Find Fusion Network

Fusion ID:
Protein names:

Level of PPIs:
or Upload text file:
Update repository
Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

Powered by Cytoscape Web for: parental proteins CNN3, GGT7 (from a repository: Wed Jul 24 04:24:18 2019)

Cytoscape Web will replace the contents your graph
PPI Properties:

Click on nodes
or edges

Layout Tree
Force Directed
Export graph
PDF file
SVG file
SIF file
XML file
GraphML file

Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)16
The number (and %) of the onco-proteins2 (12.50 %)
The number (and %) of the tumor suppressors0 (0.00 %)
Total number of binary PPIs (saturation %)25 (20.83 %)
The number (and %) of affected PPIs15 (60.00 %)
The number of possible different fusions2
PPI diameter5
PPI radius3
The average degree of PPI2.625
Assortativity coefficient-0.0645
The network average Clustering coefficient0.442
The number (and %) of a zero Clustering coefficients6 (37.50 %)
The number (and %) of a zero Betweenness Centrality9 (56.25 %)


List of the fusions

PPI for parental proteins: GGT7,CNN3 All fusions
Proteins found in more fusions GGT7 (see 2 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Domains (Pfam, InterPro, SMART): description
1 GGT7parental protein70.067118.000G_glu_transpept (PF01019, IPR000101): Gamma-glutamyltranspeptidase
2 CNN3parental protein80.179139.000Calponin (PF00402, IPR000557): Calponin family repeat
CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
3 CARM1oncoprotein21.0000K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
PRMT5 (PF05185, IPR025799): PRMT5 arginine-N-methyltransferase
CBP_GIL (PF10995, IPR017745): GGDEF I-site like or GIL domain
CARM1 (PF11531, IPR020989): Coactivator-associated arginine methyltransferase 1 N terminal
4 CNN2interactor21.0000Calponin (PF00402, IPR000557): Calponin family repeat
CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
5 DCP2interactor21.0000DCP2 (PF05026, IPR007722, SM01125): Dcp2, box A domain
NUDIX (PF00293, IPR000086): NUDIX domain
6 EMDinteractor40.6671.000LEM (PF03020, IPR003887, SM00540): LEM domain
SR-25 (PF10500, IPR019532): Nuclear RNA-splicing-associated protein
7 FAM96Binteractor21.0000DUF59 (PF01883, IPR002744): Domain of unknown function DUF59
8 GPR25interactor1007tm_1 (PF00001, IPR000276): 7 transmembrane receptor (rhodopsin family)
9 LHFPL5interactor100L_HMGIC_fpl (PF10242, IPR019372): Lipoma HMGIC fusion partner-like protein
10 MALLinteractor100MARVEL (PF01284, IPR008253): Membrane-associating domain
PsbM (PF05151, IPR007826): Photosystem II reaction centre M protein (PsbM)
11 MTHFD1Linteractor21.0000FTHFS (PF01268, IPR000559): Formate--tetrahydrofolate ligase
THF_DHG_CYH (PF00763, IPR020630): Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain
THF_DHG_CYH_C (PF02882, IPR020631): Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain
12 NTRK1oncoprotein50.5003.000I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
13 PAN2interactor30.6671.000RNase_T (PF00929, IPR013520): Exonuclease
UCH_1 (PF13423, IPR001394): Ubiquitin carboxyl-terminal hydrolase
WD40_like (PF17005, IPR031544): WD40-like domain
14 TMEM242interactor20108.000DUF1358 (PF07096, IPR009792): Protein of unknown function (DUF1358)
TAT_signal (PF10518, IPR019546): TAT (twin-arginine translocation) pathway signal sequence
15 VKORC1interactor30112.000VKOR (PF07884, IPR012932, SM00756): Vitamin K epoxide reductase family
16 YKT6interactor100Synaptobrevin (PF00957, IPR001388): Synaptobrevin
Longin (PF13774, IPR010908): Regulated-SNARE-like domain

B a c k    t o    T o p ⇑