase
192 SMURF1interactor190.40521.158C2 (PF00168, IPR000008, SM00239): C2 domain
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
193 SNW1protein found in more fusions430.332274.519SKIP_SNW (PF02731, IPR004015): SKIP/SNW domain
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
SIR4_SID (PF16991, IPR031556): Sir4 SID domain
194 SPG20interactor60.7330.311MIT (PF04212, IPR007330, SM00745): MIT (microtubule interacting and transport) domain
Senescence (PF06911, IPR009686): Senescence-associated protein
195 SRRM2interactor310.434103.980cwf21 (PF08312, IPR013170, SM01115): cwf21 domain
DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754)
Pap_E4 (PF02711, IPR003861): E4 protein
RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6
CTD (PF12815, IPR024945, SM01104): Spt5 C-terminal nonapeptide repeat binding Spt4
DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614)
196 STAU1protein found in more fusions250.57620.770dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
Staufen_C (PF16482, IPR032478): Staufen C-terminal domain
197 STRN4interactor70.5247.058CENP-H (PF05837, IPR008426): Centromere protein H (CENP-H)
K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
Striatin (PF08232, IPR013258): Striatin family
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
198 STUB1suppressor300.333116.670U-box (PF04564, IPR003613, SM00504): U-box domain
ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3
TPR_11 (PF13414, IPR011990): TPR repeat
TPR_20 (PF14561): Tetratricopeptide repeat
199 TANGO2interactor21.0000TANGO2 (PF05742, IPR008551): Transport and Golgi organisation 2
200 TAZinteractor30.6670.069Acyltransferase (PF01553, IPR002123, SM00563): Acyltransferase
201 THBS3oncoprotein200EGF (PF00008, IPR000742, SM00181): EGF-like domain
EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain
Laminin_G_2 (PF02210, IPR001791): Laminin G domain
TSP_3 (PF02412, IPR003367): Thrombospondin type 3 repeat
TSP_C (PF05735, IPR008859): Thrombospondin C-terminal region
COMP (PF11598, IPR024665): Cartilage oligomeric matrix protein
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
EGF_3 (PF12947, IPR024731): EGF domain
202 THOP1interactor60.6003.013Peptidase_M3 (PF01432, IPR001567): Peptidase family M3
203 TMCC2protein found in more fusions31.0000Tmemb_cc2 (PF10267, IPR019394): Predicted transmembrane and coiled-coil 2 protein
MAGE_N (PF12440, IPR021072): Melanoma associated antigen family N terminal
204 TRIM63interactor40.6670.222DUF349 (PF03993, IPR007139): Domain of Unknown Function (DUF349)
KIP1 (PF07765, IPR011684): KIP1-like protein
RED_C (PF07807, IPR012492): RED-like protein C-terminal region
zf-HIT (PF04438, IPR007529): HIT zinc finger
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger
YceG_bac (PF14266, IPR025647): Putative component of 'biosynthetic module'
205 TTC39Boncoprotein21.0000DUF3808 (PF10300, IPR019412): Protein of unknown function (DUF3808)
TPR_10 (PF13374, IPR011990): Tetratricopeptide repeat
TPR_12 (PF13424): Tetratricopeptide repeat
206 TUBA1Cinteractor320.40159.784Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
207 TUBB4Binteractor370.288106.901Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
208 TUBG1protein found in more fusions270.49231.747Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain
Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
209 TUBGCP3interactor170.58113.609Spc97_Spc98 (PF04130, IPR007259): Spc97 / Spc98 family
210 U2AF2protein found in more fusions390.454116.846RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Transformer (PF06495, IPR010519): Fruit fly transformer protein
211 UBCprotein found in more fusions580.278536.936ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
212 UBL4Ainteractor310.312125.334ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
213 UBR4interactor120.47012.123CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
Pheromone (PF08015, IPR012597): Fungal mating-type pheromone
RecR (PF02132, IPR023628): RecR protein
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box)
DZR (PF12773, IPR025874): Double zinc ribbon
E3_UbLigase_R4 (PF13764, IPR025704): E3 ubiquitin-protein ligase UBR4
FAM176 (PF14851): FAM176 family
214 UNKinteractor160.37522.189MbeD_MobD (PF04899, IPR006983): MbeD/MobD like
NUDE_C (PF04880, IPR006964): NUDE protein, C-terminal conserved region
zf-CCCH (PF00642, IPR000571): Zinc finger C-x8-C-x5-C-x3-H type (and similar)
DUF3450 (PF11932, IPR016866): Protein of unknown function (DUF3450)
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
zf-CCCH_2 (PF14608): RNA-binding, Nab2-type zinc finger
Torus (PF16131, IPR032297): Torus domain
215 VCAM1interactor290.40961.685C2-set (PF05790, IPR008424): Immunoglobulin C2-set domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
216 VCPprotein found in more fusions590.308417.037AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2
CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain
TniB (PF05621, IPR008868): Bacterial TniB protein
Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain
DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944)
217 XRCC3oncoprotein60.4672.629Rad51 (PF08423, IPR013632): Rad51
RNA_pol_A_CTD (PF03118, IPR011260): Bacterial RNA polymerase, alpha chain C terminal domain

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