1 |
CRY2 | parental protein | 149 | 0.078 | 12719.406 | DNA_photolyase (PF00875, IPR006050): DNA photolyase FAD_binding_7 (PF03441, IPR005101): FAD binding domain of DNA photolyase |
2 |
ACLY | interactor | 9 | 0.583 | 5.636 | ATP-grasp_2 (PF08442, IPR013650): ATP-grasp domain Citrate_synt (PF00285, IPR002020): Citrate synthase, C-terminal domain CoA_binding (PF02629, IPR003781, SM00881): CoA binding domain Ligase_CoA (PF00549, IPR005811): CoA-ligase Citrate_bind (PF16114, IPR032263): ATP citrate lyase citrate-binding |
3 |
ADAR | interactor | 9 | 0.472 | 10.294 | dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif z-alpha (PF02295, IPR000607, SM00550): Adenosine deaminase z-alpha domain A_deamin (PF02137, IPR002466, SM00552): Adenosine-deaminase (editase) domain |
4 |
AKAP8 | interactor | 7 | 0.571 | 2.109 | AKAP95 (PF04988, IPR007071): A-kinase anchoring protein 95 (AKAP95) Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein |
5 |
ANAPC7 | interactor | 5 | 0.500 | 0.651 | TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat TPR_21 (PF09976, IPR018704): Tetratricopeptide repeat-like domain ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 (PF13176, IPR019734): Tetratricopeptide repeat TPR_14 (PF13428): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat |
6 |
AP2M1 | protein found in more fusions | 16 | 0.305 | 43.522 | Adap_comp_sub (PF00928, IPR008968): Adaptor complexes medium subunit family Clat_adaptor_s (PF01217, IPR022775): Clathrin adaptor complex small chain |
7 |
ARNTL | suppressor | 7 | 0.762 | 2.333 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold PAS_11 (PF14598): PAS domain |
8 |
ATP1A1 | interactor | 6 | 0.733 | 1.556 | Cation_ATPase_C (PF00689, IPR006068): Cation transporting ATPase, C-terminus Cation_ATPase_N (PF00690, IPR004014, SM00831): Cation transporter/ATPase, N-terminus E1-E2_ATPase (PF00122, IPR008250): E1-E2 ATPase Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase Tetraspannin (PF00335, IPR018499): Tetraspanin family Cation_ATPase (PF13246): Cation transport ATPase (P-type) |
9 |
ATP1A3 | interactor | 2 | 1.000 | 0 | Cation_ATPase_C (PF00689, IPR006068): Cation transporting ATPase, C-terminus Cation_ATPase_N (PF00690, IPR004014, SM00831): Cation transporter/ATPase, N-terminus E1-E2_ATPase (PF00122, IPR008250): E1-E2 ATPase Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase Cation_ATPase (PF13246): Cation transport ATPase (P-type) |
10 |
ATXN1 | protein found in more fusions | 9 | 0.464 | 11.167 | AXH (PF08517, IPR013723, SM00536): Ataxin-1 and HBP1 module (AXH) Spt20 (PF12090, IPR021950): Spt20 family ATXN-1_C (PF12547, IPR020997): Capicua transcriptional repressor modulator Cnd1_N (PF12922, IPR024324): non-SMC mitotic condensation complex subunit 1, N-term |
11 |
BAG2 | protein found in more fusions | 11 | 0.422 | 14.990 | IncA (PF04156, IPR007285): IncA protein Mnd1 (PF03962, IPR005647): Mnd1 family ParD_antitoxin (PF03693, IPR022789): Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH |
12 |
BHLHE41 | suppressor | 12 | 0.655 | 8.733 | Adeno_PIX (PF03955, IPR005641): Adenovirus hexon-associated protein (IX) Hairy_orange (PF07527, IPR003650): Hairy Orange HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence |
13 |
BRCA1 | suppressor | 20 | 0.287 | 69.956 | BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT |
14 |
BTRC | oncoprotein | 21 | 0.395 | 52.175 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain F-box-like (PF12937, IPR001810): F-box-like |
15 |
CAND1 | interactor | 50 | 0.181 | 548.716 | Adaptin_N (PF01602, IPR002553): Adaptin N terminal region DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981) HEAT (PF02985, IPR000357): HEAT repeat TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20) RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II |
16 |
CCT2 | interactor | 19 | 0.503 | 37.229 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
17 |
CCT4 | interactor | 18 | 0.497 | 35.511 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
18 |
CCT5 | interactor | 13 | 0.641 | 12.985 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
19 |
CCT6A | interactor | 17 | 0.529 | 27.160 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
20 |
CCT8 | interactor | 16 | 0.567 | 19.465 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
21 |
CKAP4 | protein found in more fusions | 3 | 1.000 | 0 | DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180) FPP (PF05911, IPR008587): Filament-like plant protein, long coiled-coil Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200) |
22 |
CLOCK | interactor | 12 | 0.606 | 12.840 | DivIC (PF04977, IPR007060): Septum formation initiator HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) PAS (PF00989, IPR013767, SM00091): PAS fold RNA_pol_Rpb4 (PF03874, IPR005574): RNA polymerase Rpb4 PAS_11 (PF14598): PAS domain FlgT_N (PF16548, IPR032370): Flagellar assembly protein T, N-terminal domain |
23 |
CNP | interactor | 1 | 0 | 0 | CNPase (PF05881, IPR008431): 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase) NB-ARC (PF00931, IPR002182): NB-ARC domain AAA_33 (PF13671): AAA domain |
24 |
COPA | protein found in more fusions | 8 | 0.381 | 9.130 | Coatomer_WDAD (PF04053, IPR006692): Coatomer WD associated region COPI_C (PF06957, IPR010714): Coatomer (COPI) alpha subunit C-terminus WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
25 |
CRKL | oncoprotein | 5 | 0.500 | 1.571 | SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_2 (PF07653, IPR011511): Variant SH3 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain |
26 |
CRY1 | interactor | 66 | 0.121 | 1346.702 | DNA_photolyase (PF00875, IPR006050): DNA photolyase FAD_binding_7 (PF03441, IPR005101): FAD binding domain of DNA photolyase |
27 |
CSE1L | oncoprotein | 9 | 0.417 | 11.756 | CAS_CSE1 (PF03378, IPR005043): CAS/CSE protein, C-terminus Cse1 (PF08506, IPR013713): Cse1 IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain Xpo1 (PF08389, IPR013598): Exportin 1-like protein |
28 |
CSNK1E | protein found in more fusions | 16 | 0.448 | 35.055 | APH (PF01636, IPR002575): Phosphotransferase enzyme family Pkinase (PF00069, IPR000719): Protein kinase domain |
29 |
CTBP1 | protein found in more fusions | 3 | 1.000 | 0 | 2-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Cellsynth_D (PF03500, IPR022798): Cellulose synthase subunit D |
30 |
CUL1 | suppressor | 51 | 0.219 | 498.691 | Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain |
31 |
DARS | interactor | 10 | 0.556 | 10.300 | tRNA-synt_2 (PF00152, IPR004364): tRNA synthetases class II (D, K and N) tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain |
32 |
DCTPP1 | interactor | 3 | 1.000 | 0 | MazG-like (PF12643, IPR025984): MazG-like family |
33 |
DDB1 | protein found in more fusions | 10 | 0.417 | 6.583 | CPSF_A (PF03178, IPR004871): CPSF A subunit region MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term |
34 |
DDX17 | protein found in more fusions | 16 | 0.457 | 23.009 | CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Ferritin (PF00210, IPR008331): Ferritin-like domain GRP (PF07172, IPR010800): Glycine rich protein family Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
35 |
DDX20 | interactor | 6 | 0.500 | 4.333 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
36 |
DDX3X | suppressor | 14 | 0.374 | 28.142 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755) Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
37 |
DDX3Y | interactor | 1 | 0 | 0 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
38 |
DEC1 | suppressor | 15 | 0.484 | 26.108 | DEC1 (PF15859, IPR031718): Deleted in esophageal cancer 1 family |
39 |
DHX15 | interactor | 10 | 0.644 | 4.707 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2) Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain AAA_29 (PF13555): P-loop containing region of AAA domain |
40 |
DICER1 | suppressor | 5 | 0.500 | 2.500 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif Dicer_dimer (PF03368, IPR005034): Dicer dimerisation domain PAZ (PF02170, IPR003100, SM00949): PAZ domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain Ribonuclease_3 (PF00636, IPR000999, SM00535): Ribonuclease III domain PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4611 (PF15387, IPR027893): Domain of unknown function (DUF4611) |
41 |
DNAJC7 | interactor | 9 | 0.611 | 5.124 | DnaJ (PF00226, IPR001623, SM00271): DnaJ domain TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat Rapsyn_N (PF10579, IPR019568): Rapsyn N-terminal myristoylation and linker region ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 (PF13414, IPR011990): TPR repeat TPR_17 (PF13431): Tetratricopeptide repeat |
42 |
DYNC1H1 | interactor | 9 | 0.500 | 5.842 | AAA_5 (PF07728, IPR011704): AAA domain (dynein-related subfamily) DHC_N1 (PF08385, IPR013594): Dynein heavy chain, N-terminal region 1 DHC_N2 (PF08393, IPR013602): Dynein heavy chain, N-terminal region 2 DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948) Dynein_heavy (PF03028, IPR004273): Dynein heavy chain and region D6 of dynein motor Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family AAA_6 (PF12774): Hydrolytic ATP binding site of dynein motor region D1 AAA_7 (PF12775): P-loop containing dynein motor region D3 MT (PF12777, IPR024743): Microtubule-binding stalk of dynein motor AAA_8 (PF12780, IPR024317): P-loop containing dynein motor region D4 AAA_9 (PF12781): ATP-binding dynein motor region D5 |
43 |
EEF1A1 | suppressor | 29 | 0.299 | 123.678 | GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain |
44 |
EEF1A2 | oncoprotein | 10 | 0.333 | 10.672 | GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain |
45 |
EEF2 | interactor | 21 | 0.395 | 55.939 | EFG_C (PF00679, IPR000640, SM00838): Elongation factor G C-terminus EFG_IV (PF03764, IPR005517, SM00889): Elongation factor G, domain IV GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 EFG_II (PF14492, IPR009022): Elongation Factor G, domain II |
46 |
EFTUD2 | interactor | 17 | 0.367 | 31.981 | EFG_C (PF00679, IPR000640, SM00838): Elongation factor G C-terminus EFG_IV (PF03764, IPR005517, SM00889): Elongation factor G, domain IV GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 EFG_II (PF14492, IPR009022): Elongation Factor G, domain II EFTUD2 (PF16004, IPR031950): 116 kDa U5 small nuclear ribonucleoprotein component N-terminus |
47 |
EIF4A1 | interactor | 11 | 0.564 | 9.111 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
48 |
EIF4A2 | oncoprotein | 7 | 0.467 | 2.963 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
49 |
EPRS | interactor | 14 | 0.484 | 22.927 | GST_C (PF00043, IPR004046): Glutathione S-transferase, C-terminal domain HGTP_anticodon (PF03129, IPR004154): Anticodon binding domain ProRS-C_1 (PF09180, IPR016061, SM00946): Prolyl-tRNA synthetase, C-terminal tRNA-synt_1c (PF00749, IPR020058): tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C (PF03950, IPR020059): tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_2b (PF00587, IPR002314): tRNA synthetase class II core domain (G, H, P, S and T) WHEP-TRS (PF00458, IPR000738, SM00991): WHEP-TRS domain |
50 |
EZH2 | suppressor | 22 | 0.252 | 84.894 | CDC45 (PF02724, IPR003874): CDC45-like protein TCR (PF03638, IPR005172, SM01114): Tesmin/TSO1-like CXC domain, cysteine-rich domain SET (PF00856, IPR001214, SM00317): SET domain EZH2_WD-Binding (PF11616, IPR021654): WD repeat binding protein EZH2 Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal |
51 |
FASN | interactor | 10 | 0.500 | 6.360 | Acyl_transf_1 (PF00698, IPR014043): Acyl transferase domain ADH_zinc_N (PF00107, IPR013149): Zinc-binding dehydrogenase ketoacyl-synt (PF00109, IPR014030): Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C (PF02801, IPR014031): Beta-ketoacyl synthase, C-terminal domain KR (PF08659, IPR013968, SM00130): KR domain L27 (PF02828, IPR014775, SM00569): L27 domain Methyltransf_12 (PF08242, IPR013217): Methyltransferase domain PP-binding (PF00550, IPR009081): Phosphopantetheine attachment site Thioesterase (PF00975, IPR001031): Thioesterase domain YjeF_N (PF03853, IPR004443): YjeF-related protein N-terminus ADH_zinc_N_2 (PF13602): Zinc-binding dehydrogenase PS-DH (PF14765, IPR020807): Polyketide synthase dehydratase KAsynt_C_assoc (PF16197, IPR032821): Ketoacyl-synthetase C-terminal extension |
52 |
FBXL21 | interactor | 4 | 1.000 | 0 | NA |
53 |
FBXL3 | interactor | 6 | 0.867 | 0.195 | F-box-like (PF12937, IPR001810): F-box-like DUF4116 (PF13475, IPR025197): Domain of unknown function (DUF4116) |
54 |
FBXW11 | interactor | 34 | 0.191 | 269.366 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain F-box-like (PF12937, IPR001810): F-box-like |
55 |
FBXW7 | suppressor | 9 | 0.464 | 7.802 | Mem_trans (PF03547, IPR004776): Membrane transport protein WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 F-box-like (PF12937, IPR001810): F-box-like |
56 |
FLNA | suppressor | 10 | 0.422 | 8.357 | CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain Filamin (PF00630, IPR017868): Filamin/ABP280 repeat |
57 |
GARS | interactor | 11 | 0.418 | 20.981 | HGTP_anticodon (PF03129, IPR004154): Anticodon binding domain tRNA-synt_2b (PF00587, IPR002314): tRNA synthetase class II core domain (G, H, P, S and T) WHEP-TRS (PF00458, IPR000738, SM00991): WHEP-TRS domain |
58 |
GCN1 | interactor | 5 | 0.400 | 3.956 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat HEAT (PF02985, IPR000357): HEAT repeat CLASP_N (PF12348, IPR024395): CLASP N terminal MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal TFCD_C (PF12612, IPR022577): Tubulin folding cofactor D C terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II |
59 |
GEMIN5 | interactor | 7 | 0.429 | 7.182 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
60 |
HAT1 | interactor | 4 | 0.667 | 0.444 | Hat1_N (PF10394, IPR019467): Histone acetyl transferase HAT1 N-terminus Acetyltransf_7 (PF13508, IPR000182): Acetyltransferase (GNAT) domain Acetyltransf_10 (PF13673, IPR000182): Acetyltransferase (GNAT) domain |
61 |
HNRNPDL | interactor | 9 | 0.694 | 3.106 | CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) |
62 |
HNRNPK | oncoprotein | 25 | 0.384 | 68.503 | ROKNT (PF08067, IPR012987): ROKNT (NUC014) domain KH_1 (PF00013, IPR004088, SM00322): KH domain |
63 |
HNRNPM | interactor | 18 | 0.412 | 44.713 | RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNP_M (PF11532, IPR024666): Heterogeneous nuclear ribonucleoprotein M Collagen_mid (PF15984, IPR031929): Bacterial collagen, middle region |
64 |
HSP90AA1 | oncoprotein | 44 | 0.213 | 430.500 | HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein |
65 |
HSP90AB1 | oncoprotein | 28 | 0.333 | 104.996 | HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein |
66 |
HSP90AB3P | interactor | 2 | 1.000 | 0 | DUF11 (PF01345, IPR001434): Domain of unknown function DUF11 fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase (PF00069, IPR000719): Protein kinase domain PPAK (PF02818, IPR004168): PPAK motif Titin_Z (PF09042, IPR015129): Titin Z V-set (PF07686, IPR013106): Immunoglobulin V-set domain Y_Y_Y (PF07495, IPR011123): Y_Y_Y domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) Ig_3 (PF13927): Immunoglobulin domain |
67 |
HSPA1A | interactor | 21 | 0.333 | 77.681 | HSP70 (PF00012, IPR013126): Hsp70 protein |
68 |
HSPA7 | interactor | 5 | 0.800 | 0.297 | NA |
69 |
HSPA8 | oncoprotein | 22 | 0.372 | 69.932 | HSP70 (PF00012, IPR013126): Hsp70 protein |
70 |
HSPD1 | suppressor | 12 | 0.606 | 7.110 | Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family |
71 |
HUWE1 | oncoprotein | 53 | 0.179 | 665.658 | BUD22 (PF09073, IPR015158): BUD22 DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908) DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913) FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM) Mucin (PF01456, IPR000458): Mucin-like glycoprotein Nop14 (PF04147, IPR007276): Nop14-like family PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32 RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain WWE (PF02825, IPR004170, SM00678): WWE domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54 U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414) |
72 |
IARS | interactor | 8 | 0.607 | 9.056 | Anticodon_1 (PF08264, IPR013155): Anticodon-binding domain of tRNA tRNA-synt_1 (PF00133, IPR002300): tRNA synthetases class I (I, L, M and V) |
73 |
KHDRBS1 | protein found in more fusions | 13 | 0.409 | 18.372 | KH_1 (PF00013, IPR004088, SM00322): KH domain Qua1 (PF16274, IPR032571): Qua1 domain Sam68-YY (PF16568, IPR032335): Tyrosine-rich domain of Sam68 |
74 |
KHSRP | interactor | 5 | 0.600 | 0.767 | DUF1897 (PF09005, IPR015096): Domain of unknown function (DUF1897) KH_1 (PF00013, IPR004088, SM00322): KH domain |
75 |
KPNA1 | interactor | 10 | 0.378 | 15.056 | Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat IBB (PF01749, IPR002652): Importin beta binding domain Arm_3 (PF16186, IPR032413): Atypical Arm repeat |
76 |
LRPPRC | interactor | 6 | 0.400 | 1.951 | DED (PF01335, IPR001875, SM00031): Death effector domain MA3 (PF02847, IPR003891, SM00544): MA3 domain PPR (PF01535, IPR002885): PPR repeat TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat ApoB100_C (PF12491, IPR022176): Apolipoprotein B100 C terminal PPR_2 (PF13041, IPR002885): PPR repeat family PPR_3 (PF13812, IPR002885): Pentatricopeptide repeat domain TPR_19 (PF14559): Tetratricopeptide repeat PPR_long (PF17177): Pentacotripeptide-repeat region of PROPR |
77 |
MAP4 | oncoprotein | 3 | 0.667 | 0.667 | SdiA-regulated (PF06977, IPR009722): SdiA-regulated Tubulin-binding (PF00418, IPR001084): Tau and MAP protein, tubulin-binding repeat DUF3275 (PF11679, IPR021693): Protein of unknown function (DUF3275) |
78 |
MARS | oncoprotein | 8 | 0.786 | 1.800 | Anticodon_1 (PF08264, IPR013155): Anticodon-binding domain of tRNA DUF16 (PF01519, IPR002862): Protein of unknown function DUF16 GST_C (PF00043, IPR004046): Glutathione S-transferase, C-terminal domain tRNA-synt_1g (PF09334, IPR015413): tRNA synthetases class I (M) WHEP-TRS (PF00458, IPR000738, SM00991): WHEP-TRS domain GST_N_2 (PF13409, IPR004045): Glutathione S-transferase, N-terminal domain |
79 |
MATR3 | interactor | 19 | 0.405 | 41.250 | DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-U1 (PF06220, IPR013085, SM00451): U1 zinc finger Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54 zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAM60A (PF15396, IPR026065): Protein Family FAM60A |
80 |
MCM4 | interactor | 10 | 0.528 | 5.880 | MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain |
81 |
MCM5 | oncoprotein | 18 | 0.255 | 56.841 | MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain |
82 |
MCM7 | protein found in more fusions | 11 | 0.400 | 15.894 | MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain |
83 |
MTHFD1 | interactor | 5 | 0.500 | 1.148 | FTHFS (PF01268, IPR000559): Formate--tetrahydrofolate ligase THF_DHG_CYH (PF00763, IPR020630): Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C (PF02882, IPR020631): Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain |
84 |
MTUS2 | suppressor | 2 | 0 | 0 | DUF496 (PF04363, IPR007458): Protein of unknown function (DUF496) RNA_pol_Rpb1_R (PF05001, IPR000684): RNA polymerase Rpb1 C-terminal repeat FAM184 (PF15665): Family with sequence similarity 184, A and B |
85 |
MYCBP2 | interactor | 5 | 0.600 | 2.567 | ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10) Filamin (PF00630, IPR017868): Filamin/ABP280 repeat Peptidase_S49_N (PF08496, IPR013703): Peptidase family S49 N-terminal PHR (PF08005, IPR012983): PHR domain RCC1 (PF00415, IPR000408): Regulator of chromosome condensation (RCC1) repeat SH3_3 (PF08239, IPR003646): Bacterial SH3 domain XPA_N (PF01286, IPR022652): XPA protein N-terminal zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain RCC1_2 (PF13540): Regulator of chromosome condensation (RCC1) repeat |
86 |
NCL | protein found in more fusions | 17 | 0.367 | 35.750 | DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) Myc_N (PF01056, IPR012682): Myc amino-terminal region RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YL1 (PF05764, IPR008895): YL1 nuclear protein Limkain-b1 (PF11608, IPR024582): Limkain b1 |
87 |
NONO | oncoprotein | 9 | 0.429 | 8.608 | GvpL_GvpF (PF06386, IPR009430): Gas vesicle synthesis protein GvpL/GvpF NOPS (PF08075, IPR012975): NOPS (NUC059) domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAS_7 (PF12860): PAS fold SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3 |
88 |
NPAS2 | suppressor | 6 | 0.800 | 1.433 | HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold DehI (PF10778, IPR019714): Halocarboxylic acid dehydrogenase DehI PAS_11 (PF14598): PAS domain |
89 |
NXF1 | interactor | 44 | 0.165 | 515.549 | NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain LRR_8 (PF13855, IPR001611): Leucine rich repeat |
90 |
NXN | interactor | 1 | 0 | 0 | Thioredoxin_6 (PF13848): Thioredoxin-like domain Thioredoxin_8 (PF13905, IPR012336): Thioredoxin-like |
91 |
PAICS | interactor | 7 | 0.667 | 2.567 | AIRC (PF00731, IPR000031, SM01001): AIR carboxylase SAICAR_synt (PF01259, IPR028923): SAICAR synthetase |
92 |
PCBP1 | oncoprotein | 11 | 0.564 | 7.992 | Bac_chlorC (PF02043, IPR001470): Bacteriochlorophyll C binding protein KH_2 (PF07650, IPR004044): KH domain KH_1 (PF00013, IPR004088, SM00322): KH domain |
93 |
PDE9A | interactor | 2 | 0 | 0 | PDEase_I (PF00233, IPR002073): 3'5'-cyclic nucleotide phosphodiesterase |
94 |
PER1 | oncoprotein | 10 | 0.467 | 13.467 | PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold SPX (PF03105, IPR004331): SPX domain SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein Period_C (PF12114, IPR022728): Period protein 2/3C-terminal region |
95 |
PER2 | suppressor | 9 | 0.639 | 6.145 | PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold Period_C (PF12114, IPR022728): Period protein 2/3C-terminal region |
96 |
PER3 | interactor | 4 | 0.833 | 0.286 | PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold DNA_Packaging (PF11053, IPR020342): Terminase DNA packaging enzyme Period_C (PF12114, IPR022728): Period protein 2/3C-terminal region |
97 |
PHGDH | interactor | 9 | 0.361 | 8.590 | 2-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain |
98 |
PPP2CB | suppressor | 15 | 0.524 | 29.148 | Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain |
99 |
PPP2R1B | suppressor | 14 | 0.474 | 23.271 | HEAT (PF02985, IPR000357): HEAT repeat Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_2 (PF13646): HEAT repeats |
100 |
PPP2R2A | interactor | 11 | 0.691 | 6.658 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Y_phosphatase2 (PF03162, IPR004861): Tyrosine phosphatase family ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
101 |
PPP2R2D | interactor | 11 | 0.655 | 10.138 | WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Y_phosphatase2 (PF03162, IPR004861): Tyrosine phosphatase family ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain |
102 |
PPP2R5D | interactor | 9 | 0.667 | 6.186 | B56 (PF01603, IPR002554): Protein phosphatase 2A regulatory B subunit (B56 family) |
103 |
PPP2R5E | protein found in more fusions | 10 | 0.778 | 2.281 | B56 (PF01603, IPR002554): Protein phosphatase 2A regulatory B subunit (B56 family) |
104 |
PPP5C | interactor | 9 | 0.556 | 6.375 | Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase PPP5 (PF08321, IPR013235): PPP5 TPR repeat region TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_17 (PF13431): Tetratricopeptide repeat |
105 |
PRKDC | protein found in more fusions | 14 | 0.359 | 20.756 | FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain NUC194 (PF08163, IPR012582): NUC194 domain PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase |
106 |
PRMT1 | interactor | 13 | 0.470 | 15.275 | Methyltransf_25 (PF13649): Methyltransferase domain |
107 |
PSMC2 | protein found in more fusions | 19 | 0.464 | 41.414 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) |
108 |
PSMC3 | interactor | 14 | 0.603 | 20.391 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) DUF3713 (PF12506, IPR022186): Protein of unknown function (DUF3713) JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II |
109 |
PSMC4 | interactor | 15 | 0.552 | 23.611 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) NTPase_1 (PF03266, IPR004948): NTPase CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_16 (PF13191): AAA ATPase domain |
110 |
PSMC5 | protein found in more fusions | 13 | 0.727 | 6.302 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) Laminin_II (PF06009, IPR010307): Laminin Domain II RILP (PF11461, IPR021563): Rab interacting lysosomal protein AAA_16 (PF13191): AAA ATPase domain |
111 |
PSMD1 | interactor | 16 | 0.492 | 29.822 | PA26 (PF04636, IPR006730): PA26 p53-induced protein (sestrin) PC_rep (PF01851, IPR002015): Proteasome/cyclosome repeat HEAT_2 (PF13646): HEAT repeats |
112 |
PSMD11 | interactor | 11 | 0.800 | 3.852 | DUF247 (PF03140, IPR004158): Plant protein of unknown function PCI (PF01399, IPR000717, SM00088): PCI domain AAA_16 (PF13191): AAA ATPase domain TPR_12 (PF13424): Tetratricopeptide repeat |
113 |
PSMD2 | oncoprotein | 13 | 0.654 | 11.407 | PC_rep (PF01851, IPR002015): Proteasome/cyclosome repeat THAP (PF05485, IPR006612, SM00980): THAP domain HEAT_2 (PF13646): HEAT repeats |
114 |
PSMD3 | interactor | 11 | 0.855 | 1.739 | Rpn3_C (PF08375, IPR013586): Proteasome regulatory subunit C-terminal TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat PCI (PF01399, IPR000717, SM00088): PCI domain Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat TSKS (PF15358, IPR028214): Testis-specific serine kinase substrate |
115 |
QPRT | interactor | 4 | 1.000 | 0 | QRPTase_C (PF01729, IPR002638): Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N (PF02749, IPR022412): Quinolinate phosphoribosyl transferase, N-terminal domain |
116 |
RAN | oncoprotein | 6 | 0.667 | 2.071 | Ras (PF00071, IPR001806, SM00173): Ras family |
117 |
RANBP2 | oncoprotein | 20 | 0.345 | 54.153 | Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat Ran_BP1 (PF00638, IPR000156, SM00160): RanBP1 domain zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others DUF2693 (PF10902, IPR024401): Protein of unknown function (DUF2693) IR1-M (PF12185, IPR022011): Nup358/RanBP2 E3 ligase domain Dmrt1 (PF12374, IPR022114): Double-sex mab3 related transcription factor 1 TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat TPR_11 (PF13414, IPR011990): TPR repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat |
118 |
RNF219 | interactor | 2 | 1.000 | 0 | CENP-Q (PF13094, IPR025212): CENP-Q, a CENPA-CAD centromere complex subunit zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain |
119 |
RPL10 | suppressor | 10 | 0.711 | 2.926 | Ribosomal_L16 (PF00252, IPR016180): Ribosomal protein L16p/L10e |
120 |
RPN1 | oncoprotein | 10 | 0.444 | 14.171 | Ribophorin_I (PF04597, IPR007676): Ribophorin I CtIP_N (PF10482, IPR019518): Tumour-suppressor protein CtIP N-terminal domain |
121 |
RPS14 | interactor | 13 | 0.641 | 6.458 | Ribosomal_S11 (PF00411, IPR001971): Ribosomal protein S11 |
122 |
RPS17 | interactor | 9 | 0.750 | 1.587 | Ribosomal_S17e (PF00833, IPR001210): Ribosomal S17 |
123 |
RPS2 | interactor | 18 | 0.477 | 34.964 | Ribosomal_S5 (PF00333, IPR013810): Ribosomal protein S5, N-terminal domain Ribosomal_S5_C (PF03719, IPR005324): Ribosomal protein S5, C-terminal domain |
124 |
RPS3 | interactor | 19 | 0.503 | 27.918 | KH_2 (PF07650, IPR004044): KH domain Ribosomal_S3_C (PF00189, IPR001351): Ribosomal protein S3, C-terminal domain |
125 |
RPS6 | interactor | 17 | 0.574 | 16.897 | Ribosomal_S6e (PF01092, IPR001377): Ribosomal protein S6e DUF4574 (PF15141, IPR027896): Domain of unknown function (DUF4574) |
126 |
RUVBL2 | oncoprotein | 21 | 0.347 | 52.270 | TIP49 (PF06068, IPR010339): TIP49 C-terminus |
127 |
SDHA | suppressor | 10 | 0.467 | 12.056 | FAD_binding_2 (PF00890, IPR003953): FAD binding domain Succ_DH_flav_C (PF02910, IPR015939): Fumarate reductase flavoprotein C-term |
128 |
SEC16A | interactor | 7 | 0.619 | 3.219 | APC_r (PF05923): APC repeat Sec16_C (PF12931, IPR024298): Sec23-binding domain of Sec16 Sec16 (PF12932, IPR024340): Vesicle coat trafficking protein Sec16 mid-region |
129 |
SKP1 | oncoprotein | 12 | 0.545 | 12.590 | Skp1 (PF01466, IPR016072, SM00512): Skp1 family, dimerisation domain Skp1_POZ (PF03931, IPR016073): Skp1 family, tetramerisation domain |
130 |
SMC2 | interactor | 3 | 0.667 | 1.000 | SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200) DUF4201 (PF13870, IPR025254): Domain of unknown function (DUF4201) |
131 |
SMC4 | interactor | 2 | 1.000 | 0 | SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain Caskin-Pro-rich (PF16907): Proline rich region of Caskin proteins |
132 |
SNRNP200 | protein found in more fusions | 13 | 0.439 | 16.460 | DEAD (PF00270, IPR011545): DEAD/DEAH box helicase DUF603 (PF04645, IPR006739): Protein of unknown function, DUF603 Sec63 (PF02889, IPR004179, SM00973): Sec63 Brl domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain |
133 |
SRM | interactor | 2 | 1.000 | 0 | Spermine_synth (PF01564, IPR001045): Spermine/spermidine synthase |
134 |
STK11 | suppressor | 6 | 0.467 | 3.697 | Pkinase (PF00069, IPR000719): Protein kinase domain |
135 |
TEKT4 | interactor | 4 | 0.667 | 1.222 | Tektin (PF03148, IPR000435): Tektin family |
136 |
TIMELESS | interactor | 2 | 1.000 | 0 | Myc_N (PF01056, IPR012682): Myc amino-terminal region TIMELESS (PF04821, IPR006906): Timeless protein TIMELESS_C (PF05029, IPR007725): Timeless protein C terminal region Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain |
137 |
TMPO | interactor | 3 | 0.667 | 0.333 | LEM (PF03020, IPR003887, SM00540): LEM domain Thymopoietin (PF08198, IPR013146): Thymopoietin protein LAP2alpha (PF11560, IPR021623): Lamina-associated polypeptide 2 alpha |
138 |
TTC1 | interactor | 9 | 0.361 | 13.350 | TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat |
139 |
TUFM | interactor | 9 | 0.611 | 7.038 | GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain |
140 |
UBR5 | protein found in more fusions | 10 | 0.306 | 11.077 | CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain SDA1 (PF05285, IPR007949): SDA1 HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain E3_UbLigase_EDD (PF11547, IPR024725): E3 ubiquitin ligase EDD PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein |
141 |
USP11 | protein found in more fusions | 10 | 0.444 | 10.880 | Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase DUSP (PF06337, IPR006615, SM00695): DUSP domain Ubiquitin_3 (PF14836, IPR028135): Ubiquitin-like domain |
142 |
USP7 | oncoprotein | 19 | 0.248 | 79.625 | MATH (PF00917, IPR002083, SM00061): MATH domain UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg (PF12436, IPR024729): ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 (PF14533, IPR029346): Ubiquitin-specific protease C-terminal |
143 |
USP9X | interactor | 11 | 0.436 | 20.251 | DUF1722 (PF08349, IPR013560): Protein of unknown function (DUF1722) UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase Utp13 (PF08625, IPR013934): Utp13 specific WD40 associated domain |
144 |
VCP | protein found in more fusions | 37 | 0.244 | 268.045 | AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2 CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain TniB (PF05621, IPR008868): Bacterial TniB protein Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944) |
145 |
XPO1 | interactor | 41 | 0.173 | 437.602 | CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain Xpo1 (PF08389, IPR013598): Exportin 1-like protein Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region |
146 |
XRCC6 | oncoprotein | 11 | 0.400 | 11.262 | Ku (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain SAP (PF02037, IPR003034, SM00513): SAP domain |
147 |
XRN2 | interactor | 7 | 0.714 | 1.238 | XRN_N (PF03159, IPR004859): XRN 5'-3' exonuclease N-terminus |
148 |
YWHAE | oncoprotein | 18 | 0.431 | 38.740 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |
149 |
YWHAQ | interactor | 19 | 0.263 | 69.344 | 14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein |