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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins EBAG9, FAAH2 (from a repository: Sun Aug 11 13:46:02 2019)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)6
The number (and %) of the onco-proteins1 (16.67 %)
The number (and %) of the tumor suppressors1 (16.67 %)
Total number of binary PPIs (saturation %)7 (46.67 %)
The number (and %) of affected PPIs4 (57.14 %)
The number of possible different fusions3
PPI diameter4
PPI radius2
The average degree of PPI1.667
Assortativity coefficient-0.6124
The network average Clustering coefficient0.000
The number (and %) of a zero Clustering coefficients6 (100.00 %)
The number (and %) of a zero Betweenness Centrality3 (50.00 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: EBAG9,FAAH2 All fusions
Proteins found in more fusions NEDD4 (see 1 fusions); APP (see 5 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 EBAG9parental protein3014.000DUF3395 (PF11875, IPR024586): Domain of unknown function (DUF3395)
2 FAAH2parental protein100Amidase (PF01425, IPR000120): Amidase
3 APPprotein found in more fusions308.000APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding
Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP)
BUD22 (PF09073, IPR015158): BUD22
IncA (PF04156, IPR007285): IncA protein
Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus
APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
4 NEDD4suppressor200Rota_NS26 (PF01525, IPR002512): Rotavirus NS26
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
5 TMEM17interactor100Transmemb_17 (PF09799, IPR019184): Predicted membrane protein
DUF3043 (PF11241, IPR021403): Protein of unknown function (DUF3043)
6 TMEM216interactor2012.000Transmemb_17 (PF09799, IPR019184): Predicted membrane protein

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