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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins ABHD12B, ADGRE5 (from a repository: Sat Aug 24 17:23:26 2019)
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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)10
The number (and %) of the onco-proteins3 (30.00 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)9 (20.00 %)
The number (and %) of affected PPIs8 (88.89 %)
The number of possible different fusions2
PPI diameter2
PPI radiusinf
The average degree of PPI1.600
Assortativity coefficient0
The network average Clustering coefficient0.000
The number (and %) of a zero Clustering coefficients10 (100.00 %)
The number (and %) of a zero Betweenness Centrality9 (90.00 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: ADGRE5,ABHD12B All fusions
Proteins found in more fusions HNRNPD (see 1 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 ADGRE5parental protein7042.0007tm_2 (PF00002, IPR000832): 7 transmembrane receptor (Secretin family)
EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain
GPS (PF01825, IPR000203, SM00303): GPCR proteolysis site, GPS, motif
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
EGF_MSP1_1 (PF12946, IPR024730): MSP1 EGF domain 1
2 ABHD12Bparental protein100Abhydrolase_2 (PF02230, IPR003140): Phospholipase/Carboxylesterase
Hydrolase_4 (PF12146, IPR022742): Serine aminopeptidase, S33
3 CD58interactor100Botulinum_HA-17 (PF05588, IPR008903): Clostridium botulinum HA-17 domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
YjgP_YjgQ (PF03739, IPR005495): Predicted permease YjgP/YjgQ family
4 GOLT1Binteractor100Got1 (PF04178, IPR007305): Got1/Sft2-like family
5 HNRNPDoncoprotein200CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain
NID (PF07292, IPR009909): Nmi/IFP 35 domain (NID)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Keratin_2_head (PF16208, IPR032444): Keratin type II head
6 KNL1oncoprotein100DASH_Hsk3 (PF08227, IPR013183): DASH complex subunit Hsk3 like
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
7 LPAR1oncoprotein1007tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
8 TMEM171interactor100TMEM171 (PF15471, IPR029173): Transmembrane protein family 171
9 TMEM63Binteractor100RSN1_7TM (PF02714, IPR003864): Calcium-dependent channel, 7TM region, putative phosphate
Wzy_C (PF04932, IPR007016): O-Antigen ligase
DUF4006 (PF13179, IPR025065): Family of unknown function (DUF4006)
RSN1_TM (PF13967, IPR032880): Late exocytosis, associated with Golgi transport
PHM7_cyt (PF14703, IPR027815): Cytosolic domain of 10TM putative phosphate transporter
10 XRN1interactor100XRN_N (PF03159, IPR004859): XRN 5'-3' exonuclease N-terminus

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