Find Fusion Network

Visualization interactions

Powered by Cytoscape Web for: parental proteins NF2, CTBP1 (from a repository: Sun Jul 14 21:36:23 2019)

Examples AFF1 MLL ACTN4 + MLLAFF1 + MLLALK + MSNALK + TFGALK + TPM3ALK + TPM4ASXL2 + KAT6AATF1 + FUSBCR + ABL1BCR + FGFR1CCND1 + TACSTD2CD74 + ROS1CDK6 + MLLCOL1A1 + PDGFBCREB3L2 + PPARGCREB3L2 + FUSCREBBP + KAT6ADAZAP1 + MEF2DELL + MLLEPS15 + MLLERG + EWSR1ERG + FUSERG + TMPRSS2ETV5 + TMPRSS2ETV6 + ABL1ETV6 + NTRK3ETV6 + PAX5EWSR1 + FLI1EWSR1 + WT1FOXO1 + PAX3FOXP1 + PAX5FRYL + MLLGAS7 + MLLGMPS + MLLGOLGA5 + RETHOOK3 + RETHOXC13 + NUP98HOXD13 + NUP98MECOM + RUNX1MKL1 + RBM15MLL + MLLT1MLL + MLLT4MLL + MLLT10MLL + PICALMMLLT10 + PICALMNCOA1 + PAX3NIN + PDGFRBNPM1 + RARANRG1 + ODZ4NTRK1 + TFGNUMA1 + RARANUP98 + PHF23PAX5 + ZNF521PBX1 + TCF3RET + TRIM27ROS1 + SLC34A2PML + RARAPRKAR1A + RARAPRKAR1A + RETRUNX1 + RUNX1T1RUNX1 + SH3D19	Cytoscape Web will replace the contents your graph	PPI Properties: Click on nodes or edges
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Statistics and Network structure information

Statistic of PPI Value(s) The number of interactors (fusion and proteins) 336 The number (and %) of the onco-proteins 107 (31.85 %) The number (and %) of the tumor suppressors 42 (12.50 %) Total number of binary PPIs (saturation %) 2334 (4.15 %) The number (and %) of affected PPIs 341 (14.61 %) The number of possible different fusions 73 PPI diameter 4 PPI radius 2 The average degree of PPI 13.143 Assortativity coefficient -0.2789 The network average Clustering coefficient 0.385 The number (and %) of a zero Clustering coefficients 33 (9.82 %) The number (and %) of a zero Betweenness Centrality 42 (12.50 %)

ACTIVE INTERACTORS

List of the fusions
PPI for parental proteins: NF2,CTBP1	All fusions
Proteins found in more fusions	CTBP1 (see 2 fusions); TSN (see 1 fusions); EHMT2 (see 1 fusions); PRPF19 (see 2 fusions); DCAF1 (see 1 fusions); FOXP1 (see 3 fusions); BCL6 (see 2 fusions); SLC9A3R1 (see 2 fusions); RCOR1 (see 2 fusions); UBA3 (see 1 fusions); CHMP1A (see 2 fusions); KSR1 (see 1 fusions); IKZF1 (see 1 fusions); PRDX1 (see 1 fusions); APC (see 1 fusions); AMOTL2 (see 1 fusions); HDAC5 (see 1 fusions); EP300 (see 1 fusions); RPA1 (see 1 fusions); CUL4A (see 4 fusions); HDAC4 (see 1 fusions); RBBP8 (see 1 fusions); KCNIP3 (see 2 fusions); OFD1 (see 5 fusions); NF2 (see 1 fusions); NF2/CPNE3 (see 2 fusions); RNF111 (see 1 fusions); BAG3 (see 4 fusions); EZR (see 2 fusions); KMT2A (see 14 fusions); RPL3/RPL13A (see 1 fusions); KDM1A (see 3 fusions); CHD3 (see 1 fusions); PLCB1 (see 1 fusions); LUC7L3 (see 1 fusions); ECHS1 (see 1 fusions); DDB1 (see 4 fusions); SLC25A11 (see 1 fusions); GAPDH (see 5 fusions); TUBG1 (see 1 fusions); TERF2IP (see 1 fusions); S100A8 (see 3 fusions); CREBBP/MECOM (see 1 fusions); CTNNA1 (see 4 fusions); XRCC4 (see 1 fusions); MAPK9 (see 3 fusions); CTBP2 (see 2 fusions); PIAS2 (see 2 fusions); RUNX1 (see 2 fusions); KAT2B (see 1 fusions); HTT (see 1 fusions); CTH (see 3 fusions); PARP1 (see 1 fusions); FOXP2 (see 2 fusions); TP53 (see 3 fusions); CRY2 (see 3 fusions); GMDS (see 1 fusions); SERBP1 (see 1 fusions); BCOR (see 1 fusions); SP1 (see 1 fusions); CREBBP (see 6 fusions); CD2AP (see 1 fusions); MVP (see 2 fusions); LNX1 (see 1 fusions); SEC23B (see 2 fusions); SSNA1 (see 2 fusions); EGFR (see 2 fusions); EHMT1 (see 3 fusions); TSG101 (see 2 fusions); NTRK1/TPR (see 1 fusions); TBL1X (see 2 fusions); SMAD3 (see 3 fusions);

List of active interactors

#	Name	Type	Number of PPI (degree)	Clustering Coefficient	Betweenness Centrality	Domains (Pfam, InterPro, SMART): description
1	NF2	parental protein	193	0.033	35849.385	ERM (PF00769, IPR011259): Ezrin/radixin/moesin family FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain FERM_M (PF00373, IPR019748): FERM central domain FERM_N (PF09379, IPR018979): FERM N-terminal domain
2	CTBP1	parental protein	148	0.058	27116.399	2-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Cellsynth_D (PF03500, IPR022798): Cellulose synthase subunit D
3	ACTL6B	interactor	2	1.000	0	Actin (PF00022, IPR004000, SM00268): Actin
4	ADSS	interactor	3	1.000	0	Adenylsucc_synt (PF00709, IPR001114, SM00788): Adenylosuccinate synthetase
5	AFG3L2	interactor	6	0.467	7.231	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) FtsH_ext (PF06480, IPR011546): FtsH Extracellular Peptidase_M41 (PF01434, IPR000642): Peptidase family M41 TniB (PF05621, IPR008868): Bacterial TniB protein FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
6	AGAP2	oncoprotein	1	0	0	ArfGap (PF01412, IPR001164, SM00105): Putative GTPase activating protein for Arf PH (PF00169, IPR001849, SM00233): PH domain Ras (PF00071, IPR001806, SM00173): Ras family Med3 (PF11593, IPR020998): Mediator complex subunit 3 fungal Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
7	AKAP8L	interactor	6	0.600	4.508	AKAP95 (PF04988, IPR007071): A-kinase anchoring protein 95 (AKAP95) DUF3464 (PF11947, IPR021855): Protein of unknown function (DUF3464)
8	AKT1	oncoprotein	22	0.305	467.037	PH (PF00169, IPR001849, SM00233): PH domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
9	AMOT	oncoprotein	15	0.319	144.364	FAP (PF07174, IPR010801): Fibronectin-attachment protein (FAP) Gastrin (PF00918, IPR001651, SM00029): Gastrin/cholecystokinin family DUF2162 (PF09930, IPR017199): Predicted transporter (DUF2162) Angiomotin_C (PF12240, IPR024646): Angiomotin C terminal SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
10	AMOTL1	interactor	8	0.571	11.546	NPV_P10 (PF05531, IPR008702): Nucleopolyhedrovirus P10 protein Presenilin (PF01080, IPR001108): Presenilin Angiomotin_C (PF12240, IPR024646): Angiomotin C terminal DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200) CCDC-167 (PF15188, IPR028194): Coiled-coil domain-containing protein 167 APC_N_CC (PF16689, IPR032038): Coiled-coil N-terminus of APC, dimerisation domain
11	AMOTL2	protein found in more fusions	8	0.571	27.426	HOOK (PF05622, IPR008636): HOOK protein SlyX (PF04102, IPR007236): SlyX Angiomotin_C (PF12240, IPR024646): Angiomotin C terminal Rootletin (PF15035): Ciliary rootlet component, centrosome cohesion
12	AMPD2	interactor	3	1.000	0	A_deaminase (PF00962, IPR001365): Adenosine/AMP deaminase
13	APC	suppressor	14	0.154	216.173	APC_15aa (PF05972, IPR009240): APC 15 residue motif APC_basic (PF05956, IPR009234): APC basic domain APC_r (PF05923): APC repeat Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat DUF972 (PF06156, IPR010377): Protein of unknown function (DUF972) EB1_binding (PF05937, IPR009232): EB-1 Binding Domain FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid) SAMP (PF05924, IPR009224): SAMP Motif Suppressor_APC (PF11414, IPR026831): Adenomatous polyposis coli tumour suppressor protein AIF_C (PF14721, IPR029324): Apoptosis-inducing factor, mitochondrion-associated, C-term SAS4 (PF15460, IPR029184): Something about silencing, SAS, complex subunit 4 Arm_APC_u3 (PF16629): Armadillo-associated region on APC APC_u5 (PF16630): Unstructured region on APC between 1st and 2nd catenin-bdg motifs APC_u9 (PF16633): Unstructured region on APC between 1st two creatine-rich regions APC_u13 (PF16634): Unstructured region on APC between APC_crr and SAMP APC_u14 (PF16635): Unstructured region on APC between SAMP and APC_crr APC_u15 (PF16636): Unstructured region on APC between APC_crr regions 5 and 6 APC_N_CC (PF16689, IPR032038): Coiled-coil N-terminus of APC, dimerisation domain
14	ARNT2	interactor	3	0.667	1.542	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold PAP2 (PF01569, IPR000326, SM00014): PAP2 superfamily
15	ATAD3A	interactor	5	0.500	9.267	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) DUF3523 (PF12037, IPR021911): Domain of unknown function (DUF3523)
16	ATAD3B	interactor	4	0.500	3.188	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) TsaE (PF02367, IPR003442): Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF3523 (PF12037, IPR021911): Domain of unknown function (DUF3523)
17	ATIC	oncoprotein	6	0.400	104.644	AICARFT_IMPCHas (PF01808, IPR002695, SM00798): AICARFT/IMPCHase bienzyme MGS (PF02142, IPR011607, SM00851): MGS-like domain
18	ATP6V1H	interactor	2	0	1.583	V-ATPase_H_N (PF03224, IPR004908): V-ATPase subunit H V-ATPase_H_C (PF11698, IPR011987): V-ATPase subunit H
19	ATXN1L	interactor	7	0.267	130.746	AXH (PF08517, IPR013723, SM00536): Ataxin-1 and HBP1 module (AXH)
20	BAG3	oncoprotein	28	0.071	1060.610	BAG (PF02179, IPR003103, SM00264): BAG domain WW (PF00397, IPR001202, SM00456): WW domain
21	BCAS3	oncoprotein	9	0.250	60.232	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat BCAS3 (PF12490, IPR022175): Breast carcinoma amplified sequence 3
22	BCL3	oncoprotein	11	0.509	17.095	Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies)
23	BCL6	oncoprotein	18	0.390	118.322	BTB (PF00651, IPR013069, SM00225): BTB/POZ domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding DZR (PF12773, IPR025874): Double zinc ribbon zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2HE (PF16278, IPR032566): C2HE / C2H2 / C2HC zinc-binding finger
24	BCOR	oncoprotein	10	0.583	11.783	Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) BCOR (PF15808, IPR031628): BCL-6 co-repressor, non-ankyrin-repeat region PUFD (PF16553, IPR032365): BCORL-PCGF1-binding domain
25	BCORL1	suppressor	3	1.000	0	Herpes_DNAp_acc (PF04929, IPR007013): Herpes DNA replication accessory factor Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_4 (PF13637): Ankyrin repeats (many copies) BCOR (PF15808, IPR031628): BCL-6 co-repressor, non-ankyrin-repeat region PUFD (PF16553, IPR032365): BCORL-PCGF1-binding domain
26	BRCA1	suppressor	42	0.221	766.928	BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT
27	C15orf39	interactor	2	1.000	0	Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein
28	C1orf35	interactor	1	0	0	Protamine_P1 (PF00260, IPR000221): Protamine P1 SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal MMtag (PF10159, IPR019315): Kinase phosphorylation protein
29	CALML5	interactor	2	0	17.482	EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
30	CAPRIN1	interactor	5	0.600	2.303	DUF1140 (PF06600, IPR009520): Protein of unknown function (DUF1140) Caprin-1_C (PF12287, IPR022070): Cytoplasmic activation/proliferation-associated protein-1 C term
31	CARM1	oncoprotein	13	0.526	65.899	K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain PRMT5 (PF05185, IPR025799): PRMT5 arginine-N-methyltransferase CBP_GIL (PF10995, IPR017745): GGDEF I-site like or GIL domain CARM1 (PF11531, IPR020989): Coactivator-associated arginine methyltransferase 1 N terminal
32	CBR4	interactor	2	0	2.693	adh_short_C2 (PF13561): Enoyl-(Acyl carrier protein) reductase
33	CBS	interactor	8	0.238	137.311	CBS (PF00571, IPR000644, SM00116): CBS domain DUF1414 (PF07208, IPR009857): Protein of unknown function (DUF1414) PALP (PF00291, IPR001926): Pyridoxal-phosphate dependent enzyme
34	CBX4	oncoprotein	13	0.197	116.731	Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein SelP_N (PF04592, IPR007671): Selenoprotein P, N terminal region CBX7_C (PF17218): CBX family C-terminal motif
35	CCNB1IP1	oncoprotein	3	1.000	0	MAD (PF05557, IPR008672): Mitotic checkpoint protein Paramyx_P_V_C (PF03210, IPR004897): Paramyxovirus P/V phosphoprotein C-terminal zf-RING_5 (PF14634, IPR001841): zinc-RING finger domain
36	CCNL2	interactor	5	0.400	12.294	Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
37	CD2AP	protein found in more fusions	7	0.400	21.876	SH3_1 (PF00018, IPR001452, SM00326): SH3 domain SH3_9 (PF14604, IPR001452): Variant SH3 domain betaPIX_CC (PF16523, IPR032409): betaPIX coiled coil
38	CD44	suppressor	7	0.238	34.078	VP4_2 (PF08935, IPR015031): Viral protein VP4 subunit Xlink (PF00193, IPR000538, SM00445): Extracellular link domain S36_mt (PF10937, IPR020373): Ribosomal protein S36, mitochondrial
39	CDC23	interactor	8	0.190	63.579	ANAPC8 (PF04049, IPR007192): Anaphase promoting complex subunit 8 / Cdc23 DUF772 (PF05598, IPR008490): Transposase domain (DUF772) Menin (PF05053, IPR007747): Menin TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat TPR_6 (PF13174, IPR019734): Tetratricopeptide repeat TPR_7 (PF13176, IPR019734): Tetratricopeptide repeat TPR_11 (PF13414, IPR011990): TPR repeat TPR_14 (PF13428): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat
40	CDK1	oncoprotein	18	0.265	285.929	Pkinase (PF00069, IPR000719): Protein kinase domain
41	CDK5	oncoprotein	8	0.238	71.171	Pkinase (PF00069, IPR000719): Protein kinase domain
42	CDYL	interactor	8	0.643	13.439	Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain ECH_1 (PF00378, IPR001753): Enoyl-CoA hydratase/isomerase ECH_2 (PF16113, IPR032259): Enoyl-CoA hydratase/isomerase
43	CEP68	interactor	1	0	0	Spectrin (PF00435, IPR002017): Spectrin repeat
44	CHD3	oncoprotein	24	0.253	486.411	CHDCT2 (PF08074, IPR012957): CHDCT2 (NUC038) domain CHDNT (PF08073, IPR012958): CHDNT (NUC034) domain Chromo (PF00385, IPR023780, SM00298): Chromo (CHRromatin Organisation MOdifier) domain DUF1086 (PF06461, IPR009462, SM01146): Domain of Unknown Function (DUF1086) DUF1087 (PF06465, IPR009463, SM01147): Domain of Unknown Function (DUF1087) DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator FYDLN_acid (PF09538, IPR012644): Protein of unknown function (FYDLN_acid) PHD (PF00628, IPR019787, SM00249): PHD-finger Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein SMN (PF06003, IPR010304): Survival motor neuron protein (SMN) SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain DUF2956 (PF11169, IPR021339): Protein of unknown function (DUF2956) FAM176 (PF14851): FAM176 family
45	CHMP1A	protein found in more fusions	7	0.467	29.362	Snf7 (PF03357, IPR005024): Snf7
46	CHMP4B	interactor	12	0.309	132.404	Snf7 (PF03357, IPR005024): Snf7
47	CKAP5	interactor	8	0.286	35.576	HEAT (PF02985, IPR000357): HEAT repeat PAS_6 (PF08348, IPR013559): YheO-like PAS domain UME (PF08064, IPR012993, SM00802): UME (NUC010) domain CLASP_N (PF12348, IPR024395): CLASP N terminal Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
48	CLCC1	interactor	1	0	0	MCLC (PF05934, IPR009231): Mid-1-related chloride channel (MCLC)
49	CPNE3	protein found in more fusions	5	0.300	32.782	C2 (PF00168, IPR000008, SM00239): C2 domain Copine (PF07002, IPR010734): Copine
50	CPSF6	interactor	3	0	9.012	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term PRIMA1 (PF16101): Proline-rich membrane anchor 1
51	CREBBP	suppressor	40	0.265	775.628	Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain MAS20 (PF02064, IPR002056): MAS20 protein import receptor TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26 HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729) DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834)
52	CRY2	protein found in more fusions	12	0.200	128.337	DNA_photolyase (PF00875, IPR006050): DNA photolyase FAD_binding_7 (PF03441, IPR005101): FAD binding domain of DNA photolyase
53	CTBP2	protein found in more fusions	49	0.094	1952.891	2-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
54	CTH	protein found in more fusions	8	0.286	97.212	Cys_Met_Meta_PP (PF01053, IPR000277): Cys/Met metabolism PLP-dependent enzyme
55	CTNNA1	oncoprotein	10	0.361	57.892	Vinculin (PF01044, IPR006077): Vinculin family
56	CTNNB1	oncoprotein	42	0.182	1050.981	Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361) HEAT_EZ (PF13513): HEAT-like repeat
57	CUL4A	protein found in more fusions	28	0.208	302.032	Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
58	DARS	interactor	12	0.348	63.485	tRNA-synt_2 (PF00152, IPR004364): tRNA synthetases class II (D, K and N) tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
59	DBN1	oncoprotein	10	0.333	48.071	Pinin_SDK_memA (PF04696, IPR006786): pinin/SDK/memA/ protein conserved region Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein CAF-1_p150 (PF11600): Chromatin assembly factor 1 complex p150 subunit, N-terminal MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
60	DBT	interactor	3	0.333	16.325	2-oxoacid_dh (PF00198, IPR001078): 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl (PF00364, IPR000089): Biotin-requiring enzyme E3_binding (PF02817, IPR004167): e3 binding domain HlyD_D23 (PF16576, IPR032317): Barrel-sandwich domain of CusB or HlyD membrane-fusion
61	DCAF1	protein found in more fusions	18	0.294	270.559	DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913) LisH (PF08513, IPR013720, SM00667): LisH ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated
62	DDB1	protein found in more fusions	28	0.265	418.999	CPSF_A (PF03178, IPR004871): CPSF A subunit region MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term
63	DECR1	interactor	7	0.429	112.187	adh_short_C2 (PF13561): Enoyl-(Acyl carrier protein) reductase
64	DGCR6	interactor	6	0.200	112.974	DGCR6 (PF07324, IPR010849): DiGeorge syndrome critical region 6 (DGCR6) protein
65	DHX15	interactor	14	0.374	56.456	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2) Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain AAA_29 (PF13555): P-loop containing region of AAA domain
66	DHX30	interactor	6	0.600	9.223	Bombolitin (PF08096, IPR012534): Bombolitin family DEAD (PF00270, IPR011545): DEAD/DEAH box helicase dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif Dicer_dimer (PF03368, IPR005034): Dicer dimerisation domain OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2) Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
67	DLAT	interactor	5	0.400	15.792	2-oxoacid_dh (PF00198, IPR001078): 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl (PF00364, IPR000089): Biotin-requiring enzyme E3_binding (PF02817, IPR004167): e3 binding domain Rib_recp_KP_reg (PF05104, IPR007794): Ribosome receptor lysine/proline rich region Stm1_N (PF09598, IPR019084): Stm1 NICE-1 (PF15845, IPR031698): Cysteine-rich C-terminal 1 family
68	DMRTB1	interactor	3	0.333	66.780	DM (PF00751, IPR001275, SM00301): DM DNA binding domain Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator VIR_N (PF15912, IPR031801): Virilizer, N-terminal
69	DNAJA1	interactor	17	0.301	154.684	DnaJ (PF00226, IPR001623, SM00271): DnaJ domain DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
70	DNAJA2	interactor	15	0.352	80.844	DnaJ (PF00226, IPR001623, SM00271): DnaJ domain DnaJ_C (PF01556, IPR002939): DnaJ C terminal domain
71	DNMT1	suppressor	19	0.510	64.358	BAH (PF01426, IPR001025, SM00439): BAH domain DMAP_binding (PF06464, IPR010506, SM01137): DMAP1-binding Domain DNA_methylase (PF00145, IPR001525): C-5 cytosine-specific DNA methylase zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain DNMT1-RFD (PF12047, IPR022702): Cytosine specific DNA methyltransferase replication foci domain
72	DNPEP	interactor	4	0	139.106	Peptidase_M18 (PF02127, IPR001948): Aminopeptidase I zinc metalloprotease (M18)
73	DSC1	interactor	4	0.500	22.798	Cadherin_C (PF01049, IPR000233): Cadherin cytoplasmic region Cadherin_pro (PF08758, IPR014868, SM01055): Cadherin prodomain like UPF0114 (PF03350, IPR005134): Uncharacterized protein family, UPF0114 Cadherin (PF00028, IPR002126, SM00112): Cadherin domain
74	DUT	interactor	6	0.400	58.475	dUTPase (PF00692, IPR008180): dUTPase
75	DYNLL1	interactor	13	0.212	156.506	Dynein_light (PF01221, IPR001372): Dynein light chain type 1
76	DYRK1A	oncoprotein	16	0.267	201.153	DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755) Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region Pkinase (PF00069, IPR000719): Protein kinase domain FAM199X (PF15814, IPR029672): Protein family FAM199X
77	E2F7	interactor	2	0	0	E2F_TDP (PF02319, IPR003316): E2F/DP family winged-helix DNA-binding domain Pro_3_hydrox_C (PF05373, IPR008035): L-proline 3-hydroxylase, C-terminal
78	ECHS1	protein found in more fusions	8	0.286	159.048	ECH_1 (PF00378, IPR001753): Enoyl-CoA hydratase/isomerase
79	ECT2	suppressor	11	0.164	190.370	BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain PTCB-BRCT (PF12738, IPR001357): twin BRCT domain PGBA_C (PF15437, IPR032737): Plasminogen-binding protein pgbA C-terminal
80	EGFR	oncoprotein	53	0.097	2403.774	Furin-like (PF00757, IPR006211): Furin-like cysteine rich region Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase Recep_L_domain (PF01030, IPR000494): Receptor L domain GAPT (PF11770, IPR021082): GRB2-binding adapter (GAPT) GF_recep_IV (PF14843, IPR032778): Growth factor receptor domain IV
81	EHMT1	oncoprotein	12	0.673	12.743	Pre-SET (PF05033, IPR007728): Pre-SET motif Ribosomal_L32p (PF01783, IPR002677): Ribosomal L32p protein family SET (PF00856, IPR001214, SM00317): SET domain XRCC4 (PF06632, IPR010585): DNA double-strand break repair and V(D)J recombination protein XRCC4 Zip (PF02535, IPR003689): ZIP Zinc transporter Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) DUF4551 (PF15087, IPR027878): Protein of unknown function (DUF4551)
82	EHMT2	protein found in more fusions	25	0.254	472.279	CDC45 (PF02724, IPR003874): CDC45-like protein Pre-SET (PF05033, IPR007728): Pre-SET motif Ribosomal_L32p (PF01783, IPR002677): Ribosomal L32p protein family SET (PF00856, IPR001214, SM00317): SET domain SMN (PF06003, IPR010304): Survival motor neuron protein (SMN) Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) CSRNP_N (PF16019, IPR031972): Cysteine/serine-rich nuclear protein N-terminus
83	EIF2S3	interactor	7	0.476	19.316	eIF2_C (PF09173, IPR015256): Initiation factor eIF2 gamma, C terminal GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2
84	EIF3J	interactor	4	0.667	2.586	eIF3_subunit (PF08597, IPR013906): Translation initiation factor eIF3 subunit
85	EIF3M	interactor	4	0.500	3.881	Death (PF00531, IPR000488, SM00005): Death domain PCI (PF01399, IPR000717, SM00088): PCI domain
86	ELAVL1	oncoprotein	69	0.069	4756.270	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
87	EMD	interactor	18	0.265	249.350	LEM (PF03020, IPR003887, SM00540): LEM domain SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
88	EP300	oncoprotein	50	0.198	1264.792	Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
89	EPDR1	interactor	1	0	0	Ependymin (PF00811, IPR001299, SM00026): Ependymin
90	ERLIN2	interactor	5	0.400	9.160	Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family DUF4346 (PF14251, IPR025595): Domain of unknown function (DUF4346)
91	EZR	protein found in more fusions	17	0.283	210.373	DUF106 (PF01956, IPR002809): Integral membrane protein DUF106 ERM (PF00769, IPR011259): Ezrin/radixin/moesin family FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain FERM_M (PF00373, IPR019748): FERM central domain FERM_N (PF09379, IPR018979): FERM N-terminal domain
92	FARSA	interactor	4	0.333	15.201	tRNA-synt_2d (PF01409, IPR002319): tRNA synthetases class II core domain (F) MarR_2 (PF12802): MarR family
93	FBF1	interactor	5	0.600	8.844	DUF737 (PF05300, IPR007964): Protein of unknown function (DUF737) OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) Sacchrp_dh_NADP (PF03435, IPR005097): Saccharopine dehydrogenase NADP binding domain Spc24 (PF08286, IPR013252): Spc24 subunit of Ndc80 Atg14 (PF10186, IPR018791): Vacuolar sorting 38 and autophagy-related subunit 14 Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family YlqD (PF11068, IPR021297): YlqD protein KfrA_N (PF11740, IPR021104): Plasmid replication region DNA-binding N-term
94	FBXO11	oncoprotein	4	0.833	2.455	TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit zf-UBR (PF02207, IPR003126): Putative zinc finger in N-recognin (UBR box) F-box-like (PF12937, IPR001810): F-box-like Beta_helix (PF13229): Right handed beta helix region
95	FKBP1A	interactor	6	0.400	36.152	FKBP_C (PF00254, IPR001179): FKBP-type peptidyl-prolyl cis-trans isomerase Hemopexin (PF00045, IPR018487, SM00120): Hemopexin
96	FOXK1	interactor	8	0.607	50.120	Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator FHA (PF00498, IPR000253, SM00240): FHA domain Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
97	FOXP1	suppressor	14	0.218	262.688	Auxin_repressed (PF05564, IPR008406): Dormancy/auxin associated protein DOPA_dioxygen (PF08883, IPR014980): Dopa 4,5-dioxygenase family Forkhead (PF00250, IPR001766, SM00339): Forkhead domain DUF4298 (PF14131, IPR025384): Domain of unknown function (DUF4298) FOXP-CC (PF16159, IPR032354): FOXP coiled-coil domain
98	FOXP2	protein found in more fusions	5	0.500	28.967	Auxin_repressed (PF05564, IPR008406): Dormancy/auxin associated protein CDC45 (PF02724, IPR003874): CDC45-like protein Plasmodium_Vir (PF05795, IPR008780): Plasmodium vivax Vir protein Forkhead (PF00250, IPR001766, SM00339): Forkhead domain Draxin (PF15550, IPR029094): Draxin SPATA3 (PF15662, IPR026717): Spermatogenesis-associated protein 3 family FOXP-CC (PF16159, IPR032354): FOXP coiled-coil domain
99	FUNDC1	interactor	2	1.000	0	FUN14 (PF04930, IPR007014): FUN14 family
100	G3BP2	interactor	8	0.357	26.501	NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
101	GAPDH	oncoprotein	15	0.407	139.681	Gp_dh_C (PF02800, IPR020829): Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N (PF00044, IPR020828, SM00846): Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain OstA (PF03968, IPR005653): OstA-like protein
102	GEMIN2	interactor	3	0.667	3.654	SIP1 (PF04938): Survival motor neuron (SMN) interacting protein 1 (SIP1) Glyco_trans_4_4 (PF13579, IPR028098): Glycosyl transferase 4-like domain
103	GMDS	protein found in more fusions	6	0.200	122.505	GDP_Man_Dehyd (PF16363, IPR016040): GDP-mannose 4,6 dehydratase
104	GPD2	interactor	2	0	1.088	DAO (PF01266, IPR006076): FAD dependent oxidoreductase EF-hand_7 (PF13499, IPR011992): EF-hand domain pair DAO_C (PF16901, IPR031656): C-terminal domain of alpha-glycerophosphate oxidase
105	GPS1	interactor	5	0.600	3.781	RPN7 (PF10602, IPR019585): 26S proteasome subunit RPN7 PCI (PF01399, IPR000717, SM00088): PCI domain
106	GRN	oncoprotein	4	0.333	3.244	Granulin (PF00396, IPR000118, SM00277): Granulin Lustrin_cystein (PF14625, IPR028150): Lustrin, cysteine-rich repeated domain
107	GRPEL1	interactor	9	0.607	71.284	GrpE (PF01025, IPR000740): GrpE
108	GRSF1	interactor	6	0.467	7.285	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence VWA_N2 (PF16164, IPR032361): VWA N-terminal
109	GTF2B	interactor	8	0.429	43.384	Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain TFIIB (PF00382, IPR013150): Transcription factor TFIIB repeat TF_Zn_Ribbon (PF08271, IPR013137): TFIIB zinc-binding
110	GTPBP1	interactor	4	0.500	2.846	GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain
111	HDAC1	suppressor	68	0.152	4153.871	FSAP_sig_propep (PF03032, IPR004275): Frog skin active peptide family signal and propeptide Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
112	HDAC2	suppressor	54	0.187	1891.381	Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain NARP1 (PF12569, IPR021183): NMDA receptor-regulated protein 1
113	HDAC3	suppressor	34	0.216	354.528	Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain
114	HDAC4	oncoprotein	23	0.281	235.271	Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
115	HDAC5	protein found in more fusions	50	0.116	1824.885	Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain NOA36 (PF06524, IPR010531): NOA36 protein Activator_LAG-3 (PF11498, IPR021587): Transcriptional activator LAG-3 HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4
116	HDAC9	interactor	13	0.303	96.539	Hist_deacetyl (PF00850, IPR023801): Histone deacetylase domain SAE2 (PF08573, IPR013882): DNA repair protein endonuclease SAE2/CtIP C-terminus HDAC4_Gln (PF12203, IPR024643): Glutamine rich N terminal domain of histone deacetylase 4 CEP19 (PF14933, IPR029412): CEP19-like protein
117	HEMGN	interactor	3	0.667	2.363	BRF1 (PF07741, IPR011665): Brf1-like TBP-binding domain
118	HGS	interactor	16	0.200	360.068	FYVE (PF01363, IPR000306, SM00064): FYVE zinc finger UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif VHS (PF00790, IPR002014, SM00288): VHS domain EF-1_beta_acid (PF10587, IPR018940): Eukaryotic elongation factor 1 beta central acidic region Hrs_helical (PF12210, IPR024641): Hepatocyte growth factor-regulated tyrosine kinase substrate PIEZO (PF15917, IPR031805): Piezo
119	HIC1	suppressor	12	0.364	53.244	BTB (PF00651, IPR013069, SM00225): BTB/POZ domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger
120	HIC2	interactor	3	1.000	0	BTB (PF00651, IPR013069, SM00225): BTB/POZ domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain
121	HIST3H3	interactor	28	0.235	355.729	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
122	HOXB5	interactor	2	1.000	0	DUF739 (PF05339, IPR008003): Protein of unknown function (DUF739) Homeobox (PF00046, IPR001356, SM00389): Homeobox domain
123	HSD11B2	interactor	4	0.500	1.117	adh_short (PF00106, IPR002198): short chain dehydrogenase DUF1776 (PF08643, IPR013952): Fungal family of unknown function (DUF1776)
124	HSD17B4	interactor	3	0.667	1.088	adh_short (PF00106, IPR002198): short chain dehydrogenase MaoC_dehydratas (PF01575, IPR002539): MaoC like domain SCP2 (PF02036, IPR003033): SCP-2 sterol transfer family MaoC_dehydrat_N (PF13452): N-terminal half of MaoC dehydratase
125	HSPA4	interactor	37	0.212	826.835	Herpes_ICP4_N (PF03584, IPR005206): Herpesvirus ICP4-like protein N-terminal region HSP70 (PF00012, IPR013126): Hsp70 protein TP53IP5 (PF15331, IPR029290): Cellular tumour antigen p53-inducible 5
126	HSPA9	oncoprotein	23	0.257	531.520	HSP70 (PF00012, IPR013126): Hsp70 protein
127	HSPH1	oncoprotein	13	0.346	95.687	HSP70 (PF00012, IPR013126): Hsp70 protein SICA_alpha (PF12887, IPR024290): SICA extracellular alpha domain
128	HTT	protein found in more fusions	14	0.372	51.653	HEAT (PF02985, IPR000357): HEAT repeat SPX (PF03105, IPR004331): SPX domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit DUF3652 (PF12372, IPR024613): Huntingtin protein region Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats
129	HYI	interactor	2	0	8.079	AP_endonuc_2 (PF01261, IPR013022): Xylose isomerase-like TIM barrel
130	IGF2BP1	oncoprotein	8	0.286	22.663	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KH_1 (PF00013, IPR004088, SM00322): KH domain KH_4 (PF13083): KH domain MOEP19 (PF16005, IPR031952): KH-like RNA-binding domain
131	IKBIP	interactor	5	0.300	44.856	Fez1 (PF06818): Fez1 Occludin_ELL (PF07303, IPR010844): Occludin homology domain GAS (PF13851, IPR025593): Growth-arrest specific micro-tubule binding DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200) SesA (PF17107, IPR031352): N-terminal domain on NACHT_NTPase and P-loop NTPases
132	IKZF1	suppressor	19	0.340	181.393	Desulfoferrod_N (PF06397, IPR004462): Desulfoferrodoxin, N-terminal domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-met (PF12874): Zinc-finger of C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger
133	IKZF2	suppressor	8	0.714	1.745	ADK_lid (PF05191, IPR007862): Adenylate kinase, active site lid zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies) zf-met (PF12874): Zinc-finger of C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger
134	IKZF4	interactor	6	0.800	0.403	ADK_lid (PF05191, IPR007862): Adenylate kinase, active site lid PyrI_C (PF02748, IPR020542): Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-met (PF12874): Zinc-finger of C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain FancD2 (PF14631, IPR029448): Fanconi anaemia protein FancD2 nuclease
135	INA	interactor	2	1.000	0	Filament (PF00038, IPR001664): Intermediate filament protein Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region Atg14 (PF10186, IPR018791): Vacuolar sorting 38 and autophagy-related subunit 14
136	IRS4	interactor	11	0.400	50.522	CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator IRS (PF02174, IPR002404, SM00310): PTB domain (IRS-1 type) Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence PH_11 (PF15413): Pleckstrin homology domain
137	IST1	interactor	3	1.000	0	Ist1 (PF03398, IPR005061): Regulator of Vps4 activity in the MVB pathway
138	KAT2A	interactor	13	0.303	92.760	Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family PCAF_N (PF06466, IPR009464): PCAF (P300/CBP-associated factor) N-terminal domain Bromodomain (PF00439, IPR001487, SM00297): Bromodomain NICE-1 (PF15845, IPR031698): Cysteine-rich C-terminal 1 family
139	KAT2B	protein found in more fusions	27	0.302	284.208	Acetyltransf_1 (PF00583, IPR000182): Acetyltransferase (GNAT) family PCAF_N (PF06466, IPR009464): PCAF (P300/CBP-associated factor) N-terminal domain Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
140	KCNIP3	protein found in more fusions	4	1.000	0	SPARC_Ca_bdg (PF10591, IPR019577): Secreted protein acidic and rich in cysteine Ca binding region EF-hand_7 (PF13499, IPR011992): EF-hand domain pair EF-hand_8 (PF13833, IPR002048): EF-hand domain pair EF-hand_9 (PF14658): EF-hand domain
141	KDM1A	protein found in more fusions	32	0.239	1546.307	Amino_oxidase (PF01593, IPR002937): Flavin containing amine oxidoreductase CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain SWIRM (PF04433, IPR007526): SWIRM domain DUF4298 (PF14131, IPR025384): Domain of unknown function (DUF4298)
142	KLF12	interactor	2	1.000	0	zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Macoilin (PF09726, IPR019130): Transmembrane protein zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
143	KLF3	oncoprotein	4	0.667	0.846	DUF1071 (PF06378, IPR009425): Protein of unknown function (DUF1071) zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
144	KLF4	suppressor	7	0.762	1.075	zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
145	KLF8	interactor	7	0.571	69.576	zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type MAGE_N (PF12440, IPR021072): Melanoma associated antigen family N terminal zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
146	KMT2A	oncoprotein	15	0.473	39.553	AT_hook (PF02178, IPR017956, SM00384): AT hook motif DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) FYRC (PF05965, IPR003889, SM00542): F/Y rich C-terminus FYRN (PF05964, IPR003888, SM00541): F/Y-rich N-terminus Peptidase_S49_N (PF08496, IPR013703): Peptidase family S49 N-terminal PHD (PF00628, IPR019787, SM00249): PHD-finger Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 SET (PF00856, IPR001214, SM00317): SET domain zf-CXXC (PF02008, IPR002857): CXXC zinc finger domain SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain zf-HC5HC2H (PF13771): PHD-like zinc-binding domain DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834)
147	KPNA2	interactor	10	0.222	128.433	Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat IBB (PF01749, IPR002652): Importin beta binding domain Arm_3 (PF16186, IPR032413): Atypical Arm repeat
148	KSR1	oncoprotein	3	1.000	0	Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain) KSR1-SAM (PF13543, IPR025561): SAM like domain present in kinase suppressor RAS 1
149	LANCL2	interactor	6	0.200	33.712	Glyco_hydro_127 (PF07944, IPR012878): Beta-L-arabinofuranosidase, GH127 LANC_like (PF05147, IPR007822): Lanthionine synthetase C-like protein
150	LATS1	suppressor	10	0.422	77.642	Cas_Cas6 (PF01881, IPR010156): CRISPR associated protein Cas6 Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
151	LATS2	suppressor	15	0.330	154.711	Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
152	LCOR	interactor	6	0.333	39.352	DUF4553 (PF15090, IPR028104): Domain of unknown function (DUF4553)
153	LCOR	interactor	5	0.300	59.501	DUF4553 (PF15090, IPR028104): Domain of unknown function (DUF4553)
154	LCORL	interactor	1	0	0	Y_phosphatase2 (PF03162, IPR004861): Tyrosine phosphatase family DUF4553 (PF15090, IPR028104): Domain of unknown function (DUF4553)
155	LEMD2	interactor	2	1.000	0	LEM (PF03020, IPR003887, SM00540): LEM domain MSC (PF09402, IPR018996): Man1-Src1p-C-terminal domain
156	LIG3	interactor	13	0.615	43.902	DNA_ligase_A_C (PF04679, IPR012309): ATP dependent DNA ligase C terminal region DNA_ligase_A_M (PF01068, IPR012310): ATP dependent DNA ligase domain DNA_ligase_A_N (PF04675, IPR012308): DNA ligase N terminus Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein zf-PARP (PF00645, IPR001510): Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region HD_2 (PF12917, IPR027366): HD containing hydrolase-like enzyme Synaptonemal_3 (PF15191, IPR028145): Synaptonemal complex central element protein 3 LIG3_BRCT (PF16759, IPR031916): DNA ligase 3 BRCT domain
157	LIN7C	interactor	9	0.417	70.680	His_Phos_2 (PF00328, IPR000560): Histidine phosphatase superfamily (branch 2) L27 (PF02828, IPR014775, SM00569): L27 domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
158	LNX1	protein found in more fusions	7	0.200	102.524	PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) zf-rbx1 (PF12678, IPR024766): RING-H2 zinc finger domain zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger)
159	LPCAT1	interactor	4	0.167	29.856	JmjN (PF02375, IPR003349, SM00545): jmjN domain Acyltransferase (PF01553, IPR002123, SM00563): Acyltransferase EF-hand_6 (PF13405, IPR002048): EF-hand domain EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
160	LSM12	interactor	1	0	0	AD (PF09793, IPR019181, SM00995): Anticodon-binding domain
161	LUC7L3	protein found in more fusions	6	0.500	2.792	LUC7 (PF03194, IPR004882): LUC7 N_terminus Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP) DDRGK (PF09756, IPR019153, SM01128): DDRGK domain
162	MAPK9	suppressor	10	0.417	65.827	Pkinase (PF00069, IPR000719): Protein kinase domain Kinase-like (PF14531, IPR027916): Kinase-like
163	MARCH10	interactor	1	0	0	RINGv (PF12906, IPR011016, SM00744): RING-variant domain PARM (PF17061, IPR031431): PARM
164	MC1R	interactor	2	1.000	0	7tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family) 7tm_4 (PF13853): Olfactory receptor
165	MDM2	oncoprotein	34	0.189	861.175	Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region Presenilin (PF01080, IPR001108): Presenilin SWIB (PF02201, IPR003121, SM00151): SWIB/MDM2 domain zf-FPG_IleRS (PF06827, IPR010663): Zinc finger found in FPG and IleRS zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
166	MECOM	oncoprotein	12	0.470	33.036	SET (PF00856, IPR001214, SM00317): SET domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger
167	MED23	interactor	19	0.316	260.271	Med23 (PF11573, IPR021629): Mediator complex subunit 23
168	MED28	interactor	6	0.300	45.866	cwf21 (PF08312, IPR013170, SM01115): cwf21 domain Med28 (PF11594, IPR021640): Mediator complex subunit 28
169	MOV10	interactor	46	0.140	1080.789	AAA_12 (PF13087): AAA domain AAA_30 (PF13604): AAA domain
170	MPP2	interactor	3	0.333	21.910	L27 (PF02828, IPR014775, SM00569): L27 domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) SH3_2 (PF07653, IPR011511): Variant SH3 domain Guanylate_kin (PF00625, IPR008145, SM00072): Guanylate kinase
171	MPP6	interactor	3	0.333	5.281	L27 (PF02828, IPR014775, SM00569): L27 domain PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) SH3_2 (PF07653, IPR011511): Variant SH3 domain Guanylate_kin (PF00625, IPR008145, SM00072): Guanylate kinase
172	MTPAP	interactor	5	0.300	25.307	PAP_assoc (PF03828, IPR002058): Cid1 family poly A polymerase RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) tRNA_NucTransf2 (PF09249, IPR015329): tRNA nucleotidyltransferase, second domain
173	MTTP	interactor	1	0	0	Vitellogenin_N (PF01347, IPR001747, SM00638): Lipoprotein amino terminal region
174	MVP	oncoprotein	9	0.179	98.878	Vault (PF01505, IPR002499): Major Vault Protein repeat DUF2543 (PF10820, IPR020251): Protein of unknown function (DUF2543) MVP_shoulder (PF11978, IPR021870): Shoulder domain
175	NCOR2	oncoprotein	20	0.400	93.078	CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal MAS20 (PF02064, IPR002056): MAS20 protein import receptor OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain PSK (PF06404, IPR009438): Phytosulfokine precursor protein (PSK) SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) Gti1_Pac2 (PF09729, IPR018608): Gti1/Pac2 family PRCC (PF10253, IPR018800): Mitotic checkpoint regulator, MAD2B-interacting Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Spt20 (PF12090, IPR021950): Spt20 family DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) DUF4518 (PF15008, IPR026698): Domain of unknown function (DUF4518) GPS2_interact (PF15784, IPR031557): G-protein pathway suppressor 2-interacting domain DUF4820 (PF16091, IPR032150): Domain of unknown function (DUF4820)
176	NIT1	interactor	5	0.333	38.591	CN_hydrolase (PF00795, IPR003010): Carbon-nitrogen hydrolase
177	NME2	interactor	9	0.250	94.865	NDK (PF00334, IPR001564, SM00562): Nucleoside diphosphate kinase
178	NOL4	interactor	2	1.000	0	NOA36 (PF06524, IPR010531): NOA36 protein zf-H2C2 (PF09337, IPR015416): His(2)-Cys(2) zinc finger BEN (PF10523, IPR018379, SM01025): BEN domain
179	NOL4L	interactor	2	1.000	0	ECSCR (PF15820, IPR026247): Endothelial cell-specific chemotaxis regulator
180	NRIP1	oncoprotein	10	0.467	10.375	ALMT (PF11744, IPR020966): Aluminium activated malate transporter NRIP1_repr_1 (PF15687, IPR031405): Nuclear receptor-interacting protein 1 repression 1 NRIP1_repr_2 (PF15688, IPR031406): Nuclear receptor-interacting protein 1 repression 2 NRIP1_repr_3 (PF15689, IPR031407): Nuclear receptor-interacting protein 1 repression 3 NRIP1_repr_4 (PF15690, IPR031408): Nuclear receptor-interacting protein 1 repression 4
181	NTRK1	oncoprotein	137	0.053	14615.080	I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
182	NXF1	interactor	53	0.079	1796.880	NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain LRR_8 (PF13855, IPR001611): Leucine rich repeat
183	OFD1	protein found in more fusions	14	0.269	321.439	APG6 (PF04111, IPR007243): Autophagy protein Apg6 Exonuc_VII_L (PF02601, IPR020579): Exonuclease VII, large subunit GrpE (PF01025, IPR000740): GrpE NPV_P10 (PF05531, IPR008702): Nucleopolyhedrovirus P10 protein XhlA (PF10779, IPR019715): Haemolysin XhlA DUF3372 (PF11852, IPR024561): Domain of unknown function (DUF3372) LisH_2 (PF16045, IPR006594): LisH
184	OR4X1	interactor	1	0	0	7tm_4 (PF13853): Olfactory receptor
185	ORC4	interactor	6	0.333	19.960	AAA_16 (PF13191): AAA ATPase domain ORC4_C (PF14629, IPR032705): Origin recognition complex (ORC) subunit 4 C-terminus
186	PABPC4	interactor	18	0.399	104.232	ApbA_C (PF08546, IPR013752): Ketopantoate reductase PanE/ApbA C terminal RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain HHV-5_US34A (PF17087, IPR031384): Herpesvirus US34A protein family
187	PANX1	interactor	2	0	4.878	Innexin (PF00876, IPR000990): Innexin Pannexin_like (PF12534, IPR021040): Pannexin-like TM region of LRRC8
188	PARP1	suppressor	42	0.245	1076.009	BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain PADR1 (PF08063, IPR012982): PADR1 (NUC008) domain PARP (PF00644, IPR012317): Poly(ADP-ribose) polymerase catalytic domain PARP_reg (PF02877, IPR004102): Poly(ADP-ribose) polymerase, regulatory domain WGR (PF05406, IPR008893, SM00773): WGR domain zf-PARP (PF00645, IPR001510): Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region
189	PDCD6	oncoprotein	12	0.291	53.519	EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
190	PDCD6IP	interactor	16	0.248	152.518	BRO1 (PF03097, IPR004328, SM01041): BRO1-like domain MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c ALIX_LYPXL_bnd (PF13949, IPR025304): ALIX V-shaped domain binding to HIV
191	PDHX	interactor	5	0.400	16.838	2-oxoacid_dh (PF00198, IPR001078): 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl (PF00364, IPR000089): Biotin-requiring enzyme E3_binding (PF02817, IPR004167): e3 binding domain
192	PEF1	interactor	6	0.400	147.074	EF-hand_6 (PF13405, IPR002048): EF-hand domain EF-hand_7 (PF13499, IPR011992): EF-hand domain pair EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
193	PGAM5	interactor	6	0.067	40.776	His_Phos_1 (PF00300, IPR013078, SM00855): Histidine phosphatase superfamily (branch 1)
194	PHB	suppressor	15	0.324	179.959	Band_7 (PF01145, IPR001107, SM00244): SPFH domain / Band 7 family DUF4290 (PF14123, IPR025632): Domain of unknown function (DUF4290)
195	PIAS2	protein found in more fusions	8	0.476	42.263	SAP (PF02037, IPR003034, SM00513): SAP domain zf-MIZ (PF02891, IPR004181): MIZ/SP-RING zinc finger PINIT (PF14324, IPR023321): PINIT domain
196	PIP4K2C	interactor	3	0	2.693	PIP5K (PF01504, IPR002498): Phosphatidylinositol-4-phosphate 5-Kinase
197	PLCB1	oncoprotein	6	0.100	73.372	DUF1154 (PF06631, IPR009535): Protein of unknown function (DUF1154) DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913) EF-hand_like (PF09279, IPR015359): Phosphoinositide-specific phospholipase C, efhand-like PLC-beta_C (PF08703, IPR014815): PLC-beta C terminal PI-PLC-X (PF00388, IPR000909, SM00148): Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y (PF00387, IPR001711, SM00149): Phosphatidylinositol-specific phospholipase C, Y domain DUF3987 (PF13148, IPR025048): Protein of unknown function (DUF3987) zf-C2H2_assoc (PF16606): Unstructured conserved, between two C2H2-type zinc-fingers
198	PLK1	suppressor	20	0.237	888.099	Pkinase (PF00069, IPR000719): Protein kinase domain POLO_box (PF00659, IPR000959): POLO box duplicated region
199	PNKP	interactor	17	0.397	150.152	PNK3P (PF08645, IPR013954): Polynucleotide kinase 3 phosphatase AAA_33 (PF13671): AAA domain
200	PNN	suppressor	3	0.667	11.944	Aconitase_C (PF00694, IPR000573): Aconitase C-terminal domain Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein Pinin_SDK_memA (PF04696, IPR006786): pinin/SDK/memA/ protein conserved region Pinin_SDK_N (PF04697, IPR006787): pinin/SDK conserved region Trypan_PARP (PF05887, IPR008882): Procyclic acidic repetitive protein (PARP)
201	PPP1R8	interactor	4	0.333	61.190	FHA (PF00498, IPR000253, SM00240): FHA domain
202	PRDM2	suppressor	6	0.800	1.096	CDC45 (PF02724, IPR003874): CDC45-like protein SET (PF00856, IPR001214, SM00317): SET domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal FAM163 (PF15069, IPR029379): FAM163 family zf-C2HE (PF16278, IPR032566): C2HE / C2H2 / C2HC zinc-binding finger
203	PRDX1	oncoprotein	9	0.500	20.207	AhpC-TSA (PF00578, IPR000866): AhpC/TSA family 1-cysPrx_C (PF10417, IPR019479): C-terminal domain of 1-Cys peroxiredoxin
204	PREB	interactor	1	0	0	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
205	PRKAA1	suppressor	10	0.400	99.816	Pkinase (PF00069, IPR000719): Protein kinase domain AdenylateSensor (PF16579, IPR032270): Adenylate sensor of SNF1-like protein kinase
206	PRKAG2	interactor	3	0.333	17.173	CBS (PF00571, IPR000644, SM00116): CBS domain
207	PRKCA	interactor	16	0.257	294.225	C2 (PF00168, IPR000008, SM00239): C2 domain Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain C1_1 (PF00130, IPR002219, SM00109): Phorbol esters/diacylglycerol binding domain (C1 domain)
208	PRPF19	protein found in more fusions	12	0.491	18.908	Prp19 (PF08606, IPR013915): Prp19/Pso4-like WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat U-box (PF04564, IPR003613, SM00504): U-box domain ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
209	PRPF38B	interactor	1	0	0	PRP38 (PF03371, IPR005037): PRP38 family PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
210	PXN	oncoprotein	5	0.300	9.945	LIM (PF00412, IPR001781, SM00132): LIM domain Paxillin (PF03535): Paxillin family
211	PYCR2	interactor	5	0.100	51.747	ApbA (PF02558, IPR013332): Ketopantoate reductase PanE/ApbA F420_oxidored (PF03807, IPR028939): NADP oxidoreductase coenzyme F420-dependent P5CR_dimer (PF14748, IPR029036): Pyrroline-5-carboxylate reductase dimerisation
212	PYGO2	interactor	12	0.436	69.355	PHD (PF00628, IPR019787, SM00249): PHD-finger
213	RAI2	interactor	2	1.000	0	SOBP (PF15279, IPR026092): Sine oculis-binding protein
214	RARS	interactor	9	0.389	37.049	Arg_tRNA_synt_N (PF03485, IPR005148, SM01016): Arginyl tRNA synthetase N terminal domain DALR_1 (PF05746, IPR008909, SM00836): DALR anticodon binding domain DivIC (PF04977, IPR007060): Septum formation initiator tRNA-synt_1d (PF00750, IPR015945): tRNA synthetases class I (R) Mto2_bdg (PF12808, IPR024545): Micro-tubular organiser Mto1 C-term Mto2-binding region
215	RB1	suppressor	29	0.298	366.185	RB_A (PF01858, IPR002720): Retinoblastoma-associated protein A domain RB_B (PF01857, IPR002719): Retinoblastoma-associated protein B domain Rb_C (PF08934, IPR015030): Rb C-terminal domain DUF3452 (PF11934, IPR024599): Domain of unknown function (DUF3452) DUF4592 (PF15262, IPR028030): Domain of unknown function (DUF4592)
216	RBBP4	oncoprotein	29	0.293	726.031	eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Capsid_NCLDV (PF04451, IPR007542): Large eukaryotic DNA virus major capsid protein CAF1C_H4-bd (PF12265, IPR022052): Histone-binding protein RBBP4 or subunit C of CAF1 complex
217	RBBP5	oncoprotein	13	0.455	60.442	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat DUF2457 (PF10446, IPR018853): Protein of unknown function (DUF2457) ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
218	RBBP8	suppressor	10	0.417	19.543	ZapB (PF06005, IPR009252): Cell division protein ZapB Exonuc_VII_L (PF02601, IPR020579): Exonuclease VII, large subunit SAE2 (PF08573, IPR013882): DNA repair protein endonuclease SAE2/CtIP C-terminus CtIP_N (PF10482, IPR019518): Tumour-suppressor protein CtIP N-terminal domain DUF4446 (PF14584, IPR027981): Protein of unknown function (DUF4446)
219	RBL1	suppressor	14	0.352	83.509	RB_A (PF01858, IPR002720): Retinoblastoma-associated protein A domain RB_B (PF01857, IPR002719): Retinoblastoma-associated protein B domain Rb_C (PF08934, IPR015030): Rb C-terminal domain DUF3452 (PF11934, IPR024599): Domain of unknown function (DUF3452)
220	RCC2	oncoprotein	3	0.333	3.781	RCC1 (PF00415, IPR000408): Regulator of chromosome condensation (RCC1) repeat RCC1_2 (PF13540): Regulator of chromosome condensation (RCC1) repeat
221	RCOR1	protein found in more fusions	15	0.407	92.673	DivIC (PF04977, IPR007060): Septum formation initiator ELM2 (PF01448, IPR000949): ELM2 domain Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain FAM76 (PF16046, IPR032017): FAM76 protein
222	RCOR2	interactor	3	1.000	0	ELM2 (PF01448, IPR000949): ELM2 domain Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
223	RCOR3	interactor	6	0.667	1.881	ELM2 (PF01448, IPR000949): ELM2 domain Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain Myb_DNA-bind_7 (PF15963): Myb DNA-binding like
224	RFC1	interactor	13	0.474	156.263	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain GAGA_bind (PF06217, IPR010409): GAGA binding protein-like family Nexin_C (PF08628, IPR013937): Sorting nexin C terminal RFC1 (PF08519, IPR013725): Replication factor RFC1 C terminal domain DUF2316 (PF10078, IPR018757): Uncharacterized protein conserved in bacteria (DUF2316)
225	RFC3	interactor	8	0.607	7.743	CHB_HEX (PF03173, IPR004866, SM01081): Putative carbohydrate binding domain DNA_pol3_delta (PF06144, IPR010372): DNA polymerase III, delta subunit Rep_fac_C (PF08542, IPR013748): Replication factor C C-terminal domain DNA_pol3_delta2 (PF13177): DNA polymerase III, delta subunit
226	RIT1	interactor	1	0	0	Ras (PF00071, IPR001806, SM00173): Ras family
227	RNF111	suppressor	8	0.190	74.858	zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain Prok-RING_1 (PF14446): Prokaryotic RING finger family 1 RNF111_N (PF15303, IPR029306): E3 ubiquitin-protein ligase Arkadia N-terminus
228	RNF166	interactor	7	0.381	20.762	zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding zinc-ribbons_6 (PF07191, IPR010807): zinc-ribbons Rad50_zn_hook (PF04423, IPR007517): Rad50 zinc hook motif UIM (PF02809, IPR003903, SM00726): Ubiquitin interaction motif zinc_ribbon_2 (PF13240, IPR026870): zinc-ribbon domain zf-RING_UBOX (PF13445, IPR027370): RING-type zinc-finger zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain
229	RPA1	suppressor	44	0.235	591.636	Rep-A_N (PF04057, IPR007199): Replication factor-A protein 1, N-terminal domain Rep_fac-A_C (PF08646, IPR013955): Replication factor-A C terminal domain tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain REPA_OB_2 (PF16900, IPR031657): Replication protein A OB domain
230	RPA2	oncoprotein	44	0.196	811.369	RPA_C (PF08784, IPR014892): Replication protein A C terminal tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain RMI2 (PF16100, IPR032245): RecQ-mediated genome instability protein 2
231	RPL10	suppressor	36	0.306	588.106	Ribosomal_L16 (PF00252, IPR016180): Ribosomal protein L16p/L10e
232	RPL13	interactor	25	0.607	84.083	Ribosomal_L13e (PF01294, IPR001380): Ribosomal protein L13e
233	RPL13A	protein found in more fusions	21	0.795	17.158	Ribosomal_L13 (PF00572, IPR005822): Ribosomal protein L13
234	RPL14	interactor	23	0.692	69.945	KOW (PF00467, IPR005824, SM00739): KOW motif Ribosomal_L14e (PF01929, IPR002784): Ribosomal protein L14 UPF0688 (PF15772, IPR031530): UPF0688 family
235	RPL15	interactor	24	0.703	31.702	Ribosomal_L15e (PF00827, IPR000439): Ribosomal L15
236	RPL18	interactor	22	0.788	18.109	Ribosomal_L18 (PF17135): Ribosomal protein 60S L18 and 50S L18e
237	RPL18A	interactor	22	0.723	33.087	Ribosomal_L18A (PF01775, IPR023573): Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A
238	RPL3	protein found in more fusions	23	0.688	70.929	Ribosomal_L3 (PF00297, IPR000597): Ribosomal protein L3
239	RPL4	interactor	26	0.569	119.973	Ribosomal_L4 (PF00573, IPR002136): Ribosomal protein L4/L1 family Ribos_L4_asso_C (PF14374, IPR025755): 60S ribosomal protein L4 C-terminal domain
240	RPL8	interactor	21	0.748	48.631	Ribosomal_L2 (PF00181, IPR022666): Ribosomal Proteins L2, RNA binding domain Ribosomal_L2_C (PF03947, IPR022669): Ribosomal Proteins L2, C-terminal domain
241	RPS2	interactor	27	0.550	141.339	Ribosomal_S5 (PF00333, IPR013810): Ribosomal protein S5, N-terminal domain Ribosomal_S5_C (PF03719, IPR005324): Ribosomal protein S5, C-terminal domain
242	RPS3	interactor	31	0.460	332.980	KH_2 (PF07650, IPR004044): KH domain Ribosomal_S3_C (PF00189, IPR001351): Ribosomal protein S3, C-terminal domain
243	RPS3A	interactor	28	0.577	118.203	Ribosomal_S3Ae (PF01015, IPR001593): Ribosomal S3Ae family
244	RPS4X	interactor	25	0.607	296.256	KOW (PF00467, IPR005824, SM00739): KOW motif Ribosomal_S4e (PF00900, IPR013845): Ribosomal family S4e RS4NT (PF08071, IPR013843): RS4NT (NUC023) domain S4 (PF01479, IPR002942, SM00363): S4 domain 40S_S4_C (PF16121, IPR032277): 40S ribosomal protein S4 C-terminus
245	RPS5	interactor	24	0.623	54.374	Ribosomal_S7 (PF00177, IPR023798): Ribosomal protein S7p/S5e
246	RPS7	interactor	23	0.648	54.514	Ribosomal_S7e (PF01251, IPR000554): Ribosomal protein S7e
247	RREB1	oncoprotein	6	0.733	0.922	C1_4 (PF07975, IPR004595, SM01047): TFIIH C1-like domain DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180) DUF629 (PF04780, IPR006865): Protein of unknown function (DUF629) RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger FAM176 (PF14851): FAM176 family
248	RUNX1	suppressor	17	0.417	96.277	Runt (PF00853, IPR013524): Runt domain RunxI (PF08504, IPR013711): Runx inhibition domain DUF3037 (PF11236, IPR021398): Protein of unknown function (DUF3037)
249	S100A8	oncoprotein	7	0.267	38.128	S_100 (PF01023, IPR013787): S-100/ICaBP type calcium binding domain EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
250	S100A9	oncoprotein	11	0.400	26.030	S_100 (PF01023, IPR013787): S-100/ICaBP type calcium binding domain EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
251	SARS2	interactor	2	0	1.088	tRNA-synt_2b (PF00587, IPR002314): tRNA synthetase class II core domain (G, H, P, S and T) DUF2312 (PF10073, IPR018753): Uncharacterized protein conserved in bacteria (DUF2312) DUF4445 (PF14574, IPR027980): Domain of unknown function (DUF4445)
252	SATB1	oncoprotein	10	0.444	15.663	CUT (PF02376, IPR003350, SM01109): CUT domain Homeobox (PF00046, IPR001356, SM00389): Homeobox domain DUF3371 (PF11851, IPR021802): Domain of unknown function (DUF3371) ULD (PF16534, IPR032392): Ubiquitin-like oligomerisation domain of SATB CUTL (PF16557, IPR032355): CUT1-like DNA-binding domain of SATB SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
253	SCHIP1	interactor	2	0	0	SCHIP-1 (PF10148, IPR015649): Schwannomin-interacting protein 1
254	SDCBP	interactor	9	0.167	341.684	PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
255	SEC23B	protein found in more fusions	4	0.333	5.751	Gelsolin (PF00626, IPR007123): Gelsolin repeat Sec23_BS (PF08033, IPR012990): Sec23/Sec24 beta-sandwich domain Sec23_helical (PF04815, IPR006900): Sec23/Sec24 helical domain Sec23_trunk (PF04811, IPR006896): Sec23/Sec24 trunk domain zf-Sec23_Sec24 (PF04810, IPR006895): Sec23/Sec24 zinc finger
256	SERBP1	protein found in more fusions	11	0.422	53.962	HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family FXMRP1_C_core (PF12235, IPR022034): Fragile X-related 1 protein core C terminal FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1 IHABP4_N (PF16174, IPR032381): Intracellular hyaluronan-binding protein 4 N-terminal
257	SERPINB3	oncoprotein	1	0	0	Serpin (PF00079, IPR023796, SM00093): Serpin (serine protease inhibitor)
258	SERPINH1	interactor	8	0.464	113.141	Serpin (PF00079, IPR023796, SM00093): Serpin (serine protease inhibitor)
259	SF3B4	interactor	9	0.250	163.523	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
260	SFXN2	interactor	3	0.667	1.038	Mtc (PF03820, IPR004686): Tricarboxylate carrier
261	SGSM3	interactor	5	0.300	74.107	RUN (PF02759, IPR004012, SM00593): RUN domain RabGAP-TBC (PF00566, IPR000195, SM00164): Rab-GTPase-TBC domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
262	SH3GL1	oncoprotein	5	0.333	8.775	BAR (PF03114, IPR004148, SM00721): BAR domain PhnG (PF06754, IPR009609): Phosphonate metabolism protein PhnG SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
263	SLC25A1	interactor	6	0.400	62.394	Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
264	SLC25A11	protein found in more fusions	6	0.200	34.247	Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
265	SLC25A12	interactor	3	0.667	1.073	Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein EF-hand_1 (PF00036, IPR002048, SM00054): EF hand EF-hand_6 (PF13405, IPR002048): EF-hand domain EF-hand_7 (PF13499, IPR011992): EF-hand domain pair EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
266	SLC25A13	interactor	4	0.333	5.747	Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein EF-hand_6 (PF13405, IPR002048): EF-hand domain EF-hand_7 (PF13499, IPR011992): EF-hand domain pair EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
267	SLC25A22	interactor	3	0.333	1.657	Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein DUF4257 (PF14074, IPR025353): Protein of unknown function (DUF4257)
268	SLC25A3	interactor	11	0.309	95.090	Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
269	SLC25A5	interactor	16	0.575	53.502	Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
270	SLC25A6	interactor	7	0.143	121.497	Mito_carr (PF00153, IPR018108): Mitochondrial carrier protein
271	SLC33A1	interactor	1	0	0	Acatn (PF13000, IPR024371): Acetyl-coenzyme A transporter 1
272	SLC9A3R1	suppressor	11	0.311	120.318	EBP50_C (PF09007, IPR015098): EBP50, C-terminal PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
273	SMAD3	oncoprotein	34	0.184	1004.582	MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain
274	SMAD6	interactor	7	0.286	58.947	MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain
275	SMC1A	oncoprotein	14	0.385	94.674	SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
276	SMC3	oncoprotein	16	0.267	174.772	SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain
277	SNRPN	interactor	4	0.500	35.812	LSM (PF01423, IPR001163): LSM domain
278	SOBP	interactor	1	0	0	Mito_fiss_reg (PF05308, IPR007972): Mitochondrial fission regulator zf-FCS (PF06467, IPR010507): MYM-type Zinc finger with FCS sequence motif SOBP (PF15279, IPR026092): Sine oculis-binding protein
279	SOS1	oncoprotein	3	0.333	2.671	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4 PH (PF00169, IPR001849, SM00233): PH domain RasGEF (PF00617, IPR001895, SM00147): RasGEF domain RhoGEF (PF00621, IPR000219, SM00325): RhoGEF domain RasGEF_N (PF00618, IPR000651, SM00229): RasGEF N-terminal motif
280	SOX2	oncoprotein	30	0.148	769.760	HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box SOXp (PF12336, IPR022097): SOX transcription factor
281	SP1	protein found in more fusions	30	0.323	767.574	zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding Herpes_capsid (PF06112, IPR009299): Gammaherpesvirus capsid protein zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Miga (PF10265, IPR019392): Mitoguardin zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
282	SPEN	oncoprotein	7	0.571	7.098	ATP-synt_E (PF05680, IPR008386): ATP synthase E chain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rxt3 (PF08642, IPR013951): Histone deacetylation protein Rxt3 SPOC (PF07744, IPR012921): SPOC domain DUF4692 (PF15763, IPR031517): Domain of unknown function (DUF4692)
283	SPTBN1	suppressor	12	0.227	180.285	CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain COG2 (PF06148, IPR024602): COG (conserved oligomeric Golgi) complex component, COG2 DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) Spectrin (PF00435, IPR002017): Spectrin repeat PH_9 (PF15410): Pleckstrin homology domain
284	SRPRA	interactor	5	0.400	5.214	SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal SRP54 (PF00448, IPR000897, SM00962): SRP54-type protein, GTPase domain SRP54_N (PF02881, IPR013822, SM00963): SRP54-type protein, helical bundle domain
285	SRRM2	interactor	18	0.261	238.382	cwf21 (PF08312, IPR013170, SM01115): cwf21 domain DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) Pap_E4 (PF02711, IPR003861): E4 protein RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 CTD (PF12815, IPR024945, SM01104): Spt5 C-terminal nonapeptide repeat binding Spt4 DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614)
286	SSNA1	protein found in more fusions	4	0.333	24.474	APG6 (PF04111, IPR007243): Autophagy protein Apg6 Fzo_mitofusin (PF04799, IPR006884): fzo-like conserved region
287	SSRP1	interactor	9	0.556	24.415	Rtt106 (PF08512, IPR013719): Histone chaperone Rttp106-like SSrecog (PF03531, IPR024954): Structure-specific recognition protein (SSRP1) YABBY (PF04690, IPR006780): YABBY protein HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box DUF3987 (PF13148, IPR025048): Protein of unknown function (DUF3987) CAML (PF14963, IPR016719): Calcium signal-modulating cyclophilin ligand CCDC106 (PF15794, IPR031591): Coiled-coil domain-containing protein 106 Coilin_N (PF15862, IPR031722): Coilin N-terminus
288	SUPT16H	interactor	18	0.397	106.816	Nop14 (PF04147, IPR007276): Nop14-like family Peptidase_M24 (PF00557, IPR001714): Metallopeptidase family M24 Rtt106 (PF08512, IPR013719): Histone chaperone Rttp106-like SPT16 (PF08644, IPR013953): FACT complex subunit (SPT16/CDC68) Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal FACT-Spt16_Nlob (PF14826, IPR029148): FACT complex subunit SPT16 N-terminal lobe domain
289	TAF15	oncoprotein	8	0.393	44.320	API5 (PF05918, IPR008383): Apoptosis inhibitory protein 5 (API5) GRP (PF07172, IPR010800): Glycine rich protein family Presenilin (PF01080, IPR001108): Presenilin RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others
290	TBL1X	protein found in more fusions	9	0.536	17.159	K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain LisH (PF08513, IPR013720, SM00667): LisH WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat LCE6A (PF15858, IPR031716): Late cornified envelope protein 6A family
291	TBL2	suppressor	5	0.400	50.931	eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat FdsD (PF11390, IPR021074): NADH-dependant formate dehydrogenase delta subunit FdsD
292	TBP	interactor	19	0.438	362.612	TBP (PF00352, IPR000814): Transcription factor TFIID (or TATA-binding protein, TBP) EPL1 (PF10513, IPR019542): Enhancer of polycomb-like Med3 (PF11593, IPR020998): Mediator complex subunit 3 fungal
293	TCF4	suppressor	10	0.400	110.229	CDC45 (PF02724, IPR003874): CDC45-like protein HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
294	TCF7L2	suppressor	9	0.500	26.495	CTNNB1_binding (PF08347, IPR013558): N-terminal CTNNB1 binding HMG_box (PF00505, IPR009071, SM00398): HMG (high mobility group) box
295	TERF2	interactor	29	0.175	547.008	Aconitase_C (PF00694, IPR000573): Aconitase C-terminal domain TRF (PF08558, IPR013867): Telomere repeat binding factor (TRF) Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain TERF2_RBM (PF16772, IPR031902): Telomeric repeat-binding factor 2 Rap1-binding motif
296	TERF2IP	protein found in more fusions	11	0.311	94.254	BRF1 (PF07741, IPR011665): Brf1-like TBP-binding domain Histone_HNS (PF00816, IPR001801): H-NS histone family Myb_DNA-bind_2 (PF08914, IPR015010): Rap1 Myb domain Rap1_C (PF11626, IPR021661): TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF3391 (PF11871, IPR021812): Domain of unknown function (DUF3391) BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain
297	TFAP4	oncoprotein	16	0.367	195.271	DivIC (PF04977, IPR007060): Septum formation initiator HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain DUF2407 (PF10302, IPR019413): DUF2407 ubiquitin-like domain
298	TFCP2	interactor	9	0.194	156.443	CP2 (PF04516, IPR007604): CP2 transcription factor DUF2967 (PF11179, IPR021349): Protein of unknown function (DUF2967)
299	TGIF1	oncoprotein	5	0.400	8.030	Homeobox_KN (PF05920, IPR008422): Homeobox KN domain LRS4 (PF10422, IPR018479): Monopolin complex subunit LRS4
300	TGM3	suppressor	2	0	1.088	Transglut_C (PF00927, IPR008958): Transglutaminase family, C-terminal ig like domain Transglut_N (PF00868, IPR001102): Transglutaminase family Transglut_core (PF01841, IPR002931, SM00460): Transglutaminase-like superfamily
301	THAP11	interactor	5	0.500	7.769	THAP (PF05485, IPR006612, SM00980): THAP domain DUF2722 (PF10846, IPR021216): Protein of unknown function (DUF2722) MRP-S31 (PF15433, IPR026299): Mitochondrial 28S ribosomal protein S31 FAM76 (PF16046, IPR032017): FAM76 protein
302	TMPO	interactor	13	0.282	110.172	LEM (PF03020, IPR003887, SM00540): LEM domain Thymopoietin (PF08198, IPR013146): Thymopoietin protein LAP2alpha (PF11560, IPR021623): Lamina-associated polypeptide 2 alpha
303	TOP1	oncoprotein	16	0.308	187.234	DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764) Topoisom_I (PF01028, IPR013500): Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N (PF02919, IPR008336): Eukaryotic DNA topoisomerase I, DNA binding fragment MCM_bind (PF09739, IPR019140): Mini-chromosome maintenance replisome factor Sox_N (PF12444, IPR022151): Sox developmental protein N terminal Topo_C_assoc (PF14370, IPR025834): C-terminal topoisomerase domain DUF4614 (PF15391, IPR027884): Domain of unknown function (DUF4614) TonB_N (PF16031): TonB N-terminal region
304	TOR2A	interactor	1	0	0	Torsin (PF06309, IPR010448): Torsin AAA_22 (PF13401, IPR003593): AAA domain
305	TP53	suppressor	90	0.134	4758.981	DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region P53 (PF00870, IPR011615): P53 DNA-binding domain P53_tetramer (PF07710, IPR010991): P53 tetramerisation motif
306	TPR	oncoprotein	11	0.273	93.404	Baculo_PEP_C (PF04513, IPR007601): Baculovirus polyhedron envelope protein, PEP, C terminus ZapB (PF06005, IPR009252): Cell division protein ZapB Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family IncA (PF04156, IPR007285): IncA protein Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein Seryl_tRNA_N (PF02403, IPR015866): Seryl-tRNA synthetase N-terminal domain TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1 XhlA (PF10779, IPR019715): Haemolysin XhlA ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding Alanine_zipper (PF11839, IPR021793): Alanine-zipper, major outer membrane lipoprotein DUF3373 (PF11853, IPR021803): Protein of unknown function (DUF3373) DUF4107 (PF13389, IPR025180): Protein of unknown function (DUF4107) JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II CREPT (PF16566, IPR032337): Cell-cycle alteration and expression-elevated protein in tumour DUF5082 (PF16888, IPR031681): Domain of unknown function (DUF5082)
307	TRIM21	interactor	6	0.300	61.491	DUF313 (PF03754, IPR005508): Domain of unknown function (DUF313) SPRY (PF00622, IPR003877, SM00449): SPRY domain zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger PRY (PF13765, IPR006574, SM00589): SPRY-associated domain Prok-RING_1 (PF14446): Prokaryotic RING finger family 1 zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
308	TRMT61B	interactor	1	0	0	GCD14 (PF08704, IPR014816): tRNA methyltransferase complex GCD14 subunit
309	TRPS1	oncoprotein	4	0.500	49.805	Rubredoxin (PF00301, IPR024935): Rubredoxin zf-BED (PF02892, IPR003656, SM00614): BED zinc finger zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type GATA (PF00320, IPR000679, SM00401): GATA zinc finger zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain zf-C2H2_7 (PF15269): Zinc-finger
310	TSG101	suppressor	18	0.243	296.746	APG6 (PF04111, IPR007243): Autophagy protein Apg6 Laminin_II (PF06009, IPR010307): Laminin Domain II UEV (PF05743, IPR008883): UEV domain Vps23_core (PF09454, IPR017916): Vps23 core domain
311	TSHZ3	interactor	3	1.000	0	LMP (PF04778, IPR006864): LMP repeated region zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Homeobox (PF00046, IPR001356, SM00389): Homeobox domain zf-C2H2_2 (PF12756, IPR015880): C2H2 type zinc-finger (2 copies) zf-met (PF12874): Zinc-finger of C2H2 type zf-C2HE (PF16278, IPR032566): C2HE / C2H2 / C2HC zinc-binding finger
312	TSN	protein found in more fusions	3	0	85.800	Translin (PF01997, IPR002848): Translin family
313	TUBA1C	interactor	19	0.222	133.107	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
314	TUBB4A	interactor	5	0.400	4.365	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
315	TUBG1	protein found in more fusions	28	0.262	684.210	Tubulin (PF00091, IPR003008, SM00864): Tubulin/FtsZ family, GTPase domain Tubulin_C (PF03953, IPR018316, SM00865): Tubulin C-terminal domain
316	UBA3	protein found in more fusions	4	0.667	9.181	E2_bind (PF08825, IPR014929): E2 binding domain ThiF (PF00899, IPR000594): ThiF family
317	UBE2I	interactor	50	0.142	1883.190	UQ_con (PF00179, IPR000608): Ubiquitin-conjugating enzyme
318	VTA1	interactor	5	0.500	10.165	Vta1 (PF04652): Vta1 like
319	WBP2	interactor	3	0.333	5.313	GRAM (PF02893, IPR004182, SM00568): GRAM domain Vps36_ESCRT-II (PF11605, IPR021648): Vacuolar protein sorting protein 36 Vps36
320	WDCP	interactor	2	1.000	0	DUF4613 (PF15390, IPR028041): Domain of unknown function (DUF4613)
321	WDR1	interactor	11	0.236	264.465	eIF2A (PF08662, IPR013979): Eukaryotic translation initiation factor eIF2A PQQ (PF01011, IPR002372, SM00564): PQQ enzyme repeat WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
322	WIZ	interactor	11	0.455	30.982	AnfO_nitrog (PF09582, IPR014287): Iron only nitrogenase protein AnfO (AnfO_nitrog) C1_2 (PF03107, IPR004146): C1 domain Zn-ribbon_8 (PF09723, IPR013429, SM00834): Zinc ribbon domain Enterotoxin_ST (PF02048, IPR001489): Heat-stable enterotoxin ST zf-C2H2_4 (PF13894): C2H2-type zinc finger
323	WWC1	interactor	9	0.389	20.736	APG6 (PF04111, IPR007243): Autophagy protein Apg6 bZIP_Maf (PF03131, IPR004826): bZIP Maf transcription factor C2 (PF00168, IPR000008, SM00239): C2 domain Sec2p (PF06428, IPR009449): GDP/GTP exchange factor Sec2p Spc7 (PF08317, IPR013253, SM00787): Spc7 kinetochore protein Spore_III_AB (PF09548, IPR014198): Stage III sporulation protein AB (spore_III_AB) TPR_MLP1_2 (PF07926, IPR012929): TPR/MLP1/MLP2-like protein WW (PF00397, IPR001202, SM00456): WW domain
324	XRCC1	interactor	11	0.527	69.880	BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain SPX (PF03105, IPR004331): SPX domain XRCC1_N (PF01834, IPR002706): XRCC1 N terminal domain BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain
325	XRCC4	protein found in more fusions	6	0.600	11.657	XRCC4 (PF06632, IPR010585): DNA double-strand break repair and V(D)J recombination protein XRCC4
326	XRCC5	suppressor	29	0.259	514.951	Ku (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain Ku_PK_bind (PF08785, IPR014893): Ku C terminal domain like
327	XRCC6	oncoprotein	35	0.221	877.423	Ku (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain SAP (PF02037, IPR003034, SM00513): SAP domain
328	YAP1	suppressor	20	0.211	367.240	Bindin (PF02084, IPR000775): Bindin WW (PF00397, IPR001202, SM00456): WW domain GspL_C (PF12693, IPR025691): GspL periplasmic domain FAM181 (PF15238, IPR029359): FAM181
329	ZBP1	interactor	4	0.667	1.021	z-alpha (PF02295, IPR000607, SM00550): Adenosine deaminase z-alpha domain RHIM (PF12721, IPR025735): RIP homotypic interaction motif
330	ZBTB10	interactor	3	0	28.099	BTB (PF00651, IPR013069, SM00225): BTB/POZ domain Ribosomal_L37ae (PF01780, IPR002674): Ribosomal L37ae protein family zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain
331	ZBTB18	suppressor	4	0.333	143.697	BTB (PF00651, IPR013069, SM00225): BTB/POZ domain zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger UBZ_FAAP20 (PF15750, IPR031490): Ubiquitin-binding zinc-finger zinc_ribbon_15 (PF17032, IPR031493): zinc-ribbon family
332	ZEB1	interactor	8	0.429	18.476	CDC27 (PF09507, IPR019038): DNA polymerase subunit Cdc27 zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding GET2 (PF08690, IPR028143): GET complex subunit GET2 Pox_Ag35 (PF03286, IPR004966): Pox virus Ag35 surface protein RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Homeobox (PF00046, IPR001356, SM00389): Homeobox domain zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain
333	ZEB2	oncoprotein	10	0.489	23.766	zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding Rep_fac-A_C (PF08646, IPR013955): Replication factor-A C terminal domain Rubredoxin (PF00301, IPR024935): Rubredoxin zf-AN1 (PF01428, IPR000058, SM00154): AN1-like Zinc finger zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type Homeobox (PF00046, IPR001356, SM00389): Homeobox domain zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding SpoIIIAH (PF12685, IPR024232): SpoIIIAH-like protein zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-CCHC_5 (PF14787): GAG-polyprotein viral zinc-finger
334	ZNF217	oncoprotein	9	0.694	10.001	zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type DUF2256 (PF10013, IPR017136): Uncharacterized protein conserved in bacteria (DUF2256) zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain HiaBD2 (PF15403, IPR029275): HiaBD2_N domain of Trimeric autotransporter adhesin (GIN)
335	ZNF219	interactor	5	0.900	2.138	Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zinc_ribbon_10 (PF10058, IPR019273): Predicted integral membrane zinc-ribbon metal-binding protein DUF2360 (PF10152, IPR019309): Predicted coiled-coil domain-containing protein (DUF2360) zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain PRIMA1 (PF16101): Proline-rich membrane anchor 1
336	ZNF516	interactor	6	0.600	5.312	zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding zf-C2H2 (PF00096, IPR007087, SM00355): Zinc finger, C2H2 type zf-dskA_traR (PF01258, IPR000962): Prokaryotic dksA/traR C4-type zinc finger zf-H2C2_2 (PF13465, IPR007087): Zinc-finger double domain zf-C2H2_4 (PF13894): C2H2-type zinc finger zf-H2C2_5 (PF13909): C2H2-type zinc-finger domain zf-C2H2_6 (PF13912, IPR007087): C2H2-type zinc finger zf-C2H2_10 (PF16588, IPR001878): C2H2 zinc-finger

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