Find Fusion Network

Visualization interactions

Powered by Cytoscape Web for: parental proteins DUSP18, CRIM1 (from a repository: Tue Jul 16 06:06:56 2019)

Examples AFF1 MLL ACTN4 + MLLAFF1 + MLLALK + MSNALK + TFGALK + TPM3ALK + TPM4ASXL2 + KAT6AATF1 + FUSBCR + ABL1BCR + FGFR1CCND1 + TACSTD2CD74 + ROS1CDK6 + MLLCOL1A1 + PDGFBCREB3L2 + PPARGCREB3L2 + FUSCREBBP + KAT6ADAZAP1 + MEF2DELL + MLLEPS15 + MLLERG + EWSR1ERG + FUSERG + TMPRSS2ETV5 + TMPRSS2ETV6 + ABL1ETV6 + NTRK3ETV6 + PAX5EWSR1 + FLI1EWSR1 + WT1FOXO1 + PAX3FOXP1 + PAX5FRYL + MLLGAS7 + MLLGMPS + MLLGOLGA5 + RETHOOK3 + RETHOXC13 + NUP98HOXD13 + NUP98MECOM + RUNX1MKL1 + RBM15MLL + MLLT1MLL + MLLT4MLL + MLLT10MLL + PICALMMLLT10 + PICALMNCOA1 + PAX3NIN + PDGFRBNPM1 + RARANRG1 + ODZ4NTRK1 + TFGNUMA1 + RARANUP98 + PHF23PAX5 + ZNF521PBX1 + TCF3RET + TRIM27ROS1 + SLC34A2PML + RARAPRKAR1A + RARAPRKAR1A + RETRUNX1 + RUNX1T1RUNX1 + SH3D19	Cytoscape Web will replace the contents your graph	PPI Properties: Click on nodes or edges
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Statistics and Network structure information

Statistic of PPI Value(s) The number of interactors (fusion and proteins) 5 The number (and %) of the onco-proteins 0 (0.00 %) The number (and %) of the tumor suppressors 0 (0.00 %) Total number of binary PPIs (saturation %) 4 (40.00 %) The number (and %) of affected PPIs 3 (75.00 %) The number of possible different fusions 1 PPI diameter 2 PPI radius inf The average degree of PPI 1.200 Assortativity coefficient 0 The network average Clustering coefficient 0.000 The number (and %) of a zero Clustering coefficients 5 (100.00 %) The number (and %) of a zero Betweenness Centrality 4 (80.00 %)

ACTIVE INTERACTORS

List of the fusions
PPI for parental proteins: DUSP18,CRIM1	All fusions
Proteins found in more fusions

List of active interactors

#	Name	Type	Number of PPI (degree)	Clustering Coefficient	Betweenness Centrality	Domains (Pfam, InterPro, SMART): description
1	DUSP18	parental protein	1	0	0	DSPc (PF00782, IPR020422, SM00195): Dual specificity phosphatase, catalytic domain
2	CRIM1	parental protein	2	0	2.000	Antistasin (PF02822, IPR004094): Antistasin family Rad50_zn_hook (PF04423, IPR007517): Rad50 zinc hook motif VWC (PF00093, IPR001007, SM00214): von Willebrand factor type C domain IGFBP (PF00219, IPR000867, SM00121): Insulin-like growth factor binding protein TILa (PF12714, IPR025615): TILa domain Amnionless (PF14828): Amnionless
3	ATXN7	interactor	1	0	0	DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180) SCA7 (PF08313, IPR013243): SCA7, zinc-binding domain Macoilin (PF09726, IPR019130): Transmembrane protein DUF3505 (PF12013, IPR022698): Protein of unknown function (DUF3505) IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal
4	CACNA1A	interactor	1	0	0	Ca_chan_IQ (PF08763, IPR014873, SM01062): Voltage gated calcium channel IQ domain GRP (PF07172, IPR010800): Glycine rich protein family Ion_trans (PF00520, IPR005821): Ion transport protein Roughex (PF06020, IPR009259): Drosophila roughex protein SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region GPHH (PF16905, IPR031649): Voltage-dependent L-type calcium channel, IQ-associated
5	MAPK8IP2	interactor	2	0	0	BUD22 (PF09073, IPR015158): BUD22 CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID) Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal SH3_9 (PF14604, IPR001452): Variant SH3 domain

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