Find Fusion Network

Visualization interactions

Powered by Cytoscape Web for: parental proteins CRY2 (from a repository: Wed Nov 16 06:53:39 2016)

Examples AFF1 MLL ACTN4 + MLLAFF1 + MLLALK + MSNALK + TFGALK + TPM3ALK + TPM4ASXL2 + KAT6AATF1 + FUSBCR + ABL1BCR + FGFR1CCND1 + TACSTD2CD74 + ROS1CDK6 + MLLCOL1A1 + PDGFBCREB3L2 + PPARGCREB3L2 + FUSCREBBP + KAT6ADAZAP1 + MEF2DELL + MLLEPS15 + MLLERG + EWSR1ERG + FUSERG + TMPRSS2ETV5 + TMPRSS2ETV6 + ABL1ETV6 + NTRK3ETV6 + PAX5EWSR1 + FLI1EWSR1 + WT1FOXO1 + PAX3FOXP1 + PAX5FRYL + MLLGAS7 + MLLGMPS + MLLGOLGA5 + RETHOOK3 + RETHOXC13 + NUP98HOXD13 + NUP98MECOM + RUNX1MKL1 + RBM15MLL + MLLT1MLL + MLLT4MLL + MLLT10MLL + PICALMMLLT10 + PICALMNCOA1 + PAX3NIN + PDGFRBNPM1 + RARANRG1 + ODZ4NTRK1 + TFGNUMA1 + RARANUP98 + PHF23PAX5 + ZNF521PBX1 + TCF3RET + TRIM27ROS1 + SLC34A2PML + RARAPRKAR1A + RARAPRKAR1A + RETRUNX1 + RUNX1T1RUNX1 + SH3D19	Cytoscape Web will replace the contents your graph	PPI Properties: Click on nodes or edges
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Statistics and Network structure information

Statistic of PPI Value(s) The number of interactors (fusion and proteins) 149 The number (and %) of the onco-proteins 45 (30.20 %) The number (and %) of the tumor suppressors 20 (13.42 %) Total number of binary PPIs (saturation %) 1055 (9.57 %) The number (and %) of affected PPIs 149 (14.12 %) The number of possible different fusions 29 PPI diameter 2 PPI radius 1 The average degree of PPI 13.383 Assortativity coefficient -0.2255 The network average Clustering coefficient 0.513 The number (and %) of a zero Clustering coefficients 5 (3.36 %) The number (and %) of a zero Betweenness Centrality 16 (10.74 %)

ACTIVE INTERACTORS

List of the fusions
PPI for parental proteins: CRY2	All fusions : W26687; BI004402;
Proteins found in more fusions	PSMC2 (see 1 fusions); CTBP1 (see 2 fusions); CKAP4 (see 5 fusions); CUL1 (see 3 fusions); PRKDC (see 3 fusions); PPP2R5E (see 1 fusions); AP2M1 (see 3 fusions); MCM7 (see 2 fusions); CRY2 (see 3 fusions); VCP (see 4 fusions); HSP90AA1 (see 2 fusions); HUWE1 (see 2 fusions); ATXN1 (see 3 fusions); HSP90AB1 (see 1 fusions); BAG2 (see 1 fusions); SNRNP200 (see 3 fusions); KHDRBS1 (see 1 fusions); COPA (see 2 fusions); EIF4A2 (see 2 fusions); UBR5 (see 4 fusions); DDX17 (see 3 fusions); EZH2 (see 1 fusions); DDB1 (see 2 fusions); PSMC5 (see 2 fusions); CSNK1E (see 1 fusions); USP11 (see 4 fusions); NCL (see 3 fusions); HSPA8/HSPD1 (see 1 fusions);

List of active interactors

#	Name	Type	Number of PPI (degree)	Clustering Coefficient	Betweenness Centrality	Domains (Pfam, InterPro, SMART): description
1	CRY2	parental protein	149	0.078	12719.406	DNA_photolyase (PF00875, IPR006050): DNA photolyase FAD_binding_7 (PF03441, IPR005101): FAD binding domain of DNA photolyase
2	ACLY	interactor	9	0.583	5.636	ATP-grasp_2 (PF08442, IPR013650): ATP-grasp domain Citrate_synt (PF00285, IPR002020): Citrate synthase, C-terminal domain CoA_binding (PF02629, IPR003781, SM00881): CoA binding domain Ligase_CoA (PF00549, IPR005811): CoA-ligase Citrate_bind (PF16114, IPR032263): ATP citrate lyase citrate-binding
3	ADAR	interactor	9	0.472	10.294	dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif z-alpha (PF02295, IPR000607, SM00550): Adenosine deaminase z-alpha domain A_deamin (PF02137, IPR002466, SM00552): Adenosine-deaminase (editase) domain
4	AKAP8	interactor	7	0.571	2.109	AKAP95 (PF04988, IPR007071): A-kinase anchoring protein 95 (AKAP95) Herpes_PAP (PF03325, IPR004997): Herpesvirus polymerase accessory protein
5	ANAPC7	interactor	5	0.500	0.651	TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat TPR_21 (PF09976, IPR018704): Tetratricopeptide repeat-like domain ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 (PF13176, IPR019734): Tetratricopeptide repeat TPR_14 (PF13428): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat
6	AP2M1	protein found in more fusions	16	0.305	43.522	Adap_comp_sub (PF00928, IPR008968): Adaptor complexes medium subunit family Clat_adaptor_s (PF01217, IPR022775): Clathrin adaptor complex small chain
7	ARNTL	suppressor	7	0.762	2.333	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold PAS_11 (PF14598): PAS domain
8	ATP1A1	interactor	6	0.733	1.556	Cation_ATPase_C (PF00689, IPR006068): Cation transporting ATPase, C-terminus Cation_ATPase_N (PF00690, IPR004014, SM00831): Cation transporter/ATPase, N-terminus E1-E2_ATPase (PF00122, IPR008250): E1-E2 ATPase Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase Tetraspannin (PF00335, IPR018499): Tetraspanin family Cation_ATPase (PF13246): Cation transport ATPase (P-type)
9	ATP1A3	interactor	2	1.000	0	Cation_ATPase_C (PF00689, IPR006068): Cation transporting ATPase, C-terminus Cation_ATPase_N (PF00690, IPR004014, SM00831): Cation transporter/ATPase, N-terminus E1-E2_ATPase (PF00122, IPR008250): E1-E2 ATPase Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase Cation_ATPase (PF13246): Cation transport ATPase (P-type)
10	ATXN1	protein found in more fusions	9	0.464	11.167	AXH (PF08517, IPR013723, SM00536): Ataxin-1 and HBP1 module (AXH) Spt20 (PF12090, IPR021950): Spt20 family ATXN-1_C (PF12547, IPR020997): Capicua transcriptional repressor modulator Cnd1_N (PF12922, IPR024324): non-SMC mitotic condensation complex subunit 1, N-term
11	BAG2	protein found in more fusions	11	0.422	14.990	IncA (PF04156, IPR007285): IncA protein Mnd1 (PF03962, IPR005647): Mnd1 family ParD_antitoxin (PF03693, IPR022789): Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH
12	BHLHE41	suppressor	12	0.655	8.733	Adeno_PIX (PF03955, IPR005641): Adenovirus hexon-associated protein (IX) Hairy_orange (PF07527, IPR003650): Hairy Orange HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence
13	BRCA1	suppressor	20	0.287	69.956	BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT
14	BTRC	oncoprotein	21	0.395	52.175	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain F-box-like (PF12937, IPR001810): F-box-like
15	CAND1	interactor	50	0.181	548.716	Adaptin_N (PF01602, IPR002553): Adaptin N terminal region DUF1981 (PF09324, IPR015403): Domain of unknown function (DUF1981) HEAT (PF02985, IPR000357): HEAT repeat TIP120 (PF08623, IPR013932): TATA-binding protein interacting (TIP20) RTP1_C1 (PF10363, IPR019451): Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 (PF11865, IPR024585): Domain of unknown function (DUF3385) MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II
16	CCT2	interactor	19	0.503	37.229	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
17	CCT4	interactor	18	0.497	35.511	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
18	CCT5	interactor	13	0.641	12.985	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
19	CCT6A	interactor	17	0.529	27.160	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
20	CCT8	interactor	16	0.567	19.465	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
21	CKAP4	protein found in more fusions	3	1.000	0	DUF1180 (PF06679, IPR009565): Protein of unknown function (DUF1180) FPP (PF05911, IPR008587): Filament-like plant protein, long coiled-coil Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family Reo_sigmaC (PF04582, IPR007662): Reovirus sigma C capsid protein DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
22	CLOCK	interactor	12	0.606	12.840	DivIC (PF04977, IPR007060): Septum formation initiator HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like) PAS (PF00989, IPR013767, SM00091): PAS fold RNA_pol_Rpb4 (PF03874, IPR005574): RNA polymerase Rpb4 PAS_11 (PF14598): PAS domain FlgT_N (PF16548, IPR032370): Flagellar assembly protein T, N-terminal domain
23	CNP	interactor	1	0	0	CNPase (PF05881, IPR008431): 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase) NB-ARC (PF00931, IPR002182): NB-ARC domain AAA_33 (PF13671): AAA domain
24	COPA	protein found in more fusions	8	0.381	9.130	Coatomer_WDAD (PF04053, IPR006692): Coatomer WD associated region COPI_C (PF06957, IPR010714): Coatomer (COPI) alpha subunit C-terminus WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
25	CRKL	oncoprotein	5	0.500	1.571	SH2 (PF00017, IPR000980, SM00252): SH2 domain SH3_2 (PF07653, IPR011511): Variant SH3 domain SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
26	CRY1	interactor	66	0.121	1346.702	DNA_photolyase (PF00875, IPR006050): DNA photolyase FAD_binding_7 (PF03441, IPR005101): FAD binding domain of DNA photolyase
27	CSE1L	oncoprotein	9	0.417	11.756	CAS_CSE1 (PF03378, IPR005043): CAS/CSE protein, C-terminus Cse1 (PF08506, IPR013713): Cse1 IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain Xpo1 (PF08389, IPR013598): Exportin 1-like protein
28	CSNK1E	protein found in more fusions	16	0.448	35.055	APH (PF01636, IPR002575): Phosphotransferase enzyme family Pkinase (PF00069, IPR000719): Protein kinase domain
29	CTBP1	protein found in more fusions	3	1.000	0	2-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Cellsynth_D (PF03500, IPR022798): Cellulose synthase subunit D
30	CUL1	suppressor	51	0.219	498.691	Cullin (PF00888, IPR001373, SM00182): Cullin family Cullin_Nedd8 (PF10557, IPR019559, SM00884): Cullin protein neddylation domain
31	DARS	interactor	10	0.556	10.300	tRNA-synt_2 (PF00152, IPR004364): tRNA synthetases class II (D, K and N) tRNA_anti-codon (PF01336, IPR004365): OB-fold nucleic acid binding domain
32	DCTPP1	interactor	3	1.000	0	MazG-like (PF12643, IPR025984): MazG-like family
33	DDB1	protein found in more fusions	10	0.417	6.583	CPSF_A (PF03178, IPR004871): CPSF A subunit region MMS1_N (PF10433): Mono-functional DNA-alkylating methyl methanesulfonate N-term
34	DDX17	protein found in more fusions	16	0.457	23.009	CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Ferritin (PF00210, IPR008331): Ferritin-like domain GRP (PF07172, IPR010800): Glycine rich protein family Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
35	DDX20	interactor	6	0.500	4.333	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
36	DDX3X	suppressor	14	0.374	28.142	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755) Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
37	DDX3Y	interactor	1	0	0	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
38	DEC1	suppressor	15	0.484	26.108	DEC1 (PF15859, IPR031718): Deleted in esophageal cancer 1 family
39	DHX15	interactor	10	0.644	4.707	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase OB_NTP_bind (PF07717, IPR011709): Oligonucleotide/oligosaccharide-binding (OB)-fold DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) HA2 (PF04408, IPR007502, SM00847): Helicase associated domain (HA2) Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain AAA_29 (PF13555): P-loop containing region of AAA domain
40	DICER1	suppressor	5	0.500	2.500	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase dsrm (PF00035, IPR014720, SM00358): Double-stranded RNA binding motif Dicer_dimer (PF03368, IPR005034): Dicer dimerisation domain PAZ (PF02170, IPR003100, SM00949): PAZ domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain Ribonuclease_3 (PF00636, IPR000999, SM00535): Ribonuclease III domain PBP1_TM (PF14812, IPR032730): Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4611 (PF15387, IPR027893): Domain of unknown function (DUF4611)
41	DNAJC7	interactor	9	0.611	5.124	DnaJ (PF00226, IPR001623, SM00271): DnaJ domain TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat Rapsyn_N (PF10579, IPR019568): Rapsyn N-terminal myristoylation and linker region ANAPC3 (PF12895): Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 (PF13414, IPR011990): TPR repeat TPR_17 (PF13431): Tetratricopeptide repeat
42	DYNC1H1	interactor	9	0.500	5.842	AAA_5 (PF07728, IPR011704): AAA domain (dynein-related subfamily) DHC_N1 (PF08385, IPR013594): Dynein heavy chain, N-terminal region 1 DHC_N2 (PF08393, IPR013602): Dynein heavy chain, N-terminal region 2 DUF1664 (PF07889, IPR012458): Protein of unknown function (DUF1664) DUF948 (PF06103, IPR009293): Bacterial protein of unknown function (DUF948) Dynein_heavy (PF03028, IPR004273): Dynein heavy chain and region D6 of dynein motor Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family AAA_6 (PF12774): Hydrolytic ATP binding site of dynein motor region D1 AAA_7 (PF12775): P-loop containing dynein motor region D3 MT (PF12777, IPR024743): Microtubule-binding stalk of dynein motor AAA_8 (PF12780, IPR024317): P-loop containing dynein motor region D4 AAA_9 (PF12781): ATP-binding dynein motor region D5
43	EEF1A1	suppressor	29	0.299	123.678	GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain
44	EEF1A2	oncoprotein	10	0.333	10.672	GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain
45	EEF2	interactor	21	0.395	55.939	EFG_C (PF00679, IPR000640, SM00838): Elongation factor G C-terminus EFG_IV (PF03764, IPR005517, SM00889): Elongation factor G, domain IV GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 EFG_II (PF14492, IPR009022): Elongation Factor G, domain II
46	EFTUD2	interactor	17	0.367	31.981	EFG_C (PF00679, IPR000640, SM00838): Elongation factor G C-terminus EFG_IV (PF03764, IPR005517, SM00889): Elongation factor G, domain IV GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 EFG_II (PF14492, IPR009022): Elongation Factor G, domain II EFTUD2 (PF16004, IPR031950): 116 kDa U5 small nuclear ribonucleoprotein component N-terminus
47	EIF4A1	interactor	11	0.564	9.111	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
48	EIF4A2	oncoprotein	7	0.467	2.963	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
49	EPRS	interactor	14	0.484	22.927	GST_C (PF00043, IPR004046): Glutathione S-transferase, C-terminal domain HGTP_anticodon (PF03129, IPR004154): Anticodon binding domain ProRS-C_1 (PF09180, IPR016061, SM00946): Prolyl-tRNA synthetase, C-terminal tRNA-synt_1c (PF00749, IPR020058): tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C (PF03950, IPR020059): tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_2b (PF00587, IPR002314): tRNA synthetase class II core domain (G, H, P, S and T) WHEP-TRS (PF00458, IPR000738, SM00991): WHEP-TRS domain
50	EZH2	suppressor	22	0.252	84.894	CDC45 (PF02724, IPR003874): CDC45-like protein TCR (PF03638, IPR005172, SM01114): Tesmin/TSO1-like CXC domain, cysteine-rich domain SET (PF00856, IPR001214, SM00317): SET domain EZH2_WD-Binding (PF11616, IPR021654): WD repeat binding protein EZH2 Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
51	FASN	interactor	10	0.500	6.360	Acyl_transf_1 (PF00698, IPR014043): Acyl transferase domain ADH_zinc_N (PF00107, IPR013149): Zinc-binding dehydrogenase ketoacyl-synt (PF00109, IPR014030): Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C (PF02801, IPR014031): Beta-ketoacyl synthase, C-terminal domain KR (PF08659, IPR013968, SM00130): KR domain L27 (PF02828, IPR014775, SM00569): L27 domain Methyltransf_12 (PF08242, IPR013217): Methyltransferase domain PP-binding (PF00550, IPR009081): Phosphopantetheine attachment site Thioesterase (PF00975, IPR001031): Thioesterase domain YjeF_N (PF03853, IPR004443): YjeF-related protein N-terminus ADH_zinc_N_2 (PF13602): Zinc-binding dehydrogenase PS-DH (PF14765, IPR020807): Polyketide synthase dehydratase KAsynt_C_assoc (PF16197, IPR032821): Ketoacyl-synthetase C-terminal extension
52	FBXL21	interactor	4	1.000	0	NA
53	FBXL3	interactor	6	0.867	0.195	F-box-like (PF12937, IPR001810): F-box-like DUF4116 (PF13475, IPR025197): Domain of unknown function (DUF4116)
54	FBXW11	interactor	34	0.191	269.366	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Beta-TrCP_D (PF12125, IPR021977, SM01028): D domain of beta-TrCP ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain F-box-like (PF12937, IPR001810): F-box-like
55	FBXW7	suppressor	9	0.464	7.802	Mem_trans (PF03547, IPR004776): Membrane transport protein WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Nup160 (PF11715, IPR021717): Nucleoporin Nup120/160 F-box-like (PF12937, IPR001810): F-box-like
56	FLNA	suppressor	10	0.422	8.357	CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain Filamin (PF00630, IPR017868): Filamin/ABP280 repeat
57	GARS	interactor	11	0.418	20.981	HGTP_anticodon (PF03129, IPR004154): Anticodon binding domain tRNA-synt_2b (PF00587, IPR002314): tRNA synthetase class II core domain (G, H, P, S and T) WHEP-TRS (PF00458, IPR000738, SM00991): WHEP-TRS domain
58	GCN1	interactor	5	0.400	3.956	Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat HEAT (PF02985, IPR000357): HEAT repeat CLASP_N (PF12348, IPR024395): CLASP N terminal MMS19_C (PF12460, IPR024687): RNAPII transcription regulator C-terminal TFCD_C (PF12612, IPR022577): Tubulin folding cofactor D C terminal Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_EZ (PF13513): HEAT-like repeat HEAT_2 (PF13646): HEAT repeats MMS19_N (PF14500): Dos2-interacting transcription regulator of RNA-Pol-II
59	GEMIN5	interactor	7	0.429	7.182	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
60	HAT1	interactor	4	0.667	0.444	Hat1_N (PF10394, IPR019467): Histone acetyl transferase HAT1 N-terminus Acetyltransf_7 (PF13508, IPR000182): Acetyltransferase (GNAT) domain Acetyltransf_10 (PF13673, IPR000182): Acetyltransferase (GNAT) domain
61	HNRNPDL	interactor	9	0.694	3.106	CBFNT (PF08143, IPR012956): CBFNT (NUC161) domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
62	HNRNPK	oncoprotein	25	0.384	68.503	ROKNT (PF08067, IPR012987): ROKNT (NUC014) domain KH_1 (PF00013, IPR004088, SM00322): KH domain
63	HNRNPM	interactor	18	0.412	44.713	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HnRNP_M (PF11532, IPR024666): Heterogeneous nuclear ribonucleoprotein M Collagen_mid (PF15984, IPR031929): Bacterial collagen, middle region
64	HSP90AA1	oncoprotein	44	0.213	430.500	HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein
65	HSP90AB1	oncoprotein	28	0.333	104.996	HATPase_c (PF02518, IPR003594, SM00387): Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HSP90 (PF00183, IPR001404): Hsp90 protein
66	HSP90AB3P	interactor	2	1.000	0	DUF11 (PF01345, IPR001434): Domain of unknown function DUF11 fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase (PF00069, IPR000719): Protein kinase domain PPAK (PF02818, IPR004168): PPAK motif Titin_Z (PF09042, IPR015129): Titin Z V-set (PF07686, IPR013106): Immunoglobulin V-set domain Y_Y_Y (PF07495, IPR011123): Y_Y_Y domain DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369) Ig_3 (PF13927): Immunoglobulin domain
67	HSPA1A	interactor	21	0.333	77.681	HSP70 (PF00012, IPR013126): Hsp70 protein
68	HSPA7	interactor	5	0.800	0.297	NA
69	HSPA8	oncoprotein	22	0.372	69.932	HSP70 (PF00012, IPR013126): Hsp70 protein
70	HSPD1	suppressor	12	0.606	7.110	Cpn60_TCP1 (PF00118, IPR002423): TCP-1/cpn60 chaperonin family
71	HUWE1	oncoprotein	53	0.179	665.658	BUD22 (PF09073, IPR015158): BUD22 DUF908 (PF06012, IPR010309): Domain of Unknown Function (DUF908) DUF913 (PF06025, IPR010314): Domain of Unknown Function (DUF913) FdhE (PF04216, IPR006452): Protein involved in formate dehydrogenase formation HABP4_PAI-RBP1 (PF04774, IPR006861): Hyaluronan / mRNA binding family Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Merozoite_SPAM (PF07133, IPR010784): Merozoite surface protein (SPAM) Mucin (PF01456, IPR000458): Mucin-like glycoprotein Nop14 (PF04147, IPR007276): Nop14-like family PBP_sp32 (PF07222, IPR009865): Proacrosin binding protein sp32 RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4 TFIIA (PF03153, IPR004855): Transcription factor IIA, alpha/beta subunit UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain WWE (PF02825, IPR004170, SM00678): WWE domain HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54 U1snRNP70_N (PF12220, IPR022023): U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4414 (PF14377, IPR025527): Domain of unknown function (DUF4414)
72	IARS	interactor	8	0.607	9.056	Anticodon_1 (PF08264, IPR013155): Anticodon-binding domain of tRNA tRNA-synt_1 (PF00133, IPR002300): tRNA synthetases class I (I, L, M and V)
73	KHDRBS1	protein found in more fusions	13	0.409	18.372	KH_1 (PF00013, IPR004088, SM00322): KH domain Qua1 (PF16274, IPR032571): Qua1 domain Sam68-YY (PF16568, IPR032335): Tyrosine-rich domain of Sam68
74	KHSRP	interactor	5	0.600	0.767	DUF1897 (PF09005, IPR015096): Domain of unknown function (DUF1897) KH_1 (PF00013, IPR004088, SM00322): KH domain
75	KPNA1	interactor	10	0.378	15.056	Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat IBB (PF01749, IPR002652): Importin beta binding domain Arm_3 (PF16186, IPR032413): Atypical Arm repeat
76	LRPPRC	interactor	6	0.400	1.951	DED (PF01335, IPR001875, SM00031): Death effector domain MA3 (PF02847, IPR003891, SM00544): MA3 domain PPR (PF01535, IPR002885): PPR repeat TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat ApoB100_C (PF12491, IPR022176): Apolipoprotein B100 C terminal PPR_2 (PF13041, IPR002885): PPR repeat family PPR_3 (PF13812, IPR002885): Pentatricopeptide repeat domain TPR_19 (PF14559): Tetratricopeptide repeat PPR_long (PF17177): Pentacotripeptide-repeat region of PROPR
77	MAP4	oncoprotein	3	0.667	0.667	SdiA-regulated (PF06977, IPR009722): SdiA-regulated Tubulin-binding (PF00418, IPR001084): Tau and MAP protein, tubulin-binding repeat DUF3275 (PF11679, IPR021693): Protein of unknown function (DUF3275)
78	MARS	oncoprotein	8	0.786	1.800	Anticodon_1 (PF08264, IPR013155): Anticodon-binding domain of tRNA DUF16 (PF01519, IPR002862): Protein of unknown function DUF16 GST_C (PF00043, IPR004046): Glutathione S-transferase, C-terminal domain tRNA-synt_1g (PF09334, IPR015413): tRNA synthetases class I (M) WHEP-TRS (PF00458, IPR000738, SM00991): WHEP-TRS domain GST_N_2 (PF13409, IPR004045): Glutathione S-transferase, N-terminal domain
79	MATR3	interactor	19	0.405	41.250	DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-U1 (PF06220, IPR013085, SM00451): U1 zinc finger Tim54 (PF11711, IPR021056): Inner membrane protein import complex subunit Tim54 zf-C2H2_jaz (PF12171, IPR022755): Zinc-finger double-stranded RNA-binding RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FAM60A (PF15396, IPR026065): Protein Family FAM60A
80	MCM4	interactor	10	0.528	5.880	MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain
81	MCM5	oncoprotein	18	0.255	56.841	MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain
82	MCM7	protein found in more fusions	11	0.400	15.894	MCM (PF00493, IPR001208, SM00350): MCM2/3/5 family MCM_N (PF14551, IPR027925): MCM N-terminal domain MCM_OB (PF17207): MCM OB domain
83	MTHFD1	interactor	5	0.500	1.148	FTHFS (PF01268, IPR000559): Formate--tetrahydrofolate ligase THF_DHG_CYH (PF00763, IPR020630): Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C (PF02882, IPR020631): Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain
84	MTUS2	suppressor	2	0	0	DUF496 (PF04363, IPR007458): Protein of unknown function (DUF496) RNA_pol_Rpb1_R (PF05001, IPR000684): RNA polymerase Rpb1 C-terminal repeat FAM184 (PF15665): Family with sequence similarity 184, A and B
85	MYCBP2	interactor	5	0.600	2.567	ANAPC10 (PF03256, IPR004939): Anaphase-promoting complex, subunit 10 (APC10) Filamin (PF00630, IPR017868): Filamin/ABP280 repeat Peptidase_S49_N (PF08496, IPR013703): Peptidase family S49 N-terminal PHR (PF08005, IPR012983): PHR domain RCC1 (PF00415, IPR000408): Regulator of chromosome condensation (RCC1) repeat SH3_3 (PF08239, IPR003646): Bacterial SH3 domain XPA_N (PF01286, IPR022652): XPA protein N-terminal zf-B_box (PF00643, IPR000315, SM00336): B-box zinc finger zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain RCC1_2 (PF13540): Regulator of chromosome condensation (RCC1) repeat
86	NCL	protein found in more fusions	17	0.367	35.750	DUF1754 (PF08555, IPR013865): Eukaryotic family of unknown function (DUF1754) Myc_N (PF01056, IPR012682): Myc amino-terminal region RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YL1 (PF05764, IPR008895): YL1 nuclear protein Limkain-b1 (PF11608, IPR024582): Limkain b1
87	NONO	oncoprotein	9	0.429	8.608	GvpL_GvpF (PF06386, IPR009430): Gas vesicle synthesis protein GvpL/GvpF NOPS (PF08075, IPR012975): NOPS (NUC059) domain RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PAS_7 (PF12860): PAS fold SUIM_assoc (PF16619): Unstructured region C-term to UIM in Ataxin3
88	NPAS2	suppressor	6	0.800	1.433	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain PAS (PF00989, IPR013767, SM00091): PAS fold DehI (PF10778, IPR019714): Halocarboxylic acid dehydrogenase DehI PAS_11 (PF14598): PAS domain
89	NXF1	interactor	44	0.165	515.549	NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain LRR_8 (PF13855, IPR001611): Leucine rich repeat
90	NXN	interactor	1	0	0	Thioredoxin_6 (PF13848): Thioredoxin-like domain Thioredoxin_8 (PF13905, IPR012336): Thioredoxin-like
91	PAICS	interactor	7	0.667	2.567	AIRC (PF00731, IPR000031, SM01001): AIR carboxylase SAICAR_synt (PF01259, IPR028923): SAICAR synthetase
92	PCBP1	oncoprotein	11	0.564	7.992	Bac_chlorC (PF02043, IPR001470): Bacteriochlorophyll C binding protein KH_2 (PF07650, IPR004044): KH domain KH_1 (PF00013, IPR004088, SM00322): KH domain
93	PDE9A	interactor	2	0	0	PDEase_I (PF00233, IPR002073): 3'5'-cyclic nucleotide phosphodiesterase
94	PER1	oncoprotein	10	0.467	13.467	PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold SPX (PF03105, IPR004331): SPX domain SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein Period_C (PF12114, IPR022728): Period protein 2/3C-terminal region
95	PER2	suppressor	9	0.639	6.145	PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold Period_C (PF12114, IPR022728): Period protein 2/3C-terminal region
96	PER3	interactor	4	0.833	0.286	PAS (PF00989, IPR013767, SM00091): PAS fold PAS_3 (PF08447, IPR013655): PAS fold DNA_Packaging (PF11053, IPR020342): Terminase DNA packaging enzyme Period_C (PF12114, IPR022728): Period protein 2/3C-terminal region
97	PHGDH	interactor	9	0.361	8.590	2-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
98	PPP2CB	suppressor	15	0.524	29.148	Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
99	PPP2R1B	suppressor	14	0.474	23.271	HEAT (PF02985, IPR000357): HEAT repeat Cnd1 (PF12717, IPR032682): non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region HEAT_2 (PF13646): HEAT repeats
100	PPP2R2A	interactor	11	0.691	6.658	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Y_phosphatase2 (PF03162, IPR004861): Tyrosine phosphatase family ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
101	PPP2R2D	interactor	11	0.655	10.138	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat Y_phosphatase2 (PF03162, IPR004861): Tyrosine phosphatase family ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
102	PPP2R5D	interactor	9	0.667	6.186	B56 (PF01603, IPR002554): Protein phosphatase 2A regulatory B subunit (B56 family)
103	PPP2R5E	protein found in more fusions	10	0.778	2.281	B56 (PF01603, IPR002554): Protein phosphatase 2A regulatory B subunit (B56 family)
104	PPP5C	interactor	9	0.556	6.375	Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase PPP5 (PF08321, IPR013235): PPP5 TPR repeat region TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat TPR_17 (PF13431): Tetratricopeptide repeat
105	PRKDC	protein found in more fusions	14	0.359	20.756	FAT (PF02259, IPR003151): FAT domain FATC (PF02260, IPR003152): FATC domain NUC194 (PF08163, IPR012582): NUC194 domain PI3_PI4_kinase (PF00454, IPR000403, SM00146): Phosphatidylinositol 3- and 4-kinase
106	PRMT1	interactor	13	0.470	15.275	Methyltransf_25 (PF13649): Methyltransferase domain
107	PSMC2	protein found in more fusions	19	0.464	41.414	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA)
108	PSMC3	interactor	14	0.603	20.391	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) DUF3713 (PF12506, IPR022186): Protein of unknown function (DUF3713) JIP_LZII (PF16471, IPR032486): JNK-interacting protein leucine zipper II
109	PSMC4	interactor	15	0.552	23.611	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) NTPase_1 (PF03266, IPR004948): NTPase CENP-F_leu_zip (PF10473, IPR019513): Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_16 (PF13191): AAA ATPase domain
110	PSMC5	protein found in more fusions	13	0.727	6.302	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) Laminin_II (PF06009, IPR010307): Laminin Domain II RILP (PF11461, IPR021563): Rab interacting lysosomal protein AAA_16 (PF13191): AAA ATPase domain
111	PSMD1	interactor	16	0.492	29.822	PA26 (PF04636, IPR006730): PA26 p53-induced protein (sestrin) PC_rep (PF01851, IPR002015): Proteasome/cyclosome repeat HEAT_2 (PF13646): HEAT repeats
112	PSMD11	interactor	11	0.800	3.852	DUF247 (PF03140, IPR004158): Plant protein of unknown function PCI (PF01399, IPR000717, SM00088): PCI domain AAA_16 (PF13191): AAA ATPase domain TPR_12 (PF13424): Tetratricopeptide repeat
113	PSMD2	oncoprotein	13	0.654	11.407	PC_rep (PF01851, IPR002015): Proteasome/cyclosome repeat THAP (PF05485, IPR006612, SM00980): THAP domain HEAT_2 (PF13646): HEAT repeats
114	PSMD3	interactor	11	0.855	1.739	Rpn3_C (PF08375, IPR013586): Proteasome regulatory subunit C-terminal TPR_2 (PF07719, IPR013105): Tetratricopeptide repeat PCI (PF01399, IPR000717, SM00088): PCI domain Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat TSKS (PF15358, IPR028214): Testis-specific serine kinase substrate
115	QPRT	interactor	4	1.000	0	QRPTase_C (PF01729, IPR002638): Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N (PF02749, IPR022412): Quinolinate phosphoribosyl transferase, N-terminal domain
116	RAN	oncoprotein	6	0.667	2.071	Ras (PF00071, IPR001806, SM00173): Ras family
117	RANBP2	oncoprotein	20	0.345	54.153	Pro_isomerase (PF00160, IPR002130): Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat Ran_BP1 (PF00638, IPR000156, SM00160): RanBP1 domain zf-RanBP (PF00641, IPR001876, SM00547): Zn-finger in Ran binding protein and others DUF2693 (PF10902, IPR024401): Protein of unknown function (DUF2693) IR1-M (PF12185, IPR022011): Nup358/RanBP2 E3 ligase domain Dmrt1 (PF12374, IPR022114): Double-sex mab3 related transcription factor 1 TPR_9 (PF13371, IPR011990): Tetratricopeptide repeat TPR_11 (PF13414, IPR011990): TPR repeat TPR_12 (PF13424): Tetratricopeptide repeat TPR_19 (PF14559): Tetratricopeptide repeat
118	RNF219	interactor	2	1.000	0	CENP-Q (PF13094, IPR025212): CENP-Q, a CENPA-CAD centromere complex subunit zf-C3HC4_2 (PF13923): Zinc finger, C3HC4 type (RING finger) zf-RING_4 (PF14570): RING/Ubox like zinc-binding domain PRKG1_interact (PF15898, IPR031775): cGMP-dependent protein kinase interacting domain
119	RPL10	suppressor	10	0.711	2.926	Ribosomal_L16 (PF00252, IPR016180): Ribosomal protein L16p/L10e
120	RPN1	oncoprotein	10	0.444	14.171	Ribophorin_I (PF04597, IPR007676): Ribophorin I CtIP_N (PF10482, IPR019518): Tumour-suppressor protein CtIP N-terminal domain
121	RPS14	interactor	13	0.641	6.458	Ribosomal_S11 (PF00411, IPR001971): Ribosomal protein S11
122	RPS17	interactor	9	0.750	1.587	Ribosomal_S17e (PF00833, IPR001210): Ribosomal S17
123	RPS2	interactor	18	0.477	34.964	Ribosomal_S5 (PF00333, IPR013810): Ribosomal protein S5, N-terminal domain Ribosomal_S5_C (PF03719, IPR005324): Ribosomal protein S5, C-terminal domain
124	RPS3	interactor	19	0.503	27.918	KH_2 (PF07650, IPR004044): KH domain Ribosomal_S3_C (PF00189, IPR001351): Ribosomal protein S3, C-terminal domain
125	RPS6	interactor	17	0.574	16.897	Ribosomal_S6e (PF01092, IPR001377): Ribosomal protein S6e DUF4574 (PF15141, IPR027896): Domain of unknown function (DUF4574)
126	RUVBL2	oncoprotein	21	0.347	52.270	TIP49 (PF06068, IPR010339): TIP49 C-terminus
127	SDHA	suppressor	10	0.467	12.056	FAD_binding_2 (PF00890, IPR003953): FAD binding domain Succ_DH_flav_C (PF02910, IPR015939): Fumarate reductase flavoprotein C-term
128	SEC16A	interactor	7	0.619	3.219	APC_r (PF05923): APC repeat Sec16_C (PF12931, IPR024298): Sec23-binding domain of Sec16 Sec16 (PF12932, IPR024340): Vesicle coat trafficking protein Sec16 mid-region
129	SKP1	oncoprotein	12	0.545	12.590	Skp1 (PF01466, IPR016072, SM00512): Skp1 family, dimerisation domain Skp1_POZ (PF03931, IPR016073): Skp1 family, tetramerisation domain
130	SMC2	interactor	3	0.667	1.000	SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200) DUF4201 (PF13870, IPR025254): Domain of unknown function (DUF4201)
131	SMC4	interactor	2	1.000	0	SMC_N (PF02463, IPR003395): RecF/RecN/SMC N terminal domain Caskin-Pro-rich (PF16907): Proline rich region of Caskin proteins
132	SNRNP200	protein found in more fusions	13	0.439	16.460	DEAD (PF00270, IPR011545): DEAD/DEAH box helicase DUF603 (PF04645, IPR006739): Protein of unknown function, DUF603 Sec63 (PF02889, IPR004179, SM00973): Sec63 Brl domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
133	SRM	interactor	2	1.000	0	Spermine_synth (PF01564, IPR001045): Spermine/spermidine synthase
134	STK11	suppressor	6	0.467	3.697	Pkinase (PF00069, IPR000719): Protein kinase domain
135	TEKT4	interactor	4	0.667	1.222	Tektin (PF03148, IPR000435): Tektin family
136	TIMELESS	interactor	2	1.000	0	Myc_N (PF01056, IPR012682): Myc amino-terminal region TIMELESS (PF04821, IPR006906): Timeless protein TIMELESS_C (PF05029, IPR007725): Timeless protein C terminal region Myb_DNA-binding (PF00249, IPR001005, SM00717): Myb-like DNA-binding domain
137	TMPO	interactor	3	0.667	0.333	LEM (PF03020, IPR003887, SM00540): LEM domain Thymopoietin (PF08198, IPR013146): Thymopoietin protein LAP2alpha (PF11560, IPR021623): Lamina-associated polypeptide 2 alpha
138	TTC1	interactor	9	0.361	13.350	TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat Fis1_TPR_C (PF14853, IPR028061): Fis1 C-terminal tetratricopeptide repeat
139	TUFM	interactor	9	0.611	7.038	GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain GTP_EFTU_D2 (PF03144, IPR004161): Elongation factor Tu domain 2 GTP_EFTU_D3 (PF03143, IPR004160): Elongation factor Tu C-terminal domain
140	UBR5	protein found in more fusions	10	0.306	11.077	CENP-B_dimeris (PF09026, IPR015115): Centromere protein B dimerisation domain SDA1 (PF05285, IPR007949): SDA1 HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase) PABP (PF00658, IPR002004, SM00517): Poly-adenylate binding protein, unique domain E3_UbLigase_EDD (PF11547, IPR024725): E3 ubiquitin ligase EDD PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF3915 (PF13054, IPR025026): Protein of unknown function (DUF3915) RCDG1 (PF15725, IPR031457): Renal cancer differentiation gene 1 protein
141	USP11	protein found in more fusions	10	0.444	10.880	Ribosomal_60s (PF00428, IPR001813): 60s Acidic ribosomal protein UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase DUSP (PF06337, IPR006615, SM00695): DUSP domain Ubiquitin_3 (PF14836, IPR028135): Ubiquitin-like domain
142	USP7	oncoprotein	19	0.248	79.625	MATH (PF00917, IPR002083, SM00061): MATH domain UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg (PF12436, IPR024729): ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 (PF14533, IPR029346): Ubiquitin-specific protease C-terminal
143	USP9X	interactor	11	0.436	20.251	DUF1722 (PF08349, IPR013560): Protein of unknown function (DUF1722) UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase Utp13 (PF08625, IPR013934): Utp13 specific WD40 associated domain
144	VCP	protein found in more fusions	37	0.244	268.045	AAA (PF00004, IPR003959, SM00382): ATPase family associated with various cellular activities (AAA) CDC48_2 (PF02933, IPR004201, SM01072): Cell division protein 48 (CDC48), domain 2 CDC48_N (PF02359, IPR003338, SM01073): Cell division protein 48 (CDC48), N-terminal domain TniB (PF05621, IPR008868): Bacterial TniB protein Vps4_C (PF09336, IPR015415): Vps4 C terminal oligomerisation domain DUF3944 (PF13099, IPR025217): Domain of unknown function (DUF3944)
145	XPO1	interactor	41	0.173	437.602	CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain Xpo1 (PF08389, IPR013598): Exportin 1-like protein Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
146	XRCC6	oncoprotein	11	0.400	11.262	Ku (PF02735, IPR006164, SM00559): Ku70/Ku80 beta-barrel domain Ku_C (PF03730, IPR005160): Ku70/Ku80 C-terminal arm Ku_N (PF03731, IPR005161): Ku70/Ku80 N-terminal alpha/beta domain SAP (PF02037, IPR003034, SM00513): SAP domain
147	XRN2	interactor	7	0.714	1.238	XRN_N (PF03159, IPR004859): XRN 5'-3' exonuclease N-terminus
148	YWHAE	oncoprotein	18	0.431	38.740	14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
149	YWHAQ	interactor	19	0.263	69.344	14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein

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