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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)102
The number (and %) of the onco-proteins26 (25.49 %)
The number (and %) of the tumor suppressors19 (18.63 %)
Total number of binary PPIs (saturation %)383 (7.44 %)
The number (and %) of affected PPIs104 (27.15 %)
The number of possible different fusions21
PPI diameter4
PPI radius2
The average degree of PPI6.725
Assortativity coefficient-0.1697
The network average Clustering coefficient0.382
The number (and %) of a zero Clustering coefficients22 (21.57 %)
The number (and %) of a zero Betweenness Centrality29 (28.43 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: DYRK1A,COL1A1 All fusions
Proteins found in more fusions CREBBP (see 6 fusions); CTBP1 (see 2 fusions); COL1A1/COL1A2 (see 1 fusions); APP (see 5 fusions); COL1A1/PDGFB (see 20 fusions); YWHAG (see 1 fusions); PKD1 (see 1 fusions); SH3GL2 (see 1 fusions); NID1 (see 1 fusions); SRSF1 (see 1 fusions); HIPK2 (see 1 fusions); SFN (see 1 fusions); TROAP (see 1 fusions); EP300 (see 1 fusions); MAP3K5 (see 1 fusions); UBC (see 7 fusions); COL1A1 (see 14 fusions); MAP3K1 (see 1 fusions); PARK2 (see 1 fusions); SMAD3 (see 3 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 DYRK1Aparental protein680.0794658.233DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755)
Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region
Pkinase (PF00069, IPR000719): Protein kinase domain
FAM199X (PF15814, IPR029672): Protein family FAM199X
2 COL1A1parental protein360.0353291.651COLFI (PF01410, IPR000885, SM00038): Fibrillar collagen C-terminal domain
Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
VWC (PF00093, IPR001007, SM00214): von Willebrand factor type C domain
EKLF_TAD1 (PF16832, IPR031786): Erythroid krueppel-like transcription factor, transactivation 1
3 ABCD3interactor40.6671.550ABC_membrane_2 (PF06472, IPR010509): ABC transporter transmembrane region 2
ABC_tran (PF00005, IPR003439): ABC transporter
4 AMPHoncoprotein50.40010.819BAR (PF03114, IPR004148, SM00721): BAR domain
SH3_9 (PF14604, IPR001452): Variant SH3 domain
PBP_N (PF17093, IPR031375): Penicillin-binding protein N-terminus
5 APPprotein found in more fusions150.154267.067APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding
Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP)
BUD22 (PF09073, IPR015158): BUD22
IncA (PF04156, IPR007285): IncA protein
Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus
APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD
APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
6 ATP13A2interactor2036.990E1-E2_ATPase (PF00122, IPR008250): E1-E2 ATPase
Hydrolase (PF00702, IPR023214): haloacid dehalogenase-like hydrolase
MARVEL (PF01284, IPR008253): Membrane-associating domain
P5-ATPase (PF12409, IPR006544): P5-type ATPase cation transporter
7 BARD1suppressor120.309510.467BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
Ank_5 (PF13857): Ankyrin repeats (many copies)
zf-RING_6 (PF14835): zf-RING of BARD1-type protein
BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain
8 BRCA1suppressor150.231400.019BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain
zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT
9 C12orf57interactor100P_C10 (PF14974, IPR026317): Protein C10
10 CAMKMTinteractor50.20088.741Methyltransf_16 (PF10294, IPR019410): Lysine methyltransferase
11 CAPN1interactor3073.575Calpain_III (PF01067, IPR022682, SM00720): Calpain large subunit, domain III
Peptidase_C2 (PF00648, IPR001300, SM00230): Calpain family cysteine protease
EF-hand_6 (PF13405, IPR002048): EF-hand domain
EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
12 CCDC8interactor100.361167.702Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein
SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal
PNMA (PF14893, IPR026523): PNMA
13 CCNA2oncoprotein80.6196.899Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain
Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
Cyclin_N2 (PF16500, IPR032447): N-terminal region of cyclin_N
14 CCNL2interactor21.0000Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain
Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
15 CD200R1interactor100C2-set_2 (PF08205, IPR013162): CD80-like C2-set immunoglobulin domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Fig1 (PF12351): Ca2+ regulator and membrane fusion protein Fig1
16 CLASRPinteractor40.5001.567Corona_nucleoca (PF00937, IPR001218): Coronavirus nucleocapsid protein
OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain
Pap_E4 (PF02711, IPR003861): E4 protein
RAP1 (PF07218, IPR009864): Rhoptry-associated protein 1 (RAP-1)
S-antigen (PF05756, IPR008825): S-antigen protein
Transformer (PF06495, IPR010519): Fruit fly transformer protein
DRY_EERY (PF09750, IPR019147, SM01141): Alternative splicing regulator
LRRFIP (PF09738, IPR019139): LRRFIP family
DUF4554 (PF15091, IPR028040): Domain of unknown function (DUF4554)
17 CLTConcoprotein100.22241.263Clathrin-link (PF09268, IPR015348): Clathrin, heavy-chain linker
Clathrin_propel (PF01394, IPR022365): Clathrin propeller repeat
Clathrin (PF00637, IPR000547, SM00299): Region in Clathrin and VPS
Clathrin_H_link (PF13838): Clathrin-H-link
18 COL1A2oncoprotein50.40010.020COLFI (PF01410, IPR000885, SM00038): Fibrillar collagen C-terminal domain
Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
DUF1860 (PF08949, IPR015044): Domain of unknown function (DUF1860)
19 COL7A1oncoprotein50.10075.385Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies)
DUF1860 (PF08949, IPR015044): Domain of unknown function (DUF1860)
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain
VWA (PF00092, IPR002035, SM00327): von Willebrand factor type A domain
DUF4249 (PF14054, IPR025345): Domain of unknown function (DUF4249)
DUF4992 (PF16383, IPR032155): Domain of unknown function
20 CREBBPsuppressor150.38581.391Creb_binding (PF09030, IPR014744): Creb binding
DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902)
Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
KIX (PF02172, IPR003101): KIX domain
MAS20 (PF02064, IPR002056): MAS20 protein import receptor
TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2)
zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger
ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26
HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729)
DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834)
21 CTBP1protein found in more fusions110.60017.8012-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
Cellsynth_D (PF03500, IPR022798): Cellulose synthase subunit D
22 DCAF7interactor160.217216.779WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
23 DNM1interactor60.50057.483Dynamin_M (PF01031, IPR000375): Dynamin central region
GED (PF02212, IPR003130, SM00302): Dynamin GTPase effector domain
PH (PF00169, IPR001849, SM00233): PH domain
Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family
24 DNM3interactor30.33379.896Dynamin_M (PF01031, IPR000375): Dynamin central region
GED (PF02212, IPR003130, SM00302): Dynamin GTPase effector domain
PH (PF00169, IPR001849, SM00233): PH domain
Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family
25 DYNLL1interactor80.33314.842Dynein_light (PF01221, IPR001372): Dynein light chain type 1
26 DYNLL2interactor31.0000Dynein_light (PF01221, IPR001372): Dynein light chain type 1
27 EGLN2interactor2002OG-FeII_Oxy_3 (PF13640, IPR005123): 2OG-Fe(II) oxygenase superfamily
28 ELAVL1oncoprotein260.1671358.326RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
29 EP300oncoprotein170.32599.620Creb_binding (PF09030, IPR014744): Creb binding
DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902)
Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
KIX (PF02172, IPR003101): KIX domain
RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6
TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2)
zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger
HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
30 ERAL1interactor30.33321.833GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain
MMR_HSR1 (PF01926, IPR006073): 50S ribosome-binding GTPase
KH_1 (PF00013, IPR004088, SM00322): KH domain
31 FAM117Aoncoprotein100FAM117 (PF15388, IPR026642): Protein Family FAM117
32 FAM117Binteractor40.50014.781FAM117 (PF15388, IPR026642): Protein Family FAM117
PRIMA1 (PF16101): Proline-rich membrane anchor 1
33 FAM53Cinteractor60.4676.752FAM53 (PF15242, IPR029356): Family of FAM53
34 FNTAinteractor21.0000CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
PPTA (PF01239, IPR002088): Protein prenyltransferase alpha subunit repeat
TPR_14 (PF13428): Tetratricopeptide repeat
DUF4219 (PF13961, IPR025314): Domain of unknown function (DUF4219)
35 FNTBinteractor60.26755.521Prenyltrans (PF00432, IPR001330): Prenyltransferase and squalene oxidase repeat
36 FOXR2interactor100Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
37 GIPC2interactor200PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
38 GLCCI1interactor30.6670.500Herpes_LMP2 (PF07415, IPR010881): Gammaherpesvirus latent membrane protein (LMP2) protein
Pap_E4 (PF02711, IPR003861): E4 protein
DUF2076 (PF09849, IPR018648): Uncharacterized protein conserved in bacteria (DUF2076)
FAM117 (PF15388, IPR026642): Protein Family FAM117
39 HIPK2suppressor70.6673.500Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family
Pkinase (PF00069, IPR000719): Protein kinase domain
40 HIST1H2BBinteractor70.57111.578Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
41 HIST1H3Ainteractor90.46418.898Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
42 HIST1H4Ainteractor51.0000CENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold
43 ID2oncoprotein50.6670.833HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
44 IGFBP3suppressor100IGFBP (PF00219, IPR000867, SM00121): Insulin-like growth factor binding protein
Thyroglobulin_1 (PF00086, IPR000716, SM00211): Thyroglobulin type-1 repeat
45 ISG15suppressor40.5005.990ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
46 ITGA2interactor21.0000FG-GAP (PF01839, IPR013517): FG-GAP repeat
Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region
Integrin_alpha2 (PF08441, IPR013649): Integrin alpha
VWA (PF00092, IPR002035, SM00327): von Willebrand factor type A domain
VCBS (PF13517): Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella
FG-GAP_2 (PF14312, IPR013517): FG-GAP repeat
47 ITGB1suppressor70.381138.645EGF_2 (PF07974, IPR013111): EGF-like domain
Integrin_b_cyt (PF08725, IPR014836): Integrin beta cytoplasmic domain
Integrin_B_tail (PF07965, IPR012896): Integrin beta tail domain
Integrin_beta (PF00362, IPR002369, SM00187): Integrin beta chain VWA domain
PSI_integrin (PF17205): Integrin plexin domain
48 KIAA0232interactor100DUF4603 (PF15376, IPR027871): Domain of unknown function (DUF4603)
49 LATS2suppressor70.53332.623Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
50 LIN52interactor21.0000LIN52 (PF10044, IPR018737): Retinal tissue protein
51 LIPHinteractor100Lipase (PF00151, IPR013818): Lipase
52 LZTS2suppressor40.6671.400CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
DUF1127 (PF06568, IPR009506): Domain of unknown function (DUF1127)
Fez1 (PF06818): Fez1
ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding
DUF4250 (PF14056, IPR025346): Domain of unknown function (DUF4250)
53 MAGinteractor2015.649C2-set_2 (PF08205, IPR013162): CD80-like C2-set immunoglobulin domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
54 MAP3K1oncoprotein80.52417.901zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding
Pkinase (PF00069, IPR000719): Protein kinase domain
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
Phostensin_N (PF13916, IPR025903): PP1-regulatory protein, Phostensin N-terminal
55 MAP3K5oncoprotein70.33333.956Pkinase (PF00069, IPR000719): Protein kinase domain
DUF4071 (PF13281, IPR025136): Domain of unknown function (DUF4071)
56 MATN2interactor200VWA (PF00092, IPR002035, SM00327): von Willebrand factor type A domain
Matrilin_ccoil (PF10393, IPR019466): Trimeric coiled-coil oligomerisation domain of matrilin
FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site
57 MED23interactor80.60711.974Med23 (PF11573, IPR021629): Mediator complex subunit 23
58 MFSD13Ainteractor30.33316.491MFS_2 (PF13347): MFS/sugar transport protein
59 MMP2oncoprotein31.0000Peptidase_M10 (PF00413, IPR001818): Matrixin
PG_binding_1 (PF01471, IPR002477): Putative peptidoglycan binding domain
Hemopexin (PF00045, IPR018487, SM00120): Hemopexin
60 MOV10interactor90.38964.342AAA_12 (PF13087): AAA domain
AAA_30 (PF13604): AAA domain
61 NID1protein found in more fusions200EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain
G2F (PF07474, IPR006605, SM00682): G2F domain
NIDO (PF06119, IPR003886, SM00539): Nidogen-like
Ldl_recept_b (PF00058, IPR000033, SM00135): Low-density lipoprotein receptor repeat class B
Thyroglobulin_1 (PF00086, IPR000716, SM00211): Thyroglobulin type-1 repeat
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
EGF_3 (PF12947, IPR024731): EGF domain
FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site
62 NID2interactor100EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain
G2F (PF07474, IPR006605, SM00682): G2F domain
NIDO (PF06119, IPR003886, SM00539): Nidogen-like
SGL (PF08450, IPR013658): SMP-30/Gluconolaconase/LRE-like region
Ldl_recept_b (PF00058, IPR000033, SM00135): Low-density lipoprotein receptor repeat class B
Thyroglobulin_1 (PF00086, IPR000716, SM00211): Thyroglobulin type-1 repeat
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
EGF_3 (PF12947, IPR024731): EGF domain
63 NTRK1oncoprotein240.174577.481I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
64 NXF1interactor110.200155.816NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain
Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding
TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain
LRR_8 (PF13855, IPR001611): Leucine rich repeat
65 OTUB1interactor60.26795.222Peptidase_C65 (PF10275, IPR019400): Peptidase C65 Otubain
66 PARK2suppressor80.42933.897IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
67 PDGFAoncoprotein21.0000PDGF (PF00341, IPR000072, SM00141): PDGF/VEGF domain
PDGF_N (PF04692, IPR006782): Platelet-derived growth factor, N terminal region
SyrA (PF11089, IPR024239): Exopolysaccharide production repressor
68 PDGFBoncoprotein50.5003.000PDGF (PF00341, IPR000072, SM00141): PDGF/VEGF domain
PDGF_N (PF04692, IPR006782): Platelet-derived growth factor, N terminal region
69 PKD1suppressor200Stress-antifung (PF01657, IPR002902): Salt stress response/antifungal
LRRCT (PF01463, IPR000483, SM00082): Leucine rich repeat C-terminal domain
LRRNT (PF01462, IPR000372, SM00013): Leucine rich repeat N-terminal domain
PKD (PF00801, IPR000601, SM00089): PKD domain
PKD_channel (PF08016, IPR013122): Polycystin cation channel
PLAT (PF01477, IPR001024, SM00308): PLAT/LH2 domain
REJ (PF02010, IPR002859): REJ domain
WSC (PF01822, IPR002889, SM00321): WSC domain
Lectin_C (PF00059, IPR001304, SM00034): Lectin C-type domain
LRR_8 (PF13855, IPR001611): Leucine rich repeat
fn3_3 (PF14686, IPR029413): Polysaccharide lyase family 4, domain II
70 PPP1R3Finteractor100CBM_21 (PF03370, IPR005036): Carbohydrate/starch-binding module (family 21)
K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
71 PRDinteractor100NA
72 PRELPinteractor100LRRNT (PF01462, IPR000372, SM00013): Leucine rich repeat N-terminal domain
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
73 PRKACAinteractor90.44418.854Pkinase (PF00069, IPR000719): Protein kinase domain
74 PRKACBinteractor80.50022.542Pkinase (PF00069, IPR000719): Protein kinase domain
75 PRKAR1Asuppressor80.57121.850RIIa (PF02197, IPR003117, SM00394): Regulatory subunit of type II PKA R-subunit
cNMP_binding (PF00027, IPR000595, SM00100): Cyclic nucleotide-binding domain
76 RAD54L2interactor21.0000SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
FAM176 (PF14851): FAM176 family
ERCC3_RAD25_C (PF16203, IPR032438): ERCC3/RAD25/XPB C-terminal helicase
77 RB1suppressor100.42249.422RB_A (PF01858, IPR002720): Retinoblastoma-associated protein A domain
RB_B (PF01857, IPR002719): Retinoblastoma-associated protein B domain
Rb_C (PF08934, IPR015030): Rb C-terminal domain
DUF3452 (PF11934, IPR024599): Domain of unknown function (DUF3452)
DUF4592 (PF15262, IPR028030): Domain of unknown function (DUF4592)
78 RBL1suppressor80.46424.824RB_A (PF01858, IPR002720): Retinoblastoma-associated protein A domain
RB_B (PF01857, IPR002719): Retinoblastoma-associated protein B domain
Rb_C (PF08934, IPR015030): Rb C-terminal domain
DUF3452 (PF11934, IPR024599): Domain of unknown function (DUF3452)
79 RBL2suppressor70.42952.651CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal
Pap_E4 (PF02711, IPR003861): E4 protein
RB_A (PF01858, IPR002720): Retinoblastoma-associated protein A domain
RB_B (PF01857, IPR002719): Retinoblastoma-associated protein B domain
SLH (PF00395, IPR001119): S-layer homology domain
TFIIB (PF00382, IPR013150): Transcription factor TFIIB repeat
DUF3452 (PF11934, IPR024599): Domain of unknown function (DUF3452)
80 RFPL2interactor21.0000SPRY (PF00622, IPR003877, SM00449): SPRY domain
PRY (PF13765, IPR006574, SM00589): SPRY-associated domain
RDM (PF11002, IPR022723): RFPL defining motif (RDM)
zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
81 RNF169interactor40.3338.323IncA (PF04156, IPR007285): IncA protein
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
82 RNH1suppressor2011.805LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
Metallothio_Euk (PF12749, IPR024306): Eukaryotic metallothionein
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_6 (PF13516, IPR001611): Leucine Rich repeat
83 SFNsuppressor110.31139.17714-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
84 SH3GL2oncoprotein60.50054.686BAR (PF03114, IPR004148, SM00721): BAR domain
SH3_2 (PF07653, IPR011511): Variant SH3 domain
85 SIPA1L1interactor40.6671.500PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
Rap_GAP (PF02145, IPR000331): Rap/ran-GAP
SPAR_C (PF11881, IPR021818): C-terminal domain of SPAR protein
DUF4164 (PF13747, IPR025310): Domain of unknown function (DUF4164)
IQCJ-SCHIP1 (PF15157, IPR029362): Fusion protein IQCJ-SCHIP1 with IQ-like motif
86 SMAD3oncoprotein100.38953.938MH1 (PF03165, IPR003619, SM00523): MH1 domain
MH2 (PF03166, IPR001132, SM00524): MH2 domain
87 SNCAinteractor90.25077.705Synuclein (PF01387, IPR001058): Synuclein
88 SPARCsuppressor21.0000FOLN (PF09289, IPR015369, SM00274): Follistatin/Osteonectin-like EGF domain
Kazal_1 (PF00050, IPR002350): Kazal-type serine protease inhibitor domain
SPARC_Ca_bdg (PF10591, IPR019577): Secreted protein acidic and rich in cysteine Ca binding region
89 SRSF1protein found in more fusions150.37467.314Corona_nucleoca (PF00937, IPR001218): Coronavirus nucleocapsid protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
90 SRSF4interactor50.6004.800Corona_nucleoca (PF00937, IPR001218): Coronavirus nucleocapsid protein
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
91 SRSF5interactor70.8102.001DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777)
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
92 TBPinteractor70.8003.128TBP (PF00352, IPR000814): Transcription factor TFIID (or TATA-binding protein, TBP)
EPL1 (PF10513, IPR019542): Enhancer of polycomb-like
Med3 (PF11593, IPR020998): Mediator complex subunit 3 fungal
93 THBS1suppressor60.46759.248EGF (PF00008, IPR000742, SM00181): EGF-like domain
EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain
TSP_3 (PF02412, IPR003367): Thrombospondin type 3 repeat
TSP_C (PF05735, IPR008859): Thrombospondin C-terminal region
VWC (PF00093, IPR001007, SM00214): von Willebrand factor type C domain
EndIII_4Fe-2S (PF10576, IPR003651): Iron-sulfur binding domain of endonuclease III
TSP_1 (PF00090, IPR000884, SM00209): Thrombospondin type 1 domain
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
EGF_3 (PF12947, IPR024731): EGF domain
Laminin_G_3 (PF13385): Concanavalin A-like lectin/glucanases superfamily
94 TMTC4interactor30.33315.992DUF1736 (PF08409, IPR013618): Domain of unknown function (DUF1736)
TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat
DUF3382 (PF11862, IPR021807): Domain of unknown function (DUF3382)
TPR_12 (PF13424): Tetratricopeptide repeat
TPR_14 (PF13428): Tetratricopeptide repeat
TPR_17 (PF13431): Tetratricopeptide repeat
TPR_16 (PF13432): Tetratricopeptide repeat
DUF4131 (PF13567, IPR025405): Domain of unknown function (DUF4131)
95 TRAF3oncoprotein70.26734.013ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16)
S-AdoMet_synt_M (PF02772, IPR022629): S-adenosylmethionine synthetase, central domain
zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger)
zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger
zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain
MPS2 (PF17060, IPR031433): Monopolar spindle protein 2
Spc29 (PF17082, IPR031392): Spindle Pole Component 29
96 TROAPprotein found in more fusions60.40011.173Strep_pep (PF14404, IPR025744): Ribosomally synthesized peptide in Streptomyces species
97 TXNoncoprotein50.20070.583Thioredoxin (PF00085, IPR013766): Thioredoxin
98 UBCprotein found in more fusions160.143343.118ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
99 UBXN11interactor100DivIC (PF04977, IPR007060): Septum formation initiator
SEP (PF08059, IPR012989, SM00553): SEP domain
UBX (PF00789, IPR001012, SM00166): UBX domain
DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200)
TRPM_tetra (PF16519, IPR032415): Tetramerisation domain of TRPM
100 VWFinteractor100Antistasin (PF02822, IPR004094): Antistasin family
C8 (PF08742, IPR014853, SM00832): C8 domain
Metallothio_5 (PF02067, IPR000966): Metallothionein family 5
Pacifastin_I (PF05375, IPR008037): Pacifastin inhibitor (LCMII)
TIL (PF01826, IPR002919): Trypsin Inhibitor like cysteine rich domain
VWA (PF00092, IPR002035, SM00327): von Willebrand factor type A domain
VWC (PF00093, IPR001007, SM00214): von Willebrand factor type C domain
VWD (PF00094, IPR001846, SM00216): von Willebrand factor type D domain
VWA_N2 (PF16164, IPR032361): VWA N-terminal
101 XPO1interactor170.301150.423CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal
Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase
IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain
Xpo1 (PF08389, IPR013598): Exportin 1-like protein
Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
102 YWHAGprotein found in more fusions140.37278.26114-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein

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