Find Fusion Network

Enter
Fusion ID:
Protein names:


Level of PPIs:
or Upload text file:
Update repository
Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins CTNND1, PLSCR1 (from a repository: Tue Feb 14 21:38:29 2017)
Examples

Cytoscape Web will replace the contents your graph
PPI Properties:

Click on nodes
or edges

Layout Tree
Circle
Radial
Force Directed
Preset
Export graph
PDF file
SVG file
SIF file
XML file
GraphML file

Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)174
The number (and %) of the onco-proteins53 (30.46 %)
The number (and %) of the tumor suppressors17 (9.77 %)
Total number of binary PPIs (saturation %)794 (5.28 %)
The number (and %) of affected PPIs175 (22.04 %)
The number of possible different fusions32
PPI diameter4
PPI radius2
The average degree of PPI8.379
Assortativity coefficient-0.3102
The network average Clustering coefficient0.454
The number (and %) of a zero Clustering coefficients24 (13.79 %)
The number (and %) of a zero Betweenness Centrality46 (26.44 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: PLSCR1,CTNND1 All fusions
Proteins found in more fusions AP2M1 (see 3 fusions); EWSR1/MED15 (see 3 fusions); PTPRJ (see 2 fusions); APP (see 4 fusions); VCP (see 4 fusions); NTRK1/TFG (see 1 fusions); FBLN1 (see 3 fusions); CTNNA1 (see 3 fusions); FRS3 (see 1 fusions); CUL3 (see 1 fusions); SQSTM1 (see 5 fusions); LCK (see 1 fusions); FYN (see 1 fusions); MYC (see 1 fusions); CDH1 (see 3 fusions); EWSR1 (see 2 fusions); SF1 (see 1 fusions); ZNF638/CDC5L (see 1 fusions); ERBIN (see 4 fusions); ACTG1 (see 4 fusions); EGFR (see 2 fusions); MCM2 (see 1 fusions); CTTN (see 1 fusions); ATN1 (see 1 fusions); SHC1 (see 1 fusions); SMARCC1 (see 2 fusions); EP300 (see 1 fusions); DAZAP2 (see 2 fusions); PML (see 4 fusions); ZBTB16 (see 3 fusions); CSNK1E (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 PLSCR1parental protein1230.03818383.345Scramblase (PF03803, IPR005552): Scramblase
2 CTNND1parental protein520.1143253.969Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
Ebp2 (PF05890, IPR008610): Eukaryotic rRNA processing protein EBP2
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
3 ACTG1protein found in more fusions120.20086.148Actin (PF00022, IPR004000, SM00268): Actin
4 ADAMTSL4interactor300.276286.213ADAM_spacer1 (PF05986, IPR010294): ADAM-TS Spacer 1
PLAC (PF08686, IPR010909, SM00022): PLAC (protease and lacunin) domain
TSP_1 (PF00090, IPR000884, SM00209): Thrombospondin type 1 domain
Zn_ribbon_17 (PF17120): Zinc-ribbon, C4HC2 type
5 ADCY7interactor100DUF1053 (PF06327, IPR009398): Domain of Unknown Function (DUF1053)
Guanylate_cyc (PF00211, IPR001054, SM00044): Adenylate and Guanylate cyclase catalytic domain
AC_N (PF16214, IPR032628): Adenylyl cyclase N-terminal extracellular and transmembrane region
DUF4956 (PF16316, IPR032531): Domain of unknown function (DUF4956)
6 ANXA11interactor70.333167.599Annexin (PF00191, IPR018502, SM00335): Annexin
7 AP2M1protein found in more fusions140.321151.408Adap_comp_sub (PF00928, IPR008968): Adaptor complexes medium subunit family
Clat_adaptor_s (PF01217, IPR022775): Clathrin adaptor complex small chain
8 APPprotein found in more fusions300.1081886.511APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding
Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP)
BUD22 (PF09073, IPR015158): BUD22
IncA (PF04156, IPR007285): IncA protein
Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus
APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
9 ARNT2interactor60.53315.117HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
PAS (PF00989, IPR013767, SM00091): PAS fold
PAS_3 (PF08447, IPR013655): PAS fold
PAP2 (PF01569, IPR000326, SM00014): PAP2 superfamily
10 ARRB2interactor100.44417.852Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain
Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain
11 ATF2oncoprotein80.52410.930bZIP_1 (PF00170, IPR004827): bZIP transcription factor
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
12 ATG12interactor40.33327.642APG12 (PF04110, IPR007242): Ubiquitin-like autophagy protein Apg12
13 ATN1protein found in more fusions80.38115.990Atrophin-1 (PF03154, IPR002951): Atrophin-1 family
14 ATP4Ainteractor4026.063Cation_ATPase_C (PF00689, IPR006068): Cation transporting ATPase, C-terminus
Cation_ATPase_N (PF00690, IPR004014, SM00831): Cation transporter/ATPase, N-terminus
E1-E2_ATPase (PF00122, IPR008250): E1-E2 ATPase
H-K_ATPase_N (PF09040, IPR015127): Gastric H+/K+-ATPase, N terminal domain
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
HAD (PF12710): haloacid dehalogenase-like hydrolase
Cation_ATPase (PF13246): Cation transport ATPase (P-type)
15 AURKAoncoprotein90.25052.670Pkinase (PF00069, IPR000719): Protein kinase domain
MTBP_C (PF14920, IPR029418): MDM2-binding
16 BCL6Bsuppressor31.0000BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
Lar_restr_allev (PF14354): Restriction alleviation protein Lar
17 BMI1oncoprotein120.291105.611zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
RAWUL (PF16207, IPR032443): RAWUL domain RING finger- and WD40-associated ubiquitin-like
18 C10orf10interactor100DEPP (PF15343, IPR020133): Decidual protein induced by progesterone family
19 C10orf54interactor100V-set (PF07686, IPR013106): Immunoglobulin V-set domain
20 C10orf62interactor41.0000NA
21 CATSPER1interactor140.56418.418Ion_trans (PF00520, IPR005821): Ion transport protein
MMM1 (PF10296, IPR019411): Maintenance of mitochondrial morphology protein 1
22 CCDC33interactor80.50045.214C2 (PF00168, IPR000008, SM00239): C2 domain
DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972)
Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat
SlyX (PF04102, IPR007236): SlyX
23 CCDC8interactor180.199220.503Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
PNMA (PF14893, IPR026523): PNMA
24 CCER1interactor21.0000Vfa1 (PF08432, IPR013640): AAA-ATPase Vps4-associated protein 1
Neugrin (PF06413, IPR010487): Neugrin
CCER1 (PF15482, IPR027889): Coiled-coil domain-containing glutamate-rich protein family 1
25 CDC42EP1oncoprotein50.200102.935DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
FAP (PF07174, IPR010801): Fibronectin-attachment protein (FAP)
PBD (PF00786, IPR000095, SM00285): P21-Rho-binding domain
BORG_CEP (PF14957, IPR029273): Cdc42 effector
26 CDC5Lprotein found in more fusions100.25084.625OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
Pox_A_type_inc (PF04508, IPR007596): Viral A-type inclusion protein repeat
Cir_N (PF10197, IPR019339, SM01083): N-terminal domain of CBF1 interacting co-repressor CIR
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
Myb_Cef (PF11831, IPR021786): pre-mRNA splicing factor component
Myb_DNA-bind_6 (PF13921): Myb-like DNA-binding domain
27 CDH1suppressor130.39463.479Cadherin_C (PF01049, IPR000233): Cadherin cytoplasmic region
Cadherin_pro (PF08758, IPR014868, SM01055): Cadherin prodomain like
Cadherin (PF00028, IPR002126, SM00112): Cadherin domain
28 CDH2interactor41.0000Cadherin_C (PF01049, IPR000233): Cadherin cytoplasmic region
Cadherin_pro (PF08758, IPR014868, SM01055): Cadherin prodomain like
Cadherin (PF00028, IPR002126, SM00112): Cadherin domain
EphA2_TM (PF14575, IPR027936): Ephrin type-A receptor 2 transmembrane domain
Cadherin_3 (PF16184): Cadherin-like
29 CDH3interactor60.9000.420Cadherin_C (PF01049, IPR000233): Cadherin cytoplasmic region
Cadherin_pro (PF08758, IPR014868, SM01055): Cadherin prodomain like
LSR (PF05624, IPR008664): Lipolysis stimulated receptor (LSR)
DUF2207 (PF09972, IPR018702): Predicted membrane protein (DUF2207)
Cadherin (PF00028, IPR002126, SM00112): Cadherin domain
Cadherin_3 (PF16184): Cadherin-like
30 CDH5suppressor60.5334.366Cadherin_C (PF01049, IPR000233): Cadherin cytoplasmic region
Cadherin (PF00028, IPR002126, SM00112): Cadherin domain
31 CEP135interactor21.0000DUF724 (PF05266, IPR007930): Protein of unknown function (DUF724)
ERM (PF00769, IPR011259): Ezrin/radixin/moesin family
LPP (PF04728, IPR006817): Lipoprotein leucine-zipper
RasGAP_C (PF03836, IPR000593): RasGAP C-terminus
Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein
TPD52 (PF04201, IPR007327): Tumour protein D52 family
CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
zf-C4H2 (PF10146, IPR018482): Zinc finger-containing protein
KASH_CCD (PF14662, IPR028168): Coiled-coil region of CCDC155 or KASH
HMMR_N (PF15905, IPR031787): Hyaluronan mediated motility receptor N-terminal
GIT_CC (PF16559, IPR032352): GIT coiled-coil Rho guanine nucleotide exchange factor
PKcGMP_CC (PF16808, IPR031831): Coiled-coil N-terminus of cGMP-dependent protein kinase
32 CHRDinteractor110.49125.414CHRD (PF07452, IPR010895, SM00754): CHRD domain
VWC (PF00093, IPR001007, SM00214): von Willebrand factor type C domain
33 CNTFRinteractor21.0000fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Ig_3 (PF13927): Immunoglobulin domain
CBP_CCPA (PF17040, IPR031480): Cellulose-complementing protein A
34 COL17A1interactor21.0000Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
DUF2868 (PF11067, IPR021296): Protein of unknown function (DUF2868)
Edc3_linker (PF16598): Linker region of enhancer of mRNA-decapping protein 3
35 CPSF3Linteractor2066.374RMMBL (PF07521, IPR011108): Zn-dependent metallo-hydrolase RNA specificity domain
Beta-Casp (PF10996, IPR022712, SM01027): Beta-Casp domain
Lactamase_B_3 (PF13483): Beta-lactamase superfamily domain
Lactamase_B_6 (PF16661, IPR001279): Metallo-beta-lactamase superfamily domain
36 CPSF6interactor70.52478.070RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
PRIMA1 (PF16101): Proline-rich membrane anchor 1
37 CRKoncoprotein70.52461.641SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_2 (PF07653, IPR011511): Variant SH3 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
38 CRKLoncoprotein80.357131.771SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_2 (PF07653, IPR011511): Variant SH3 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
39 CRY1interactor70.333141.052DNA_photolyase (PF00875, IPR006050): DNA photolyase
FAD_binding_7 (PF03441, IPR005101): FAD binding domain of DNA photolyase
40 CSNK1Eprotein found in more fusions70.60015.826APH (PF01636, IPR002575): Phosphotransferase enzyme family
Pkinase (PF00069, IPR000719): Protein kinase domain
41 CTBP1-AS2interactor100NA
42 CTNNA1oncoprotein170.375135.657Vinculin (PF01044, IPR006077): Vinculin family
43 CTNNB1oncoprotein280.206648.935Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361)
HEAT_EZ (PF13513): HEAT-like repeat
44 CTSZinteractor100Peptidase_C1 (PF00112, IPR000668, SM00645): Papain family cysteine protease
45 CTTNoncoprotein110.44430.190FadA (PF09403, IPR018543): Adhesion protein FadA
HS1_rep (PF02218, IPR003134): Repeat in HS1/Cortactin
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
46 CUL3protein found in more fusions250.203584.333Cullin (PF00888, IPR001373, SM00182): Cullin family
Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
WAC_Acf1_DNA_bd (PF10537, IPR013136): ATP-utilising chromatin assembly and remodelling N-terminal
47 DAZAP2protein found in more fusions90.179220.524DAZAP2 (PF11029, IPR022730): DAZ associated protein 2 (DAZAP2)
48 DEF6interactor30.6672.465ArgK (PF03308, IPR005129): ArgK protein
HSP70 (PF00012, IPR013126): Hsp70 protein
PH (PF00169, IPR001849, SM00233): PH domain
zf-C4H2 (PF10146, IPR018482): Zinc finger-containing protein
EF-hand_6 (PF13405, IPR002048): EF-hand domain
49 DHRS1interactor21.0000adh_short (PF00106, IPR002198): short chain dehydrogenase
50 DLK2interactor40.6675.206EGF (PF00008, IPR000742, SM00181): EGF-like domain
Laminin_EGF (PF00053, IPR002049, SM00180): Laminin EGF domain
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
51 DMRT3interactor40.6671.500DM (PF00751, IPR001275, SM00301): DM DNA binding domain
DMA (PF03474, IPR005173): DMRTA motif
Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator
52 DOCK2oncoprotein70.61925.531DHR-2 (PF06920, IPR010703): Dock homology region 2
DUF1539 (PF07560, IPR011436): Domain of Unknown Function (DUF1539)
DOCK-C2 (PF14429, IPR027007): C2 domain in Dock180 and Zizimin proteins
SH3_9 (PF14604, IPR001452): Variant SH3 domain
DOCK_N (PF16172, IPR032376): DOCK N-terminus
53 DTX2oncoprotein40.3339.945WWE (PF02825, IPR004170, SM00678): WWE domain
zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
zf-UDP (PF14569, IPR027934): Zinc-binding RING-finger
54 EFEMP2interactor120.22740.116EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain
hEGF (PF12661, IPR013032): Human growth factor-like EGF
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
Adipogenin (PF15202, IPR027938): Adipogenin
55 EGFRoncoprotein270.2221748.985Furin-like (PF00757, IPR006211): Furin-like cysteine rich region
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
Recep_L_domain (PF01030, IPR000494): Receptor L domain
GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT)
GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
56 ENKD1interactor30.33319.289Enkurin (PF13864, IPR027012): Calmodulin-binding
57 EP300oncoprotein160.171580.906Creb_binding (PF09030, IPR014744): Creb binding
DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902)
Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
KIX (PF02172, IPR003101): KIX domain
RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6
TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2)
zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger
HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
58 ERBINoncoprotein70.5338.217LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
Neur_chan_memb (PF02932, IPR006029): Neurotransmitter-gated ion-channel transmembrane region
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
59 ESR2suppressor40.6670.667zf-C4 (PF00105, IPR001628, SM00399): Zinc finger, C4 type (two domains)
Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
ERbeta_N (PF12497, IPR021064): Estrogen receptor beta
60 EWSR1oncoprotein230.190648.191RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
SVS_QK (PF10578, IPR018942): Seminal vesicle protein repeat
zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
Keratin_2_head (PF16208, IPR032444): Keratin type II head
61 EXD3interactor31.0000DNA_pol_A_exo1 (PF01612, IPR002562, SM00474): 3'-5' exonuclease
Mut7-C (PF01927, IPR002782): Mut7-C RNAse domain
62 FAM103A1interactor30.33340.351RAM (PF15320, IPR028271): mRNA cap methylation, RNMT-activating mini protein
63 FAM134Cinteractor2014.842Reticulon (PF02453, IPR003388): Reticulon
64 FBLN1suppressor60.40020.729ANATO (PF01821, IPR000020, SM00104): Anaphylotoxin-like domain
EGF (PF00008, IPR000742, SM00181): EGF-like domain
EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site
65 FBXL18interactor40.50028.308LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
F-box (PF00646, IPR001810, SM00256): F-box domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
66 FOXB1interactor40.500150.518Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
67 FRAT1oncoprotein100GSK-3_bind (PF05350, IPR008014): Glycogen synthase kinase-3 binding
68 FRS3suppressor50.6672.613IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type)
69 FYNoncoprotein80.5718.407Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
70 GDE1interactor100GDPD (PF03009, IPR004129): Glycerophosphoryl diester phosphodiesterase family
71 GDPD5interactor100DUF1049 (PF06305, IPR010445): Protein of unknown function (DUF1049)
GDPD (PF03009, IPR004129): Glycerophosphoryl diester phosphodiesterase family
MgtE (PF01769, IPR006667): Divalent cation transporter
GDPD_2 (PF13653): Glycerophosphoryl diester phosphodiesterase family
72 GLRX3interactor170.408210.499Glutaredoxin (PF00462, IPR002109): Glutaredoxin
Thioredoxin (PF00085, IPR013766): Thioredoxin
TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding
73 GNAI2oncoprotein40.167111.288G-alpha (PF00503, IPR001019, SM00275): G-protein alpha subunit
74 GPRIN2interactor41.0000GRIN_C (PF15235, IPR032745): G protein-regulated inducer of neurite outgrowth C-terminus
75 HEY2interactor100Hairy_orange (PF07527, IPR003650): Hairy Orange
HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence
76 HOXA1interactor170.46735.833Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
77 HOXA9oncoprotein100Hox9_act (PF04617, IPR006711): Hox9 activation region
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
78 HOXB6interactor100Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
79 HRGsuppressor21.0000Cystatin (PF00031, IPR000010, SM00043): Cystatin domain
80 IFI16suppressor80.17990.056HIN (PF02760, IPR004021): HIN-200/IF120x domain
PYRIN (PF02758, IPR004020): PAAD/DAPIN/Pyrin domain
Mitofilin (PF09731, IPR019133): Mitochondrial inner membrane protein
81 ILF3oncoprotein160.183449.907dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif
DZF (PF07528, IPR006561, SM00572): DZF domain
82 IP6K2interactor100IPK (PF03770, IPR005522): Inositol polyphosphate kinase
83 KCTD6interactor31.0000BTB_2 (PF02214, IPR003131): BTB/POZ domain
84 KIAA1683interactor100IQ (PF00612, IPR000048, SM00015): IQ calmodulin-binding motif
85 KIF1Ainteractor50.50053.576FHA (PF00498, IPR000253, SM00240): FHA domain
IncA (PF04156, IPR007285): IncA protein
PH (PF00169, IPR001849, SM00233): PH domain
Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein
Kinesin (PF00225, IPR001752, SM00129): Kinesin motor domain
KIF1B (PF12423, IPR022140): Kinesin protein 1B
Sox_N (PF12444, IPR022151): Sox developmental protein N terminal
DUF3694 (PF12473, IPR022164): Kinesin protein
Kinesin_assoc (PF16183, IPR032405): Kinesin-associated
86 KRTAP10-11interactor80.7501.657Keratin_B2 (PF01500, IPR002494): Keratin, high sulfur B2 protein
Keratin_B2_2 (PF13885, IPR002494): Keratin, high sulfur B2 protein
87 KRTAP10-3interactor400.185720.567Keratin_B2 (PF01500, IPR002494): Keratin, high sulfur B2 protein
Keratin_B2_2 (PF13885, IPR002494): Keratin, high sulfur B2 protein
88 KRTAP10-9interactor320.297181.365Keratin_B2_2 (PF13885, IPR002494): Keratin, high sulfur B2 protein
89 KRTAP4-11interactor90.7222.746Keratin_B2 (PF01500, IPR002494): Keratin, high sulfur B2 protein
Keratin_B2_2 (PF13885, IPR002494): Keratin, high sulfur B2 protein
90 KRTAP4-12interactor360.165576.623Keratin_B2_2 (PF13885, IPR002494): Keratin, high sulfur B2 protein
91 KRTAP4-2interactor180.43848.088Keratin_B2_2 (PF13885, IPR002494): Keratin, high sulfur B2 protein
92 KRTAP5-6interactor120.7883.678NA
93 KRTAP9-2interactor190.542105.696Keratin_B2_2 (PF13885, IPR002494): Keratin, high sulfur B2 protein
94 LASP1oncoprotein70.19070.389LIM (PF00412, IPR001781, SM00132): LIM domain
Nebulin (PF00880, IPR000900, SM00227): Nebulin repeat
SH3_9 (PF14604, IPR001452): Variant SH3 domain
95 LCE2Dinteractor80.7621.394LCE (PF14672, IPR028205): Late cornified envelope
96 LCE3Cinteractor70.7142.305LCE (PF14672, IPR028205): Late cornified envelope
97 LCE4Ainteractor90.8061.614LCE (PF14672, IPR028205): Late cornified envelope
98 LCKoncoprotein40.6671.400Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
99 LGALS9Cinteractor100Gal-bind_lectin (PF00337, IPR001079, SM00908): Galactoside-binding lectin
100 LINC00663interactor21.0000NA
101 LINC01547interactor100NA
102 LONRF1interactor50.8330.333LON_substr_bdg (PF02190, IPR003111, SM00464): ATP-dependent protease La (LON) substrate-binding domain
TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
DZR (PF12773, IPR025874): Double zinc ribbon
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_14 (PF13428): Tetratricopeptide repeat
zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
TPR_19 (PF14559): Tetratricopeptide repeat
zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
103 MAPK6oncoprotein80.238100.148Pkinase (PF00069, IPR000719): Protein kinase domain
104 MCM2oncoprotein200.216414.845AAA_3 (PF07726, IPR011703): ATPase family associated with various cellular activities (AAA)
MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family
MCM2_N (PF12619, IPR008045): Mini-chromosome maintenance protein 2
MCM_N (PF14551, IPR027925): MCM N-terminal domain
MCM_OB (PF17207): MCM OB domain
105 MED15protein found in more fusions21.0000Med15 (PF09606, IPR019087): ARC105 or Med15 subunit of Mediator complex non-fungal
106 MGAT5Binteractor50.4005.016Glyco_transf_18 (PF15024): Glycosyltransferase family 18
107 MUC1oncoprotein40.8330.286SEA (PF01390, IPR000082, SM00200): SEA domain
Shisa (PF13908, IPR026910): Wnt and FGF inhibitory regulator
Collectrin (PF16959, IPR031588): Renal amino acid transporter
108 MVPoncoprotein60.30057.136Vault (PF01505, IPR002499): Major Vault Protein repeat
DUF2543 (PF10820, IPR020251): Protein of unknown function (DUF2543)
MVP_shoulder (PF11978, IPR021870): Shoulder domain
109 MYConcoprotein150.220151.710HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
Myc-LZ (PF02344, IPR003327): Myc leucine zipper domain
Myc_N (PF01056, IPR012682): Myc amino-terminal region
110 NECAP2interactor30.33331.866DUF1681 (PF07933, IPR012466): Protein of unknown function (DUF1681)
111 NEU4interactor100BNR_2 (PF13088, IPR011040): BNR repeat-like domain
112 NOC4Linteractor30.33329.063CBF (PF03914, IPR005612, SM00521): CBF/Mak21 family
113 NPDC1interactor41.0000NPDC1 (PF06809, IPR009635): Neural proliferation differentiation control-1 protein (NPDC1)
114 NR0B2suppressor30.6673.525Hormone_recep (PF00104, IPR000536, SM00430): Ligand-binding domain of nuclear hormone receptor
115 NTN4interactor30.33320.202EGF_2 (PF07974, IPR013111): EGF-like domain
NTR (PF01759, IPR018933, SM00206): UNC-6/NTR/C345C module
Laminin_EGF (PF00053, IPR002049, SM00180): Laminin EGF domain
Laminin_N (PF00055, IPR008211, SM00136): Laminin N-terminal (Domain VI)
116 NTRK1oncoprotein360.1481212.221I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
117 NXF1interactor170.158302.689NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain
Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding
TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain
LRR_8 (PF13855, IPR001611): Leucine rich repeat
118 OGDHinteractor3029.818E1_dh (PF00676, IPR001017): Dehydrogenase E1 component
Transket_pyr (PF02779, IPR005475, SM00861): Transketolase, pyrimidine binding domain
2-oxogl_dehyd_N (PF16078, IPR032106): 2-oxoglutarate dehydrogenase N-terminus
OxoGdeHyase_C (PF16870, IPR031717): 2-oxoglutarate dehydrogenase C-terminal
119 OTUB1interactor50.40015.030Peptidase_C65 (PF10275, IPR019400): Peptidase C65 Otubain
120 P2RY6interactor21.00007tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
121 PCED1Ainteractor21.0000PC-Esterase (PF13839, IPR026057): GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p
122 PGLSinteractor60.53349.600Glucosamine_iso (PF01182, IPR006148): Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
123 PHLDA1oncoprotein40.6678.900Pex14_N (PF04695, IPR006785): Peroxisomal membrane anchor protein (Pex14p) conserved region
PH (PF00169, IPR001849, SM00233): PH domain
Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP)
TonB_N (PF16031): TonB N-terminal region
124 PITX1oncoprotein40.33337.422Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
OAR (PF03826, IPR003654): OAR domain
Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
125 PKD2interactor31.0000Ion_trans (PF00520, IPR005821): Ion transport protein
PKD_channel (PF08016, IPR013122): Polycystin cation channel
Tetraspannin (PF00335, IPR018499): Tetraspanin family
EF-hand_1 (PF00036, IPR002048, SM00054): EF hand
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
126 PLSCR3interactor30.6670.286Scramblase (PF03803, IPR005552): Scramblase
127 PLSCR4interactor40.5001.389Scramblase (PF03803, IPR005552): Scramblase
128 PMLsuppressor130.197404.956zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
DUF3583 (PF12126, IPR021978): Protein of unknown function (DUF3583)
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
129 PPP4R1interactor31.0000HEAT (PF02985, IPR000357): HEAT repeat
Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
HEAT_2 (PF13646): HEAT repeats
WRNPLPNID (PF15017): Putative WW-binding domain and destruction box
130 PRR13interactor40.6670.993DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755)
131 PSEN1oncoprotein60.9002.928Presenilin (PF01080, IPR001108): Presenilin
LRRC37AB_C (PF14914, IPR029423): LRRC37A/B like protein 1 C-terminal domain
132 PTPN6suppressor30.66721.040SH2 (PF00017, IPR000980, SM00252): SH2 domain
Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase
PolyA_pol_arg_C (PF12626, IPR025866): Polymerase A arginine-rich C-terminus
133 PTPRJsuppressor41.0000fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Interfer-bind (PF09294, IPR015373): Interferon-alpha/beta receptor, fibronectin type III
Syndecan (PF01034, IPR027789): Syndecan domain
Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase
134 PTPRMinteractor100fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
ig (PF00047, IPR013151, SM00409): Immunoglobulin domain
MAM (PF00629, IPR000998, SM00137): MAM domain, meprin/A5/mu
Y_phosphatase (PF00102, IPR000242, SM00194): Protein-tyrosine phosphatase
ECSCR (PF15820, IPR026247): Endothelial cell-specific chemotaxis regulator
135 RASD1interactor100Arf (PF00025, IPR006689, SM00177): ADP-ribosylation factor family
Ras (PF00071, IPR001806, SM00173): Ras family
136 RBL1suppressor40.33346.869RB_A (PF01858, IPR002720): Retinoblastoma-associated protein A domain
RB_B (PF01857, IPR002719): Retinoblastoma-associated protein B domain
Rb_C (PF08934, IPR015030): Rb C-terminal domain
DUF3452 (PF11934, IPR024599): Domain of unknown function (DUF3452)
137 REREoncoprotein50.6008.430Atrophin-1 (PF03154, IPR002951): Atrophin-1 family
BAH (PF01426, IPR001025, SM00439): BAH domain
ELM2 (PF01448, IPR000949): ELM2 domain
POPLD (PF08170, IPR012590): POPLD (NUC188) domain
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
GATA (PF00320, IPR000679, SM00401): GATA zinc finger
138 RGS3oncoprotein30.6673.408C2 (PF00168, IPR000008, SM00239): C2 domain
CDC45 (PF02724, IPR003874): CDC45-like protein
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
RGS (PF00615, IPR000342, SM00315): Regulator of G protein signaling domain
Astro_capsid_p (PF12226, IPR022027): Turkey astrovirus capsid protein
139 RIPK3interactor100Pkinase (PF00069, IPR000719): Protein kinase domain
TrbM (PF07424, IPR009989): TrbM
MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
RHIM (PF12721, IPR025735): RIP homotypic interaction motif
140 SCNM1interactor50.8001.086zf-SCNM1 (PF15803, IPR031622): Zinc-finger of sodium channel modifier 1
SCNM1_acidic (PF15805, IPR031625): Acidic C-terminal region of sodium channel modifier 1 SCNM1
141 SF1protein found in more fusions80.52459.773UPF0181 (PF03701, IPR005371): Uncharacterised protein family (UPF0181)
zf-CCHC (PF00098, IPR001878): Zinc knuckle
KH_1 (PF00013, IPR004088, SM00322): KH domain
RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein
PRIMA1 (PF16101): Proline-rich membrane anchor 1
SF1-HH (PF16275, IPR032570): Splicing factor 1 helix-hairpin domain
142 SHC1oncoprotein140.269288.552PID (PF00640, IPR006020, SM00462): Phosphotyrosine interaction domain (PTB/PID)
SH2 (PF00017, IPR000980, SM00252): SH2 domain
143 SLC25A6interactor70.238130.983Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
144 SLC35A2interactor21.0000Nuc_sug_transp (PF04142, IPR007271): Nucleotide-sugar transporter
145 SLPIinteractor100BES1_N (PF05687, IPR008540): BES1/BZR1 plant transcription factor, N-terminal
WAP (PF00095, IPR008197, SM00217): WAP-type (Whey Acidic Protein) 'four-disulfide core'
146 SMARCC1suppressor130.273381.760SWIRM (PF04433, IPR007526): SWIRM domain
Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
DUF2618 (PF10940, IPR021237): Protein of unknown function (DUF2618)
PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated
SWIRM-assoc_1 (PF16495, IPR032451): SWIRM-associated region 1
SWIRM-assoc_2 (PF16496, IPR032450): SWIRM-associated domain at the N-terminal
SWIRM-assoc_3 (PF16498, IPR032448): SWIRM-associated domain at the C-terminal
147 SMCPinteractor80.7861.750DUF2650 (PF10853, IPR022559): Protein of unknown function (DUF2650)
148 SNCAinteractor80.38119.922Synuclein (PF01387, IPR001058): Synuclein
149 SOX2oncoprotein70.33367.326HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
SOXp (PF12336, IPR022097): SOX transcription factor
150 SPATA8interactor51.0000NA
151 SPG7oncoprotein50.7003.206AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
FtsH_ext (PF06480, IPR011546): FtsH Extracellular
Peptidase_M41 (PF01434, IPR000642): Peptidase family M41
AAA_22 (PF13401, IPR003593): AAA domain
152 SPRY2suppressor240.320116.862KAR9 (PF08580, IPR013889): Yeast cortical protein KAR9
Sprouty (PF05210, IPR007875): Sprouty protein (Spry)
153 SQSTM1oncoprotein140.256239.022PB1 (PF00564, IPR000270, SM00666): PB1 domain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
UBA_5 (PF16577, IPR015940): UBA domain
154 SRConcoprotein130.303637.664Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
155 STK16interactor110.44417.024Pkinase (PF00069, IPR000719): Protein kinase domain
156 SUMO2interactor70.26720.086Rad60-SLD (PF11976, IPR022617): Ubiquitin-2 like Rad60 SUMO-like
157 TFGoncoprotein100.278287.891ARS2 (PF04959, IPR007042): Arsenite-resistance protein 2
MucBP (PF06458, IPR009459): MucBP domain
PB1 (PF00564, IPR000270, SM00666): PB1 domain
TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit
158 TMEM17interactor50.30014.305Transmemb_17 (PF09799, IPR019184): Predicted membrane protein
DUF3043 (PF11241, IPR021403): Protein of unknown function (DUF3043)
159 TMEM216interactor21.0000Transmemb_17 (PF09799, IPR019184): Predicted membrane protein
160 TRIM42interactor150.42943.268CHDCT2 (PF08074, IPR012957): CHDCT2 (NUC038) domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger
161 VASPinteractor60.20092.257ASD2 (PF08687, IPR014799): Apx/Shroom domain ASD2
CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
VASP_tetra (PF08776, IPR014885): VASP tetramerisation domain
WH1 (PF00568, IPR000697, SM00461): WH1 domain
162 VCPprotein found in more fusions110.37856.807AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2
CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain
TniB (PF05621, IPR008868): Bacterial TniB protein
Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain
DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944)
163 VPS37Cinteractor40.5002.900Mod_r (PF07200, IPR009851): Modifier of rudimentary (Mod(r)) protein
164 WDR48suppressor40.6675.658WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
DUF3337 (PF11816, IPR021772): Domain of unknown function (DUF3337)
165 XPO1interactor250.167567.273CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
166 YES1oncoprotein60.4679.122Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
SH2 (PF00017, IPR000980, SM00252): SH2 domain
YdjC (PF04794, IPR006879): YdjC-like protein
SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
167 YIPF3interactor21.0000Yip1 (PF04893, IPR006977): Yip1 domain
DUF4133 (PF13571, IPR025407): Domain of unknown function (DUF4133)
168 ZBTB16suppressor70.40046.381BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger
169 ZBTB33oncoprotein60.46719.776BTB (PF00651, IPR013069, SM00225): BTB/POZ domain
HD-ZIP_N (PF04618, IPR006712): HD-ZIP protein N terminus
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
170 ZNF417interactor80.8571.082A2L_zn_ribbon (PF08792, IPR014900): A2L zinc ribbon domain
C1_4 (PF07975, IPR004595, SM01047): TFIIH C1-like domain
KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
171 ZNF581interactor70.52426.469zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
172 ZNF587interactor61.0000KRAB (PF01352, IPR001909, SM00349): KRAB box
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger
173 ZNF638protein found in more fusions60.133119.410RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
zf-met (PF12874): Zinc-finger of C2H2 type
Ferlin_C (PF16165, IPR032362): Ferlin C-terminus
174 ZNF764interactor21.0000KRAB (PF01352, IPR001909, SM00349): KRAB box
PHD (PF00628, IPR019787, SM00249): PHD-finger
zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type
DUF2256 (PF10013, IPR017136): Uncharacterized protein conserved in bacteria (DUF2256)
zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
zf-C2H2_4 (PF13894): C2H2-type zinc finger

B a c k    t o    T o p ⇑