Statistic of PPI	Value(s)
The number of interactors (fusion and proteins)	102
The number (and %) of the onco-proteins	26 (25.49 %)
The number (and %) of the tumor suppressors	19 (18.63 %)
Total number of binary PPIs (saturation %)	383 (7.44 %)
The number (and %) of affected PPIs	104 (27.15 %)
The number of possible different fusions	21
PPI diameter	4
PPI radius	2
The average degree of PPI	6.725
Assortativity coefficient	-0.1697
The network average Clustering coefficient	0.382
The number (and %) of a zero Clustering coefficients	22 (21.57 %)
The number (and %) of a zero Betweenness Centrality	29 (28.43 %)

ACTIVE INTERACTORS

List of the fusions
PPI for parental proteins: DYRK1A,COL1A1	All fusions
Proteins found in more fusions	CREBBP (see 6 fusions); CTBP1 (see 2 fusions); COL1A1/COL1A2 (see 1 fusions); APP (see 5 fusions); COL1A1/PDGFB (see 20 fusions); YWHAG (see 1 fusions); PKD1 (see 1 fusions); SH3GL2 (see 1 fusions); NID1 (see 1 fusions); SRSF1 (see 1 fusions); HIPK2 (see 1 fusions); SFN (see 1 fusions); TROAP (see 1 fusions); EP300 (see 1 fusions); MAP3K5 (see 1 fusions); UBC (see 7 fusions); COL1A1 (see 14 fusions); MAP3K1 (see 1 fusions); PARK2 (see 1 fusions); SMAD3 (see 3 fusions);

List of the fusions

PPI for parental proteins: DYRK1A,COL1A1

All fusions

Proteins found in more fusions

CREBBP (see 6 fusions); CTBP1 (see 2 fusions); COL1A1/COL1A2 (see 1 fusions); APP (see 5 fusions); COL1A1/PDGFB (see 20 fusions); YWHAG (see 1 fusions); PKD1 (see 1 fusions); SH3GL2 (see 1 fusions); NID1 (see 1 fusions); SRSF1 (see 1 fusions); HIPK2 (see 1 fusions); SFN (see 1 fusions); TROAP (see 1 fusions); EP300 (see 1 fusions); MAP3K5 (see 1 fusions); UBC (see 7 fusions); COL1A1 (see 14 fusions); MAP3K1 (see 1 fusions); PARK2 (see 1 fusions); SMAD3 (see 3 fusions);

List of active interactors

#	Name	Type	Number of PPI (degree)	Clustering Coefficient	Betweenness Centrality	Domains (Pfam, InterPro, SMART): description
1	DYRK1A	parental protein	68	0.079	4658.233	DUF755 (PF05501, IPR008474): Domain of unknown function (DUF755) Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region Pkinase (PF00069, IPR000719): Protein kinase domain FAM199X (PF15814, IPR029672): Protein family FAM199X
2	COL1A1	parental protein	36	0.035	3291.651	COLFI (PF01410, IPR000885, SM00038): Fibrillar collagen C-terminal domain Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies) VWC (PF00093, IPR001007, SM00214): von Willebrand factor type C domain EKLF_TAD1 (PF16832, IPR031786): Erythroid krueppel-like transcription factor, transactivation 1
3	ABCD3	interactor	4	0.667	1.550	ABC_membrane_2 (PF06472, IPR010509): ABC transporter transmembrane region 2 ABC_tran (PF00005, IPR003439): ABC transporter
4	AMPH	oncoprotein	5	0.400	10.819	BAR (PF03114, IPR004148, SM00721): BAR domain SH3_9 (PF14604, IPR001452): Variant SH3 domain PBP_N (PF17093, IPR031375): Penicillin-binding protein N-terminus
5	APP	protein found in more fusions	15	0.154	267.067	APP_N (PF02177, IPR015849, SM00006): Amyloid A4 N-terminal heparin-binding Beta-APP (PF03494, IPR013803): Beta-amyloid peptide (beta-APP) BUD22 (PF09073, IPR015158): BUD22 IncA (PF04156, IPR007285): IncA protein Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain APP_amyloid (PF10515, IPR019543): beta-amyloid precursor protein C-terminus APP_Cu_bd (PF12924, IPR011178): Copper-binding of amyloid precursor, CuBD APP_E2 (PF12925, IPR024329): E2 domain of amyloid precursor protein
6	ATP13A2	interactor	2	0	36.990	E1-E2_ATPase (PF00122, IPR008250): E1-E2 ATPase Hydrolase (PF00702, IPR023214): haloacid dehalogenase-like hydrolase MARVEL (PF01284, IPR008253): Membrane-associating domain P5-ATPase (PF12409, IPR006544): P5-type ATPase cation transporter
7	BARD1	suppressor	12	0.309	510.467	BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies) Ank_5 (PF13857): Ankyrin repeats (many copies) zf-RING_6 (PF14835): zf-RING of BARD1-type protein BRCT_2 (PF16589, IPR001357): BRCT domain, a BRCA1 C-terminus domain
8	BRCA1	suppressor	15	0.231	400.019	BRCT (PF00533, IPR001357, SM00292): BRCA1 C Terminus (BRCT) domain zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) BRCT_assoc (PF12820, IPR025994): Serine-rich domain associated with BRCT
9	C12orf57	interactor	1	0	0	P_C10 (PF14974, IPR026317): Protein C10
10	CAMKMT	interactor	5	0.200	88.741	Methyltransf_16 (PF10294, IPR019410): Lysine methyltransferase
11	CAPN1	interactor	3	0	73.575	Calpain_III (PF01067, IPR022682, SM00720): Calpain large subunit, domain III Peptidase_C2 (PF00648, IPR001300, SM00230): Calpain family cysteine protease EF-hand_6 (PF13405, IPR002048): EF-hand domain EF-hand_8 (PF13833, IPR002048): EF-hand domain pair
12	CCDC8	interactor	10	0.361	167.702	Borrelia_P83 (PF05262, IPR007926): Borrelia P83/100 protein SRP-alpha_N (PF04086, IPR007222): Signal recognition particle, alpha subunit, N-terminal PNMA (PF14893, IPR026523): PNMA
13	CCNA2	oncoprotein	8	0.619	6.899	Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain Cyclin_N2 (PF16500, IPR032447): N-terminal region of cyclin_N
14	CCNL2	interactor	2	1.000	0	Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
15	CD200R1	interactor	1	0	0	C2-set_2 (PF08205, IPR013162): CD80-like C2-set immunoglobulin domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Fig1 (PF12351): Ca2+ regulator and membrane fusion protein Fig1
16	CLASRP	interactor	4	0.500	1.567	Corona_nucleoca (PF00937, IPR001218): Coronavirus nucleocapsid protein OAD_gamma (PF04277, IPR005899): Oxaloacetate decarboxylase, gamma chain Pap_E4 (PF02711, IPR003861): E4 protein RAP1 (PF07218, IPR009864): Rhoptry-associated protein 1 (RAP-1) S-antigen (PF05756, IPR008825): S-antigen protein Transformer (PF06495, IPR010519): Fruit fly transformer protein DRY_EERY (PF09750, IPR019147, SM01141): Alternative splicing regulator LRRFIP (PF09738, IPR019139): LRRFIP family DUF4554 (PF15091, IPR028040): Domain of unknown function (DUF4554)
17	CLTC	oncoprotein	10	0.222	41.263	Clathrin-link (PF09268, IPR015348): Clathrin, heavy-chain linker Clathrin_propel (PF01394, IPR022365): Clathrin propeller repeat Clathrin (PF00637, IPR000547, SM00299): Region in Clathrin and VPS Clathrin_H_link (PF13838): Clathrin-H-link
18	COL1A2	oncoprotein	5	0.400	10.020	COLFI (PF01410, IPR000885, SM00038): Fibrillar collagen C-terminal domain Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies) DUF1860 (PF08949, IPR015044): Domain of unknown function (DUF1860)
19	COL7A1	oncoprotein	5	0.100	75.385	Collagen (PF01391, IPR008160): Collagen triple helix repeat (20 copies) DUF1860 (PF08949, IPR015044): Domain of unknown function (DUF1860) fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain Kunitz_BPTI (PF00014, IPR002223, SM00131): Kunitz/Bovine pancreatic trypsin inhibitor domain VWA (PF00092, IPR002035, SM00327): von Willebrand factor type A domain DUF4249 (PF14054, IPR025345): Domain of unknown function (DUF4249) DUF4992 (PF16383, IPR032155): Domain of unknown function
20	CREBBP	suppressor	15	0.385	81.391	Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain MAS20 (PF02064, IPR002056): MAS20 protein import receptor TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26 HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729) DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834)
21	CTBP1	protein found in more fusions	11	0.600	17.801	2-Hacid_dh_C (PF02826, IPR006140): D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Cellsynth_D (PF03500, IPR022798): Cellulose synthase subunit D
22	DCAF7	interactor	16	0.217	216.779	WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
23	DNM1	interactor	6	0.500	57.483	Dynamin_M (PF01031, IPR000375): Dynamin central region GED (PF02212, IPR003130, SM00302): Dynamin GTPase effector domain PH (PF00169, IPR001849, SM00233): PH domain Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family
24	DNM3	interactor	3	0.333	79.896	Dynamin_M (PF01031, IPR000375): Dynamin central region GED (PF02212, IPR003130, SM00302): Dynamin GTPase effector domain PH (PF00169, IPR001849, SM00233): PH domain Dynamin_N (PF00350, IPR001401, SM00053): Dynamin family
25	DYNLL1	interactor	8	0.333	14.842	Dynein_light (PF01221, IPR001372): Dynein light chain type 1
26	DYNLL2	interactor	3	1.000	0	Dynein_light (PF01221, IPR001372): Dynein light chain type 1
27	EGLN2	interactor	2	0	0	2OG-FeII_Oxy_3 (PF13640, IPR005123): 2OG-Fe(II) oxygenase superfamily
28	ELAVL1	oncoprotein	26	0.167	1358.326	RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
29	EP300	oncoprotein	17	0.325	99.620	Creb_binding (PF09030, IPR014744): Creb binding DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902) Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region KIX (PF02172, IPR003101): KIX domain RR_TM4-6 (PF06459, IPR009460): Ryanodine Receptor TM 4-6 TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2) zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein Bromodomain (PF00439, IPR001487, SM00297): Bromodomain ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
30	ERAL1	interactor	3	0.333	21.833	GTP_EFTU (PF00009, IPR000795): Elongation factor Tu GTP binding domain MMR_HSR1 (PF01926, IPR006073): 50S ribosome-binding GTPase KH_1 (PF00013, IPR004088, SM00322): KH domain
31	FAM117A	oncoprotein	1	0	0	FAM117 (PF15388, IPR026642): Protein Family FAM117
32	FAM117B	interactor	4	0.500	14.781	FAM117 (PF15388, IPR026642): Protein Family FAM117 PRIMA1 (PF16101): Proline-rich membrane anchor 1
33	FAM53C	interactor	6	0.467	6.752	FAM53 (PF15242, IPR029356): Family of FAM53
34	FNTA	interactor	2	1.000	0	CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal PPTA (PF01239, IPR002088): Protein prenyltransferase alpha subunit repeat TPR_14 (PF13428): Tetratricopeptide repeat DUF4219 (PF13961, IPR025314): Domain of unknown function (DUF4219)
35	FNTB	interactor	6	0.267	55.521	Prenyltrans (PF00432, IPR001330): Prenyltransferase and squalene oxidase repeat
36	FOXR2	interactor	1	0	0	Forkhead (PF00250, IPR001766, SM00339): Forkhead domain
37	GIPC2	interactor	2	0	0	PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
38	GLCCI1	interactor	3	0.667	0.500	Herpes_LMP2 (PF07415, IPR010881): Gammaherpesvirus latent membrane protein (LMP2) protein Pap_E4 (PF02711, IPR003861): E4 protein DUF2076 (PF09849, IPR018648): Uncharacterized protein conserved in bacteria (DUF2076) FAM117 (PF15388, IPR026642): Protein Family FAM117
39	HIPK2	suppressor	7	0.667	3.500	Kdo (PF06293, IPR010440): Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase (PF00069, IPR000719): Protein kinase domain
40	HIST1H2BB	interactor	7	0.571	11.578	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
41	HIST1H3A	interactor	9	0.464	18.898	Histone (PF00125, IPR007125): Core histone H2A/H2B/H3/H4
42	HIST1H4A	interactor	5	1.000	0	CENP-T_C (PF15511): Centromere kinetochore component CENP-T histone fold
43	ID2	oncoprotein	5	0.667	0.833	HLH (PF00010, IPR011598, SM00353): Helix-loop-helix DNA-binding domain
44	IGFBP3	suppressor	1	0	0	IGFBP (PF00219, IPR000867, SM00121): Insulin-like growth factor binding protein Thyroglobulin_1 (PF00086, IPR000716, SM00211): Thyroglobulin type-1 repeat
45	ISG15	suppressor	4	0.500	5.990	ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
46	ITGA2	interactor	2	1.000	0	FG-GAP (PF01839, IPR013517): FG-GAP repeat Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region Integrin_alpha2 (PF08441, IPR013649): Integrin alpha VWA (PF00092, IPR002035, SM00327): von Willebrand factor type A domain VCBS (PF13517): Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP_2 (PF14312, IPR013517): FG-GAP repeat
47	ITGB1	suppressor	7	0.381	138.645	EGF_2 (PF07974, IPR013111): EGF-like domain Integrin_b_cyt (PF08725, IPR014836): Integrin beta cytoplasmic domain Integrin_B_tail (PF07965, IPR012896): Integrin beta tail domain Integrin_beta (PF00362, IPR002369, SM00187): Integrin beta chain VWA domain PSI_integrin (PF17205): Integrin plexin domain
48	KIAA0232	interactor	1	0	0	DUF4603 (PF15376, IPR027871): Domain of unknown function (DUF4603)
49	LATS2	suppressor	7	0.533	32.623	Pkinase (PF00069, IPR000719): Protein kinase domain Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
50	LIN52	interactor	2	1.000	0	LIN52 (PF10044, IPR018737): Retinal tissue protein
51	LIPH	interactor	1	0	0	Lipase (PF00151, IPR013818): Lipase
52	LZTS2	suppressor	4	0.667	1.400	CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal DUF1127 (PF06568, IPR009506): Domain of unknown function (DUF1127) Fez1 (PF06818): Fez1 ADIP (PF11559, IPR021622): Afadin- and alpha -actinin-Binding DUF4250 (PF14056, IPR025346): Domain of unknown function (DUF4250)
53	MAG	interactor	2	0	15.649	C2-set_2 (PF08205, IPR013162): CD80-like C2-set immunoglobulin domain V-set (PF07686, IPR013106): Immunoglobulin V-set domain Ig_3 (PF13927): Immunoglobulin domain Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
54	MAP3K1	oncoprotein	8	0.524	17.901	zf-Di19 (PF05605, IPR008598): Drought induced 19 protein (Di19), zinc-binding Pkinase (PF00069, IPR000719): Protein kinase domain zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain Phostensin_N (PF13916, IPR025903): PP1-regulatory protein, Phostensin N-terminal
55	MAP3K5	oncoprotein	7	0.333	33.956	Pkinase (PF00069, IPR000719): Protein kinase domain DUF4071 (PF13281, IPR025136): Domain of unknown function (DUF4071)
56	MATN2	interactor	2	0	0	VWA (PF00092, IPR002035, SM00327): von Willebrand factor type A domain Matrilin_ccoil (PF10393, IPR019466): Trimeric coiled-coil oligomerisation domain of matrilin FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site
57	MED23	interactor	8	0.607	11.974	Med23 (PF11573, IPR021629): Mediator complex subunit 23
58	MFSD13A	interactor	3	0.333	16.491	MFS_2 (PF13347): MFS/sugar transport protein
59	MMP2	oncoprotein	3	1.000	0	Peptidase_M10 (PF00413, IPR001818): Matrixin PG_binding_1 (PF01471, IPR002477): Putative peptidoglycan binding domain Hemopexin (PF00045, IPR018487, SM00120): Hemopexin
60	MOV10	interactor	9	0.389	64.342	AAA_12 (PF13087): AAA domain AAA_30 (PF13604): AAA domain
61	NID1	protein found in more fusions	2	0	0	EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain G2F (PF07474, IPR006605, SM00682): G2F domain NIDO (PF06119, IPR003886, SM00539): Nidogen-like Ldl_recept_b (PF00058, IPR000033, SM00135): Low-density lipoprotein receptor repeat class B Thyroglobulin_1 (PF00086, IPR000716, SM00211): Thyroglobulin type-1 repeat cEGF (PF12662, IPR026823): Complement Clr-like EGF-like EGF_3 (PF12947, IPR024731): EGF domain FXa_inhibition (PF14670): Coagulation Factor Xa inhibitory site
62	NID2	interactor	1	0	0	EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain G2F (PF07474, IPR006605, SM00682): G2F domain NIDO (PF06119, IPR003886, SM00539): Nidogen-like SGL (PF08450, IPR013658): SMP-30/Gluconolaconase/LRE-like region Ldl_recept_b (PF00058, IPR000033, SM00135): Low-density lipoprotein receptor repeat class B Thyroglobulin_1 (PF00086, IPR000716, SM00211): Thyroglobulin type-1 repeat cEGF (PF12662, IPR026823): Complement Clr-like EGF-like EGF_3 (PF12947, IPR024731): EGF domain
63	NTRK1	oncoprotein	24	0.174	577.481	I-set (PF07679, IPR013098): Immunoglobulin I-set domain Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase LRR_8 (PF13855, IPR001611): Leucine rich repeat TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
64	NXF1	interactor	11	0.200	155.816	NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain Tap-RNA_bind (PF09162, IPR015245): Tap, RNA-binding TAP_C (PF03943, IPR005637, SM00804): TAP C-terminal domain LRR_8 (PF13855, IPR001611): Leucine rich repeat
65	OTUB1	interactor	6	0.267	95.222	Peptidase_C65 (PF10275, IPR019400): Peptidase C65 Otubain
66	PARK2	suppressor	8	0.429	33.897	IBR (PF01485, IPR002867, SM00647): IBR domain, a half RING-finger domain ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
67	PDGFA	oncoprotein	2	1.000	0	PDGF (PF00341, IPR000072, SM00141): PDGF/VEGF domain PDGF_N (PF04692, IPR006782): Platelet-derived growth factor, N terminal region SyrA (PF11089, IPR024239): Exopolysaccharide production repressor
68	PDGFB	oncoprotein	5	0.500	3.000	PDGF (PF00341, IPR000072, SM00141): PDGF/VEGF domain PDGF_N (PF04692, IPR006782): Platelet-derived growth factor, N terminal region
69	PKD1	suppressor	2	0	0	Stress-antifung (PF01657, IPR002902): Salt stress response/antifungal LRRCT (PF01463, IPR000483, SM00082): Leucine rich repeat C-terminal domain LRRNT (PF01462, IPR000372, SM00013): Leucine rich repeat N-terminal domain PKD (PF00801, IPR000601, SM00089): PKD domain PKD_channel (PF08016, IPR013122): Polycystin cation channel PLAT (PF01477, IPR001024, SM00308): PLAT/LH2 domain REJ (PF02010, IPR002859): REJ domain WSC (PF01822, IPR002889, SM00321): WSC domain Lectin_C (PF00059, IPR001304, SM00034): Lectin C-type domain LRR_8 (PF13855, IPR001611): Leucine rich repeat fn3_3 (PF14686, IPR029413): Polysaccharide lyase family 4, domain II
70	PPP1R3F	interactor	1	0	0	CBM_21 (PF03370, IPR005036): Carbohydrate/starch-binding module (family 21) K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
71	PRD	interactor	1	0	0	NA
72	PRELP	interactor	1	0	0	LRRNT (PF01462, IPR000372, SM00013): Leucine rich repeat N-terminal domain LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_8 (PF13855, IPR001611): Leucine rich repeat
73	PRKACA	interactor	9	0.444	18.854	Pkinase (PF00069, IPR000719): Protein kinase domain
74	PRKACB	interactor	8	0.500	22.542	Pkinase (PF00069, IPR000719): Protein kinase domain
75	PRKAR1A	suppressor	8	0.571	21.850	RIIa (PF02197, IPR003117, SM00394): Regulatory subunit of type II PKA R-subunit cNMP_binding (PF00027, IPR000595, SM00100): Cyclic nucleotide-binding domain
76	RAD54L2	interactor	2	1.000	0	SNF2_N (PF00176, IPR000330): SNF2 family N-terminal domain Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain FAM176 (PF14851): FAM176 family ERCC3_RAD25_C (PF16203, IPR032438): ERCC3/RAD25/XPB C-terminal helicase
77	RB1	suppressor	10	0.422	49.422	RB_A (PF01858, IPR002720): Retinoblastoma-associated protein A domain RB_B (PF01857, IPR002719): Retinoblastoma-associated protein B domain Rb_C (PF08934, IPR015030): Rb C-terminal domain DUF3452 (PF11934, IPR024599): Domain of unknown function (DUF3452) DUF4592 (PF15262, IPR028030): Domain of unknown function (DUF4592)
78	RBL1	suppressor	8	0.464	24.824	RB_A (PF01858, IPR002720): Retinoblastoma-associated protein A domain RB_B (PF01857, IPR002719): Retinoblastoma-associated protein B domain Rb_C (PF08934, IPR015030): Rb C-terminal domain DUF3452 (PF11934, IPR024599): Domain of unknown function (DUF3452)
79	RBL2	suppressor	7	0.429	52.651	CAP_N (PF01213, IPR013992): Adenylate cyclase associated (CAP) N terminal Pap_E4 (PF02711, IPR003861): E4 protein RB_A (PF01858, IPR002720): Retinoblastoma-associated protein A domain RB_B (PF01857, IPR002719): Retinoblastoma-associated protein B domain SLH (PF00395, IPR001119): S-layer homology domain TFIIB (PF00382, IPR013150): Transcription factor TFIIB repeat DUF3452 (PF11934, IPR024599): Domain of unknown function (DUF3452)
80	RFPL2	interactor	2	1.000	0	SPRY (PF00622, IPR003877, SM00449): SPRY domain PRY (PF13765, IPR006574, SM00589): SPRY-associated domain RDM (PF11002, IPR022723): RFPL defining motif (RDM) zf-C3HC4_4 (PF15227): zinc finger of C3HC4-type, RING
81	RNF169	interactor	4	0.333	8.323	IncA (PF04156, IPR007285): IncA protein zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
82	RNH1	suppressor	2	0	11.805	LRR_1 (PF00560, IPR001611): Leucine Rich Repeat Metallothio_Euk (PF12749, IPR024306): Eukaryotic metallothionein LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies) LRR_6 (PF13516, IPR001611): Leucine Rich repeat
83	SFN	suppressor	11	0.311	39.177	14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein
84	SH3GL2	oncoprotein	6	0.500	54.686	BAR (PF03114, IPR004148, SM00721): BAR domain SH3_2 (PF07653, IPR011511): Variant SH3 domain
85	SIPA1L1	interactor	4	0.667	1.500	PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF) Rap_GAP (PF02145, IPR000331): Rap/ran-GAP SPAR_C (PF11881, IPR021818): C-terminal domain of SPAR protein DUF4164 (PF13747, IPR025310): Domain of unknown function (DUF4164) IQCJ-SCHIP1 (PF15157, IPR029362): Fusion protein IQCJ-SCHIP1 with IQ-like motif
86	SMAD3	oncoprotein	10	0.389	53.938	MH1 (PF03165, IPR003619, SM00523): MH1 domain MH2 (PF03166, IPR001132, SM00524): MH2 domain
87	SNCA	interactor	9	0.250	77.705	Synuclein (PF01387, IPR001058): Synuclein
88	SPARC	suppressor	2	1.000	0	FOLN (PF09289, IPR015369, SM00274): Follistatin/Osteonectin-like EGF domain Kazal_1 (PF00050, IPR002350): Kazal-type serine protease inhibitor domain SPARC_Ca_bdg (PF10591, IPR019577): Secreted protein acidic and rich in cysteine Ca binding region
89	SRSF1	protein found in more fusions	15	0.374	67.314	Corona_nucleoca (PF00937, IPR001218): Coronavirus nucleocapsid protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication (PF13865, IPR025715): C-terminal duplication domain of Friend of PRMT1
90	SRSF4	interactor	5	0.600	4.800	Corona_nucleoca (PF00937, IPR001218): Coronavirus nucleocapsid protein RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
91	SRSF5	interactor	7	0.810	2.001	DUF1777 (PF08648, IPR013957): Protein of unknown function (DUF1777) RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PRP38_assoc (PF12871, IPR024767): Pre-mRNA-splicing factor 38-associated hydrophilic C-term
92	TBP	interactor	7	0.800	3.128	TBP (PF00352, IPR000814): Transcription factor TFIID (or TATA-binding protein, TBP) EPL1 (PF10513, IPR019542): Enhancer of polycomb-like Med3 (PF11593, IPR020998): Mediator complex subunit 3 fungal
93	THBS1	suppressor	6	0.467	59.248	EGF (PF00008, IPR000742, SM00181): EGF-like domain EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain TSP_3 (PF02412, IPR003367): Thrombospondin type 3 repeat TSP_C (PF05735, IPR008859): Thrombospondin C-terminal region VWC (PF00093, IPR001007, SM00214): von Willebrand factor type C domain EndIII_4Fe-2S (PF10576, IPR003651): Iron-sulfur binding domain of endonuclease III TSP_1 (PF00090, IPR000884, SM00209): Thrombospondin type 1 domain cEGF (PF12662, IPR026823): Complement Clr-like EGF-like EGF_3 (PF12947, IPR024731): EGF domain Laminin_G_3 (PF13385): Concanavalin A-like lectin/glucanases superfamily
94	TMTC4	interactor	3	0.333	15.992	DUF1736 (PF08409, IPR013618): Domain of unknown function (DUF1736) TPR_1 (PF00515, IPR001440): Tetratricopeptide repeat DUF3382 (PF11862, IPR021807): Domain of unknown function (DUF3382) TPR_12 (PF13424): Tetratricopeptide repeat TPR_14 (PF13428): Tetratricopeptide repeat TPR_17 (PF13431): Tetratricopeptide repeat TPR_16 (PF13432): Tetratricopeptide repeat DUF4131 (PF13567, IPR025405): Domain of unknown function (DUF4131)
95	TRAF3	oncoprotein	7	0.267	34.013	ATG16 (PF08614, IPR013923): Autophagy protein 16 (ATG16) S-AdoMet_synt_M (PF02772, IPR022629): S-adenosylmethionine synthetase, central domain zf-C3HC4 (PF00097, IPR018957): Zinc finger, C3HC4 type (RING finger) zf-TRAF (PF02176, IPR001293): TRAF-type zinc finger zf-RING_2 (PF13639, IPR001841, SM00184): Ring finger domain MPS2 (PF17060, IPR031433): Monopolar spindle protein 2 Spc29 (PF17082, IPR031392): Spindle Pole Component 29
96	TROAP	protein found in more fusions	6	0.400	11.173	Strep_pep (PF14404, IPR025744): Ribosomally synthesized peptide in Streptomyces species
97	TXN	oncoprotein	5	0.200	70.583	Thioredoxin (PF00085, IPR013766): Thioredoxin
98	UBC	protein found in more fusions	16	0.143	343.118	ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
99	UBXN11	interactor	1	0	0	DivIC (PF04977, IPR007060): Septum formation initiator SEP (PF08059, IPR012989, SM00553): SEP domain UBX (PF00789, IPR001012, SM00166): UBX domain DUF4200 (PF13863, IPR025252): Domain of unknown function (DUF4200) TRPM_tetra (PF16519, IPR032415): Tetramerisation domain of TRPM
100	VWF	interactor	1	0	0	Antistasin (PF02822, IPR004094): Antistasin family C8 (PF08742, IPR014853, SM00832): C8 domain Metallothio_5 (PF02067, IPR000966): Metallothionein family 5 Pacifastin_I (PF05375, IPR008037): Pacifastin inhibitor (LCMII) TIL (PF01826, IPR002919): Trypsin Inhibitor like cysteine rich domain VWA (PF00092, IPR002035, SM00327): von Willebrand factor type A domain VWC (PF00093, IPR001007, SM00214): von Willebrand factor type C domain VWD (PF00094, IPR001846, SM00216): von Willebrand factor type D domain VWA_N2 (PF16164, IPR032361): VWA N-terminal
101	XPO1	interactor	17	0.301	150.423	CRM1_C (PF08767, IPR014877, SM01102): CRM1 C terminal Hydrolase_3 (PF08282, IPR023214): haloacid dehalogenase-like hydrolase IBN_N (PF03810, IPR001494, SM00913): Importin-beta N-terminal domain Xpo1 (PF08389, IPR013598): Exportin 1-like protein Vac14_Fab1_bd (PF12755, IPR032878): Vacuolar 14 Fab1-binding region
102	YWHAG	protein found in more fusions	14	0.372	78.261	14-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein

B a c k t o T o p ⇑

Fusion ID: Protein names:	1277 1859
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