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Visible interactions: all affected independent (normal) nothing (blank)

Visualization interactions

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Statistics and Network structure information

Statistic of PPI Value(s)
The number of interactors (fusion and proteins)140
The number (and %) of the onco-proteins34 (24.29 %)
The number (and %) of the tumor suppressors13 (9.29 %)
Total number of binary PPIs (saturation %)725 (7.45 %)
The number (and %) of affected PPIs139 (19.17 %)
The number of possible different fusions15
PPI diameter4
PPI radius2
The average degree of PPI9.943
Assortativity coefficient-0.2425
The network average Clustering coefficient0.462
The number (and %) of a zero Clustering coefficients12 (8.57 %)
The number (and %) of a zero Betweenness Centrality27 (19.29 %)

ACTIVE INTERACTORS


List of the fusions

PPI for parental proteins: CLNS1A,CDH2 All fusions
Proteins found in more fusions EXOC5 (see 1 fusions); G3BP1 (see 1 fusions); PRMT5 (see 2 fusions); CTNNA1 (see 3 fusions); WDR77 (see 1 fusions); RAC1 (see 1 fusions); CREBBP (see 6 fusions); UBQLN1 (see 2 fusions); RBFOX2 (see 2 fusions); LGALS3 (see 2 fusions); MDH2 (see 1 fusions); CSNK2A1 (see 1 fusions); UBC (see 1 fusions); TPD52L2 (see 2 fusions);

List of active interactors

# Name Type Number of PPI (degree) Clustering
Coefficient
Betweenness
Centrality
Domains (Pfam, InterPro, SMART): description
1 CLNS1Aparental protein860.0777272.568Voldacs (PF03517): Regulator of volume decrease after cellular swelling
2 CDH2parental protein530.0963684.705Cadherin_C (PF01049, IPR000233): Cadherin cytoplasmic region
Cadherin_pro (PF08758, IPR014868, SM01055): Cadherin prodomain like
Cadherin (PF00028, IPR002126, SM00112): Cadherin domain
EphA2_TM (PF14575, IPR027936): Ephrin type-A receptor 2 transmembrane domain
Cadherin_3 (PF16184): Cadherin-like
3 ACTA1interactor60.06796.957Actin (PF00022, IPR004000, SM00268): Actin
4 ADCYAP1interactor100Hormone_2 (PF00123, IPR000532, SM00070): Peptide hormone
5 AGO3interactor50.4007.058ArgoL1 (PF08699, IPR014811, SM01163): Argonaute linker 1 domain
PAZ (PF02170, IPR003100, SM00949): PAZ domain
Piwi (PF02171, IPR003165, SM00950): Piwi domain
ArgoN (PF16486, IPR032474): N-terminal domain of argonaute
ArgoMid (PF16487, IPR032473): Mid domain of argonaute
ArgoL2 (PF16488, IPR032472): Argonaute linker 2 domain
6 ALKBH3interactor30.6670.1822OG-FeII_Oxy_2 (PF13532, IPR027450): 2OG-Fe(II) oxygenase superfamily
7 ARRB2interactor200.189199.871Arrestin_C (PF02752, IPR011022, SM01017): Arrestin (or S-antigen), C-terminal domain
Arrestin_N (PF00339, IPR011021): Arrestin (or S-antigen), N-terminal domain
8 ATIConcoprotein50.50018.889AICARFT_IMPCHas (PF01808, IPR002695, SM00798): AICARFT/IMPCHase bienzyme
MGS (PF02142, IPR011607, SM00851): MGS-like domain
9 BOConcoprotein31.0000fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
V-set (PF07686, IPR013106): Immunoglobulin V-set domain
Ig_3 (PF13927): Immunoglobulin domain
ISET-FN3_linker (PF16625): Unstructured linking region I-set and fnIII on Brother of CDO
Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
10 CCNA2oncoprotein60.60022.074Cyclin_C (PF02984, IPR004367): Cyclin, C-terminal domain
Cyclin_N (PF00134, IPR006671): Cyclin, N-terminal domain
Cyclin_N2 (PF16500, IPR032447): N-terminal region of cyclin_N
11 CDH11suppressor21.0000Cadherin_C (PF01049, IPR000233): Cadherin cytoplasmic region
Rifin_STEVOR (PF02009, IPR002858): Rifin/stevor family
Cadherin (PF00028, IPR002126, SM00112): Cadherin domain
Cadherin_3 (PF16184): Cadherin-like
12 CDH4suppressor100Cadherin_C (PF01049, IPR000233): Cadherin cytoplasmic region
Cadherin_pro (PF08758, IPR014868, SM01055): Cadherin prodomain like
Cadherin (PF00028, IPR002126, SM00112): Cadherin domain
Cadherin_3 (PF16184): Cadherin-like
13 CDONoncoprotein31.0000fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
Glyco_hydro_76 (PF03663, IPR005198): Glycosyl hydrolase family 76
I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Fer4_2 (PF12797, IPR001450): 4Fe-4S binding domain
Ig_3 (PF13927): Immunoglobulin domain
Izumo-Ig (PF16706, IPR032699): Izumo-like Immunoglobulin domain
14 CREBBPsuppressor70.26789.506Creb_binding (PF09030, IPR014744): Creb binding
DUF902 (PF06001, IPR010303): Domain of Unknown Function (DUF902)
Forkhead_N (PF08430, IPR013638): Forkhead N-terminal region
KIX (PF02172, IPR003101): KIX domain
MAS20 (PF02064, IPR002056): MAS20 protein import receptor
TPX2 (PF06886, IPR027329): Targeting protein for Xklp2 (TPX2)
zf-TAZ (PF02135, IPR000197, SM00551): TAZ zinc finger
ANAPC_CDC26 (PF10471, IPR018860): Anaphase-promoting complex APC subunit CDC26
HAT_KAT11 (PF08214, IPR013178): Histone acetylation protein
Bromodomain (PF00439, IPR001487, SM00297): Bromodomain
ZZ (PF00569, IPR000433, SM00291): Zinc finger, ZZ type
DUF3729 (PF12526, IPR022202): Protein of unknown function (DUF3729)
DUF4834 (PF16118, IPR032272): Domain of unknown function (DUF4834)
15 CSNK2A1oncoprotein100.36178.786Pkinase (PF00069, IPR000719): Protein kinase domain
16 CTNNA1oncoprotein100.50049.590Vinculin (PF01044, IPR006077): Vinculin family
17 CTNNB1oncoprotein170.184498.491Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
DUF3361 (PF11841, IPR024574): Domain of unknown function (DUF3361)
HEAT_EZ (PF13513): HEAT-like repeat
18 CTNND1suppressor60.46723.436Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
Ebp2 (PF05890, IPR008610): Eukaryotic rRNA processing protein EBP2
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
19 CTPS1interactor90.39324.995CTP_synth_N (PF06418, IPR017456): CTP synthase N-terminus
GATase (PF00117, IPR017926): Glutamine amidotransferase class-I
20 DBN1oncoprotein120.273124.829Pinin_SDK_memA (PF04696, IPR006786): pinin/SDK/memA/ protein conserved region
Cofilin_ADF (PF00241, IPR002108, SM00102): Cofilin/tropomyosin-type actin-binding protein
CAF-1_p150 (PF11600): Chromatin assembly factor 1 complex p150 subunit, N-terminal
MSA-2c (PF12238, IPR021060): Merozoite surface antigen 2c
21 DDAH2interactor40.6670.967Amidinotransf (PF02274, IPR003198): Amidinotransferase
22 DDR1oncoprotein100Lamprin (PF06403, IPR009437): Lamprin
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
F5_F8_type_C (PF00754, IPR000421, SM00231): F5/8 type C domain
DUF4381 (PF14316, IPR025489): Domain of unknown function (DUF4381)
23 DDR2suppressor21.0000Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
F5_F8_type_C (PF00754, IPR000421, SM00231): F5/8 type C domain
TMEM154 (PF15102, IPR028064): TMEM154 protein family
24 EIF4A3interactor190.458114.649DEAD (PF00270, IPR011545): DEAD/DEAH box helicase
Helicase_C (PF00271, IPR001650, SM00490): Helicase conserved C-terminal domain
25 EPB41suppressor30.6670.4324_1_CTD (PF05902, IPR008379): 4.1 protein C-terminal domain (CTD)
FA (PF08736, IPR014847): FERM adjacent (FA)
FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain
FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
SAB (PF04382, IPR007477): SAB domain
26 EPB41L3suppressor130.47433.2714_1_CTD (PF05902, IPR008379): 4.1 protein C-terminal domain (CTD)
FA (PF08736, IPR014847): FERM adjacent (FA)
FERM_C (PF09380, IPR018980): FERM C-terminal PH-like domain
FERM_M (PF00373, IPR019748): FERM central domain
FERM_N (PF09379, IPR018979): FERM N-terminal domain
RNA_pol_Rpc4 (PF05132, IPR007811): RNA polymerase III RPC4
SAB (PF04382, IPR007477): SAB domain
27 EXOC5protein found in more fusions31.0000Sec10 (PF07393, IPR009976): Exocyst complex component Sec10
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
28 FBLN7interactor21.0000EGF (PF00008, IPR000742, SM00181): EGF-like domain
EGF_CA (PF07645, IPR001881, SM00179): Calcium-binding EGF domain
Sushi (PF00084, IPR000436, SM00032): Sushi repeat (SCR repeat)
cEGF (PF12662, IPR026823): Complement Clr-like EGF-like
EGF_3 (PF12947, IPR024731): EGF domain
29 FBXO45interactor40.66714.488SPRY (PF00622, IPR003877, SM00449): SPRY domain
F-box-like (PF12937, IPR001810): F-box-like
30 FBXO6interactor240.167500.211FBA (PF04300, IPR007397): F-box associated region
F-box-like (PF12937, IPR001810): F-box-like
31 FN1oncoprotein400.146926.919fn1 (PF00039, IPR000083, SM00058): Fibronectin type I domain
fn2 (PF00040, IPR000562, SM00059): Fibronectin type II domain
fn3 (PF00041, IPR003961, SM00060): Fibronectin type III domain
DUF2369 (PF10179, IPR019326): Uncharacterised conserved protein (DUF2369)
32 G3BP1protein found in more fusions80.42930.666NTF2 (PF02136, IPR002075): Nuclear transport factor 2 (NTF2) domain
RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
DUF3306 (PF11748, IPR021735): Protein of unknown function (DUF3306)
PTPRCAP (PF15713, IPR016553): Protein tyrosine phosphatase receptor type C-associated
33 GAAinteractor40.6675.175Glyco_hydro_31 (PF01055, IPR000322): Glycosyl hydrolases family 31
Trefoil (PF00088, IPR000519, SM00018): Trefoil (P-type) domain
Gal_mutarotas_2 (PF13802, IPR025887): Galactose mutarotase-like
NtCtMGAM_N (PF16863, IPR031727): N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase
DUF5110 (PF17137): Domain of unknown function (DUF5110)
34 GAR1interactor50.6001.707Gar1 (PF04410, IPR007504): Gar1/Naf1 RNA binding region
35 GNA12oncoprotein100G-alpha (PF00503, IPR001019, SM00275): G-protein alpha subunit
36 GNA13interactor21.0000G-alpha (PF00503, IPR001019, SM00275): G-protein alpha subunit
37 HSPA5oncoprotein260.227405.565HSP70 (PF00012, IPR013126): Hsp70 protein
38 IARS2interactor50.7003.343Anticodon_1 (PF08264, IPR013155): Anticodon-binding domain of tRNA
tRNA-synt_1 (PF00133, IPR002300): tRNA synthetases class I (I, L, M and V)
zf-FPG_IleRS (PF06827, IPR010663): Zinc finger found in FPG and IleRS
39 ITGA2Binteractor21.0000FG-GAP (PF01839, IPR013517): FG-GAP repeat
Integrin_alpha (PF00357, IPR018184): Integrin alpha cytoplasmic region
Integrin_alpha2 (PF08441, IPR013649): Integrin alpha
VCBS (PF13517): Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella
40 JUPsuppressor120.242126.943Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
Atx10homo_assoc (PF09759, IPR019156): Spinocerebellar ataxia type 10 protein domain
HEAT_EZ (PF13513): HEAT-like repeat
HEAT_2 (PF13646): HEAT repeats
41 KTN1oncoprotein50.10055.330ETRAMP (PF09716, IPR006389): Malarial early transcribed membrane protein (ETRAMP)
Fez1 (PF06818): Fez1
Fib_alpha (PF08702, IPR012290): Fibrinogen alpha/beta chain family
Fzo_mitofusin (PF04799, IPR006884): fzo-like conserved region
HALZ (PF02183, IPR003106, SM00340): Homeobox associated leucine zipper
IncA (PF04156, IPR007285): IncA protein
OmpH (PF03938, IPR005632, SM00935): Outer membrane protein (OmpH-like)
PTPS (PF01242, IPR007115): 6-pyruvoyl tetrahydropterin synthase
Spectrin (PF00435, IPR002017): Spectrin repeat
TBPIP (PF07106, IPR010776): Tat binding protein 1(TBP-1)-interacting protein (TBPIP)
Jnk-SapK_ap_N (PF09744, IPR019143): JNK_SAPK-associated protein-1
TMF_TATA_bd (PF12325, IPR022091): TATA element modulatory factor 1 TATA binding
DUF4407 (PF14362, IPR025519): Domain of unknown function (DUF4407)
Fimbrial_PilY2 (PF14481, IPR029497): Type 4 fimbrial biogenesis protein PilY2
Muted (PF14942, IPR017243): Organelle biogenesis, Muted-like protein
BST2 (PF16716, IPR024886): Bone marrow stromal antigen 2
42 LGALS1interactor80.42921.015Gal-bind_lectin (PF00337, IPR001079, SM00908): Galactoside-binding lectin
43 LGALS3oncoprotein60.50019.998Gal-bind_lectin (PF00337, IPR001079, SM00908): Galactoside-binding lectin
44 LPPoncoprotein21.0000LIM (PF00412, IPR001781, SM00132): LIM domain
zf-C3HC4_3 (PF13920): Zinc finger, C3HC4 type (RING finger)
45 LRRC7interactor100LRR_1 (PF00560, IPR001611): Leucine Rich Repeat
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
LRR_4 (PF12799, IPR025875): Leucine Rich repeats (2 copies)
LRR_5 (PF13306, IPR026906): Leucine rich repeats (6 copies)
LRR_8 (PF13855, IPR001611): Leucine rich repeat
46 LSM10interactor21.0000LSM (PF01423, IPR001163): LSM domain
47 LSM11interactor31.0000LSM (PF01423, IPR001163): LSM domain
48 LSM2interactor80.8212.436LSM (PF01423, IPR001163): LSM domain
49 LSM3interactor90.58313.687LSM (PF01423, IPR001163): LSM domain
50 LSM6interactor60.8000.917LSM (PF01423, IPR001163): LSM domain
51 MAGOHinteractor150.43858.991Mago_nashi (PF02792, IPR004023): Mago nashi protein
52 MDH2protein found in more fusions50.50035.902Ldh_1_C (PF02866, IPR022383): lactate/malate dehydrogenase, alpha/beta C-terminal domain
Ldh_1_N (PF00056, IPR001236): lactate/malate dehydrogenase, NAD binding domain
53 MIFoncoprotein40.6672.638MIF (PF01187, IPR001398): Macrophage migration inhibitory factor (MIF)
54 MRPL23interactor80.5369.384Ribosomal_L23 (PF00276, IPR013025): Ribosomal protein L23
55 MRPL49interactor60.7331.176Img2 (PF05046, IPR007740): Mitochondrial large subunit ribosomal protein (Img2)
56 MRPL58interactor80.5719.222RF-1 (PF00472, IPR000352): RF-1 domain
57 MTHFD1interactor180.255293.183FTHFS (PF01268, IPR000559): Formate--tetrahydrofolate ligase
THF_DHG_CYH (PF00763, IPR020630): Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain
THF_DHG_CYH_C (PF02882, IPR020631): Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain
58 NACA2interactor40.16722.298NAC (PF01849, IPR002715): NAC domain
59 NDRG1suppressor70.28664.831Ndr (PF03096, IPR004142): Ndr family
60 NEDD8interactor160.238170.071ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
61 NENFinteractor180.268174.240Cyt-b5 (PF00173, IPR001199, SM01117): Cytochrome b5-like Heme/Steroid binding domain
62 NFE4interactor21.0000NA
63 NOS2interactor110.200163.392FAD_binding_1 (PF00667, IPR003097): FAD binding domain
Flavodoxin_1 (PF00258, IPR008254): Flavodoxin
NAD_binding_1 (PF00175, IPR001433): Oxidoreductase NAD-binding domain
NO_synthase (PF02898, IPR004030): Nitric oxide synthase, oxygenase domain
64 NTRK1oncoprotein520.0893132.980I-set (PF07679, IPR013098): Immunoglobulin I-set domain
Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
LRR_8 (PF13855, IPR001611): Leucine rich repeat
TPKR_C2 (PF16920, IPR031635): Tyrosine-protein kinase receptor C2 Ig-like domain
65 OSTF1interactor2010.517SH3_1 (PF00018, IPR001452, SM00326): SH3 domain
Ank_2 (PF12796, IPR020683): Ankyrin repeats (3 copies)
66 P4HBinteractor170.242236.092Glycos_trans_3N (PF02885, IPR017459): Glycosyl transferase family, helical bundle domain
Thioredoxin (PF00085, IPR013766): Thioredoxin
Thioredoxin_6 (PF13848): Thioredoxin-like domain
67 PAN2interactor230.249345.519RNase_T (PF00929, IPR013520): Exonuclease
UCH_1 (PF13423, IPR001394): Ubiquitin carboxyl-terminal hydrolase
WD40_like (PF17005, IPR031544): WD40-like domain
68 PCinteractor60.53329.535Biotin_carb_C (PF02785, IPR005482, SM00878): Biotin carboxylase C-terminal domain
Biotin_lipoyl (PF00364, IPR000089): Biotin-requiring enzyme
Biotin_carb_N (PF00289, IPR005481): Biotin carboxylase, N-terminal domain
CPSase_L_D2 (PF02786, IPR005479): Carbamoyl-phosphate synthase L chain, ATP binding domain
HMGL-like (PF00682, IPR000891): HMGL-like
PYC_OADA (PF02436, IPR003379): Conserved carboxylase domain
69 PDCD10interactor40.6671.417DUF1241 (PF06840, IPR009652): Protein of unknown function (DUF1241)
CENP-L (PF13092, IPR025204): Kinetochore complex Sim4 subunit Fta1
70 PDIA4interactor50.40038.042Calsequestrin (PF01216, IPR001393): Calsequestrin
Thioredoxin (PF00085, IPR013766): Thioredoxin
Thioredoxin_6 (PF13848): Thioredoxin-like domain
FAM176 (PF14851): FAM176 family
71 PDIA6interactor100.51133.362FAD_binding_7 (PF03441, IPR005101): FAD binding domain of DNA photolyase
Thioredoxin (PF00085, IPR013766): Thioredoxin
Thioredoxin_6 (PF13848): Thioredoxin-like domain
72 PDLIM1interactor200LIM (PF00412, IPR001781, SM00132): LIM domain
PDZ (PF00595, IPR001478, SM00228): PDZ domain (Also known as DHR or GLGF)
DUF4749 (PF15936, IPR031847): Domain of unknown function (DUF4749)
73 PFDN2interactor50.6006.558Prefoldin_2 (PF01920, IPR002777): Prefoldin subunit
74 PGAM1interactor21.0000His_Phos_1 (PF00300, IPR013078, SM00855): Histidine phosphatase superfamily (branch 1)
75 PIRinteractor30.6670.667Pirin (PF02678, IPR003829): Pirin
Pirin_C (PF05726, IPR008778): Pirin C-terminal cupin domain
76 PKP4interactor209.844Arm (PF00514, IPR000225, SM00185): Armadillo/beta-catenin-like repeat
HEAT (PF02985, IPR000357): HEAT repeat
77 PLIN3interactor110.24434.464Perilipin (PF03036, IPR004279): Perilipin family
78 PLS3interactor21.0000CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
EF-hand_5 (PF13202, IPR002048): EF hand
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
79 PPA1interactor60.40023.701Pyrophosphatase (PF00719, IPR008162): Inorganic pyrophosphatase
80 PPP2CAsuppressor80.32153.631Metallophos (PF00149, IPR004843): Calcineurin-like phosphoesterase
STPPase_N (PF16891, IPR031675): Serine-threonine protein phosphatase N-terminal domain
81 PPP4R2interactor21.0000BT1 (PF03092, IPR004324): BT1 family
PPP4R2 (PF09184, IPR015267): PPP4R2
82 PPT2interactor170.338104.875Abhydrolase_1 (PF00561, IPR000073): alpha/beta hydrolase fold
Palm_thioest (PF02089, IPR002472): Palmitoyl protein thioesterase
83 PRKCDBPsuppressor140.29779.895A1_Propeptide (PF07966, IPR012848): A1 Propeptide
PTRF_SDPR (PF15237, IPR026752): PTRF/SDPR family
84 PRMT5protein found in more fusions250.283279.692PRMT5 (PF05185, IPR025799): PRMT5 arginine-N-methyltransferase
85 PRPHinteractor30.6670.309Filament (PF00038, IPR001664): Intermediate filament protein
Filament_head (PF04732, IPR006821): Intermediate filament head (DNA binding) region
TolA_bind_tri (PF16331, IPR032519): TolA binding protein trimerisation
86 PSMA5oncoprotein100.46730.106Proteasome (PF00227, IPR001353): Proteasome subunit
Proteasome_A_N (PF10584, IPR000426, SM00948): Proteasome subunit A N-terminal signature
87 PTBP3interactor31.0000RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
RRM_5 (PF13893): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
88 PTMSinteractor2028.170Prothymosin (PF03247, IPR004931): Prothymosin/parathymosin family
U79_P34 (PF03064, IPR004138): HSV U79 / HCMV P34
89 PUM1interactor40.6671.969K_channel_TID (PF07941, IPR012897): Potassium channel Kv1.4 tandem inactivation domain
PUF (PF00806, IPR001313, SM00025): Pumilio-family RNA binding repeat
YppG (PF14179, IPR025555): YppG-like protein
90 RAB8Boncoprotein50.30018.807Ras (PF00071, IPR001806, SM00173): Ras family
91 RAC1oncoprotein90.28650.342Ras (PF00071, IPR001806, SM00173): Ras family
92 RAD23Aoncoprotein100.306151.477UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
XPC-binding (PF09280, IPR015360): XPC-binding domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
93 RBFOX2protein found in more fusions50.8330.500RRM_1 (PF00076, IPR000504, SM00361): RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)
Fox-1_C (PF12414, IPR025670): Calcitonin gene-related peptide regulator C terminal
94 RHOAsuppressor60.26736.555Ras (PF00071, IPR001806, SM00173): Ras family
95 RPL14interactor180.464160.474KOW (PF00467, IPR005824, SM00739): KOW motif
Ribosomal_L14e (PF01929, IPR002784): Ribosomal protein L14
UPF0688 (PF15772, IPR031530): UPF0688 family
96 RPL21interactor180.477112.153Ribosomal_L21e (PF01157, IPR001147): Ribosomal protein L21e
97 RPL3interactor200.416210.485Ribosomal_L3 (PF00297, IPR000597): Ribosomal protein L3
98 RPL32interactor150.50596.460Ribosomal_L32e (PF01655, IPR001515): Ribosomal protein L32
99 RPL8interactor200.437182.496Ribosomal_L2 (PF00181, IPR022666): Ribosomal Proteins L2, RNA binding domain
Ribosomal_L2_C (PF03947, IPR022669): Ribosomal Proteins L2, C-terminal domain
100 RPS16interactor180.464150.008Ribosomal_S9 (PF00380, IPR000754): Ribosomal protein S9/S16
101 RPS2interactor190.462257.551Ribosomal_S5 (PF00333, IPR013810): Ribosomal protein S5, N-terminal domain
Ribosomal_S5_C (PF03719, IPR005324): Ribosomal protein S5, C-terminal domain
102 RPS21interactor110.473115.395Ribosomal_S21e (PF01249, IPR001931): Ribosomal protein S21e
103 RPS26interactor160.58382.751Ribosomal_S26e (PF01283, IPR000892): Ribosomal protein S26e
104 RPS6KB2interactor100.26749.500Pkinase (PF00069, IPR000719): Protein kinase domain
Pkinase_C (PF00433, IPR017892): Protein kinase C terminal domain
105 RYKoncoprotein40.6671.409Pkinase_Tyr (PF07714, IPR001245): Protein tyrosine kinase
WIF (PF02019, IPR003306, SM00469): WIF domain
106 S100A6interactor31.0000S_100 (PF01023, IPR013787): S-100/ICaBP type calcium binding domain
EF-hand_7 (PF13499, IPR011992): EF-hand domain pair
107 SARS2interactor70.61917.545tRNA-synt_2b (PF00587, IPR002314): tRNA synthetase class II core domain (G, H, P, S and T)
DUF2312 (PF10073, IPR018753): Uncharacterized protein conserved in bacteria (DUF2312)
DUF4445 (PF14574, IPR027980): Domain of unknown function (DUF4445)
108 SEC24Ainteractor50.50030.549Gelsolin (PF00626, IPR007123): Gelsolin repeat
Sec23_BS (PF08033, IPR012990): Sec23/Sec24 beta-sandwich domain
Sec23_helical (PF04815, IPR006900): Sec23/Sec24 helical domain
Sec23_trunk (PF04811, IPR006896): Sec23/Sec24 trunk domain
zf-Sec23_Sec24 (PF04810, IPR006895): Sec23/Sec24 zinc finger
109 SEC24Cinteractor70.52428.412Gelsolin (PF00626, IPR007123): Gelsolin repeat
Sec23_BS (PF08033, IPR012990): Sec23/Sec24 beta-sandwich domain
Sec23_helical (PF04815, IPR006900): Sec23/Sec24 helical domain
Sec23_trunk (PF04811, IPR006896): Sec23/Sec24 trunk domain
zf-Sec23_Sec24 (PF04810, IPR006895): Sec23/Sec24 zinc finger
110 SKP1oncoprotein80.32169.097Skp1 (PF01466, IPR016072, SM00512): Skp1 family, dimerisation domain
Skp1_POZ (PF03931, IPR016073): Skp1 family, tetramerisation domain
111 SMURF1interactor180.294165.989C2 (PF00168, IPR000008, SM00239): C2 domain
WW (PF00397, IPR001202, SM00456): WW domain
HECT (PF00632, IPR000569, SM00119): HECT-domain (ubiquitin-transferase)
112 SNRPBinteractor170.50045.484LSM (PF01423, IPR001163): LSM domain
113 SNRPD1interactor200.437202.128API5 (PF05918, IPR008383): Apoptosis inhibitory protein 5 (API5)
LSM (PF01423, IPR001163): LSM domain
114 SNRPD2interactor170.49354.507LSM (PF01423, IPR001163): LSM domain
115 SNRPD3interactor200.447172.243LSM (PF01423, IPR001163): LSM domain
116 SNRPEinteractor130.59025.535LSM (PF01423, IPR001163): LSM domain
117 SNRPFinteractor90.66711.300LSM (PF01423, IPR001163): LSM domain
118 SNRPGinteractor60.8670.583LSM (PF01423, IPR001163): LSM domain
119 SNX12interactor100PX (PF00787, IPR001683, SM00312): PX domain
120 SPTBN1suppressor180.216264.490CH (PF00307, IPR001715, SM00033): Calponin homology (CH) domain
COG2 (PF06148, IPR024602): COG (conserved oligomeric Golgi) complex component, COG2
DUF1764 (PF08576, IPR013885): Eukaryotic protein of unknown function (DUF1764)
Spectrin (PF00435, IPR002017): Spectrin repeat
PH_9 (PF15410): Pleckstrin homology domain
121 SSR4interactor80.286126.449TRAP-delta (PF05404, IPR008855): Translocon-associated protein, delta subunit precursor (TRAP-delta)
OppC_N (PF12911, IPR025966): N-terminal TM domain of oligopeptide transport permease C
122 SUPT5Hinteractor80.35794.673KOW (PF00467, IPR005824, SM00739): KOW motif
Ribonuc_P_40 (PF08584, IPR013893): Ribonuclease P 40kDa (Rpp40) subunit
Spt5-NGN (PF03439, IPR005100): Early transcription elongation factor of RNA pol II, NGN section
Spt5_N (PF11942, IPR022581): Spt5 transcription elongation factor, acidic N-terminal
DUF3912 (PF13051, IPR025023): Protein of unknown function (DUF3912)
123 TMEM17interactor80.107177.144Transmemb_17 (PF09799, IPR019184): Predicted membrane protein
DUF3043 (PF11241, IPR021403): Protein of unknown function (DUF3043)
124 TMEM256interactor100DUF423 (PF04241, IPR006696): Protein of unknown function (DUF423)
DUF2648 (PF10855, IPR022561): Protein of unknown function (DUF2648)
125 TPD52L2protein found in more fusions50.8330.667TPD52 (PF04201, IPR007327): Tumour protein D52 family
126 TPM4oncoprotein80.214129.680Tropomyosin (PF00261, IPR000533): Tropomyosin
Tropomyosin_1 (PF12718, IPR000533): Tropomyosin like
127 TRIP6interactor70.23841.962DEC-1_N (PF04625, IPR006719): DEC-1 protein, N-terminal region
LIM (PF00412, IPR001781, SM00132): LIM domain
128 TRNT1interactor50.5004.861PolyA_pol (PF01743, IPR002646): Poly A polymerase head domain
PolyA_pol_RNAbd (PF12627, IPR032828): Probable RNA and SrmB- binding site of polymerase A
129 UBA2interactor80.50025.609ThiF (PF00899, IPR000594): ThiF family
UAE_UbL (PF14732, IPR028077): Ubiquitin/SUMO-activating enzyme ubiquitin-like domain
UBA2_C (PF16195, IPR032426): SUMO-activating enzyme subunit 2 C-terminus
130 UBA52interactor80.42931.802Ribosomal_L40e (PF01020, IPR001975): Ribosomal L40e family
VWC (PF00093, IPR001007, SM00214): von Willebrand factor type C domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
131 UBCprotein found in more fusions240.170537.086ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
132 UBL4Ainteractor260.215395.936ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
133 UBQLN1protein found in more fusions110.46759.612Clathrin-link (PF09268, IPR015348): Clathrin, heavy-chain linker
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
XPC-binding (PF09280, IPR015360): XPC-binding domain
ubiquitin (PF00240, IPR000626, SM00213): Ubiquitin family
Fur_reg_FbpB (PF13040, IPR025004): Fur-regulated basic protein B
FAM199X (PF15814, IPR029672): Protein family FAM199X
134 UBXN1interactor120.25576.521Selenoprotein_S (PF06936, IPR009703): Selenoprotein S (SelS)
UBA (PF00627, IPR000449, SM00165): UBA/TS-N domain
UBX (PF00789, IPR001012, SM00166): UBX domain
135 UFC1interactor40.5001.762UFC1 (PF08694, IPR014806): Ubiquitin-fold modifier-conjugating enzyme 1
136 USP5interactor70.47629.203UCH (PF00443, IPR001394): Ubiquitin carboxyl-terminal hydrolase
zf-UBP (PF02148, IPR001607, SM00290): Zn-finger in ubiquitin-hydrolases and other protein
137 VBP1interactor31.0000Prefoldin (PF02996, IPR004127): Prefoldin subunit
138 WDR45interactor100CNH (PF00780, IPR001180, SM00036): CNH domain
DUF1736 (PF08409, IPR013618): Domain of unknown function (DUF1736)
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
139 WDR77oncoprotein230.359219.934LT-IIB (PF06453, IPR010503): Type II heat-labile enterotoxin , B subunit (LT-IIB)
WD40 (PF00400, IPR001680, SM00320): WD domain, G-beta repeat
ANAPC4_WD40 (PF12894, IPR024977): Anaphase-promoting complex subunit 4 WD40 domain
140 YWHAEoncoprotein140.24292.54714-3-3 (PF00244, IPR023410, SM00101): 14-3-3 protein

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